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G |
ATP7B |
ATPase copper transporting beta |
affects binding multiple interactions |
EXP |
Copper binds to ATP7B protein Cholera Toxin inhibits the reaction [Copper binds to ATP7B protein]; Colforsin inhibits the reaction [Copper binds to ATP7B protein]; Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein]; PRKACA protein inhibits the reaction [Copper binds to ATP7B protein] |
CTD |
PMID:21084060 |
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NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
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G |
GNRH1 |
gonadotropin releasing hormone 1 |
affects binding multiple interactions |
EXP |
Copper binds to GNRH1 protein [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein |
CTD |
PMID:16892001 |
|
NCBI chr14:9,442,971...9,447,521
Ensembl chr14:9,442,971...9,453,035
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G |
IGF1 |
insulin like growth factor 1 |
increases expression |
EXP |
Copper results in increased expression of IGF1 mRNA |
CTD |
PMID:22367704 |
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NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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|
G |
LHB |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
[Copper binds to GNRH1 protein] which results in increased secretion of LHB protein |
CTD |
PMID:16892001 |
|
NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
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G |
PRKACA |
protein kinase cAMP-activated catalytic subunit alpha |
multiple interactions |
EXP |
PRKACA protein inhibits the reaction [Copper binds to ATP7B protein] |
CTD |
PMID:21084060 |
|
NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551
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|
|
G |
ATP7B |
ATPase copper transporting beta |
multiple interactions affects binding |
EXP |
Cholera Toxin inhibits the reaction [Copper binds to ATP7B protein]; Colforsin inhibits the reaction [Copper binds to ATP7B protein]; Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein]; PRKACA protein inhibits the reaction [Copper binds to ATP7B protein] |
CTD |
PMID:21084060 |
|
NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
|
|
G |
GNRH1 |
gonadotropin releasing hormone 1 |
affects binding multiple interactions |
EXP |
Copper binds to GNRH1 protein [Copper binds to GNRH1 protein] which results in increased secretion of LHB protein |
CTD |
PMID:16892001 |
|
NCBI chr14:9,442,971...9,447,521
Ensembl chr14:9,442,971...9,453,035
|
|
G |
IGF1 |
insulin like growth factor 1 |
increases expression |
EXP |
Copper results in increased expression of IGF1 mRNA |
CTD |
PMID:22367704 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
|
|
G |
LHB |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
[Copper binds to GNRH1 protein] which results in increased secretion of LHB protein |
CTD |
PMID:16892001 |
|
NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
|
|
G |
PRKACA |
protein kinase cAMP-activated catalytic subunit alpha |
multiple interactions |
EXP |
PRKACA protein inhibits the reaction [Copper binds to ATP7B protein] |
CTD |
PMID:21084060 |
|
NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551
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|
|
G |
AOC1 |
amine oxidase copper containing 1 |
increases activity |
EXP |
cupric chloride results in increased activity of AOC1 protein |
CTD |
PMID:16842785 |
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NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
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G |
ATOX1 |
antioxidant 1 copper chaperone |
increases expression |
EXP |
Copper Sulfate results in increased expression of ATOX1 mRNA |
CTD |
PMID:22585802 |
|
NCBI chr16:71,299,321...71,314,598
Ensembl chr16:71,299,321...71,314,597
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G |
CCNB1 |
cyclin B1 |
increases secretion |
EXP |
Copper Sulfate results in increased secretion of CCNB1 protein |
CTD |
PMID:24521407 |
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NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
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G |
COX17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
EXP |
Copper Sulfate results in decreased expression of COX17 mRNA |
CTD |
PMID:22585802 |
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NCBI chr13:140,584,286...140,594,636
Ensembl chr13:140,584,363...140,587,621
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G |
GHRH |
growth hormone releasing hormone |
increases expression |
EXP |
Copper Sulfate results in increased expression of GHRH mRNA |
CTD |
PMID:21110139 |
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NCBI chr17:40,386,725...40,398,312
Ensembl chr17:40,387,344...40,397,857
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
Copper Sulfate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:17464326 |
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NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Copper Sulfate results in increased expression of HSPA5 mRNA |
CTD |
PMID:17464326 |
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NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
IGF1 |
insulin like growth factor 1 |
increases secretion |
EXP |
Copper Sulfate results in increased secretion of IGF1 protein |
CTD |
PMID:24521407 |
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NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
SST |
somatostatin |
decreases expression |
EXP |
Copper Sulfate results in decreased expression of SST mRNA; Copper Sulfate results in decreased expression of SST protein |
CTD |
PMID:21110139 |
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NCBI chr13:125,337,560...125,338,742
Ensembl chr13:125,337,418...125,338,850
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