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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCB11 |
ATP binding cassette subfamily B member 11 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 protein |
CTD |
PMID:12044520 |
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NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein |
CTD |
PMID:12044520 |
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NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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G |
ACTB |
actin beta |
increases expression decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ACTB mRNA Trinitrobenzenesulfonic Acid results in decreased expression of ACTB mRNA |
CTD |
PMID:12163651 PMID:17982090 |
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NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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ADM2 |
adrenomedullin 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ADM2 mRNA |
CTD |
PMID:21808981 |
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NCBI chr22:50,481,543...50,486,437
Ensembl chr22:50,481,543...50,486,440
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G |
AGER |
advanced glycosylation end-product specific receptor |
multiple interactions increases abundance increases expression |
ISO |
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein] 2,4,6-trinitrobenzenesulfonic acid increases abundance of Ager protein in rat colon |
CTD RGD |
PMID:33412153 PMID:33522063 PMID:29572553 |
RGD:152995414 |
NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
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G |
AGR2 |
anterior gradient 2, protein disulphide isomerase family member |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AGR2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433
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AHR |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:21131560 |
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NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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G |
AK3 |
adenylate kinase 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AK3 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
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G |
AKAP6 |
A-kinase anchoring protein 6 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr14:32,329,298...32,837,684
Ensembl chr14:32,329,298...32,837,684
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G |
AKAP9 |
A-kinase anchoring protein 9 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AKAP9 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673
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G |
AKR1C2 |
aldo-keto reductase family 1 member C2 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA |
CTD |
PMID:25724174 |
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NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
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G |
ALB |
albumin |
increases secretion |
ISO |
Trinitrobenzenesulfonic Acid results in increased secretion of ALB protein |
CTD |
PMID:23307618 |
|
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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G |
ALDH1A3 |
aldehyde dehydrogenase 1 family member A3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ALDH1A3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,861,924...100,916,626
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G |
ALPI |
alkaline phosphatase, intestinal |
increases activity multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein] |
CTD |
PMID:15867298 |
|
NCBI chr 2:232,456,153...232,460,753
Ensembl chr 2:232,456,125...232,460,753
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G |
AMY2B |
amylase alpha 2B |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AMY2A5 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:103,554,644...103,579,534
Ensembl chr 1:103,553,815...103,579,534
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G |
ANXA1 |
annexin A1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629
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ANXA8 |
annexin A8 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ANXA8 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:47,467,993...47,991,796
Ensembl chr10:47,460,162...47,484,158
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G |
APBB1IP |
amyloid beta precursor protein binding family B member 1 interacting protein |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:26,438,341...26,567,803
Ensembl chr10:26,438,341...26,568,449
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G |
APOB |
apolipoprotein B |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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G |
AQP3 |
aquaporin 3 (Gill blood group) |
decreases expression |
EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of AQP3 mRNA |
CTD |
PMID:15140218 |
|
NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
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G |
AQP4 |
aquaporin 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of AQP4 mRNA |
CTD |
PMID:23537331 |
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NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
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G |
ARFIP1 |
ARF interacting protein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ARFIP1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 4:152,779,954...152,912,357
Ensembl chr 4:152,779,937...152,918,463
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G |
ARG1 |
arginase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ARG1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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G |
ARG2 |
arginase 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
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G |
ARHGAP24 |
Rho GTPase activating protein 24 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 4:85,475,150...86,002,666
Ensembl chr 4:85,475,150...86,002,668
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G |
ARHGDIB |
Rho GDP dissociation inhibitor beta |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728
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G |
ARL4D |
ARF like GTPase 4D |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ARL4D mRNA |
CTD |
PMID:23537331 |
|
NCBI chr17:43,398,993...43,401,137
Ensembl chr17:43,398,993...43,401,137
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G |
ARRB1 |
arrestin beta 1 |
multiple interactions increases expression |
ISO |
Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein] Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein |
CTD |
PMID:24637189 |
|
NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705
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G |
ART2P |
ADP-ribosyltransferase 2, pseudogene |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ART2A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr11:72,520,951...72,521,640
Ensembl chr11:72,519,986...72,521,733
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G |
ATOH1 |
atonal bHLH transcription factor 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ATOH1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:93,828,753...93,830,964
Ensembl chr 4:93,828,753...93,830,964
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G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 protein |
CTD |
PMID:17131044 |
|
NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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G |
ATP4A |
ATPase H+/K+ transporting subunit alpha |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ATP4A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr19:35,550,031...35,563,658
Ensembl chr19:35,550,031...35,563,658
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G |
BAK1 |
BCL2 antagonist/killer 1 |
multiple interactions increases expression |
ISO |
Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAK1 mRNA] |
CTD |
PMID:15502641 |
|
NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
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G |
BASP1 |
brain abundant membrane attached signal protein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BASP1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:17,216,823...17,276,834
Ensembl chr 5:17,065,598...17,276,843
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO |
dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA] Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BAX protein D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BAX protein] |
CTD |
PMID:15502641 PMID:22427801 PMID:24831514 PMID:31428839 PMID:33412153 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions decreases abundance increases expression decreases expression |
ISO |
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Losartan promotes the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA] 2,4,6-trinitrobenzenesulfonic acid decreases abundance of Bcl-2 protein in rat colon Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein |
CTD RGD |
PMID:15502641 PMID:24637189 PMID:24831514 PMID:31428839 PMID:33412153 PMID:29572553 More...
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RGD:152995414 |
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2A1 |
BCL2 related protein A1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BCL2A1B mRNA |
CTD |
PMID:17982090 |
|
NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
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G |
BCL2L11 |
BCL2 like 11 |
multiple interactions increases expression |
ISO |
[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein] Trinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein |
CTD |
PMID:22427801 |
|
NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
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G |
BCL3 |
BCL3 transcription coactivator |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044
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G |
BECN1 |
beclin 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] |
CTD |
PMID:30503585 PMID:33412153 |
|
NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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G |
BGLAP |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP protein |
CTD |
PMID:23747339 |
|
NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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G |
BGN |
biglycan |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr X:153,494,980...153,509,546
Ensembl chr X:153,494,980...153,509,546
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G |
BPNT2 |
3'(2'), 5'-bisphosphate nucleotidase 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of BPNT2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 8:56,957,931...56,993,867
Ensembl chr 8:56,957,931...56,993,867
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G |
C1QB |
complement C1q B chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
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G |
C1QC |
complement C1q C chain |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of C1QC mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110
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G |
C3 |
complement C3 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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G |
C4B |
complement C4B (Chido/Rodgers blood group) |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
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G |
CA3 |
carbonic anhydrase 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CAR3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
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G |
CAB39 |
calcium binding protein 39 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CAB39 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 2:230,712,842...230,821,075
Ensembl chr 2:230,712,842...230,821,075
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G |
CACNA1C |
calcium voltage-gated channel subunit alpha1 C |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C protein |
CTD |
PMID:23537331 |
|
NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
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G |
CACNA1E |
calcium voltage-gated channel subunit alpha1 E |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E protein |
CTD |
PMID:23537331 |
|
NCBI chr 1:181,317,699...181,808,084
Ensembl chr 1:181,317,690...181,813,262
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G |
CALCB |
calcitonin related polypeptide beta |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CALCB mRNA |
CTD |
PMID:21808981 |
|
NCBI chr11:15,073,593...15,078,637
Ensembl chr11:14,904,997...15,082,342
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G |
CALCRL |
calcitonin receptor like receptor |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CALCRL mRNA |
CTD |
PMID:21808981 |
|
NCBI chr 2:187,341,964...187,448,252
Ensembl chr 2:187,341,964...187,448,460
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G |
CAMK2B |
calcium/calmodulin dependent protein kinase II beta |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CAMK2B mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577
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G |
CAPG |
capping actin protein, gelsolin like |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432
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G |
CAPN1 |
calpain 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] |
CTD |
PMID:30503585 |
|
NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
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G |
CASP1 |
caspase 1 |
multiple interactions increases expression |
ISO |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein |
CTD |
PMID:30365937 PMID:30503585 |
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NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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G |
CASP12 |
caspase 12 (gene/pseudogene) |
increases cleavage multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] |
CTD |
PMID:30503585 |
|
NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670
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G |
CASP3 |
caspase 3 |
multiple interactions increases expression |
ISO |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein |
CTD |
PMID:22427801 PMID:24831514 PMID:26165751 PMID:30503585 PMID:33412153 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASP4 |
caspase 4 |
multiple interactions |
ISO |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein |
CTD |
PMID:30365937 |
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NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366
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G |
CASP8 |
caspase 8 |
multiple interactions decreases expression |
ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] |
CTD |
PMID:30503585 |
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NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CASP9 |
caspase 9 |
multiple interactions increases expression |
ISO |
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form] |
CTD |
PMID:30503585 |
|
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
increases expression multiple interactions decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CAT mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA] |
CTD |
PMID:17982090 PMID:30503585 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCL2 |
C-C motif chemokine ligand 2 |
increases expression increases secretion multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein Trinitrobenzenesulfonic Acid results in increased secretion of CCL2 protein icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein] Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA] |
CTD |
PMID:17449585 PMID:17982090 PMID:23307618 PMID:23596210 PMID:30503585 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL23 |
C-C motif chemokine ligand 23 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCL9 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972
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G |
CCL3 |
C-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein] |
CTD |
PMID:21599020 PMID:23596210 |
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NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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G |
CCL4 |
C-C motif chemokine ligand 4 |
multiple interactions increases expression |
ISO |
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL4 protein] |
CTD |
PMID:23596210 |
|
NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
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G |
CCL7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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G |
CCN2 |
cellular communication network factor 2 |
multiple interactions increases expression |
ISO |
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] |
CTD |
PMID:25740948 |
|
NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
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G |
CCN4 |
cellular communication network factor 4 |
multiple interactions decreases expression increases expression |
ISO |
NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of CCN4 mRNA |
CTD |
PMID:19238344 PMID:23537331 |
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NCBI chr 8:133,191,039...133,231,690
Ensembl chr 8:133,191,039...133,231,690
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G |
CCNB1 |
cyclin B1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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G |
CCR2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCR2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
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G |
CCR5 |
C-C motif chemokine receptor 5 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CCR5 mRNA |
CTD |
PMID:15973123 PMID:17982090 |
|
NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
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G |
CD14 |
CD14 molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
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G |
CD3G |
CD3 gamma subunit of T-cell receptor complex |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CD3G mRNA |
CTD |
PMID:23537331 |
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NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161
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G |
CD44 |
CD44 molecule (IN blood group) |
multiple interactions increases expression |
ISO |
seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein] |
CTD |
PMID:11717450 |
|
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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G |
CD47 |
CD47 molecule |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862
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G |
CD53 |
CD53 molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CD53 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:110,871,210...110,899,922
Ensembl chr 1:110,871,188...110,899,936
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G |
CD79A |
CD79a molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNA |
CTD |
PMID:17982090 |
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NCBI chr19:41,877,279...41,881,372
Ensembl chr19:41,877,279...41,881,372
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G |
CDH17 |
cadherin 17 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CDH17 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
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G |
CDR2 |
cerebellar degeneration related protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CDR2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr16:22,345,936...22,374,619
Ensembl chr16:22,345,936...22,437,165
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G |
CEACAM4 |
CEA cell adhesion molecule 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CEACAM10 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr19:41,613,436...41,627,074
Ensembl chr19:41,619,015...41,627,074
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G |
CEBPB |
CCAAT enhancer binding protein beta |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690
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G |
CEL |
carboxyl ester lipase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CEL mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861
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G |
CELA2A |
chymotrypsin like elastase 2A |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CELA2A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:15,456,732...15,472,091
Ensembl chr 1:15,456,728...15,472,091
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G |
CES1 |
carboxylesterase 1 |
increases expression decreases expression multiple interactions |
EXP ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA] |
CTD |
PMID:18200517 PMID:19524605 PMID:22609641 |
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NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
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G |
CES3 |
carboxylesterase 3 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr16:66,961,266...66,975,149
Ensembl chr16:66,961,245...66,975,149
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G |
CFD |
complement factor D |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CFD mRNA |
CTD |
PMID:17982090 |
|
NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
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G |
CFH |
complement factor H |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CFH mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476
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G |
CHI3L1 |
chitinase 3 like 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CHI3L1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
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G |
CHKB |
choline kinase beta |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CHKB mRNA |
CTD |
PMID:17982090 |
|
NCBI chr22:50,578,963...50,582,849
Ensembl chr22:50,578,959...50,601,455
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G |
CLCA1 |
chloride channel accessory 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CLCA1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259
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G |
CLCA4 |
chloride channel accessory 4 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:86,547,078...86,580,754
Ensembl chr 1:86,547,078...86,580,754
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G |
CLDN1 |
claudin 1 |
multiple interactions decreases expression |
ISO |
ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] |
CTD |
PMID:22849695 PMID:39237074 |
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NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
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G |
CLDN2 |
claudin 2 |
multiple interactions decreases expression |
ISO |
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein] Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein |
CTD |
PMID:35290143 |
|
NCBI chr X:106,900,164...106,930,861
Ensembl chr X:106,900,164...106,930,861
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:17982090 PMID:25740948 |
|
NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
COL1A2 |
collagen type I alpha 2 chain |
multiple interactions increases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA] |
CTD |
PMID:17982090 PMID:18200517 PMID:20889569 |
|
NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
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G |
COL4A1 |
collagen type IV alpha 1 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202
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G |
COL4A2 |
collagen type IV alpha 2 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209
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G |
COL5A1 |
collagen type V alpha 1 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
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G |
COL5A2 |
collagen type V alpha 2 chain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 2:189,031,898...189,441,111
Ensembl chr 2:189,031,898...189,225,312
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G |
CORT |
cortistatin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CORT protein |
CTD |
PMID:11959675 |
|
NCBI chr 1:10,450,031...10,451,998
Ensembl chr 1:10,450,031...10,451,998
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G |
CRH |
corticotropin releasing hormone |
decreases expression increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA |
CTD |
PMID:11668029 PMID:11959675 |
|
NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
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G |
CRHR1 |
corticotropin releasing hormone receptor 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CRHR1 mRNA |
CTD |
PMID:15178552 |
|
NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828
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G |
CRISP3 |
cysteine rich secretory protein 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CRISP3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:49,727,376...49,744,388
Ensembl chr 6:49,727,376...49,744,437
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G |
CSF2RB |
colony stimulating factor 2 receptor subunit beta |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,439
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G |
CSF3 |
colony stimulating factor 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CSF3 protein |
CTD |
PMID:23596210 |
|
NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
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G |
CTNNB1 |
catenin beta 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein] |
CTD |
PMID:26165751 |
|
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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G |
CTRB2 |
chymotrypsinogen B2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CTRB1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr16:75,204,103...75,207,161
Ensembl chr16:75,204,103...75,207,161
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G |
CTSC |
cathepsin C |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA |
CTD |
PMID:17982090 |
|
NCBI chr11:88,293,592...88,337,736
Ensembl chr11:88,265,069...88,359,684
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G |
CX3CL1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CX3CL1 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein] Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein |
CTD |
PMID:17982090 PMID:23596210 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL10 protein |
CTD |
PMID:23596210 |
|
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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G |
CXCL13 |
C-X-C motif chemokine ligand 13 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL13 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834
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|
G |
CXCL14 |
C-X-C motif chemokine ligand 14 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL14 mRNA |
CTD |
PMID:15973123 |
|
NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
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|
G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17375199 PMID:18200517 |
|
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CXCL6 |
C-X-C motif chemokine ligand 6 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL5 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases secretion increases expression |
EXP |
Betamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA]; Tacrolimus inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA] Trinitrobenzenesulfonic Acid results in increased secretion of CXCL8 protein Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL8 protein |
CTD |
PMID:12781210 PMID:20090409 PMID:22609641 |
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CXCL9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCL9 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
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G |
CXCR2 |
C-X-C motif chemokine receptor 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of CXCR2 mRNA |
CTD |
PMID:15973123 |
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NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
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G |
CYCS |
cytochrome c, somatic |
multiple interactions increases expression |
ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA] Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein |
CTD |
PMID:24831514 PMID:30503585 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein |
CTD |
PMID:18079364 |
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NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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G |
CYP2C18 |
cytochrome P450 family 2 subfamily C member 18 |
multiple interactions |
ISO |
gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein |
CTD |
PMID:18079364 |
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NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
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G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein |
CTD |
PMID:18079364 |
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NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
multiple interactions |
ISO |
gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein |
CTD |
PMID:18079364 |
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NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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G |
CYP3A5 |
cytochrome P450 family 3 subfamily A member 5 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of CYP3A13 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
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G |
DCP2 |
decapping mRNA 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of DCP2 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 5:112,976,798...113,022,195
Ensembl chr 5:112,976,702...113,022,195
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G |
DEFA5 |
defensin alpha 5 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of DEFA5 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:7,055,304...7,056,739
Ensembl chr 8:7,055,304...7,056,739
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G |
DNAAF5 |
dynein axonemal assembly factor 5 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of DNAAF5 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:726,699...786,475
Ensembl chr 7:726,699...786,475
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G |
DPP4 |
dipeptidyl peptidase 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of DPP4 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
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G |
DSG2 |
desmoglein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of DSG2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,497,624...31,551,351
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G |
EEF1A1 |
eukaryotic translation elongation factor 1 alpha 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587
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G |
EIF4A2 |
eukaryotic translation initiation factor 4A2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of EIF4A2 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897
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G |
EIF4EBP2 |
eukaryotic translation initiation factor 4E binding protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of EIF4EBP2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:70,404,145...70,428,618
Ensembl chr10:70,404,145...70,428,618
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G |
EMB |
embigin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 5:50,396,192...50,443,345
Ensembl chr 5:50,396,192...50,443,248
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G |
EPHB3 |
EPH receptor B3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of EPHB3 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 3:184,561,785...184,582,408
Ensembl chr 3:184,561,785...184,582,408
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G |
FABP2 |
fatty acid binding protein 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of FABP2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
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G |
FASLG |
Fas ligand |
multiple interactions increases expression |
ISO |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of FASL protein] Trinitrobenzenesulfonic Acid results in increased expression of FASL protein |
CTD |
PMID:22427801 |
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NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FBLN2 |
fibulin 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:13,549,125...13,638,404
Ensembl chr 3:13,549,125...13,638,422
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G |
FBXL2 |
F-box and leucine rich repeat protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of FBXL2 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 3:33,277,025...33,422,698
Ensembl chr 3:33,277,025...33,403,662
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G |
FCGR2B |
Fc gamma receptor IIb |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of FCGR2B mRNA |
CTD |
PMID:19524605 |
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NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654
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G |
FCGR3A |
Fc gamma receptor IIIa |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
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G |
FGF17 |
fibroblast growth factor 17 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of FGF17 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 8:22,039,672...22,048,809
Ensembl chr 8:22,042,398...22,048,809
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G |
FGFR3 |
fibroblast growth factor receptor 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of FGFR3 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872
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G |
FN1 |
fibronectin 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of FOS mRNA |
CTD |
PMID:15178552 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
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G |
FPR3 |
formyl peptide receptor 3 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr19:51,795,157...51,826,190
Ensembl chr19:51,795,157...51,826,190
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G |
FSTL1 |
follistatin like 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:120,392,293...120,450,992
Ensembl chr 3:120,392,293...120,451,016
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G |
FXYD5 |
FXYD domain containing ion transport regulator 5 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of FXYD5 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr19:35,154,735...35,169,881
Ensembl chr19:35,154,730...35,171,791
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G |
GABBR1 |
gamma-aminobutyric acid type B receptor subunit 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GABBR1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976
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G |
GBP2 |
guanylate binding protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GBP2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456
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G |
GBP4 |
guanylate binding protein 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GBP3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:89,181,144...89,198,942
Ensembl chr 1:89,181,144...89,198,942
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G |
GCH1 |
GTP cyclohydrolase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GCH1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions |
ISO |
[Trinitrobenzenesulfonic Acid co-treated with Ethanol] results in increased expression of GCLC mRNA |
CTD |
PMID:10830784 |
|
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA |
CTD |
PMID:22609641 |
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NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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G |
GDA |
guanine deaminase |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193
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G |
GDPD3 |
glycerophosphodiester phosphodiesterase domain containing 3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr16:30,104,810...30,113,537
Ensembl chr16:30,104,810...30,113,537
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G |
GGTA1 |
glycoprotein alpha-galactosyltransferase 1 (inactive) |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 9:121,444,990...121,499,844
Ensembl chr 9:121,444,991...121,499,844
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G |
GOT1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions decreases expression |
ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
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G |
GOT1L1 |
glutamic-oxaloacetic transaminase 1 like 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 8:37,934,281...37,940,124
Ensembl chr 8:37,934,281...37,940,124
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G |
GOT2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] |
CTD |
PMID:30503585 |
|
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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G |
GPX2 |
glutathione peroxidase 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GPX2 mRNA |
CTD |
PMID:31669340 |
|
NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
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G |
GRB10 |
growth factor receptor bound protein 10 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 7:50,590,068...50,793,453
Ensembl chr 7:50,590,063...50,793,462
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G |
GREM1 |
gremlin 1, DAN family BMP antagonist |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106
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G |
GRIA2 |
glutamate ionotropic receptor AMPA type subunit 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GRIA2 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
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G |
GSK3B |
glycogen synthase kinase 3 beta |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] |
CTD |
PMID:26165751 |
|
NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
GSN |
gelsolin |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
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G |
GSR |
glutathione-disulfide reductase |
decreases expression decreases activity multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein]; 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA] |
CTD |
PMID:31669340 |
|
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
GSTM2 |
glutathione S-transferase mu 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
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G |
GSTT1 |
glutathione S-transferase theta 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of GSTT1 mRNA |
CTD |
PMID:31669340 |
|
|
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G |
HAVCR1 |
hepatitis A virus cellular receptor 1 |
increases expression increases secretion |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HAVCR1 mRNA Trinitrobenzenesulfonic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:23307618 |
|
NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
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G |
HEBP2 |
heme binding protein 2 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 6:138,403,531...138,422,197
Ensembl chr 6:138,403,531...138,422,197
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G |
HLA-DQA1 |
major histocompatibility complex, class II, DQ alpha 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of H2-AA mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
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G |
HLA-DRA |
major histocompatibility complex, class II, DR alpha |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of H2-EA mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
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G |
HMGB1 |
high mobility group box 1 |
increases expression increases abundance multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein 2,4,6-trinitrobenzenesulfonic acid increases abundance of Hmgb1 protein in rat colon dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein] |
CTD RGD |
PMID:33412153 PMID:29572553 |
RGD:152995414 |
NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
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G |
HMGCR |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HMGCR mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions decreases expression increases expression |
ISO |
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Heme promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein] Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein |
CTD |
PMID:17292349 PMID:25469038 PMID:30503585 PMID:33412153 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HOXD13 |
homeobox D13 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HOXD13 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:176,087,487...176,095,944
Ensembl chr 2:176,092,721...176,095,944
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G |
HPGD |
15-hydroxyprostaglandin dehydrogenase |
affects expression |
ISO |
Trinitrobenzenesulfonic Acid affects the expression of HPGD mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154
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G |
HRH4 |
histamine receptor H4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HRH4 mRNA |
CTD |
PMID:24561612 |
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NCBI chr18:24,460,637...24,479,974
Ensembl chr18:24,460,637...24,479,961
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G |
HSD11B1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA |
CTD |
PMID:21513799 |
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NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein] |
CTD |
PMID:30503585 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
HSPB7 |
heat shock protein family B (small) member 7 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 1:16,014,029...16,019,594
Ensembl chr 1:16,014,028...16,019,594
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G |
HTR1A |
5-hydroxytryptamine receptor 1A |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA |
CTD |
PMID:23537331 |
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NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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G |
HTR2A |
5-hydroxytryptamine receptor 2A |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA |
CTD |
PMID:23537331 |
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NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
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G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions increases abundance increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] 2,4,6-trinitrobenzenesulfonic acid increases abundance of Icam-1 protein in rat colon Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] |
CTD RGD |
PMID:18200517 PMID:22029500 PMID:26165751 PMID:30503585 PMID:31428839 PMID:33522063 PMID:29572553 More...
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RGD:152995414 |
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
IDO1 |
indoleamine 2,3-dioxygenase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IDO1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
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G |
IFI16 |
interferon gamma inducible protein 16 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFI204 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155
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G |
IFI27 |
interferon alpha inducible protein 27 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of IFI27 mRNA |
CTD |
PMID:17982090 |
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NCBI chr14:94,105,894...94,116,690
Ensembl chr14:94,104,836...94,116,695
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G |
IFI30 |
IFI30 lysosomal thiol reductase |
multiple interactions |
ISO |
[topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA |
CTD |
PMID:21849664 |
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NCBI chr19:18,173,813...18,178,117
Ensembl chr19:18,173,162...18,178,117
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G |
IFIT1 |
interferon induced protein with tetratricopeptide repeats 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFIT1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
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G |
IFIT2 |
interferon induced protein with tetratricopeptide repeats 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFIT2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
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G |
IFITM3 |
interferon induced transmembrane protein 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFITM3 mRNA |
CTD |
PMID:17982090 |
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NCBI chr11:319,676...320,860
Ensembl chr11:319,676...329,475
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G |
IFNB1 |
interferon beta 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IFNB1 mRNA |
CTD |
PMID:17375199 |
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NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
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G |
IFNG |
interferon gamma |
multiple interactions increases expression decreases expression |
ISO EXP |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein] Trinitrobenzenesulfonic Acid results in decreased expression of IFNG mRNA Trinitrobenzenesulfonic Acid results in increased expression of IFNG; Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein] |
CTD |
PMID:11717450 PMID:15973123 PMID:16782535 PMID:16867261 PMID:19285099 PMID:20136961 PMID:21122500 PMID:21599020 PMID:21829567 PMID:22147983 PMID:23027085 PMID:23537331 PMID:23747339 PMID:24066068 PMID:27783946 PMID:30365937 More...
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IGF1 |
insulin like growth factor 1 |
multiple interactions increases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein] Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein |
CTD |
PMID:18200517 PMID:20889569 PMID:24782617 |
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NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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G |
IGFBP4 |
insulin like growth factor binding protein 4 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725
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G |
IGFBP5 |
insulin like growth factor binding protein 5 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
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G |
IL10 |
interleukin 10 |
multiple interactions decreases abundance decreases secretion increases expression decreases expression |
ISO |
[iberogast analog co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; [iberogast co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein] 2,4,6-trinitrobenzenesulfonic acid decreases abundance of IL-10 protein in rat colon Trinitrobenzenesulfonic Acid results in decreased secretion of IL10 protein Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein Trinitrobenzenesulfonic Acid results in decreased expression of IL10; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein [cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein] |
CTD RGD |
PMID:11717450 PMID:15604057 PMID:15973123 PMID:16867261 PMID:17375199 PMID:19196500 PMID:21599020 PMID:21829567 PMID:22060784 PMID:24316276 PMID:24831514 PMID:25307695 PMID:25727887 PMID:25729217 PMID:30365937 PMID:33412153 PMID:35290143 PMID:29572553 More...
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RGD:152995414 |
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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G |
IL12A |
interleukin 12A |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA |
CTD |
PMID:15973123 |
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NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
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G |
IL12B |
interleukin 12B |
decreases response to substance increases expression multiple interactions |
ISO |
IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein] Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] |
CTD |
PMID:11782017 PMID:16867261 PMID:17375199 PMID:23596210 |
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NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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G |
IL15 |
interleukin 15 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL15 protein |
CTD |
PMID:23596210 |
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NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
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G |
IL17A |
interleukin 17A |
increases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of IL17A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein] [Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein |
CTD |
PMID:17375199 PMID:23027085 PMID:27783946 PMID:31428839 |
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NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
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G |
IL18 |
interleukin 18 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] |
CTD |
PMID:15973123 PMID:30365937 |
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NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
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G |
IL1A |
interleukin 1 alpha |
increases expression multiple interactions |
EXP ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein] |
CTD |
PMID:12781210 PMID:23596210 |
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NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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G |
IL1B |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] |
CTD |
PMID:15140218 PMID:15604057 PMID:15793857 PMID:15867298 PMID:15973123 PMID:16782535 PMID:16867261 PMID:17375077 PMID:17375199 PMID:17449585 PMID:17982090 PMID:18200517 PMID:19597321 PMID:19956958 PMID:20868668 PMID:20923188 PMID:21513799 PMID:21829567 PMID:21893697 PMID:22039321 PMID:22060784 PMID:22119283 PMID:22609641 PMID:23596210 PMID:23747339 PMID:25079872 PMID:25307695 PMID:25576893 PMID:25727887 PMID:25729217 PMID:26165751 PMID:30365937 PMID:30503585 PMID:35290143 PMID:39237074 More...
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL1R1 |
interleukin 1 receptor type 1 |
multiple interactions increases expression |
ISO |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] |
CTD |
PMID:17449585 |
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NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
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G |
IL1RL1 |
interleukin 1 receptor like 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL1RL1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
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G |
IL1RN |
interleukin 1 receptor antagonist |
multiple interactions increases expression |
ISO |
Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA] |
CTD |
PMID:15867298 PMID:17375077 |
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NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
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G |
IL2 |
interleukin 2 |
multiple interactions increases expression |
ISO EXP |
seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL2 mRNA] |
CTD |
PMID:11717450 PMID:27783946 |
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NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
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G |
IL23A |
interleukin 23 subunit alpha |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of IL23A mRNA |
CTD |
PMID:17375199 |
|
NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
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G |
IL4 |
interleukin 4 |
increases expression decreases secretion decreases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in increased expression of IL4 mRNA Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein] |
CTD |
PMID:15973123 PMID:16782535 PMID:16867261 PMID:25729217 PMID:27783946 |
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NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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G |
IL6 |
interleukin 6 |
multiple interactions decreases expression increases expression |
ISO |
Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein] Trinitrobenzenesulfonic Acid results in decreased expression of IL6 mRNA Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of IL6; Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein |
CTD |
PMID:17375199 PMID:18079364 PMID:18200517 PMID:19956958 PMID:19998380 PMID:20923188 PMID:21070844 PMID:21829567 PMID:22060784 PMID:22410118 PMID:23027085 PMID:23596210 PMID:23747339 PMID:25307695 PMID:25472953 PMID:25576893 PMID:30503585 PMID:31428839 PMID:33522063 PMID:35290143 PMID:39237074 More...
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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INSL3 |
insulin like 3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of INSL3 mRNA |
CTD |
PMID:23537331 |
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NCBI chr19:17,816,512...17,821,519
Ensembl chr19:17,816,512...17,821,574
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IRF1 |
interferon regulatory factor 1 |
decreases response to substance |
ISO |
IRF1 protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:21097874 |
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NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
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ISG15 |
ISG15 ubiquitin like modifier |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ISG15 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
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ITM2A |
integral membrane protein 2A |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA] |
CTD |
PMID:18200517 |
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NCBI chr X:79,360,384...79,367,334
Ensembl chr X:79,360,384...79,367,667
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ITPR2 |
inositol 1,4,5-trisphosphate receptor type 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA |
CTD |
PMID:23537331 |
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NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194
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JAK2 |
Janus kinase 2 |
increases phosphorylation multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:33522063 |
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NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
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JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein |
CTD |
PMID:22427801 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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KCNAB1 |
potassium voltage-gated channel subfamily A regulatory beta subunit 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of KCNAB1 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 3:156,118,211...156,539,138
Ensembl chr 3:156,037,701...156,538,756
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KCNJ4 |
potassium inwardly rectifying channel subfamily J member 4 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of KCNJ4 mRNA |
CTD |
PMID:23537331 |
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NCBI chr22:38,426,327...38,455,199
Ensembl chr22:38,426,327...38,455,199
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KCNQ4 |
potassium voltage-gated channel subfamily Q member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of KCNQ4 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 1:40,783,787...40,840,452
Ensembl chr 1:40,783,787...40,840,452
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KCTD9 |
potassium channel tetramerization domain containing 9 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of KCTD9 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 8:25,427,847...25,458,433
Ensembl chr 8:25,427,847...25,458,476
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KITLG |
KIT ligand |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of KITLG mRNA |
CTD |
PMID:17385238 |
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NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
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KL |
klotho |
multiple interactions decreases expression |
ISO |
KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein] Trinitrobenzenesulfonic Acid results in decreased expression of KL protein |
CTD |
PMID:23747339 |
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NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
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L1CAM |
L1 cell adhesion molecule |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of L1CAM mRNA |
CTD |
PMID:17982090 |
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NCBI chr X:153,861,514...153,886,173
Ensembl chr X:153,861,514...153,886,173
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LAMA3 |
laminin subunit alpha 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LAMA3 mRNA |
CTD |
PMID:17982090 |
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NCBI chr18:23,689,453...23,955,066
Ensembl chr18:23,689,453...23,956,222
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LBP |
lipopolysaccharide binding protein |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA] |
CTD |
PMID:18200517 |
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NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013
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LCN2 |
lipocalin 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
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LCP1 |
lymphocyte cytosolic protein 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871
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LGMN |
legumain |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr14:92,703,809...92,748,627
Ensembl chr14:92,703,807...92,748,679
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LILRB3 |
leukocyte immunoglobulin like receptor B3 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr19:54,216,278...54,223,007
Ensembl chr19:54,216,278...54,223,506
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LILRB4 |
leukocyte immunoglobulin like receptor B4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LILRB4 mRNA |
CTD |
PMID:17982090 |
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NCBI chr19:54,662,985...54,668,718
Ensembl chr19:54,643,889...54,670,359
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LOX |
lysyl oxidase |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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LRG1 |
leucine rich alpha-2-glycoprotein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036
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LST1 |
leukocyte specific transcript 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LST1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:31,586,277...31,588,909
Ensembl chr 6:31,586,124...31,588,909
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LUM |
lumican |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LUM mRNA |
CTD |
PMID:17982090 |
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NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494
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LY6S |
lymphocyte antigen 6 family member S |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LY6A mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:143,040,839...143,076,471
Ensembl chr 8:143,040,839...143,048,319
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LY86 |
lymphocyte antigen 86 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of LY86 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:6,588,720...6,654,982
Ensembl chr 6:6,588,108...6,654,983
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LYZ |
lysozyme |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234
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MADCAM1 |
mucosal vascular addressin cell adhesion molecule 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr19:496,486...505,343
Ensembl chr19:489,176...505,343
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MAF |
MAF bZIP transcription factor |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MAF protein sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF protein] |
CTD |
PMID:24066068 |
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NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737
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MANF |
mesencephalic astrocyte derived neurotrophic factor |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MANF mRNA |
CTD |
PMID:17982090 |
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NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397
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MAOA |
monoamine oxidase A |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA] |
CTD |
PMID:18200517 |
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NCBI chr X:43,655,006...43,746,817
Ensembl chr X:43,654,907...43,746,817
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MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions increases lipidation |
ISO |
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:30503585 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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MAP3K6 |
mitogen-activated protein kinase kinase kinase 6 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of MAP3K6 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 1:27,355,184...27,366,961
Ensembl chr 1:27,355,184...27,366,961
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MAPK6 |
mitogen-activated protein kinase 6 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MAPK6 mRNA |
CTD |
PMID:23537331 |
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NCBI chr15:51,971,825...52,067,375
Ensembl chr15:51,952,106...52,067,375
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MAPK8 |
mitogen-activated protein kinase 8 |
increases expression increases phosphorylation multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:23537331 PMID:39237074 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAPK9 |
mitogen-activated protein kinase 9 |
multiple interactions increases expression |
ISO |
[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] |
CTD |
PMID:22427801 |
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NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
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MARCKSL1 |
MARCKS like 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MARCKSL1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:32,333,839...32,336,233
Ensembl chr 1:32,333,839...32,336,233
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ME1 |
malic enzyme 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
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MGP |
matrix Gla protein |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNA |
CTD |
PMID:17982090 |
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NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
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MIR155 |
microRNA 155 |
multiple interactions increases expression |
ISO |
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA] |
CTD |
PMID:24066068 |
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NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
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MIR29A |
microRNA 29a |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MIR29A mRNA |
CTD |
PMID:25277410 |
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NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810
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MIR29B1 |
microRNA 29b-1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MIR29B-1 mRNA |
CTD |
PMID:25277410 |
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NCBI chr 7:130,877,459...130,877,539
Ensembl chr 7:130,877,459...130,877,539
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MKI67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MKI67 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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MMP1 |
matrix metallopeptidase 1 |
multiple interactions increases expression |
ISO |
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein |
CTD |
PMID:18837084 |
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NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
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MMP12 |
matrix metallopeptidase 12 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MMP12 mRNA |
CTD |
PMID:17982090 |
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NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
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MMP14 |
matrix metallopeptidase 14 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
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MMP15 |
matrix metallopeptidase 15 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MMP15 mRNA |
CTD |
PMID:17982090 |
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NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901
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MMP2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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MMP9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein |
CTD |
PMID:22119283 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MNDA |
myeloid cell nuclear differentiation antigen |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MNDA mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:158,831,351...158,849,502
Ensembl chr 1:158,831,351...158,849,506
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MOXD2P |
monooxygenase DBH like 2, pseudogene |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of MOXD2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:142,240,737...142,247,067
Ensembl chr 7:142,240,740...142,247,067
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MPO |
myeloperoxidase |
multiple interactions increases activity increases expression |
ISO |
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Indomethacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Spironolactone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; tin protoporphyrin IX promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zileuton inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] 2,4,6-trinitrobenzenesulfonic acid increases myeloperoxidase enzyme activity in rat colon 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; J 113397 inhibits the reaction [8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; morphiceptin analog affects the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; RN 1734 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] Trinitrobenzenesulfonic Acid results in increased expression of MPO; Trinitrobenzenesulfonic Acid results in increased expression of MPO protein |
CTD RGD |
PMID:10845656 PMID:10877837 PMID:11137876 PMID:11504810 PMID:11668029 PMID:11698051 PMID:11959675 PMID:16474422 PMID:16804969 PMID:16867261 PMID:17276891 PMID:17292349 PMID:17375077 PMID:17375199 PMID:17553498 PMID:17936198 PMID:17991707 PMID:18288370 PMID:19002562 PMID:19234664 PMID:19597321 PMID:19956958 PMID:20868668 PMID:21070844 PMID:21599020 PMID:21724996 PMID:21893697 PMID:22029500 PMID:22039321 PMID:22119283 PMID:22410118 PMID:22849695 PMID:22882778 PMID:23596210 PMID:24038091 PMID:24066068 PMID:24101390 PMID:24316276 PMID:24345466 PMID:24831514 PMID:25079872 PMID:25149976 PMID:25445197 PMID:25472953 PMID:25526689 PMID:25576893 PMID:25740948 PMID:26165751 PMID:30365937 PMID:30503585 PMID:31428839 PMID:31669340 PMID:33412153 PMID:33522063 PMID:29572553 More...
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RGD:152995414 |
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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MRC1 |
mannose receptor C-type 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MRC1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164
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MRM3 |
mitochondrial rRNA methyltransferase 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of MRM3 mRNA |
CTD |
PMID:17982090 |
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NCBI chr17:782,353...792,509
Ensembl chr17:782,353...792,509
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MRPL47 |
mitochondrial ribosomal protein L47 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:179,588,285...179,604,646
Ensembl chr 3:179,588,285...179,604,649
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MSN |
moesin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr X:65,588,377...65,741,931
Ensembl chr X:65,588,377...65,741,931
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MTOR |
mechanistic target of rapamycin kinase |
multiple interactions increases phosphorylation |
ISO |
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein] |
CTD |
PMID:33412153 |
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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MUC17 |
mucin 17, cell surface associated |
multiple interactions decreases expression increases expression |
ISO |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of MUC3 mRNA |
CTD |
PMID:17375077 PMID:17449585 |
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NCBI chr 7:101,020,081...101,058,859
Ensembl chr 7:101,020,072...101,058,859
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MUC2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions decreases expression increases expression |
ISO |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNA |
CTD |
PMID:17449585 PMID:19998380 PMID:25307695 |
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NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511
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MUC4 |
mucin 4, cell surface associated |
multiple interactions increases expression |
ISO |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA] |
CTD |
PMID:15867298 PMID:17449585 |
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NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973
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MYD88 |
MYD88 innate immune signal transduction adaptor |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein] Trinitrobenzenesulfonic Acid results in increased expression of MYD88; Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein |
CTD |
PMID:16891783 PMID:19002562 PMID:35290143 |
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NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
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NAGLU |
N-acetyl-alpha-glucosaminidase |
increases secretion |
ISO |
Trinitrobenzenesulfonic Acid results in increased secretion of NAGLU protein |
CTD |
PMID:23307618 |
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NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449
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NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions affects expression decreases expression |
ISO |
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:31428839 PMID:31669340 PMID:33412153 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFKB1 |
nuclear factor kappa B subunit 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] |
CTD |
PMID:26165751 |
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NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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NFKBIA |
NFKB inhibitor alpha |
multiple interactions decreases expression increases degradation |
ISO |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein] |
CTD |
PMID:15793857 PMID:30365937 |
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NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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NGF |
nerve growth factor |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NGF mRNA |
CTD |
PMID:17385238 |
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NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions increases expression |
ISO |
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] |
CTD |
PMID:30365937 |
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NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
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NMT2 |
N-myristoyltransferase 2 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr10:15,105,700...15,168,693
Ensembl chr10:15,102,584...15,168,693
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NOD2 |
nucleotide binding oligomerization domain containing 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NOD2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOD2 protein |
CTD |
PMID:16891783 PMID:22147983 |
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NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077
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NOS2 |
nitric oxide synthase 2 |
affects response to substance increases activity increases expression multiple interactions |
ISO |
NOS2 protein affects the susceptibility to Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Sulfasalazine affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA] Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein] |
CTD |
PMID:10845656 PMID:11504810 PMID:11698051 PMID:11717450 PMID:15867298 PMID:17276891 PMID:17375077 PMID:17449036 PMID:17982090 PMID:19238344 PMID:19285099 PMID:20923188 PMID:21893697 PMID:22039321 PMID:24831514 PMID:30365937 PMID:30503585 PMID:31428839 More...
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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NPY1R |
neuropeptide Y receptor Y1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NPY1R mRNA |
CTD |
PMID:23537331 |
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NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
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NQO1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of NQO1 mRNA |
CTD |
PMID:19524605 PMID:22609641 PMID:25724174 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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NR1H4 |
nuclear receptor subfamily 1 group H member 4 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 protein |
CTD |
PMID:21829567 |
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NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
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NR1I2 |
nuclear receptor subfamily 1 group I member 2 |
decreases expression multiple interactions |
ISO EXP |
Trinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid; [rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:21599020 PMID:21829567 |
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NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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NR2F1 |
nuclear receptor subfamily 2 group F member 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611
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NTS |
neurotensin |
multiple interactions |
ISO |
NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] |
CTD |
PMID:25307345 |
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NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992
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G |
NTSR1 |
neurotensin receptor 1 |
multiple interactions increases response to substance |
ISO |
NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] NTSR1 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:25307345 |
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NCBI chr20:62,708,836...62,762,771
Ensembl chr20:62,708,836...62,762,771
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G |
NUCB2 |
nucleobindin 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980
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OCLN |
occludin |
multiple interactions decreases expression |
ISO |
Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein] oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein] Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein |
CTD |
PMID:22147983 PMID:22849695 PMID:25307695 PMID:35290143 |
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NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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ODC1 |
ornithine decarboxylase 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ODC1 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
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G |
OPRD1 |
opioid receptor delta 1 |
multiple interactions increases expression |
ISO |
Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein] Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein |
CTD |
PMID:24637189 |
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NCBI chr 1:28,812,170...28,871,267
Ensembl chr 1:28,812,170...28,871,267
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G |
OPRL1 |
opioid related nociceptin receptor 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of OPRL1 mRNA |
CTD |
PMID:23537331 |
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NCBI chr20:64,080,082...64,100,643
Ensembl chr20:64,080,082...64,100,643
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G |
OR2H1 |
olfactory receptor family 2 subfamily H member 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of OR2H1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:29,457,155...29,464,328
Ensembl chr 6:29,457,155...29,464,328
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G |
OR2H2 |
olfactory receptor family 2 subfamily H member 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of OR2H2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:29,585,121...29,590,500
Ensembl chr 6:29,585,121...29,590,500
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G |
OR2I1 |
olfactory receptor family 2 subfamily I member 1 (gene/pseudogene) |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of OR2I1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:29,550,407...29,557,773
Ensembl chr 6:29,550,407...29,557,773
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G |
OSMR |
oncostatin M receptor |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596
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G |
OTUD4 |
OTU deubiquitinase 4 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of OTUD4 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 4:145,133,650...145,180,589
Ensembl chr 4:145,110,838...145,180,589
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G |
P2RX7 |
purinergic receptor P2X 7 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA |
CTD |
PMID:23537331 |
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NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
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G |
P2RY1 |
purinergic receptor P2Y1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of P2RY1 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
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G |
P2RY13 |
purinergic receptor P2Y13 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of P2RY13 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 3:151,326,312...151,329,549
Ensembl chr 3:151,326,312...151,329,549
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G |
PAK2 |
p21 (RAC1) activated kinase 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PAK2 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647
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G |
PCK1 |
phosphoenolpyruvate carboxykinase 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of PCK1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
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G |
PCNA |
proliferating cell nuclear antigen |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PCNA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PCNA protein |
CTD |
PMID:19234664 |
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NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
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G |
PDIA3 |
protein disulfide isomerase family A member 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PDIA3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279
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G |
PDPN |
podoplanin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
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G |
PECAM1 |
platelet and endothelial cell adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein] |
CTD |
PMID:22410118 |
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NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
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G |
PGS1 |
phosphatidylglycerophosphate synthase 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr17:78,378,649...78,424,659
Ensembl chr17:78,378,649...78,425,114
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G |
PIR |
pirin |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of PIR mRNA |
CTD |
PMID:19524605 PMID:22609641 |
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NCBI chr X:15,384,799...15,493,333
Ensembl chr X:15,384,799...15,493,564
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G |
PKLR |
pyruvate kinase L/R |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PKLR mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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G |
PLA2G12A |
phospholipase A2 group XIIA |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PLA2G12A mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:109,709,989...109,730,070
Ensembl chr 4:109,709,989...109,730,070
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G |
PLA2G2A |
phospholipase A2 group IIA |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
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G |
PLA2G7 |
phospholipase A2 group VII |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PLA2G7 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
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G |
PLOD2 |
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725
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G |
PNLIPRP1 |
pancreatic lipase related protein 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PNLIPRP1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:116,590,959...116,609,175
Ensembl chr10:116,590,385...116,609,175
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G |
POMC |
proopiomelanocortin |
decreases expression increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of POMC mRNA Trinitrobenzenesulfonic Acid results in increased expression of POMC protein |
CTD |
PMID:11959675 PMID:25307695 |
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NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA] Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein |
CTD |
PMID:16782535 PMID:19617644 PMID:21829567 PMID:24831514 PMID:26165751 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PRKCI |
protein kinase C iota |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PRKCI mRNA |
CTD |
PMID:23537331 |
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NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,424...170,305,977
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G |
PRSS1 |
serine protease 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PRSS1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRY10 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 7:142,749,472...142,753,072
Ensembl chr 7:142,749,468...142,753,072
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G |
PRSS2 |
serine protease 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PRSS2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564
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G |
PRSS3 |
serine protease 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PRSS3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:33,750,679...33,799,231
Ensembl chr 9:33,750,679...33,799,231
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G |
PSME3 |
proteasome activator subunit 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PSME3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr17:42,833,397...42,843,760
Ensembl chr17:42,824,385...42,843,760
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G |
PTGER2 |
prostaglandin E receptor 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTGER2 mRNA |
CTD |
PMID:23537331 PMID:25526689 |
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NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,329,822
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G |
PTGER4 |
prostaglandin E receptor 4 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of PTGER4 mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
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G |
PTGES |
prostaglandin E synthase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTGES mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
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G |
PTGIR |
prostaglandin I2 receptor |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTGIR mRNA |
CTD |
PMID:25526689 |
|
NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,618,550...46,625,089
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G |
PTGIS |
prostaglandin I2 synthase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTGIS mRNA |
CTD |
PMID:25526689 |
|
NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of PTGS1 mRNA |
CTD |
PMID:25526689 |
|
NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein] Trinitrobenzenesulfonic Acid results in decreased expression of PTGS2 mRNA Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein Trinitrobenzenesulfonic Acid results in increased expression of PTGS2; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA] |
CTD |
PMID:11137876 PMID:11698051 PMID:11717450 PMID:11820457 PMID:15973123 PMID:16474422 PMID:16782535 PMID:16804969 PMID:17276891 PMID:17375077 PMID:17375199 PMID:18200517 PMID:19234664 PMID:19956958 PMID:20923188 PMID:21513799 PMID:21893697 PMID:22039321 PMID:24316276 PMID:24831514 PMID:25307695 PMID:25526689 PMID:25576893 PMID:30365937 More...
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTPRC |
protein tyrosine phosphatase receptor type C |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTPRC mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342
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G |
PTPRO |
protein tyrosine phosphatase receptor type O |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr12:15,322,508...15,598,331
Ensembl chr12:15,322,257...15,602,175
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G |
PTX3 |
pentraxin 3 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633
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G |
RAB10 |
RAB10, member RAS oncogene family |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of RAB10 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:26,033,285...26,137,454
Ensembl chr 2:26,034,084...26,137,454
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G |
RAB15 |
RAB15, member RAS oncogene family |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr14:64,945,816...64,972,336
Ensembl chr14:64,945,814...64,973,226
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G |
RAB39A |
RAB39A, member RAS oncogene family |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RAB39A mRNA |
CTD |
PMID:23537331 |
|
NCBI chr11:107,928,448...107,963,482
Ensembl chr11:107,928,448...107,963,482
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G |
RAB5A |
RAB5A, member RAS oncogene family |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RAB5A mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,175
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G |
RAMP2 |
receptor activity modifying protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RAMP2 mRNA |
CTD |
PMID:21808981 |
|
NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041
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G |
RAMP3 |
receptor activity modifying protein 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RAMP3 mRNA |
CTD |
PMID:21808981 |
|
NCBI chr 7:45,157,791...45,184,250
Ensembl chr 7:45,157,791...45,186,302
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G |
RAP1B |
RAP1B, member of RAS oncogene family |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RAP1B mRNA |
CTD |
PMID:23537331 |
|
NCBI chr12:68,610,899...68,671,901
Ensembl chr12:68,610,855...68,671,901
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G |
RASA2 |
RAS p21 protein activator 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RASA2 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 3:141,487,027...141,615,344
Ensembl chr 3:141,487,027...141,615,344
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G |
RASA3 |
RAS p21 protein activator 3 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RASA3 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr13:113,977,783...114,132,623
Ensembl chr13:113,977,783...114,132,623
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G |
RASD2 |
RASD family member 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of RASD2 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr22:35,532,806...35,553,999
Ensembl chr22:35,540,831...35,553,999
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G |
RBP1 |
retinol binding protein 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
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G |
RDH16 |
retinol dehydrogenase 16 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RDH16 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr12:56,951,431...56,957,608
Ensembl chr12:56,951,431...56,959,374
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G |
REG1B |
regenerating family member 1 beta |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of REG2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:79,085,023...79,087,993
Ensembl chr 2:79,085,023...79,088,019
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G |
REG3A |
regenerating family member 3 alpha |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of REG3B mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753
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G |
REG3G |
regenerating family member 3 gamma |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases abundance increases phosphorylation increases expression affects localization |
ISO |
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein] 2,4,6-trinitrobenzenesulfonic acid increases abundance of Nf-Kb protein in rat colon Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of RELA protein lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein] |
CTD RGD |
PMID:16474422 PMID:19597321 PMID:19956958 PMID:21070844 PMID:22410118 PMID:24831514 PMID:33412153 PMID:35290143 PMID:29572553 More...
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RGD:152995414 |
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
RETNLB |
resistin like beta |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 3:108,755,638...108,757,410
Ensembl chr 3:108,743,424...108,757,410
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G |
RHOQ |
ras homolog family member Q |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RHOQ mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:46,542,490...46,584,688
Ensembl chr 2:46,541,806...46,584,688
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G |
RMND1 |
required for meiotic nuclear division 1 homolog |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of RMND1 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:151,404,762...151,452,126
Ensembl chr 6:151,398,898...151,452,158
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G |
RNASE1 |
ribonuclease A family member 1, pancreatic |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr14:20,801,228...20,802,844
Ensembl chr14:20,801,228...20,802,855
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G |
RNGTT |
RNA guanylyltransferase and 5'-phosphatase |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RNGTT mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 6:88,609,897...88,963,618
Ensembl chr 6:88,609,897...88,963,618
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G |
RPRM |
reprimo, TP53 dependent G2 arrest mediator homolog |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of RPRM mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:153,477,338...153,478,762
Ensembl chr 2:153,477,338...153,478,762
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G |
RREB1 |
ras responsive element binding protein 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 6:7,107,743...7,251,980
Ensembl chr 6:7,107,597...7,251,980
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G |
RYR1 |
ryanodine receptor 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
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G |
S100A8 |
S100 calcium binding protein A8 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
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G |
S100A9 |
S100 calcium binding protein A9 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
|
NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
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G |
SAA3P |
serum amyloid A3, pseudogene |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SAA3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132 Ensembl chr11:18,112,472...18,116,132
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G |
SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SAT1 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210
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G |
SCN10A |
sodium voltage-gated channel alpha subunit 10 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SCN10A |
CTD |
PMID:15205116 |
|
NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
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G |
SELENOW |
selenoprotein W |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SELENOW mRNA |
CTD |
PMID:17982090 |
|
NCBI chr19:47,778,703...47,784,682
Ensembl chr19:47,778,677...47,784,686
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G |
SERPINA3 |
serpin family A member 3 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055
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G |
SERPINB5 |
serpin family B member 5 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SERPINB5 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr18:63,476,958...63,505,085
Ensembl chr18:63,476,958...63,505,085
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G |
SERPINE2 |
serpin family E member 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318
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SHBG |
sex hormone binding globulin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNA |
CTD |
PMID:17982090 |
|
NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382
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G |
SIRT1 |
sirtuin 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SIRT1 protein |
CTD |
PMID:24782617 |
|
NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SLC10A1 |
solute carrier family 10 member 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 protein |
CTD |
PMID:12044520 |
|
NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
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G |
SLC1A1 |
solute carrier family 1 member 1 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC1A1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:4,490,468...4,587,469
Ensembl chr 9:4,490,468...4,587,469
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G |
SLC20A1 |
solute carrier family 20 member 1 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825
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G |
SLC26A2 |
solute carrier family 26 member 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC26A2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 5:149,960,758...149,987,400
Ensembl chr 5:149,960,758...149,993,455
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G |
SLC30A10 |
solute carrier family 30 member 10 |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:219,910,445...219,959,098
Ensembl chr 1:219,685,427...219,959,018
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G |
SLC4A4 |
solute carrier family 4 member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SLC4A4 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 protein |
CTD |
PMID:12044520 |
|
NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594
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G |
SLCO1B3 |
solute carrier organic anion transporter family member 1B3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1B2 mRNA |
CTD |
PMID:12044520 |
|
NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911
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G |
SLPI |
secretory leukocyte peptidase inhibitor |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564
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G |
SMC2 |
structural maintenance of chromosomes 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SMC2 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 9:104,088,263...104,141,419
Ensembl chr 9:104,094,260...104,141,419
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G |
SMPX |
small muscle protein X-linked |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr X:21,705,978...21,758,116
Ensembl chr X:21,705,978...21,758,116
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G |
SOCS3 |
suppressor of cytokine signaling 3 |
multiple interactions increases abundance decreases expression |
ISO |
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein] 2,4,6-trinitrobenzenesulfonic acid increases abundance of Socs3 protein in rat colon |
CTD RGD |
PMID:33522063 PMID:29572553 |
RGD:152995414 |
NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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G |
SPARC |
secreted protein acidic and cysteine rich |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA] |
CTD |
PMID:17994277 PMID:18200517 |
|
NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
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G |
SPP1 |
secreted phosphoprotein 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] |
CTD |
PMID:14555839 PMID:17982090 |
|
NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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G |
SQSTM1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] |
CTD |
PMID:33412153 |
|
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRGN |
serglycin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNA |
CTD |
PMID:17982090 |
|
NCBI chr10:69,087,603...69,104,811
Ensembl chr10:69,088,103...69,104,811
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G |
SRM |
spermidine synthase |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020
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G |
STAT1 |
signal transducer and activator of transcription 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
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G |
STAT3 |
signal transducer and activator of transcription 3 |
increases phosphorylation multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:25740948 PMID:30365937 PMID:33522063 |
|
NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
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G |
STIM1 |
stromal interaction molecule 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of STIM1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
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G |
STK17B |
serine/threonine kinase 17b |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of STK17B mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 2:196,133,583...196,176,483
Ensembl chr 2:196,133,583...196,176,503
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G |
SULF2 |
sulfatase 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr20:47,657,406...47,786,627
Ensembl chr20:47,656,197...47,786,616
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G |
SULT1A2 |
sulfotransferase family 1A member 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of SULT1A1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr16:28,591,943...28,597,050
Ensembl chr16:28,591,943...28,597,050
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G |
TAC1 |
tachykinin precursor 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
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G |
TACR1 |
tachykinin receptor 1 |
multiple interactions affects response to substance |
ISO |
TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] TACR1 protein affects the susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:20889569 |
|
NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
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G |
TES |
testin LIM domain protein |
multiple interactions decreases expression |
ISO |
Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein] Trinitrobenzenesulfonic Acid results in decreased expression of TES protein |
CTD |
PMID:39237074 |
|
NCBI chr 7:116,210,539...116,258,783
Ensembl chr 7:116,210,506...116,258,783
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G |
TFF3 |
trefoil factor 3 |
multiple interactions increases expression |
ISO |
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA] |
CTD |
PMID:15867298 PMID:17449585 |
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NCBI chr21:42,311,667...42,315,409
Ensembl chr21:42,311,667...42,315,409
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions increases expression decreases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of TGFB1 protein; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein] Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein Trinitrobenzenesulfonic Acid results in decreased expression of TGFB1 mRNA |
CTD |
PMID:20889569 PMID:21599020 PMID:25307695 PMID:25740948 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TGFB2 |
transforming growth factor beta 2 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TGFB2 mRNA |
CTD |
PMID:25307695 |
|
NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
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G |
TGFBR1 |
transforming growth factor beta receptor 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TGFBR1 mRNA |
CTD |
PMID:23537331 |
|
NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
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G |
TGM2 |
transglutaminase 2 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
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G |
TGM3 |
transglutaminase 3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TGM3 mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:2,296,001...2,341,079
Ensembl chr20:2,296,001...2,341,079
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G |
THBD |
thrombomodulin |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of THBD mRNA |
CTD |
PMID:17982090 |
|
NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
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G |
THBS1 |
thrombospondin 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
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G |
THY1 |
Thy-1 cell surface antigen |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA] |
CTD |
PMID:18200517 |
|
NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985
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G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein] |
CTD |
PMID:17982090 PMID:18200517 PMID:18837084 |
|
NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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G |
TJP1 |
tight junction protein 1 |
multiple interactions decreases expression |
ISO |
ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein] oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein] Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein |
CTD |
PMID:22147983 PMID:22849695 PMID:35290143 PMID:39237074 |
|
NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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G |
TJP2 |
tight junction protein 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TJP2 mRNA |
CTD |
PMID:25307695 |
|
NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615
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G |
TLR2 |
toll like receptor 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TLR2 |
CTD |
PMID:16891783 |
|
NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260
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G |
TLR4 |
toll like receptor 4 |
multiple interactions increases expression decreases expression |
ISO |
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] Trinitrobenzenesulfonic Acid results in increased expression of TLR4; Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] |
CTD |
PMID:16891783 PMID:19002562 PMID:19597321 PMID:19956958 PMID:19998380 PMID:20136961 More...
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NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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G |
TLR9 |
toll like receptor 9 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein] |
CTD |
PMID:35290143 |
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NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
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G |
TMEM245 |
transmembrane protein 245 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TMEM245 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 9:109,015,135...109,119,947
Ensembl chr 9:109,015,135...109,119,947
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G |
TMT1A |
thiol methyltransferase 1A |
decreases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TMT1A mRNA Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TMT1A mRNA] |
CTD |
PMID:18200517 |
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NCBI chr12:50,925,015...50,932,508
Ensembl chr12:50,923,472...50,932,510
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G |
TNC |
tenascin C |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207
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G |
TNF |
tumor necrosis factor |
multiple interactions increases abundance increases expression increases secretion |
ISO EXP |
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] 2,4,6-trinitrobenzenesulfonic acid increases abundance of Tnfa protein in rat colon Trinitrobenzenesulfonic Acid results in increased expression of TNF; Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TNF protein Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; iberogast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] |
CTD RGD |
PMID:11717450 PMID:12717850 PMID:16474422 PMID:16782535 PMID:16867261 PMID:17276891 PMID:17375199 PMID:17449585 PMID:18200517 PMID:19196500 PMID:19285099 PMID:19597321 PMID:19956958 PMID:19998380 PMID:20136961 PMID:20868668 PMID:20923188 PMID:21070844 PMID:21122500 PMID:21513799 PMID:21599020 PMID:21829567 PMID:21893697 PMID:22039321 PMID:22060784 PMID:22119283 PMID:22147983 PMID:22410118 PMID:22427801 PMID:23027085 PMID:23537331 PMID:23596210 PMID:23747339 PMID:24066068 PMID:24316276 PMID:24831514 PMID:25472953 PMID:25576893 PMID:25727887 PMID:25729217 PMID:27783946 PMID:30503585 PMID:33412153 PMID:33522063 PMID:35290143 PMID:39237074 PMID:29572553 More...
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RGD:152995414 |
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFRSF25 |
TNF receptor superfamily member 25 |
increases response to substance |
ISO |
TNFRSF25 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:20980995 |
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NCBI chr 1:6,460,786...6,466,173
Ensembl chr 1:6,460,786...6,466,175
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G |
TNFSF11 |
TNF superfamily member 11 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TNFSF11 protein |
CTD |
PMID:23747339 |
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NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
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TNFSF15 |
TNF superfamily member 15 |
increases response to substance |
ISO |
TNFSF15 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid |
CTD |
PMID:20980995 |
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NCBI chr 9:114,784,635...114,806,039
Ensembl chr 9:114,784,652...114,806,039
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TNFSF4 |
TNF superfamily member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TNFSF4 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583
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TP53 |
tumor protein p53 |
multiple interactions increases expression |
ISO |
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein] Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein |
CTD |
PMID:22427801 PMID:30503585 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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TRBV30 |
T cell receptor beta variable 30 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRBV31 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 7:142,812,586...142,813,287
Ensembl chr 7:142,812,586...142,813,399
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G |
TRIM15 |
tripartite motif containing 15 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693
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TRIM16 |
tripartite motif containing 16 |
increases expression |
EXP |
Trinitrobenzenesulfonic Acid results in increased expression of TRIM16 mRNA |
CTD |
PMID:19524605 PMID:22609641 |
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NCBI chr17:15,627,966...15,684,311
Ensembl chr17:15,627,960...15,684,311
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TRIM22 |
tripartite motif containing 22 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRIM30A mRNA |
CTD |
PMID:17982090 |
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NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089
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TRIP4 |
thyroid hormone receptor interactor 4 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein] |
CTD |
PMID:30365937 |
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NCBI chr15:64,387,836...64,455,303
Ensembl chr15:64,387,748...64,455,303
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TRPC3 |
transient receptor potential cation channel subfamily C member 3 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA |
CTD |
PMID:23537331 |
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NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060
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G |
TRPM8 |
transient receptor potential cation channel subfamily M member 8 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRPM8 mRNA |
CTD |
PMID:23596210 |
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NCBI chr 2:233,917,373...234,019,522
Ensembl chr 2:233,917,373...234,019,522
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G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
multiple interactions increases expression decreases expression |
ISO |
topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 protein |
CTD |
PMID:17698068 PMID:17991707 PMID:21849664 PMID:25445197 |
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NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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TRPV4 |
transient receptor potential cation channel subfamily V member 4 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA |
CTD |
PMID:22882778 |
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NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
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TRPV5 |
transient receptor potential cation channel subfamily V member 5 |
multiple interactions |
ISO |
KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]; Trinitrobenzenesulfonic Acid results in decreased expression of and results in increased metabolism of TRPV5 protein |
CTD |
PMID:23747339 |
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NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
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TXNDC16 |
thioredoxin domain containing 16 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of TXNDC16 mRNA |
CTD |
PMID:17982090 |
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NCBI chr14:52,430,596...52,552,505
Ensembl chr14:52,429,472...52,552,547
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G |
TYROBP |
transmembrane immune signaling adaptor TYROBP |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA] |
CTD |
PMID:17982090 PMID:18200517 |
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NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295
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G |
UBC |
ubiquitin C |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of UBC mRNA |
CTD |
PMID:12163651 |
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NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
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UBD |
ubiquitin D |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of UBD mRNA |
CTD |
PMID:17982090 |
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NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732
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G |
UBE2W |
ubiquitin conjugating enzyme E2 W |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of UBE2W mRNA |
CTD |
PMID:17982090 |
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NCBI chr 8:73,780,096...73,878,862
Ensembl chr 8:73,780,097...73,878,910
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G |
UGT1A6 |
UDP glucuronosyltransferase family 1 member A6 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA |
CTD |
PMID:12163651 |
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NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
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G |
USP8 |
ubiquitin specific peptidase 8 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of USP8 mRNA |
CTD |
PMID:23537331 |
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NCBI chr15:50,424,405...50,514,421
Ensembl chr15:50,424,380...50,514,421
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G |
VCAM1 |
vascular cell adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein |
CTD |
PMID:17982090 PMID:22029500 PMID:30503585 |
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NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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VCAN |
versican |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA] |
CTD |
PMID:18200517 |
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NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
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G |
VEGFA |
vascular endothelial growth factor A |
multiple interactions increases expression |
ISO |
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] |
CTD |
PMID:21893697 PMID:25307345 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VIM |
vimentin |
multiple interactions increases expression |
ISO |
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] |
CTD |
PMID:20889569 |
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NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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G |
VNN1 |
vanin 1 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of VNN1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VNN1 protein |
CTD |
PMID:23307618 |
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NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055
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G |
VWF |
von Willebrand factor |
multiple interactions increases expression |
ISO |
NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] |
CTD |
PMID:25307345 |
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NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
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G |
WDR48 |
WD repeat domain 48 |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of WDR48 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 3:39,052,016...39,096,664
Ensembl chr 3:39,052,013...39,096,671
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G |
ZC3H11A |
zinc finger CCCH-type containing 11A |
decreases expression |
ISO |
Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNA |
CTD |
PMID:17982090 |
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NCBI chr 1:203,795,623...203,854,124
Ensembl chr 1:203,795,623...203,854,999
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G |
ZFP36L2 |
ZFP36 ring finger protein like 2 |
increases expression |
ISO |
Trinitrobenzenesulfonic Acid results in increased expression of ZFP36L2 mRNA |
CTD |
PMID:17982090 |
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NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606
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ADA |
adenosine deaminase |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ADA mRNA |
CTD |
PMID:20860664 |
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NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252
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G |
ADARB1 |
adenosine deaminase RNA specific B1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ADARB1 mRNA |
CTD |
PMID:30116771 |
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NCBI chr21:45,074,578...45,226,563
Ensembl chr21:45,073,853...45,226,560
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G |
ADORA3 |
adenosine A3 receptor |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 mRNA; 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 protein |
CTD |
PMID:20860664 |
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NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
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G |
ATF3 |
activating transcription factor 3 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ATF3 mRNA |
CTD |
PMID:30116771 |
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NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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G |
BNIP3 |
BCL2 interacting protein 3 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of BNIP3 mRNA |
CTD |
PMID:30116771 |
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NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
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G |
CALY |
calcyon neuron specific vesicular protein |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of CALY mRNA |
CTD |
PMID:30116771 |
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NCBI chr10:133,324,072...133,336,896
Ensembl chr10:133,324,072...133,336,935
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G |
CCL7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CCL7 mRNA |
CTD |
PMID:30116771 |
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NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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G |
CCR2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CCR2 mRNA |
CTD |
PMID:30116771 |
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NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
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G |
CDH4 |
cadherin 4 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of CDH4 mRNA |
CTD |
PMID:30116771 |
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NCBI chr20:61,252,261...61,940,617
Ensembl chr20:61,252,261...61,940,617
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G |
CIAPIN1 |
cytokine induced apoptosis inhibitor 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CIAPIN1 mRNA |
CTD |
PMID:30116771 |
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NCBI chr16:57,428,187...57,447,385
Ensembl chr16:57,428,187...57,447,420
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G |
CNR1 |
cannabinoid receptor 1 |
decreases response to substance |
ISO |
CNR1 results in decreased susceptibility to 2,4-dinitrobenzenesulfonic acid |
CTD |
PMID:15085199 |
|
NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
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G |
CREB1 |
cAMP responsive element binding protein 1 |
affects expression |
EXP |
2,4-dinitrobenzenesulfonic acid affects the expression of CREB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CRLF1 |
cytokine receptor like factor 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr19:18,593,237...18,606,799
Ensembl chr19:18,572,220...18,607,741
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G |
CTNNA3 |
catenin alpha 3 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of CTNNA3 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr10:65,912,523...67,763,594
Ensembl chr10:65,912,457...67,763,637
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of CXCL1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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|
G |
DLC1 |
DLC1 Rho GTPase activating protein |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of DLC1 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of DLC1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 8:13,083,361...13,604,620
Ensembl chr 8:13,083,361...13,604,610
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G |
FAAH |
fatty acid amide hydrolase |
increases response to substance |
ISO |
FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid |
CTD |
PMID:15085199 |
|
NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
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G |
FAT4 |
FAT atypical cadherin 4 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of FAT4 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932
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G |
FHL2 |
four and a half LIM domains 2 |
multiple interactions |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of FHL2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513
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G |
FHL3 |
four and a half LIM domains 3 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of FHL3 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:37,996,770...38,005,514
Ensembl chr 1:37,996,764...38,005,606
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G |
GCNT2 |
glucosaminyl (N-acetyl) transferase 2 (I blood group) |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of GCNT2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:10,521,351...10,629,368
Ensembl chr 6:10,492,223...10,629,368
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G |
GFAP |
glial fibrillary acidic protein |
increases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA] |
CTD |
PMID:30116771 |
|
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
HLA-DQA1 |
major histocompatibility complex, class II, DQ alpha 1 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-AA mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
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G |
HLA-E |
major histocompatibility complex, class I, E |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-T23 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194
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G |
IGF1R |
insulin like growth factor 1 receptor |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA |
CTD |
PMID:30116771 |
|
NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
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|
G |
IL10RA |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of IL10RA mRNA |
CTD |
PMID:30116771 |
|
NCBI chr11:117,986,394...118,003,037
Ensembl chr11:117,986,370...118,003,037
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G |
IL6 |
interleukin 6 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of IL6 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
ITPK1 |
inositol-tetrakisphosphate 1-kinase |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of ITPK1 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of ITPK1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr14:92,936,914...93,115,925
Ensembl chr14:92,936,914...93,116,320
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G |
JAML |
junction adhesion molecule like |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of JAML mRNA |
CTD |
PMID:30116771 |
|
NCBI chr11:118,193,725...118,225,011
Ensembl chr11:118,193,725...118,225,092
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G |
KALRN |
kalirin RhoGEF kinase |
multiple interactions increases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNA 2,4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 3:124,033,369...124,726,325
Ensembl chr 3:124,033,369...124,726,325
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G |
KCNB2 |
potassium voltage-gated channel subfamily B member 2 |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KCNB2 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of KCNB2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 8:72,537,225...72,938,349
Ensembl chr 8:72,537,225...72,938,349
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G |
LIF |
LIF interleukin 6 family cytokine |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of LIF mRNA |
CTD |
PMID:30116771 |
|
NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
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G |
MFSD6 |
major facilitator superfamily domain containing 6 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of MFSD6 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:190,407,576...190,502,314
Ensembl chr 2:190,408,355...190,509,205
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G |
MSH2 |
mutS homolog 2 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of MSH2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146
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G |
NFIX |
nuclear factor I X |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of NFIX mRNA |
CTD |
PMID:30116771 |
|
NCBI chr19:12,995,475...13,098,796
Ensembl chr19:12,995,475...13,098,796
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
affects expression |
EXP |
2,4-dinitrobenzenesulfonic acid affects the expression of NFKB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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G |
NT5E |
5'-nucleotidase ecto |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of NT5E mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of NT5E mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791
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G |
ODC1 |
ornithine decarboxylase 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of ODC1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
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G |
OPRK1 |
opioid receptor kappa 1 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of OPRK1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637
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|
G |
PDE4D |
phosphodiesterase 4D |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PDE4D mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of PDE4D mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
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G |
PIK3C2A |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of PIK3C2A mRNA |
CTD |
PMID:30116771 |
|
NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986
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G |
PSMB8 |
proteasome 20S subunit beta 8 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
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G |
PTGER4 |
prostaglandin E receptor 4 |
multiple interactions decreases expression |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PTGER4 mRNA 2,4-dinitrobenzenesulfonic acid results in decreased expression of PTGER4 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
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G |
RPS15A |
ribosomal protein S15a |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of RPS15A mRNA |
CTD |
PMID:30116771 |
|
NCBI chr16:18,781,295...18,790,334
Ensembl chr16:18,781,295...18,790,383
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G |
SGCD |
sarcoglycan delta |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of SGCD mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 5:155,727,832...156,767,788
Ensembl chr 5:155,870,344...156,767,788
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G |
SLC9A1 |
solute carrier family 9 member A1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of SLC9A1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
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G |
TAC1 |
tachykinin precursor 1 |
increases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA] |
CTD |
PMID:30116771 |
|
NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
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G |
TACR2 |
tachykinin receptor 2 |
multiple interactions |
ISO |
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in decreased expression of TACR2 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918
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G |
TAF1B |
TATA-box binding protein associated factor, RNA polymerase I subunit B |
decreases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of TAF1B mRNA [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of TAF1B mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 2:9,843,442...9,934,416
Ensembl chr 2:9,843,443...9,934,416
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G |
TAPBPL |
TAP binding protein like |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of TAPBPL mRNA |
CTD |
PMID:30116771 |
|
NCBI chr12:6,451,649...6,472,006
Ensembl chr12:6,451,690...6,466,517
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G |
THBS1 |
thrombospondin 1 |
increases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of THBS1 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
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G |
TNF |
tumor necrosis factor |
increases expression |
EXP |
2,4-dinitrobenzenesulfonic acid results in increased expression of TNF mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TRIM62 |
tripartite motif containing 62 |
decreases expression |
ISO |
2,4-dinitrobenzenesulfonic acid results in decreased expression of TRIM62 mRNA |
CTD |
PMID:30116771 |
|
NCBI chr 1:33,145,399...33,182,043
Ensembl chr 1:33,145,399...33,182,059
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G |
VTI1A |
vesicle transport through interaction with t-SNAREs 1A |
increases expression multiple interactions |
ISO |
2,4-dinitrobenzenesulfonic acid results in increased expression of VTI1A mRNA [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of VTI1A mRNA |
CTD |
PMID:30116771 |
|
NCBI chr10:112,446,988...112,855,368
Ensembl chr10:112,446,998...112,818,744
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G |
CAT |
catalase |
decreases activity |
ISO |
metanil yellow results in decreased activity of CAT protein |
CTD |
PMID:26494366 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCNB1 |
cyclin B1 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein |
CTD |
PMID:12616621 |
|
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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G |
CCND1 |
cyclin D1 |
multiple interactions increases expression |
ISO |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein] metanil yellow results in increased expression of CCND1 protein |
CTD |
PMID:10906429 PMID:12616621 |
|
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCNE1 |
cyclin E1 |
multiple interactions increases expression |
ISO |
metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein] metanil yellow results in increased expression of CCNE1 protein |
CTD |
PMID:10906429 |
|
NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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G |
CDK1 |
cyclin dependent kinase 1 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 protein |
CTD |
PMID:12616621 |
|
NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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|
G |
CDK4 |
cyclin dependent kinase 4 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein |
CTD |
PMID:12616621 |
|
NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
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|
G |
FSHB |
follicle stimulating hormone subunit beta |
decreases expression |
ISO |
metanil yellow results in decreased expression of FSHB |
CTD |
PMID:26494366 |
|
NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
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|
G |
GSR |
glutathione-disulfide reductase |
decreases activity |
ISO |
metanil yellow results in decreased activity of GSR protein |
CTD |
PMID:26494366 |
|
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
LHB |
luteinizing hormone subunit beta |
decreases expression |
ISO |
metanil yellow results in decreased expression of LHB |
CTD |
PMID:26494366 |
|
NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
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G |
PCNA |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of PCNA protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of PCNA protein] metanil yellow results in increased expression of PCNA protein |
CTD |
PMID:10906429 PMID:11831363 PMID:12616621 |
|
NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
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|
|
G |
AICDA |
activation induced cytidine deaminase |
increases response to substance multiple interactions |
EXP ISO |
AICDA results in increased susceptibility to 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein |
CTD |
PMID:23589568 |
|
NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
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|
G |
ALB |
albumin |
decreases uptake |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased uptake of ALB protein |
CTD |
PMID:16313995 |
|
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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G |
ANO6 |
anoctamin 6 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of ANO6 protein |
CTD |
PMID:24478309 |
|
NCBI chr12:45,216,095...45,440,404
Ensembl chr12:45,215,987...45,482,280
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|
G |
ATF4 |
activating transcription factor 4 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 protein] |
CTD |
PMID:27638049 |
|
NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
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|
G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; [Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein |
CTD |
PMID:18590702 PMID:28343033 |
|
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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|
G |
CASP9 |
caspase 9 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] |
CTD |
PMID:14766669 PMID:28343033 |
|
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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|
G |
CFTR |
CF transmembrane conductance regulator |
multiple interactions decreases activity |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CFTR protein |
CTD |
PMID:15131065 PMID:16038730 |
|
NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
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|
G |
CLCN3 |
chloride voltage-gated channel 3 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLCN3 protein |
CTD |
PMID:17699636 |
|
NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673
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|
G |
CLCNKA |
chloride voltage-gated channel Ka |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKA protein |
CTD |
PMID:15167890 |
|
NCBI chr 1:16,022,036...16,034,050
Ensembl chr 1:16,018,875...16,034,050
|
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G |
CLCNKB |
chloride voltage-gated channel Kb |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKB protein |
CTD |
PMID:15167890 |
|
NCBI chr 1:16,043,782...16,057,326
Ensembl chr 1:16,040,252...16,057,311
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G |
CLIC1 |
chloride intracellular channel 1 |
multiple interactions |
EXP |
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine |
CTD |
PMID:18590702 |
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NCBI chr 6:31,730,581...31,737,318
Ensembl chr 6:31,730,581...31,739,763
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions |
ISO EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of DDIT3 protein] |
CTD |
PMID:27638049 PMID:29421517 |
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of EIF2AK3 protein modified form] |
CTD |
PMID:27638049 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:27638049 |
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NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of HSPA5 protein] |
CTD |
PMID:29421517 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
IFNG |
interferon gamma |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] |
CTD |
PMID:11907163 |
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IL12B |
interleukin 12B |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] |
CTD |
PMID:11907163 |
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NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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G |
IL1B |
interleukin 1 beta |
affects secretion multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid affects the secretion of IL1B protein 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of IL1B mRNA] |
CTD |
PMID:15578659 PMID:27461142 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
ITPR1 |
inositol 1,4,5-trisphosphate receptor type 1 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ITPR1 protein modified form] |
CTD |
PMID:27638049 |
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NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein] |
CTD |
PMID:19815690 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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G |
MAPK9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein] |
CTD |
PMID:19815690 |
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NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
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G |
PANX1 |
pannexin 1 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of PANX1 protein |
CTD |
PMID:19023039 |
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NCBI chr11:94,128,841...94,181,968
Ensembl chr11:94,128,841...94,181,968
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form] |
CTD |
PMID:28343033 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PDCD6IP |
programmed cell death 6 interacting protein |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in decreased expression of PDCD6IP protein] |
CTD |
PMID:29421517 |
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NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707
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G |
RAD51 |
RAD51 recombinase |
decreases activity multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein |
CTD |
PMID:23589568 |
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NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
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G |
RARA |
retinoic acid receptor alpha |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased degradation of RARA protein] |
CTD |
PMID:17018029 |
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NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
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G |
SCT |
secretin |
decreases activity |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SCT protein |
CTD |
PMID:10880878 |
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NCBI chr11:626,309...627,181
Ensembl chr11:626,309...627,181
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G |
SLC12A7 |
solute carrier family 12 member 7 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC12A7 protein |
CTD |
PMID:10913127 |
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NCBI chr 5:1,050,384...1,155,899
Ensembl chr 5:1,050,384...1,112,063
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G |
SLC19A1 |
solute carrier family 19 member 1 |
multiple interactions |
EXP |
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC19A1 protein] which results in decreased uptake of Folic Acid |
CTD |
PMID:17034785 |
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NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365
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G |
SLC22A6 |
solute carrier family 22 member 6 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] |
CTD |
PMID:12472777 |
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NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967
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G |
SLC46A1 |
solute carrier family 46 member 1 |
multiple interactions decreases activity |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC46A1 protein |
CTD |
PMID:17475902 |
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NCBI chr17:28,394,642...28,406,592
Ensembl chr17:28,394,642...28,407,197
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G |
SLC4A1 |
solute carrier family 4 member 1 (Diego blood group) |
multiple interactions affects binding |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid binds to SLC4A1 protein |
CTD |
PMID:2511191 |
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NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141
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G |
SLC4A2 |
solute carrier family 4 member 2 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A2 protein results in increased uptake of Benzoic Acid] |
CTD |
PMID:9563070 |
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NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526
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G |
SLC4A4 |
solute carrier family 4 member 4 |
decreases activity |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC4A4 protein |
CTD |
PMID:17325238 |
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NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087
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G |
SLC5A5 |
solute carrier family 5 member 5 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] |
CTD |
PMID:12541134 |
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NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174
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G |
SQSTM1 |
sequestosome 1 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of SQSTM1 protein] |
CTD |
PMID:29421517 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
ISO |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of TGFB1 mRNA] |
CTD |
PMID:27461142 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TP53 |
tumor protein p53 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] |
CTD |
PMID:10951577 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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G |
VDAC1 |
voltage dependent anion channel 1 |
multiple interactions |
ISO EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Staurosporine promotes the reaction [VDAC1 protein binds to VDAC1 protein]] 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC1 protein binds to VDAC1 protein]] |
CTD |
PMID:20937774 PMID:28343033 |
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NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
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G |
VDAC2 |
voltage dependent anion channel 2 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC2 protein binds to VDAC2 protein]] |
CTD |
PMID:29229420 |
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NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
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G |
SLC4A1 |
solute carrier family 4 member 1 (Diego blood group) |
multiple interactions |
EXP |
4,4'-dinitro-2,2'-stilbenedisulfonic acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides] |
CTD |
PMID:2511191 |
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NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141
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G |
AVP |
arginine vasopressin |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] |
CTD |
PMID:11102496 |
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NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
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G |
FN1 |
fibronectin 1 |
decreases expression |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid results in decreased expression of FN1 mRNA |
CTD |
PMID:18210741 |
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NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
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G |
H2AX |
H2A.X variant histone |
multiple interactions |
EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] |
CTD |
PMID:32941855 |
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NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
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G |
IL6 |
interleukin 6 |
multiple interactions |
EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein] |
CTD |
PMID:24793913 |
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
NOX1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] |
CTD |
PMID:24912985 |
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NCBI chr X:100,843,324...100,874,359
Ensembl chr X:100,843,324...100,874,359
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G |
OXT |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] |
CTD |
PMID:11102496 |
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NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517
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G |
P2RX7 |
purinergic receptor P2X 7 |
multiple interactions |
ISO EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein] |
CTD |
PMID:21638035 PMID:31263019 |
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NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] |
CTD |
PMID:22253048 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
TP53BP1 |
tumor protein p53 binding protein 1 |
multiple interactions |
EXP |
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] |
CTD |
PMID:32941855 |
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NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728
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G |
TP53 |
tumor protein p53 |
affects activity |
EXP |
7-amino-4-hydroxy-2-naphthalenesulfonic acid affects the activity of TP53 protein; 7-amino-4-hydroxy-2-naphthalenesulfonic acid metabolite affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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G |
AMBP |
alpha-1-microglobulin/bikunin precursor |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to AMBP protein |
CTD |
PMID:16461020 |
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NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
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G |
APOD |
apolipoprotein D |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to APOD protein |
CTD |
PMID:16461020 |
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NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033
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G |
C8G |
complement C8 gamma chain |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to C8G protein |
CTD |
PMID:16461020 |
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NCBI chr 9:136,945,243...136,946,975
Ensembl chr 9:136,945,185...136,946,975
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G |
GSTA1 |
glutathione S-transferase alpha 1 |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to GSTA1 protein |
CTD |
PMID:14690442 |
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NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
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G |
LCN1 |
lipocalin 1 |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to LCN1 protein |
CTD |
PMID:16461020 |
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NCBI chr 9:135,521,440...135,526,540
Ensembl chr 9:135,521,438...135,526,540
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G |
LCN2 |
lipocalin 2 |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to LCN2 protein |
CTD |
PMID:16461020 |
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NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
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G |
OBP2A |
odorant binding protein 2A |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to OBP2A protein |
CTD |
PMID:16461020 |
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NCBI chr 9:135,546,126...135,549,969
Ensembl chr 9:135,546,126...135,549,969
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G |
ORM1 |
orosomucoid 1 |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to ORM1 protein |
CTD |
PMID:16461020 |
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NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
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G |
PAEP |
progestagen associated endometrial protein |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to PAEP protein |
CTD |
PMID:16461020 |
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NCBI chr 9:135,561,756...135,566,955
Ensembl chr 9:135,561,756...135,566,955
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G |
PTGDS |
prostaglandin D2 synthase |
affects binding |
EXP |
1-anilino-8-naphthalenesulfonate binds to PTGDS protein |
CTD |
PMID:16461020 |
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NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
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G |
TTR |
transthyretin |
affects binding multiple interactions |
EXP |
1-anilino-8-naphthalenesulfonate binds to TTR protein 3,3'-dichlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 3,4-dichlorinated biphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 4-chlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; Thyroxine inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein] |
CTD |
PMID:23584369 |
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NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833
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G |
ACTB |
actin beta |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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G |
ARHGDIA |
Rho GDP dissociation inhibitor alpha |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA |
CTD |
PMID:15477007 |
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NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,719...81,871,378
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
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G |
ATOX1 |
antioxidant 1 copper chaperone |
multiple interactions |
ISO |
ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 mRNA]; ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] |
CTD |
PMID:20194531 |
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NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532
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G |
ATP7A |
ATPase copper transporting alpha |
multiple interactions |
EXP |
[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] |
CTD |
PMID:11092760 PMID:21242307 |
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NCBI chr X:77,910,693...78,050,395
Ensembl chr X:77,910,690...78,050,395
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G |
ATP7B |
ATPase copper transporting beta |
multiple interactions |
EXP |
[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein] |
CTD |
PMID:21242307 |
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NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression |
EXP |
bathocuproine sulfonate results in decreased expression of BCL2 protein |
CTD |
PMID:24614111 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2A1 |
BCL2 related protein A1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]] |
CTD |
PMID:15477007 |
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NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
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G |
CASP3 |
caspase 3 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein] |
CTD |
PMID:10941151 PMID:11239917 PMID:18056745 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP8 |
caspase 8 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]] |
CTD |
PMID:15477007 |
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NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]] |
CTD |
PMID:11006087 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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G |
CCL3L1 |
C-C motif chemokine ligand 3 like 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3L1 mRNA] |
CTD |
PMID:15477007 |
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Ensembl chr17:36,194,869...36,196,758
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G |
CCT5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]] |
CTD |
PMID:15477007 |
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NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
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G |
CD200 |
CD200 molecule |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 3:112,332,573...112,362,812
Ensembl chr 3:112,332,235...112,363,181
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G |
CD44 |
CD44 molecule (IN blood group) |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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G |
CDH17 |
cadherin 17 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
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G |
CLU |
clusterin |
multiple interactions |
EXP |
[Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein] |
CTD |
PMID:21242307 |
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NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
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G |
CNTNAP1 |
contactin associated protein 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr17:42,682,531...42,699,993
Ensembl chr17:42,682,531...42,699,993
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G |
COMT |
catechol-O-methyltransferase |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] |
CTD |
PMID:15477007 |
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NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
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G |
CP |
ceruloplasmin |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein] |
CTD |
PMID:17032174 |
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NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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G |
CPSF1 |
cleavage and polyadenylation specific factor 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:144,393,231...144,409,335
Ensembl chr 8:144,393,229...144,409,335
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G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CREM |
cAMP responsive element modulator |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
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G |
CUL5 |
cullin 5 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:108,008,898...108,107,761
Ensembl chr11:108,008,898...108,107,761
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G |
CYCS |
cytochrome c, somatic |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which affects the localization of CYCS protein] |
CTD |
PMID:18056745 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
DNAJB1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,513,789...14,560,391
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G |
DUSP4 |
dual specificity phosphatase 4 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]] |
CTD |
PMID:15477007 |
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NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684
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G |
EGR2 |
early growth response 2 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
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G |
EGR3 |
early growth response 3 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
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G |
FASN |
fatty acid synthase |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of FASN mRNA] |
CTD |
PMID:24170205 |
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NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FGF2 |
fibroblast growth factor 2 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:22842628 |
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NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]] |
CTD |
PMID:15477007 PMID:17032174 |
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NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
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G |
FYB1 |
FYN binding protein 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:39,105,252...39,274,528
Ensembl chr 5:39,105,252...39,274,528
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G |
GFRA2 |
GDNF family receptor alpha 2 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357
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G |
GNAS |
GNAS complex locus |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA |
CTD |
PMID:15477007 |
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NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
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G |
GNLY |
granulysin |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNLY mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852
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G |
GTF2H2C |
GTF2H2 family member C |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA |
CTD |
PMID:15477007 |
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NCBI chr 5:69,560,191...69,595,221
Ensembl chr 5:69,560,191...69,595,221 Ensembl chr 5:69,560,191...69,595,221
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G |
HADHA |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
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G |
HCK |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] |
CTD |
PMID:15477007 |
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NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
EXP |
[Penicillamine co-treated with bathocuproine sulfonate] results in increased expression of HMOX1 protein |
CTD |
PMID:21242307 |
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HNRNPUL1 |
heterogeneous nuclear ribonucleoprotein U like 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr19:41,262,557...41,307,787
Ensembl chr19:41,262,496...41,307,787
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G |
HPX |
hemopexin |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] affects the localization of MTF1 protein]; bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] results in increased expression of MTF1 mRNA]; bathocuproine sulfonate inhibits the reaction [[Heme co-treated with HPX protein] affects the localization of MTF1 protein] |
CTD |
PMID:11213479 |
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NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617
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G |
HSPA8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]] |
CTD |
PMID:15477007 |
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NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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G |
HYAL3 |
hyaluronidase 3 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 3:50,292,832...50,299,405
Ensembl chr 3:50,292,831...50,299,405
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G |
IL2 |
interleukin 2 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]] |
CTD |
PMID:15477007 |
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NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
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G |
IL2RA |
interleukin 2 receptor subunit alpha |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] |
CTD |
PMID:23134680 |
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NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
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G |
IL2RB |
interleukin 2 receptor subunit beta |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]] |
CTD |
PMID:15477007 PMID:17032174 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
LCP1 |
lymphocyte cytosolic protein 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871
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G |
LDLR |
low density lipoprotein receptor |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of LDLR mRNA] |
CTD |
PMID:24170205 |
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NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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G |
LTBP4 |
latent transform |