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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:noble gas atom
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Accession:CHEBI:33309 term browser browse the term
Synonyms:exact_synonym: noble gases
 related_synonym: Edelgas;   Edelgase;   gas noble;   gases nobles;   gaz noble;   gaz nobles;   group 18 elements;   group VIII elements;   inert gases;   rare gases


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radon atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions		 ISO Radon results in increased expression of ACTA2 mRNA; Radon results in increased expression of ACTA2 protein
MK 2206 inhibits the reaction [Radon results in increased expression of ACTA2 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of ACTA2 protein]		 CTD PMID:32949624 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Ar androgen receptor increases mutagenesis ISO Radon results in increased mutagenesis of AR exon CTD PMID:30008631 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO Melatonin inhibits the reaction [Radon results in increased cleavage of CASP3 protein] CTD PMID:33107683 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression		 ISO MK 2206 inhibits the reaction [Radon results in decreased expression of CDH1 protein]; ridaforolimus inhibits the reaction [Radon results in decreased expression of CDH1 protein]
Radon results in decreased expression of CDH1 mRNA; Radon results in decreased expression of CDH1 protein		 CTD PMID:32949624 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 increases expression
multiple interactions		 ISO Radon results in increased expression of CDH2 protein
MK 2206 inhibits the reaction [Radon results in increased expression of CDH2 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of CDH2 protein]		 CTD PMID:32949624 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases methylation ISO Radon results in increased methylation of CDKN2A promoter CTD PMID:16902270 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 increases mutagenesis ISO Radon results in increased mutagenesis of CHD4 exon CTD PMID:30008631 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Radon results in increased expression of CTNNB1 protein CTD PMID:32949624 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 ISO Radon results in increased expression of FN1 mRNA; Radon results in increased expression of FN1 protein
MK 2206 inhibits the reaction [Radon results in increased expression of FN1 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of FN1 protein]		 CTD PMID:32949624 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO Radon results in decreased expression of GSK3B protein CTD PMID:32949624 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases response to substance ISO GSTM1 gene mutant form results in increased susceptibility to Radon CTD PMID:24852519 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases response to substance ISO GSTT1 gene mutant form results in increased susceptibility to Radon CTD PMID:24852519 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Radon results in increased expression of HIF1A protein CTD PMID:32198912 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO Radon results in increased expression of HK2 protein CTD PMID:32198912 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Il6 interleukin 6 affects response to substance ISO IL6 promoter SNP affects the susceptibility to Radon CTD PMID:26372664 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions		 ISO Radon results in increased expression of MAP1LC3B protein
Melatonin inhibits the reaction [Radon results in increased expression of MAP1LC3B protein]		 CTD PMID:33107683 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation ISO Radon results in increased methylation of MGMT promoter CTD PMID:16902270 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mir1249 microRNA 1249 decreases expression ISO Radon results in decreased expression of MIR1249 mRNA CTD PMID:23294299 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712 		JBrowse link
G Mir18a microRNA 18a affects expression ISO Radon affects the expression of MIR18A mRNA CTD PMID:23294299 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir190 microRNA 190 increases expression ISO Radon results in increased expression of MIR190A mRNA CTD PMID:23294299 NCBI chr 8:67,850,987...67,851,071
Ensembl chr 8:67,850,987...67,851,071 		JBrowse link
G Mir208a microRNA 208a decreases expression ISO Radon results in decreased expression of MIR208A mRNA CTD PMID:23294299 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir375 microRNA 375 affects expression ISO Radon affects the expression of MIR375 mRNA CTD PMID:23294299 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir489 microRNA 489 decreases expression ISO Radon results in decreased expression of MIR489 mRNA CTD PMID:23294299 NCBI chr 4:31,693,355...31,693,460
Ensembl chr 4:31,693,355...31,693,460 		JBrowse link
G Mir494 microRNA 494 affects expression ISO Radon affects the expression of MIR494 mRNA CTD PMID:23294299 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir665 microRNA 665 affects expression ISO Radon affects the expression of MIR665 mRNA CTD PMID:23294299 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir711 microRNA 711 affects expression ISO Radon affects the expression of MIR711 mRNA CTD PMID:23294299 NCBI chr 8:109,621,975...109,622,042
Ensembl chr 8:109,621,975...109,622,042 		JBrowse link
G Mir874 microRNA 874 decreases expression ISO Radon results in decreased expression of MIR874 mRNA CTD PMID:23294299 NCBI chr17:6,620,649...6,620,724
Ensembl chr17:6,620,649...6,620,724 		JBrowse link
G Mir98 microRNA 98 increases expression ISO Radon results in increased expression of MIR98 mRNA CTD PMID:23294299 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression ISO Radon results in increased expression of MIRLET7C mRNA CTD PMID:23294299 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO Radon results in increased expression of MMP2 protein CTD PMID:32949624 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression
multiple interactions		 ISO Radon results in increased expression of MTOR protein modified form
MK 2206 inhibits the reaction [Radon results in increased expression of MTOR protein modified form]; ridaforolimus inhibits the reaction [Radon results in increased expression of MTOR protein modified form]		 CTD PMID:32949624 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO Radon results in increased expression of NFE2L2 protein CTD PMID:33107683 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Radon results in increased expression of NQO1 protein CTD PMID:33107683 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO Melatonin inhibits the reaction [Radon results in decreased expression of PTGS2 mRNA] CTD PMID:33107683 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A decreases expression ISO Radon results in decreased expression of SDHA protein CTD PMID:32198912 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression		 ISO MK 2206 inhibits the reaction [Radon results in increased expression of SNAI1 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of SNAI1 protein] CTD PMID:32949624 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions		 ISO Radon results in increased expression of SQSTM1 protein
Melatonin inhibits the reaction [Radon results in increased expression of SQSTM1 protein]		 CTD PMID:33107683 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Radon results in increased expression of TIMP2 protein CTD PMID:32949624 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tsc2 TSC complex subunit 2 increases mutagenesis ISO Radon results in increased mutagenesis of TSC2 exon CTD PMID:30008631 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Vim vimentin increases expression
multiple interactions		 ISO Radon results in increased expression of VIM protein
MK 2206 inhibits the reaction [Radon results in increased expression of VIM protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of VIM protein]
Radon results in increased expression of VIM mRNA; Radon results in increased expression of VIM protein		 CTD PMID:32949624 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
xenon atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator increases expression EXP Xenon results in increased expression of BCL2 protein CTD PMID:16034370 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Xenon results in increased expression of BDNF protein CTD PMID:16034370 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Xenon results in increased phosphorylation of CREB1 protein CTD PMID:16034370 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein] CTD PMID:21056583 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein] CTD PMID:21056583 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO Xenon inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:21056583 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
xenon(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator increases expression EXP Xenon results in increased expression of BCL2 protein CTD PMID:16034370 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Xenon results in increased expression of BDNF protein CTD PMID:16034370 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Xenon results in increased phosphorylation of CREB1 protein CTD PMID:16034370 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein] CTD PMID:21056583 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein] CTD PMID:21056583 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO Xenon inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:21056583 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    chemical entity 19909
      atom 19909
        main group element atom 19849
          noble gas atom 46
            argon atom + 0
            helium atom + 0
            krypton atom + 0
            neon atom + 0
            noble gas molecular entity + 6
            oganesson atom + 0
            radon atom + 40
            xenon atom + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      gas molecular entity 18492
                        noble gas atom 46
                          argon atom + 0
                          helium atom + 0
                          krypton atom + 0
                          neon atom + 0
                          noble gas molecular entity + 6
                          oganesson atom + 0
                          radon atom + 40
                          xenon atom + 6
paths to the root