aryl group - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	aryl group	go back to main search page
Accession:	CHEBI:33338	browse the term
Definition:	A group derived from an arene by removal of a hydrogen atom from a ring carbon atom.
Synonyms:	exact_synonym:	aryl groups
	related_synonym:	Arylgruppe; groupe aryle; grupos arilo

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Genes (802)

2,4,6-trinitrobenzenesulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP-binding cassette, sub-family B member 11

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 protein

NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958

G

ATP-binding cassette, sub-family B member 1A

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]

NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575

G

ATP-binding cassette, sub-family member 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein

NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179

G

actin, beta

increases expression
decreases expression

Trinitrobenzenesulfonic Acid results in increased expression of ACTB mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of ACTB mRNA

PMID:12163651 PMID:17982090

NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509

G

adrenomedullin 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ADM2 mRNA

NCBI chr15:89,206,923...89,208,934
Ensembl chr15:89,206,923...89,208,934

G

advanced glycosylation end product-specific receptor

multiple interactions
increases abundance
increases expression

cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Ager protein in rat colon

CTD
RGD

PMID:33412153 PMID:33522063 PMID:29572553

NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910

G

anterior gradient 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of AGR2 mRNA

NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086

G

aryl-hydrocarbon receptor

multiple interactions

[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid

NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037

G

adenylate kinase 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of AK3 mRNA

NCBI chr19:28,968,715...29,026,122
Ensembl chr19:28,998,233...29,025,361

G

A kinase anchor protein 6

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA]

NCBI chr12:52,745,371...53,202,351
Ensembl chr12:52,746,166...53,202,382

G

A kinase anchor protein 9

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of AKAP9 mRNA

NCBI chr 5:3,977,410...4,130,204
Ensembl chr 5:3,978,054...4,131,310

G

aldo-keto reductase family 1, member C21

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA

NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540

G

albumin

increases secretion

Trinitrobenzenesulfonic Acid results in increased secretion of ALB protein

NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461

G

aldehyde dehydrogenase family 1, subfamily A3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ALDH1A3 mRNA

NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265

G

alkaline phosphatase, intestinal

increases activity
multiple interactions

Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein
Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein]

NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328

G

amylase 2a5

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of AMY2A5 mRNA

NCBI chr 3:113,156,494...113,166,015
Ensembl chr 3:113,154,494...113,166,153

G

annexin A1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA

NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308

G

annexin A8

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ANXA8 mRNA

NCBI chr14:33,807,936...33,822,528
Ensembl chr14:33,807,938...33,822,528

G

amyloid beta precursor protein binding family B member 1 interacting protein

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA

NCBI chr 2:22,645,983...22,765,671
Ensembl chr 2:22,664,106...22,765,665

G

apolipoprotein B

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA

NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835

G

aquaporin 3

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of AQP3 mRNA

NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183

G

aquaporin 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of AQP4 mRNA

NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039

G

ARF interacting protein 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ARFIP1 mRNA

NCBI chr 3:84,403,400...84,490,075
Ensembl chr 3:84,403,733...85,794,825
Ensembl chr 3:84,403,733...85,794,825

G

arginase, liver

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ARG1 mRNA

NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382

G

arginase type II

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA

NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075

G

Rho GTPase activating protein 24

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA]

NCBI chr 5:102,355,043...103,053,743
Ensembl chr 5:102,629,257...103,045,803

G

Rho, GDP dissociation inhibitor beta

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA]

NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897

G

ADP-ribosylation factor-like 4D

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ARL4D mRNA

NCBI chr11:101,556,367...101,558,658
Ensembl chr11:101,556,367...101,558,658

G

arrestin, beta 1

multiple interactions
increases expression

Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein

NCBI chr 7:99,184,356...99,255,979
Ensembl chr 7:99,184,673...99,255,978

G

ADP-ribosyltransferase 2a

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ART2A mRNA

NCBI chr 7:101,201,657...101,210,072
Ensembl chr 7:101,201,660...101,210,072

G

atonal bHLH transcription factor 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of ATOH1 mRNA

NCBI chr 6:64,706,109...64,708,229
Ensembl chr 6:64,706,109...64,708,229

G

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 protein

NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288

G

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ATP4A mRNA

NCBI chr 7:30,411,634...30,424,959
Ensembl chr 7:30,411,634...30,424,959

G

BCL2-antagonist/killer 1

multiple interactions
increases expression

Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAK1 mRNA]

NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983

G

brain abundant, membrane attached signal protein 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of BASP1 mRNA

NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850

G

BCL2-associated X protein

multiple interactions
increases expression

dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BAX protein
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BAX protein]

PMID:15502641 PMID:22427801 PMID:24831514 PMID:31428839 PMID:33412153

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

B cell leukemia/lymphoma 2

multiple interactions
decreases abundance
increases expression
decreases expression

dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Losartan promotes the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]
2,4,6-trinitrobenzenesulfonic acid decreases abundance of Bcl-2 protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein
Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein

CTD
RGD

PMID:15502641 PMID:24637189 PMID:24831514 PMID:31428839 PMID:33412153 More...

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

B cell leukemia/lymphoma 2 related protein A1b

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of BCL2A1B mRNA

NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880

G

BCL2 like 11

multiple interactions
increases expression

[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein]
Trinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein

NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467

G

B cell leukemia/lymphoma 3

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA]

NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695

G

beclin 1, autophagy related

multiple interactions
increases expression

dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]

PMID:30503585 PMID:33412153

NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112

G

bone gamma carboxyglutamate protein

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP protein

NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771

G

bone gamma-carboxyglutamate protein 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP2 mRNA

NCBI chr 3:88,285,043...88,286,008
Ensembl chr 3:88,285,043...88,286,006

G

bone gamma-carboxyglutamate protein 3

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP3 mRNA

NCBI chr 3:88,275,923...88,280,048
Ensembl chr 3:88,275,923...88,280,050

G

biglycan

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA]

NCBI chr X:72,527,207...72,539,542
Ensembl chr X:72,527,208...72,539,539

G

3'(2'), 5'-bisphosphate nucleotidase 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of BPNT2 mRNA

NCBI chr 4:4,762,484...4,793,306
Ensembl chr 4:4,762,484...4,793,355

G

complement component 1, q subcomponent, beta polypeptide

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA]

PMID:17982090 PMID:18200517

NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498

G

complement component 1, q subcomponent, C chain

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of C1QC mRNA

NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376

G

complement component 3

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA]

PMID:17982090 PMID:18200517

NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136

G

complement C4B (Chido blood group)

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA]

NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856

G

complement component 4 binding protein

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of C4BP mRNA

NCBI chr 1:130,562,510...130,589,365
Ensembl chr 1:130,562,510...130,589,369

G

calcium binding protein 39

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CAB39 mRNA

NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297

G

calcium channel, voltage-dependent, L type, alpha 1C subunit

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C protein

NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851

G

calcium channel, voltage-dependent, R type, alpha 1E subunit

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E protein

NCBI chr 1:154,266,552...154,760,374
Ensembl chr 1:154,266,477...154,760,247

G

calcitonin-related polypeptide, beta

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CALCB mRNA

NCBI chr 7:114,315,790...114,322,603
Ensembl chr 7:114,317,878...114,322,600

G

calcitonin receptor-like

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CALCRL mRNA

NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755

G

calcium/calmodulin-dependent protein kinase II, beta

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CAMK2B mRNA

NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362

G

capping actin protein, gelsolin like

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA]

NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966

G

calpain 1

multiple interactions
increases expression

Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein]

NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927

G

carbonic anhydrase 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CAR3 mRNA

NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583

G

caspase 1

multiple interactions
increases expression

bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein

PMID:30365937 PMID:30503585

NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290

G

caspase 12

multiple interactions
increases cleavage

Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein]

NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032

G

caspase 3

multiple interactions
increases expression

D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein
Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein

PMID:22427801 PMID:24831514 PMID:26165751 PMID:30503585 PMID:33412153

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 4, apoptosis-related cysteine peptidase

multiple interactions

bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein

NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783

G

caspase 8

decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

G

caspase 9

multiple interactions
increases expression

Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]

NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287

G

catalase

increases expression
decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of CAT mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA]

PMID:17982090 PMID:30503585

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

C-C motif chemokine ligand 2

increases expression
increases secretion
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein
Trinitrobenzenesulfonic Acid results in increased secretion of CCL2 protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein]
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]

PMID:17449585 PMID:17982090 PMID:23307618 PMID:23596210 PMID:30503585

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

C-C motif chemokine ligand 3

multiple interactions
increases expression

[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]

PMID:21599020 PMID:23596210

NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181

G

C-C motif chemokine ligand 4

multiple interactions
increases expression

icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL4 protein]

NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509

G

C-C motif chemokine ligand 7

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA

NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351

G

C-C motif chemokine ligand 9

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CCL9 mRNA

NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462

G

cellular communication network factor 2

multiple interactions
increases expression

stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA]

NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581

G

cellular communication network factor 4

multiple interactions
decreases expression
increases expression

NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of CCN4 mRNA

PMID:19238344 PMID:23537331

NCBI chr15:66,763,337...66,795,050
Ensembl chr15:66,763,169...66,795,050

G

cyclin B1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA

NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078

G

C-C motif chemokine receptor 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CCR2 mRNA

NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594

G

C-C motif chemokine receptor 5

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CCR5 mRNA

PMID:15973123 PMID:17982090

NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736

G

CD14 antigen

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA

NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851

G

CD3 antigen, gamma polypeptide

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CD3G mRNA

NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729

G

CD44 antigen

multiple interactions
increases expression

seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein]

NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010

G

CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA]

NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373

G

CD53 antigen

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CD53 mRNA

NCBI chr 3:106,666,177...106,697,465
Ensembl chr 3:106,667,237...106,697,465

G

CD55 molecule, decay accelerating factor for complement B

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CD55B mRNA

NCBI chr 1:130,316,263...130,350,831
Ensembl chr 1:130,316,274...130,350,746

G

CD79A antigen (immunoglobulin-associated alpha)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNA

NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622

G

cadherin 17

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CDH17 mRNA

NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895

G

cerebellar degeneration-related 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CDR2 mRNA

NCBI chr 7:120,556,259...120,581,535
Ensembl chr 7:120,556,259...120,581,535

G

CEA cell adhesion molecule 10

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CEACAM10 mRNA

NCBI chr 7:24,476,592...24,484,081
Ensembl chr 7:24,476,631...24,484,082

G

CCAAT/enhancer binding protein beta

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA]

NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338

G

carboxyl ester lipase

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CEL mRNA

NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415

G

chymotrypsin-like elastase family, member 2A

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CELA2A mRNA

NCBI chr 4:141,542,265...141,553,316
Ensembl chr 4:141,542,273...141,553,471

G

carboxylesterase 1D

increases expression
decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA]

PMID:18200517 PMID:19524605 PMID:22609641

NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466

G

carboxylesterase 3B

decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561

G

complement factor D

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CFD mRNA

NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489

G

complement component factor h

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CFH mRNA

NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502

G

chitinase 3 like 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CHI3L1 mRNA

NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919

G

chitinase-like 3

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CHIL3 mRNA]

NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880

G

choline kinase beta

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CHKB mRNA

NCBI chr15:89,310,552...89,314,130
Ensembl chr15:89,310,563...89,314,111

G

chloride channel accessory 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CLCA1 mRNA

NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537

G

chloride channel accessory 4A

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA]

NCBI chr 3:144,658,247...144,680,806
Ensembl chr 3:144,658,241...144,680,806

G

claudin 1

multiple interactions
decreases expression

ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]

PMID:22849695 PMID:39237074

NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591

G

claudin 2

decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]

NCBI chr X:138,701,552...138,712,135
Ensembl chr X:138,701,577...138,712,135

G

collagen, type I, alpha 1

multiple interactions
increases expression

stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA]

PMID:17982090 PMID:25740948

NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868

G

collagen, type I, alpha 2

multiple interactions
increases expression

6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]

PMID:17982090 PMID:18200517 PMID:20889569

NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544

G

collagen, type IV, alpha 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826

G

collagen, type IV, alpha 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA]

NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287

G

collagen, type V, alpha 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA]

NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526

G

collagen, type V, alpha 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA]

NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442

G

cortistatin

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CORT protein

NCBI chr 4:149,209,491...149,211,132
Ensembl chr 4:149,209,491...149,211,220

G

corticotropin releasing hormone

decreases expression
increases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA
Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA

PMID:11668029 PMID:11959675

NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560

G

corticotropin releasing hormone receptor 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CRHR1 mRNA

NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349

G

cysteine-rich secretory protein 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CRISP3 mRNA

NCBI chr17:40,532,668...40,553,179
Ensembl chr17:40,532,668...40,553,179

G

colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA]

NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921

G

colony stimulating factor 3 (granulocyte)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CSF3 protein

NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455

G

cytotoxic T lymphocyte-associated protein 2 alpha

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of CTLA2A mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTLA2A mRNA]

NCBI chr13:61,081,969...61,084,439
Ensembl chr13:61,081,969...61,084,439

G

catenin beta 1

multiple interactions
increases expression

geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

G

chymotrypsinogen B1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CTRB1 mRNA

NCBI chr 8:112,413,142...112,417,642
Ensembl chr 8:112,413,151...112,417,642

G

cathepsin C

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA

NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096

G

C-X3-C motif chemokine ligand 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CX3CL1 mRNA

NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055

G

C-X-C motif chemokine ligand 10

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCL10 protein

NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748

G

C-X-C motif chemokine ligand 12

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA

NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328

G

C-X-C motif chemokine ligand 13

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCL13 mRNA

NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927

G

C-X-C motif chemokine ligand 14

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCL14 mRNA

NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364

G

C-X-C motif chemokine ligand 15

multiple interactions
increases secretion
increases expression

Betamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA]; Tacrolimus inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA]
Trinitrobenzenesulfonic Acid results in increased secretion of CXCL8 protein
Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 protein

PMID:12781210 PMID:20090409 PMID:22609641

NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926

G

C-X-C motif chemokine ligand 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA]

PMID:17375199 PMID:18200517

NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797

G

C-X-C motif chemokine ligand 3

multiple interactions
increases expression

icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein

PMID:17982090 PMID:23596210

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

C-X-C motif chemokine ligand 5

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCL5 mRNA

NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483

G

C-X-C motif chemokine ligand 9

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCL9 mRNA

NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938

G

C-X-C motif chemokine receptor 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of CXCR2 mRNA

NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405

G

cytochrome c, somatic

multiple interactions
increases expression

Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein

PMID:24831514 PMID:30503585

NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein

NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986

G

cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene

multiple interactions

gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein

NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein

NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900

G

cytochrome P450, family 3, subfamily a, polypeptide 11

multiple interactions

[cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of CYP3A11 mRNA; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of CYP3A11 mRNA

NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774

G

cytochrome P450, family 3, subfamily a, polypeptide 13

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of CYP3A13 mRNA

NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881

G

DNA segment, Chr 17, human D6S56E 5

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of D17H6S56E-5 mRNA

NCBI chr17:35,215,654...35,219,722
Ensembl chr17:35,215,654...35,220,489

G

decapping mRNA 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of DCP2 mRNA

NCBI chr18:44,513,567...44,558,036
Ensembl chr18:44,513,569...44,558,036

G

defensin, alpha, 21

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of DEFA5 mRNA

NCBI chr 8:21,515,561...21,516,533
Ensembl chr 8:21,515,561...21,516,532

G

defensin, alpha, 25

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of DEFA25 mRNA

NCBI chr 8:21,574,412...21,575,396
Ensembl chr 8:21,574,458...21,575,301

G

defensin, alpha, 29

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of DEFA29 mRNA

NCBI chr 8:21,815,904...21,817,034
Ensembl chr 8:21,815,903...21,817,036

G

defensin beta 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of DEFB2 mRNA

NCBI chr 8:22,329,942...22,333,519
Ensembl chr 8:22,329,942...22,333,498

G

dynein, axonemal assembly factor 5

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of DNAAF5 mRNA

NCBI chr 5:139,135,888...139,172,265
Ensembl chr 5:139,135,978...139,172,265

G

dipeptidylpeptidase 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of DPP4 mRNA

NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575

G

desmoglein 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of DSG2 mRNA

NCBI chr18:20,691,247...20,737,583
Ensembl chr18:20,691,131...20,737,578

G

eukaryotic translation elongation factor 1 alpha 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA

NCBI chr 9:78,385,735...78,389,006
Ensembl chr 9:78,385,731...78,396,433

G

eukaryotic translation initiation factor 4A2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of EIF4A2 mRNA

NCBI chr16:22,924,846...22,932,882
Ensembl chr16:22,926,194...22,932,886

G

eukaryotic translation initiation factor 4E binding protein 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of EIF4EBP2 mRNA

NCBI chr10:61,268,276...61,288,448
Ensembl chr10:61,264,270...61,288,440

G

embigin

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA]

NCBI chr13:117,357,109...117,410,951
Ensembl chr13:117,345,072...117,410,951

G

Eph receptor B3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of EPHB3 mRNA

NCBI chr16:21,023,530...21,042,054
Ensembl chr16:21,023,505...21,042,055

G

fatty acid binding protein 2, intestinal

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of FABP2 mRNA

NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155

G

Fas ligand

multiple interactions
increases expression

D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of FASL protein]
Trinitrobenzenesulfonic Acid results in increased expression of FASL protein

NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064

G

fibulin 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA]

NCBI chr 6:91,189,442...91,249,522
Ensembl chr 6:91,189,437...91,249,522

G

F-box and leucine-rich repeat protein 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of FBXL2 mRNA

NCBI chr 9:113,787,625...113,855,871
Ensembl chr 9:113,792,705...113,875,259

G

Fc receptor, IgG, low affinity IIb

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of FCGR2B mRNA

NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116

G

Fc receptor, IgG, low affinity IV

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA]

NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330

G

fibroblast growth factor 17

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of FGF17 mRNA

NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708

G

fibroblast growth factor receptor 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of FGFR3 mRNA

NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412

G

fibronectin 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA]

NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359

G

FBJ osteosarcoma oncogene

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of FOS mRNA

NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047

G

formyl peptide receptor 3

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA]

NCBI chr17:18,190,720...18,191,939
Ensembl chr17:18,108,114...18,191,939

G

follistatin-like 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA]

NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876

G

FXYD domain-containing ion transport regulator 5

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of FXYD5 mRNA

NCBI chr 7:30,732,153...30,741,565
Ensembl chr 7:30,732,147...30,741,906

G

gamma-aminobutyric acid type B receptor subunit 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of GABBR1 mRNA

NCBI chr17:37,356,888...37,385,197
Ensembl chr17:37,356,858...37,385,959

G

guanylate binding protein 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of GBP2 mRNA

NCBI chr 3:142,326,424...142,343,769
Ensembl chr 3:142,326,363...142,343,769

G

guanylate binding protein 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of GBP3 mRNA

NCBI chr 3:142,265,781...142,278,974
Ensembl chr 3:142,265,787...142,278,970

G

GTP cyclohydrolase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of GCH1 mRNA

NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

[Trinitrobenzenesulfonic Acid co-treated with Ethanol] results in increased expression of GCLC mRNA

NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767

G

glutamate-cysteine ligase, modifier subunit

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA

NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381

G

guanine deaminase

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA]

NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809

G

glycerophosphodiester phosphodiesterase domain containing 3

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA

NCBI chr 7:126,365,586...126,374,817
Ensembl chr 7:126,365,506...126,374,821

G

glycoprotein galactosyltransferase alpha 1, 3

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA]

NCBI chr 2:35,290,191...35,354,393
Ensembl chr 2:35,290,191...35,353,243

G

glutamic-oxaloacetic transaminase 1, soluble

multiple interactions
decreases expression

Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA]

NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044

G

glutamic-oxaloacetic transaminase 1-like 1

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA]

NCBI chr 8:27,687,487...27,713,872
Ensembl chr 8:27,687,487...27,713,856

G

glutamatic-oxaloacetic transaminase 2, mitochondrial

multiple interactions
decreases expression

Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA]

NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175

G

glutathione peroxidase 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of GPX2 mRNA

NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273

G

growth factor receptor bound protein 10

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA]

NCBI chr11:11,880,499...11,987,428
Ensembl chr11:11,880,508...11,988,683

G

gremlin 1, DAN family BMP antagonist

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA]

NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991

G

glutamate receptor, ionotropic, AMPA2 (alpha 2)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of GRIA2 mRNA

NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142

G

glycogen synthase kinase 3 beta

multiple interactions
increases expression

geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]

NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446

G

gelsolin

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA]

PMID:17982090 PMID:18200517

NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904

G

glutathione reductase

decreases activity
multiple interactions
decreases expression

Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein]; 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA]

NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191

G

glutathione S-transferase, mu 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNA

NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769

G

glutathione S-transferase, theta 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of GSTT1 mRNA

NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418

G

histocompatibility 2, class II antigen A, alpha

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of H2-AA mRNA

NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797

G

histocompatibility 2, class II antigen E alpha

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of H2-EA mRNA

NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618

G

hepatitis A virus cellular receptor 1

increases secretion
increases expression

Trinitrobenzenesulfonic Acid results in increased secretion of HAVCR1 protein
Trinitrobenzenesulfonic Acid results in increased expression of HAVCR1 mRNA

NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405

G

hemoglobin, beta adult minor chain

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HBB-B2 mRNA

G

heme binding protein 2

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA]

NCBI chr10:18,415,871...18,421,824
Ensembl chr10:18,415,246...18,421,824

G

high mobility group box 1

increases expression
increases abundance
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein
2,4,6-trinitrobenzenesulfonic acid increases abundance of Hmgb1 protein in rat colon
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]

CTD
RGD

PMID:33412153 PMID:29572553

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

G

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HMGCR mRNA

NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444

G

heme oxygenase 1

multiple interactions
decreases expression
increases expression

dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Heme promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein

PMID:17292349 PMID:25469038 PMID:30503585 PMID:33412153

NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217

G

homeobox D13

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HOXD13 mRNA

NCBI chr 2:74,498,569...74,501,947
Ensembl chr 2:74,498,654...74,501,943

G

hydroxyprostaglandin dehydrogenase 15 (NAD)

affects expression

Trinitrobenzenesulfonic Acid affects the expression of HPGD mRNA

NCBI chr 8:56,747,587...56,774,081
Ensembl chr 8:56,747,620...56,774,078

G

histamine receptor H4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HRH4 mRNA

NCBI chr18:13,140,039...13,156,758
Ensembl chr18:13,140,047...13,155,939

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA

NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383

G

heat shock protein 5

multiple interactions
increases expression

Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein]

NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559

G

heat shock protein family, member 7 (cardiovascular)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA]

NCBI chr 4:141,148,090...141,152,621
Ensembl chr 4:141,148,090...141,152,622

G

5-hydroxytryptamine (serotonin) receptor 1A

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA

NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630

G

5-hydroxytryptamine (serotonin) receptor 2A

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA

NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934

G

intercellular adhesion molecule 1

multiple interactions
increases abundance
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Icam-1 protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]

CTD
RGD

PMID:18200517 PMID:22029500 PMID:26165751 PMID:30503585 PMID:31428839 More...

NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113

G

indoleamine 2,3-dioxygenase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IDO1 mRNA

NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025

G

interferon activated gene 202B

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFI202B mRNA

NCBI chr 1:173,790,135...173,810,410
Ensembl chr 1:173,790,134...173,810,310

G

interferon activated gene 204

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFI204 mRNA

NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509

G

interferon activated gene 211

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MNDA mRNA

NCBI chr 1:173,723,907...173,740,650
Ensembl chr 1:173,723,911...173,740,612

G

interferon, alpha-inducible protein 27

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of IFI27 mRNA

NCBI chr12:103,400,448...103,406,504
Ensembl chr12:103,400,470...103,406,498

G

interferon gamma inducible protein 30

multiple interactions

[topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA

NCBI chr 8:71,215,418...71,219,307
Ensembl chr 8:71,215,419...71,219,307

G

interferon gamma inducible protein 47

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFI47 mRNA

NCBI chr11:48,967,414...48,987,814
Ensembl chr11:48,967,414...48,987,801

G

interferon induced protein with tetratricpeptide repeats 1B like 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFIT1 mRNA

NCBI chr19:34,570,288...34,640,382
Ensembl chr19:34,570,291...34,579,356

G

interferon-induced protein with tetratricopeptide repeats 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFIT2 mRNA

NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819

G

interferon induced transmembrane protein 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFITM3 mRNA

NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683

G

interferon beta 1, fibroblast

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IFNB1 mRNA

NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011

G

interferon gamma

multiple interactions
increases expression
decreases expression

bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IFNG mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IFNG; Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]

PMID:11717450 PMID:15973123 PMID:16782535 PMID:16867261 PMID:19285099 More...

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

insulin-like growth factor 1

multiple interactions
increases expression

6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein

PMID:18200517 PMID:20889569 PMID:24782617

NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904

G

insulin-like growth factor binding protein 4

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA]

NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218

G

insulin-like growth factor binding protein 5

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043

G

immunoglobulin heavy chain (J558 family)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IGH-VJ558 mRNA

G

Immunoglobulin heavy chain (gamma polypeptide)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IGHG mRNA

G

interferon gamma induced GTPase

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IGTP mRNA

NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417

G

interferon inducible GTPase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IIGP1 mRNA

NCBI chr18:60,506,688...60,525,706
Ensembl chr18:60,509,099...60,525,706

G

interleukin 10

multiple interactions
decreases abundance
decreases secretion
increases expression
decreases expression

[iberogast analog co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; [iberogast co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]
2,4,6-trinitrobenzenesulfonic acid decreases abundance of IL-10 protein in rat colon
Trinitrobenzenesulfonic Acid results in decreased secretion of IL10 protein
Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein
Trinitrobenzenesulfonic Acid results in decreased expression of IL10; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein
[cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]

CTD
RGD

PMID:11717450 PMID:15604057 PMID:15973123 PMID:16867261 PMID:17375199 More...

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

interleukin 12a

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA

NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880

G

interleukin 12b

decreases response to substance
increases expression
multiple interactions

IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid
Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein]
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]

PMID:11782017 PMID:16867261 PMID:17375199 PMID:23596210

NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860

G

interleukin 15

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IL15 protein

NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851

G

interleukin 17A

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of IL17A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]
[Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein

PMID:17375199 PMID:23027085 PMID:27783946 PMID:31428839

NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720

G

interleukin 18

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein]

PMID:15973123 PMID:30365937

NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140

G

interleukin 1 alpha

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein]

PMID:12781210 PMID:23596210

NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892

G

interleukin 1 beta

multiple interactions
increases expression

Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]

PMID:15140218 PMID:15604057 PMID:15793857 PMID:15867298 PMID:15973123 More...

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

G

interleukin 1 receptor, type I

multiple interactions
increases expression

Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]

NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417

G

interleukin 1 receptor-like 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IL1RL1 mRNA

NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575

G

interleukin 1 receptor antagonist

multiple interactions
increases expression

Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]

PMID:15867298 PMID:17375077

NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506

G

interleukin 2

multiple interactions
increases expression

seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL2 mRNA]

PMID:11717450 PMID:27783946

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

G

interleukin 23, alpha subunit p19

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of IL23A mRNA

NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621

G

interleukin 4

increases expression
decreases secretion
decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of IL4 mRNA
Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]

PMID:15973123 PMID:16782535 PMID:16867261 PMID:25729217 PMID:27783946

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

G

interleukin 6

multiple interactions
decreases expression
increases expression

Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IL6 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of IL6; Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein

PMID:17375199 PMID:18079364 PMID:18200517 PMID:19956958 PMID:19998380 More...

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

insulin-like 3

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of INSL3 mRNA

NCBI chr 8:72,141,896...72,143,221
Ensembl chr 8:72,141,858...72,143,219

G

interferon regulatory factor 1

decreases response to substance

IRF1 protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

G

ISG15 ubiquitin-like modifier

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ISG15 mRNA

NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253

G

integral membrane protein 2A

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA]

NCBI chr X:106,440,801...106,446,966
Ensembl chr X:106,440,705...106,446,982

G

inositol 1,4,5-triphosphate receptor 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA

NCBI chr 6:146,009,797...146,403,757
Ensembl chr 6:146,009,797...146,403,721

G

Janus kinase 2

increases phosphorylation
multiple interactions

Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]

NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480

G

jun proto-oncogene

multiple interactions

D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein

NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459

G

potassium voltage-gated channel, shaker-related subfamily, beta member 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of KCNAB1 mRNA

NCBI chr 3:64,856,636...65,285,643
Ensembl chr 3:64,856,617...65,285,644

G

potassium inwardly-rectifying channel, subfamily J, member 4

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of KCNJ4 mRNA

NCBI chr15:79,364,427...79,396,712
Ensembl chr15:79,367,915...79,389,442

G

potassium voltage-gated channel, subfamily Q, member 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of KCNQ4 mRNA

NCBI chr 4:120,553,331...120,605,809
Ensembl chr 4:120,553,335...120,605,809

G

potassium channel tetramerisation domain containing 9

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of KCTD9 mRNA

NCBI chr14:67,953,536...67,979,760
Ensembl chr14:67,953,386...67,979,759

G

kit ligand

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of KITLG mRNA

NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278

G

klotho

multiple interactions
decreases expression

KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of KL protein

NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282

G

L1 cell adhesion molecule

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of L1CAM mRNA

NCBI chr X:72,897,384...72,924,843
Ensembl chr X:72,897,384...72,939,711

G

laminin, alpha 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LAMA3 mRNA

NCBI chr18:12,466,806...12,716,070
Ensembl chr18:12,466,876...12,716,070

G

lipopolysaccharide binding protein

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA]

NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772

G

lipocalin 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264

G

lymphocyte cytosolic protein 1

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA]

NCBI chr14:75,368,570...75,468,282
Ensembl chr14:75,368,541...75,468,282

G

legumain

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA]

NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072

G

leukocyte immunoglobulin-like receptor, subfamily B, member 4B

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LILRB4 mRNA

NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799

G

lysyl oxidase

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA]

PMID:17982090 PMID:18200517

NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939

G

leucine-rich alpha-2-glycoprotein 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA

NCBI chr17:56,426,678...56,428,946
Ensembl chr17:56,426,678...56,429,001

G

leukocyte specific transcript 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LST1 mRNA

NCBI chr17:35,404,071...35,407,416
Ensembl chr17:35,404,071...35,407,415

G

lumican

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LUM mRNA

NCBI chr10:97,401,363...97,408,565
Ensembl chr10:97,400,990...97,408,565

G

lymphocyte antigen 6 family member A

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LY6A mRNA

NCBI chr15:74,866,726...74,869,880
Ensembl chr15:74,866,726...74,869,880

G

lymphocyte antigen 86

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of LY86 mRNA

NCBI chr13:37,529,276...37,603,012
Ensembl chr13:37,529,184...37,603,012

G

lysozyme 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA]

PMID:17982090 PMID:18200517

NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226

G

mucosal vascular addressin cell adhesion molecule 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA]

NCBI chr10:79,500,393...79,504,376
Ensembl chr10:79,500,393...79,504,371

G

MAF bZIP transcription factor

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MAF protein
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF protein]

NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533

G

mesencephalic astrocyte-derived neurotrophic factor

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MANF mRNA

NCBI chr 9:106,765,952...106,769,137
Ensembl chr 9:106,715,511...106,769,178

G

monoamine oxidase A

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA]

NCBI chr X:16,485,937...16,554,051
Ensembl chr X:16,485,937...16,554,057

G

microtubule-associated protein 1 light chain 3 beta

increases lipidation
multiple interactions

Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein]

NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499

G

mitogen-activated protein kinase kinase kinase 6

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of MAP3K6 mRNA

NCBI chr 4:132,965,290...132,980,240
Ensembl chr 4:132,968,129...132,980,240

G

mitogen-activated protein kinase 6

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MAPK6 mRNA

NCBI chr 9:75,294,064...75,317,303
Ensembl chr 9:75,276,344...75,317,287

G

mitogen-activated protein kinase 8

increases expression
increases phosphorylation
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA
Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein
TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein]

PMID:23537331 PMID:39237074

NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115

G

mitogen-activated protein kinase 9

multiple interactions
increases expression

[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein]

NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248

G

MARCKS-like 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MARCKSL1 mRNA

NCBI chr 4:129,407,374...129,409,774
Ensembl chr 4:129,407,374...129,409,778

G

mast cell protease 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MCPT1 mRNA

NCBI chr14:56,255,421...56,257,848
Ensembl chr14:56,255,428...56,257,841

G

mast cell protease 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MCPT2 mRNA

NCBI chr14:56,259,041...56,282,092
Ensembl chr14:56,279,498...56,282,099

G

mast cell protease-like

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MCPTL mRNA

G

malic enzyme 1, NADP(+)-dependent, cytosolic

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNA

NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006

G

matrix Gla protein

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNA

NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821

G

microRNA 155

multiple interactions
increases expression

sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA]

NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092

G

microRNA 29a

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MIR29A mRNA

NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682

G

microRNA 29b-1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MIR29B-1 mRNA

NCBI chr 6:31,039,958...31,040,028
Ensembl chr 6:31,039,958...31,040,028

G

antigen identified by monoclonal antibody Ki 67

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MKI67 mRNA

NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090

G

matrix metallopeptidase 12

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MMP12 mRNA

NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499

G

matrix metallopeptidase 14 (membrane-inserted)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA]

NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821

G

matrix metallopeptidase 15

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MMP15 mRNA

NCBI chr 8:96,078,924...96,100,921
Ensembl chr 8:96,078,896...96,101,708

G

matrix metallopeptidase 1b (interstitial collagenase)

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA]

NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047

G

matrix metallopeptidase 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA]

NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048

G

matrix metallopeptidase 9

multiple interactions

4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein

NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770

G

monooxygenase, DBH-like 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of MOXD2 mRNA

NCBI chr 6:40,855,728...40,864,428
Ensembl chr 6:40,855,728...40,864,428

G

myeloperoxidase

multiple interactions
increases activity
increases expression

4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Indomethacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Spironolactone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; tin protoporphyrin IX promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zileuton inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
2,4,6-trinitrobenzenesulfonic acid increases myeloperoxidase enzyme activity in rat colon
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; J 113397 inhibits the reaction [8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; morphiceptin analog affects the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; RN 1734 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
Trinitrobenzenesulfonic Acid results in increased expression of MPO; Trinitrobenzenesulfonic Acid results in increased expression of MPO protein

CTD
RGD

PMID:10845656 PMID:10877837 PMID:11137876 PMID:11504810 PMID:11668029 More...

NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239

G

mannose receptor, C type 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MRC1 mRNA

NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868

G

mitochondrial rRNA methyltransferase 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MRM3 mRNA

NCBI chr11:76,134,562...76,141,451
Ensembl chr11:76,134,541...76,141,445

G

mitochondrial ribosomal protein L47

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA]

NCBI chr 3:32,781,646...32,790,904
Ensembl chr 3:32,779,546...32,791,754

G

membrane-spanning 4-domains, subfamily A, member 6B

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of MS4A6B mRNA

NCBI chr19:11,495,923...11,507,767
Ensembl chr19:11,493,876...11,508,620

G

moesin

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA]

NCBI chr X:95,139,651...95,212,159
Ensembl chr X:95,139,648...95,212,158

G

mechanistic target of rapamycin kinase

multiple interactions
increases phosphorylation

dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]

NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140

G

mucin 17, cell surface associated

decreases expression
increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of MUC3 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]

PMID:17375077 PMID:17449585

NCBI chr 5:137,163,772...137,202,809
Ensembl chr 5:137,163,770...137,202,830

G

mucin 2

multiple interactions
decreases expression
increases expression

Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNA

PMID:17449585 PMID:19998380 PMID:25307695

NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430

G

mucin 4

multiple interactions
increases expression

Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]

PMID:15867298 PMID:17449585

NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754

G

myeloid differentiation primary response gene 88

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]
Trinitrobenzenesulfonic Acid results in increased expression of MYD88; Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein

PMID:16891783 PMID:19002562 PMID:35290143

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

G

alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

increases secretion

Trinitrobenzenesulfonic Acid results in increased secretion of NAGLU protein

NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498

G

nuclear factor, erythroid derived 2, like 2

multiple interactions
affects expression
decreases expression

4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]

PMID:31428839 PMID:31669340 PMID:33412153

NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985

G

nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

multiple interactions
increases expression

geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]

NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

multiple interactions
decreases expression
increases degradation

bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]

PMID:15793857 PMID:30365937

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

G

nerve growth factor

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of NGF mRNA

NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329

G

NLR family, pyrin domain containing 3

multiple interactions
increases expression

bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein]

NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782

G

N-myristoyltransferase 2

decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA]

NCBI chr 2:3,285,249...3,329,914
Ensembl chr 2:3,285,249...3,329,914

G

nucleotide-binding oligomerization domain containing 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of NOD2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOD2 protein

PMID:16891783 PMID:22147983

NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102

G

nitric oxide synthase 2, inducible

affects response to substance
increases activity
increases expression
multiple interactions

NOS2 protein affects the susceptibility to Trinitrobenzenesulfonic Acid
Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein
Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Sulfasalazine affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]

PMID:10845656 PMID:11504810 PMID:11698051 PMID:11717450 PMID:15867298 More...

NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080

G

neuropeptide Y receptor Y1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of NPY1R mRNA

NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444

G

NAD(P)H dehydrogenase, quinone 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of NQO1 mRNA

PMID:19524605 PMID:22609641 PMID:25724174

NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838

G

nuclear receptor subfamily 1, group H, member 4

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 protein

NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447

G

nuclear receptor subfamily 1, group I, member 2

decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid; [rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid

PMID:21599020 PMID:21829567

NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186

G

nuclear receptor subfamily 2, group F, member 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA

NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876

G

neurotensin

multiple interactions

NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein]

NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347

G

neurotensin receptor 1

multiple interactions
increases response to substance

NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid

NCBI chr 2:180,141,769...180,186,772
Ensembl chr 2:180,141,769...180,186,773

G

nucleobindin 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNA

NCBI chr 7:116,103,579...116,139,823
Ensembl chr 7:116,103,604...116,139,819

G

occludin

multiple interactions
decreases expression

Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]
Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein

PMID:22147983 PMID:22849695 PMID:25307695 PMID:35290143

NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226

G

ornithine decarboxylase, structural 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of ODC1 mRNA

NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506

G

opioid receptor, delta 1

multiple interactions
increases expression

Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein

NCBI chr 4:131,834,980...131,872,042
Ensembl chr 4:131,838,037...131,871,797

G

opioid receptor-like 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of OPRL1 mRNA

NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778

G

olfactory receptor family 2 subfamily H member 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of OR2H1 mRNA

NCBI chr17:37,403,022...37,443,877
Ensembl chr17:37,401,510...37,409,170

G

olfactory receptor family 2 subfamily H member 1B

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of OR2H1B mRNA

NCBI chr17:37,461,923...37,462,861
Ensembl chr17:37,451,309...37,472,385

G

olfactory receptor family 2 subfamily H member 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of OR2H2 mRNA

NCBI chr17:37,396,083...37,397,128
Ensembl chr17:37,394,763...37,399,391

G

olfactory receptor family 2 subfamily H member 2C

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of OR2H2C mRNA

NCBI chr17:37,421,934...37,422,872
Ensembl chr17:37,421,404...37,430,975

G

olfactory receptor family 2 subfamily I member 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of OR2I1 mRNA

NCBI chr17:37,507,697...37,508,857
Ensembl chr17:37,507,316...37,511,885

G

oncostatin M receptor

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA]

PMID:17982090 PMID:18200517

NCBI chr15:6,843,049...6,904,434
Ensembl chr15:6,843,058...6,904,450

G

OTU domain containing 4

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of OTUD4 mRNA

NCBI chr 8:80,366,305...80,404,384
Ensembl chr 8:80,366,247...80,404,353

G

purinergic receptor P2X, ligand-gated ion channel, 7

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA

NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495

G

purinergic receptor P2Y, G-protein coupled 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of P2RY1 mRNA

NCBI chr 3:60,910,206...60,916,403
Ensembl chr 3:60,910,216...60,916,403

G

purinergic receptor P2Y, G-protein coupled 13

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of P2RY13 mRNA

NCBI chr 3:59,115,313...59,118,303
Ensembl chr 3:59,115,313...59,118,303

G

p21 (RAC1) activated kinase 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PAK2 mRNA

NCBI chr16:31,835,108...31,898,160
Ensembl chr16:31,835,108...31,898,160

G

phosphoenolpyruvate carboxykinase 1, cytosolic

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of PCK1 mRNA

NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066

G

proliferating cell nuclear antigen

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PCNA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PCNA protein

NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234

G

protein disulfide isomerase associated 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PDIA3 mRNA

NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168

G

podoplanin

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA]

NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134

G

platelet/endothelial cell adhesion molecule 1

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein]

NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454

G

phosphatidylglycerophosphate synthase 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA]

NCBI chr11:117,876,505...117,914,837
Ensembl chr11:117,877,118...117,914,837

G

pirin

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PIR mRNA

PMID:19524605 PMID:22609641

NCBI chr X:163,052,427...163,156,009
Ensembl chr X:163,052,367...163,156,007

G

paired Ig-like receptor B

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA]

NCBI chr 7:3,715,504...3,723,381
Ensembl chr 7:3,714,408...3,723,390

G

pyruvate kinase liver and red blood cell

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PKLR mRNA

NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091

G

phospholipase A2, group XIIA

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PLA2G12A mRNA

NCBI chr 3:129,672,255...129,689,474
Ensembl chr 3:129,672,255...129,689,474

G

phospholipase A2, group IIA (platelets, synovial fluid)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA]

PMID:17982090 PMID:18200517

NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497

G

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PLA2G7 mRNA

NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA]

NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481

G

pancreatic lipase related protein 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PNLIPRP1 mRNA

NCBI chr19:58,717,319...58,732,601
Ensembl chr19:58,717,319...58,732,601

G

pro-opiomelanocortin-alpha

decreases expression
increases expression

Trinitrobenzenesulfonic Acid results in decreased expression of POMC mRNA
Trinitrobenzenesulfonic Acid results in increased expression of POMC protein

PMID:11959675 PMID:25307695

NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642

G

peroxisome proliferator activated receptor gamma

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein

PMID:16782535 PMID:19617644 PMID:21829567 PMID:24831514 PMID:26165751

NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360

G

protein kinase C, iota

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PRKCI mRNA

NCBI chr 3:31,049,893...31,106,889
Ensembl chr 3:31,049,896...31,107,108

G

serine protease 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PRSS2 mRNA

NCBI chr 6:41,498,710...41,502,013
Ensembl chr 6:41,498,721...41,502,013

G

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PSME3 mRNA

NCBI chr11:101,206,090...101,214,363
Ensembl chr11:101,207,039...101,214,363

G

prostaglandin E receptor 2 (subtype EP2)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PTGER2 mRNA

PMID:23537331 PMID:25526689

NCBI chr14:45,225,568...45,241,277
Ensembl chr14:45,225,652...45,241,277

G

prostaglandin E receptor 4 (subtype EP4)

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of PTGER4 mRNA

NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668

G

prostaglandin E synthase

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PTGES mRNA

NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875

G

prostaglandin I receptor (IP)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PTGIR mRNA

NCBI chr 7:16,640,442...16,644,828
Ensembl chr 7:16,640,415...16,644,830

G

prostaglandin I2 (prostacyclin) synthase

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PTGIS mRNA

NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524

G

prostaglandin-endoperoxide synthase 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of PTGS1 mRNA

NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284

G

prostaglandin-endoperoxide synthase 2

multiple interactions
decreases expression
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of PTGS2 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]

PMID:11137876 PMID:11698051 PMID:11717450 PMID:11820457 PMID:15973123 More...

NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978

G

protein tyrosine phosphatase receptor type C

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PTPRC mRNA

NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446

G

protein tyrosine phosphatase receptor type O

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA]

NCBI chr 6:137,229,189...137,440,251
Ensembl chr 6:137,229,317...137,440,231

G

pentraxin related gene

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA]

NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226

G

RAB10, member RAS oncogene family

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of RAB10 mRNA

NCBI chr12:3,297,428...3,359,969
Ensembl chr12:3,297,428...3,359,969

G

RAB15, member RAS oncogene family

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA

NCBI chr12:76,844,734...76,869,532
Ensembl chr12:76,844,734...76,869,682

G

RAB39, member RAS oncogene family

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RAB39A mRNA

NCBI chr 9:53,595,410...53,617,532
Ensembl chr 9:53,595,410...53,617,532

G

RAB5A, member RAS oncogene family

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RAB5A mRNA

NCBI chr17:53,786,262...53,814,706
Ensembl chr17:53,786,262...53,814,708

G

receptor (calcitonin) activity modifying protein 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RAMP2 mRNA

NCBI chr11:101,137,160...101,139,076
Ensembl chr11:101,136,854...101,150,372

G

receptor (calcitonin) activity modifying protein 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RAMP3 mRNA

NCBI chr11:6,608,507...6,627,478
Ensembl chr11:6,608,521...6,627,475

G

RAS related protein 1b

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RAP1B mRNA

NCBI chr10:117,650,502...117,681,879
Ensembl chr10:117,649,776...117,681,940

G

RAS p21 protein activator 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RASA2 mRNA

NCBI chr 9:96,421,353...96,513,665
Ensembl chr 9:96,421,353...96,513,670

G

RAS p21 protein activator 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RASA3 mRNA

NCBI chr 8:13,617,218...13,727,590
Ensembl chr 8:13,616,948...13,727,603

G

RASD family, member 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of RASD2 mRNA

NCBI chr 8:75,940,572...75,950,741
Ensembl chr 8:75,940,572...75,950,741

G

retinol binding protein 1, cellular

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628

G

retinol dehydrogenase 16

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RDH16 mRNA

NCBI chr10:127,636,959...127,651,715
Ensembl chr10:127,637,021...127,682,434

G

regenerating islet-derived 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of REG2 mRNA

NCBI chr 6:78,382,138...78,385,082
Ensembl chr 6:78,372,606...78,385,089

G

regenerating islet-derived 3 beta

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of REG3B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA]

PMID:17982090 PMID:18200517

NCBI chr 6:78,347,868...78,350,449
Ensembl chr 6:78,347,640...78,350,449

G

regenerating islet-derived 3 delta

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3D mRNA]

NCBI chr 6:78,352,857...78,355,848
Ensembl chr 6:78,352,857...78,355,848

G

regenerating islet-derived 3 gamma

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA]

PMID:17982090 PMID:18200517

NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855

G

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

multiple interactions
increases abundance
increases phosphorylation
increases expression
affects localization

Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Nf-Kb protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of RELA protein
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]

CTD
RGD

PMID:16474422 PMID:19597321 PMID:19956958 PMID:21070844 PMID:22410118 More...

NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158

G

resistin like beta

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA]

NCBI chr16:48,637,219...48,639,255
Ensembl chr16:48,637,219...48,639,255

G

ras homolog family member Q

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RHOQ mRNA

NCBI chr17:87,270,539...87,307,497
Ensembl chr17:87,270,510...87,307,497

G

required for meiotic nuclear division 1 homolog

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of RMND1 mRNA

NCBI chr10:4,353,168...4,382,583
Ensembl chr10:4,351,915...4,382,388

G

ribonuclease, RNase A family, 1 (pancreatic)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNA

NCBI chr14:51,382,459...51,384,224
Ensembl chr14:51,382,455...51,384,242

G

RNA guanylyltransferase and 5'-phosphatase

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RNGTT mRNA

NCBI chr 4:33,310,300...33,502,610
Ensembl chr 4:33,310,311...33,502,614

G

reprimo, TP53 dependent G2 arrest mediator candidate

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of RPRM mRNA

NCBI chr 2:53,974,105...53,975,564
Ensembl chr 2:53,974,105...53,975,564

G

ras responsive element binding protein 1

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA]

NCBI chr13:37,962,362...38,135,981
Ensembl chr13:37,962,376...38,135,981

G

ryanodine receptor 1, skeletal muscle

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA

NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604

G

S100 calcium binding protein A8 (calgranulin A)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342

G

S100 calcium binding protein A9 (calgranulin B)

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028

G

serum amyloid A 3

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SAA3 mRNA

NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124

G

spermidine/spermine N1-acetyl transferase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SAT1 mRNA

NCBI chr X:153,996,128...153,999,345
Ensembl chr X:153,996,128...153,999,445

G

stearoyl-Coenzyme A desaturase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SCD1 mRNA

NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318

G

sodium channel, voltage-gated, type X, alpha

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SCN10A

NCBI chr 9:119,437,522...119,548,388
Ensembl chr 9:119,437,522...119,548,388

G

selenoprotein W

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SELENOW mRNA

NCBI chr 7:15,651,133...15,656,296
Ensembl chr 7:15,651,133...15,656,327

G

serine (or cysteine) peptidase inhibitor, clade A, member 3B

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA]

NCBI chr12:104,094,245...104,105,805
Ensembl chr12:104,094,255...104,105,804

G

serine (or cysteine) peptidase inhibitor, clade B, member 5

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SERPINB5 mRNA

NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078

G

serine (or cysteine) peptidase inhibitor, clade E, member 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA]

NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897

G

sex hormone binding globulin

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNA

NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731

G

sirtuin 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SIRT1 protein

NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483

G

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 protein

NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479

G

solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SLC1A1 mRNA

NCBI chr19:28,812,535...28,891,360
Ensembl chr19:28,812,449...28,891,360

G

solute carrier family 20, member 1

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA]

PMID:17982090 PMID:18200517

NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536

G

solute carrier family 26 (sulfate transporter), member 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SLC26A2 mRNA

NCBI chr18:61,329,926...61,344,668
Ensembl chr18:61,325,991...61,344,684

G

solute carrier family 30, member 10

decreases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA]

NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959

G

solute carrier family 4 (anion exchanger), member 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SLC4A4 mRNA

NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512

G

solute carrier organic anion transporter family, member 1a4

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 protein

NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925

G

solute carrier organic anion transporter family, member 1b2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1B2 mRNA

NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372

G

schlafen 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SLFN4 mRNA

NCBI chr11:83,066,001...83,081,042
Ensembl chr11:83,066,012...83,081,042

G

secretory leukocyte peptidase inhibitor

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA]

NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015

G

structural maintenance of chromosomes 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SMC2 mRNA

NCBI chr 4:52,438,966...52,488,365
Ensembl chr 4:52,439,243...52,488,260

G

small muscle protein, X-linked

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA]

NCBI chr X:156,481,969...156,535,587
Ensembl chr X:156,481,906...156,535,587

G

suppressor of cytokine signaling 3

decreases expression
increases abundance
multiple interactions

Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein
2,4,6-trinitrobenzenesulfonic acid increases abundance of Socs3 protein in rat colon
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]

CTD
RGD

PMID:33522063 PMID:29572553

NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873

G

secreted acidic cysteine rich glycoprotein

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]

PMID:17994277 PMID:18200517

NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009

G

secreted phosphoprotein 1

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA
Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene]

PMID:14555839 PMID:17982090

NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916

G

sequestosome 1

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein]

NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654

G

serglycin

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNA

NCBI chr10:62,329,612...62,363,224
Ensembl chr10:62,329,612...62,363,230

G

spermidine synthase

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA]

NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450

G

signal transducer and activator of transcription 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNA

NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024

G

signal transducer and activator of transcription 3

increases phosphorylation
multiple interactions

Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]

PMID:25740948 PMID:30365937 PMID:33522063

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

stromal interaction molecule 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of STIM1 mRNA

NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526

G

serine/threonine kinase 17b (apoptosis-inducing)

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of STK17B mRNA

NCBI chr 1:53,794,671...53,824,374
Ensembl chr 1:53,794,665...53,824,383

G

sulfatase 2

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA]

NCBI chr 2:165,915,819...165,997,603
Ensembl chr 2:165,915,009...165,997,583

G

sulfotransferase family 1A, phenol-preferring, member 1

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of SULT1A1 mRNA

NCBI chr 7:126,272,042...126,289,615
Ensembl chr 7:126,272,037...126,275,604

G

tachykinin 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA

NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834

G

tachykinin receptor 1

multiple interactions
affects response to substance

TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]
TACR1 protein affects the susceptibility to Trinitrobenzenesulfonic Acid

NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085

G

testin LIM domain protein

multiple interactions
decreases expression

Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of TES protein

NCBI chr 6:17,065,148...17,105,824
Ensembl chr 6:17,065,148...17,105,827

G

trefoil factor 3, intestinal

multiple interactions
increases expression

Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]

PMID:15867298 PMID:17449585

NCBI chr17:31,344,280...31,348,585
Ensembl chr17:31,344,280...31,348,620

G

transforming growth factor, beta 1

multiple interactions
increases expression
decreases expression

6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of TGFB1 protein; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TGFB1 mRNA

PMID:20889569 PMID:21599020 PMID:25307695 PMID:25740948

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

G

transforming growth factor, beta 2

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of TGFB2 mRNA

NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186

G

transforming growth factor, beta receptor I

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TGFBR1 mRNA

NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931

G

transglutaminase 2, C polypeptide

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA]

NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356

G

transglutaminase 3, E polypeptide

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of TGM3 mRNA

NCBI chr 2:129,829,700...129,890,814
Ensembl chr 2:129,854,269...129,892,319

G

T cell specific GTPase 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TGTP1 mRNA

NCBI chr11:48,876,156...48,883,073
Ensembl chr11:48,876,154...48,884,999

G

thrombomodulin

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of THBD mRNA

NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108

G

thrombospondin 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA]

NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614

G

thymus cell antigen 1, theta

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA]

NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876

G

tissue inhibitor of metalloproteinase 1

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein]

PMID:17982090 PMID:18200517 PMID:18837084

NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974

G

tight junction protein 1

multiple interactions
decreases expression

ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein

PMID:22147983 PMID:22849695 PMID:35290143 PMID:39237074

NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529

G

tight junction protein 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TJP2 mRNA

NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394

G

toll-like receptor 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TLR2

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

G

toll-like receptor 4

multiple interactions
increases expression
decreases expression

lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TLR4; Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]

PMID:16891783 PMID:19002562 PMID:19597321 PMID:19956958 PMID:19998380 More...

NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521

G

toll-like receptor 9

multiple interactions
increases expression

oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein]

NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082

G

transmembrane protein 245

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of TMEM245 mRNA

NCBI chr 4:56,866,923...56,947,456
Ensembl chr 4:56,866,923...56,947,437

G

thiol methyltransferase 1A1

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TMT1A mRNA]

NCBI chr15:100,201,969...100,227,882
Ensembl chr15:100,202,021...100,226,543

G

tenascin C

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA]

NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252

G

tumor necrosis factor

multiple interactions
increases abundance
increases expression
increases secretion

[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Tnfa protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of TNF; Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TNF protein
Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; iberogast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]

CTD
RGD

PMID:11717450 PMID:12717850 PMID:16474422 PMID:16782535 PMID:16867261 More...

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

tumor necrosis factor receptor superfamily, member 25

increases response to substance

TNFRSF25 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid

NCBI chr 4:152,199,985...152,204,568
Ensembl chr 4:152,200,391...152,204,576

G

tumor necrosis factor (ligand) superfamily, member 11

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of TNFSF11 protein

NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483

G

tumor necrosis factor (ligand) superfamily, member 15

increases response to substance

TNFSF15 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid

NCBI chr 4:63,642,837...63,663,296
Ensembl chr 4:63,642,840...63,663,350

G

tumor necrosis factor (ligand) superfamily, member 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TNFSF4 mRNA

NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981

G

T cell receptor beta, variable 31

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TRBV31 mRNA

NCBI chr 6:41,534,627...41,535,305
Ensembl chr 6:41,534,627...41,535,386

G

tripartite motif-containing 15

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA]

NCBI chr17:37,171,582...37,179,066
Ensembl chr17:37,171,583...37,178,102

G

tripartite motif-containing 16

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TRIM16 mRNA

PMID:19524605 PMID:22609641

NCBI chr11:62,711,034...62,733,774
Ensembl chr11:62,711,057...62,741,634

G

tripartite motif-containing 30A

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TRIM30A mRNA

NCBI chr 7:104,058,232...104,114,400
Ensembl chr 7:104,058,232...104,114,400

G

thyroid hormone receptor interactor 4

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein]

NCBI chr 9:65,736,208...65,816,150
Ensembl chr 9:65,736,212...65,816,076

G

transformation related protein 53

multiple interactions
increases expression

D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein]
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein
Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein

PMID:22427801 PMID:30503585

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

transient receptor potential cation channel, subfamily C, member 3

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA

NCBI chr 3:36,674,626...36,744,276
Ensembl chr 3:36,674,631...36,744,316

G

transient receptor potential cation channel, subfamily M, member 8

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TRPM8 mRNA

NCBI chr 1:88,234,457...88,318,909
Ensembl chr 1:88,205,383...88,317,015

G

transient receptor potential cation channel, subfamily V, member 1

multiple interactions
increases expression
decreases expression

topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 protein

PMID:17698068 PMID:17991707 PMID:21849664 PMID:25445197

NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068

G

transient receptor potential cation channel, subfamily V, member 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA

NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482

G

transient receptor potential cation channel, subfamily V, member 5

multiple interactions

KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]; Trinitrobenzenesulfonic Acid results in decreased expression of and results in increased metabolism of TRPV5 protein

NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703

G

trypsin 10

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PRSS1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRY10 mRNA

NCBI chr 6:41,331,039...41,334,878
Ensembl chr 6:41,331,039...41,334,848

G

trypsin 4

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of PRSS3 mRNA

NCBI chr 6:41,279,206...41,282,467
Ensembl chr 6:41,279,203...41,282,466

G

thioredoxin domain containing 16

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of TXNDC16 mRNA

NCBI chr14:45,371,905...45,457,008
Ensembl chr14:45,370,922...45,457,785

G

TYRO protein tyrosine kinase binding protein

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA]

PMID:17982090 PMID:18200517

NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010

G

ubiquitin C

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of UBC mRNA

NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266

G

ubiquitin D

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of UBD mRNA

NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986

G

ubiquitin-conjugating enzyme E2W (putative)

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of UBE2W mRNA

NCBI chr 1:16,611,012...16,689,676
Ensembl chr 1:16,611,014...16,689,713

G

UDP glucuronosyltransferase 1 family, polypeptide A6B

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA

NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725

G

UDP glucuronosyltransferase 2 family, polypeptide B5

multiple interactions
decreases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of UGT2B5 mRNA]

NCBI chr 5:87,272,805...87,288,199
Ensembl chr 5:87,272,819...87,288,177

G

ubiquitin specific peptidase 8

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of USP8 mRNA

NCBI chr 2:126,549,280...126,601,234
Ensembl chr 2:126,549,248...126,601,217

G

vascular cell adhesion molecule 1

increases expression
multiple interactions

Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein

PMID:17982090 PMID:22029500 PMID:30503585

NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337

G

versican

multiple interactions
increases expression

Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA]

NCBI chr13:89,803,429...89,891,146
Ensembl chr13:89,803,431...89,890,628

G

vascular endothelial growth factor A

multiple interactions
increases expression

Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]

PMID:21893697 PMID:25307345

NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295

G

vimentin

multiple interactions
increases expression

6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]

NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637

G

vanin 1

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of VNN1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VNN1 protein

NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241

G

Von Willebrand factor

multiple interactions
increases expression

NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein]

NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642

G

WD repeat domain 48

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of WDR48 mRNA

NCBI chr 9:119,723,961...119,755,652
Ensembl chr 9:119,723,944...119,755,653

G

WAP four-disulfide core domain 18

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of WFDC18 mRNA

NCBI chr11:83,599,830...83,602,186
Ensembl chr11:83,599,841...83,602,174

G

zinc finger CCCH type containing 11A

decreases expression

Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNA

NCBI chr 1:133,547,600...133,589,137
Ensembl chr 1:133,547,600...133,589,118

G

zinc finger protein 36, C3H type-like 2

increases expression

Trinitrobenzenesulfonic Acid results in increased expression of ZFP36L2 mRNA

NCBI chr17:84,491,352...84,495,375
Ensembl chr17:84,491,359...84,495,375

2,4-dinitrobenzenesulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenosine deaminase

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of ADA mRNA

NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159

G

adenosine deaminase, RNA-specific, B1

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of ADARB1 mRNA

NCBI chr10:77,126,561...77,254,125
Ensembl chr10:77,126,560...77,254,104

G

adenosine A3 receptor

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 mRNA; 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 protein

NCBI chr 3:105,811,737...105,816,244
Ensembl chr 3:105,778,174...105,816,242

G

activating transcription factor 3

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of ATF3 mRNA

NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236

G

BCL2/adenovirus E1B interacting protein 3

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of BNIP3 mRNA

NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248

G

calcyon neuron-specific vesicular protein

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of CALY mRNA

NCBI chr 7:139,649,793...139,662,485
Ensembl chr 7:139,649,793...139,662,461

G

C-C motif chemokine ligand 7

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of CCL7 mRNA

NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351

G

C-C motif chemokine receptor 2

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of CCR2 mRNA

NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594

G

cadherin 4

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of CDH4 mRNA

NCBI chr 2:179,084,228...179,541,166
Ensembl chr 2:179,084,224...179,541,166

G

cytokine induced apoptosis inhibitor 1

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of CIAPIN1 mRNA

NCBI chr 8:95,546,446...95,565,454
Ensembl chr 8:95,546,432...95,564,986

G

cannabinoid receptor 1

decreases response to substance

CNR1 results in decreased susceptibility to 2,4-dinitrobenzenesulfonic acid

NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831

G

cAMP responsive element binding protein 1

affects expression

2,4-dinitrobenzenesulfonic acid affects the expression of CREB1 mRNA

NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707

G

cytokine receptor-like factor 1

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNA

NCBI chr 8:70,945,798...70,956,728
Ensembl chr 8:70,945,808...70,956,731

G

catenin alpha 3

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of CTNNA3 mRNA

NCBI chr10:63,265,877...64,841,174
Ensembl chr10:63,265,877...64,839,446

G

C-X-C motif chemokine ligand 3

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of CXCL1 mRNA

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

deleted in liver cancer 1

multiple interactions
decreases expression

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of DLC1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of DLC1 mRNA

NCBI chr 8:37,034,893...37,420,343
Ensembl chr 8:37,034,905...37,420,297

G

fatty acid amide hydrolase

increases response to substance

FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid

NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123

G

FAT atypical cadherin 4

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of FAT4 mRNA

NCBI chr 3:38,939,867...39,066,134
Ensembl chr 3:38,941,089...39,066,134

G

four and a half LIM domains 2

multiple interactions

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of FHL2 mRNA

NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144

G

four and a half LIM domains 3

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of FHL3 mRNA

NCBI chr 4:124,589,750...124,602,404
Ensembl chr 4:124,594,494...124,602,404

G

glucosaminyl (N-acetyl) transferase 2 (I blood group)

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of GCNT2 mRNA

NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368

G

glial fibrillary acidic protein

increases expression
multiple interactions

2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA
GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA]

NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738

G

histocompatibility 2, class II antigen A, alpha

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-AA mRNA

NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797

G

histocompatibility 2, T region locus 23

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-T23 mRNA

NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747

G

insulin-like growth factor I receptor

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA

NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416

G

interleukin 10 receptor, alpha

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of IL10RA mRNA

NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447

G

interleukin 6

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of IL6 mRNA

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

inositol 1,3,4-triphosphate 5/6 kinase

multiple interactions
decreases expression

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of ITPK1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of ITPK1 mRNA

NCBI chr12:102,534,842...102,671,128
Ensembl chr12:102,534,841...102,671,189

G

junction adhesion molecule like

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of JAML mRNA

NCBI chr 9:44,990,451...45,019,829
Ensembl chr 9:44,990,481...45,019,832

G

kalirin, RhoGEF kinase

increases expression
multiple interactions

2,4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNA

NCBI chr16:33,789,443...34,393,647
Ensembl chr16:33,789,443...34,393,902

G

potassium voltage gated channel, Shab-related subfamily, member 2

multiple interactions
decreases expression

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KCNB2 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of KCNB2 mRNA

NCBI chr 1:15,357,149...15,793,975
Ensembl chr 1:15,357,478...15,793,974

G

leukemia inhibitory factor

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of LIF mRNA

NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514

G

major facilitator superfamily domain containing 6

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of MFSD6 mRNA

NCBI chr 1:52,695,463...52,766,495
Ensembl chr 1:52,695,445...52,766,621

G

mutS homolog 2

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of MSH2 mRNA

NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141

G

nuclear factor I/X

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of NFIX mRNA

NCBI chr 8:85,431,341...85,527,086
Ensembl chr 8:85,426,505...85,526,973

G

nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

affects expression

2,4-dinitrobenzenesulfonic acid affects the expression of NFKB1 mRNA

NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308

G

5' nucleotidase, ecto

decreases expression
multiple interactions

2,4-dinitrobenzenesulfonic acid results in decreased expression of NT5E mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of NT5E mRNA

NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145

G

ornithine decarboxylase, structural 1

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of ODC1 mRNA

NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506

G

opioid receptor, kappa 1

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of OPRK1 mRNA

NCBI chr 1:5,658,673...5,676,357
Ensembl chr 1:5,658,689...5,676,354

G

protocadherin beta 9

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of PCDHB9 mRNA

NCBI chr18:37,533,908...37,536,962
Ensembl chr18:37,533,908...37,536,962

G

phosphodiesterase 4D, cAMP specific

multiple interactions
decreases expression

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PDE4D mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of PDE4D mRNA

NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995

G

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of PIK3C2A mRNA

NCBI chr 7:115,936,500...116,042,693
Ensembl chr 7:115,936,500...116,042,684

G

proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA

NCBI chr17:34,417,169...34,420,428
Ensembl chr17:34,416,695...34,420,428

G

prostaglandin E receptor 4 (subtype EP4)

multiple interactions
decreases expression

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PTGER4 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of PTGER4 mRNA

NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668

G

ribosomal protein S15A

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of RPS15A mRNA

NCBI chr 7:117,703,597...117,715,370
Ensembl chr 7:117,703,595...117,715,411

G

sarcoglycan, delta (dystrophin-associated glycoprotein)

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of SGCD mRNA

NCBI chr11:46,861,904...47,880,309
Ensembl chr11:46,787,080...47,879,796

G

solute carrier family 9 (sodium/hydrogen exchanger), member 1

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of SLC9A1 mRNA

NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013

G

tachykinin 1

increases expression
multiple interactions

2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA
GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA]

NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834

G

tachykinin receptor 2

multiple interactions

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in decreased expression of TACR2 mRNA

NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769

G

TATA-box binding protein associated factor, RNA polymerase I, B

decreases expression
multiple interactions

2,4-dinitrobenzenesulfonic acid results in decreased expression of TAF1B mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of TAF1B mRNA

NCBI chr12:24,548,580...24,608,570
Ensembl chr12:24,548,358...24,608,538

G

TAP binding protein-like

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of TAPBPL mRNA

NCBI chr 6:125,200,890...125,208,823
Ensembl chr 6:125,200,896...125,208,823

G

thrombospondin 1

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of THBS1 mRNA

NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614

G

tumor necrosis factor

increases expression

2,4-dinitrobenzenesulfonic acid results in increased expression of TNF mRNA

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

tripartite motif-containing 62

decreases expression

2,4-dinitrobenzenesulfonic acid results in decreased expression of TRIM62 mRNA

NCBI chr 4:128,777,837...128,805,119
Ensembl chr 4:128,777,373...128,805,121

G

vesicle transport through interaction with t-SNAREs 1A

multiple interactions
increases expression

[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of VTI1A mRNA
2,4-dinitrobenzenesulfonic acid results in increased expression of VTI1A mRNA

NCBI chr19:55,304,489...55,615,893
Ensembl chr19:55,304,727...55,615,741

3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

catalase

decreases activity

metanil yellow results in decreased activity of CAT protein

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

cyclin B1

multiple interactions

[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein

NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078

G

cyclin D1

increases expression
multiple interactions

metanil yellow results in increased expression of CCND1 protein
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]

PMID:10906429 PMID:12616621

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

cyclin E1

multiple interactions
increases expression

metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein]
metanil yellow results in increased expression of CCNE1 protein

NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959

G

cyclin dependent kinase 1

multiple interactions

[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 protein

NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768

G

cyclin dependent kinase 4

multiple interactions

[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein

NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789

G

follicle stimulating hormone beta

decreases expression

metanil yellow results in decreased expression of FSHB

NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001

G

glutathione reductase

decreases activity

metanil yellow results in decreased activity of GSR protein

NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191

G

luteinizing hormone beta

decreases expression

metanil yellow results in decreased expression of LHB

NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321

G

proliferating cell nuclear antigen

multiple interactions
increases expression

[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of PCNA protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of PCNA protein]
metanil yellow results in increased expression of PCNA protein

PMID:10906429 PMID:11831363 PMID:12616621

NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234

4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

activation-induced cytidine deaminase

increases response to substance
multiple interactions

AICDA results in increased susceptibility to 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein

NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139

G

albumin

decreases uptake

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased uptake of ALB protein

NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461

G

anoctamin 6

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of ANO6 protein

NCBI chr15:95,688,724...95,873,353
Ensembl chr15:95,688,724...95,872,632

G

activating transcription factor 4

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 protein]

NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742

G

caspase 3

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; [Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein

PMID:18590702 PMID:28343033

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 9

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein]

PMID:14766669 PMID:28343033

NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287

G

cystic fibrosis transmembrane conductance regulator

multiple interactions
decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CFTR protein

PMID:15131065 PMID:16038730

NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767

G

chloride channel, voltage-sensitive 3

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLCN3 protein

NCBI chr 8:61,363,423...61,436,351
Ensembl chr 8:61,363,423...61,436,334

G

chloride channel, voltage-sensitive Ka

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKA protein

NCBI chr 4:141,111,922...141,126,017
Ensembl chr 4:141,111,921...141,126,035

G

chloride channel, voltage-sensitive Kb

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKB protein

NCBI chr 4:141,131,668...141,143,440
Ensembl chr 4:141,131,664...141,143,325

G

chloride intracellular channel 1

multiple interactions

[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine

NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725

G

DNA-damage inducible transcript 3

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of DDIT3 protein]

PMID:27638049 PMID:29421517

NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of EIF2AK3 protein modified form]

NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229

G

eukaryotic translation initiation factor 2, subunit 1 alpha

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased phosphorylation of EIF2S1 protein]

NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784

G

heat shock protein 5

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of HSPA5 protein]

NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559

G

interferon gamma

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

interleukin 12b

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]

NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860

G

interleukin 1 beta

affects secretion
multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid affects the secretion of IL1B protein
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of IL1B mRNA]

PMID:15578659 PMID:27461142

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

G

inositol 1,4,5-trisphosphate receptor 1

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ITPR1 protein modified form]

NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070

G

mitogen-activated protein kinase 8

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]

NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115

G

mitogen-activated protein kinase 9

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein]

NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248

G

pannexin 1

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of PANX1 protein

NCBI chr 9:14,917,081...14,956,774
Ensembl chr 9:14,913,424...14,956,774

G

poly (ADP-ribose) polymerase family, member 1

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]

NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819

G

programmed cell death 6 interacting protein

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in decreased expression of PDCD6IP protein]

NCBI chr 9:113,480,812...113,537,457
Ensembl chr 9:113,480,812...113,537,327

G

RAD51 recombinase

decreases activity
multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein

NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926

G

retinoic acid receptor, alpha

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased degradation of RARA protein]

NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768

G

secretin

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SCT protein

NCBI chr 7:140,858,243...140,859,082
Ensembl chr 7:140,858,243...140,859,046

G

solute carrier family 12, member 7

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC12A7 protein

NCBI chr13:73,881,172...73,964,873
Ensembl chr13:73,881,213...73,964,873

G

solute carrier family 19 (folate transporter), member 1

multiple interactions

[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC19A1 protein] which results in decreased uptake of Folic Acid

NCBI chr10:76,868,103...76,886,266
Ensembl chr10:76,868,075...76,896,836

G

solute carrier family 22 (organic anion transporter), member 6

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid]

NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663

G

solute carrier family 46, member 1

multiple interactions
decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC46A1 protein

NCBI chr11:78,356,527...78,362,771
Ensembl chr11:78,356,523...78,362,885

G

solute carrier family 4 (anion exchanger), member 1

multiple interactions
affects binding

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid binds to SLC4A1 protein

NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029

G

solute carrier family 4 (anion exchanger), member 2

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A2 protein results in increased uptake of Benzoic Acid]

NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948

G

solute carrier family 4 (anion exchanger), member 4

decreases activity

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC4A4 protein

NCBI chr 5:88,941,717...89,387,515
Ensembl chr 5:89,034,345...89,387,512

G

solute carrier family 5 (sodium iodide symporter), member 5

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]

NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401

G

sequestosome 1

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of SQSTM1 protein]

NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654

G

transforming growth factor, beta 1

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of TGFB1 mRNA]

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

G

transformation related protein 53

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

voltage-dependent anion channel 1

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Staurosporine promotes the reaction [VDAC1 protein binds to VDAC1 protein]]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC1 protein binds to VDAC1 protein]]

PMID:20937774 PMID:28343033

NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224

G

voltage-dependent anion channel 2

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC2 protein binds to VDAC2 protein]]

NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947

4,4'-dinitrostilbene-2,2'-disulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

solute carrier family 4 (anion exchanger), member 1

multiple interactions

4,4'-dinitro-2,2'-stilbenedisulfonic acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides]

NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029

5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arginine vasopressin

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein]

NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474

G

fibronectin 1

decreases expression

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid results in decreased expression of FN1 mRNA

NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359

G

H2A.X variant histone

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]

NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374

G

interleukin 6

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein]

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

NADPH oxidase 1

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]

NCBI chr X:132,987,170...133,038,455
Ensembl chr X:132,987,170...133,122,705

G

oxytocin

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein]

NCBI chr 2:130,416,432...130,418,974
Ensembl chr 2:130,418,093...130,418,974

G

purinergic receptor P2X, ligand-gated ion channel, 7

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]

PMID:21638035 PMID:31263019

NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495

G

poly (ADP-ribose) polymerase family, member 1

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]

NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819

G

transformation related protein 53 binding protein 1

multiple interactions

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]

NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888

7-amino-4-hydroxy-2-naphthalenesulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

transformation related protein 53

affects activity

7-amino-4-hydroxy-2-naphthalenesulfonic acid affects the activity of TP53 protein; 7-amino-4-hydroxy-2-naphthalenesulfonic acid metabolite affects the activity of TP53 protein

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

8-anilinonaphthalene-1-sulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha 1 microglobulin/bikunin precursor

affects binding

1-anilino-8-naphthalenesulfonate binds to AMBP protein

NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036

G

apolipoprotein D

affects binding

1-anilino-8-naphthalenesulfonate binds to APOD protein

NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626

G

complement component 8, gamma polypeptide

affects binding

1-anilino-8-naphthalenesulfonate binds to C8G protein

NCBI chr 2:25,388,662...25,391,731
Ensembl chr 2:25,388,663...25,391,731

G

lipocalin 11

affects binding

1-anilino-8-naphthalenesulfonate binds to PAEP protein

NCBI chr 2:25,667,029...25,670,291
Ensembl chr 2:25,667,029...25,670,291

G

lipocalin 2

affects binding

1-anilino-8-naphthalenesulfonate binds to LCN2 protein

NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264

G

lipocalin 3

affects binding

1-anilino-8-naphthalenesulfonate binds to LCN1 protein

NCBI chr 2:25,655,545...25,658,110
Ensembl chr 2:25,655,581...25,658,111

G

odorant binding protein 2A

affects binding

1-anilino-8-naphthalenesulfonate binds to OBP2A protein

NCBI chr 2:25,587,589...25,593,338
Ensembl chr 2:25,590,055...25,593,338

G

orosomucoid 1

affects binding

1-anilino-8-naphthalenesulfonate binds to ORM1 protein

NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400

G

prostaglandin D2 synthase (brain)

affects binding

1-anilino-8-naphthalenesulfonate binds to PTGDS protein

NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058

G

transthyretin

affects binding
multiple interactions

1-anilino-8-naphthalenesulfonate binds to TTR protein
3,3'-dichlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 3,4-dichlorinated biphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 4-chlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; Thyroxine inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]

NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378

bathocuproine disulfonic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin, beta

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA]

NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509

G

Rho GDP dissociation inhibitor alpha

multiple interactions

[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA

NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450

G

activating transcription factor 4

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]

NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742

G

antioxidant 1 copper chaperone

multiple interactions

ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 mRNA]; ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein]

NCBI chr11:55,337,463...55,352,034
Ensembl chr11:55,337,467...55,352,065

G

ATPase, copper transporting, alpha polypeptide

multiple interactions

[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]

PMID:11092760 PMID:21242307

NCBI chr X:105,070,830...105,171,766
Ensembl chr X:105,070,882...105,168,532

G

ATPase, copper transporting, beta polypeptide

multiple interactions

[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein]

NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321

G

B cell leukemia/lymphoma 2

decreases expression

bathocuproine sulfonate results in decreased expression of BCL2 protein

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

B cell leukemia/lymphoma 2 related protein A1b

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]

NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880

G

caspase 3

multiple interactions

bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein]

PMID:10941151 PMID:11239917 PMID:18056745

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 8

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

G

C-C motif chemokine ligand 2

multiple interactions

bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

C-C motif chemokine ligand 3

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]

NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181

G

chaperonin containing TCP1 subunit 5

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]

NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950

G

CD200 molecule

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]

NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416

G

CD44 antigen

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]

NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010

G

cadherin 17

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA

NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895

G

clusterin

multiple interactions

[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein]

NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996

G

contactin associated protein-like 1

multiple interactions

[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA

NCBI chr11:101,065,429...101,081,550
Ensembl chr11:101,061,349...101,081,550

G

catechol-O-methyltransferase

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA]

NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602

G

ceruloplasmin

multiple interactions

bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]

NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309

G

cleavage and polyadenylation specific factor 1

multiple interactions

[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA

NCBI chr15:76,480,008...76,491,861
Ensembl chr15:76,480,003...76,491,791

G

cAMP responsive element binding protein 1

multiple interactions

[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA

NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707

G

cAMP responsive element modulator

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]

NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748

G

cullin 5

multiple interactions

[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]

NCBI chr 9:53,525,881...53,578,807
Ensembl chr 9:53,525,882...53,581,314