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G |
TPO |
thyroid peroxidase |
decreases activity |
EXP |
captax results in decreased activity of TPO protein |
CTD |
PMID:23959146 PMID:25953703 |
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NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
|
NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Dithiothreitol metabolite results in increased expression of HSPA5 protein |
CTD |
PMID:17416481 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] |
CTD |
PMID:16785314 |
|
NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
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G |
ACACA |
acetyl-CoA carboxylase alpha |
increases phosphorylation |
EXP |
Estradiol results in increased phosphorylation of ACACA protein |
CTD |
PMID:15967841 |
|
NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
multiple interactions increases secretion |
EXP |
Benzo(a)pyrene inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol]; bisphenol A promotes the reaction [ADIPOQ protein results in increased secretion of Estradiol]; Estradiol results in increased expression of and results in increased secretion of ADIPOQ protein; halowax 1051 inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol]; Hexachlorobenzene inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol] |
CTD |
PMID:28284726 |
|
NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
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G |
ADIPOR1 |
adiponectin receptor 1 |
increases expression |
EXP |
Estradiol results in increased expression of ADIPOR1 protein |
CTD |
PMID:28284726 |
|
NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686
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G |
ADIPOR2 |
adiponectin receptor 2 |
increases expression |
EXP |
Estradiol results in increased expression of ADIPOR2 protein |
CTD |
PMID:28284726 |
|
NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235
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G |
AKT1 |
AKT serine/threonine kinase 1 |
increases phosphorylation |
EXP |
Estradiol results in increased phosphorylation of AKT1 protein |
CTD |
PMID:17348974 |
|
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G |
CD40 |
CD40 molecule |
affects expression |
EXP |
Estradiol affects the expression of CD40 protein |
CTD |
PMID:15964915 |
|
NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
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G |
CD40LG |
CD40 ligand |
affects expression |
EXP |
Estradiol affects the expression of CD40LG protein |
CTD |
PMID:15964915 |
|
NCBI chr X:111,778,666...111,788,901
Ensembl chr X:111,778,493...111,789,709
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G |
ESR1 |
estrogen receptor 1 |
decreases expression affects expression |
EXP |
Estradiol results in decreased expression of ESR1 protein; Estradiol results in decreased expression of ESR1 protein alternative form Estradiol affects the expression of ESR1 protein |
CTD |
PMID:15653758 PMID:16431846 PMID:16680078 PMID:17348974 |
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NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
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G |
ESR2 |
estrogen receptor 2 |
affects expression |
EXP |
Estradiol affects the expression of ESR2 protein |
CTD |
PMID:15653758 PMID:16680078 |
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NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565
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G |
F3 |
coagulation factor III, tissue factor |
affects expression |
EXP |
Estradiol affects the expression of F3 mRNA; Estradiol affects the expression of F3 protein |
CTD |
PMID:15964915 |
|
NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666
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G |
FGF7 |
fibroblast growth factor 7 |
increases expression |
EXP |
Estradiol results in increased expression of FGF7 mRNA |
CTD |
PMID:15271478 |
|
NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions increases chemical synthesis |
EXP |
4,4'-hexafluorisopropylidene diphenol inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; [FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol; [FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol; bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol] |
CTD |
PMID:17656051 PMID:29273543 PMID:34019995 |
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NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
HOXA10 |
homeobox A10 |
increases expression multiple interactions |
EXP |
Estradiol results in increased expression of HOXA10 mRNA Estradiol promotes the reaction [Progesterone results in increased expression of HOXA10 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of HOXA10 mRNA] |
CTD |
PMID:21705055 |
|
NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257
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G |
IGF1 |
insulin like growth factor 1 |
multiple interactions increases abundance |
EXP |
[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol; deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol affects the reaction [IGF1 protein results in increased abundance of Estradiol]; Zearalenone affects the reaction [IGF1 protein results in increased abundance of Estradiol] |
CTD |
PMID:17656051 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
LEP |
leptin |
increases secretion increases expression |
EXP |
Estradiol results in increased secretion of LEP protein Estradiol results in increased expression of LEP mRNA |
CTD |
PMID:23153703 |
|
NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323
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G |
LHB |
luteinizing hormone subunit beta |
multiple interactions increases secretion |
EXP |
Biological Products inhibits the reaction [LHB protein results in increased secretion of Estradiol]; Cod Liver Oil inhibits the reaction [LHB protein results in increased secretion of Estradiol]; Industrial Waste inhibits the reaction [LHB protein results in increased secretion of Estradiol] |
CTD |
PMID:26055946 |
|
NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
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G |
MMP2 |
matrix metallopeptidase 2 |
affects secretion |
EXP |
Estradiol affects the secretion of MMP2 protein |
CTD |
PMID:15653758 |
|
NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
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G |
NOS3 |
nitric oxide synthase 3 |
multiple interactions affects expression increases phosphorylation decreases expression |
EXP |
Estradiol results in increased phosphorylation of and results in increased activity of NOS3 protein; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of NOS3 protein] Estradiol affects the expression of NOS3 mRNA Estradiol results in decreased expression of NOS3 mRNA |
CTD |
PMID:15653758 PMID:15967841 PMID:16680078 PMID:17618301 |
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NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
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G |
PDGFB |
platelet derived growth factor subunit B |
multiple interactions |
EXP |
Estradiol affects the secretion of [PDGFB protein binds to PDGFB protein] |
CTD |
PMID:15653758 |
|
Ensembl chr 5:8,986,462...9,007,435
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G |
PGR |
progesterone receptor |
increases expression |
EXP |
Estradiol results in increased expression of PGR mRNA |
CTD |
PMID:16431846 |
|
NCBI chr 9:32,035,684...32,129,776
Ensembl chr 9:32,035,684...32,129,221
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G |
PRKAA1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
EXP |
Estradiol results in increased phosphorylation of and results in increased activity of PRKAA1 protein |
CTD |
PMID:15967841 |
|
NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707
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G |
PRLR |
prolactin receptor |
increases expression |
EXP |
Estradiol results in increased expression of PRLR protein alternative form |
CTD |
PMID:18492821 |
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NCBI chr16:20,637,568...20,655,881
Ensembl chr16:20,618,875...20,810,140
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
EXP |
Estradiol results in increased expression of PTGS2 mRNA Fulvestrant inhibits the reaction [Estradiol results in increased expression of PTGS2 mRNA] |
CTD |
PMID:21705055 |
|
NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
SPP1 |
secreted phosphoprotein 1 |
decreases expression |
EXP |
Estradiol results in decreased expression of SPP1 protein |
CTD |
PMID:15713688 |
|
NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
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G |
TNFRSF11B |
TNF receptor superfamily member 11b |
increases expression |
EXP |
Estradiol results in increased expression of TNFRSF11B protein |
CTD |
PMID:15713688 |
|
NCBI chr 4:19,850,212...19,879,132
Ensembl chr 4:19,850,350...19,879,125
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G |
FGF7 |
fibroblast growth factor 7 |
affects expression |
EXP |
estradiol 3-benzoate affects the expression of FGF7 mRNA |
CTD |
PMID:15976484 |
|
NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750
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G |
FGFR2 |
fibroblast growth factor receptor 2 |
decreases expression multiple interactions |
EXP |
estradiol 3-benzoate results in decreased expression of FGFR2 mRNA alternative form [Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of FGFR2 mRNA alternative form |
CTD |
PMID:15976484 |
|
NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
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G |
AGO2 |
argonaute RISC catalytic component 2 |
decreases expression multiple interactions |
EXP |
tetrabromobisphenol A results in decreased expression of AGO2 protein [tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of AGO2 protein |
CTD |
PMID:31266599 |
|
NCBI chr 4:2,966,794...3,012,388
Ensembl chr 4:2,919,511...3,015,334
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G |
AKT1 |
AKT serine/threonine kinase 1 |
decreases expression |
EXP |
tetrabromobisphenol A results in decreased expression of AKT1 mRNA; tetrabromobisphenol A results in decreased expression of AKT1 protein |
CTD |
PMID:35665993 |
|
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G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases activity |
EXP |
tetrabromobisphenol A results in decreased activity of ATP2A2 protein |
CTD |
PMID:17784851 |
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NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,969
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G |
ATP2A3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
decreases activity |
EXP |
tetrabromobisphenol A results in decreased activity of ATP2A3 protein |
CTD |
PMID:17784851 |
|
NCBI chr12:49,980,488...50,014,006
Ensembl chr12:49,980,497...50,025,171
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP |
tetrabromobisphenol A results in increased expression of BAX mRNA; tetrabromobisphenol A results in increased expression of BAX protein Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein] |
CTD |
PMID:35665993 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression |
EXP |
tetrabromobisphenol A results in decreased expression of BCL2 mRNA; tetrabromobisphenol A results in decreased expression of BCL2 protein |
CTD |
PMID:35665993 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CASP3 |
caspase 3 |
increases expression multiple interactions |
EXP |
tetrabromobisphenol A results in increased expression of CASP3 mRNA; tetrabromobisphenol A results in increased expression of CASP3 protein Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 protein] |
CTD |
PMID:35665993 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP8 |
caspase 8 |
multiple interactions decreases expression |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 protein] tetrabromobisphenol A results in decreased expression of CASP8 mRNA; tetrabromobisphenol A results in decreased expression of CASP8 protein |
CTD |
PMID:35665993 |
|
NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G |
CASP9 |
caspase 9 |
multiple interactions increases expression |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein] tetrabromobisphenol A results in increased expression of CASP9 mRNA; tetrabromobisphenol A results in increased expression of CASP9 protein |
CTD |
PMID:35665993 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
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G |
COX7A2L |
cytochrome c oxidase subunit 7A2 like |
increases expression multiple interactions |
EXP |
tetrabromobisphenol A results in increased expression of COX7A2L mRNA Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of COX7A2L mRNA] |
CTD |
PMID:35665993 |
|
NCBI chr 3:97,951,115...97,983,309
Ensembl chr 3:97,951,114...97,983,309
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G |
DICER1 |
dicer 1, ribonuclease III |
decreases expression multiple interactions |
EXP |
tetrabromobisphenol A results in decreased expression of DICER1 mRNA; tetrabromobisphenol A results in decreased expression of DICER1 protein [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 protein |
CTD |
PMID:31266599 |
|
NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,365,802...116,411,224
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G |
DROSHA |
drosha ribonuclease III |
increases expression |
EXP |
tetrabromobisphenol A results in increased expression of DROSHA mRNA |
CTD |
PMID:31266599 |
|
NCBI chr16:17,727,695...17,847,954
Ensembl chr16:17,565,137...17,848,162
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G |
GPER1 |
G protein-coupled estrogen receptor 1 |
decreases expression multiple interactions |
EXP |
tetrabromobisphenol A results in decreased expression of GPER1 protein [tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein |
CTD |
PMID:31266599 |
|
NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980
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G |
LOC100623720 |
collagen alpha-1(VI) chain |
increases expression multiple interactions |
EXP |
tetrabromobisphenol A results in increased expression of COL6A1 protein 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [tetrabromobisphenol A results in increased expression of COL6A1 protein]; tetrabromobisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of COL6A1 protein] |
CTD |
PMID:31266599 |
|
NCBI chr13:208,295,245...208,321,789
Ensembl chr13:208,295,451...208,313,127
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions increases expression |
EXP |
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in increased expression of MAP1LC3B protein tetrabromobisphenol A results in increased expression of MAP1LC3B protein |
CTD |
PMID:31266599 |
|
NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
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G |
MLKL |
mixed lineage kinase domain like pseudokinase |
multiple interactions increases expression |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL protein] tetrabromobisphenol A results in increased expression of MLKL mRNA; tetrabromobisphenol A results in increased expression of MLKL protein |
CTD |
PMID:35665993 |
|
NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173
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G |
PIK3CG |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
decreases expression |
EXP |
tetrabromobisphenol A results in decreased expression of PIK3CG mRNA; tetrabromobisphenol A results in decreased expression of PIK3CG protein |
CTD |
PMID:35665993 |
|
NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099
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G |
PLIN1 |
perilipin 1 |
multiple interactions increases expression |
EXP |
[tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in increased expression of PLIN1 protein tetrabromobisphenol A results in increased expression of PLIN1 protein |
CTD |
PMID:31266599 |
|
NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797
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G |
PTEN |
phosphatase and tensin homolog |
multiple interactions increases expression |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein] tetrabromobisphenol A results in increased expression of PTEN mRNA; tetrabromobisphenol A results in increased expression of PTEN protein |
CTD |
PMID:35665993 |
|
NCBI chr14:99,929,590...100,021,619
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G |
RIPK1 |
receptor interacting serine/threonine kinase 1 |
increases expression multiple interactions |
EXP |
tetrabromobisphenol A results in increased expression of RIPK1 mRNA; tetrabromobisphenol A results in increased expression of RIPK1 protein Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 protein] |
CTD |
PMID:35665993 |
|
NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
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G |
RIPK3 |
receptor interacting serine/threonine kinase 3 |
multiple interactions increases expression |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein] tetrabromobisphenol A results in increased expression of RIPK3 mRNA; tetrabromobisphenol A results in increased expression of RIPK3 protein |
CTD |
PMID:35665993 |
|
NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251
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G |
XPO5 |
exportin 5 |
multiple interactions decreases expression |
EXP |
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 protein tetrabromobisphenol A results in decreased expression of XPO5 protein |
CTD |
PMID:31266599 |
|
NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,531,919...38,569,582
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G |
CYP3A29 |
cytochrome P450 family 3 subfamily A member 29 |
increases chemical synthesis multiple interactions |
EXP |
CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone Ketoconazole inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone] |
CTD |
PMID:20863320 |
|
NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of HSPA5 protein] |
CTD |
PMID:20665602 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
PLA2G1B |
phospholipase A2 group IB |
multiple interactions |
EXP |
Aspirin promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] |
CTD |
PMID:10706128 |
|
NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,520...40,322,315
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Aspirin promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] |
CTD |
PMID:10706128 |
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NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
AGT |
angiotensinogen |
multiple interactions increases secretion |
EXP |
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [AGT protein results in increased secretion of Aldosterone]; Enkephalin, D-Penicillamine (2,5)- inhibits the reaction [AGT protein results in increased secretion of Aldosterone] |
CTD |
PMID:22100847 |
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NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
increases expression |
EXP |
Aldosterone results in increased expression of ATP1A1 protein |
CTD |
PMID:28438630 |
|
NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
increases expression |
EXP |
Aldosterone results in increased expression of GCLC protein |
CTD |
PMID:24512358 |
|
NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
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G |
HMOX1 |
heme oxygenase 1 |
increases expression |
EXP |
Aldosterone results in increased expression of HMOX1 protein |
CTD |
PMID:24512358 |
|
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo(4,5-d)pyrimidine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; acetovanillone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Aldosterone results in increased expression of and results in increased activity of NFE2L2 protein; diphenyleneiodonium inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Eplerenone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Ro 32-0432 inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; tempol inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Thioctic Acid inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; W 7 inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] |
CTD |
PMID:24512358 |
|
NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G |
SOD1 |
superoxide dismutase 1 |
increases expression |
EXP |
Aldosterone results in increased expression of SOD1 protein |
CTD |
PMID:24512358 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
TXNRD1 |
thioredoxin reductase 1 |
increases expression |
EXP |
Aldosterone results in increased expression of TXNRD1 protein |
CTD |
PMID:24512358 |
|
NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,172,260...80,236,219
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G |
CYP2D6 |
cytochrome P450 family 2 subfamily D member 6 |
increases hydroxylation |
EXP |
CYP2D6 protein results in increased hydroxylation of alfacalcidol |
CTD |
PMID:11880238 |
|
NCBI chr 5:6,539,021...6,543,643
Ensembl chr 5:6,538,907...6,543,642
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G |
CCL2 |
chemokine (C-C motif) ligand 2 |
multiple interactions |
EXP |
Tretinoin promotes the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 protein] |
CTD |
PMID:21130106 |
|
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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G |
GPD1 |
glycerol-3-phosphate dehydrogenase 1 |
decreases activity |
EXP |
Tretinoin results in decreased activity of GPD1 protein |
CTD |
PMID:15583048 |
|
NCBI chr 5:16,008,179...16,021,676
Ensembl chr 5:16,007,448...16,017,825
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G |
NRL |
neural retina leucine zipper |
increases expression |
EXP |
Tretinoin results in increased expression of NRL protein |
CTD |
PMID:16854989 |
|
NCBI chr 7:75,199,048...75,211,655
Ensembl chr 7:75,206,719...75,210,529
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
4,4'-hexafluorisopropylidene diphenol inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; [FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol; bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol] |
CTD |
PMID:34019995 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
HSD17B1 |
hydroxysteroid 17-beta dehydrogenase 1 |
multiple interactions |
EXP |
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Androstenedione] results in increased activity of HSD17B1 protein |
CTD |
PMID:16151981 |
|
NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548
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G |
INS |
insulin |
multiple interactions |
EXP |
9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; [LHB protein co-treated with INS protein] results in increased abundance of Androstenedione; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione] |
CTD |
PMID:11889176 |
|
NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
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G |
LHB |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; [LHB protein co-treated with INS protein] results in increased abundance of Androstenedione; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione] |
CTD |
PMID:11889176 |
|
NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
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G |
ENPEP |
glutamyl aminopeptidase |
multiple interactions increases hydrolysis |
EXP |
1,10-phenanthroline inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; amastatin inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] |
CTD |
PMID:8141778 |
|
NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510
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G |
HMOX2 |
heme oxygenase 2 |
increases expression |
EXP |
Betamethasone results in increased expression of HMOX2 protein |
CTD |
PMID:11698254 |
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NCBI chr 3:37,829,044...37,868,163
Ensembl chr 3:37,831,439...37,868,128
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
EXP |
Betamethasone results in decreased expression of PTGS2 protein |
CTD |
PMID:11698254 |
|
NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
ADCYAP1 |
adenylate cyclase activating polypeptide 1 |
increases expression |
EXP |
bisphenol A results in increased expression of ADCYAP1 protein |
CTD |
PMID:29569701 |
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NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
EXP |
bisphenol A inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]; bisphenol A inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; bisphenol A promotes the reaction [ADIPOQ protein results in increased secretion of Estradiol]; bisphenol A results in increased expression of and results in increased secretion of ADIPOQ protein |
CTD |
PMID:28284726 |
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NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
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G |
ADIPOR1 |
adiponectin receptor 1 |
increases expression |
EXP |
bisphenol A results in increased expression of ADIPOR1 protein |
CTD |
PMID:28284726 |
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NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686
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G |
ADIPOR2 |
adiponectin receptor 2 |
increases expression |
EXP |
bisphenol A results in increased expression of ADIPOR2 protein |
CTD |
PMID:28284726 |
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NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235
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G |
AGO2 |
argonaute RISC catalytic component 2 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of AGO2 protein [bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of AGO2 protein |
CTD |
PMID:31266599 |
|
NCBI chr 4:2,966,794...3,012,388
Ensembl chr 4:2,919,511...3,015,334
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G |
ALB |
albumin |
multiple interactions decreases expression |
EXP |
Cysteine inhibits the reaction [bisphenol A results in decreased expression of ALB protein] |
CTD |
PMID:37999554 |
|
NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696
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G |
AQP3 |
aquaporin 3 |
decreases expression |
EXP |
bisphenol A results in decreased expression of AQP3 mRNA |
CTD |
PMID:32710935 |
|
NCBI chr10:33,045,374...33,050,285
Ensembl chr10:33,045,245...33,051,082
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G |
AQP4 |
aquaporin 4 |
decreases expression |
EXP |
bisphenol A results in decreased expression of AQP4 mRNA |
CTD |
PMID:32710935 |
|
NCBI chr 6:111,407,632...111,422,169
Ensembl chr 6:111,407,639...111,422,109
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G |
AQP9 |
aquaporin 9 |
affects expression |
EXP |
bisphenol A affects the expression of AQP9 mRNA |
CTD |
PMID:32710935 |
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NCBI chr 1:113,798,380...113,848,452
Ensembl chr 1:113,794,040...113,848,683
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions increases expression |
EXP |
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF4 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of ATF4 mRNA] bisphenol A results in increased expression of ATF4 mRNA; bisphenol A results in increased expression of ATF4 protein |
CTD |
PMID:37108405 PMID:38845341 |
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NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
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G |
ATF6 |
activating transcription factor 6 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of ATF6 protein Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF6 protein] |
CTD |
PMID:37108405 |
|
NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of BAX mRNA; bisphenol A results in increased expression of BAX protein Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA] |
CTD |
PMID:37108405 PMID:38845341 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression increases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of BCL2 mRNA; bisphenol A results in decreased expression of BCL2 protein bisphenol A results in increased expression of BCL2 mRNA Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein]; ursodoxicoltaurine promotes the reaction [bisphenol A results in increased expression of BCL2 mRNA] |
CTD |
PMID:28819136 PMID:37108405 PMID:38845341 |
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NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
BCL2L1 |
BCL2 like 1 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of BCL2L1 mRNA; bisphenol A results in decreased expression of BCL2L1 protein Sodium Selenite affects the reaction [bisphenol A results in decreased expression of BCL2L1 protein] |
CTD |
PMID:28819136 PMID:37108405 |
|
NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
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G |
BECN1 |
beclin 1 |
increases expression |
EXP |
bisphenol A results in increased expression of BECN1 mRNA |
CTD |
PMID:28819136 |
|
NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
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G |
CARTPT |
CART prepropeptide |
increases expression decreases expression |
EXP |
bisphenol A results in increased expression of CARTPT protein bisphenol A results in decreased expression of CARTPT protein |
CTD |
PMID:29558425 PMID:29569701 PMID:29577965 PMID:29888781 PMID:38069115 |
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NCBI chr16:48,043,558...48,045,592
Ensembl chr16:48,043,492...48,045,592
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G |
CASP3 |
caspase 3 |
multiple interactions increases expression |
EXP |
[bisphenol A co-treated with fisetin] results in increased expression of CASP3 mRNA; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of CASP3 mRNA] bisphenol A results in increased expression of CASP3 mRNA; bisphenol A results in increased expression of CASP3 protein |
CTD |
PMID:29544186 PMID:37108405 PMID:38845341 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP8 |
caspase 8 |
multiple interactions increases expression |
EXP |
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP8 mRNA] |
CTD |
PMID:37108405 |
|
NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G |
CASP9 |
caspase 9 |
multiple interactions increases expression |
EXP |
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP9 mRNA] |
CTD |
PMID:37108405 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
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G |
CAT |
catalase |
multiple interactions decreases activity decreases expression |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased activity of CAT protein] |
CTD |
PMID:29129240 PMID:37108405 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
increases expression |
EXP |
bisphenol A results in increased expression of CDKN1A protein |
CTD |
PMID:28819136 |
|
NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,354,672...32,363,761
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G |
CLDN1 |
claudin 1 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of CLDN1 mRNA; bisphenol A results in decreased expression of CLDN1 protein Cysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of CLDN1 protein] |
CTD |
PMID:37108405 PMID:37999554 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
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G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
multiple interactions decreases expression |
EXP |
[bisphenol A co-treated with fisetin] results in decreased expression of CYP11A1 mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of CYP11A1 mRNA] |
CTD |
PMID:29544186 |
|
NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
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G |
CYP19A3 |
cytochrome P450 19A3 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of CYP19A1 protein bisphenol A inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein] |
CTD |
PMID:28284726 |
|
NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
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G |
DBH |
dopamine beta-hydroxylase |
increases expression |
EXP |
bisphenol A results in increased expression of DBH protein |
CTD |
PMID:29888781 |
|
NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,175...273,225,552
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G |
DDIT3 |
DNA damage inducible transcript 3 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of DDIT3 mRNA; bisphenol A results in increased expression of DDIT3 protein Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of DDIT3 mRNA] |
CTD |
PMID:37108405 PMID:38845341 |
|
NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
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G |
DICER1 |
dicer 1, ribonuclease III |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of DICER1 mRNA; bisphenol A results in decreased expression of DICER1 protein 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in decreased expression of DICER1 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of DICER1 mRNA |
CTD |
PMID:31266599 |
|
NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,365,802...116,411,224
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions decreases expression |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA] |
CTD |
PMID:28445388 PMID:28819136 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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G |
DNMT3B |
DNA methyltransferase 3 beta |
decreases expression |
EXP |
bisphenol A results in decreased expression of DNMT3B mRNA |
CTD |
PMID:28819136 |
|
NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072
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G |
DROSHA |
drosha ribonuclease III |
multiple interactions decreases expression |
EXP |
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in decreased expression of DROSHA protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in increased expression of DROSHA mRNA; bisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of DROSHA protein] |
CTD |
PMID:31266599 |
|
NCBI chr16:17,727,695...17,847,954
Ensembl chr16:17,565,137...17,848,162
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation |
EXP |
Sodium Selenite inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:37108405 |
|
NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of ERN1 protein Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ERN1 protein] |
CTD |
PMID:37108405 |
|
NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]] |
CTD |
PMID:29544186 PMID:34019995 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
GAL |
galanin and GMAP prepropeptide |
increases expression affects expression |
EXP |
bisphenol A results in increased expression of GAL protein bisphenol A affects the expression of GAL protein |
CTD |
PMID:29558425 PMID:29569701 PMID:29577965 PMID:29888781 PMID:38069115 |
|
NCBI chr 2:4,351,113...4,357,167
Ensembl chr 2:4,351,113...4,356,647
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions increases expression |
EXP |
Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLC mRNA] |
CTD |
PMID:37999554 |
|
NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
|
|
G |
GCLM |
glutamate-cysteine ligase modifier subunit |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of GCLM mRNA Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLM mRNA] |
CTD |
PMID:37999554 |
|
NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
|
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G |
GPER1 |
G protein-coupled estrogen receptor 1 |
multiple interactions |
EXP |
[bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein |
CTD |
PMID:31266599 |
|
NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980
|
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions decreases expression |
EXP |
[bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA bisphenol A results in decreased expression of GPX1 mRNA |
CTD |
PMID:28819136 PMID:29129240 |
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NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GYS1 |
glycogen synthase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter |
CTD |
PMID:29065941 |
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NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
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G |
HMOX1 |
heme oxygenase 1 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of HMOX1 mRNA Cysteine inhibits the reaction [bisphenol A results in decreased expression of HMOX1 mRNA] |
CTD |
PMID:37999554 |
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G |
HSD3B1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions decreases expression |
EXP |
bisphenol A promotes the reaction [fisetin results in decreased expression of HSD3B1 mRNA]; fisetin promotes the reaction [bisphenol A results in decreased expression of HSD3B1 mRNA] |
CTD |
PMID:29544186 |
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NCBI chr 4:101,565,229...101,574,110
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of HSPA5 mRNA; bisphenol A results in increased expression of HSPA5 protein Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of HSPA5 mRNA] |
CTD |
PMID:37108405 PMID:38845341 |
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NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
IFNG |
interferon gamma |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of IFNG mRNA Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IFNG mRNA] |
CTD |
PMID:37108405 PMID:38154151 |
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NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
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G |
IGF1 |
insulin like growth factor 1 |
decreases expression |
EXP |
bisphenol A results in decreased expression of IGF1 mRNA |
CTD |
PMID:32710935 |
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NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
IGF1R |
insulin like growth factor 1 receptor |
decreases expression |
EXP |
bisphenol A results in decreased expression of IGF1R mRNA |
CTD |
PMID:32710935 |
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NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
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G |
IL10 |
interleukin 10 |
multiple interactions decreases expression decreases secretion |
EXP |
Glutamine inhibits the reaction [bisphenol A results in decreased secretion of IL10 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of IL10 mRNA] |
CTD |
PMID:37108405 PMID:38154151 |
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NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
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G |
IL17A |
interleukin 17A |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of IL17A mRNA Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL17A mRNA] |
CTD |
PMID:37108405 |
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NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
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G |
IL6 |
interleukin 6 |
multiple interactions increases secretion increases expression |
EXP |
Glutamine inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA]; Glutamine inhibits the reaction [bisphenol A results in increased secretion of IL6 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA] |
CTD |
PMID:37108405 PMID:38154151 |
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NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
KEAP1 |
kelch like ECH associated protein 1 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of KEAP1 mRNA Cysteine inhibits the reaction [bisphenol A results in increased expression of KEAP1 mRNA] |
CTD |
PMID:37999554 |
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NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
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G |
LDHA |
lactate dehydrogenase A |
increases expression multiple interactions decreases methylation |
EXP |
bisphenol A results in increased expression of LDHA mRNA [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter bisphenol A results in decreased methylation of LDHA promoter |
CTD |
PMID:29065941 |
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NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
LOC100623720 |
collagen alpha-1(VI) chain |
multiple interactions decreases expression |
EXP |
bisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of COL6A1 protein] bisphenol A results in decreased expression of COL6A1 protein |
CTD |
PMID:31266599 |
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NCBI chr13:208,295,245...208,321,789
Ensembl chr13:208,295,451...208,313,127
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G |
LOC110258578 |
interleukin-1 beta-like |
increases expression multiple interactions increases secretion |
EXP |
bisphenol A results in increased expression of IL1B mRNA; bisphenol A results in increased expression of IL1B protein Glutamine inhibits the reaction [bisphenol A results in increased secretion of IL1B protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL1B mRNA] |
CTD |
PMID:29558425 PMID:37108405 PMID:38154151 |
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
increases expression |
EXP |
bisphenol A results in increased expression of MAP1LC3B protein |
CTD |
PMID:31266599 |
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NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
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G |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
affects expression |
EXP |
bisphenol A affects the expression of MAP3K7 protein |
CTD |
PMID:29577965 |
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NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057
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G |
MYD88 |
MYD88 innate immune signal transduction adaptor |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of MYD88 mRNA Glutamine inhibits the reaction [bisphenol A results in increased expression of MYD88 mRNA] |
CTD |
PMID:38154151 |
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NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109
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G |
NANOG |
Nanog homeobox |
decreases expression |
EXP |
bisphenol A results in decreased expression of NANOG mRNA |
CTD |
PMID:28819136 |
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NCBI chr 5:62,931,642...62,939,086
Ensembl chr 5:62,932,382...62,939,082
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of NFKB1 mRNA Glutamine inhibits the reaction [bisphenol A results in increased expression of NFKB1 mRNA] |
CTD |
PMID:38154151 |
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NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
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G |
NOS1 |
nitric oxide synthase 1 |
increases expression |
EXP |
bisphenol A results in increased expression of NOS1 protein |
CTD |
PMID:38069115 |
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NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944
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G |
NOX1 |
NADPH oxidase 1 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of NOX1 mRNA Cysteine inhibits the reaction [bisphenol A results in decreased expression of NOX1 mRNA] |
CTD |
PMID:37999554 |
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NCBI chr X:82,540,664...82,575,811
Ensembl chr X:82,540,667...82,586,532
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G |
OCLN |
occludin |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of OCLN protein Sodium Selenite affects the reaction [bisphenol A results in decreased expression of OCLN protein] |
CTD |
PMID:37108405 |
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NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
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G |
PLIN1 |
perilipin 1 |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of PLIN1 protein [bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in increased expression of PLIN1 protein |
CTD |
PMID:31266599 |
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NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797
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G |
POU5F1 |
POU class 5 homeobox 1 |
decreases expression |
EXP |
bisphenol A results in decreased expression of POU5F1 mRNA; bisphenol A results in decreased expression of POU5F1 protein |
CTD |
PMID:28819136 |
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NCBI chr 7:23,564,654...23,570,691
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G |
PPP1R16A |
protein phosphatase 1 regulatory subunit 16A |
increases activity multiple interactions |
EXP |
bisphenol A results in increased activity of GPT protein Cysteine inhibits the reaction [bisphenol A results in increased activity of GPT protein] |
CTD |
PMID:37999554 |
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NCBI chr 4:302,621...320,048
Ensembl chr 4:297,748...320,056
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
decreases expression |
EXP |
bisphenol A results in decreased expression of PTGS1 mRNA |
CTD |
PMID:38845341 |
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NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in decreased expression of PTGS2 mRNA] |
CTD |
PMID:38845341 |
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NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
PTX3 |
pentraxin 3 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of PTX3 mRNA ursodoxicoltaurine inhibits the reaction [bisphenol A results in decreased expression of PTX3 mRNA] |
CTD |
PMID:38845341 |
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NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
increases expression multiple interactions |
EXP |
bisphenol A results in increased expression of RELA protein Glutamine inhibits the reaction [bisphenol A results in increased expression of RELA protein] |
CTD |
PMID:38154151 |
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NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
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G |
SDHA |
succinate dehydrogenase complex flavoprotein subunit A |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of SDHA mRNA Cysteine inhibits the reaction [bisphenol A results in decreased expression of SDHA mRNA] |
CTD |
PMID:37999554 |
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NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
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G |
SI |
sucrase-isomaltase |
decreases expression |
EXP |
bisphenol A results in decreased expression of SI mRNA |
CTD |
PMID:28445388 |
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NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
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G |
SLC15A1 |
solute carrier family 15 member 1 |
decreases expression decreases methylation multiple interactions |
EXP |
bisphenol A results in decreased expression of SLC15A1 mRNA bisphenol A results in decreased methylation of SLC15A1 promoter [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter] |
CTD |
PMID:28445388 |
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NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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G |
SLC18A3 |
solute carrier family 18 member A3 |
decreases expression |
EXP |
bisphenol A results in decreased expression of SLC18A3 protein |
CTD |
PMID:29558425 PMID:29577965 |
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NCBI chr14:90,113,534...90,115,813
Ensembl chr14:90,113,844...90,115,430
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA |
CTD |
PMID:28445388 |
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NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
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G |
SLC7A1 |
solute carrier family 7 member 1 |
increases expression |
EXP |
bisphenol A results in increased expression of SLC7A1 mRNA |
CTD |
PMID:32710935 |
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NCBI chr11:6,538,053...6,604,654
Ensembl chr11:6,538,045...6,604,658
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G |
SLC7A7 |
solute carrier family 7 member 7 |
decreases expression |
EXP |
bisphenol A results in decreased expression of SLC7A7 mRNA |
CTD |
PMID:32710935 |
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NCBI chr 7:76,195,774...76,235,406
Ensembl chr 7:76,198,256...76,235,402
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G |
SOD1 |
superoxide dismutase 1 |
decreases expression |
EXP |
bisphenol A results in decreased expression of SOD1 mRNA |
CTD |
PMID:29129240 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SOD2 |
superoxide dismutase 2 |
decreases expression multiple interactions |
EXP |
bisphenol A results in decreased expression of SOD2 mRNA Cysteine inhibits the reaction [bisphenol A results in decreased expression of SOD2 mRNA] |
CTD |
PMID:37999554 |
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
SOX2 |
SRY-box transcription factor 2 |
decreases expression |
EXP |
bisphenol A results in decreased expression of SOX2 mRNA |
CTD |
PMID:28819136 |
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NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435
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G |
STAR |
steroidogenic acute regulatory protein |
multiple interactions decreases expression |
EXP |
[bisphenol A co-treated with fisetin] results in decreased expression of STAR mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of STAR mRNA] |
CTD |
PMID:29544186 |
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NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462
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G |
TAC1 |
tachykinin precursor 1 |
increases expression |
EXP |
bisphenol A results in increased expression of TAC1 protein |
CTD |
PMID:29558425 PMID:29569701 PMID:29888781 PMID:38069115 |
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NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523
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G |
TFAM |
transcription factor A, mitochondrial |
decreases expression |
EXP |
bisphenol A results in decreased expression of TFAM mRNA |
CTD |
PMID:28819136 |
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NCBI chr14:92,261,713...92,279,731
Ensembl chr14:92,259,403...92,279,731
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G |
TFF3 |
trefoil factor 3 |
multiple interactions decreases expression |
EXP |
Glutamine inhibits the reaction [bisphenol A results in decreased expression of TFF3 protein] |
CTD |
PMID:38154151 |
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NCBI chr13:205,641,038...205,644,333
Ensembl chr13:205,641,038...205,644,333
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G |
TJP1 |
tight junction protein 1 |
multiple interactions decreases expression |
EXP |
Sodium Selenite affects the reaction [bisphenol A results in decreased expression of TJP1 protein] |
CTD |
PMID:37108405 |
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NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G |
TJP2 |
tight junction protein 2 |
multiple interactions decreases expression |
EXP |
Cysteine inhibits the reaction [bisphenol A results in decreased expression of TJP2 mRNA] |
CTD |
PMID:37999554 |
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NCBI chr 1:222,474,518...222,612,989
Ensembl chr 1:222,474,639...222,612,983
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G |
TLR4 |
toll like receptor 4 |
multiple interactions increases expression |
EXP |
Glutamine inhibits the reaction [bisphenol A results in increased expression of TLR4 mRNA]; Glutamine inhibits the reaction [bisphenol A results in increased expression of TLR4 protein] bisphenol A results in increased expression of TLR4 mRNA; bisphenol A results in increased expression of TLR4 protein |
CTD |
PMID:38154151 |
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NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
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G |
TNF |
tumor necrosis factor |
increases expression increases secretion multiple interactions |
EXP |
bisphenol A results in increased expression of TNF mRNA; bisphenol A results in increased expression of TNF protein bisphenol A results in increased secretion of TNF protein Glutamine inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]; Glutamine inhibits the reaction [bisphenol A results in increased secretion of TNF protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of TNF mRNA] |
CTD |
PMID:29558425 PMID:37108405 PMID:38154151 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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G |
TP53 |
tumor protein p53 |
increases expression |
EXP |
bisphenol A results in increased expression of TP53 protein |
CTD |
PMID:28819136 |
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NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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G |
VEGFA |
vascular endothelial growth factor A |
increases expression |
EXP |
bisphenol A results in increased expression of VEGFA protein |
CTD |
PMID:20172683 |
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NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
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G |
VIP |
vasoactive intestinal peptide |
decreases expression increases expression |
EXP |
bisphenol A results in decreased expression of VIP protein bisphenol A results in increased expression of VIP protein |
CTD |
PMID:29558425 PMID:29577965 |
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NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269
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G |
XPO5 |
exportin 5 |
multiple interactions decreases expression |
EXP |
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of XPO5 protein bisphenol A results in decreased expression of XPO5 mRNA; bisphenol A results in decreased expression of XPO5 protein |
CTD |
PMID:31266599 |
|
NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,531,919...38,569,582
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
4,4'-bisphenol F inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone] |
CTD |
PMID:34019995 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
MMP9 |
matrix metallopeptidase 9 |
increases expression |
EXP |
4,4'-bisphenol F results in increased expression of MMP9 mRNA |
CTD |
PMID:34019995 |
|
NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
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G |
CYP2D6 |
cytochrome P450 family 2 subfamily D member 6 |
increases hydroxylation |
EXP |
CYP2D6 protein results in increased hydroxylation of Calcifediol |
CTD |
PMID:11880238 |
|
NCBI chr 5:6,539,021...6,543,643
Ensembl chr 5:6,538,907...6,543,642
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G |
CAT |
catalase |
multiple interactions |
EXP |
CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] |
CTD |
PMID:21984542 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
EXP |
[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide; chromium mesoporphyrin inhibits the reaction [[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide]; tin protoporphyrin IX inhibits the reaction [[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide] |
CTD |
PMID:16751286 |
|
|
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G |
NFKBIA |
NFKB inhibitor alpha |
multiple interactions |
EXP |
NFKBIA protein inhibits the reaction [Carbon Monoxide results in decreased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
|
NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
NFKBIA protein inhibits the reaction [Carbon Monoxide results in decreased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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G |
XDH |
xanthine dehydrogenase |
multiple interactions |
EXP |
[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide; CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] |
CTD |
PMID:21984542 |
|
NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169
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G |
CAT |
catalase |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein |
CTD |
PMID:29129240 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
DNMT1 |
DNA methyltransferase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GYS1 |
glycogen synthase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter |
CTD |
PMID:29065941 |
|
NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
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|
G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter |
CTD |
PMID:29065941 |
|
NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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|
G |
MTHFR |
methylenetetrahydrofolate reductase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
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G |
SI |
sucrase-isomaltase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA |
CTD |
PMID:28445388 |
|
NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
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|
G |
SLC15A1 |
solute carrier family 15 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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|
G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
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|
G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
AGT |
angiotensinogen |
multiple interactions increases secretion |
EXP |
D-Ala(2),MePhe(4),Met(0)-ol-enkephalin promotes the reaction [AGT protein results in increased secretion of Hydrocortisone] |
CTD |
PMID:22100847 |
|
NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
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G |
POMC |
proopiomelanocortin |
multiple interactions increases abundance increases secretion |
EXP |
Ditiocarb promotes the reaction [Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]]; Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone] POMC protein alternative form results in increased abundance of Hydrocortisone |
CTD |
PMID:1666317 PMID:21466817 PMID:22100847 |
|
NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
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G |
FMO1 |
flavin containing dimethylaniline monoxygenase 1 |
increases metabolic processing |
EXP |
FMO1 protein results in increased metabolism of Cysteamine |
CTD |
PMID:6439199 |
|
NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076
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G |
ESR1 |
estrogen receptor 1 |
increases expression |
EXP |
daidzein results in increased expression of ESR1 mRNA |
CTD |
PMID:19617652 |
|
NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
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G |
ESR2 |
estrogen receptor 2 |
increases expression |
EXP |
daidzein results in increased expression of ESR2 mRNA; daidzein results in increased expression of ESR2 protein |
CTD |
PMID:19617652 |
|
NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565
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G |
LHB |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
daidzein inhibits the reaction [LHB protein results in increased abundance of Progesterone] |
CTD |
PMID:19617652 |
|
NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
multiple interactions |
EXP |
daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] |
CTD |
PMID:31287969 |
|
NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
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G |
ALPL |
alkaline phosphatase, biomineralization associated |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA |
CTD |
PMID:30481989 |
|
NCBI chr 6:79,589,695...79,649,646
Ensembl chr 6:79,589,045...79,649,644
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|
G |
BCL2L1 |
BCL2 like 1 |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BCL2L1 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
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|
G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
[Troglitazone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CASP3 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CEBPA |
CCAAT enhancer binding protein alpha |
increases expression multiple interactions |
EXP |
Dexamethasone results in increased expression of CEBPA mRNA [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA] |
CTD |
PMID:11225715 PMID:30481989 |
|
NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004
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G |
CTNNB1 |
catenin beta 1 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
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G |
CYP17A1 |
cytochrome P450 family 17 subfamily A member 1 |
increases expression |
EXP |
Dexamethasone results in increased expression of CYP17A1 |
CTD |
PMID:19852296 |
|
NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
increases expression |
EXP |
Dexamethasone results in increased expression of CYP1A2 mRNA |
CTD |
PMID:24176340 |
|
NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100
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G |
CYP3A29 |
cytochrome P450 family 3 subfamily A member 29 |
increases expression |
EXP |
Dexamethasone results in increased expression of CYP3A29 mRNA |
CTD |
PMID:24176340 |
|
NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
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G |
FABP4 |
fatty acid binding protein 4 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896
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G |
IGF1 |
insulin like growth factor 1 |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
IGF1R |
insulin like growth factor 1 receptor |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
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G |
IRS1 |
insulin receptor substrate 1 |
decreases expression |
EXP |
Dexamethasone results in decreased expression of IRS1 mRNA |
CTD |
PMID:19852296 |
|
NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,307,284
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
increases expression multiple interactions |
EXP |
Dexamethasone results in increased expression of PPARG 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] |
CTD |
PMID:19852296 PMID:30481989 |
|
NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
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G |
RUNX2 |
RUNX family transcription factor 2 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687
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G |
SLC2A4 |
solute carrier family 2 member 4 |
decreases expression |
EXP |
Dexamethasone results in decreased expression of SLC2A4 mRNA; Dexamethasone results in decreased expression of SLC2A4 protein |
CTD |
PMID:19852296 |
|
NCBI chr12:52,628,746...52,634,965
Ensembl chr12:52,628,450...52,634,967
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G |
SPP1 |
secreted phosphoprotein 1 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
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G |
CASP3 |
caspase 3 |
decreases cleavage |
EXP |
dihydroouabain results in decreased cleavage of CASP3 protein |
CTD |
PMID:28438630 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
INS |
insulin |
multiple interactions |
EXP |
Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]] |
CTD |
PMID:1928324 |
|
NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
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G |
HK2 |
hexokinase 2 |
decreases expression |
EXP |
Dobutamine results in decreased expression of HK2 protein |
CTD |
PMID:19944370 |
|
NCBI chr 3:68,155,656...68,231,187
Ensembl chr 3:68,153,835...68,231,615
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G |
NOS2 |
nitric oxide synthase 2 |
affects response to substance |
EXP |
NOS2 protein affects the susceptibility to Dobutamine |
CTD |
PMID:20141602 |
|
NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
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G |
PYGM |
glycogen phosphorylase, muscle associated |
decreases expression |
EXP |
Dobutamine results in decreased expression of PYGM protein |
CTD |
PMID:19944370 |
|
NCBI chr 2:7,409,330...7,421,256
Ensembl chr 2:7,409,116...7,421,254
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
increases uptake multiple interactions |
EXP |
SLCO1A2 protein results in increased uptake of estrone sulfate Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; cefquinome inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Penicillins inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate] |
CTD |
PMID:31287969 |
|
NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
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G |
CAT |
catalase |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein |
CTD |
PMID:29129240 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CBS |
cystathionine beta-synthase |
multiple interactions increases activity |
EXP |
[Ethanol co-treated with Folic Acid deficiency] results in increased activity of CBS protein Folic Acid deficiency results in increased activity of CBS protein |
CTD |
PMID:16792574 |
|
NCBI chr13:206,205,942...206,231,363
Ensembl chr13:206,205,946...206,230,248
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G |
CSF2 |
colony stimulating factor 2 |
multiple interactions |
EXP |
[Folic Acid co-treated with Glycine] results in decreased expression of CSF2 mRNA |
CTD |
PMID:14662146 |
|
NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155
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G |
CTH |
cystathionine gamma-lyase |
multiple interactions |
EXP |
[Ethanol co-treated with Folic Acid deficiency] results in increased activity of CTH protein |
CTD |
PMID:16792574 |
|
NCBI chr 6:142,454,922...142,486,352
Ensembl chr 6:142,454,914...142,486,367
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G |
DNMT1 |
DNA methyltransferase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions |
EXP |
[Ethanol co-treated with Folic Acid deficiency] results in increased activity of GCLC protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GCLC mRNA |
CTD |
PMID:16792574 |
|
NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions increases activity increases expression |
EXP |
[Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSR protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSR mRNA Folic Acid deficiency results in increased activity of GSR protein Folic Acid deficiency results in increased expression of GSR mRNA |
CTD |
PMID:16792574 |
|
NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
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G |
GSS |
glutathione synthetase |
multiple interactions |
EXP |
[Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSS protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSS mRNA |
CTD |
PMID:16792574 |
|
NCBI chr17:38,316,199...38,342,253
Ensembl chr17:38,312,720...38,342,298
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|
G |
GYS1 |
glycogen synthase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter |
CTD |
PMID:29065941 |
|
NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
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G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter |
CTD |
PMID:29065941 |
|
NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
LOC106504562 |
glutathione S-transferase alpha M14 |
increases expression multiple interactions |
EXP |
Folic Acid deficiency results in increased expression of GSTA1 mRNA [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSTA1 mRNA |
CTD |
PMID:16792574 |
|
NCBI chr 7:46,553,813...46,567,596
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|
G |
MTHFR |
methylenetetrahydrofolate reductase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA |
CTD |
PMID:28445388 |
|
NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
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|
G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
EXP |
[Folic Acid co-treated with Glycine] results in decreased expression of PTGS1 |
CTD |
PMID:14662146 |
|
NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
[Folic Acid co-treated with Glycine] results in increased expression of PTGS2 |
CTD |
PMID:14662146 |
|
NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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|
G |
SI |
sucrase-isomaltase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA |
CTD |
PMID:28445388 |
|
NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
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G |
SLC15A1 |
solute carrier family 15 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA |
CTD |
PMID:28445388 |
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NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA |
CTD |
PMID:28445388 |
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NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
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SOD1 |
superoxide dismutase 1 |
decreases activity multiple interactions |
EXP |
Folic Acid deficiency results in decreased activity of SOD1 protein [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA; [Ethanol co-treated with Folic Acid deficiency] results in decreased activity of SOD1 protein |
CTD |
PMID:16792574 PMID:29129240 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions increases activity |
EXP |
[Ethanol co-treated with Folic Acid deficiency] results in increased activity of SOD2 protein Folic Acid deficiency results in increased activity of SOD2 protein; Folic Acid results in increased activity of SOD2 protein |
CTD |
PMID:16792574 PMID:22889112 |
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
CACNA2D1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
affects binding |
EXP |
Gabapentin binds to CACNA2D1 protein |
CTD |
PMID:11687876 |
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NCBI chr 9:97,781,057...98,265,925
Ensembl chr 9:97,781,090...98,266,969
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ESR1 |
estrogen receptor 1 |
decreases expression |
EXP |
Genistein results in decreased expression of ESR1 protein |
CTD |
PMID:22443950 |
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NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [TNF protein results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
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NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
multiple interactions |
EXP |
Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] |
CTD |
PMID:31287969 |
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NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
Genistein inhibits the reaction [TNF protein results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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G |
AOC1 |
amine oxidase copper containing 1 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in increased expression of AOC1 protein] |
CTD |
PMID:36615853 |
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NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
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G |
CYP2B6B |
cytochrome P450 family 2 subfamily B member 6B |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in decreased expression of CYP2B6B mRNA |
CTD |
PMID:36615853 |
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NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334
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G |
CYP3A39 |
cytochrome P450 3A39 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in increased expression of CYP3A39 mRNA] |
CTD |
PMID:36615853 |
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G |
DNAJC7 |
DnaJ heat shock protein family (Hsp40) member C7 |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in increased expression of DNAJC7 mRNA |
CTD |
PMID:36615853 |
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NCBI chr12:20,725,937...20,756,295
Ensembl chr12:20,725,975...20,759,000
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G |
FABP2 |
fatty acid binding protein 2 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in increased activity of FABP2 protein] |
CTD |
PMID:36615853 |
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NCBI chr 8:104,464,342...104,468,059
Ensembl chr 8:104,464,342...104,470,480
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in increased expression of GCLM mRNA |
CTD |
PMID:36615853 |
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NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
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G |
GPX4 |
glutathione peroxidase 4 |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in increased expression of GPX4 mRNA |
CTD |
PMID:36615853 |
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NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
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G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA |
CTD |
PMID:36615853 |
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G |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] |
CTD |
PMID:16785314 |
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NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
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G |
IFNG |
interferon gamma |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in increased expression of IFNG mRNA] |
CTD |
PMID:36615853 |
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NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
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G |
IL10 |
interleukin 10 |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in increased expression of IL10 mRNA |
CTD |
PMID:36615853 |
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NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
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G |
LOC100739508 |
glutathione S-transferase P-like |
multiple interactions |
EXP |
GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione] |
CTD |
PMID:14573868 |
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NCBI chr 2:5,005,498...5,009,247
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G |
LOC106504562 |
glutathione S-transferase alpha M14 |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] results in increased expression of GSTA2 mRNA; Glutathione inhibits the reaction [Paraquat results in decreased expression of GSTA1 mRNA] |
CTD |
PMID:36615853 |
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NCBI chr 7:46,553,813...46,567,596
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G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in increased expression of NR1I3 mRNA] |
CTD |
PMID:36615853 |
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NCBI chr 4:89,226,314...89,231,781
Ensembl chr 4:89,226,690...89,236,431
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G |
OCLN |
occludin |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in decreased expression of OCLN protein] |
CTD |
PMID:36615853 |
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NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
[Glutathione co-treated with Paraquat] affects the expression of SOD2 mRNA |
CTD |
PMID:36615853 |
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
TJP1 |
tight junction protein 1 |
multiple interactions |
EXP |
Glutathione inhibits the reaction [Paraquat results in decreased expression of TJP1 protein] |
CTD |
PMID:36615853 |
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NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G |
AIFM1 |
apoptosis inducing factor mitochondria associated 1 |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of AIFM1 mRNA] |
CTD |
PMID:35839969 |
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NCBI chr X:106,676,596...106,708,290
Ensembl chr X:106,670,520...106,708,317
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of BAX mRNA] |
CTD |
PMID:35839969 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of and results in increased activity of CASP3 protein]; Glycine inhibits the reaction [monobutyl phthalate results in increased expression of CASP3 mRNA] |
CTD |
PMID:35839969 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CAT |
catalase |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CAT mRNA] |
CTD |
PMID:35839969 |
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NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CDC26 |
cell division cycle 26 |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CDC26 mRNA] |
CTD |
PMID:35839969 |
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NCBI chr 1:253,893,666...253,906,659
Ensembl chr 1:253,895,885...253,906,632
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G |
CSF2 |
colony stimulating factor 2 |
multiple interactions |
EXP |
[Folic Acid co-treated with Glycine] results in decreased expression of CSF2 mRNA |
CTD |
PMID:14662146 |
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NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155
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G |
MFN1 |
mitofusin 1 |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 protein] |
CTD |
PMID:35839969 |
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NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
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G |
MFN2 |
mitofusin 2 |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN2 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN2 protein] |
CTD |
PMID:35839969 |
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NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
EXP |
[Folic Acid co-treated with Glycine] results in decreased expression of PTGS1 |
CTD |
PMID:14662146 |
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NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
[Folic Acid co-treated with Glycine] results in increased expression of PTGS2 |
CTD |
PMID:14662146 |
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NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
TUBA1B |
tubulin alpha 1b |
multiple interactions |
EXP |
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of TUBA1B mRNA] |
CTD |
PMID:35839969 |
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NCBI chr 5:15,150,229...15,153,620
Ensembl chr 5:15,149,099...15,153,620
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein] |
CTD |
PMID:36584959 |
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NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of ATF6 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
[Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA |
CTD |
PMID:36584959 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of CASP3 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP9 |
caspase 9 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
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G |
CAT |
catalase |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein; Betaine inhibits the reaction [Glyphosate results in increased expression of CAT mRNA] |
CTD |
PMID:29129240 PMID:36584959 |
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NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CLDN1 |
claudin 1 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein] |
CTD |
PMID:36584959 |
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NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
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G |
DNMT1 |
DNA methyltransferase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA |
CTD |
PMID:28445388 |
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NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA |
CTD |
PMID:28445388 |
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NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 protein] |
CTD |
PMID:36584959 |
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NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
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G |
EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 protein] |
CTD |
PMID:36584959 |
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NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of ERN1 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA |
CTD |
PMID:29129240 |
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NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GPX2 |
glutathione peroxidase 2 |
multiple interactions |
EXP |
[Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA |
CTD |
PMID:36584959 |
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NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
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G |
GYS1 |
glycogen synthase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter |
CTD |
PMID:29065941 |
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NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 protein] |
CTD |
PMID:36584959 |
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NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter |
CTD |
PMID:29065941 |
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NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
MFN1 |
mitofusin 1 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
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G |
MTHFR |
methylenetetrahydrofolate reductase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA |
CTD |
PMID:28445388 |
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NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA] |
CTD |
PMID:36584959 |
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NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
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G |
PCNA |
proliferating cell nuclear antigen |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA protein] |
CTD |
PMID:36584959 |
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NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
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G |
SDHA |
succinate dehydrogenase complex flavoprotein subunit A |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA] |
CTD |
PMID:36584959 |
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NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
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G |
SI |
sucrase-isomaltase |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA |
CTD |
PMID:28445388 |
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NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
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G |
SLC15A1 |
solute carrier family 15 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA |
CTD |
PMID:28445388 |
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NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
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G |
SLC5A1 |
solute carrier family 5 member 1 |
multiple interactions |
EXP |
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA |
CTD |
PMID:28445388 |
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NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA |
CTD |
PMID:29129240 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of SOD2 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
UQCRB |
ubiquinol-cytochrome c reductase binding protein |
multiple interactions |
EXP |
[Betaine co-treated with Glyphosate] results in decreased expression of UQCRB mRNA |
CTD |
PMID:36584959 |
|
NCBI chr 4:40,403,272...40,409,080
Ensembl chr 4:40,403,109...40,409,057
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G |
XBP1 |
X-box binding protein 1 |
multiple interactions |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of XBP1 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
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G |
ATF4 |
activating transcription factor 4 |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of ATF4 mRNA; Glyphosate results in increased expression of ATF4 protein Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein] |
CTD |
PMID:36584959 |
|
NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of ATF6 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP |
[Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA Glyphosate results in increased expression of BAX mRNA |
CTD |
PMID:36584959 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
CASP3 |
caspase 3 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of CASP3 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP9 |
caspase 9 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
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G |
CAT |
catalase |
increases expression multiple interactions increases activity |
EXP |
Glyphosate results in increased expression of CAT mRNA Betaine inhibits the reaction [Glyphosate results in increased expression of CAT mRNA] Glyphosate results in increased activity of CAT protein |
CTD |
PMID:31677563 PMID:36584959 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CLDN1 |
claudin 1 |
multiple interactions decreases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein] Glyphosate results in decreased expression of CLDN1 mRNA; Glyphosate results in decreased expression of CLDN1 protein |
CTD |
PMID:31677563 PMID:36584959 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of CXCL8 mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [Glyphosate results in increased expression of CXCL8 mRNA] |
CTD |
PMID:35388968 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 protein] Glyphosate results in increased expression of EIF2AK3 mRNA; Glyphosate results in increased expression of EIF2AK3 protein |
CTD |
PMID:36584959 |
|
NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
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G |
EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 protein] Glyphosate results in increased expression of EIF2S1 mRNA; Glyphosate results in increased expression of EIF2S1 protein |
CTD |
PMID:36584959 |
|
NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of ERN1 mRNA Betaine inhibits the reaction [Glyphosate results in increased expression of ERN1 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
decreases expression |
EXP |
Glyphosate results in decreased expression of GCLM mRNA |
CTD |
PMID:31677563 PMID:35388968 |
|
NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
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G |
GPX1 |
glutathione peroxidase 1 |
decreases expression decreases activity |
EXP |
Glyphosate results in decreased expression of GPX1 mRNA Glyphosate results in decreased activity of GPX1 protein |
CTD |
PMID:31677563 PMID:35388968 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GPX2 |
glutathione peroxidase 2 |
multiple interactions |
EXP |
[Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA |
CTD |
PMID:36584959 |
|
NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
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G |
GSTO1 |
glutathione S-transferase omega 1 |
increases expression |
EXP |
Glyphosate results in increased expression of GSTO1 mRNA |
CTD |
PMID:36584959 |
|
NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613
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G |
HMOX1 |
heme oxygenase 1 |
decreases expression multiple interactions increases expression |
EXP |
Glyphosate results in decreased expression of HMOX1 mRNA Glyphosate results in increased expression of and affects the localization of HMOX1 protein Glyphosate results in increased expression of HMOX1 mRNA |
CTD |
PMID:31677563 PMID:35388968 PMID:36584959 |
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of HSP90B1 mRNA; Glyphosate results in increased expression of HSP90B1 protein Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 protein] |
CTD |
PMID:36584959 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
IL10 |
interleukin 10 |
increases expression |
EXP |
Glyphosate results in increased expression of IL10 protein |
CTD |
PMID:36584959 |
|
NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
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G |
IL6 |
interleukin 6 |
increases expression multiple interactions affects secretion |
EXP |
Glyphosate results in increased expression of IL6 mRNA; Glyphosate results in increased expression of IL6 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Glyphosate results in increased expression of IL6 mRNA] Glyphosate affects the secretion of IL6 protein |
CTD |
PMID:31677563 PMID:35388968 PMID:36584959 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
KEAP1 |
kelch like ECH associated protein 1 |
decreases expression |
EXP |
Glyphosate results in decreased expression of KEAP1 mRNA |
CTD |
PMID:35388968 |
|
NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
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G |
LOC110258578 |
interleukin-1 beta-like |
increases expression multiple interactions increases secretion |
EXP |
Glyphosate results in increased expression of IL1B mRNA; Glyphosate results in increased expression of IL1B protein pyrrolidine dithiocarbamic acid inhibits the reaction [Glyphosate results in increased expression of IL1B mRNA] Glyphosate results in increased secretion of IL1B protein |
CTD |
PMID:35388968 PMID:36584959 |
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|
G |
MFN1 |
mitofusin 1 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of NFE2L2 mRNA]; Glyphosate results in increased expression of and affects the localization of NFE2L2 protein Glyphosate results in increased expression of NFE2L2 mRNA; Glyphosate results in increased expression of NFE2L2 protein |
CTD |
PMID:31677563 PMID:35388968 PMID:36584959 |
|
NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
increases expression |
EXP |
Glyphosate results in increased expression of NFKB1 mRNA |
CTD |
PMID:31677563 PMID:35388968 |
|
NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
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G |
NFKBIA |
NFKB inhibitor alpha |
multiple interactions |
EXP |
Glyphosate results in decreased expression of and results in increased phosphorylation of NFKBIA protein |
CTD |
PMID:35388968 |
|
NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277
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G |
NOS2 |
nitric oxide synthase 2 |
increases expression |
EXP |
Glyphosate results in increased expression of NOS2 mRNA |
CTD |
PMID:35388968 |
|
NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of NQO1 mRNA Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA] |
CTD |
PMID:31677563 PMID:35388968 PMID:36584959 |
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NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
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G |
PCNA |
proliferating cell nuclear antigen |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of PCNA mRNA; Glyphosate results in increased expression of PCNA protein Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA protein] |
CTD |
PMID:36584959 |
|
NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
increases phosphorylation |
EXP |
Glyphosate results in increased phosphorylation of RELA protein |
CTD |
PMID:35388968 |
|
NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
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G |
SDHA |
succinate dehydrogenase complex flavoprotein subunit A |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
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G |
SOD1 |
superoxide dismutase 1 |
decreases activity |
EXP |
Glyphosate results in decreased activity of SOD1 protein |
CTD |
PMID:35388968 |
|
NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SOD2 |
superoxide dismutase 2 |
increases expression multiple interactions |
EXP |
Glyphosate results in increased expression of SOD2 mRNA Betaine inhibits the reaction [Glyphosate results in increased expression of SOD2 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
SQSTM1 |
sequestosome 1 |
decreases expression multiple interactions |
EXP |
Glyphosate results in decreased expression of SQSTM1 protein Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of SQSTM1 protein] |
CTD |
PMID:35388968 |
|
NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
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G |
TJP1 |
tight junction protein 1 |
decreases expression |
EXP |
Glyphosate results in decreased expression of TJP1 mRNA |
CTD |
PMID:31677563 |
|
NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G |
TNF |
tumor necrosis factor |
affects secretion increases expression |
EXP |
Glyphosate affects the secretion of TNF protein Glyphosate results in increased expression of TNF protein |
CTD |
PMID:35388968 PMID:36584959 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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G |
UQCRB |
ubiquinol-cytochrome c reductase binding protein |
multiple interactions |
EXP |
[Betaine co-treated with Glyphosate] results in decreased expression of UQCRB mRNA |
CTD |
PMID:36584959 |
|
NCBI chr 4:40,403,272...40,409,080
Ensembl chr 4:40,403,109...40,409,057
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G |
XBP1 |
X-box binding protein 1 |
multiple interactions increases expression |
EXP |
Betaine inhibits the reaction [Glyphosate results in increased expression of XBP1 mRNA] |
CTD |
PMID:36584959 |
|
NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
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G |
HRH2 |
histamine receptor H2 |
multiple interactions |
EXP |
[Histamine affects the activity of HRH2 protein] which affects the secretion of Chlorides |
CTD |
PMID:12665126 |
|
NCBI chr 2:81,883,670...81,932,464
Ensembl chr 2:81,883,673...81,932,275
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
|
NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Dithiothreitol metabolite results in increased expression of HSPA5 protein |
CTD |
PMID:17416481 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] |
CTD |
PMID:16785314 |
|
NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
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G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:37120089 |
|
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G |
ARB2A |
ARB2 cotranscriptional regulator A |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ARB2A mRNA] |
CTD |
PMID:37120089 |
|
NCBI chr 2:100,477,770...100,893,594
Ensembl chr 2:100,477,775...100,893,580
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G |
ATG5 |
autophagy related 5 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of ATG5 protein] |
CTD |
PMID:37120089 |
|
NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein] |
CTD |
PMID:35665993 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions increases expression |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Melatonin inhibits the reaction [Malathion results in decreased expression of BCL2 mRNA] Melatonin results in increased expression of BCL2 mRNA |
CTD |
PMID:31535366 PMID:37120089 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
BECN1 |
beclin 1 |
increases expression multiple interactions |
EXP |
Melatonin results in increased expression of BECN1 protein Melatonin inhibits the reaction [deoxynivalenol results in increased expression of BECN1 protein] |
CTD |
PMID:37120089 |
|
NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
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G |
CASP3 |
caspase 3 |
decreases expression multiple interactions |
EXP |
Melatonin results in decreased expression of CASP3 mRNA Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 protein] |
CTD |
PMID:31535366 PMID:35665993 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP8 |
caspase 8 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 protein] |
CTD |
PMID:35665993 |
|
NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G |
CASP9 |
caspase 9 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein] |
CTD |
PMID:35665993 |
|
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
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G |
CAT |
catalase |
multiple interactions increases activity |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Malathion results in decreased expression of CAT mRNA] Melatonin results in increased activity of CAT protein |
CTD |
PMID:31535366 PMID:37120089 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CHUK |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CHUK mRNA] |
CTD |
PMID:37120089 |
|
NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868
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|
G |
CLDN1 |
claudin 1 |
multiple interactions increases expression |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] Melatonin results in increased expression of CLDN1 protein |
CTD |
PMID:37120089 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
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G |
COX7A2L |
cytochrome c oxidase subunit 7A2 like |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of COX7A2L mRNA] |
CTD |
PMID:35665993 |
|
NCBI chr 3:97,951,115...97,983,309
Ensembl chr 3:97,951,114...97,983,309
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G |
GPX4 |
glutathione peroxidase 4 |
increases expression |
EXP |
Melatonin results in increased expression of GPX4 mRNA |
CTD |
PMID:31535366 |
|
NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
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G |
IL18 |
interleukin 18 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA] |
CTD |
PMID:37120089 |
|
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
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G |
IL6 |
interleukin 6 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein] |
CTD |
PMID:37120089 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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|
G |
KLF5 |
KLF transcription factor 5 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of KLF5 mRNA] |
CTD |
PMID:37120089 |
|
NCBI chr11:45,370,009...45,386,673
Ensembl chr11:45,369,810...45,388,314
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein] |
CTD |
PMID:37120089 |
|
|
|
G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
Melatonin affects the reaction [deoxynivalenol results in increased expression of and results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:37120089 |
|
NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
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MAP2K1 |
mitogen-activated protein kinase kinase 1 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of MAP2K1 mRNA] |
CTD |
PMID:37120089 |
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NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226
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MLKL |
mixed lineage kinase domain like pseudokinase |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL protein] |
CTD |
PMID:35665993 |
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NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173
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MTOR |
mechanistic target of rapamycin kinase |
multiple interactions decreases phosphorylation |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein] Melatonin results in decreased phosphorylation of MTOR protein |
CTD |
PMID:37120089 |
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NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
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G |
OCLN |
occludin |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] |
CTD |
PMID:37120089 |
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NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
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G |
PLIN2 |
perilipin 2 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 protein] |
CTD |
PMID:31535366 |
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NCBI chr 1:203,683,867...203,709,277
Ensembl chr 1:203,683,862...203,709,273
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions |
EXP |
Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG protein] |
CTD |
PMID:31535366 |
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NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
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PTEN |
phosphatase and tensin homolog |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein] |
CTD |
PMID:35665993 |
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NCBI chr14:99,929,590...100,021,619
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G |
RIPK1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 protein] |
CTD |
PMID:35665993 |
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NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
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G |
RIPK3 |
receptor interacting serine/threonine kinase 3 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein] |
CTD |
PMID:35665993 |
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NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251
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G |
SOD2 |
superoxide dismutase 2 |
increases expression multiple interactions |
EXP |
Melatonin results in increased expression of SOD2 mRNA Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of SOD2 mRNA] |
CTD |
PMID:31535366 PMID:37120089 |
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
TJP1 |
tight junction protein 1 |
increases expression multiple interactions |
EXP |
Melatonin results in increased expression of TJP1 protein Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein] |
CTD |
PMID:37120089 |
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NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of TNF protein] |
CTD |
PMID:37120089 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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G |
TP53 |
tumor protein p53 |
multiple interactions decreases expression |
EXP |
Melatonin inhibits the reaction [Malathion results in increased expression of TP53 mRNA] Melatonin results in decreased expression of TP53 mRNA |
CTD |
PMID:31535366 |
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NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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G |
ZFP36L2 |
ZFP36 ring finger protein like 2 |
multiple interactions |
EXP |
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ZFP36L2 mRNA] |
CTD |
PMID:37120089 |
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NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,407...97,204,698
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
Mercaptoethanol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
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NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] |
CTD |
PMID:38438008 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 mRNA] |
CTD |
PMID:38438008 |
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NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA] |
CTD |
PMID:38438008 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CLDN1 |
claudin 1 |
multiple interactions |
EXP |
[N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA] |
CTD |
PMID:37271275 PMID:38438008 |
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NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
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G |
IL6 |
interleukin 6 |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 mRNA] |
CTD |
PMID:38438008 |
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NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
LDHA |
lactate dehydrogenase A |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in increased activity of LDHA protein] |
CTD |
PMID:38438008 |
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NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions |
EXP |
[N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL1B mRNA]; theanine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
CTD |
PMID:37271275 PMID:38438008 |
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MAPK14 |
mitogen-activated protein kinase 14 |
multiple interactions |
EXP |
[SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK14 protein]; theanine inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA] |
CTD |
PMID:37271275 PMID:38438008 |
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NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,877...31,862,031
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions |
EXP |
[N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; theanine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA] |
CTD |
PMID:37271275 |
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NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228
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G |
OCLN |
occludin |
multiple interactions |
EXP |
[N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN protein]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA] |
CTD |
PMID:37271275 PMID:38438008 |
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NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
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RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RELA protein] |
CTD |
PMID:38438008 |
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NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
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G |
TJP1 |
tight junction protein 1 |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 protein] |
CTD |
PMID:38438008 |
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NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of TNF mRNA] |
CTD |
PMID:38438008 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
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G |
ACE |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
multiple interactions |
EXP |
ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] |
CTD |
PMID:12672649 |
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NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703
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AGT |
angiotensinogen |
affects activity |
EXP |
Nitric Oxide affects the activity of AGT protein |
CTD |
PMID:21127344 |
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NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions |
EXP |
Nitric Oxide results in increased phosphorylation of and results in decreased activity of BCL2 protein |
CTD |
PMID:16039061 |
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NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CAPN1 |
calpain 1 |
decreases expression |
EXP |
Nitric Oxide results in decreased expression of CAPN1 mRNA |
CTD |
PMID:9728040 |
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NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,985...7,022,684
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G |
EDN1 |
endothelin 1 |
increases abundance multiple interactions |
EXP |
EDN1 protein results in increased abundance of Nitric Oxide Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein] |
CTD |
PMID:12672649 PMID:17105827 |
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NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
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KNG1 |
kininogen 1 |
multiple interactions increases abundance |
EXP |
ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] |
CTD |
PMID:12672649 |
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NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,340...124,557,958
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G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Resveratrol inhibits the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide] |
CTD |
PMID:20825639 |
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NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
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G |
NOS3 |
nitric oxide synthase 3 |
multiple interactions decreases activity |
EXP |
TXNRD1 protein inhibits the reaction [Nitric Oxide results in decreased activity of NOS3 protein] |
CTD |
PMID:8810647 PMID:10823391 |
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NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
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G |
TAC1 |
tachykinin precursor 1 |
increases abundance |
EXP |
TAC1 protein results in increased abundance of Nitric Oxide |
CTD |
PMID:12672649 |
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NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523
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G |
TXNRD1 |
thioredoxin reductase 1 |
multiple interactions |
EXP |
TXNRD1 protein inhibits the reaction [Nitric Oxide results in decreased activity of NOS3 protein] |
CTD |
PMID:8810647 |
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NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,172,260...80,236,219
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G |
IL10 |
interleukin 10 |
decreases expression |
EXP |
notoginsenoside R1 results in decreased expression of IL10 protein |
CTD |
PMID:25721049 |
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NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
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G |
IL4 |
interleukin 4 |
decreases expression |
EXP |
notoginsenoside R1 results in decreased expression of IL4 protein |
CTD |
PMID:25721049 |
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NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases activity |
EXP |
Ouabain results in decreased activity of ATP1A1 protein |
CTD |
PMID:28438630 |
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NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680
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G |
CASP3 |
caspase 3 |
decreases cleavage |
EXP |
Ouabain results in decreased cleavage of CASP3 protein |
CTD |
PMID:28438630 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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GHRL |
ghrelin and obestatin prepropeptide |
multiple interactions increases secretion |
EXP |
STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Oxytocin] |
CTD |
PMID:19528263 |
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NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917
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G |
STAT1 |
signal transducer and activator of transcription 1 |
multiple interactions increases secretion |
EXP |
STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Oxytocin] STAT1 protein results in increased secretion of Oxytocin |
CTD |
PMID:19528263 |
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NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
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G |
ABCB4 |
ATP binding cassette subfamily B member 4 |
increases export multiple interactions |
EXP |
ABCB4 protein results in increased export of Phosphatidylcholines Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] |
CTD |
PMID:21056966 |
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NCBI chr 9:93,171,371...93,262,124
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G |
PDIA3 |
protein disulfide isomerase family A member 3 |
increases hydrolysis |
EXP |
PDIA3 protein results in increased hydrolysis of Phosphatidylcholines |
CTD |
PMID:16798117 |
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NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
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AGT |
angiotensinogen |
increases secretion |
EXP |
AGT protein results in increased secretion of Progesterone |
CTD |
PMID:22100847 |
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NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
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G |
CRABP1 |
cellular retinoic acid binding protein 1 |
affects expression |
EXP |
Progesterone affects the expression of CRABP1 protein |
CTD |
PMID:11833939 |
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NCBI chr 7:47,602,316...47,608,865
Ensembl chr 7:47,602,192...47,608,970
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G |
CST3 |
cystatin C |
affects expression |
EXP |
Progesterone affects the expression of CST3 mRNA |
CTD |
PMID:20107207 |
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NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590
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G |
CTSB |
cathepsin B |
increases expression |
EXP |
Progesterone results in increased expression of CTSB mRNA |
CTD |
PMID:20107207 |
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NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877
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G |
CTSL |
cathepsin L |
increases expression |
EXP |
Progesterone results in increased expression of CTSL mRNA |
CTD |
PMID:20107207 |
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NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618
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G |
EGFR |
epidermal growth factor receptor |
affects chemical synthesis |
EXP |
EGFR protein affects the chemical synthesis of Progesterone |
CTD |
PMID:21520325 |
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NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
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G |
FGF2 |
fibroblast growth factor 2 |
multiple interactions |
EXP |
Progesterone inhibits the reaction [estrone benzoate results in decreased expression of FGF2 mRNA] |
CTD |
PMID:15120423 |
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NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916
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G |
FGFR1 |
fibroblast growth factor receptor 1 |
multiple interactions decreases expression |
EXP |
estrone benzoate inhibits the reaction [Progesterone results in decreased expression of FGFR1 mRNA alternative form] |
CTD |
PMID:15120423 |
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NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724
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G |
FGFR2 |
fibroblast growth factor receptor 2 |
decreases expression multiple interactions |
EXP |
Progesterone results in decreased expression of FGFR2 mRNA alternative form [Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of FGFR2 mRNA alternative form |
CTD |
PMID:15120423 PMID:15976484 |
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NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
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G |
FSHB |
follicle stimulating hormone subunit beta |
increases chemical synthesis increases abundance multiple interactions |
EXP |
FSHB protein results in increased chemical synthesis of Progesterone FSHB protein results in increased abundance of Progesterone 4,4'-bisphenol F inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; [FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone; [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone; bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; bisphenol S inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone; Lapatinib inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; Zearalenone promotes the reaction [FSHB protein results in increased abundance of Progesterone] |
CTD |
PMID:17656051 PMID:20390873 PMID:20965553 PMID:23375200 PMID:29544186 PMID:34019995 More...
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NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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G |
GHRL |
ghrelin and obestatin prepropeptide |
multiple interactions decreases secretion increases secretion |
EXP |
Aminoglutethimide promotes the reaction [GHRL protein results in decreased secretion of Progesterone]; GHRL protein results in decreased chemical synthesis of and results in decreased secretion of Progesterone; STAT1 protein inhibits the reaction [GHRL protein results in decreased secretion of Progesterone] GHRL protein results in increased secretion of Progesterone |
CTD |
PMID:17904772 PMID:19528263 PMID:22341706 |
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NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917
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G |
HOXA10 |
homeobox A10 |
increases expression multiple interactions |
EXP |
Progesterone results in increased expression of HOXA10 mRNA Estradiol promotes the reaction [Progesterone results in increased expression of HOXA10 mRNA] |
CTD |
PMID:21705055 |
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NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257
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G |
IGF1 |
insulin like growth factor 1 |
multiple interactions increases abundance |
EXP |
[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; Zearalenone promotes the reaction [IGF1 protein results in increased abundance of Progesterone] |
CTD |
PMID:17656051 |
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NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
LEP |
leptin |
multiple interactions increases expression increases secretion |
EXP |
[TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone Progesterone results in increased expression of LEP mRNA Progesterone results in increased secretion of LEP protein |
CTD |
PMID:22151798 PMID:23153703 |
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NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323
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G |
LHB |
luteinizing hormone subunit beta |
increases abundance multiple interactions |
EXP |
LHB protein results in increased abundance of Progesterone daidzein inhibits the reaction [LHB protein results in increased abundance of Progesterone]; Lapatinib inhibits the reaction [LHB protein results in increased abundance of Progesterone] |
CTD |
PMID:19617652 PMID:23375200 |
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NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
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G |
OXT |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
EXP |
Progesterone affects the reaction [OXT protein results in increased abundance of Calcium]; Progesterone inhibits the reaction [OXT protein results in increased abundance of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprostone]; Progesterone inhibits the reaction [OXT protein results in increased transport of Calcium] |
CTD |
PMID:16997130 PMID:21370738 |
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NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546
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G |
PLAU |
plasminogen activator, urokinase |
increases expression |
EXP |
Progesterone results in increased expression of PLAU mRNA |
CTD |
PMID:23103014 |
|
NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172
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G |
POMC |
proopiomelanocortin |
increases secretion |
EXP |
POMC protein results in increased secretion of Progesterone |
CTD |
PMID:22100847 |
|
NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
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G |
RBP4 |
retinol binding protein 4 |
affects expression |
EXP |
Progesterone affects the expression of RBP4 protein |
CTD |
PMID:11833939 |
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NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765
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G |
STAT1 |
signal transducer and activator of transcription 1 |
multiple interactions |
EXP |
STAT1 protein inhibits the reaction [GHRL protein results in decreased secretion of Progesterone] |
CTD |
PMID:19528263 |
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NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
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G |
TP53 |
tumor protein p53 |
multiple interactions decreases secretion |
EXP |
[TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone TP53 protein results in decreased secretion of Progesterone |
CTD |
PMID:22151798 |
|
NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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G |
AHR |
aryl hydrocarbon receptor |
multiple interactions |
EXP |
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein] |
CTD |
PMID:12970578 |
|
NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] |
CTD |
PMID:25087994 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
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G |
CAV1 |
caveolin 1 |
multiple interactions |
EXP |
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein] |
CTD |
PMID:19608276 |
|
NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions decreases activity |
EXP |
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein] Quercetin results in decreased activity of CYP1A1 protein |
CTD |
PMID:12970578 PMID:19608276 |
|
NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
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G |
IL6 |
interleukin 6 |
multiple interactions |
EXP |
Quercetin inhibits the reaction [Linoleic Acid results in increased expression of IL6 mRNA] |
CTD |
PMID:15051824 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
MTOR |
mechanistic target of rapamycin kinase |
multiple interactions |
EXP |
Quercetin promotes the reaction [[Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:25087994 |
|
NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
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G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] |
CTD |
PMID:21375526 |
|
NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
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G |
PECAM1 |
platelet and endothelial cell adhesion molecule 1 |
multiple interactions |
EXP |
Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PECAM1 protein] |
CTD |
PMID:21375526 |
|
NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,649,044...14,723,293
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions |
EXP |
Quercetin inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein] |
CTD |
PMID:15051824 |
|
NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
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G |
SELE |
selectin E |
multiple interactions |
EXP |
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA] |
CTD |
PMID:19608276 |
|
NCBI chr 4:81,289,061...81,299,657
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G |
SELP |
selectin P |
multiple interactions |
EXP |
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELP mRNA] |
CTD |
PMID:19608276 |
|
NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955
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G |
SLC22A2 |
solute carrier family 22 member 2 |
multiple interactions |
EXP |
Quercetin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] |
CTD |
PMID:19605544 |
|
NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146
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G |
VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA] |
CTD |
PMID:15051824 PMID:19608276 |
|
NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222
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G |
SLC22A2 |
solute carrier family 22 member 2 |
multiple interactions |
EXP |
Rutin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] |
CTD |
PMID:19605544 |
|
NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146
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G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
EXP |
2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Wortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
|
NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
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G |
PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
EXP |
PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
CTD |
PMID:11514583 |
|
NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP |
Serotonin results in increased expression of FOS mRNA; Serotonin results in increased expression of FOS protein sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein] |
CTD |
PMID:11426759 |
|
NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN protein] Serotonin results in increased expression of JUN mRNA; Serotonin results in increased expression of JUN protein |
CTD |
PMID:11426759 |
|
NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation multiple interactions |
EXP |
Serotonin results in increased phosphorylation of MAPK1 protein sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:11426759 |
|
NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP |
sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:11426759 |
|
NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
multiple interactions increases secretion |
EXP |
2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; bisphenol A inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; halowax 1051 promotes the reaction [ADIPOQ protein results in increased secretion of Testosterone]; Testosterone results in decreased expression of and results in decreased secretion of ADIPOQ protein |
CTD |
PMID:28284726 |
|
NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
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G |
ADIPOR1 |
adiponectin receptor 1 |
decreases expression |
EXP |
Testosterone results in decreased expression of ADIPOR1 protein |
CTD |
PMID:28284726 |
|
NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686
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G |
ADIPOR2 |
adiponectin receptor 2 |
decreases expression |
EXP |
Testosterone results in decreased expression of ADIPOR2 protein |
CTD |
PMID:28284726 |
|
NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235
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G |
CYP19A3 |
cytochrome P450 19A3 |
multiple interactions |
EXP |
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein |
CTD |
PMID:16151981 |
|
NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
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G |
CYP3A29 |
cytochrome P450 family 3 subfamily A member 29 |
multiple interactions increases hydroxylation |
EXP |
Ketoconazole inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone] |
CTD |
PMID:20863320 |
|
NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
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G |
INS |
insulin |
multiple interactions |
EXP |
9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; [LHB protein co-treated with INS protein] results in increased abundance of Testosterone; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone] |
CTD |
PMID:11889176 |
|
NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
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G |
LHB |
luteinizing hormone subunit beta |
increases secretion multiple interactions |
EXP |
LHB protein results in increased secretion of Testosterone 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; [LHB protein co-treated with INS protein] results in increased abundance of Testosterone; Biological Products inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Cod Liver Oil inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Industrial Waste inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone] |
CTD |
PMID:11889176 PMID:26055946 |
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NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
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G |
ABCC9 |
ATP binding cassette subfamily C member 9 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ABCC9 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:51,536,531...51,673,583
Ensembl chr 5:51,536,526...51,691,595
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G |
ABCF1 |
ATP binding cassette subfamily F member 1 |
increases expression |
EXP |
Zearalenone results in increased expression of ABCF1 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr 7:23,126,255...23,144,030
Ensembl chr 7:23,126,283...23,143,994
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G |
ABLIM2 |
actin binding LIM protein family member 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ABLIM2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 8:2,948,948...3,054,974
Ensembl chr 8:2,916,775...3,054,966
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G |
ACE2 |
angiotensin converting enzyme 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ACE2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr X:12,099,849...12,152,204
Ensembl chr X:12,093,242...12,151,286
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G |
ADAM22 |
ADAM metallopeptidase domain 22 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADAM22 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:68,253,023...68,490,327
Ensembl chr 9:68,253,065...68,487,619
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G |
ADAM33 |
ADAM metallopeptidase domain 33 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADAM33 mRNA |
CTD |
PMID:34933075 |
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NCBI chr17:32,023,102...32,038,464
Ensembl chr17:32,023,091...32,037,880
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G |
ADAMTS18 |
ADAM metallopeptidase with thrombospondin type 1 motif 18 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADAMTS18 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:10,488,504...10,652,508
Ensembl chr 6:10,488,374...10,652,504
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G |
ADAMTS20 |
ADAM metallopeptidase with thrombospondin type 1 motif 20 |
increases expression |
EXP |
Zearalenone results in increased expression of ADAMTS20 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:74,502,098...74,672,703
Ensembl chr 5:74,503,113...74,672,703
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G |
ADAMTS3 |
ADAM metallopeptidase with thrombospondin type 1 motif 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADAMTS3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 8:68,675,067...68,948,537
Ensembl chr 8:68,675,070...68,948,414
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G |
ADAMTSL1 |
ADAMTS like 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADAMTSL1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:203,936,654...204,944,236
Ensembl chr 1:203,936,657...204,942,412
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G |
ADCY5 |
adenylate cyclase 5 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADCY5 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr13:136,965,746...137,133,795
Ensembl chr13:136,972,801...137,135,347
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G |
ADCYAP1R1 |
ADCYAP receptor type I |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADCYAP1R1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr18:41,915,180...41,972,327
Ensembl chr18:41,917,428...41,972,301
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G |
ADGRE5 |
adhesion G protein-coupled receptor E5 |
increases expression |
EXP |
Zearalenone results in increased expression of ADGRE5 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr 2:64,844,793...64,862,231
Ensembl chr 2:64,844,798...64,890,939
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G |
ADRA2A |
adrenoceptor alpha 2A |
decreases expression |
EXP |
Zearalenone results in decreased expression of ADRA2A mRNA |
CTD |
PMID:34933075 |
|
NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924
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G |
AIFM2 |
apoptosis inducing factor mitochondria associated 2 |
increases expression |
EXP |
Zearalenone results in increased expression of AIFM2 mRNA |
CTD |
PMID:25455459 |
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NCBI chr14:73,054,433...73,074,605
Ensembl chr14:73,055,228...73,074,567
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G |
AKR1C1 |
aldo-keto reductase family 1, member C1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of AKR1C1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248
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G |
ALDH1A3 |
aldehyde dehydrogenase 1 family member A3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ALDH1A3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:139,451,080...139,491,514
Ensembl chr 1:139,451,049...139,491,511
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G |
ALDH3A1 |
aldehyde dehydrogenase 3 family member A1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ALDH3A1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr12:59,895,476...59,905,900
Ensembl chr12:59,897,496...59,905,897
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G |
ANGPT4 |
angiopoietin 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ANGPT4 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr17:34,345,926...34,394,977
Ensembl chr17:34,348,556...34,402,851
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G |
ANXA8 |
annexin A8 |
increases expression |
EXP |
Zearalenone results in increased expression of ANXA8 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr14:88,319,209...88,340,716
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G |
APAF1 |
apoptotic peptidase activating factor 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of APAF1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
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G |
ARHGAP20 |
Rho GTPase activating protein 20 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ARHGAP20 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:38,471,049...38,582,221
Ensembl chr 9:38,474,865...38,582,242
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G |
ASPN |
asporin |
decreases expression |
EXP |
Zearalenone results in decreased expression of ASPN mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:42,165,553...42,192,902
Ensembl chr 3:42,165,561...42,192,813
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G |
ASTN1 |
astrotactin 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ASTN1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:118,649,144...118,969,032
Ensembl chr 9:118,646,910...118,968,970
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G |
ATP1A2 |
ATPase Na+/K+ transporting subunit alpha 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ATP1A2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,341,322...90,370,996
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G |
AUTS2 |
activator of transcription and developmental regulator AUTS2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of AUTS2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:13,565,439...14,794,365
Ensembl chr 3:13,565,281...14,794,365
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|
G |
AVPR1A |
vasopressin receptor 1A |
decreases expression |
EXP |
Zearalenone results in decreased expression of AVPR1A mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:27,824,991...27,832,794
Ensembl chr 5:27,824,992...27,832,703
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G |
BAALC |
BAALC binder of MAP3K1 and KLF4 |
increases expression |
EXP |
Zearalenone results in increased expression of BAALC mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:33,894,240...33,983,920
Ensembl chr 4:33,892,079...33,984,121
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|
G |
BAIAP3 |
BAI1 associated protein 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of BAIAP3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:40,536,557...40,550,508
Ensembl chr 3:40,537,399...40,550,471
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression multiple interactions |
EXP |
Zearalenone results in decreased expression of BCL2 mRNA [Acetylcysteine co-treated with Zearalenone co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone] results in increased expression of BCL2 protein; [fumonisin B1 co-treated with Zearalenone co-treated with deoxynivalenol] results in decreased expression of BCL2 protein; [fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]]; fumonisin B1 inhibits the reaction [Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]]; Zearalenone inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]] |
CTD |
PMID:29109043 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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|
G |
BMP15 |
bone morphogenetic protein 15 |
multiple interactions decreases expression |
EXP |
Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of BMP15 mRNA] |
CTD |
PMID:26386189 |
|
NCBI chr X:44,613,122...44,620,575
Ensembl chr X:44,613,122...44,620,575
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|
G |
BMP2 |
bone morphogenetic protein 2 |
affects expression |
EXP |
Zearalenone affects the expression of BMP2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195
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G |
BOK |
BCL2 family apoptosis regulator BOK |
increases expression |
EXP |
Zearalenone results in increased expression of BOK mRNA |
CTD |
PMID:34933075 |
|
NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121
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|
G |
BPIFC |
BPI fold containing family C |
decreases expression |
EXP |
Zearalenone results in decreased expression of BPIFC mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:12,526,928...12,578,958
Ensembl chr 5:12,525,806...12,578,954
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G |
C3 |
complement C3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of C3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228
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|
G |
C3H16orf89 |
chromosome 3 C16orf89 homolog |
increases expression |
EXP |
Zearalenone results in increased expression of C3H16ORF89 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:37,346,530...37,365,367
Ensembl chr 3:37,346,532...37,365,357
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G |
C4A |
complement C4A (Rodgers blood group) |
decreases expression |
EXP |
Zearalenone results in decreased expression of C4A mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 7:24,068,019...24,083,060
Ensembl chr 7:24,068,013...24,083,065
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|
G |
C4BPA |
complement component 4 binding protein alpha |
decreases expression |
EXP |
Zearalenone results in decreased expression of C4BPA mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:67,726,159...67,774,369
Ensembl chr 9:67,731,179...67,776,115
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|
G |
CA11 |
carbonic anhydrase 11 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CA11 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:53,993,183...53,999,357
Ensembl chr 6:53,993,394...53,999,172
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G |
CACNA1E |
calcium voltage-gated channel subunit alpha1 E |
decreases expression |
EXP |
Zearalenone results in decreased expression of CACNA1E mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:122,827,386...123,318,372
Ensembl chr 9:123,006,195...123,315,319
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G |
CACNA1G |
calcium voltage-gated channel subunit alpha1 G |
decreases expression |
EXP |
Zearalenone results in decreased expression of CACNA1G mRNA |
CTD |
PMID:34933075 |
|
NCBI chr12:26,838,633...26,912,344
Ensembl chr12:26,844,079...26,912,110
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G |
CACNA1H |
calcium voltage-gated channel subunit alpha1 H |
decreases expression |
EXP |
Zearalenone results in decreased expression of CACNA1H mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,427...40,695,177
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G |
CASP1 |
caspase 1, apoptosis-related cysteine peptidase |
increases expression multiple interactions |
EXP |
Zearalenone results in increased expression of CASP1 mRNA; Zearalenone results in increased expression of CASP1 protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 mRNA] |
CTD |
PMID:30270565 |
|
NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
|
|
G |
CASP3 |
caspase 3 |
multiple interactions increases expression |
EXP |
[Acetylcysteine co-treated with Zearalenone] results in decreased expression of CASP3 protein; [fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]; [fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein] |
CTD |
PMID:29109043 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CAT |
catalase |
increases expression |
EXP |
Zearalenone results in increased expression of CAT mRNA |
CTD |
PMID:23727178 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CCDC158 |
coiled-coil domain containing 158 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CCDC158 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 8:71,990,113...72,088,966
Ensembl chr 8:71,990,119...72,088,829
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G |
CCKBR |
cholecystokinin B receptor |
increases expression |
EXP |
Zearalenone results in increased expression of CCKBR mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:3,409,222...3,419,513
|
|
G |
CCL2 |
chemokine (C-C motif) ligand 2 |
multiple interactions increases expression |
EXP |
[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA Zearalenone results in increased expression of CCL2 mRNA; Zearalenone results in increased expression of CCL2 protein |
CTD |
PMID:23688591 PMID:29758222 |
|
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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G |
CCL20 |
C-C motif chemokine ligand 20 |
increases expression |
EXP |
Zearalenone results in increased expression of CCL20 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr15:129,172,743...129,176,069
|
|
G |
CCL21 |
C-C motif chemokine ligand 21 |
increases expression |
EXP |
Zearalenone results in increased expression of CCL21 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr10:32,093,783...32,094,482
Ensembl chr10:32,093,763...32,096,224
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G |
CCNB1 |
cyclin B1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CCNB1 mRNA; Zearalenone results in decreased expression of CCNB1 protein |
CTD |
PMID:29758222 |
|
NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
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G |
CD209 |
CD209 molecule |
decreases expression |
EXP |
Zearalenone results in decreased expression of CD209 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:71,394,414...71,397,711
Ensembl chr 2:71,394,391...71,397,968
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G |
CD244 |
CD244 molecule |
increases expression |
EXP |
Zearalenone results in increased expression of CD244 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:89,668,221...89,700,974
Ensembl chr 4:89,668,239...89,700,972
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G |
CDH17 |
cadherin 17 |
affects expression |
EXP |
Zearalenone affects the expression of CDH17 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:42,508,852...42,597,888
Ensembl chr 4:42,515,276...42,597,772
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G |
CDK1 |
cyclin dependent kinase 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CDK1 mRNA; Zearalenone results in decreased expression of CDK1 protein |
CTD |
PMID:29758222 |
|
NCBI chr14:64,233,945...64,255,290
Ensembl chr14:64,233,987...64,372,197
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|
G |
CDRT4 |
CMT1A duplicated region transcript 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CDRT4 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr12:58,816,336...58,881,611
|
|
G |
CFP |
complement factor properdin |
decreases expression |
EXP |
Zearalenone results in decreased expression of ELK1 mRNA; Zearalenone results in decreased expression of ELK1 protein |
CTD |
PMID:32439583 |
|
NCBI chr X:42,157,980...42,174,964
Ensembl chr X:42,157,988...42,174,951
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G |
CHP2 |
calcineurin like EF-hand protein 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CHP2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:22,473,241...22,478,697
Ensembl chr 3:22,473,247...22,478,588
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G |
CLDN1 |
claudin 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CLDN1 protein |
CTD |
PMID:32783910 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
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G |
CLEC4G |
C-type lectin domain family 4 member G |
decreases expression |
EXP |
Zearalenone results in decreased expression of CLEC4G mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:71,433,406...71,436,570
Ensembl chr 2:71,433,421...71,436,567
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G |
CLIC3 |
chloride intracellular channel 3 |
increases expression |
EXP |
Zearalenone results in increased expression of CLIC3 mRNA |
CTD |
PMID:34933075 |
|
|
|
G |
CMKLR2 |
chemerin chemokine-like receptor 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CMKLR2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr15:109,467,078...109,528,931
Ensembl chr15:109,467,080...109,521,100
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G |
CNTN4 |
contactin 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CNTN4 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr13:58,642,653...59,642,134
Ensembl chr13:58,974,198...59,642,130
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G |
COLGALT2 |
collagen beta(1-O)galactosyltransferase 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of COLGALT2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:125,149,806...125,291,092
Ensembl chr 9:125,148,753...125,291,057
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G |
CPA1 |
carboxypeptidase A1 |
increases expression |
EXP |
Zearalenone results in increased expression of CPA1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr18:18,466,564...18,482,099
Ensembl chr18:18,469,921...18,476,327
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G |
CPAMD8 |
C3 and PZP like alpha-2-macroglobulin domain containing 8 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CPAMD8 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:60,636,025...60,742,120
Ensembl chr 2:60,636,047...60,742,137
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G |
CPED1 |
cadherin like and PC-esterase domain containing 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CPED1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr18:25,655,730...25,937,923
Ensembl chr18:25,655,735...25,937,232
|
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G |
CXCL13 |
C-X-C motif chemokine ligand 13 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CXCL13 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 8:73,071,261...73,077,342
|
|
G |
CXCL14 |
C-X-C motif chemokine ligand 14 |
increases expression |
EXP |
Zearalenone results in increased expression of CXCL14 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:137,803,988...137,813,118
Ensembl chr 2:137,803,992...137,813,118
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
increases expression decreases secretion multiple interactions |
EXP |
Zearalenone results in increased expression of CXCL8 mRNA Zearalenone results in decreased secretion of CXCL8 protein [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA |
CTD |
PMID:21763767 PMID:23688591 PMID:34933075 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
|
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G |
CXCR2 |
C-X-C motif chemokine receptor 2 |
increases expression |
EXP |
Zearalenone results in increased expression of CXCR2 mRNA; Zearalenone results in increased expression of CXCR2 protein |
CTD |
PMID:29758222 |
|
NCBI chr15:120,219,657...120,230,203
|
|
G |
CYCS |
cytochrome c, somatic |
increases expression multiple interactions |
EXP |
Zearalenone results in increased expression of CYCS mRNA [Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA] |
CTD |
PMID:29109043 |
|
NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
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G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
multiple interactions |
EXP |
Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA] |
CTD |
PMID:17656051 |
|
NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
|
|
G |
CYP19A3 |
cytochrome P450 19A3 |
multiple interactions decreases expression |
EXP |
Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA] Zearalenone results in decreased expression of CYP19A1 protein |
CTD |
PMID:17656051 PMID:29758222 |
|
NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
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|
G |
CYP21A1 |
cytochrome P450 family 21 subfamily A member 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of CYP21A1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 7:24,086,138...24,089,364
Ensembl chr 7:24,086,218...24,089,370
|
|
G |
CYP4F22 |
cytochrome P450 family 4 subfamily F member 22 |
increases expression |
EXP |
Zearalenone results in increased expression of CYP4F22 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:62,078,403...62,110,891
Ensembl chr 2:62,081,269...62,110,899
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|
G |
DDIT4 |
DNA damage inducible transcript 4 |
increases expression |
EXP |
Zearalenone results in increased expression of DDIT4 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr14:75,117,708...75,119,907
Ensembl chr14:75,117,710...75,119,902
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|
G |
DEFB1 |
defensin beta 1 |
increases expression |
EXP |
Zearalenone results in increased expression of DEFB1 mRNA |
CTD |
PMID:34933075 |
|
|
|
G |
DEGS2 |
delta 4-desaturase, sphingolipid 2 |
increases expression |
EXP |
Zearalenone results in increased expression of DEGS2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 7:121,058,102...121,131,612
Ensembl chr 7:121,058,105...121,076,328
|
|
G |
DKK1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of DKK1 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,288
|
|
G |
DLG2 |
discs large MAGUK scaffold protein 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of DLG2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:17,575,991...19,547,417
Ensembl chr 9:17,576,135...19,545,916
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|
G |
DLG4 |
discs large MAGUK scaffold protein 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of DLG4 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr12:52,550,138...52,574,021
Ensembl chr12:52,550,141...52,575,143
|
|
G |
DLK1 |
delta like non-canonical Notch ligand 1 |
increases expression |
EXP |
Zearalenone results in increased expression of DLK1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 7:121,565,844...121,577,493
Ensembl chr 7:121,565,854...121,576,654
|
|
G |
DNASE1L2 |
deoxyribonuclease 1 like 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of DNASE1L2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:39,757,725...39,761,497
Ensembl chr 3:39,757,296...39,761,080
|
|
G |
DNM1 |
dynamin 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of DNM1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:268,653,045...268,702,233
Ensembl chr 1:268,653,070...268,702,222
|
|
G |
DSG3 |
desmoglein 3 |
increases expression |
EXP |
Zearalenone results in increased expression of DSG3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:115,352,005...115,383,750
Ensembl chr 6:115,351,925...115,383,743
|
|
G |
EBF3 |
EBF transcription factor 3 |
increases expression |
EXP |
Zearalenone results in increased expression of EBF3 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr14:138,819,846...138,935,504
Ensembl chr14:138,819,848...138,935,462
|
|
G |
ELF5 |
E74 like ETS transcription factor 5 |
affects expression |
EXP |
Zearalenone affects the expression of ELF5 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:26,443,979...26,486,802
Ensembl chr 2:26,443,977...26,485,903
|
|
G |
EPYC |
epiphycan |
decreases expression |
EXP |
Zearalenone results in decreased expression of EPYC mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:91,837,672...91,877,779
Ensembl chr 5:91,832,291...91,877,982
|
|
G |
ESR1 |
estrogen receptor 1 |
increases expression |
EXP |
Zearalenone results in increased expression of ESR1 mRNA |
CTD |
PMID:22484360 |
|
NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
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G |
EXTL1 |
exostosin like glycosyltransferase 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of EXTL1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:83,461,421...83,476,601
Ensembl chr 6:83,462,323...83,476,596
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|
G |
FAM184B |
family with sequence similarity 184 member B |
increases expression |
EXP |
Zearalenone results in increased expression of FAM184B mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 8:12,635,359...12,741,482
Ensembl chr 8:12,634,377...12,741,488
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G |
FIBCD1 |
fibrinogen C domain containing 1 |
increases expression |
EXP |
Zearalenone results in increased expression of FIBCD1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:270,919,793...270,956,753
Ensembl chr 1:270,918,251...270,956,347
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G |
FMO1 |
flavin containing dimethylaniline monoxygenase 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of FMO1 mRNA |
CTD |
PMID:25455459 PMID:34933075 |
|
NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076
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G |
FNDC4 |
fibronectin type III domain containing 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of FNDC4 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:111,677,569...111,682,496
Ensembl chr 3:111,678,892...111,682,426
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G |
FRMPD4 |
FERM and PDZ domain containing 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of FRMPD4 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr X:8,625,039...9,451,433
Ensembl chr X:8,542,382...9,438,821
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]; Zearalenone promotes the reaction [FSHB protein results in increased abundance of Progesterone] |
CTD |
PMID:17656051 |
|
NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
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|
G |
FST |
follistatin |
decreases expression |
EXP |
Zearalenone results in decreased expression of FST mRNA |
CTD |
PMID:25455459 |
|
NCBI chr16:32,806,341...32,811,382
Ensembl chr16:32,805,932...32,811,421
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G |
GALNT12 |
polypeptide N-acetylgalactosaminyltransferase 12 |
affects expression |
EXP |
Zearalenone affects the expression of GALNT12 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:240,595,423...240,639,625
Ensembl chr 1:240,595,394...240,640,563
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G |
GALNT6 |
polypeptide N-acetylgalactosaminyltransferase 6 |
increases expression |
EXP |
Zearalenone results in increased expression of GALNT6 mRNA |
CTD |
PMID:34933075 |
|
|
|
G |
GALR1 |
galanin receptor 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GALR1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:147,442,977...147,466,731
Ensembl chr 1:147,443,821...147,463,542
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
affects expression increases expression |
EXP |
Zearalenone affects the expression of GCLC protein Zearalenone results in increased expression of GCLC mRNA |
CTD |
PMID:31760079 |
|
NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
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|
G |
GCLM |
glutamate-cysteine ligase modifier subunit |
affects expression increases expression |
EXP |
Zearalenone affects the expression of GCLM mRNA; Zearalenone affects the expression of GCLM protein Zearalenone results in increased expression of GCLM mRNA |
CTD |
PMID:31760079 |
|
NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
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|
G |
GCNT3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
decreases expression |
EXP |
Zearalenone results in decreased expression of GCNT3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 1:112,424,212...112,540,984
Ensembl chr 1:112,422,879...112,540,983
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|
G |
GDF7 |
growth differentiation factor 7 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GDF7 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:117,586,188...117,592,541
Ensembl chr 3:117,587,430...117,592,466
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|
G |
GDF9 |
growth differentiation factor 9 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GDF9 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr 2:135,181,494...135,184,451
Ensembl chr 2:135,181,089...135,187,026
|
|
G |
GDPD1 |
glycerophosphodiester phosphodiesterase domain containing 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GDPD1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr12:35,481,194...35,527,588
Ensembl chr12:35,481,215...35,528,092
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|
G |
GJA1 |
gap junction protein alpha 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GJA1 mRNA |
CTD |
PMID:26386189 |
|
NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156
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|
G |
GJA4 |
gap junction protein alpha 4 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GJA4 mRNA |
CTD |
PMID:26386189 |
|
NCBI chr 6:91,045,430...91,048,161
Ensembl chr 6:91,045,394...91,048,162
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|
G |
GLI2 |
GLI family zinc finger 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GLI2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306
|
|
G |
GLT6D1 |
glycosyltransferase 6 domain containing 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GLT6D1 mRNA |
CTD |
PMID:34933075 |
|
|
|
G |
GNAI2 |
G protein subunit alpha i2 |
increases expression |
EXP |
Zearalenone results in increased expression of GNAI2 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr13:32,705,326...32,733,804
Ensembl chr13:32,705,321...32,733,794
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G |
GNAO1 |
G protein subunit alpha o1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GNAO1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:29,416,574...29,592,874
Ensembl chr 6:29,417,603...29,592,706
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G |
GPX1 |
glutathione peroxidase 1 |
increases expression |
EXP |
Zearalenone results in increased expression of GPX1 mRNA; Zearalenone results in increased expression of GPX1 protein |
CTD |
PMID:23727178 PMID:31760079 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GPX6 |
glutathione peroxidase 6 |
increases expression |
EXP |
Zearalenone results in increased expression of GPX6 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr 7:22,256,013...22,267,992
Ensembl chr 7:22,256,038...22,267,992
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|
G |
GRB10 |
growth factor receptor bound protein 10 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GRB10 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr 9:136,580,363...136,742,552
Ensembl chr 9:136,580,362...136,741,756
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G |
GRID2 |
glutamate ionotropic receptor delta type subunit 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GRID2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 8:125,821,195...127,130,617
Ensembl chr 8:125,819,951...127,129,763
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions |
EXP |
Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]] |
CTD |
PMID:29109043 |
|
NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
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G |
GTF3C4 |
general transcription factor IIIC subunit 4 |
increases expression |
EXP |
Zearalenone results in increased expression of GTF3C4 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr 1:272,454,488...272,479,968
Ensembl chr 1:272,454,503...272,479,965
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G |
GTSF1 |
gametocyte specific factor 1 |
increases expression |
EXP |
Zearalenone results in increased expression of GTSF1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:19,639,326...19,661,773
Ensembl chr 5:19,645,135...19,661,599
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|
G |
HEPH |
hephaestin |
increases expression |
EXP |
Zearalenone results in increased expression of HEPH mRNA |
CTD |
PMID:34933075 |
|
NCBI chr X:52,314,911...52,397,384
Ensembl chr X:52,314,935...52,397,380
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|
G |
HMOX1 |
heme oxygenase 1 |
affects expression decreases expression multiple interactions |
EXP |
Zearalenone affects the expression of HMOX1 mRNA; Zearalenone affects the expression of HMOX1 protein Zearalenone results in decreased expression of HMOX1 mRNA; Zearalenone results in decreased expression of HMOX1 protein [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein] |
CTD |
PMID:31760079 PMID:35489465 |
|
|
|
G |
HOXA10 |
homeobox A10 |
decreases expression |
EXP |
Zearalenone results in decreased expression of HOXA10 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257
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|
G |
IFNG |
interferon gamma |
multiple interactions increases expression |
EXP |
[Zearalenone co-treated with deoxynivalenol] results in decreased expression of IFNG mRNA; Zearalenone results in decreased expression of and results in decreased secretion of IFNG protein; Zearalenone results in increased expression of and results in increased secretion of IFNG protein Zearalenone results in increased expression of IFNG mRNA |
CTD |
PMID:18296887 PMID:23727178 PMID:34933075 |
|
NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
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|
G |
IGF1 |
insulin like growth factor 1 |
decreases expression multiple interactions |
EXP |
Zearalenone results in decreased expression of IGF1 mRNA; Zearalenone results in decreased expression of IGF1 protein Zearalenone affects the reaction [IGF1 protein results in increased abundance of Estradiol]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]; Zearalenone promotes the reaction [IGF1 protein results in increased abundance of Progesterone] |
CTD |
PMID:17656051 PMID:29758222 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
|
|
G |
IGFBP5 |
insulin like growth factor binding protein 5 |
decreases expression |
EXP |
Zearalenone results in decreased expression of IGFBP5 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr15:118,861,816...118,877,787
Ensembl chr15:118,857,625...118,878,120
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|
G |
IGSF3 |
immunoglobulin superfamily member 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of IGSF3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:104,044,784...104,167,173
Ensembl chr 4:103,994,390...104,166,988
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|
G |
IGSF5 |
immunoglobulin superfamily member 5 |
increases expression |
EXP |
Zearalenone results in increased expression of IGSF5 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr13:203,325,385...203,372,361
|
|
G |
IGSF9B |
immunoglobulin superfamily member 9B |
decreases expression |
EXP |
Zearalenone results in decreased expression of IGSF9B mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 9:60,467,321...60,521,463
Ensembl chr 9:60,478,029...60,521,465
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|
G |
IL10 |
interleukin 10 |
multiple interactions decreases expression increases expression |
EXP |
Zearalenone results in decreased expression of and results in decreased secretion of IL10 protein Zearalenone results in decreased expression of IL10 mRNA Zearalenone results in increased expression of IL10 protein |
CTD |
PMID:23727178 PMID:34933075 |
|
NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
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|
G |
IL18 |
interleukin 18 |
multiple interactions increases expression |
EXP |
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA] |
CTD |
PMID:25455459 PMID:30270565 |
|
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
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|
G |
IL1A |
interleukin 1 alpha |
multiple interactions increases expression |
EXP |
[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA Zearalenone results in increased expression of IL1A mRNA |
CTD |
PMID:23688591 |
|
NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121
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G |
IL2 |
interleukin 2 |
multiple interactions increases expression |
EXP |
[Zearalenone co-treated with deoxynivalenol] results in decreased expression of IL2 mRNA Zearalenone results in increased expression of IL2 mRNA |
CTD |
PMID:18296887 PMID:34933075 |
|
NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
|
|
G |
IL22RA1 |
interleukin 22 receptor subunit alpha 1 |
increases expression |
EXP |
Zearalenone results in increased expression of IL22RA1 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:81,867,849...81,885,017
Ensembl chr 6:81,867,848...81,884,996
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|
G |
IL23R |
interleukin 23 receptor |
decreases expression |
EXP |
Zearalenone results in decreased expression of IL23R mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510
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G |
IL4 |
interleukin 4 |
multiple interactions |
EXP |
Zearalenone results in decreased expression of and results in decreased secretion of IL4 protein |
CTD |
PMID:23727178 |
|
NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
|
|
G |
IL6 |
interleukin 6 |
increases expression multiple interactions |
EXP |
Zearalenone results in increased expression of IL6 mRNA; Zearalenone results in increased expression of IL6 protein [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of IL6 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of IL6 protein] |
CTD |
PMID:23688591 PMID:32783910 PMID:34933075 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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|
G |
INHBA |
inhibin subunit beta A |
increases expression |
EXP |
Zearalenone results in increased expression of INHBA mRNA |
CTD |
PMID:25455459 |
|
NCBI chr12:53,115,379...53,117,128 NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967
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|
G |
IP6K3 |
inositol hexakisphosphate kinase 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of IP6K3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 7:29,938,779...29,961,520
Ensembl chr 7:29,931,925...29,961,466
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|
G |
IRX3 |
iroquois homeobox 3 |
increases expression |
EXP |
Zearalenone results in increased expression of IRX3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:31,044,919...31,049,067
Ensembl chr 6:31,046,146...31,049,054
|
|
G |
ISLR2 |
immunoglobulin superfamily containing leucine rich repeat 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ISLR2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 7:59,385,021...59,393,185
Ensembl chr 7:59,386,241...59,388,481
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|
G |
ITGB5 |
integrin subunit beta 5 |
increases expression |
EXP |
Zearalenone results in increased expression of ITGB5 mRNA |
CTD |
PMID:25455459 |
|
NCBI chr13:135,468,111...135,587,483
Ensembl chr13:135,467,798...135,587,473
|
|
G |
JADE2 |
jade family PHD finger 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of JADE2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:136,686,056...136,832,004
Ensembl chr 2:136,788,372...136,832,001
|
|
G |
JAKMIP2 |
janus kinase and microtubule interacting protein 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of JAKMIP2 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 2:148,864,445...149,045,921
Ensembl chr 2:148,861,751...149,045,927
|
|
G |
KCND3 |
potassium voltage-gated channel subfamily D member 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of KCND3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:108,394,687...108,621,514
Ensembl chr 4:108,246,237...108,621,510
|
|
G |
KCNK3 |
potassium two pore domain channel subfamily K member 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of KCNK3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 3:112,322,446...112,359,212
Ensembl chr 3:112,322,446...112,359,212
|
|
G |
KEAP1 |
kelch like ECH associated protein 1 |
affects expression decreases expression |
EXP |
Zearalenone affects the expression of KEAP1 protein Zearalenone results in decreased expression of KEAP1 mRNA |
CTD |
PMID:31760079 |
|
NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
|
|
G |
KHDRBS3 |
KH RNA binding domain containing, signal transduction associated 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of KHDRBS3 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 4:6,289,577...6,446,494
Ensembl chr 4:6,282,076...6,446,389
|
|
G |
KIAA1210 |
KIAA1210 ortholog |
decreases expression |
EXP |
Zearalenone results in decreased expression of KIAA1210 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr X:97,581,400...97,651,765
|
|
G |
KIT |
KIT proto-oncogene, receptor tyrosine kinase |
decreases expression |
EXP |
Zearalenone results in decreased expression of KIT mRNA |
CTD |
PMID:26386189 |
|
NCBI chr 8:41,402,334...41,492,306
Ensembl chr 8:41,402,043...41,493,734
|
|
G |
KLHDC7A |
kelch domain containing 7A |
decreases expression |
EXP |
Zearalenone results in decreased expression of KLHDC7A mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 6:77,022,168...77,030,776
Ensembl chr 6:77,023,865...77,026,255
|
|
G |
KRT18 |
keratin 18 |
increases expression |
EXP |
Zearalenone results in increased expression of KRT18 mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:18,217,686...18,221,432
Ensembl chr 5:18,217,691...18,221,429
|
|
G |
KRT6A |
keratin 6A |
increases expression |
EXP |
Zearalenone results in increased expression of KRT6A mRNA |
CTD |
PMID:34933075 |
|
NCBI chr 5:17,830,147...17,851,113
Ensembl chr 5:17,780,928...17,868,402
|
|
G |
KRT8 |
keratin 8 |
increases expression |
EXP |
Zearalenone results in increased expression of KRT8 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 5:18,172,423...18,180,277
Ensembl chr 5:18,167,553...18,180,404
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G |
LAMC3 |
laminin subunit gamma 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of LAMC3 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 1:271,004,423...271,071,223
Ensembl chr 1:271,004,433...271,071,223
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G |
LGI2 |
leucine rich repeat LGI family member 2 |
increases expression |
EXP |
Zearalenone results in increased expression of LGI2 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 8:18,986,549...19,017,238
Ensembl chr 8:18,986,046...19,017,431
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G |
LGR5 |
leucine rich repeat containing G protein-coupled receptor 5 |
increases expression |
EXP |
Zearalenone results in increased expression of LGR5 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 5:35,463,257...35,595,234
Ensembl chr 5:35,463,279...35,595,930
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G |
LOC106504562 |
glutathione S-transferase alpha M14 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GSTA1 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 7:46,553,813...46,567,596
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G |
LOC110255234 |
liver carboxylesterase-like |
increases expression |
EXP |
Zearalenone results in increased expression of CES1 mRNA |
CTD |
PMID:34933075 |
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions increases expression |
EXP |
[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of IL1B protein]; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; Zearalenone results in decreased expression of and results in decreased secretion of IL1B protein; Zearalenone results in increased expression of and results in increased secretion of IL1B protein Zearalenone results in increased expression of IL1B mRNA; Zearalenone results in increased expression of IL1B protein |
CTD |
PMID:23688591 PMID:23727178 PMID:30270565 PMID:32783910 PMID:34933075 |
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G |
LRFN3 |
leucine rich repeat and fibronectin type III domain containing 3 |
decreases expression |
EXP |
Zearalenone results in decreased expression of LRFN3 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 6:45,343,846...45,352,779
Ensembl chr 6:45,346,637...45,351,990
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G |
LRFN5 |
leucine rich repeat and fibronectin type III domain containing 5 |
decreases expression |
EXP |
Zearalenone results in decreased expression of LRFN5 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 1:171,906,130...172,177,726
Ensembl chr 1:171,906,198...172,177,720
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G |
LRRC4B |
leucine rich repeat containing 4B |
decreases expression |
EXP |
Zearalenone results in decreased expression of LRRC4B mRNA |
CTD |
PMID:34933075 |
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NCBI chr 6:55,346,787...55,409,876
Ensembl chr 6:55,346,908...55,409,991
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G |
LRTM2 |
leucine rich repeats and transmembrane domains 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of LRTM2 mRNA |
CTD |
PMID:34933075 |
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NCBI chr 5:68,821,815...68,836,518
Ensembl chr 5:68,822,539...68,836,514
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G |
MAP3K7CL |
MAP3K7 C-terminal like |
decreases expression |
EXP |
Zearalenone results in decreased expression of MAP3K7CL mRNA |
CTD |
PMID:34933075 |
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NCBI chr13:192,488,937...192,534,826
Ensembl chr13:192,489,751...192,534,821
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G |
MGP |
matrix Gla protein |
decreases expression |
EXP |
Zearalenone results in decreased expression of MGP mRNA |
CTD |
PMID:34933075 |
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NCBI chr 5:57,665,272...57,669,360
Ensembl chr 5:57,665,248...57,669,764
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G |
MIR331 |
microRNA mir-331 |
increases expression |
EXP |
Zearalenone results in increased expression of MIR331 mRNA |
CTD |
PMID:32439583 |
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NCBI chr 5:88,028,339...88,028,418
Ensembl chr 5:88,028,339...88,028,418
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G |
MIR744 |
microRNA mir-744 |
increases expression |
EXP |
Zearalenone results in increased expression of MIR744 mRNA |
CTD |
PMID:32439583 |
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NCBI chr12:56,464,848...56,464,927
Ensembl chr12:56,464,848...56,464,927
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