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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:aryl group
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Accession:CHEBI:33338 term browser browse the term
Definition:A group derived from an arene by removal of a hydrogen atom from a ring carbon atom.
Synonyms:exact_synonym: aryl groups
 related_synonym: Arylgruppe;   groupe aryle;   grupos arilo


show annotations for term's descendants           Sort by:
2,4,6-trinitrobenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 protein CTD PMID:12044520 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA] 		CTD PMID:18200517 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein CTD PMID:12044520 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Actb actin, beta increases expression
decreases expression 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of ACTB mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of ACTB mRNA 		CTD PMID:12163651 PMID:17982090 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Adm2 adrenomedullin 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ADM2 mRNA CTD PMID:21808981 NCBI chr 7:122,272,808...122,274,594
Ensembl chr 7:122,272,808...122,274,594 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases abundance
increases expression 		EXP cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Ager protein in rat colon 		CTD
RGD		 PMID:33412153 PMID:33522063 PMID:29572553 RGD:152995414 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AGR2 mRNA CTD PMID:17982090 NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:21131560 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AK3 mRNA CTD PMID:17982090 NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183 		JBrowse link
G Akap6 A-kinase anchoring protein 6 multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA] CTD PMID:18200517 NCBI chr 6:75,919,350...76,359,667
Ensembl chr 6:75,919,513...76,355,036 		JBrowse link
G Akap9 A-kinase anchoring protein 9 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AKAP9 mRNA CTD PMID:17982090 NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA CTD PMID:25724174 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Alb albumin increases secretion EXP Trinitrobenzenesulfonic Acid results in increased secretion of ALB protein CTD PMID:23307618 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ALDH1A3 mRNA CTD PMID:17982090 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777 		JBrowse link
G Alpi alkaline phosphatase, intestinal increases activity
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein
Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein] 		CTD PMID:15867298 NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780 		JBrowse link
G Amy2a5 amylase 2a5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AMY2A5 mRNA CTD PMID:17982090 NCBI chr 2:203,949,578...203,958,111 JBrowse link
G Anxa1 annexin A1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA CTD PMID:17982090 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Anxa8 annexin A8 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ANXA8 mRNA CTD PMID:17982090 NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,403,353...9,418,310 		JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA CTD PMID:17982090 NCBI chr17:89,849,474...89,941,099
Ensembl chr17:89,671,716...89,941,089 		JBrowse link
G Apob apolipoprotein B decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA CTD PMID:17982090 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of AQP3 mRNA CTD PMID:15140218 NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685 		JBrowse link
G Aqp4 aquaporin 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of AQP4 mRNA CTD PMID:23537331 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098 		JBrowse link
G Arfip1 ARF interacting protein 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ARFIP1 mRNA CTD PMID:23537331 NCBI chr 2:172,141,862...172,224,464
Ensembl chr 2:172,141,859...172,221,280 		JBrowse link
G Arg1 arginase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ARG1 mRNA CTD PMID:17982090 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Arg2 arginase 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA CTD PMID:17982090 NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA] CTD PMID:18200517 NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA] CTD PMID:18200517 NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068 		JBrowse link
G Arl4d ARF like GTPase 4D increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ARL4D mRNA CTD PMID:23537331 NCBI chr10:87,092,276...87,103,079
Ensembl chr10:87,077,523...87,106,199 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions
increases expression 		EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein 		CTD PMID:24637189 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Atoh1 atonal bHLH transcription factor 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of ATOH1 mRNA CTD PMID:17982090 NCBI chr 4:95,241,933...95,244,028
Ensembl chr 4:95,241,933...95,244,019 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 protein CTD PMID:17131044 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ATP4A mRNA CTD PMID:17982090 NCBI chr 1:95,089,122...95,102,277
Ensembl chr 1:95,089,122...95,102,277 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression 		EXP Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAK1 mRNA] CTD PMID:15502641 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of BASP1 mRNA CTD PMID:17982090 NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:77,546,092...77,597,178 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		EXP
ISO 		dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BAX protein
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BAX protein] 		CTD PMID:15502641 PMID:22427801 PMID:24831514 PMID:31428839 PMID:33412153 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases abundance
increases expression
decreases expression 		EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Losartan promotes the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]
2,4,6-trinitrobenzenesulfonic acid decreases abundance of Bcl-2 protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein
Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein 		CTD
RGD		 PMID:15502641 PMID:24637189 PMID:24831514 PMID:31428839 PMID:33412153 More... RGD:152995414 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of BCL2A1B mRNA CTD PMID:17982090 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890 		JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions
increases expression 		ISO [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein]
Trinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein 		CTD PMID:22427801 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA] CTD PMID:18200517 NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368 		JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression 		EXP dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] CTD PMID:30503585 PMID:33412153 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP protein CTD PMID:23747339 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Bgn biglycan increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA] 		CTD PMID:18200517 NCBI chr  X:156,348,633...156,360,797
Ensembl chr  X:156,348,615...156,360,799 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of BPNT2 mRNA CTD PMID:17982090 NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126 		JBrowse link
G C1qb complement C1q B chain multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840 		JBrowse link
G C1qc complement C1q C chain increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of C1QC mRNA CTD PMID:17982090 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468 		JBrowse link
G C3 complement C3 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G C4b complement C4B increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA] 		CTD PMID:18200517 NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289 		JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CAR3 mRNA CTD PMID:17982090 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Cab39 calcium binding protein 39 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CAB39 mRNA CTD PMID:12163651 NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C protein CTD PMID:23537331 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E protein CTD PMID:23537331 NCBI chr13:69,125,048...69,613,795
Ensembl chr13:69,132,305...69,612,983 		JBrowse link
G Calcb calcitonin-related polypeptide, beta decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CALCB mRNA CTD PMID:21808981 NCBI chr 1:178,399,634...178,404,654
Ensembl chr 1:178,399,785...178,404,654 		JBrowse link
G Calcrl calcitonin receptor like receptor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CALCRL mRNA CTD PMID:21808981 NCBI chr 3:89,835,071...89,932,616
Ensembl chr 3:89,835,077...89,887,350 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CAMK2B mRNA CTD PMID:23537331 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA] CTD PMID:18200517 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672 		JBrowse link
G Capn1 calpain 1 multiple interactions
increases expression 		EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] CTD PMID:30503585 NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445 		JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression 		EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein CTD PMID:30365937 PMID:30503585 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage 		EXP Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression 		ISO
EXP 		D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein
Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein 		CTD PMID:22427801 PMID:24831514 PMID:26165751 PMID:30503585 PMID:33412153 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp4 caspase 4 multiple interactions EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein CTD PMID:30365937 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727 		JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression 		EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] CTD PMID:30503585 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form] 		CTD PMID:30503585 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase increases expression
multiple interactions
decreases expression 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of CAT mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA] 		CTD PMID:17982090 PMID:30503585 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein
Trinitrobenzenesulfonic Acid results in increased secretion of CCL2 protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein]
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA] 		CTD PMID:17449585 PMID:17982090 PMID:23307618 PMID:23596210 PMID:30503585 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression 		ISO [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein] CTD PMID:21599020 PMID:23596210 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
increases expression 		ISO icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL4 protein] CTD PMID:23596210 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA CTD PMID:17982090 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression 		ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions
decreases expression
increases expression 		ISO
EXP 		NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of CCN4 mRNA 		CTD PMID:19238344 PMID:23537331 NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:100,534,505...100,563,094 		JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA CTD PMID:17982090 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCR2 mRNA CTD PMID:17982090 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCR5 mRNA CTD PMID:15973123 PMID:17982090 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA CTD PMID:17982090 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CD3G mRNA CTD PMID:23537331 NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918 		JBrowse link
G Cd44 CD44 molecule multiple interactions
increases expression 		ISO seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein] CTD PMID:11717450 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cd47 Cd47 molecule multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA] CTD PMID:18200517 NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272 		JBrowse link
G Cd53 Cd53 molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD53 mRNA CTD PMID:17982090 NCBI chr 2:197,040,369...197,087,925
Ensembl chr 2:197,040,369...197,218,593 		JBrowse link
G Cd79a CD79a molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNA CTD PMID:17982090 NCBI chr 1:89,621,460...89,625,813
Ensembl chr 1:89,621,460...89,625,812 		JBrowse link
G Cdh17 cadherin 17 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CDH17 mRNA CTD PMID:12163651 NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226 		JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CDR2 mRNA CTD PMID:17982090 NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CEACAM10 mRNA CTD PMID:17982090 NCBI chr 1:89,504,555...89,510,831
Ensembl chr 1:89,504,555...89,510,831 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA] CTD PMID:18200517 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CEL mRNA CTD PMID:17982090 NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019 		JBrowse link
G Cela2a chymotrypsin like elastase 2A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CELA2A mRNA CTD PMID:17982090 NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:159,409,899...159,426,208 		JBrowse link
G Ces1d carboxylesterase 1D increases expression
decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA] 		CTD PMID:18200517 PMID:19524605 PMID:22609641 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA] 		CTD PMID:17982090 PMID:18200517 NCBI chr19:49,902,312...49,910,484 JBrowse link
G Cfd complement factor D decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CFD mRNA CTD PMID:17982090 NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572 		JBrowse link
G Cfh complement factor H increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CFH mRNA CTD PMID:17982090 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CHI3L1 mRNA CTD PMID:17982090 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Chkb choline kinase beta decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CHKB mRNA CTD PMID:17982090 NCBI chr 7:122,380,592...122,385,102
Ensembl chr 7:122,380,594...122,383,949 		JBrowse link
G Clca1 chloride channel accessory 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CLCA1 mRNA CTD PMID:17982090 NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714 		JBrowse link
G Clca4 chloride channel accessory 4 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA] CTD PMID:18200517 NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:236,544,201...236,563,435 		JBrowse link
G Cldn1 claudin 1 multiple interactions
decreases expression 		ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] CTD PMID:22849695 PMID:39237074 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529 		JBrowse link
G Cldn2 claudin 2 multiple interactions
decreases expression 		EXP oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of CLDN2 protein 		CTD PMID:35290143 NCBI chr  X:108,248,383...108,258,847
Ensembl chr  X:108,237,676...108,262,377 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression 		ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA] CTD PMID:17982090 PMID:25740948 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions
increases expression 		ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA] CTD PMID:17982090 PMID:18200517 PMID:20889569 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA] CTD PMID:18200517 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520 		JBrowse link
G Col5a1 collagen type V alpha 1 chain multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA] CTD PMID:18200517 NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020 		JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA] CTD PMID:18200517 NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150 		JBrowse link
G Cort cortistatin increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CORT protein CTD PMID:11959675 NCBI chr 5:164,843,682...164,845,796 JBrowse link
G Crh corticotropin releasing hormone decreases expression
increases expression 		EXP Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA
Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA 		CTD PMID:11668029 PMID:11959675 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CRHR1 mRNA CTD PMID:15178552 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466 		JBrowse link
G Crisp3 cysteine-rich secretory protein 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CRISP3 mRNA CTD PMID:17982090 NCBI chr 9:27,928,591...27,969,205
Ensembl chr 9:27,895,536...27,969,198 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA] CTD PMID:18200517 NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CSF3 protein CTD PMID:23596210 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression 		EXP geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein 		CTD PMID:26165751 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctrb1 chymotrypsinogen B1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CTRB1 mRNA CTD PMID:17982090 NCBI chr19:56,562,220...56,566,978
Ensembl chr19:56,562,220...56,566,978 		JBrowse link
G Ctsc cathepsin C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA CTD PMID:17982090 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CX3CL1 mRNA CTD PMID:15973123 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL10 protein CTD PMID:23596210 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA CTD PMID:15973123 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL13 mRNA CTD PMID:15973123 NCBI chr14:13,912,858...13,917,920
Ensembl chr14:13,912,858...13,917,920 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL14 mRNA CTD PMID:15973123 NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA] CTD PMID:17375199 PMID:18200517 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression 		ISO icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein 		CTD PMID:17982090 PMID:23596210 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL5 mRNA CTD PMID:17982090 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL9 mRNA CTD PMID:17982090 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCR2 mRNA CTD PMID:15973123 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression 		EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein 		CTD PMID:24831514 PMID:30503585 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein CTD PMID:18079364 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein CTD PMID:18079364 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein CTD PMID:18079364 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein CTD PMID:18079364 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CYP3A13 mRNA CTD PMID:17982090 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Dcp2 decapping mRNA 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of DCP2 mRNA CTD PMID:12163651 NCBI chr18:37,001,615...37,037,949
Ensembl chr18:37,001,615...37,049,939 		JBrowse link
G Defa5 defensin alpha 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of DEFA5 mRNA CTD PMID:17982090 NCBI chr16:77,044,994...77,047,318
Ensembl chr16:77,044,994...77,047,318 		JBrowse link
G Defb2 defensin beta 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of DEFB2 mRNA CTD PMID:19998380 NCBI chr16:76,934,341...76,948,284
Ensembl chr16:76,934,337...76,948,299 		JBrowse link
G Dnaaf5 dynein, axonemal, assembly factor 5 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of DNAAF5 mRNA CTD PMID:17982090 NCBI chr12:20,567,482...20,606,600
Ensembl chr12:20,531,267...20,607,607 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of DPP4 mRNA CTD PMID:12163651 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422 		JBrowse link
G Dsg2 desmoglein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of DSG2 mRNA CTD PMID:17982090 NCBI chr18:12,121,287...12,179,590
Ensembl chr18:12,121,181...12,179,590 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA CTD PMID:12163651 NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of EIF4A2 mRNA CTD PMID:12163651 NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of EIF4EBP2 mRNA CTD PMID:17982090 NCBI chr20:29,922,260...29,942,922
Ensembl chr20:29,922,260...29,942,922 		JBrowse link
G Emb embigin multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA] CTD PMID:18200517 NCBI chr 2:50,803,468...50,858,001
Ensembl chr 2:50,801,973...50,862,920 		JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of EPHB3 mRNA CTD PMID:17982090 NCBI chr11:93,345,098...93,363,775
Ensembl chr11:93,345,098...93,363,775 		JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of FABP2 mRNA CTD PMID:17982090 NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:213,724,629...213,728,686 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression 		ISO D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of FASL protein]
Trinitrobenzenesulfonic Acid results in increased expression of FASL protein 		CTD PMID:22427801 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fbln2 fibulin 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA] CTD PMID:18200517 NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FBXL2 mRNA CTD PMID:12163651 NCBI chr 8:122,794,870...122,843,265
Ensembl chr 8:122,794,870...122,854,798 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of FCGR2B mRNA CTD PMID:19524605 NCBI chr13:85,725,897...85,740,517
Ensembl chr13:85,725,897...85,740,517 		JBrowse link
G Fcgr3a Fc gamma receptor 3A multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA] CTD PMID:18200517 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651 		JBrowse link
G Fgf17 fibroblast growth factor 17 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of FGF17 mRNA CTD PMID:23537331 NCBI chr15:52,118,141...52,132,083
Ensembl chr15:52,121,191...52,132,016 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FGFR3 mRNA CTD PMID:23537331 NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA] CTD PMID:18200517 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FOS mRNA CTD PMID:15178552 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fpr3 formyl peptide receptor 3 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA] 		CTD PMID:18200517 NCBI chr 1:67,557,464...67,566,509
Ensembl chr 1:67,518,199...67,566,519 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA] CTD PMID:18200517 NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126 		JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of FXYD5 mRNA CTD PMID:23537331 NCBI chr 1:95,395,327...95,404,722
Ensembl chr 1:95,395,146...95,405,364 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GABBR1 mRNA CTD PMID:17982090 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,469,779...1,498,607 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GBP2 mRNA CTD PMID:17982090 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810 		JBrowse link
G Gbp4 guanylate binding protein 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GBP3 mRNA CTD PMID:17982090 NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:233,978,486...233,992,120 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GCH1 mRNA CTD PMID:17982090 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Trinitrobenzenesulfonic Acid co-treated with Ethanol] results in increased expression of GCLC mRNA CTD PMID:10830784 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gda guanine deaminase multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA] CTD PMID:18200517 NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA CTD PMID:17982090 NCBI chr 1:190,804,053...190,813,609
Ensembl chr 1:190,803,993...190,813,606 		JBrowse link
G Ggta1 glycoprotein alpha-galactosyltransferase 1 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA] 		CTD PMID:18200517 NCBI chr 3:39,130,466...39,208,652
Ensembl chr 3:39,130,467...39,206,870 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
decreases expression 		EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] CTD PMID:30503585 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA] CTD PMID:18200517 NCBI chr16:71,563,562...71,576,446
Ensembl chr16:71,563,534...71,570,468 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] 		CTD PMID:30503585 NCBI chr19:9,180,428...9,206,113
Ensembl chr19:9,180,431...9,206,111 		JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of GPX2 mRNA CTD PMID:31669340 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862 		JBrowse link
G Grb10 growth factor receptor bound protein 10 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA] CTD PMID:18200517 NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA] 		CTD PMID:18200517 NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of GRIA2 mRNA CTD PMID:23537331 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] 		CTD PMID:26165751 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsn gelsolin multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
decreases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein
Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein]; 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA] 		CTD PMID:31669340 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNA CTD PMID:17982090 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of GSTT1 mRNA CTD PMID:31669340 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
increases secretion 		EXP Trinitrobenzenesulfonic Acid results in increased expression of HAVCR1 mRNA
Trinitrobenzenesulfonic Acid results in increased secretion of HAVCR1 protein 		CTD PMID:23307618 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HBB-B2 mRNA CTD PMID:17982090 NCBI chr 1:167,655,583...167,656,963 JBrowse link
G Hebp2 heme binding protein 2 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA] 		CTD PMID:18200517 NCBI chr 1:15,014,729...15,021,523
Ensembl chr 1:15,014,729...15,021,523 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases abundance
increases expression 		EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Hmgb1 protein in rat colon 		CTD
RGD		 PMID:33412153 PMID:29572553 RGD:152995414 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HMGCR mRNA CTD PMID:17982090 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression 		EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Heme promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein 		CTD PMID:17292349 PMID:25469038 PMID:30503585 PMID:33412153 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hoxd13 homeo box D13 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HOXD13 mRNA CTD PMID:17982090 NCBI chr 3:79,978,077...79,981,393
Ensembl chr 3:79,978,076...79,981,393 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase affects expression EXP Trinitrobenzenesulfonic Acid affects the expression of HPGD mRNA CTD PMID:25526689 NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831 		JBrowse link
G Hrh4 histamine receptor H4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HRH4 mRNA CTD PMID:24561612 NCBI chr18:4,440,977...4,457,132
Ensembl chr18:4,440,977...4,457,132 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA CTD PMID:21513799 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein] 		CTD PMID:30503585 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspb7 heat shock protein family B (small) member 7 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA] CTD PMID:18200517 NCBI chr 5:159,010,759...159,014,245
Ensembl chr 5:159,010,629...159,014,243 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA CTD PMID:23537331 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA CTD PMID:23537331 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases abundance
increases expression 		ISO
EXP 		Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Icam-1 protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA] 		CTD
RGD		 PMID:18200517 PMID:22029500 PMID:26165751 PMID:30503585 PMID:31428839 More... RGD:152995414 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IDO1 mRNA CTD PMID:17982090 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of IFI27 mRNA CTD PMID:17982090 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781 		JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase multiple interactions EXP [topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA CTD PMID:21849664 NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,709,563...18,715,711 		JBrowse link
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFIT1 mRNA CTD PMID:17982090 NCBI chr 1:241,565,197...241,567,262
Ensembl chr 1:241,543,184...241,568,148 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFIT2 mRNA CTD PMID:17982090 NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFITM3 mRNA CTD PMID:17982090 NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:205,481,168...205,547,920 		JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFNB1 mRNA CTD PMID:17375199 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
decreases expression 		EXP
ISO 		bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IFNG mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IFNG; Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein] 		CTD PMID:11717450 PMID:15973123 PMID:16782535 PMID:16867261 PMID:19285099 More... NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression 		ISO
EXP 		6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein 		CTD PMID:18200517 PMID:20889569 PMID:24782617 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA] CTD PMID:18200517 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases abundance
decreases secretion
increases expression
decreases expression 		EXP
ISO 		[iberogast analog co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; [iberogast co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]
2,4,6-trinitrobenzenesulfonic acid decreases abundance of IL-10 protein in rat colon
Trinitrobenzenesulfonic Acid results in decreased secretion of IL10 protein
Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein
Trinitrobenzenesulfonic Acid results in decreased expression of IL10; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein
[cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein] 		CTD
RGD		 PMID:11717450 PMID:15604057 PMID:15973123 PMID:16867261 PMID:17375199 More... RGD:152995414 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12a interleukin 12A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA CTD PMID:15973123 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B decreases response to substance
increases expression
multiple interactions 		ISO
EXP 		IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid
Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein]
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] 		CTD PMID:11782017 PMID:16867261 PMID:17375199 PMID:23596210 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il15 interleukin 15 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL15 protein CTD PMID:23596210 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of IL17A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]
[Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein 		CTD PMID:17375199 PMID:23027085 PMID:27783946 PMID:31428839 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] 		CTD PMID:15973123 PMID:30365937 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein] 		CTD PMID:12781210 PMID:23596210 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		ISO
EXP 		Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] 		CTD PMID:15140218 PMID:15604057 PMID:15793857 PMID:15867298 PMID:15973123 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions
increases expression 		EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] CTD PMID:17449585 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL1RL1 mRNA CTD PMID:17982090 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression 		EXP Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA] CTD PMID:15867298 PMID:17375077 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression 		ISO seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL2 mRNA] CTD PMID:11717450 PMID:27783946 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL23A mRNA CTD PMID:17375199 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il4 interleukin 4 increases expression
decreases secretion
decreases expression
multiple interactions 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of IL4 mRNA
Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein] 		CTD PMID:15973123 PMID:16782535 PMID:16867261 PMID:25729217 PMID:27783946 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression 		ISO
EXP 		Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IL6 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of IL6; Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein 		CTD PMID:17375199 PMID:18079364 PMID:18200517 PMID:19956958 PMID:19998380 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Insl3 insulin-like 3 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of INSL3 mRNA CTD PMID:23537331 NCBI chr16:18,432,668...18,434,539 JBrowse link
G Irf1 interferon regulatory factor 1 decreases response to substance ISO IRF1 protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:21097874 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ISG15 mRNA CTD PMID:17982090 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656 		JBrowse link
G Itm2a integral membrane protein 2A multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA] CTD PMID:18200517 NCBI chr  X:76,559,183...76,565,144
Ensembl chr  X:76,559,181...76,565,437 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA CTD PMID:23537331 NCBI chr 4:180,759,325...181,165,361
Ensembl chr 4:180,760,442...181,164,763 		JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein] 		CTD PMID:33522063 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein CTD PMID:22427801 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCNAB1 mRNA CTD PMID:23537331 NCBI chr 2:151,446,975...151,913,636
Ensembl chr 2:151,446,947...151,913,636 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of KCNJ4 mRNA CTD PMID:23537331 NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:112,922,532...112,954,826 		JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCNQ4 mRNA CTD PMID:23537331 NCBI chr 5:139,560,366...139,612,212
Ensembl chr 5:139,560,366...139,612,102 		JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCTD9 mRNA CTD PMID:23537331 NCBI chr15:46,117,211...46,145,258
Ensembl chr15:46,117,874...46,145,266 		JBrowse link
G Kitlg KIT ligand increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KITLG mRNA CTD PMID:17385238 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793 		JBrowse link
G Kl Klotho multiple interactions
decreases expression 		ISO KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of KL protein 		CTD PMID:23747339 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015 		JBrowse link
G L1cam L1 cell adhesion molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of L1CAM mRNA CTD PMID:17982090 NCBI chr  X:156,748,597...156,775,116
Ensembl chr  X:156,748,597...156,775,077 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LAMA3 mRNA CTD PMID:17982090 NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449 		JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA] CTD PMID:18200517 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA] 		CTD PMID:18200517 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092 		JBrowse link
G Lgmn legumain multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA] CTD PMID:18200517 NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LILRB4 mRNA CTD PMID:17982090 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:78,847,685...78,853,326 		JBrowse link
G Lox lysyl oxidase multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA CTD PMID:17982090 NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LST1 mRNA CTD PMID:17982090 NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,639,341...3,642,669 		JBrowse link
G Lum lumican increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LUM mRNA CTD PMID:17982090 NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LY6A mRNA CTD PMID:17982090 NCBI chr 7:109,064,222...109,067,757 JBrowse link
G Ly86 lymphocyte antigen 86 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LY86 mRNA CTD PMID:17982090 NCBI chr17:27,621,313...27,705,336
Ensembl chr17:27,621,313...27,692,743 		JBrowse link
G Lyz2 lysozyme 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011 		JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA] CTD PMID:18200517 NCBI chr 7:10,686,920...10,690,322
Ensembl chr 7:10,686,250...10,690,322 		JBrowse link
G Maf MAF bZIP transcription factor increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MAF protein
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF protein] 		CTD PMID:24066068 NCBI chr19:60,259,200...60,622,145
Ensembl chr19:60,269,541...60,621,378 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MANF mRNA CTD PMID:17982090 NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:116,427,048...116,429,910 		JBrowse link
G Maoa monoamine oxidase A multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA] CTD PMID:18200517 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation 		EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] CTD PMID:30503585 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of MAP3K6 mRNA CTD PMID:23537331 NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of MAPK6 mRNA CTD PMID:23537331 NCBI chr 8:85,027,141...85,050,236
Ensembl chr 8:85,027,144...85,050,236 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
increases phosphorylation
multiple interactions 		EXP
ISO 		Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA
Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein
TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein] 		CTD PMID:23537331 PMID:39237074 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases expression 		ISO [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] CTD PMID:22427801 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Marcksl1 MARCKS-like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MARCKSL1 mRNA CTD PMID:17982090 NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNA CTD PMID:17982090 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275 		JBrowse link
G Mgp matrix Gla protein increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNA CTD PMID:17982090 NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859 		JBrowse link
G Mir155 microRNA 155 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA] 		CTD PMID:24066068 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mir29a microRNA 29a increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR29A mRNA CTD PMID:25277410 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir29b1 microRNA 29b-1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR29B-1 mRNA CTD PMID:25277410 NCBI chr 4:60,618,334...60,618,414 JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MKI67 mRNA CTD PMID:17982090 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression 		EXP ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein 		CTD PMID:18837084 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MMP12 mRNA CTD PMID:17982090 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478 		JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA] CTD PMID:18200517 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893 		JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MMP15 mRNA CTD PMID:17982090 NCBI chr19:9,669,506...9,691,000
Ensembl chr19:9,669,506...9,691,000 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA] CTD PMID:18200517 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein CTD PMID:22119283 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFI204 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of MNDA mRNA 		CTD PMID:17982090 NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of MOXD2 mRNA CTD PMID:17982090 NCBI chr 4:70,691,373...70,699,868
Ensembl chr 4:70,691,373...70,699,868 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression 		EXP
ISO 		4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Indomethacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Spironolactone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; tin protoporphyrin IX promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zileuton inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
2,4,6-trinitrobenzenesulfonic acid increases myeloperoxidase enzyme activity in rat colon
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; J 113397 inhibits the reaction [8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; morphiceptin analog affects the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; RN 1734 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
Trinitrobenzenesulfonic Acid results in increased expression of MPO; Trinitrobenzenesulfonic Acid results in increased expression of MPO protein 		CTD
RGD		 PMID:10845656 PMID:10877837 PMID:11137876 PMID:11504810 PMID:11668029 More... RGD:152995414 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MRC1 mRNA CTD PMID:17982090 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MRM3 mRNA CTD PMID:17982090 NCBI chr10:61,594,155...61,623,659
Ensembl chr10:61,593,999...61,600,865 		JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA] CTD PMID:18200517 NCBI chr 2:117,436,199...117,447,790
Ensembl chr 2:117,428,621...117,447,517 		JBrowse link
G Msn moesin multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA] CTD PMID:18200517 NCBI chr  X:65,005,546...65,073,512
Ensembl chr  X:65,005,458...65,075,129 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein] 		CTD PMID:33412153 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Muc17 mucin 17, cell surface associated increases expression
decreases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of MUC17 mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of MUC17 mRNA
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC17 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC17 mRNA] 		CTD PMID:17375077 PMID:17449585 NCBI chr12:25,139,076...25,175,249 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions
decreases expression
increases expression 		EXP
ISO 		Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNA 		CTD PMID:17449585 PMID:19998380 PMID:25307695 NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280 		JBrowse link
G Muc4 mucin 4, cell surface associated multiple interactions
increases expression 		EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA] CTD PMID:15867298 PMID:17449585 NCBI chr11:81,513,321...81,575,200 JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions
increases expression 		EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]
Trinitrobenzenesulfonic Acid results in increased expression of MYD88; Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein 		CTD PMID:16891783 PMID:19002562 PMID:35290143 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase increases secretion EXP Trinitrobenzenesulfonic Acid results in increased secretion of NAGLU protein CTD PMID:23307618 NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,501,836...86,509,315 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects expression
decreases expression 		EXP 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA] CTD PMID:31428839 PMID:31669340 PMID:33412153 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] 		CTD PMID:26165751 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression
increases degradation 		EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein] CTD PMID:15793857 PMID:30365937 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Ngf nerve growth factor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NGF mRNA CTD PMID:17385238 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression 		EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] CTD PMID:30365937 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nmt2 N-myristoyltransferase 2 decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA] 		CTD PMID:18200517 NCBI chr17:79,826,999...79,874,088
Ensembl chr17:79,826,999...79,870,259 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 increases expression ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of NOD2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOD2 protein CTD PMID:16891783 PMID:22147983 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases activity
increases expression
affects response to substance 		ISO
EXP 		Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]
Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein
Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein
NOS2 protein affects the susceptibility to Trinitrobenzenesulfonic Acid
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Sulfasalazine affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA] 		CTD PMID:10845656 PMID:11504810 PMID:11698051 PMID:11717450 PMID:15867298 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NPY1R mRNA CTD PMID:23537331 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of NQO1 mRNA CTD PMID:19524605 PMID:22609641 PMID:25724174 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 protein CTD PMID:21829567 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid; [Rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid 		CTD PMID:21599020 PMID:21829567 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA CTD PMID:23537331 NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:9,776,179...9,785,924 		JBrowse link
G Nts neurotensin multiple interactions ISO NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] CTD PMID:25307345 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961 		JBrowse link
G Ntsr1 neurotensin receptor 1 multiple interactions
increases response to substance 		ISO NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid 		CTD PMID:25307345 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:187,983,778...188,033,934 		JBrowse link
G Nucb2 nucleobindin 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNA CTD PMID:17982090 NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116 		JBrowse link
G Ocln occludin multiple interactions
decreases expression 		ISO
EXP 		Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]
Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein] 		CTD PMID:22147983 PMID:22849695 PMID:25307695 PMID:35290143 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ODC1 mRNA CTD PMID:12163651 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions
increases expression 		EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein 		CTD PMID:24637189 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:149,590,244...149,624,999 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of OPRL1 mRNA CTD PMID:23537331 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:189,212,175...189,217,426 		JBrowse link
G Or2h1 olfactory receptor family 2 subfamily H member 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of OR2H1 mRNA CTD PMID:17982090 NCBI chr20:1,451,227...1,452,165
Ensembl chr20:1,451,227...1,452,165 		JBrowse link
G Or2h2c olfactory receptor family 2 subfamily H member 2C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of OR2H2 mRNA CTD PMID:17982090 NCBI chr20:1,404,211...1,405,149
Ensembl chr20:1,404,211...1,405,149 		JBrowse link
G Osmr oncostatin M receptor multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561 		JBrowse link
G Otud4 OTU deubiquitinase 4 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of OTUD4 mRNA CTD PMID:17982090 NCBI chr19:45,141,043...45,184,136
Ensembl chr19:45,141,043...45,184,136 		JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA CTD PMID:23537331 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G P2ry1 purinergic receptor P2Y1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RY1 mRNA CTD PMID:23537331 NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027 		JBrowse link
G P2ry13 purinergic receptor P2Y13 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RY13 mRNA CTD PMID:23537331 NCBI chr 2:145,620,321...145,624,730
Ensembl chr 2:145,619,655...145,622,787 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PAK2 mRNA CTD PMID:23537331 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of PCK1 mRNA CTD PMID:17982090 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PCNA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PCNA protein CTD PMID:19234664 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PDIA3 mRNA CTD PMID:17982090 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327 		JBrowse link
G Pdpn podoplanin multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA] CTD PMID:18200517 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein] 		CTD PMID:22410118 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA] CTD PMID:18200517 NCBI chr10:103,713,306...103,748,924
Ensembl chr10:103,713,316...103,749,233 		JBrowse link
G Pir pirin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PIR mRNA CTD PMID:19524605 PMID:22609641 NCBI chr  X:33,740,428...33,851,049
Ensembl chr  X:33,740,429...33,851,049 		JBrowse link
G Pirb paired Ig-like receptor B multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA] CTD PMID:18200517 NCBI chr 1:74,414,556...74,433,015
Ensembl chr 1:74,331,291...74,422,116 		JBrowse link
G Pklr pyruvate kinase L/R increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PKLR mRNA CTD PMID:17982090 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PLA2G12A mRNA CTD PMID:17982090 NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964 		JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PLA2G7 mRNA CTD PMID:17982090 NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA] 		CTD PMID:18200517 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022 		JBrowse link
G Pnliprp1 pancreatic lipase-related protein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PNLIPRP1 mRNA CTD PMID:17982090 NCBI chr 1:267,854,027...267,869,654
Ensembl chr 1:267,854,027...267,869,654 		JBrowse link
G Pomc proopiomelanocortin decreases expression
increases expression 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in decreased expression of POMC mRNA
Trinitrobenzenesulfonic Acid results in increased expression of POMC protein 		CTD PMID:11959675 PMID:25307695 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression 		EXP
ISO 		Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein 		CTD PMID:16782535 PMID:19617644 PMID:21829567 PMID:24831514 PMID:26165751 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Prkci protein kinase C, iota increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PRKCI mRNA CTD PMID:23537331 NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:114,250,398...114,310,784 		JBrowse link
G Prss1 serine protease 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PRSS1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRY10 mRNA CTD PMID:17982090 NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452 		JBrowse link
G Prss3 serine protease 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PRSS3 mRNA CTD PMID:17982090 NCBI chr 4:71,169,749...71,173,223
Ensembl chr 4:71,169,749...71,173,223 		JBrowse link
G Psme3 proteasome activator subunit 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PSME3 mRNA CTD PMID:17982090 NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGER2 mRNA CTD PMID:23537331 PMID:25526689 NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of PTGER4 mRNA CTD PMID:25526689 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Ptges prostaglandin E synthase increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGES mRNA CTD PMID:25526689 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptgir prostaglandin I2 receptor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGIR mRNA CTD PMID:25526689 NCBI chr 1:86,707,690...86,710,073
Ensembl chr 1:86,707,503...86,711,874 		JBrowse link
G Ptgis prostaglandin I2 synthase increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGIS mRNA CTD PMID:25526689 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of PTGS1 mRNA CTD PMID:25526689 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression 		ISO
EXP 		Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of PTGS2 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA] 		CTD PMID:11137876 PMID:11698051 PMID:11717450 PMID:11820457 PMID:15973123 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PTPRC mRNA CTD PMID:17982090 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA] CTD PMID:18200517 NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903 		JBrowse link
G Ptx3 pentraxin 3 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA] 		CTD PMID:18200517 NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372 		JBrowse link
G Rab10 RAB10, member RAS oncogene family decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of RAB10 mRNA CTD PMID:23537331 NCBI chr 6:31,974,858...32,039,554
Ensembl chr 6:31,986,921...32,039,733 		JBrowse link
G Rab15 RAB15, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA CTD PMID:23537331 NCBI chr 6:101,232,740...101,257,388
Ensembl chr 6:101,232,743...101,257,083 		JBrowse link
G Rab39a RAB39A, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB39A mRNA CTD PMID:23537331 NCBI chr 8:62,984,434...63,002,053
Ensembl chr 8:62,984,434...63,002,053 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB5A mRNA CTD PMID:23537331 NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,721,122...6,749,447 		JBrowse link
G Ramp2 receptor activity modifying protein 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAMP2 mRNA CTD PMID:21808981 NCBI chr10:86,689,148...86,690,956
Ensembl chr10:86,688,703...86,691,231 		JBrowse link
G Ramp3 receptor activity modifying protein 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAMP3 mRNA CTD PMID:21808981 NCBI chr14:85,741,314...85,758,813
Ensembl chr14:85,755,211...85,758,818 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAP1B mRNA CTD PMID:23537331 NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:55,308,922...55,342,217 		JBrowse link
G Rasa2 RAS p21 protein activator 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RASA2 mRNA CTD PMID:23537331 NCBI chr 8:105,996,797...106,116,285
Ensembl chr 8:106,000,002...106,116,206 		JBrowse link
G Rasa3 RAS p21 protein activator 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RASA3 mRNA CTD PMID:23537331 NCBI chr16:82,557,556...82,671,527
Ensembl chr16:82,557,428...82,672,984 		JBrowse link
G Rasd2 RASD family, member 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of RASD2 mRNA CTD PMID:23537331 NCBI chr19:13,600,028...13,610,753
Ensembl chr19:13,599,986...13,610,753 		JBrowse link
G Rbp1 retinol binding protein 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:107,887,417...107,983,847 		JBrowse link
G Reg3b regenerating family member 3 beta increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of REG3B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA] 		CTD PMID:17982090 PMID:18200517 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases abundance
increases phosphorylation
increases expression
affects localization 		EXP
ISO 		Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Nf-Kb protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of RELA protein
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein] 		CTD
RGD		 PMID:16474422 PMID:19597321 PMID:19956958 PMID:21070844 PMID:22410118 More... RGD:152995414 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Retnlb resistin like beta increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA] 		CTD PMID:18200517 NCBI chr11:65,446,433...65,448,319
Ensembl chr11:65,446,434...65,448,319 		JBrowse link
G Rhoq ras homolog family member Q increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RHOQ mRNA CTD PMID:23537331 NCBI chr 6:13,368,499...13,403,929
Ensembl chr 1:115,757,909...115,759,467 		JBrowse link
G Rmnd1 required for meiotic nuclear division 1 homolog decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of RMND1 mRNA CTD PMID:17982090 NCBI chr 1:43,265,207...43,299,748
Ensembl chr 1:43,265,207...43,299,682 		JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNA CTD PMID:17982090 NCBI chr15:26,835,436...26,837,145
Ensembl chr15:26,835,463...26,837,248 		JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RNGTT mRNA CTD PMID:17982090 NCBI chr 5:52,503,335...52,709,604
Ensembl chr 5:52,503,313...52,709,597 		JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of RPRM mRNA CTD PMID:17982090 NCBI chr 3:58,948,618...58,950,035
Ensembl chr 3:58,799,866...58,950,542 		JBrowse link
G Rreb1 ras responsive element binding protein 1 multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA] CTD PMID:18200517 NCBI chr17:27,082,217...27,208,061
Ensembl chr17:27,082,227...27,208,061 		JBrowse link
G RT1-Ba RT1 class II, locus Ba increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of H2-AA mRNA CTD PMID:17982090 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G RT1-Da RT1 class II, locus Da increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of H2-EA mRNA CTD PMID:17982090 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G Ryr1 ryanodine receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA CTD PMID:23537331 NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of SAT1 mRNA CTD PMID:12163651 NCBI chr  X:44,008,089...44,011,376
Ensembl chr  X:44,006,781...44,011,374 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SCD1 mRNA CTD PMID:17982090 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SCN10A CTD PMID:15205116 NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:128,228,424...128,340,298 		JBrowse link
G Selenow selenoprotein W increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SELENOW mRNA CTD PMID:17982090 NCBI chr 1:85,727,631...85,732,703
Ensembl chr 1:85,727,632...85,732,703 		JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SERPINB5 mRNA CTD PMID:17982090 NCBI chr13:23,500,203...23,520,401
Ensembl chr13:23,500,198...23,520,400 		JBrowse link
G Serpine2 serpin family E member 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA] CTD PMID:18200517 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202 		JBrowse link
G Shbg sex hormone binding globulin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNA CTD PMID:17982090 NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760 		JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SIRT1 protein CTD PMID:24782617 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 protein CTD PMID:12044520 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC1A1 mRNA CTD PMID:17982090 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249 		JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC26A2 mRNA CTD PMID:17982090 NCBI chr18:56,918,662...56,937,032
Ensembl chr18:56,923,337...56,937,012 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA] 		CTD PMID:18200517 NCBI chr13:99,529,664...99,584,442
Ensembl chr13:99,529,790...99,544,213 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SLC4A4 mRNA CTD PMID:17982090 NCBI chr14:19,125,394...19,577,379
Ensembl chr14:19,129,264...19,577,435 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A1 protein CTD PMID:12044520 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 protein CTD PMID:12044520 NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1B2 mRNA CTD PMID:12044520 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083 		JBrowse link
G Slfn4 schlafen family member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SLFN4 mRNA CTD PMID:17982090 NCBI chr10:68,492,135...68,515,674 JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA] CTD PMID:18200517 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SMC2 mRNA CTD PMID:17982090 NCBI chr 5:71,592,428...71,648,636
Ensembl chr 5:71,602,308...71,648,632 		JBrowse link
G Smpx small muscle protein, X-linked multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA] CTD PMID:18200517 NCBI chr  X:41,049,354...41,107,323
Ensembl chr  X:41,049,356...41,107,137 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression
increases abundance
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein
2,4,6-trinitrobenzenesulfonic acid increases abundance of Socs3 protein in rat colon
cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein] 		CTD
RGD		 PMID:33522063 PMID:29572553 RGD:152995414 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA] CTD PMID:17994277 PMID:18200517 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA
Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] 		CTD PMID:14555839 PMID:17982090 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression 		EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srgn serglycin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNA CTD PMID:17982090 NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327 		JBrowse link
G Srm spermidine synthase multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA] CTD PMID:18200517 NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNA CTD PMID:17982090 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
multiple interactions 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein] 		CTD PMID:25740948 PMID:30365937 PMID:33522063 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stim1 stromal interaction molecule 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of STIM1 mRNA CTD PMID:17982090 NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:166,067,962...166,233,108 		JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of STK17B mRNA CTD PMID:23537331 NCBI chr 9:62,801,912...62,832,511
Ensembl chr 9:62,803,005...62,832,511 		JBrowse link
G Sulf2 sulfatase 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA] CTD PMID:18200517 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651 		JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA CTD PMID:17982090 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions
affects response to substance 		ISO TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]
TACR1 protein affects the susceptibility to Trinitrobenzenesulfonic Acid 		CTD PMID:20889569 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492 		JBrowse link
G Tes testin LIM domain protein decreases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in decreased expression of TES protein
Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MAPK8 protein] 		CTD PMID:39237074 NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:46,331,257...46,369,780 		JBrowse link
G Tff3 trefoil factor 3 multiple interactions
increases expression 		EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA] CTD PMID:15867298 PMID:17449585 NCBI chr20:9,194,623...9,199,333
Ensembl chr20:9,194,626...9,199,333 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
decreases expression 		ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of TGFB1 protein; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TGFB1 mRNA 		CTD PMID:20889569 PMID:21599020 PMID:25307695 PMID:25740948 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TGFB2 mRNA CTD PMID:25307695 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TGFBR1 mRNA CTD PMID:23537331 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA] CTD PMID:18200517 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240 		JBrowse link
G Tgm3 transglutaminase 3 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TGM3 mRNA CTD PMID:17982090 NCBI chr 3:137,681,809...137,717,219
Ensembl chr 3:137,681,809...137,717,219 		JBrowse link
G Thbd thrombomodulin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of THBD mRNA CTD PMID:17982090 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA] CTD PMID:18200517 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Thy1 Thy-1 cell surface antigen increases expression
multiple interactions 		ISO Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA] 		CTD PMID:18200517 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression 		ISO
EXP 		Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein] 		CTD PMID:17982090 PMID:18200517 PMID:18837084 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression 		ISO
EXP 		ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]
oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein 		CTD PMID:22147983 PMID:22849695 PMID:35290143 PMID:39237074 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tjp2 tight junction protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TJP2 mRNA CTD PMID:25307695 NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:231,136,243...231,264,750 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TLR2 CTD PMID:16891783 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
decreases expression 		ISO
EXP 		lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TLR4; Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein] 		CTD PMID:16891783 PMID:19002562 PMID:19597321 PMID:19956958 PMID:19998380 More... NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
increases expression 		EXP oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR9 protein] CTD PMID:35290143 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Tmem245 transmembrane protein 245 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of TMEM245 mRNA CTD PMID:12163651 NCBI chr 5:76,366,157...76,443,108
Ensembl chr 5:76,366,157...76,442,888 		JBrowse link
G Tmt1a thiol methyltransferase 1A multiple interactions
decreases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TMT1A mRNA] CTD PMID:18200517 NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:133,330,447...133,338,959 		JBrowse link
G Tnc tenascin C multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA] CTD PMID:18200517 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
increases expression
increases secretion 		ISO
EXP 		[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Anisomycin inhibits the reaction [TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; TES protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
2,4,6-trinitrobenzenesulfonic acid increases abundance of Tnfa protein in rat colon
Trinitrobenzenesulfonic Acid results in increased expression of TNF; Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TNF protein
Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cinnamaldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; iberogast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] 		CTD
RGD		 PMID:11717450 PMID:12717850 PMID:16474422 PMID:16782535 PMID:16867261 More... RGD:152995414 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases response to substance ISO TNFRSF25 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:20980995 NCBI chr 5:167,904,377...167,909,052
Ensembl chr 5:167,904,786...167,909,052 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TNFSF11 protein CTD PMID:23747339 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnfsf15 TNF superfamily member 15 increases response to substance ISO TNFSF15 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:20980995 NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:82,150,376...82,171,882 		JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TNFSF4 mRNA CTD PMID:23537331 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		ISO
EXP 		D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein]
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein
Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein 		CTD PMID:22427801 PMID:30503585 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Trim15 tripartite motif containing 15 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA] CTD PMID:18200517 NCBI chr20:1,703,723...1,715,465
Ensembl chr20:1,706,122...1,715,465 		JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRIM16 mRNA CTD PMID:19524605 PMID:22609641 NCBI chr10:47,985,235...48,008,242
Ensembl chr10:47,958,677...48,051,136 		JBrowse link
G Trip4 thyroid hormone receptor interactor 4 increases expression
multiple interactions 		EXP Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein] 		CTD PMID:30365937 NCBI chr 8:75,248,352...75,334,802
Ensembl chr 8:75,248,361...75,335,055 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA CTD PMID:23537331 NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:121,409,436...121,475,823 		JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRPM8 mRNA CTD PMID:23596210 NCBI chr 9:96,315,567...96,437,959
Ensembl chr 9:96,351,681...96,436,617 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases expression
decreases expression 		EXP topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 protein 		CTD PMID:17698068 PMID:17991707 PMID:21849664 PMID:25445197 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA CTD PMID:22882778 NCBI chr12:47,599,161...47,638,143
Ensembl chr12:47,599,035...47,638,143 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]; Trinitrobenzenesulfonic Acid results in decreased expression of and results in increased metabolism of TRPV5 protein CTD PMID:23747339 NCBI chr 4:71,503,085...71,531,134
Ensembl chr 4:71,503,093...71,529,384 		JBrowse link
G Txndc16 thioredoxin domain containing 16 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TXNDC16 mRNA CTD PMID:17982090 NCBI chr15:20,831,541...20,905,661
Ensembl chr15:20,831,391...20,905,452 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
G Ubc ubiquitin C increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of UBC mRNA CTD PMID:12163651 NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275 		JBrowse link
G Ubd ubiquitin D increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of UBD mRNA CTD PMID:17982090 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,390,600...1,413,965 		JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of UBE2W mRNA CTD PMID:17982090 NCBI chr 5:7,474,039...7,531,526
Ensembl chr 5:7,474,003...7,598,245 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:12163651 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Usp8 ubiquitin specific peptidase 8 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of USP8 mRNA CTD PMID:23537331 NCBI chr 3:134,413,832...134,463,040
Ensembl chr 3:134,415,391...134,463,032 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions 		ISO
EXP 		Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein 		CTD PMID:17982090 PMID:22029500 PMID:30503585 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vcan versican multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA] CTD PMID:18200517 NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression 		EXP
ISO 		Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA] 		CTD PMID:21893697 PMID:25307345 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin multiple interactions
increases expression 		ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] CTD PMID:20889569 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vnn1 vanin 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of VNN1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VNN1 protein CTD PMID:23307618 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629 		JBrowse link
G Vwf von Willebrand factor multiple interactions
increases expression 		ISO NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] CTD PMID:25307345 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
G Wdr48 WD repeat domain 48 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of WDR48 mRNA CTD PMID:17982090 NCBI chr 8:128,499,721...128,532,930
Ensembl chr 8:128,499,716...128,532,930 		JBrowse link
G Wfdc18 WAP four-disulfide core domain 18 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of WFDC18 mRNA CTD PMID:17982090 NCBI chr10:69,086,319...69,088,473
Ensembl chr10:69,086,319...69,087,172 		JBrowse link
G Zc3h11a zinc finger CCCH-type containing 11A decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNA CTD PMID:17982090 NCBI chr13:47,625,444...47,665,971 JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ZFP36L2 mRNA CTD PMID:17982090 NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:16,242,610...16,246,653 		JBrowse link
2,4-dinitrobenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases expression EXP 2,4-dinitrobenzenesulfonic acid results in increased expression of ADA mRNA CTD PMID:20860664 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ADARB1 mRNA CTD PMID:30116771 NCBI chr20:11,222,171...11,350,416
Ensembl chr20:11,222,164...11,350,415 		JBrowse link
G Adora3 adenosine A3 receptor increases expression EXP 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 mRNA; 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 protein CTD PMID:20860664 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ATF3 mRNA CTD PMID:30116771 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of BNIP3 mRNA CTD PMID:30116771 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Caly calcyon neuron-specific vesicular protein decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CALY mRNA CTD PMID:30116771 NCBI chr 1:204,292,317...204,303,506
Ensembl chr 1:204,292,318...204,303,196 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CCL7 mRNA CTD PMID:30116771 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CCR2 mRNA CTD PMID:30116771 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Cdh4 cadherin 4 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CDH4 mRNA CTD PMID:30116771 NCBI chr 3:186,902,763...187,381,020
Ensembl chr 3:186,902,751...187,381,020 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CIAPIN1 mRNA CTD PMID:30116771 NCBI chr19:10,185,955...10,199,120
Ensembl chr19:10,182,088...10,201,495 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases response to substance ISO CNR1 results in decreased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO 2,4-dinitrobenzenesulfonic acid affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNA CTD PMID:30116771 NCBI chr16:18,958,695...18,970,026
Ensembl chr16:18,957,956...18,969,970 		JBrowse link
G Ctnna3 catenin alpha 3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CTNNA3 mRNA CTD PMID:30116771 NCBI chr20:23,613,016...25,198,699
Ensembl chr20:23,613,016...25,198,805 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CXCL1 mRNA CTD PMID:30116771 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions
decreases expression 		ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of DLC1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of DLC1 mRNA 		CTD PMID:30116771 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819 		JBrowse link
G Faah fatty acid amide hydrolase increases response to substance ISO FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396 		JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of FAT4 mRNA CTD PMID:30116771 NCBI chr 2:123,855,289...123,984,716
Ensembl chr 2:123,855,289...123,984,716 		JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of FHL2 mRNA CTD PMID:30116771 NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326 		JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of FHL3 mRNA CTD PMID:30116771 NCBI chr 5:142,238,634...142,246,011
Ensembl chr 5:142,235,109...142,246,034 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of GCNT2 mRNA CTD PMID:30116771 NCBI chr17:24,002,592...24,107,339
Ensembl chr17:24,002,597...24,106,989 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions 		ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA
GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA] 		CTD PMID:30116771 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA CTD PMID:30116771 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of IL10RA mRNA CTD PMID:30116771 NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028 		JBrowse link
G Il6 interleukin 6 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of IL6 mRNA CTD PMID:30116771 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase multiple interactions
decreases expression 		ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of ITPK1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of ITPK1 mRNA 		CTD PMID:30116771 NCBI chr 6:127,475,589...127,609,320
Ensembl chr 6:127,476,808...127,609,062 		JBrowse link
G Jaml junction adhesion molecule like increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of JAML mRNA CTD PMID:30116771 NCBI chr 8:54,281,596...54,313,655
Ensembl chr 8:54,281,644...54,313,500 		JBrowse link
G Kalrn kalirin, RhoGEF kinase increases expression
multiple interactions 		ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNA 		CTD PMID:30116771 NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329 		JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 multiple interactions
decreases expression 		ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KCNB2 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of KCNB2 mRNA 		CTD PMID:30116771 NCBI chr 5:8,340,085...8,811,184
Ensembl chr 5:8,351,961...8,783,179 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of LIF mRNA CTD PMID:30116771 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of MFSD6 mRNA CTD PMID:30116771 NCBI chr 9:56,265,152...56,350,449
Ensembl chr 9:56,265,237...56,350,446 		JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of MSH2 mRNA CTD PMID:30116771 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Nfix nuclear factor I X decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of NFIX mRNA CTD PMID:30116771 NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression ISO 2,4-dinitrobenzenesulfonic acid affects the expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions
decreases expression 		ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of NT5E mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of NT5E mRNA 		CTD PMID:30116771 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ODC1 mRNA CTD PMID:30116771 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Oprk1 opioid receptor, kappa 1 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of OPRK1 mRNA CTD PMID:30116771 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:18,657,871...18,675,671 		JBrowse link
G Pde4d phosphodiesterase 4D multiple interactions
decreases expression 		ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PDE4D mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of PDE4D mRNA 		CTD PMID:30116771 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:42,110,838...43,262,569 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PIK3C2A mRNA CTD PMID:30116771 NCBI chr 1:180,012,248...180,117,786
Ensembl chr 1:180,012,248...180,117,773 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA CTD PMID:30116771 NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression
multiple interactions 		ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PTGER4 mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PTGER4 mRNA 		CTD PMID:30116771 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Rps15a ribosomal protein S15a increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of RPS15A mRNA CTD PMID:30116771 NCBI chr 1:181,854,396...181,861,330
Ensembl chr 1:181,854,396...181,861,201 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-T23 mRNA CTD PMID:30116771 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-Ba RT1 class II, locus Ba decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-AA mRNA CTD PMID:30116771 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G Sgcd sarcoglycan, delta decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of SGCD mRNA CTD PMID:30116771 NCBI chr10:31,847,713...32,829,554
Ensembl chr10:31,781,748...32,419,064 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of SLC9A1 mRNA CTD PMID:30116771 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:150,860,228...150,913,517 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression 		ISO GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA] CTD PMID:30116771 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tacr2 tachykinin receptor 2 multiple interactions ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in decreased expression of TACR2 mRNA CTD PMID:30116771 NCBI chr20:30,751,645...30,766,181
Ensembl chr20:30,751,557...30,766,180 		JBrowse link
G Taf1b TATA-box binding protein associated factor, RNA polymerase I subunit B multiple interactions
decreases expression 		ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of TAF1B mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of TAF1B mRNA 		CTD PMID:30116771 NCBI chr 6:46,845,571...46,923,209
Ensembl chr 6:46,846,029...46,923,209 		JBrowse link
G Tapbpl TAP binding protein-like decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of TAPBPL mRNA CTD PMID:30116771 NCBI chr 4:159,707,686...159,715,137
Ensembl chr 4:159,708,511...159,715,137 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of THBS1 mRNA CTD PMID:30116771 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of TNF mRNA CTD PMID:20385217 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Trim62 tripartite motif-containing 62 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of TRIM62 mRNA CTD PMID:30116771 NCBI chr 5:146,516,349...146,545,015
Ensembl chr 5:146,515,090...146,545,015 		JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A increases expression
multiple interactions 		ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of VTI1A mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of VTI1A mRNA 		CTD PMID:30116771 NCBI chr 1:264,361,538...264,667,171
Ensembl chr 1:264,361,522...264,668,727 		JBrowse link
3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP metanil yellow results in decreased activity of ACHE protein CTD PMID:39703340 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Alb albumin multiple interactions EXP [Tartrazine co-treated with metanil yellow co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of ALB protein CTD PMID:26862277 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Cat catalase decreases activity
multiple interactions 		EXP metanil yellow results in decreased activity of CAT protein
[Tartrazine co-treated with metanil yellow co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in decreased activity of CAT protein; alpha-Tocopherol inhibits the reaction [metanil yellow results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [metanil yellow results in decreased activity of CAT protein]; Eugenol inhibits the reaction [metanil yellow results in decreased activity of CAT protein] 		CTD PMID:26494366 PMID:26862277 PMID:30738991 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions EXP [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein CTD PMID:12616621 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions 		EXP metanil yellow results in increased expression of CCND1 protein
[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein] 		CTD PMID:10906429 PMID:12616621 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne1 cyclin E1 multiple interactions
increases expression 		EXP metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein]
metanil yellow results in increased expression of CCNE1 protein 		CTD PMID:10906429 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions EXP [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 protein CTD PMID:12616621 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions EXP [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein CTD PMID:12616621 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression EXP metanil yellow results in decreased expression of FSHB CTD PMID:26494366 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases activity 		EXP alpha-Tocopherol inhibits the reaction [metanil yellow results in increased activity of GOT1 protein]; Ascorbic Acid inhibits the reaction [metanil yellow results in increased activity of GOT1 protein]; Eugenol inhibits the reaction [metanil yellow results in increased activity of GOT1 protein] CTD PMID:30738991 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions 		EXP metanil yellow results in increased activity of GPT protein
alpha-Tocopherol inhibits the reaction [metanil yellow results in increased activity of GPT protein]; Ascorbic Acid inhibits the reaction [metanil yellow results in increased activity of GPT protein]; Eugenol inhibits the reaction [metanil yellow results in increased activity of GPT protein] 		CTD PMID:30738991 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP metanil yellow results in decreased activity of GSR protein CTD PMID:26494366 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP metanil yellow results in decreased expression of LHB CTD PMID:26494366 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Maob monoamine oxidase B decreases activity EXP metanil yellow results in decreased activity of MAOB protein CTD PMID:39703340 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression 		EXP [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of PCNA protein; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of PCNA protein]
metanil yellow results in increased expression of PCNA protein 		CTD PMID:10906429 PMID:11831363 PMID:12616621 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase increases response to substance
multiple interactions 		ISO AICDA results in increased susceptibility to 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein 		CTD PMID:23589568 NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:157,444,697...157,456,356 		JBrowse link
G Alb albumin decreases uptake ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased uptake of ALB protein CTD PMID:16313995 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Ano6 anoctamin 6 decreases activity ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of ANO6 protein CTD PMID:24478309 NCBI chr 7:128,812,842...128,992,805
Ensembl chr 7:128,813,068...128,992,799 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ATF4 protein] CTD PMID:27638049 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; [Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein CTD PMID:18590702 PMID:28343033 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] CTD PMID:14766669 PMID:28343033 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
decreases activity 		ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CFTR protein 		CTD PMID:15131065 PMID:16038730 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases activity ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLCN3 protein CTD PMID:17699636 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984 		JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases activity EXP 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKA protein CTD PMID:15167890 NCBI chr 5:158,974,190...158,989,275
Ensembl chr 5:158,974,193...158,989,128 		JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases activity EXP 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid analog results in decreased activity of CLCNKB protein CTD PMID:15167890 NCBI chr 5:158,993,073...159,005,618
Ensembl chr 5:158,993,074...159,004,900 		JBrowse link
G Clic1 chloride intracellular channel 1 multiple interactions ISO [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine CTD PMID:18590702 NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of DDIT3 protein] 		CTD PMID:27638049 PMID:29421517 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of EIF2AK3 protein modified form] CTD PMID:27638049 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased phosphorylation of EIF2S1 protein] CTD PMID:27638049 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of HSPA5 protein] CTD PMID:29421517 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Ifng interferon gamma multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:11907163 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:11907163 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il1b interleukin 1 beta affects secretion
multiple interactions 		ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid affects the secretion of IL1B protein
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of IL1B mRNA] 		CTD PMID:15578659 PMID:27461142 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased expression of ITPR1 protein modified form] CTD PMID:27638049 NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:19815690 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein] CTD PMID:19815690 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Panx1 Pannexin 1 decreases activity ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of PANX1 protein CTD PMID:19023039 NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:20,132,165...20,171,200 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form] CTD PMID:28343033 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in decreased expression of PDCD6IP protein] CTD PMID:29421517 NCBI chr 8:122,469,223...122,524,993
Ensembl chr 8:122,469,223...122,524,993 		JBrowse link
G Rad51 RAD51 recombinase decreases activity
multiple interactions 		ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of RAD51 protein] which results in increased activity of AICDA protein 		CTD PMID:23589568 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in increased degradation of RARA protein] CTD PMID:17018029 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Sct secretin decreases activity ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SCT protein CTD PMID:10880878 NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:205,812,435...205,813,246 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases activity ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:31,301,243...31,382,957 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions ISO [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC19A1 protein] which results in decreased uptake of Folic Acid CTD PMID:17034785 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc46a1 solute carrier family 46 member 1 multiple interactions
decreases activity 		ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC46A1 protein results in increased transport of Folic Acid]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC46A1 protein 		CTD PMID:17475902 NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) multiple interactions
affects binding 		ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid binds to SLC4A1 protein 		CTD PMID:2511191 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [SLC4A2 protein results in increased uptake of Benzoic Acid] CTD PMID:9563070 NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:11,628,862...11,645,402 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 decreases activity EXP 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC4A4 protein CTD PMID:17325238 NCBI chr14:19,125,394...19,577,379
Ensembl chr14:19,129,264...19,577,435 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide] CTD PMID:12541134 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [morusin results in increased expression of SQSTM1 protein] CTD PMID:29421517 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [arsenic trioxide results in decreased expression of TGFB1 mRNA] CTD PMID:27461142 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] CTD PMID:10951577 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions EXP
ISO 		4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Staurosporine promotes the reaction [VDAC1 protein binds to VDAC1 protein]]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC1 protein binds to VDAC1 protein]] 		CTD PMID:20937774 PMID:28343033 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions ISO 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone promotes the reaction [VDAC2 protein binds to VDAC2 protein]] CTD PMID:29229420 NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,512,216...2,532,229 		JBrowse link
4,4'-dinitrostilbene-2,2'-disulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) multiple interactions ISO 4,4'-dinitro-2,2'-stilbenedisulfonic acid inhibits the reaction [SLC4A1 protein results in increased transport of Chlorides] CTD PMID:2511191 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258 		JBrowse link
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin multiple interactions EXP pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Fn1 fibronectin 1 decreases expression ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid results in decreased expression of FN1 mRNA CTD PMID:18210741 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein] CTD PMID:24793913 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:101,572,340...101,595,520 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions EXP pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] CTD PMID:11102496 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:138,235,754...138,236,594 		JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein] 		CTD PMID:21638035 PMID:31263019 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] CTD PMID:22253048 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747 		JBrowse link
7-amino-4-hydroxy-2-naphthalenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 affects activity ISO 7-amino-4-hydroxy-2-naphthalenesulfonic acid affects the activity of TP53 protein; 7-amino-4-hydroxy-2-naphthalenesulfonic acid metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
8-anilinonaphthalene-1-sulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambp alpha-1-microglobulin/bikunin precursor affects binding ISO 1-anilino-8-naphthalenesulfonate binds to AMBP protein CTD PMID:16461020 NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850 		JBrowse link
G Apod apolipoprotein D affects binding ISO 1-anilino-8-naphthalenesulfonate binds to APOD protein CTD PMID:16461020 NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263 		JBrowse link
G C8g complement C8 gamma chain affects binding ISO 1-anilino-8-naphthalenesulfonate binds to C8G protein CTD PMID:16461020 NCBI chr 3:28,718,648...28,720,232 JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to GSTA1 protein CTD PMID:14690442 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Lcn1 lipocalin 1 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to LCN1 protein CTD PMID:16461020 NCBI chr 3:29,930,943...29,935,418 JBrowse link
G Lcn2 lipocalin 2 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to LCN2 protein CTD PMID:16461020 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Obp2a odorant binding protein 2A affects binding ISO 1-anilino-8-naphthalenesulfonate binds to OBP2A protein CTD PMID:16461020 NCBI chr 3:28,904,024...28,907,391
Ensembl chr 3:28,902,876...28,907,389 		JBrowse link
G Orm1 orosomucoid 1 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to ORM1 protein CTD PMID:16461020 NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:81,788,395...81,791,667 		JBrowse link
G Paep progestagen associated endometrial protein affects binding ISO 1-anilino-8-naphthalenesulfonate binds to PAEP protein CTD PMID:16461020 NCBI chr 3:28,929,252...28,932,592 JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO 1-anilino-8-naphthalenesulfonate binds to PTGDS protein CTD PMID:16461020 NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978 		JBrowse link
G Ttr transthyretin affects binding
multiple interactions 		ISO 1-anilino-8-naphthalenesulfonate binds to TTR protein
3,3'-dichlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 3,4-dichlorinated biphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 4-chlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; Thyroxine inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein] 		CTD PMID:23584369 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969 		JBrowse link
bathocuproine disulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] CTD PMID:15477007 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA CTD PMID:15477007 NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] CTD PMID:15477007 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions ISO ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 mRNA]; ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] CTD PMID:20194531 NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585 		JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] CTD PMID:11092760 PMID:21242307 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:75,159,782...75,267,093 		JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions ISO [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein] CTD PMID:21242307 NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO bathocuproine sulfonate results in decreased expression of BCL2 protein CTD PMID:24614111 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]] CTD PMID:15477007 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein] CTD PMID:10941151 PMID:11239917 PMID:18056745 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]] CTD PMID:15477007 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]] CTD PMID:11006087 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] CTD PMID:15477007 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]] CTD PMID:15477007 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cd200 Cd200 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] CTD PMID:15477007 NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] CTD PMID:15477007 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cdh17 cadherin 17 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA CTD PMID:15477007 NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226 		JBrowse link
G Clu clusterin multiple interactions ISO [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein]; [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7B protein] CTD PMID:21242307 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cntnap1 contactin associated protein 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA CTD PMID:15477007 NCBI chr10:86,610,140...86,625,896
Ensembl chr10:86,611,890...86,631,730 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] CTD PMID:15477007 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cp ceruloplasmin multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein] CTD PMID:17032174 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Cpsf1 cleavage and polyadenylation specific factor 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA CTD PMID:15477007 NCBI chr 7:110,200,078...110,210,644
Ensembl chr 7:110,199,066...110,210,644 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA CTD PMID:15477007 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] CTD PMID:15477007 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Cul5 cullin 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] CTD PMID:15477007 NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which affects the localization of CYCS protein] CTD PMID:18056745 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA CTD PMID:15477007 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416 		JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]] CTD PMID:15477007 NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700 		JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] CTD PMID:15477007 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748 		JBrowse link
G Egr3 early growth response 3 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA CTD PMID:15477007 NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of FASN mRNA] CTD PMID:24170205 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:22842628 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]] CTD PMID:15477007 PMID:17032174 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fyb1 FYN binding protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] CTD PMID:15477007 NCBI chr 2:57,360,084...57,508,609
Ensembl chr 2:57,360,096...57,508,608 		JBrowse link
G Gfra2 GDNF family receptor alpha 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] CTD PMID:15477007 NCBI chr15:52,351,499...52,443,369
Ensembl chr15:52,351,514...52,477,782 		JBrowse link
G Gnas GNAS complex locus multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA CTD PMID:15477007 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA CTD PMID:15477007 NCBI chr 2:33,358,863...33,386,726
Ensembl chr 2:33,358,869...33,386,688 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] CTD PMID:15477007 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] CTD PMID:15477007 NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Penicillamine co-treated with bathocuproine sulfonate] results in increased expression of HMOX1 protein CTD PMID:21242307 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA CTD PMID:15477007 NCBI chr 1:90,356,182...90,391,923
Ensembl chr 1:90,356,182...90,390,370 		JBrowse link
G Hpx hemopexin multiple interactions ISO bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] affects the localization of MTF1 protein]; bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] results in increased expression of MTF1 mRNA]; bathocuproine sulfonate inhibits the reaction [[Heme co-treated with HPX protein] affects the localization of MTF1 protein] CTD PMID:11213479 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]] CTD PMID:15477007 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hyal3 hyaluronidase 3 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA CTD PMID:15477007 NCBI chr 8:117,133,028...117,138,663
Ensembl chr 8:117,132,649...117,139,289 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]] CTD PMID:15477007 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha multiple interactions ISO bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] CTD PMID:23134680 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] CTD PMID:15477007 NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:111,913,828...111,928,537 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]] CTD PMID:15477007 PMID:17032174 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] CTD PMID:15477007 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO bathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of LDLR mRNA] CTD PMID:24170205 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] CTD PMID:15477007 NCBI chr 1:91,727,769...91,759,822
Ensembl chr 1:91,727,769...91,760,006 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP 		bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]
bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein] 		CTD PMID:10658192 PMID:15477007 PMID:22842628 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP 		bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]
bathocuproine sulfonate inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]
bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein] 		CTD PMID:10941151 PMID:15477007 PMID:22842628 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein] CTD PMID:10941151 PMID:11239917 PMID:18056745 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1E mRNA CTD PMID:15477007 NCBI chr17:79,695,812...79,696,200
Ensembl chr17:79,695,809...79,696,200 		JBrowse link
G Mta1 metastasis associated 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MTA1 mRNA CTD PMID:15477007 NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] affects the localization of MTF1 protein]; bathocuproine sulfonate inhibits the reaction [[cobaltiprotoporphyrin co-treated with HPX protein] results in increased expression of MTF1 mRNA]; bathocuproine sulfonate inhibits the reaction [[Heme co-treated with HPX protein] affects the localization of MTF1 protein] CTD PMID:11213479 NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA] CTD PMID:15477007 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA] CTD PMID:15477007 NCBI chr 8:117,132,957...117,136,207
Ensembl chr 8:117,133,494...117,136,207 		JBrowse link
G Nell1 neural EGFL like 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA] CTD PMID:15477007 NCBI chr 1:108,845,462...109,709,858
Ensembl chr 1:108,845,462...109,709,858 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of NFE2L2 mRNA CTD PMID:15477007 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]] CTD PMID:11006087 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]] CTD PMID:11006087 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nmi N-myc (and STAT) interactor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA] CTD PMID:15477007 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:56,811,314...56,848,717 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA] CTD PMID:15477007 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ODC1 mRNA CTD PMID:15477007 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Pax8 paired box 8 multiple interactions EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA] CTD PMID:11108245 NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:27,584,002...27,640,631 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO bathocuproine sulfonate results in decreased expression of PCNA protein CTD PMID:24614111 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of PPP1R10 mRNA CTD PMID:15477007 NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418 		JBrowse link
G Prnp prion protein multiple interactions EXP bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein] CTD PMID:16148034 NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA] CTD PMID:15477007 NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938 		JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 increases oxidation ISO bathocuproine sulfonate results in increased oxidation of SCO1 protein CTD PMID:23345593 NCBI chr10:52,243,664...52,256,250
Ensembl chr10:52,243,648...52,260,861 		JBrowse link
G Sla src-like adaptor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] CTD PMID:15477007 NCBI chr 7:100,423,467...100,473,840
Ensembl chr 7:100,424,169...100,473,684 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO [bathocuproine sulfonate results in decreased abundance of Copper] which results in increased expression of SLC31A1 mRNA; bathocuproine sulfonate promotes the reaction [SP1 protein results in increased expression of SLC31A1 mRNA] CTD PMID:18483225 NCBI chr 5:80,830,574...80,859,810
Ensembl chr 5:80,830,389...80,859,809 		JBrowse link
G Slc31a2 solute carrier family 31 member 2 multiple interactions
affects localization 		ISO [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] which results in increased uptake of and results in increased susceptibility to Cisplatin; [bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein
bathocuproine sulfonate affects the localization of SLC31A2 protein
ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 mRNA]; ATOX1 protein affects the reaction [[bathocuproine sulfonate results in decreased abundance of Copper] which results in decreased expression of SLC31A2 protein] 		CTD PMID:20194531 NCBI chr 5:80,753,589...80,764,126
Ensembl chr 5:80,753,618...80,764,123 		JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SNRNP70 mRNA CTD PMID:15477007 NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:104,992,442...105,012,851 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SOD1 mRNA CTD PMID:15477007 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO bathocuproine sulfonate promotes the reaction [SP1 protein results in increased expression of SLC31A1 mRNA] CTD PMID:18483225 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513 		JBrowse link
G Srgn serglycin multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SRGN mRNA CTD PMID:15477007 NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327 		JBrowse link
G Srpra SRP receptor subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA] CTD PMID:15477007 NCBI chr 8:41,818,199...41,824,292
Ensembl chr 8:41,818,229...41,824,280 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]] CTD PMID:11006087 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA] CTD PMID:15477007 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein] CTD PMID:11964141 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpo thyroid peroxidase multiple interactions EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of TPO mRNA] CTD PMID:11108245 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793 		JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]] CTD PMID:15477007 NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:38,619,506...38,636,264 		JBrowse link
G Tyr tyrosinase multiple interactions ISO bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] CTD PMID:11092760 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] CTD PMID:15477007 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
G Ube2l6 ubiquitin-conjugating enzyme E2L 6 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBE2L6 mRNA CTD PMID:15477007 NCBI chr 3:90,279,705...90,294,721
Ensembl chr 3:90,279,668...90,294,717 		JBrowse link
G Ubl4a ubiquitin-like 4A multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBL4A mRNA CTD PMID:15477007 NCBI chr  X:157,302,528...157,305,380
Ensembl chr  X:157,304,254...157,305,380 		JBrowse link
G Vim vimentin multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA] CTD PMID:15477007 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
bromocresol purple term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Bromcresol Purple binds to and results in decreased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
bromophenol blue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO Bromphenol Blue inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
bromothymol blue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Bromthymol Blue binds to and results in increased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Bromthymol Blue binds to and results in decreased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
Congo Red term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
affects binding 		EXP
ISO 		Congo Red inhibits the reaction [APP protein binds to APP protein]
Congo Red binds to APP protein 		CTD PMID:17323972 PMID:17406451 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Prnp prion protein decreases expression ISO Congo Red results in decreased expression of PRNP protein alternative form CTD PMID:11994310 NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436 		JBrowse link
dodecylbenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO dodecylbenzenesulfonic acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
famphur term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 affects activity ISO famophos metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
p-chloromercuribenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 decreases activity ISO 4-Chloromercuribenzenesulfonate results in decreased activity of AKR1B10 protein CTD PMID:23261715 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 decreases activity EXP 4-Chloromercuribenzenesulfonate results in decreased activity of AKR1B7 protein CTD PMID:23261715 NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909 		JBrowse link
G Aqp1 aquaporin 1 decreases activity ISO 4-Chloromercuribenzenesulfonate results in decreased activity of AQP1 protein CTD PMID:11468359 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504 		JBrowse link
G Cldn2 claudin 2 decreases activity ISO 4-Chloromercuribenzenesulfonate results in decreased activity of CLDN2 protein mutant form CTD PMID:19690347 NCBI chr  X:108,248,383...108,258,847
Ensembl chr  X:108,237,676...108,262,377 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO 4-Chloromercuribenzenesulfonate inhibits the reaction [SLC16A1 protein results in increased uptake of Lactic Acid] CTD PMID:15804185 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO 4-Chloromercuribenzenesulfonate inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:31,040,017...31,051,670 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 increases activity ISO 4-Chloromercuribenzenesulfonate results in increased activity of TRPC5 protein CTD PMID:21984481 NCBI chr  X:112,742,828...113,027,638
Ensembl chr  X:112,742,828...113,027,638 		JBrowse link
phenol red term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 affects export EXP ABCC2 protein affects the export of Phenolsulfonphthalein CTD PMID:15618741 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Actbl2 actin, beta-like 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of ACTBL2 protein CTD PMID:31629898 NCBI chr 2:44,591,391...44,594,138
Ensembl chr 2:44,591,391...44,594,138 		JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of AFAP1 protein CTD PMID:31629898 NCBI chr14:78,967,961...79,081,032
Ensembl chr14:78,967,961...79,080,939 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Phenolsulfonphthalein results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:17203231 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Ankrd17 ankyrin repeat domain 17 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANKRD17 protein CTD PMID:31629898 NCBI chr14:18,007,342...18,145,980
Ensembl chr14:18,008,859...18,145,980 		JBrowse link
G Anxa11 annexin A11 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANXA11 protein CTD PMID:31629898 NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839 		JBrowse link
G Anxa3 annexin A3 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANXA3 protein CTD PMID:31629898 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849 		JBrowse link
G Arcn1 archain 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ARCN1 protein CTD PMID:31629898 NCBI chr 8:53,954,401...53,979,005
Ensembl chr 8:53,954,404...53,979,005 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ASAP1 protein CTD PMID:31629898 NCBI chr 7:97,675,354...97,982,523
Ensembl chr 7:97,675,354...97,982,024 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of BCL2L1 protein CTD PMID:31629898 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CDH1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in decreased expression of CDH1 protein CTD PMID:31629898 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CDH2 protein CTD PMID:31629898 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cfl2 cofilin 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CFL2 protein CTD PMID:31629898 NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:78,090,843...78,094,888 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CKAP5 protein CTD PMID:31629898 NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049 		JBrowse link
G Ctcf CCCTC-binding factor multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CTCF protein CTD PMID:31629898 NCBI chr19:50,431,478...50,481,013
Ensembl chr19:50,431,689...50,481,012 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CTNNB1 protein CTD PMID:31629898 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctnnbl1 catenin, beta like 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CTNNBL1 protein CTD PMID:31629898 NCBI chr 3:166,807,899...166,968,932
Ensembl chr 3:166,807,858...166,968,931 		JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CTNND1 protein CTD PMID:31629898 NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:90,090,564...90,141,189 		JBrowse link
G Dnm1 dynamin 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DNM1 protein CTD PMID:31629898 NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:36,002,064...36,046,289 		JBrowse link
G Dnm2 dynamin 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of DNM2 protein CTD PMID:31629898 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:28,254,529...28,336,295 		JBrowse link
G Dsg2 desmoglein 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DSG2 protein CTD PMID:31629898 NCBI chr18:12,121,287...12,179,590
Ensembl chr18:12,121,181...12,179,590 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DYNC1LI1 protein CTD PMID:31629898 NCBI chr 8:123,254,823...123,288,496
Ensembl chr 8:123,254,859...123,289,167 		JBrowse link
G Dynlt1 dynein light chain Tctex-type 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DYNLT1 protein CTD PMID:31629898 NCBI chr 1:49,292,093...49,299,051
Ensembl chr 1:49,282,243...49,298,951 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of EIF2B4 protein CTD PMID:31629898 NCBI chr 6:30,903,148...30,908,803
Ensembl chr 6:30,903,219...30,908,800 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of EIF4A3 protein CTD PMID:31629898 NCBI chr10:105,047,567...105,057,561
Ensembl chr10:105,047,568...105,058,207 		JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of ESRRG protein CTD PMID:31629898 NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of G3BP1 protein CTD PMID:31629898 NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931 		JBrowse link
G Gdi2 GDP dissociation inhibitor 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of GDI2 protein CTD PMID:31629898 NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO [Phenolsulfonphthalein co-treated with bisphenol A deficiency] results in increased expression of GJA1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in decreased expression of GJA1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of GJA1 protein CTD PMID:31629898 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gna13 G protein subunit alpha 13 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of GNA13 protein CTD PMID:31629898 NCBI chr10:94,837,271...94,870,290
Ensembl chr10:94,836,444...94,874,968 		JBrowse link
G Gnai1 G protein subunit alpha i1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of GNAI1 protein CTD PMID:31629898 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198 		JBrowse link
G H2ac12 H2A clustered histone 12 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of H2AC12 protein CTD PMID:31629898 NCBI chr17:47,182,193...47,182,658 JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of IQGAP2 protein CTD PMID:31629898 NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649 		JBrowse link
G Kif5b kinesin family member 5B multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of KIF5B protein CTD PMID:31629898 NCBI chr17:56,185,386...56,222,990
Ensembl chr17:56,185,380...56,223,008 		JBrowse link
G Kpna3 karyopherin subunit alpha 3 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KPNA3 protein CTD PMID:31629898 NCBI chr15:39,712,375...39,786,127
Ensembl chr15:39,712,381...39,786,319 		JBrowse link
G Krt31 keratin 31 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KRT31 protein CTD PMID:31629898 NCBI chr10:85,479,533...85,483,300
Ensembl chr10:85,479,796...85,483,300 		JBrowse link
G Krt34 keratin 34 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KRT34 protein CTD PMID:31629898 NCBI chr10:85,470,391...85,474,501
Ensembl chr10:85,470,391...85,474,501 		JBrowse link
G Krt84 keratin 84 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KRT84 protein CTD PMID:31629898 NCBI chr 7:134,527,787...134,535,608
Ensembl chr 7:134,527,787...134,535,608 		JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of LSG1 protein CTD PMID:31629898 NCBI chr11:83,648,757...83,673,431
Ensembl chr11:83,648,772...83,673,878 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases oxidation 		ISO [MPO protein results in increased oxidation of Phenolsulfonphthalein] which results in decreased abundance of Glutathione; [MPO protein results in increased oxidation of Phenolsulfonphthalein] which results in increased abundance of Glutathione Disulfide; MPO protein promotes the reaction [Phenolsulfonphthalein binds to Halogens]; Phenolsulfonphthalein promotes the reaction [MPO protein promotes the reaction [chlorodimedone binds to Chlorine]] CTD PMID:31288001 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Myh1 myosin heavy chain 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of MYH1 protein CTD PMID:31629898 NCBI chr10:52,384,810...52,408,698
Ensembl chr10:52,384,908...52,409,047 		JBrowse link
G Myo10 myosin X multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of MYO10 protein CTD PMID:31629898 NCBI chr 2:77,831,532...78,036,137
Ensembl chr 2:77,831,532...78,036,137 		JBrowse link
G Myo5c myosin VC multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of MYO5C protein CTD PMID:31629898 NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996 		JBrowse link
G Nemf nuclear export mediator factor multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NEMF protein CTD PMID:31629898 NCBI chr 6:93,527,690...93,571,863
Ensembl chr 6:93,527,704...93,571,863 		JBrowse link
G Nfib nuclear factor I/B multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NFIB protein CTD PMID:31629898 NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NIFK protein CTD PMID:31629898 NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561 		JBrowse link
G Noc3l NOC3-like DNA replication regulator multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NOC3L protein CTD PMID:31629898 NCBI chr 1:245,969,179...245,997,761
Ensembl chr 1:245,969,179...245,997,708 		JBrowse link
G Pcbp1 poly(rC) binding protein 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of PCBP1 protein CTD PMID:31629898 NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:120,529,172...120,539,111 		JBrowse link
G Pgr progesterone receptor increases expression ISO Phenolsulfonphthalein results in increased expression of PGR protein CTD PMID:3458212 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Phf14 PHD finger protein 14 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of PHF14 protein CTD PMID:31629898 NCBI chr 4:40,975,897...41,162,043
Ensembl chr 4:40,975,439...41,162,043 		JBrowse link
G Phf5a PHD finger protein 5A multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of PHF5A protein CTD PMID:31629898 NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO Phenolsulfonphthalein results in increased expression of POU5F1 mRNA CTD PMID:22132214 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598 		JBrowse link
G Rab12 RAB12, member RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB12 protein CTD PMID:31629898 NCBI chr 9:113,927,119...113,953,722
Ensembl chr 9:113,927,119...113,953,695 		JBrowse link
G Rab14 RAB14, member RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB14 protein CTD PMID:31629898 NCBI chr 3:38,899,430...38,920,572
Ensembl chr 3:38,901,400...38,912,273 		JBrowse link
G Rab24 RAB24, member RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB24 protein CTD PMID:31629898 NCBI chr17:9,313,593...9,315,675
Ensembl chr17:9,313,593...9,316,575 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB27A protein CTD PMID:31629898 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262 		JBrowse link
G Rab27b RAB27B, member RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB27B protein CTD PMID:31629898 NCBI chr18:65,870,230...66,069,597
Ensembl chr18:65,876,342...66,067,700 		JBrowse link
G Rab5c RAB5C, member RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RAB5C protein CTD PMID:31629898 NCBI chr10:86,142,872...86,166,449
Ensembl chr10:86,142,873...86,166,449 		JBrowse link
G Rala RAS like proto-oncogene A multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RALA protein CTD PMID:31629898 NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733 		JBrowse link
G Ralb RAS like proto-oncogene B multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RALB protein CTD PMID:31629898 NCBI chr13:33,140,834...33,176,997
Ensembl chr13:33,140,835...33,176,998 		JBrowse link
G Rap2b RAP2B, member of RAS oncogene family multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAP2B protein CTD PMID:31629898 NCBI chr 2:147,749,387...147,749,938
Ensembl chr 2:147,748,791...147,755,549 		JBrowse link
G Rasip1 Ras interacting protein 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RASIP1 protein CTD PMID:31629898 NCBI chr 1:105,233,599...105,246,028
Ensembl chr 1:105,233,599...105,246,028 		JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RMDN3 protein CTD PMID:31629898 NCBI chr 3:126,579,811...126,601,016
Ensembl chr 3:126,579,812...126,600,418 		JBrowse link
G Rras RAS related multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RRAS protein CTD PMID:31629898 NCBI chr 1:104,637,061...104,640,841
Ensembl chr 1:104,634,951...104,640,841 		JBrowse link
G Rrp9 ribosomal RNA processing 9, U3 small nucleolar RNA binding protein multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RRP9 protein CTD PMID:31629898 NCBI chr 8:115,995,119...116,004,832
Ensembl chr 8:115,996,169...116,004,824 		JBrowse link
G Scamp3 secretory carrier membrane protein 3 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of SCAMP3 protein CTD PMID:31629898 NCBI chr 2:176,880,873...176,886,750
Ensembl chr 2:176,880,909...176,886,748 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [Phenolsulfonphthalein co-treated with bisphenol A deficiency] results in increased expression of SNAI1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in decreased expression of SNAI1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of SNAI1 protein CTD PMID:31629898 NCBI chr 3:176,667,476...176,671,965 JBrowse link
G Srp14 signal recognition particle 14 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of SRP14 protein CTD PMID:31629898 NCBI chr 3:125,896,128...125,899,819
Ensembl chr 3:125,896,556...125,899,819 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of SSBP1 protein CTD PMID:31629898 NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700 		JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions EXP Phenolsulfonphthalein inhibits the reaction [Oleic Acid results in increased expression of TBXA2R mRNA] CTD PMID:11263294 NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:9,034,108...9,038,905 		JBrowse link
G Tln1 talin 1 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of TLN1 protein CTD PMID:31629898 NCBI chr 5:62,583,730...62,613,687
Ensembl chr 5:62,583,731...62,613,687 		JBrowse link
G Tuba1a tubulin, alpha 1A multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of TUBA1A protein CTD PMID:31629898 NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035 		JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of TUBB3 protein CTD PMID:31629898 NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740 		JBrowse link
G Utp3 UTP3, small subunit processome component multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of UTP3 protein CTD PMID:31629898 NCBI chr14:19,799,766...19,801,420
Ensembl chr14:19,796,215...19,801,446 		JBrowse link
G Utp6 UTP6 small subunit processome component multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of UTP6 protein CTD PMID:31629898 NCBI chr10:65,395,253...65,425,928
Ensembl chr10:65,395,253...65,425,928 		JBrowse link
G Vim vimentin multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of VIM protein CTD PMID:31629898 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Ybx3 Y box binding protein 3 multiple interactions ISO [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of YBX3 protein CTD PMID:31629898 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691 		JBrowse link
S3I-201 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak2 Janus kinase 2 multiple interactions ISO S3I-201 inhibits the reaction [Rapamycin increases phosphorylation of JAK2 protein in lung epithelium] RGD PMID:30755242 RGD:149735343 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
suramin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Suramin inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]] CTD PMID:12044622 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Casp1 caspase 1 multiple interactions EXP Suramin inhibits the reaction [Glucose results in increased activity of CASP1 protein] CTD PMID:21832250 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of CASP3]; Suramin inhibits the reaction [Clodronic Acid results in increased expression of CASP3] CTD PMID:19448140 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression ISO Suramin results in increased expression of CHRNA7 protein CTD PMID:23516405 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Suramin inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of CREB1 protein] CTD PMID:18612546 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Suramin results in decreased activity of CYP1A2 protein CTD PMID:11124226 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Suramin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] CTD PMID:22167199 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Suramin results in decreased activity of CYP2C19 protein CTD PMID:11124226 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of EGFR protein] CTD PMID:9710602 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Suramin results in increased expression of FGF2 CTD PMID:8394679 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf5 fibroblast growth factor 5 increases expression ISO Suramin results in increased expression of FGF5 CTD PMID:8394679 NCBI chr14:11,627,906...11,650,243
Ensembl chr14:11,627,906...11,650,243 		JBrowse link
G Fgf7 fibroblast growth factor 7 affects localization
multiple interactions 		ISO Suramin affects the localization of FGF7 protein
Suramin inhibits the reaction [FGF7 protein binds to FGFR2 protein] 		CTD PMID:15733146 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions ISO Suramin inhibits the reaction [FGF7 protein binds to FGFR2 protein] CTD PMID:15733146 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO Suramin inhibits the reaction [Poly I-C results in decreased expression of FMR1 protein] CTD PMID:23516405 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:152,284,841...152,322,675 		JBrowse link
G Gusb glucuronidase, beta decreases activity EXP suramin decreases activity of beta-glucuronidase in rat spleen, kidney, and lung RGD PMID:2879381 RGD:42724461 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase decreases activity ISO Suramin results in decreased activity of HPGDS protein CTD PMID:25603235 NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases activity 		ISO Suramin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of IL10 protein]
Suramin results in decreased activity of IL10 protein 		CTD PMID:15914193 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12b interleukin 12B increases expression ISO Suramin results in increased expression of IL12B protein CTD PMID:15914193 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; Suramin inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein]; Suramin inhibits the reaction [Uridine Triphosphate results in increased expression of IL6 protein]
Suramin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] 		CTD PMID:24793913 PMID:24849676 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Lmna lamin A/C multiple interactions ISO Suramin inhibits the reaction [LMNA protein binds to and results in increased activity of SIRT1 protein] CTD PMID:23217256 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP 		Suramin inhibits the reaction [arsenic acid results in increased activity of MAPK1 protein]; Suramin inhibits the reaction [arsenite results in increased activity of MAPK1 protein]; Suramin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Suramin inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of MAPK1 protein]
Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Suramin inhibits the reaction [2,6-di-tert-butyl-4-hydroperoxy-4-methyl-2,5-cyclohexadienone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Suramin inhibits the reaction [Poly I-C results in decreased phosphorylation of MAPK1 protein] 		CTD PMID:8758915 PMID:9710602 PMID:14674888 PMID:15930183 PMID:18612546 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP 		Suramin inhibits the reaction [arsenic acid results in increased activity of MAPK3 protein]; Suramin inhibits the reaction [arsenite results in increased activity of MAPK3 protein]; Suramin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Suramin inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of MAPK3 protein]
Suramin inhibits the reaction [Poly I-C results in decreased phosphorylation of MAPK3 protein]
Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of MAPK3 protein] 		CTD PMID:9710602 PMID:14674888 PMID:15930183 PMID:18612546 PMID:23516405 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G P2rx1 purinergic receptor P2X 1 affects binding EXP Suramin binds to P2rx1 protein RGD PMID:12237343 RGD:727431 NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164 		JBrowse link
G P2rx2 purinergic receptor P2X 2 affects activity EXP suramin affects activity of rat P2x2 receptor in transfected glial cells RGD PMID:16388598 RGD:1642662 NCBI chr12:51,999,107...52,002,627
Ensembl chr12:51,999,372...52,002,627 		JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions EXP Suramin inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein] CTD PMID:23666265 NCBI chr 3:90,487,506...90,531,315
Ensembl chr 3:90,487,506...90,531,794 		JBrowse link
G P2rx5 purinergic receptor P2X 5 affects transport EXP Suramin affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr10:58,276,329...58,291,108
Ensembl chr10:58,276,257...58,287,935 		JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein] CTD PMID:23516405 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases activity
multiple interactions 		EXP
ISO 		Suramin results in decreased activity of P2RY2 protein
Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RY2 protein] 		CTD PMID:15654852 PMID:23516405 NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:164,759,213...164,781,852 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO JTE 013 promotes the reaction [Suramin inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]]; Suramin inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]]; Suramin inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]; Suramin promotes the reaction [JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]] CTD PMID:18612546 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions
increases expression 		EXP
ISO 		Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of SHC1 protein]
Suramin results in increased expression of SHC1 mRNA; Suramin results in increased expression of SHC1 protein 		CTD PMID:9710602 PMID:21778425 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO Suramin inhibits the reaction [LMNA protein binds to and results in increased activity of SIRT1 protein]; Suramin results in decreased activity of [SIRT1 protein results in decreased acetylation of TP53 protein]
[Suramin results in decreased activity of SIRT1 protein] which results in decreased susceptibility to resveratrol 		CTD PMID:18482975 PMID:23217256 PMID:24252177 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions EXP Suramin inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein] CTD PMID:23666265 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Suramin results in increased expression of TNF protein CTD PMID:15914193 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Suramin results in decreased activity of [SIRT1 protein results in decreased acetylation of TP53 protein] CTD PMID:18482975 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vdr vitamin D receptor multiple interactions ISO Suramin inhibits the reaction [Estradiol results in increased expression of VDR protein] CTD PMID:15930183 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
WIN 55212-2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of ABCA2 mRNA CTD PMID:12237329 NCBI chr 3:28,642,660...28,662,689
Ensembl chr 3:28,642,758...28,662,681 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects activity ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the activity of ABCG2 protein CTD PMID:30083819 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in decreased phosphorylation of ACACA protein] CTD PMID:27324222 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression 		ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; JTE 907 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone analog results in decreased expression of ACTA2 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of ACTA2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] 		CTD PMID:31901889 PMID:31991773 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 multiple interactions
decreases activity 		ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]; JTE 907 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]; JTE 907 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of ADAMTS4 protein]; JTE 907 promotes the reaction [SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]]; JTE 907 promotes the reaction [SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of ADAMTS4 protein]]; SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]; SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of ADAMTS4 protein] CTD PMID:27082728 NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514 		JBrowse link
G Adora2a adenosine A2a receptor decreases response to substance EXP ADORA2A protein results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone CTD PMID:26526685 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions 		ISO
EXP 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of AKT1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of AKT1 protein; CNR2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of AKT1 protein] 		CTD PMID:12734338 PMID:20619260 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of APAF1 protein CTD PMID:30776504 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA] CTD PMID:21350020 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Arg1 arginase 1 multiple interactions
affects expression 		ISO AM6545 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of ARG1 mRNA] CTD PMID:30184259 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of ARHGDIA mRNA CTD PMID:12237329 NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; GRK2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with CNR2 protein] affects the localization of ARRB2 protein CTD PMID:31024316 PMID:31901889 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of BCL2 protein CTD PMID:26967640 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Becn1 beclin 1 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of BECN1 protein CTD PMID:30776504 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Casp3 caspase 3 decreases cleavage
increases cleavage 		ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased cleavage of CASP3 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased cleavage of CASP3 protein 		CTD PMID:26967640 PMID:30776504 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 decreases cleavage ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased cleavage of CASP7 protein CTD PMID:30776504 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 decreases cleavage ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased cleavage of CASP8 protein CTD PMID:30776504 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity 		ISO AM 281 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CASP9 protein] CTD PMID:28495606 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CCND2 protein CTD PMID:26967640 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CCT7 mRNA CTD PMID:12237329 NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973 		JBrowse link
G Cdk14 cyclin-dependent kinase 14 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of CDK14 mRNA CTD PMID:12237329 NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of CITED2 mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of CITED2 protein CTD PMID:12237329 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782 		JBrowse link
G Cldn1 claudin 1 multiple interactions ISO [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein CTD PMID:27920472 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression
affects binding
increases activity
increases degradation
increases response to substance
affects response to substance
decreases expression
affects localization 		ISO
EXP 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR1 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of MAPK1 protein]; CNR1 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of CNR1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to CNR1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased degradation of CNR1 protein
CNR1 protein results in increased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone
CNR1 protein mutant form affects the susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the localization of CNR1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein; [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 mRNA]; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein; 6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole promotes the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to CNR1 protein]; [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] which results in increased expression of FOS protein; CNRIP1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the localization of CNR1 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1 protein 		CTD PMID:8526880 PMID:10871313 PMID:12421626 PMID:12560108 PMID:16157695 More... NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Cnr2 cannabinoid receptor 2 affects response to substance
increases expression
multiple interactions
increases activity
affects binding 		ISO
EXP 		CNR2 gene SNP affects the susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of CNR2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR2 protein; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with CNR2 protein] affects the localization of ARRB2 protein; Dronabinol analog inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to CNR2 protein]; GRK2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]]; ridaifen-B inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR2 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR2 protein; [SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; CNR2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; CNR2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein] 		CTD PMID:10688601 PMID:12734338 PMID:17572696 PMID:20124950 PMID:21281698 More... NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961 		JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 multiple interactions ISO CNRIP1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the localization of CNR1 protein] CTD PMID:27513693 NCBI chr14:95,664,435...95,707,062
Ensembl chr14:95,664,774...95,694,371 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of CREB1 protein CTD PMID:26289146 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Ctsd cathepsin D increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of CTSD protein CTD PMID:30776504 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression 		ISO Acetylcysteine inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of DDIT3 mRNA]; methyl-beta-cyclodextrin inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of DDIT3 mRNA] CTD PMID:30502353 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of EFS mRNA CTD PMID:12237329 NCBI chr15:32,362,401...32,374,490
Ensembl chr15:32,361,843...32,371,743 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation 		ISO RTKI cpd inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of EGFR protein] CTD PMID:20619260 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of EIF4B mRNA CTD PMID:12237329 NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064 		JBrowse link
G Eno2 enolase 2 decreases expression
multiple interactions 		ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of ENO2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in increased expression of ENO2 protein] 		CTD PMID:27324222 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased expression of F3 mRNA] CTD PMID:27556861 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
affects expression 		ISO
EXP 		[Acetaminophen co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of FAAH mRNA
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of FAAH mRNA
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of FAAH mRNA 		CTD PMID:30165669 PMID:32833042 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] which results in increased expression of FOS protein CTD PMID:12560108 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gck glucokinase increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of GCK mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of GCK protein CTD PMID:12237329 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [amyloid beta-protein (25-35) affects the localization of GJA1 protein] CTD PMID:27757991 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gphn gephyrin multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein] CTD PMID:32312805 NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:102,687,423...103,216,674 		JBrowse link
G Gpr55 G protein-coupled receptor 55 affects response to substance ISO GPR55 protein affects the susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone CTD PMID:31877572 NCBI chr 9:94,037,748...94,081,426
Ensembl chr 9:94,036,162...94,088,707 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of GRIA1 protein CTD PMID:32312805 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of GRIA2 protein CTD PMID:32312805 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein] CTD PMID:28092019 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO GRK2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Hdac6 histone deacetylase 6 multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in decreased expression of HDAC6 protein] CTD PMID:32312805 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Hspb3 heat shock protein family B (small) member 3 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of HSPB3 mRNA CTD PMID:12237329 NCBI chr 2:47,028,451...47,029,165
Ensembl chr 2:47,024,757...47,029,373 		JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Cocaine] results in decreased phosphorylation of HTATSF1 protein CTD PMID:32312805 NCBI chr  X:139,972,742...139,986,923
Ensembl chr  X:139,972,742...139,986,923 		JBrowse link
G Ifng interferon gamma multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; [Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]; Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA] CTD PMID:11520904 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP
ISO 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein] 		CTD PMID:31732924 PMID:32385136 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased abundance of N-palmitoylsphingosine]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased expression of F3 mRNA]; JTE 907 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]; JTE 907 promotes the reaction [SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]]; SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [amyloid beta-protein (25-35) results in increased secretion of IL1B protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Carbon Monoxide results in increased expression of IL1B protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Carbon Monoxide results in increased expression of IL1B protein]] 		CTD PMID:27082728 PMID:27556861 PMID:27757991 PMID:31732924 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL1RL1 protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL1RL1 protein]] CTD PMID:31732924 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il33 interleukin 33 multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]] CTD PMID:31732924 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP [Carbon Monoxide co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in increased expression of IL4 protein; iodopravadoline inhibits the reaction [[Carbon Monoxide co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in increased expression of IL4 protein] CTD PMID:31732924 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in decreased phosphorylation of ACACA protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in decreased phosphorylation of PRKAA1 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in increased expression of ENO2 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in increased expression of TUBB3 protein] 		CTD PMID:21350020 PMID:27324222 PMID:27920472 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased phosphorylation of and results in decreased activity of KDR protein; fumonisin B1 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased phosphorylation of and results in decreased activity of KDR protein] CTD PMID:15313899 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of MAP2 mRNA CTD PMID:12237329 NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation 		ISO
EXP 		CNR1 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of MAPK1 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased expression of MAPK1 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of MAPK1 protein 		CTD PMID:8526880 PMID:12657697 PMID:12734338 PMID:20619260 PMID:32312805 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
multiple interactions
increases phosphorylation 		ISO
EXP 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of MAPK3 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased expression of MAPK3 protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR2 protein affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of MAPK3 protein
CNR1 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of MAPK3 protein] 		CTD PMID:8526880 PMID:12657697 PMID:12734338 PMID:20619260 PMID:32312805 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of MAPK8 protein CTD PMID:20619260 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of MAPK9 protein CTD PMID:20619260 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MAPT mRNA CTD PMID:12237329 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of MAT2A mRNA CTD PMID:12237329 NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645 		JBrowse link
G Mbp myelin basic protein multiple interactions
increases expression 		EXP Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MBP protein]; SR 144528 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MBP protein] CTD PMID:17880390 NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174 		JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone CTD PMID:21911610 NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
decreases expression
multiple interactions 		ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of MMP2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of MMP2 protein
JTE 907 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone analog results in decreased expression of MMP2 protein] 		CTD PMID:29883990 PMID:30776504 PMID:31991773 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of MMP9 protein CTD PMID:30776504 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Morf4l1 mortality factor 4 like 1 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of MORF4L1 mRNA CTD PMID:12237329 NCBI chr 8:99,522,801...99,544,432
Ensembl chr 8:99,500,898...99,544,331 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:27920472 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Carbon Monoxide] results in increased expression of MRC1 protein; iodopravadoline inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Carbon Monoxide] results in increased expression of MRC1 protein] CTD PMID:31732924 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MYC mRNA CTD PMID:12237329 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of NAPEPLD mRNA CTD PMID:32833042 NCBI chr 4:14,251,591...14,291,010
Ensembl chr 4:14,252,692...14,291,014 		JBrowse link
G Ndrg4 NDRG family member 4 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of NDRG4 mRNA CTD PMID:12237329 NCBI chr19:9,357,470...9,393,465
Ensembl chr19:9,357,470...9,392,972 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of NEDD4L mRNA CTD PMID:12237329 NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases localization EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased localization of NFATC4 protein CTD PMID:16849427 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA; Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA] CTD PMID:11520904 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Npas2 neuronal PAS domain protein 2 multiple interactions EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Cocaine results in increased splicing of NPAS2 mRNA] CTD PMID:32312805 NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037 		JBrowse link
G Ntn1 netrin 1 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of NTN1 mRNA CTD PMID:12237329 NCBI chr10:53,398,852...53,597,595
Ensembl chr10:53,398,852...53,584,060 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Acetaminophen co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NTRK2 mRNA CTD PMID:30165669 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628 		JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of PACSIN1 mRNA CTD PMID:12237329 NCBI chr20:5,719,929...5,769,492
Ensembl chr20:5,721,311...5,767,109 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of PARP1 protein CTD PMID:30776504 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of PERP mRNA CTD PMID:12237329 NCBI chr 1:15,361,784...15,374,230
Ensembl chr 1:15,361,778...15,374,687 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of PPARA protein CTD PMID:17906680 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of PPP2R1A mRNA CTD PMID:12237329 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in decreased phosphorylation of PRKAA1 protein] CTD PMID:27324222 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
affects expression 		EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of PTEN mRNA
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of PTEN mRNA 		CTD PMID:32833042 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of PTGDS mRNA CTD PMID:12237329 NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978 		JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of PTPRN mRNA CTD PMID:12237329 NCBI chr 9:84,189,676...84,205,364
Ensembl chr 9:84,189,676...84,204,850 		JBrowse link
G Rfc1 replication factor C subunit 1 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of RFC1 mRNA CTD PMID:12237329 NCBI chr14:43,319,768...43,395,028
Ensembl chr14:43,319,935...43,395,026 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of RGS7 mRNA CTD PMID:27578457 NCBI chr13:89,511,492...89,941,082
Ensembl chr13:89,511,150...89,940,987 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of RIPK1 protein CTD PMID:30776504 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Rtn3 reticulon 3 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of RTN3 mRNA CTD PMID:12237329 NCBI chr 1:214,041,838...214,098,644
Ensembl chr 1:214,041,838...214,109,638 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of S1PR3 mRNA CTD PMID:12237329 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197 		JBrowse link
G Sdc1 syndecan 1 multiple interactions
decreases expression 		ISO JTE 907 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of SDC1 protein]; JTE 907 promotes the reaction [SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]]; JTE 907 promotes the reaction [SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of ADAMTS4 protein]]; SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL1B protein results in increased activity of ADAMTS4 protein]]; SDC1 protein inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased activity of ADAMTS4 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of SDC1 mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of SDC1 protein 		CTD PMID:27082728 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500 		JBrowse link
G Serpine2 serpin family E member 2 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of SERPINE2 mRNA CTD PMID:12237329 NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202 		JBrowse link
G Slc12a5 solute carrier family 12 member 5 affects expression EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC12A5 mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC12A5 protein CTD PMID:31653479 NCBI chr 3:174,115,833...174,155,112
Ensembl chr 3:174,115,833...174,155,112 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases expression EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of SLC1A1 protein CTD PMID:17631920 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of SLC1A2 protein CTD PMID:17631920 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Isoproterenol results in increased expression of SLC6A1 protein] CTD PMID:30170018 NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:149,004,635...149,037,839 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects expression
multiple interactions 		EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC6A3 mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC6A3 protein
AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC6A3 mRNA] 		CTD PMID:29113897 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962 		JBrowse link
G Smn1 survival of motor neuron 1, telomeric decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of SMN1 mRNA CTD PMID:12237329 NCBI chr 2:33,224,115...33,235,162
Ensembl chr 2:33,224,095...33,235,162 		JBrowse link
G Syp synaptophysin multiple interactions ISO [Acetaminophen co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of SYP mRNA CTD PMID:30165669 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:17,521,348...17,536,984 		JBrowse link
G Tagln3 transgelin 3 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of TAGLN3 mRNA CTD PMID:12237329 NCBI chr11:68,562,482...68,576,058
Ensembl chr11:68,562,338...68,576,051 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] 		CTD PMID:31901889 PMID:31991773 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
affects expression 		EXP
ISO 		AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH protein 		CTD PMID:28092019 PMID:29113897 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Carbon Monoxide results in increased expression of TNF protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Carbon Monoxide results in increased expression of TNF protein]]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [amyloid beta-protein (25-35) results in increased secretion of TNF protein]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein] 		CTD PMID:12509806 PMID:27757991 PMID:27920472 PMID:31732924 PMID:31901889 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of TP53 protein CTD PMID:30776504 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Traf5 TNF receptor-associated factor 5 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of TRAF5 mRNA CTD PMID:12237329 NCBI chr13:106,100,921...106,149,724
Ensembl chr13:106,103,291...106,149,707 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of TRIB3 protein CTD PMID:16818650 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802 		JBrowse link
G Trim8 tripartite motif-containing 8 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of TRIM8 mRNA CTD PMID:12237329 NCBI chr 1:255,311,039...255,325,937
Ensembl chr 1:255,310,457...255,325,937 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases response to substance 		EXP
ISO 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of TRPA1 protein; TRPA1 promotes the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased abundance of Calcium]
TRPA1 results in increased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone 		CTD PMID:18234885 PMID:18550765 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
decreases phosphorylation 		EXP (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of TRPV1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased phosphorylation of TRPV1 protein 		CTD PMID:16849427 PMID:18550765 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression
multiple interactions 		ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of TUBB3 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [IL6 protein results in increased expression of TUBB3 protein] 		CTD PMID:27324222 NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein; fumonisin B1 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein]; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein]; SR 144528 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein] 		CTD PMID:15313899 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vps26c VPS26 endosomal protein sorting factor C increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of VPS26C mRNA CTD PMID:12237329 NCBI chr11:47,283,764...47,311,105
Ensembl chr11:47,262,071...47,311,045 		JBrowse link
G Wdr47 WD repeat domain 47 decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of WDR47 mRNA CTD PMID:12237329 NCBI chr 2:198,914,977...198,975,844
Ensembl chr 2:198,914,940...198,975,841 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of XIAP protein CTD PMID:30776504 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
G Znrf1 zinc and ring finger 1 increases expression ISO (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of ZNRF1 mRNA CTD PMID:12237329 NCBI chr19:56,403,816...56,490,901
Ensembl chr19:56,405,728...56,490,881 		JBrowse link
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  CHEBI ontology 20849
    chemical entity 20860
      group 20803
        organic group 19539
          organic univalent group 19170
            organyl group 19170
              hydrocarbyl group 4686
                aryl group 769
                  arenesulfonic acid + 696
                  biphenyl-4-yl group + 0
                  naphthyl group + 118
                  phenyl group + 0
                  pyrenyl group + 0
                  tolyl group + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20849
    subatomic particle 20847
      composite particle 20860
        hadron 20847
          baryon 20860
            nucleon 20847
              atomic nucleus 20847
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20565
                        hydrogen molecular entity 20549
                          hydrides 19684
                            organic hydride 19084
                              organic fundamental parent 19071
                                hydrocarbon 18736
                                  cyclic hydrocarbon 17326
                                    arene 17315
                                      aryl group 769
                                        arenesulfonic acid + 696
                                        biphenyl-4-yl group + 0
                                        naphthyl group + 118
                                        phenyl group + 0
                                        pyrenyl group + 0
                                        tolyl group + 0
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