CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: scandium group element atom
Accession: CHEBI:33335
browse the term
Synonyms: exact_synonym: group 3 elements
related_synonym: scandium group element; scandium group elements
G
CACNA1G
calcium voltage-gated channel subunit alpha1 G
multiple interactions
EXP
Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
G
CAMK4
calcium/calmodulin dependent protein kinase IV
decreases phosphorylation
ISO
Lanthanum results in decreased phosphorylation of CAMK4 protein
CTD
PMID:21695898
NCBI chr 5:111,223,583...111,494,886
Ensembl chr 5:111,223,653...111,494,886
G
CASR
calcium sensing receptor
multiple interactions
EXP
Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Spermine binds to and results in increased activity of CASR protein]
CTD
PMID:17041782 PMID:21562303
NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
G
CHRM1
cholinergic receptor muscarinic 1
multiple interactions
ISO
Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
CTD
PMID:18316702
NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
G
CREB1
cAMP responsive element binding protein 1
decreases phosphorylation
ISO
Lanthanum results in decreased phosphorylation of CREB1 protein
CTD
PMID:21695898
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
G
DRD1
dopamine receptor D1
multiple interactions
ISO
Lanthanum inhibits the reaction [SCH 23390 binds to DRD1 protein]
CTD
PMID:9109525
NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
G
DRD2
dopamine receptor D2
multiple interactions
ISO
Lanthanum inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]
CTD
PMID:9109525
NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
G
EGR1
early growth response 1
decreases expression
ISO
Lanthanum results in decreased expression of EGR1 mRNA
CTD
PMID:21695898
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
G
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
ISO
Lanthanum results in decreased expression of FOS mRNA
CTD
PMID:21695898
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
G
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
multiple interactions
EXP
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr 5:161,847,191...161,899,971
Ensembl chr 5:161,847,063...161,899,981
G
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
multiple interactions
EXP
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,552...26,939,539
G
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
multiple interactions
EXP
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD
PMID:9316872
NCBI chr 5:162,067,465...162,155,539
Ensembl chr 5:162,000,057...162,162,977
G
HSPA5
heat shock protein family A (Hsp70) member 5
multiple interactions
EXP
Lanthanum binds to and results in increased expression of HSPA5 protein
CTD
PMID:18773883
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
G
IGF2
insulin like growth factor 2
multiple interactions
ISO
Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]
CTD
PMID:2442157
NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391
G
INS
insulin
decreases response to substance
EXP
Lanthanum results in decreased susceptibility to INS protein
CTD
PMID:22031853
NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
G
JUN
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression
ISO
Lanthanum results in decreased expression of JUN mRNA
CTD
PMID:21695898
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
G
LEP
leptin
multiple interactions
ISO
Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]
CTD
PMID:20107083
NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
G
TRPC6
transient receptor potential cation channel subfamily C member 6
decreases activity
ISO
Lanthanum results in decreased activity of TRPC6 protein
CTD
PMID:11179201
NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562
G
TRPM6
transient receptor potential cation channel subfamily M member 6
multiple interactions
EXP
Lanthanum inhibits the reaction [TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Calcium]]
CTD
PMID:11988098
NCBI chr 9:74,722,495...74,887,921
Ensembl chr 9:74,722,495...74,888,094
G
TRPV6
transient receptor potential cation channel subfamily V member 6
multiple interactions increases uptake
EXP
Lanthanum inhibits the reaction [TRPV6 protein results in increased uptake of Calcium] TRPV6 protein results in increased uptake of Lanthanum
CTD
PMID:21146870
NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
G
XBP1
X-box binding protein 1
increases expression
EXP
Lanthanum results in increased expression of XBP1 mRNA alternative form
CTD
PMID:18773883
NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
G
ALB
albumin
increases expression
EXP
lanthanum chloride results in increased expression of ALB mRNA
CTD
PMID:28954213
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
G
ALOX12
arachidonate 12-lipoxygenase, 12S type
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of ALOX12 mRNA
CTD
PMID:28954213
NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754
G
AOX1
aldehyde oxidase 1
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of AOX1 mRNA
CTD
PMID:28954213
NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064
G
APOE
apolipoprotein E
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of APOE mRNA lanthanum chloride results in increased expression of APOE mRNA
CTD
PMID:28954213
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
G
ATG12
autophagy related 12
increases expression
ISO
lanthanum chloride results in increased expression of ATG12 protein
CTD
PMID:35090998
NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
G
ATG7
autophagy related 7
increases expression
ISO
lanthanum chloride results in increased expression of ATG7 protein
CTD
PMID:35090998
NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
G
B2M
beta-2-microglobulin
increases expression
EXP
lanthanum chloride results in increased expression of B2M mRNA
CTD
PMID:28954213
NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
G
BCAP31
B cell receptor associated protein 31
decreases expression
ISO
lanthanum chloride results in decreased expression of BCAP31 protein
CTD
PMID:35090998
NCBI chr X:153,700,492...153,724,387
Ensembl chr X:153,700,492...153,724,565
G
BECN1
beclin 1
increases expression
ISO
lanthanum chloride results in increased expression of BECN1 protein
CTD
PMID:35090998
NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
G
CAMK4
calcium/calmodulin dependent protein kinase IV
decreases phosphorylation
ISO
lanthanum chloride results in decreased phosphorylation of CAMK4 protein
CTD
PMID:19643171
NCBI chr 5:111,223,583...111,494,886
Ensembl chr 5:111,223,653...111,494,886
G
CASP3
caspase 3
increases expression
ISO
lanthanum chloride results in increased expression of CASP3 protein
CTD
PMID:21793157
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
G
CASP9
caspase 9
increases expression
ISO
lanthanum chloride results in increased expression of CASP9 protein
CTD
PMID:21793157
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
G
CAT
catalase
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of CAT mRNA
CTD
PMID:28954213
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
G
CCL5
C-C motif chemokine ligand 5
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of CCL5 mRNA lanthanum chloride results in increased expression of CCL5 mRNA
CTD
PMID:28954213
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
G
CCS
copper chaperone for superoxide dismutase
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] affects the expression of CCS mRNA
CTD
PMID:28954213
NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
G
CYGB
cytoglobin
affects expression multiple interactions
EXP
lanthanum chloride affects the expression of CYGB mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of CYGB mRNA
CTD
PMID:28954213
NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175
G
DUOX1
dual oxidase 1
increases expression multiple interactions
EXP
lanthanum chloride results in increased expression of DUOX1 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX1 mRNA
CTD
PMID:28954213
NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576
G
DUOX2
dual oxidase 2
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX2 mRNA
CTD
PMID:28954213
NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172
G
DUSP1
dual specificity phosphatase 1
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUSP1 mRNA lanthanum chloride results in increased expression of DUSP1 mRNA
CTD
PMID:28954213
NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
G
EGR1
early growth response 1
decreases expression
ISO
lanthanum chloride results in decreased expression of EGR1 mRNA; lanthanum chloride results in decreased expression of EGR1 protein
CTD
PMID:19643171 PMID:21624330
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
G
EPHX2
epoxide hydrolase 2
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of EPHX2 mRNA
CTD
PMID:28954213
NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
G
EPX
eosinophil peroxidase
increases expression
EXP
lanthanum chloride results in increased expression of EPX mRNA
CTD
PMID:28954213
NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174
G
FIS1
fission, mitochondrial 1
decreases expression
ISO
lanthanum chloride results in decreased expression of FIS1 protein
CTD
PMID:35090998
NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
G
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
ISO
lanthanum chloride results in decreased expression of FOS protein
CTD
PMID:19643171
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
G
FOXM1
forkhead box M1
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of FOXM1 mRNA
CTD
PMID:28954213
NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174
G
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA
CTD
PMID:28954213
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
G
GCLC
glutamate-cysteine ligase catalytic subunit
multiple interactions decreases expression increases expression
EXP ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GCLC mRNA lanthanum chloride results in decreased expression of GCLC protein lanthanum chloride results in increased expression of GCLC mRNA; lanthanum chloride results in increased expression of GCLC protein
CTD
PMID:24142884 PMID:28954213 PMID:33098623
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
G
GLS
glutaminase
decreases expression
ISO
lanthanum chloride results in decreased expression of GLS
CTD
PMID:29353069
NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
G
GLUL
glutamate-ammonia ligase
decreases expression
ISO
lanthanum chloride results in decreased expression of GLUL
CTD
PMID:29353069
NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206
G
GPX3
glutathione peroxidase 3
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GPX3 mRNA lanthanum chloride results in increased expression of GPX3 mRNA
CTD
PMID:28954213
NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
G
GPX7
glutathione peroxidase 7
decreases expression multiple interactions
EXP
lanthanum chloride results in decreased expression of GPX7 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of GPX7 mRNA
CTD
PMID:28954213
NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051
G
GRIN1
glutamate ionotropic receptor NMDA type subunit 1
increases expression
ISO
lanthanum chloride results in increased expression of GRIN1
CTD
PMID:29353069
NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
G
GRIN2A
glutamate ionotropic receptor NMDA type subunit 2A
increases expression
ISO
lanthanum chloride results in increased expression of GRIN2A
CTD
PMID:29353069
NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,183,337
G
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
increases expression
ISO
lanthanum chloride results in increased expression of GRIN2B
CTD
PMID:29353069
NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
G
GSTZ1
glutathione S-transferase zeta 1
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GSTZ1 mRNA
CTD
PMID:28954213
NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597
G
HMOX1
heme oxygenase 1
decreases expression multiple interactions increases expression
ISO EXP
lanthanum chloride results in decreased expression of HMOX1 protein [cerous chloride co-treated with lanthanum chloride] results in decreased expression of HMOX1 mRNA lanthanum chloride results in increased expression of HMOX1 mRNA; lanthanum chloride results in increased expression of HMOX1 protein lanthanum chloride results in decreased expression of HMOX1 mRNA
CTD
PMID:24142884 PMID:28954213 PMID:33098623
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
JUN
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression
ISO
lanthanum chloride results in decreased expression of JUN mRNA; lanthanum chloride results in decreased expression of JUN protein
CTD
PMID:21624330
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
G
KCNIP1
potassium voltage-gated channel interacting protein 1
decreases expression
ISO
lanthanum chloride results in decreased expression of KCNIP1 protein
CTD
PMID:35090998
NCBI chr 5:170,353,487...170,736,632
Ensembl chr 5:170,353,487...170,736,632
G
KEAP1
kelch like ECH associated protein 1
increases expression
ISO
lanthanum chloride results in increased expression of KEAP1 protein
CTD
PMID:33098623
NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
G
LAMP2
lysosomal associated membrane protein 2
increases expression
ISO
lanthanum chloride results in increased expression of LAMP2 protein
CTD
PMID:35090998
NCBI chr X:120,426,148...120,469,349
Ensembl chr X:120,426,148...120,469,365
G
LDHA
lactate dehydrogenase A
decreases expression
ISO
lanthanum chloride results in decreased expression of LDHA mRNA; lanthanum chloride results in decreased expression of LDHA protein
CTD
PMID:29264619
NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
G
LDHB
lactate dehydrogenase B
increases expression
ISO
lanthanum chloride results in increased expression of LDHB mRNA; lanthanum chloride results in increased expression of LDHB protein
CTD
PMID:29264619
NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857
G
LPO
lactoperoxidase
increases expression multiple interactions
EXP
lanthanum chloride results in increased expression of LPO mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of LPO mRNA
CTD
PMID:28954213
NCBI chr17:58,238,584...58,268,518
Ensembl chr17:58,218,548...58,268,518
G
MAP1LC3B
microtubule associated protein 1 light chain 3 beta
increases expression
ISO EXP
lanthanum chloride results in increased expression of MAP1LC3B protein modified form
CTD
PMID:35090998 PMID:38253231
NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
G
MB
myoglobin
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MB mRNA lanthanum chloride results in increased expression of MB mRNA
CTD
PMID:28954213
NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
G
MBL2
mannose binding lectin 2
decreases expression multiple interactions
EXP
lanthanum chloride results in decreased expression of MBL2 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of MBL2 mRNA
CTD
PMID:28954213
NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
G
MFN1
mitofusin 1
decreases expression
ISO
lanthanum chloride results in decreased expression of MFN1 protein
CTD
PMID:35090998
NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
G
MFN2
mitofusin 2
decreases expression
ISO
lanthanum chloride results in decreased expression of MFN2 protein
CTD
PMID:35090998
NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
G
MPO
myeloperoxidase
affects expression
EXP
lanthanum chloride affects the expression of MPO mRNA
CTD
PMID:28954213
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
G
MPV17
mitochondrial inner membrane protein MPV17
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MPV17 mRNA
CTD
PMID:28954213
NCBI chr 2:27,309,492...27,323,097
Ensembl chr 2:27,309,492...27,325,680
G
MTOR
mechanistic target of rapamycin kinase
decreases expression
ISO
lanthanum chloride results in decreased expression of MTOR protein modified form
CTD
PMID:35090998
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
G
NCF1
neutrophil cytosolic factor 1
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF1 mRNA
CTD
PMID:28954213
NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
G
NCF2
neutrophil cytosolic factor 2
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF2 mRNA
CTD
PMID:28954213
NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905
G
NFE2L2
NFE2 like bZIP transcription factor 2
increases expression
ISO
lanthanum chloride results in increased expression of NFE2L2 mRNA; lanthanum chloride results in increased expression of NFE2L2 protein
CTD
PMID:24142884 PMID:33098623
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
G
NOS2
nitric oxide synthase 2
increases expression multiple interactions
EXP
lanthanum chloride results in increased expression of NOS2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of NOS2 mRNA
CTD
PMID:28954213
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
G
NOX4
NADPH oxidase 4
increases expression
ISO
lanthanum chloride results in increased expression of NOX4 protein
CTD
PMID:35090998
NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
G
NPM1
nucleophosmin 1
multiple interactions
EXP
lanthanum chloride results in decreased expression of and affects the localization of NPM1 protein
CTD
PMID:38253231
NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810
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NQO1
NAD(P)H quinone dehydrogenase 1
decreases expression
ISO
lanthanum chloride results in decreased expression of NQO1 protein
CTD
PMID:33098623
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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NUDT1
nudix hydrolase 1
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of NUDT1 mRNA
CTD
PMID:28954213
NCBI chr 7:2,242,226...2,251,145
Ensembl chr 7:2,242,226...2,251,146
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PCNA
proliferating cell nuclear antigen
multiple interactions affects expression
EXP
[cerous chloride co-treated with lanthanum chloride] affects the expression of PCNA protein lanthanum chloride affects the expression of PCNA protein
CTD
PMID:28954213
NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
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PRDX1
peroxiredoxin 1
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PRDX1 mRNA
CTD
PMID:28954213
NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
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PRDX5
peroxiredoxin 5
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of PRDX5 mRNA
CTD
PMID:28954213
NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
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PREX1
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
decreases expression multiple interactions
EXP
lanthanum chloride results in decreased expression of PREX1 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of PREX1 mRNA
CTD
PMID:28954213
NCBI chr20:48,624,252...48,888,185
Ensembl chr20:48,624,252...48,827,999
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PXDN
peroxidasin
decreases expression multiple interactions
EXP
lanthanum chloride results in decreased expression of PXDN mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of PXDN mRNA
CTD
PMID:28954213
NCBI chr 2:1,631,887...1,744,901
Ensembl chr 2:1,631,887...1,744,852
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PYGB
glycogen phosphorylase B
decreases expression
ISO
lanthanum chloride results in decreased expression of PYGB mRNA; lanthanum chloride results in decreased expression of PYGB protein
CTD
PMID:29264619
NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012
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RAB7A
RAB7A, member RAS oncogene family
increases expression
ISO
lanthanum chloride results in increased expression of RAB7A protein
CTD
PMID:35090998
NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
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RAD51
RAD51 recombinase
multiple interactions
EXP
[lanthanum chloride co-treated with Cisplatin] results in increased expression of RAD51 protein
CTD
PMID:38253231
NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
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RMDN3
regulator of microtubule dynamics 3
decreases expression
ISO
lanthanum chloride results in decreased expression of RMDN3 protein
CTD
PMID:35090998
NCBI chr15:40,735,887...40,755,254
Ensembl chr15:40,735,884...40,755,851
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SCARA3
scavenger receptor class A member 3
increases expression
EXP
lanthanum chloride results in increased expression of SCARA3 mRNA
CTD
PMID:28954213
NCBI chr 8:27,633,463...27,734,141
Ensembl chr 8:27,633,868...27,676,776
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SELENOP
selenoprotein P
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SELENOP mRNA lanthanum chloride results in increased expression of SELENOP mRNA
CTD
PMID:28954213
NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392
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SIRT2
sirtuin 2
increases expression multiple interactions
EXP
lanthanum chloride results in increased expression of SIRT2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of SIRT2 mRNA
CTD
PMID:28954213
NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862
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SLC16A1
solute carrier family 16 member 1
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC16A1 mRNA; lanthanum chloride results in decreased expression of SLC16A1 protein
CTD
PMID:29264619
NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593
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SLC16A3
solute carrier family 16 member 3
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC16A3 mRNA; lanthanum chloride results in decreased expression of SLC16A3 protein
CTD
PMID:29264619
NCBI chr17:82,217,934...82,240,086
Ensembl chr17:82,217,934...82,261,129
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SLC16A7
solute carrier family 16 member 7
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC16A7 mRNA; lanthanum chloride results in decreased expression of SLC16A7 protein
CTD
PMID:29264619
NCBI chr12:59,596,029...59,789,841
Ensembl chr12:59,596,029...59,789,855
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SLC1A2
solute carrier family 1 member 2
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC1A2
CTD
PMID:29353069
NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
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SLC1A3
solute carrier family 1 member 3
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC1A3
CTD
PMID:29353069
NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
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SLC2A1
solute carrier family 2 member 1
decreases expression
ISO
lanthanum chloride results in decreased expression of SLC2A1 mRNA; lanthanum chloride results in decreased expression of SLC2A1 protein
CTD
PMID:29264619
NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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SOD2
superoxide dismutase 2
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SOD2 mRNA lanthanum chloride results in increased expression of SOD2 mRNA
CTD
PMID:28954213
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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SQSTM1
sequestosome 1
decreases expression multiple interactions
ISO EXP
lanthanum chloride results in decreased expression of SQSTM1 protein [cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA
CTD
PMID:28954213 PMID:35090998
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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SRXN1
sulfiredoxin 1
multiple interactions increases expression
EXP
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SRXN1 mRNA lanthanum chloride results in increased expression of SRXN1 mRNA
CTD
PMID:28954213
NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
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STK25
serine/threonine kinase 25
multiple interactions
EXP
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of STK25 mRNA
CTD
PMID:28954213
NCBI chr 2:241,492,670...241,509,572
Ensembl chr 2:241,492,670...241,509,730
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STX17
syntaxin 17
increases expression
ISO
lanthanum chloride results in increased expression of STX17 protein
CTD
PMID:35090998
NCBI chr 9:99,906,654...99,974,534
Ensembl chr 9:99,906,654...99,974,534
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UCP2
uncoupling protein 2
decreases expression multiple interactions
EXP
lanthanum chloride results in decreased expression of UCP2 mRNA [cerous chloride co-treated with lanthanum chloride] affects the expression of UCP2 mRNA
CTD
PMID:28954213
NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843
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ULK1
unc-51 like autophagy activating kinase 1
increases expression decreases expression
ISO
lanthanum chloride results in increased expression of ULK1 protein lanthanum chloride results in decreased expression of ULK1 protein modified form
CTD
PMID:35090998
NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150
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VAPB
VAMP associated protein B and C
decreases expression
ISO
lanthanum chloride results in decreased expression of VAPB protein
CTD
PMID:35090998
NCBI chr20:58,389,229...58,451,101
Ensembl chr20:58,389,229...58,451,101
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CACNA1G
calcium voltage-gated channel subunit alpha1 G
multiple interactions
EXP
Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
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CACNA1G
calcium voltage-gated channel subunit alpha1 G
multiple interactions
EXP
Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
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ATM
ATM serine/threonine kinase
multiple interactions affects expression
ISO
Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein]
CTD
PMID:35088107
NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
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ATR
ATR serine/threonine kinase
affects expression
ISO
yttrium chloride affects the expression of ATR protein
CTD
PMID:35088107
NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
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BAX
BCL2 associated X, apoptosis regulator
increases expression
ISO
yttrium chloride results in increased expression of BAX protein
CTD
PMID:35088107
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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CASP3
caspase 3
increases cleavage
ISO
yttrium chloride results in increased cleavage of CASP3 protein
CTD
PMID:35088107
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CHEK2
checkpoint kinase 2
decreases phosphorylation
ISO
yttrium chloride results in decreased phosphorylation of CHEK2 protein
CTD
PMID:35088107
NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
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H2AX
H2A.X variant histone
increases phosphorylation multiple interactions
ISO
yttrium chloride results in increased phosphorylation of H2AX protein Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein]
CTD
PMID:35088107
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
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HMOX1
heme oxygenase 1
decreases expression
ISO
yttrium chloride results in decreased expression of HMOX1 protein
CTD
PMID:35088107
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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NFE2L2
NFE2 like bZIP transcription factor 2
affects expression multiple interactions
ISO
yttrium chloride affects the expression of NFE2L2 protein Acetylcysteine affects the reaction [yttrium chloride affects the expression of NFE2L2 protein]
CTD
PMID:35088107
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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PPARG
peroxisome proliferator activated receptor gamma
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [yttrium chloride results in decreased expression of PPARG protein]
CTD
PMID:35088107
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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SOD1
superoxide dismutase 1
increases activity
ISO
yttrium chloride results in increased activity of SOD1 protein
CTD
PMID:35088107
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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