CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: scandium group element atom
Accession: CHEBI:33335
browse the term
Synonyms: exact_synonym: group 3 elements
related_synonym: scandium group element; scandium group elements
G
Cacna1g
calcium voltage-gated channel subunit alpha1 G
multiple interactions
ISO
Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
G
Camk4
calcium/calmodulin-dependent protein kinase IV
decreases phosphorylation
EXP
Lanthanum results in decreased phosphorylation of CAMK4 protein
CTD
PMID:21695898
NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
G
Casr
calcium-sensing receptor
multiple interactions
ISO
Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Spermine binds to and results in increased activity of CASR protein]
CTD
PMID:17041782 PMID:21562303
NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
G
Chrm1
cholinergic receptor, muscarinic 1
multiple interactions
ISO
Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
CTD
PMID:18316702
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
G
Creb1
cAMP responsive element binding protein 1
decreases phosphorylation
EXP
Lanthanum results in decreased phosphorylation of CREB1 protein
CTD
PMID:21695898
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
G
Drd1
dopamine receptor D1
multiple interactions
EXP
Lanthanum inhibits the reaction [SCH 23390 binds to DRD1 protein]
CTD
PMID:9109525
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
G
Drd2
dopamine receptor D2
multiple interactions
EXP
Lanthanum inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]
CTD
PMID:9109525
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Egr1
early growth response 1
decreases expression
EXP
Lanthanum results in decreased expression of EGR1 mRNA
CTD
PMID:21695898
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
Lanthanum results in decreased expression of FOS mRNA
CTD
PMID:21695898
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
Lanthanum binds to and results in increased expression of HSPA5 protein
CTD
PMID:18773883
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Igf2
insulin-like growth factor 2
multiple interactions
ISO
Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]
CTD
PMID:2442157
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Ins2
insulin 2
decreases response to substance
ISO
Lanthanum results in decreased susceptibility to INS protein
CTD
PMID:22031853
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
Lanthanum results in decreased expression of JUN mRNA
CTD
PMID:21695898
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Lep
leptin
multiple interactions
ISO
Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]
CTD
PMID:20107083
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Trpc6
transient receptor potential cation channel, subfamily C, member 6
decreases activity
ISO
Lanthanum results in decreased activity of TRPC6 protein
CTD
PMID:11179201
NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
G
Trpm6
transient receptor potential cation channel, subfamily M, member 6
multiple interactions
ISO
Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]
CTD
PMID:11988098
NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
G
Trpv6
transient receptor potential cation channel, subfamily V, member 6
multiple interactions increases uptake
ISO
Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium] TRPV6 protein results in increased uptake of Lanthanum
CTD
PMID:21146870
NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
G
Xbp1
X-box binding protein 1
increases expression
ISO
Lanthanum results in increased expression of XBP1 mRNA alternative form
CTD
PMID:18773883
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Alb
albumin
increases expression
ISO
lanthanum chloride results in increased expression of ALB mRNA
CTD
PMID:28954213
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Alox12
arachidonate 12-lipoxygenase, 12S type
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of ALOX12 mRNA
CTD
PMID:28954213
NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
G
Aox1
aldehyde oxidase 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of AOX1 mRNA
CTD
PMID:28954213
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
G
Apoe
apolipoprotein E
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of APOE mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of APOE mRNA
CTD
PMID:28954213
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Atg12
autophagy related 12
increases expression
EXP
lanthanum chloride results in increased expression of ATG12 protein
CTD
PMID:35090998
NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
G
Atg7
autophagy related 7
increases expression
EXP
lanthanum chloride results in increased expression of ATG7 protein
CTD
PMID:35090998
NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
G
B2m
beta-2 microglobulin
increases expression
ISO
lanthanum chloride results in increased expression of B2M mRNA
CTD
PMID:28954213
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
G
Bcap31
B-cell receptor-associated protein 31
decreases expression
EXP
lanthanum chloride results in decreased expression of BCAP31 protein
CTD
PMID:35090998
NCBI chr X:151,397,567...151,429,666
Ensembl chr X:151,397,576...151,428,506
G
Becn1
beclin 1
increases expression
EXP
lanthanum chloride results in increased expression of BECN1 protein
CTD
PMID:35090998
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
G
Camk4
calcium/calmodulin-dependent protein kinase IV
decreases phosphorylation
EXP
lanthanum chloride results in decreased phosphorylation of CAMK4 protein
CTD
PMID:19643171
NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
G
Casp3
caspase 3
increases expression
EXP
lanthanum chloride results in increased expression of CASP3 protein
CTD
PMID:21793157
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Casp9
caspase 9
increases expression
EXP
lanthanum chloride results in increased expression of CASP9 protein
CTD
PMID:21793157
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cat
catalase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of CAT mRNA
CTD
PMID:28954213
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Ccl5
C-C motif chemokine ligand 5
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of CCL5 mRNA lanthanum chloride results in increased expression of CCL5 mRNA
CTD
PMID:28954213
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
G
Ccs
copper chaperone for superoxide dismutase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] affects the expression of CCS mRNA
CTD
PMID:28954213
NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915
G
Cygb
cytoglobin
multiple interactions affects expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of CYGB mRNA lanthanum chloride affects the expression of CYGB mRNA
CTD
PMID:28954213
NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
G
Duox1
dual oxidase 1
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX1 mRNA lanthanum chloride results in increased expression of DUOX1 mRNA
CTD
PMID:28954213
NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
G
Duox2
dual oxidase 2
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX2 mRNA
CTD
PMID:28954213
NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
G
Dusp1
dual specificity phosphatase 1
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of DUSP1 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of DUSP1 mRNA
CTD
PMID:28954213
NCBI chr10:16,680,478...16,683,275
G
Egr1
early growth response 1
decreases expression
EXP
lanthanum chloride results in decreased expression of EGR1 mRNA; lanthanum chloride results in decreased expression of EGR1 protein
CTD
PMID:19643171 PMID:21624330
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Ephx2
epoxide hydrolase 2
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of EPHX2 mRNA
CTD
PMID:28954213
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
G
Epx
eosinophil peroxidase
increases expression
ISO
lanthanum chloride results in increased expression of EPX mRNA
CTD
PMID:28954213
NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
G
Fis1
fission, mitochondrial 1
decreases expression
EXP
lanthanum chloride results in decreased expression of FIS1 protein
CTD
PMID:35090998
NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
lanthanum chloride results in decreased expression of FOS protein
CTD
PMID:19643171
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Foxm1
forkhead box M1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of FOXM1 mRNA
CTD
PMID:28954213
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA
CTD
PMID:28954213
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression multiple interactions decreases expression
ISO
lanthanum chloride results in increased expression of GCLC mRNA; lanthanum chloride results in increased expression of GCLC protein [cerous chloride co-treated with lanthanum chloride] results in increased expression of GCLC mRNA lanthanum chloride results in decreased expression of GCLC protein
CTD
PMID:24142884 PMID:28954213 PMID:33098623
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gls
glutaminase
decreases expression
EXP
lanthanum chloride results in decreased expression of GLS
CTD
PMID:29353069
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
G
Glul
glutamate-ammonia ligase
decreases expression
EXP
lanthanum chloride results in decreased expression of GLUL
CTD
PMID:29353069
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gpx3
glutathione peroxidase 3
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of GPX3 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of GPX3 mRNA
CTD
PMID:28954213
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Gpx7
glutathione peroxidase 7
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GPX7 mRNA lanthanum chloride results in decreased expression of GPX7 mRNA
CTD
PMID:28954213
NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
G
Grin1
glutamate ionotropic receptor NMDA type subunit 1
increases expression
EXP
lanthanum chloride results in increased expression of GRIN1
CTD
PMID:29353069
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
increases expression
EXP
lanthanum chloride results in increased expression of GRIN2A
CTD
PMID:29353069
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
increases expression
EXP
lanthanum chloride results in increased expression of GRIN2B
CTD
PMID:29353069
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Gstz1
glutathione S-transferase zeta 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GSTZ1 mRNA
CTD
PMID:28954213
NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
G
Hmox1
heme oxygenase 1
multiple interactions decreases expression increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of HMOX1 mRNA lanthanum chloride results in decreased expression of HMOX1 protein lanthanum chloride results in increased expression of HMOX1 mRNA; lanthanum chloride results in increased expression of HMOX1 protein lanthanum chloride results in decreased expression of HMOX1 mRNA
CTD
PMID:24142884 PMID:28954213 PMID:33098623
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
lanthanum chloride results in decreased expression of JUN mRNA; lanthanum chloride results in decreased expression of JUN protein
CTD
PMID:21624330
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kcnip1
potassium voltage-gated channel interacting protein 1
decreases expression
EXP
lanthanum chloride results in decreased expression of KCNIP1 protein
CTD
PMID:35090998
NCBI chr10:18,219,519...18,588,833
Ensembl chr10:18,219,519...18,589,045
G
Keap1
Kelch-like ECH-associated protein 1
increases expression
ISO
lanthanum chloride results in increased expression of KEAP1 protein
CTD
PMID:33098623
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Lamp2
lysosomal-associated membrane protein 2
increases expression
EXP
lanthanum chloride results in increased expression of LAMP2 protein
CTD
PMID:35090998
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Ldha
lactate dehydrogenase A
decreases expression
EXP
lanthanum chloride results in decreased expression of LDHA mRNA; lanthanum chloride results in decreased expression of LDHA protein
CTD
PMID:29264619
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
G
Ldhb
lactate dehydrogenase B
increases expression
EXP
lanthanum chloride results in increased expression of LDHB mRNA; lanthanum chloride results in increased expression of LDHB protein
CTD
PMID:29264619
NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
G
Lpo
lactoperoxidase
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of LPO mRNA lanthanum chloride results in increased expression of LPO mRNA
CTD
PMID:28954213
NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
EXP ISO
lanthanum chloride results in increased expression of MAP1LC3B protein modified form
CTD
PMID:35090998 PMID:38253231
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
G
Mb
myoglobin
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MB mRNA lanthanum chloride results in increased expression of MB mRNA
CTD
PMID:28954213
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
G
Mbl2
mannose binding lectin 2
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of MBL2 mRNA lanthanum chloride results in decreased expression of MBL2 mRNA
CTD
PMID:28954213
NCBI chr 1:228,016,439...228,024,736
G
Mfn1
mitofusin 1
decreases expression
EXP
lanthanum chloride results in decreased expression of MFN1 protein
CTD
PMID:35090998
NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
G
Mfn2
mitofusin 2
decreases expression
EXP
lanthanum chloride results in decreased expression of MFN2 protein
CTD
PMID:35090998
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
G
Mpo
myeloperoxidase
affects expression
ISO
lanthanum chloride affects the expression of MPO mRNA
CTD
PMID:28954213
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
G
Mpv17
mitochondrial inner membrane protein MPV17
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MPV17 mRNA
CTD
PMID:28954213
NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244
G
Mtor
mechanistic target of rapamycin kinase
decreases expression
EXP
lanthanum chloride results in decreased expression of MTOR protein modified form
CTD
PMID:35090998
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Ncf1
neutrophil cytosolic factor 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF1 mRNA
CTD
PMID:28954213
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
G
Ncf2
neutrophil cytosolic factor 2
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF2 mRNA
CTD
PMID:28954213
NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
ISO
lanthanum chloride results in increased expression of NFE2L2 mRNA; lanthanum chloride results in increased expression of NFE2L2 protein
CTD
PMID:24142884 PMID:33098623
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nos2
nitric oxide synthase 2
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of NOS2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of NOS2 mRNA
CTD
PMID:28954213
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nox4
NADPH oxidase 4
increases expression
EXP
lanthanum chloride results in increased expression of NOX4 protein
CTD
PMID:35090998
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
G
Npm1
nucleophosmin 1
multiple interactions
ISO
lanthanum chloride results in decreased expression of and affects the localization of NPM1 protein
CTD
PMID:38253231
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 Ensembl chr X:17,739,941...17,751,645
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Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression
ISO
lanthanum chloride results in decreased expression of NQO1 protein
CTD
PMID:33098623
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nudt1
nudix hydrolase 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of NUDT1 mRNA
CTD
PMID:28954213
NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826
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Pcna
proliferating cell nuclear antigen
affects expression multiple interactions
ISO
lanthanum chloride affects the expression of PCNA protein [cerous chloride co-treated with lanthanum chloride] affects the expression of PCNA protein
CTD
PMID:28954213
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Prdx1
peroxiredoxin 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PRDX1 mRNA
CTD
PMID:28954213
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prdx5
peroxiredoxin 5
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of PRDX5 mRNA
CTD
PMID:28954213
NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
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Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PREX1 mRNA lanthanum chloride results in decreased expression of PREX1 mRNA
CTD
PMID:28954213
NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688
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Pxdn
peroxidasin
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PXDN mRNA lanthanum chloride results in decreased expression of PXDN mRNA
CTD
PMID:28954213
NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345
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Pygb
glycogen phosphorylase B
decreases expression
EXP
lanthanum chloride results in decreased expression of PYGB mRNA; lanthanum chloride results in decreased expression of PYGB protein
CTD
PMID:29264619
NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
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Rab7a
RAB7A, member RAS oncogene family
increases expression
EXP
lanthanum chloride results in increased expression of RAB7A protein
CTD
PMID:35090998
NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
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Rad51
RAD51 recombinase
multiple interactions
ISO
[lanthanum chloride co-treated with Cisplatin] results in increased expression of RAD51 protein
CTD
PMID:38253231
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
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Rmdn3
regulator of microtubule dynamics 3
decreases expression
EXP
lanthanum chloride results in decreased expression of RMDN3 protein
CTD
PMID:35090998
NCBI chr 3:106,125,961...106,146,568
Ensembl chr 3:106,125,951...106,146,586
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Scara3
scavenger receptor class A, member 3
increases expression
ISO
lanthanum chloride results in increased expression of SCARA3 mRNA
CTD
PMID:28954213
NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894
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Selenop
selenoprotein P
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SELENOP mRNA lanthanum chloride results in increased expression of SELENOP mRNA
CTD
PMID:28954213
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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Sirt2
sirtuin 2
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SIRT2 mRNA lanthanum chloride results in increased expression of SIRT2 mRNA
CTD
PMID:28954213
NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
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Slc16a1
solute carrier family 16 member 1
decreases expression
EXP
lanthanum chloride results in decreased expression of SLC16A1 mRNA; lanthanum chloride results in decreased expression of SLC16A1 protein
CTD
PMID:29264619
NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
G
Slc16a3
solute carrier family 16 member 3
decreases expression
EXP
lanthanum chloride results in decreased expression of SLC16A3 mRNA; lanthanum chloride results in decreased expression of SLC16A3 protein
CTD
PMID:29264619
NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
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Slc16a7
solute carrier family 16 member 7
decreases expression
EXP
lanthanum chloride results in decreased expression of SLC16A7 mRNA; lanthanum chloride results in decreased expression of SLC16A7 protein
CTD
PMID:29264619
NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
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Slc1a2
solute carrier family 1 member 2
decreases expression
EXP
lanthanum chloride results in decreased expression of SLC1A2
CTD
PMID:29353069
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
G
Slc1a3
solute carrier family 1 member 3
decreases expression
EXP
lanthanum chloride results in decreased expression of SLC1A3
CTD
PMID:29353069
NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
G
Slc2a1
solute carrier family 2 member 1
decreases expression
EXP
lanthanum chloride results in decreased expression of SLC2A1 mRNA; lanthanum chloride results in decreased expression of SLC2A1 protein
CTD
PMID:29264619
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
G
Sod2
superoxide dismutase 2
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SOD2 mRNA lanthanum chloride results in increased expression of SOD2 mRNA
CTD
PMID:28954213
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sqstm1
sequestosome 1
multiple interactions decreases expression
ISO EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA lanthanum chloride results in decreased expression of SQSTM1 protein
CTD
PMID:28954213 PMID:35090998
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
G
Srxn1
sulfiredoxin 1
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of SRXN1 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of SRXN1 mRNA
CTD
PMID:28954213
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Stk25
serine/threonine kinase 25
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of STK25 mRNA
CTD
PMID:28954213
NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244
G
Stx17
syntaxin 17
increases expression
EXP
lanthanum chloride results in increased expression of STX17 protein
CTD
PMID:35090998
NCBI chr 5:62,446,138...62,506,108
Ensembl chr 5:62,446,187...62,504,451
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Ucp2
uncoupling protein 2
decreases expression multiple interactions
ISO
lanthanum chloride results in decreased expression of UCP2 mRNA [cerous chloride co-treated with lanthanum chloride] affects the expression of UCP2 mRNA
CTD
PMID:28954213
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
G
Ulk1
unc-51 like autophagy activating kinase 1
increases expression decreases expression
EXP
lanthanum chloride results in increased expression of ULK1 protein lanthanum chloride results in decreased expression of ULK1 protein modified form
CTD
PMID:35090998
NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
G
Vapb
VAMP associated protein B and C
decreases expression
EXP
lanthanum chloride results in decreased expression of VAPB protein
CTD
PMID:35090998
NCBI chr 3:162,535,974...162,578,747
Ensembl chr 3:162,535,905...162,573,763
G
Cacna1g
calcium voltage-gated channel subunit alpha1 G
multiple interactions
ISO
Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
G
Cacna1g
calcium voltage-gated channel subunit alpha1 G
multiple interactions
ISO
Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
G
Atm
ATM serine/threonine kinase
affects expression multiple interactions
EXP
yttrium chloride affects the expression of ATM protein Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein]
CTD
PMID:35088107
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atr
ATR serine/threonine kinase
affects expression
EXP
yttrium chloride affects the expression of ATR protein
CTD
PMID:35088107
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
EXP
yttrium chloride results in increased expression of BAX protein
CTD
PMID:35088107
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Casp3
caspase 3
increases cleavage
EXP
yttrium chloride results in increased cleavage of CASP3 protein
CTD
PMID:35088107
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Chek2
checkpoint kinase 2
decreases phosphorylation
EXP
yttrium chloride results in decreased phosphorylation of CHEK2 protein
CTD
PMID:35088107
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
G
H2ax
H2A.X variant histone
increases phosphorylation multiple interactions
EXP
yttrium chloride results in increased phosphorylation of H2AX protein Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein]
CTD
PMID:35088107
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
G
Hmox1
heme oxygenase 1
decreases expression
EXP
yttrium chloride results in decreased expression of HMOX1 protein
CTD
PMID:35088107
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Nfe2l2
NFE2 like bZIP transcription factor 2
affects expression multiple interactions
EXP
yttrium chloride affects the expression of NFE2L2 protein Acetylcysteine affects the reaction [yttrium chloride affects the expression of NFE2L2 protein]
CTD
PMID:35088107
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions decreases expression
EXP
Acetylcysteine inhibits the reaction [yttrium chloride results in decreased expression of PPARG protein]
CTD
PMID:35088107
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Sod1
superoxide dismutase 1
increases activity
EXP
yttrium chloride results in increased activity of SOD1 protein
CTD
PMID:35088107
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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