CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: scandium group element atom
Accession: CHEBI:33335
browse the term
Synonyms: exact_synonym: group 3 elements
related_synonym: scandium group element; scandium group elements
G
Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
multiple interactions
ISO
Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr11:94,299,217...94,365,226
Ensembl chr11:94,299,217...94,365,024
G
Camk4
calcium/calmodulin-dependent protein kinase IV
decreases phosphorylation
ISO
Lanthanum results in decreased phosphorylation of CAMK4 protein
CTD
PMID:21695898
NCBI chr18:33,067,995...33,328,820
Ensembl chr18:33,067,984...33,324,281
G
Casr
calcium-sensing receptor
multiple interactions
ISO
Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Spermine binds to and results in increased activity of CASR protein]
CTD
PMID:17041782 PMID:21562303
NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
G
Chrm1
cholinergic receptor, muscarinic 1, CNS
multiple interactions
EXP
Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
CTD
PMID:18316702
NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
G
Creb1
cAMP responsive element binding protein 1
decreases phosphorylation
ISO
Lanthanum results in decreased phosphorylation of CREB1 protein
CTD
PMID:21695898
NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
G
Drd1
dopamine receptor D1
multiple interactions
ISO
Lanthanum inhibits the reaction [SCH 23390 binds to DRD1 protein]
CTD
PMID:9109525
NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
G
Drd2
dopamine receptor D2
multiple interactions
ISO
Lanthanum inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]
CTD
PMID:9109525
NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
G
Egr1
early growth response 1
decreases expression
ISO
Lanthanum results in decreased expression of EGR1 mRNA
CTD
PMID:21695898
NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
G
Fos
FBJ osteosarcoma oncogene
decreases expression
ISO
Lanthanum results in decreased expression of FOS mRNA
CTD
PMID:21695898
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757
G
Gabrb3
GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550
G
Gabrg2
gamma-aminobutyric acid type A receptor, subunit gamma 2
multiple interactions
ISO
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr11:41,801,017...41,891,684
Ensembl chr11:41,801,030...41,891,684
G
Hspa5
heat shock protein 5
multiple interactions
ISO
Lanthanum binds to and results in increased expression of HSPA5 protein
CTD
PMID:18773883
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
G
Igf2
insulin-like growth factor 2
multiple interactions
EXP
Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]
CTD
PMID:2442157
NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
G
Ins2
insulin II
decreases response to substance
ISO
Lanthanum results in decreased susceptibility to INS protein
CTD
PMID:22031853
NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
G
Jun
jun proto-oncogene
decreases expression
ISO
Lanthanum results in decreased expression of JUN mRNA
CTD
PMID:21695898
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
G
Lep
leptin
multiple interactions
EXP
Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]
CTD
PMID:20107083
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
G
Trpc6
transient receptor potential cation channel, subfamily C, member 6
decreases activity
EXP
Lanthanum results in decreased activity of TRPC6 protein
CTD
PMID:11179201
NCBI chr 9:8,543,868...8,680,753
Ensembl chr 9:8,544,143...8,680,742
G
Trpm6
transient receptor potential cation channel, subfamily M, member 6
multiple interactions
ISO
Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]
CTD
PMID:11988098
NCBI chr19:18,707,566...18,869,885
Ensembl chr19:18,727,347...18,869,875
G
Trpv6
transient receptor potential cation channel, subfamily V, member 6
multiple interactions increases uptake
ISO
Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium] TRPV6 protein results in increased uptake of Lanthanum
CTD
PMID:21146870
NCBI chr 6:41,597,553...41,613,339
Ensembl chr 6:41,597,558...41,613,339
G
Xbp1
X-box binding protein 1
increases expression
ISO
Lanthanum results in increased expression of XBP1 mRNA alternative form
CTD
PMID:18773883
NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
G
Alb
albumin
increases expression
ISO
lanthanum chloride results in increased expression of ALB mRNA
CTD
PMID:28954213
NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
G
Alox12
arachidonate 12-lipoxygenase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of ALOX12 mRNA
CTD
PMID:28954213
NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179
G
Aox1
aldehyde oxidase 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of AOX1 mRNA
CTD
PMID:28954213
NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572
G
Apoe
apolipoprotein E
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of APOE mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of APOE mRNA
CTD
PMID:28954213
NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
G
Atg12
autophagy related 12
increases expression
ISO
lanthanum chloride results in increased expression of ATG12 protein
CTD
PMID:35090998
NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
G
Atg7
autophagy related 7
increases expression
ISO
lanthanum chloride results in increased expression of ATG7 protein
CTD
PMID:35090998
NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
G
B2m
beta-2 microglobulin
increases expression
ISO
lanthanum chloride results in increased expression of B2M mRNA
CTD
PMID:28954213
NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
G
Bcap31
B cell receptor associated protein 31
decreases expression
ISO
lanthanum chloride results in decreased expression of BCAP31 protein
CTD
PMID:35090998
NCBI chr X:72,729,784...72,761,464
Ensembl chr X:72,729,784...72,759,781
G
Becn1
beclin 1, autophagy related
increases expression
ISO
lanthanum chloride results in increased expression of BECN1 protein
CTD
PMID:35090998
NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
G
Camk4
calcium/calmodulin-dependent protein kinase IV
decreases phosphorylation
ISO
lanthanum chloride results in decreased phosphorylation of CAMK4 protein
CTD
PMID:19643171
NCBI chr18:33,067,995...33,328,820
Ensembl chr18:33,067,984...33,324,281
G
Casp3
caspase 3
increases expression
ISO
lanthanum chloride results in increased expression of CASP3 protein
CTD
PMID:21793157
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
G
Casp9
caspase 9
increases expression
ISO
lanthanum chloride results in increased expression of CASP9 protein
CTD
PMID:21793157
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
G
Cat
catalase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of CAT mRNA
CTD
PMID:28954213
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
G
Ccl5
C-C motif chemokine ligand 5
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of CCL5 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of CCL5 mRNA
CTD
PMID:28954213
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
G
Ccs
copper chaperone for superoxide dismutase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] affects the expression of CCS mRNA
CTD
PMID:28954213
NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
G
Cygb
cytoglobin
affects expression multiple interactions
ISO
lanthanum chloride affects the expression of CYGB mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of CYGB mRNA
CTD
PMID:28954213
NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139
G
Duox1
dual oxidase 1
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of DUOX1 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX1 mRNA
CTD
PMID:28954213
NCBI chr 2:122,143,525...122,178,454
Ensembl chr 2:122,146,153...122,178,453
G
Duox2
dual oxidase 2
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX2 mRNA
CTD
PMID:28954213
NCBI chr 2:122,109,727...122,129,221
Ensembl chr 2:122,109,728...122,128,930
G
Dusp1
dual specificity phosphatase 1
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUSP1 mRNA lanthanum chloride results in increased expression of DUSP1 mRNA
CTD
PMID:28954213
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
G
Egr1
early growth response 1
decreases expression
ISO
lanthanum chloride results in decreased expression of EGR1 mRNA; lanthanum chloride results in decreased expression of EGR1 protein
CTD
PMID:19643171 PMID:21624330
NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
G
Ephx2
epoxide hydrolase 2, cytoplasmic
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of EPHX2 mRNA
CTD
PMID:28954213
NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
G
Epx
eosinophil peroxidase
increases expression
ISO
lanthanum chloride results in increased expression of EPX mRNA
CTD
PMID:28954213
NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
G
Fis1
fission, mitochondrial 1
decreases expression
ISO
lanthanum chloride results in decreased expression of FIS1 protein
CTD
PMID:35090998
NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
G
Fos
FBJ osteosarcoma oncogene
decreases expression
ISO
lanthanum chloride results in decreased expression of FOS protein
CTD
PMID:19643171
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
G
Foxm1
forkhead box M1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of FOXM1 mRNA
CTD
PMID:28954213
NCBI chr 6:128,339,957...128,352,849
Ensembl chr 6:128,339,930...128,353,109
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA
CTD
PMID:28954213
NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
G
Gclc
glutamate-cysteine ligase, catalytic subunit
multiple interactions increases expression decreases expression
ISO EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GCLC mRNA lanthanum chloride results in increased expression of GCLC mRNA; lanthanum chloride results in increased expression of GCLC protein lanthanum chloride results in decreased expression of GCLC protein
CTD
PMID:24142884 PMID:28954213 PMID:33098623
NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
G
Gls
glutaminase
decreases expression
ISO
lanthanum chloride results in decreased expression of GLS
CTD
PMID:29353069
NCBI chr 1:52,202,608...52,274,168
Ensembl chr 1:52,202,607...52,272,391
G
Glul
glutamate-ammonia ligase
decreases expression
ISO
lanthanum chloride results in decreased expression of GLUL
CTD
PMID:29353069
NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
G
Gpx3
glutathione peroxidase 3
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GPX3 mRNA lanthanum chloride results in increased expression of GPX3 mRNA
CTD
PMID:28954213
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
G
Gpx7
glutathione peroxidase 7
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GPX7 mRNA lanthanum chloride results in decreased expression of GPX7 mRNA
CTD
PMID:28954213
NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158
G
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
increases expression
ISO
lanthanum chloride results in increased expression of GRIN1
CTD
PMID:29353069
NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
G
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
increases expression
ISO
lanthanum chloride results in increased expression of GRIN2A
CTD
PMID:29353069
NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
G
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
increases expression
ISO
lanthanum chloride results in increased expression of GRIN2B
CTD
PMID:29353069
NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
G
Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GSTZ1 mRNA
CTD
PMID:28954213
NCBI chr12:87,192,102...87,211,497
Ensembl chr12:87,193,939...87,211,497
G
Hmox1
heme oxygenase 1
decreases expression increases expression multiple interactions
ISO EXP
lanthanum chloride results in decreased expression of HMOX1 mRNA lanthanum chloride results in decreased expression of HMOX1 protein lanthanum chloride results in increased expression of HMOX1 mRNA; lanthanum chloride results in increased expression of HMOX1 protein [cerous chloride co-treated with lanthanum chloride] results in decreased expression of HMOX1 mRNA
CTD
PMID:24142884 PMID:28954213 PMID:33098623
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
G
Jun
jun proto-oncogene
decreases expression
ISO
lanthanum chloride results in decreased expression of JUN mRNA; lanthanum chloride results in decreased expression of JUN protein
CTD
PMID:21624330
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
G
Kcnip1
Kv channel-interacting protein 1
decreases expression
ISO
lanthanum chloride results in decreased expression of KCNIP1 protein
CTD
PMID:35090998
NCBI chr11:33,579,339...33,943,854
Ensembl chr11:33,579,339...33,943,152
G
Keap1
kelch-like ECH-associated protein 1
increases expression
EXP
lanthanum chloride results in increased expression of KEAP1 protein
CTD
PMID:33098623
NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
G
Lamp2
lysosomal-associated membrane protein 2
increases expression
ISO
lanthanum chloride results in increased expression of LAMP2 protein
CTD
PMID:35090998
NCBI chr X:37,488,524...37,545,337
Ensembl chr X:37,490,234...37,545,331
G
Ldha
lactate dehydrogenase A
decreases expression
ISO
lanthanum chloride results in decreased expression of LDHA mRNA; lanthanum chloride results in decreased expression of LDHA protein
CTD
PMID:29264619
NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
G
Ldhb
lactate dehydrogenase B
increases expression
ISO
lanthanum chloride results in increased expression of LDHB mRNA; lanthanum chloride results in increased expression of LDHB protein
CTD
PMID:29264619
NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
G
Lpo
lactoperoxidase
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of LPO mRNA lanthanum chloride results in increased expression of LPO mRNA
CTD
PMID:28954213
NCBI chr11:87,697,254...87,716,750
Ensembl chr11:87,697,254...87,719,115
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
lanthanum chloride results in increased expression of MAP1LC3B protein modified form
CTD
PMID:35090998 PMID:38253231
NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
G
Mb
myoglobin
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of MB mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of MB mRNA
CTD
PMID:28954213
NCBI chr15:76,899,687...76,934,868
Ensembl chr15:76,899,687...76,934,870
G
Mbl2
mannose-binding lectin (protein C) 2
decreases expression multiple interactions
ISO
lanthanum chloride results in decreased expression of MBL2 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of MBL2 mRNA
CTD
PMID:28954213
NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
G
Mfn1
mitofusin 1
decreases expression
ISO
lanthanum chloride results in decreased expression of MFN1 protein
CTD
PMID:35090998
NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388
G
Mfn2
mitofusin 2
decreases expression
ISO
lanthanum chloride results in decreased expression of MFN2 protein
CTD
PMID:35090998
NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
G
Mpo
myeloperoxidase
affects expression
ISO
lanthanum chloride affects the expression of MPO mRNA
CTD
PMID:28954213
NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
G
Mpv17
MpV17 mitochondrial inner membrane protein
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MPV17 mRNA
CTD
PMID:28954213
NCBI chr 5:31,298,007...31,311,595
Ensembl chr 5:31,297,998...31,311,595
G
Mtor
mechanistic target of rapamycin kinase
decreases expression
ISO
lanthanum chloride results in decreased expression of MTOR protein modified form
CTD
PMID:35090998
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
G
Ncf1
neutrophil cytosolic factor 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF1 mRNA
CTD
PMID:28954213
NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
G
Ncf2
neutrophil cytosolic factor 2
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF2 mRNA
CTD
PMID:28954213
NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
increases expression
EXP
lanthanum chloride results in increased expression of NFE2L2 mRNA; lanthanum chloride results in increased expression of NFE2L2 protein
CTD
PMID:24142884 PMID:33098623
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
G
Nos2
nitric oxide synthase 2, inducible
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NOS2 mRNA lanthanum chloride results in increased expression of NOS2 mRNA
CTD
PMID:28954213
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
G
Nox4
NADPH oxidase 4
increases expression
ISO
lanthanum chloride results in increased expression of NOX4 protein
CTD
PMID:35090998
NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
G
Npm1
nucleophosmin 1
multiple interactions
ISO
lanthanum chloride results in decreased expression of and affects the localization of NPM1 protein
CTD
PMID:38253231
NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
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Nqo1
NAD(P)H dehydrogenase, quinone 1
decreases expression
EXP
lanthanum chloride results in decreased expression of NQO1 protein
CTD
PMID:33098623
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nudt1
nudix hydrolase 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of NUDT1 mRNA
CTD
PMID:28954213
NCBI chr 5:140,307,375...140,323,892
Ensembl chr 5:140,307,411...140,323,892
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Pcna
proliferating cell nuclear antigen
affects expression multiple interactions
ISO
lanthanum chloride affects the expression of PCNA protein [cerous chloride co-treated with lanthanum chloride] affects the expression of PCNA protein
CTD
PMID:28954213
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Prdx1
peroxiredoxin 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PRDX1 mRNA
CTD
PMID:28954213
NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
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Prdx5
peroxiredoxin 5
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of PRDX5 mRNA
CTD
PMID:28954213
NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474
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Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PREX1 mRNA lanthanum chloride results in decreased expression of PREX1 mRNA
CTD
PMID:28954213
NCBI chr 2:166,408,265...166,555,752
Ensembl chr 2:166,408,262...166,555,752
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Pxdn
peroxidasin
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PXDN mRNA lanthanum chloride results in decreased expression of PXDN mRNA
CTD
PMID:28954213
NCBI chr12:29,986,641...30,067,657
Ensembl chr12:29,987,607...30,067,657
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Pygb
brain glycogen phosphorylase
decreases expression
ISO
lanthanum chloride results in decreased expression of PYGB mRNA; lanthanum chloride results in decreased expression of PYGB protein
CTD
PMID:29264619
NCBI chr 2:150,628,716...150,673,668
Ensembl chr 2:150,628,655...150,673,678
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Rab7
RAB7, member RAS oncogene family
increases expression
ISO
lanthanum chloride results in increased expression of RAB7A protein
CTD
PMID:35090998
NCBI chr 6:87,976,088...88,022,252
Ensembl chr 6:87,976,088...88,022,252
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Rad51
RAD51 recombinase
multiple interactions
ISO
[lanthanum chloride co-treated with Cisplatin] results in increased expression of RAD51 protein
CTD
PMID:38253231
NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
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Rmdn3
regulator of microtubule dynamics 3
decreases expression
ISO
lanthanum chloride results in decreased expression of RMDN3 protein
CTD
PMID:35090998
NCBI chr 2:118,967,479...118,987,515
Ensembl chr 2:118,967,482...118,987,515
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Scara3
scavenger receptor class A, member 3
increases expression
ISO
lanthanum chloride results in increased expression of SCARA3 mRNA
CTD
PMID:28954213
NCBI chr14:66,156,844...66,191,427
Ensembl chr14:66,156,843...66,191,384
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Selenop
selenoprotein P
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SELENOP mRNA lanthanum chloride results in increased expression of SELENOP mRNA
CTD
PMID:28954213
NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
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Sirt2
sirtuin 2
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of SIRT2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of SIRT2 mRNA
CTD
PMID:28954213
NCBI chr 7:28,466,192...28,488,086
Ensembl chr 7:28,466,160...28,488,086
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Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC16A1 mRNA; lanthanum chloride results in decreased expression of SLC16A1 protein
CTD
PMID:29264619
NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
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Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC16A3 mRNA; lanthanum chloride results in decreased expression of SLC16A3 protein
CTD
PMID:29264619
NCBI chr11:120,839,310...120,849,826
Ensembl chr11:120,839,306...120,851,694
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Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC16A7 mRNA; lanthanum chloride results in decreased expression of SLC16A7 protein
CTD
PMID:29264619
NCBI chr10:125,055,139...125,225,455
Ensembl chr10:125,055,139...125,225,334
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Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC1A2
CTD
PMID:29353069
NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
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Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC1A3
CTD
PMID:29353069
NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248
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Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC2A1 mRNA; lanthanum chloride results in decreased expression of SLC2A1 protein
CTD
PMID:29264619
NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
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Sod2
superoxide dismutase 2, mitochondrial
increases expression multiple interactions
ISO
lanthanum chloride results in increased expression of SOD2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of SOD2 mRNA
CTD
PMID:28954213
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Sqstm1
sequestosome 1
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA lanthanum chloride results in decreased expression of SQSTM1 protein
CTD
PMID:28954213 PMID:35090998
NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SRXN1 mRNA lanthanum chloride results in increased expression of SRXN1 mRNA
CTD
PMID:28954213
NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
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Stk25
serine/threonine kinase 25 (yeast)
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of STK25 mRNA
CTD
PMID:28954213
NCBI chr 1:93,548,473...93,581,937
Ensembl chr 1:93,547,473...93,586,381
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Stx17
syntaxin 17
increases expression
ISO
lanthanum chloride results in increased expression of STX17 protein
CTD
PMID:35090998
NCBI chr 4:48,124,912...48,186,507
Ensembl chr 4:48,124,915...48,186,507
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Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] affects the expression of UCP2 mRNA lanthanum chloride results in decreased expression of UCP2 mRNA
CTD
PMID:28954213
NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
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Ulk1
unc-51 like kinase 1
increases expression decreases expression
ISO
lanthanum chloride results in increased expression of ULK1 protein lanthanum chloride results in decreased expression of ULK1 protein modified form
CTD
PMID:35090998
NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963
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Vapb
vesicle-associated membrane protein, associated protein B and C
decreases expression
ISO
lanthanum chloride results in decreased expression of VAPB protein
CTD
PMID:35090998
NCBI chr 2:173,579,378...173,626,132
Ensembl chr 2:173,579,304...173,626,132
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Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
multiple interactions
ISO
Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr11:94,299,217...94,365,226
Ensembl chr11:94,299,217...94,365,024
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Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
multiple interactions
ISO
Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr11:94,299,217...94,365,226
Ensembl chr11:94,299,217...94,365,024
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Atm
ataxia telangiectasia mutated
multiple interactions affects expression
ISO
Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein]
CTD
PMID:35088107
NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
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Atr
ataxia telangiectasia and Rad3 related
affects expression
ISO
yttrium chloride affects the expression of ATR protein
CTD
PMID:35088107
NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834
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Bax
BCL2-associated X protein
increases expression
ISO
yttrium chloride results in increased expression of BAX protein
CTD
PMID:35088107
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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Casp3
caspase 3
increases cleavage
ISO
yttrium chloride results in increased cleavage of CASP3 protein
CTD
PMID:35088107
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Chek2
checkpoint kinase 2
decreases phosphorylation
ISO
yttrium chloride results in decreased phosphorylation of CHEK2 protein
CTD
PMID:35088107
NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
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H2ax
H2A.X variant histone
increases phosphorylation multiple interactions
ISO
yttrium chloride results in increased phosphorylation of H2AX protein Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein]
CTD
PMID:35088107
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
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Hmox1
heme oxygenase 1
decreases expression
ISO
yttrium chloride results in decreased expression of HMOX1 protein
CTD
PMID:35088107
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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Nfe2l2
nuclear factor, erythroid derived 2, like 2
multiple interactions affects expression
ISO
Acetylcysteine affects the reaction [yttrium chloride affects the expression of NFE2L2 protein]
CTD
PMID:35088107
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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Pparg
peroxisome proliferator activated receptor gamma
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [yttrium chloride results in decreased expression of PPARG protein]
CTD
PMID:35088107
NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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Sod1
superoxide dismutase 1, soluble
increases activity
ISO
yttrium chloride results in increased activity of SOD1 protein
CTD
PMID:35088107
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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