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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:molecular messenger
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Accession:CHEBI:33280 term browser browse the term
Synonyms:related_synonym: chemical messenger



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1,3-benzothiazole-2-thiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TPO thyroid peroxidase decreases activity EXP captax results in decreased activity of TPO protein CTD PMID:23959146 PMID:25953703 NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208
JBrowse link
1,4-dithiothreitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 multiple interactions EXP Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] CTD PMID:21296058 NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Dithiothreitol metabolite results in increased expression of HSPA5 protein CTD PMID:17416481 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions EXP Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] CTD PMID:16785314 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
JBrowse link
17beta-estradiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases phosphorylation EXP Estradiol results in increased phosphorylation of ACACA protein CTD PMID:15967841 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions
increases secretion
EXP Benzo(a)pyrene inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol]; bisphenol A promotes the reaction [ADIPOQ protein results in increased secretion of Estradiol]; Estradiol results in increased expression of and results in increased secretion of ADIPOQ protein; halowax 1051 inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol]; Hexachlorobenzene inhibits the reaction [ADIPOQ protein results in increased secretion of Estradiol] CTD PMID:28284726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
JBrowse link
G ADIPOR1 adiponectin receptor 1 increases expression EXP Estradiol results in increased expression of ADIPOR1 protein CTD PMID:28284726 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686
JBrowse link
G ADIPOR2 adiponectin receptor 2 increases expression EXP Estradiol results in increased expression of ADIPOR2 protein CTD PMID:28284726 NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235
JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation EXP Estradiol results in increased phosphorylation of AKT1 protein CTD PMID:17348974
G CD40 CD40 molecule affects expression EXP Estradiol affects the expression of CD40 protein CTD PMID:15964915 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
JBrowse link
G CD40LG CD40 ligand affects expression EXP Estradiol affects the expression of CD40LG protein CTD PMID:15964915 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709
JBrowse link
G ESR1 estrogen receptor 1 decreases expression
affects expression
EXP Estradiol results in decreased expression of ESR1 protein; Estradiol results in decreased expression of ESR1 protein alternative form
Estradiol affects the expression of ESR1 protein
CTD PMID:15653758 PMID:16431846 PMID:16680078 PMID:17348974 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G ESR2 estrogen receptor 2 affects expression EXP Estradiol affects the expression of ESR2 protein CTD PMID:15653758 PMID:16680078 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565
JBrowse link
G F3 coagulation factor III, tissue factor affects expression EXP Estradiol affects the expression of F3 mRNA; Estradiol affects the expression of F3 protein CTD PMID:15964915 NCBI chr 4:122,827,018...122,837,673
Ensembl chr 4:122,826,644...122,837,666
JBrowse link
G FGF7 fibroblast growth factor 7 increases expression EXP Estradiol results in increased expression of FGF7 mRNA CTD PMID:15271478 NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions
increases chemical synthesis
EXP 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; [FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol; [FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol; bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; lead acetate inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol] CTD PMID:17656051 PMID:29273543 PMID:34019995 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G HOXA10 homeobox A10 increases expression
multiple interactions
EXP Estradiol results in increased expression of HOXA10 mRNA
Estradiol promotes the reaction [Progesterone results in increased expression of HOXA10 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of HOXA10 mRNA]
CTD PMID:21705055 NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions
increases abundance
EXP [FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol; deoxynivalenol affects the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Estradiol]; deoxynivalenol affects the reaction [IGF1 protein results in increased abundance of Estradiol]; Zearalenone affects the reaction [IGF1 protein results in increased abundance of Estradiol] CTD PMID:17656051 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G LEP leptin increases secretion
increases expression
EXP Estradiol results in increased secretion of LEP protein
Estradiol results in increased expression of LEP mRNA
CTD PMID:23153703 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323
JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions
increases secretion
EXP Biological Products inhibits the reaction [LHB protein results in increased secretion of Estradiol]; Cod Liver Oil inhibits the reaction [LHB protein results in increased secretion of Estradiol]; Industrial Waste inhibits the reaction [LHB protein results in increased secretion of Estradiol] CTD PMID:26055946 NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
JBrowse link
G MMP2 matrix metallopeptidase 2 affects secretion EXP Estradiol affects the secretion of MMP2 protein CTD PMID:15653758 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
affects expression
increases phosphorylation
decreases expression
EXP Estradiol results in increased phosphorylation of and results in increased activity of NOS3 protein; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of NOS3 protein]
Estradiol affects the expression of NOS3 mRNA
Estradiol results in decreased expression of NOS3 mRNA
CTD PMID:15653758 PMID:15967841 PMID:16680078 PMID:17618301 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
JBrowse link
G PDGFB platelet derived growth factor subunit B multiple interactions EXP Estradiol affects the secretion of [PDGFB protein binds to PDGFB protein] CTD PMID:15653758 Ensembl chr 5:8,986,462...9,007,435 JBrowse link
G PGR progesterone receptor increases expression EXP Estradiol results in increased expression of PGR mRNA CTD PMID:16431846 NCBI chr 9:32,035,684...32,129,776
Ensembl chr 9:32,035,684...32,129,221
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP Estradiol results in increased phosphorylation of and results in increased activity of PRKAA1 protein CTD PMID:15967841 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707
JBrowse link
G PRLR prolactin receptor increases expression EXP Estradiol results in increased expression of PRLR protein alternative form CTD PMID:18492821 NCBI chr16:20,637,568...20,655,881
Ensembl chr16:20,618,875...20,810,140
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP Estradiol results in increased expression of PTGS2 mRNA
Fulvestrant inhibits the reaction [Estradiol results in increased expression of PTGS2 mRNA]
CTD PMID:21705055 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G SPP1 secreted phosphoprotein 1 decreases expression EXP Estradiol results in decreased expression of SPP1 protein CTD PMID:15713688 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b increases expression EXP Estradiol results in increased expression of TNFRSF11B protein CTD PMID:15713688 NCBI chr 4:19,850,212...19,879,132
Ensembl chr 4:19,850,350...19,879,125
JBrowse link
17beta-estradiol 3-benzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF7 fibroblast growth factor 7 affects expression EXP estradiol 3-benzoate affects the expression of FGF7 mRNA CTD PMID:15976484 NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 decreases expression
multiple interactions
EXP estradiol 3-benzoate results in decreased expression of FGFR2 mRNA alternative form
[Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of FGFR2 mRNA alternative form
CTD PMID:15976484 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
JBrowse link
3,3',5,5'-tetrabromobisphenol A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGO2 argonaute RISC catalytic component 2 decreases expression
multiple interactions
EXP tetrabromobisphenol A results in decreased expression of AGO2 protein
[tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of AGO2 protein
CTD PMID:31266599 NCBI chr 4:2,966,794...3,012,388
Ensembl chr 4:2,919,511...3,015,334
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression EXP tetrabromobisphenol A results in decreased expression of AKT1 mRNA; tetrabromobisphenol A results in decreased expression of AKT1 protein CTD PMID:35665993
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases activity EXP tetrabromobisphenol A results in decreased activity of ATP2A2 protein CTD PMID:17784851 NCBI chr14:31,674,659...31,744,981
Ensembl chr14:31,674,757...31,744,969
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 decreases activity EXP tetrabromobisphenol A results in decreased activity of ATP2A3 protein CTD PMID:17784851 NCBI chr12:49,980,488...50,014,006
Ensembl chr12:49,980,497...50,025,171
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP tetrabromobisphenol A results in increased expression of BAX mRNA; tetrabromobisphenol A results in increased expression of BAX protein
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein]
CTD PMID:35665993 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP tetrabromobisphenol A results in decreased expression of BCL2 mRNA; tetrabromobisphenol A results in decreased expression of BCL2 protein CTD PMID:35665993 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions
EXP tetrabromobisphenol A results in increased expression of CASP3 mRNA; tetrabromobisphenol A results in increased expression of CASP3 protein
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 protein]
CTD PMID:35665993 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP8 caspase 8 multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 protein]
tetrabromobisphenol A results in decreased expression of CASP8 mRNA; tetrabromobisphenol A results in decreased expression of CASP8 protein
CTD PMID:35665993 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein]
tetrabromobisphenol A results in increased expression of CASP9 mRNA; tetrabromobisphenol A results in increased expression of CASP9 protein
CTD PMID:35665993 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G COX7A2L cytochrome c oxidase subunit 7A2 like increases expression
multiple interactions
EXP tetrabromobisphenol A results in increased expression of COX7A2L mRNA
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of COX7A2L mRNA]
CTD PMID:35665993 NCBI chr 3:97,951,115...97,983,309
Ensembl chr 3:97,951,114...97,983,309
JBrowse link
G DICER1 dicer 1, ribonuclease III decreases expression
multiple interactions
EXP tetrabromobisphenol A results in decreased expression of DICER1 mRNA; tetrabromobisphenol A results in decreased expression of DICER1 protein
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of DICER1 protein
CTD PMID:31266599 NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,365,802...116,411,224
JBrowse link
G DROSHA drosha ribonuclease III increases expression EXP tetrabromobisphenol A results in increased expression of DROSHA mRNA CTD PMID:31266599 NCBI chr16:17,727,695...17,847,954
Ensembl chr16:17,565,137...17,848,162
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 decreases expression
multiple interactions
EXP tetrabromobisphenol A results in decreased expression of GPER1 protein
[tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein
CTD PMID:31266599 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980
JBrowse link
G LOC100623720 collagen alpha-1(VI) chain increases expression
multiple interactions
EXP tetrabromobisphenol A results in increased expression of COL6A1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [tetrabromobisphenol A results in increased expression of COL6A1 protein]; tetrabromobisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of COL6A1 protein]
CTD PMID:31266599 NCBI chr13:208,295,245...208,321,789
Ensembl chr13:208,295,451...208,313,127
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions
increases expression
EXP [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in increased expression of MAP1LC3B protein
tetrabromobisphenol A results in increased expression of MAP1LC3B protein
CTD PMID:31266599 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase multiple interactions
increases expression
EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL protein]
tetrabromobisphenol A results in increased expression of MLKL mRNA; tetrabromobisphenol A results in increased expression of MLKL protein
CTD PMID:35665993 NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma decreases expression EXP tetrabromobisphenol A results in decreased expression of PIK3CG mRNA; tetrabromobisphenol A results in decreased expression of PIK3CG protein CTD PMID:35665993 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099
JBrowse link
G PLIN1 perilipin 1 multiple interactions
increases expression
EXP [tetrabromobisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in increased expression of PLIN1 protein
tetrabromobisphenol A results in increased expression of PLIN1 protein
CTD PMID:31266599 NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797
JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions
increases expression
EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein]
tetrabromobisphenol A results in increased expression of PTEN mRNA; tetrabromobisphenol A results in increased expression of PTEN protein
CTD PMID:35665993 NCBI chr14:99,929,590...100,021,619 JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression
multiple interactions
EXP tetrabromobisphenol A results in increased expression of RIPK1 mRNA; tetrabromobisphenol A results in increased expression of RIPK1 protein
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 protein]
CTD PMID:35665993 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 multiple interactions
increases expression
EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein]
tetrabromobisphenol A results in increased expression of RIPK3 mRNA; tetrabromobisphenol A results in increased expression of RIPK3 protein
CTD PMID:35665993 NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251
JBrowse link
G XPO5 exportin 5 multiple interactions
decreases expression
EXP [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with tetrabromobisphenol A] results in decreased expression of XPO5 protein
tetrabromobisphenol A results in decreased expression of XPO5 protein
CTD PMID:31266599 NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,531,919...38,569,582
JBrowse link
6beta-hydroxytestosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 increases chemical synthesis
multiple interactions
EXP CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone
Ketoconazole inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]
CTD PMID:20863320 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
JBrowse link
acetylsalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of HSPA5 protein] CTD PMID:20665602 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
G PLA2G1B phospholipase A2 group IB multiple interactions EXP Aspirin promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] CTD PMID:10706128 NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,520...40,322,315
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Aspirin promotes the reaction [PLA2G1B protein results in increased expression of PTGS2 mRNA] CTD PMID:10706128 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
aldosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions
increases secretion
EXP 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer inhibits the reaction [AGT protein results in increased secretion of Aldosterone]; Enkephalin, D-Penicillamine (2,5)- inhibits the reaction [AGT protein results in increased secretion of Aldosterone] CTD PMID:22100847 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Aldosterone results in increased expression of ATP1A1 protein CTD PMID:28438630 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP Aldosterone results in increased expression of GCLC protein CTD PMID:24512358 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP Aldosterone results in increased expression of HMOX1 protein CTD PMID:24512358
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo(4,5-d)pyrimidine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; acetovanillone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Aldosterone results in increased expression of and results in increased activity of NFE2L2 protein; diphenyleneiodonium inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Eplerenone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Ro 32-0432 inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; tempol inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; Thioctic Acid inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]; W 7 inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
JBrowse link
G SOD1 superoxide dismutase 1 increases expression EXP Aldosterone results in increased expression of SOD1 protein CTD PMID:24512358 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP Aldosterone results in increased expression of TXNRD1 protein CTD PMID:24512358 NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,172,260...80,236,219
JBrowse link
alfacalcidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 increases hydroxylation EXP CYP2D6 protein results in increased hydroxylation of alfacalcidol CTD PMID:11880238 NCBI chr 5:6,539,021...6,543,643
Ensembl chr 5:6,538,907...6,543,642
JBrowse link
all-trans-retinoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 chemokine (C-C motif) ligand 2 multiple interactions EXP Tretinoin promotes the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CCL2 protein] CTD PMID:21130106 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 decreases activity EXP Tretinoin results in decreased activity of GPD1 protein CTD PMID:15583048 NCBI chr 5:16,008,179...16,021,676
Ensembl chr 5:16,007,448...16,017,825
JBrowse link
G NRL neural retina leucine zipper increases expression EXP Tretinoin results in increased expression of NRL protein CTD PMID:16854989 NCBI chr 7:75,199,048...75,211,655
Ensembl chr 7:75,206,719...75,210,529
JBrowse link
androst-4-ene-3,17-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol]; [FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol; bisphenol S inhibits the reaction [[FSHB protein co-treated with Androstenedione] results in increased chemical synthesis of and results in increased secretion of Estradiol] CTD PMID:34019995 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Androstenedione] results in increased activity of HSD17B1 protein CTD PMID:16151981 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548
JBrowse link
G INS insulin multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; [LHB protein co-treated with INS protein] results in increased abundance of Androstenedione; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione] CTD PMID:11889176 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; [LHB protein co-treated with INS protein] results in increased abundance of Androstenedione; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione] CTD PMID:11889176 NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
JBrowse link
aspartame term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPEP glutamyl aminopeptidase multiple interactions
increases hydrolysis
EXP 1,10-phenanthroline inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; amastatin inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] CTD PMID:8141778 NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510
JBrowse link
betamethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMOX2 heme oxygenase 2 increases expression EXP Betamethasone results in increased expression of HMOX2 protein CTD PMID:11698254 NCBI chr 3:37,829,044...37,868,163
Ensembl chr 3:37,831,439...37,868,128
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Betamethasone results in decreased expression of PTGS2 protein CTD PMID:11698254 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
bisphenol A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 increases expression EXP bisphenol A results in increased expression of ADCYAP1 protein CTD PMID:29569701 NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions EXP bisphenol A inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]; bisphenol A inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; bisphenol A promotes the reaction [ADIPOQ protein results in increased secretion of Estradiol]; bisphenol A results in increased expression of and results in increased secretion of ADIPOQ protein CTD PMID:28284726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
JBrowse link
G ADIPOR1 adiponectin receptor 1 increases expression EXP bisphenol A results in increased expression of ADIPOR1 protein CTD PMID:28284726 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686
JBrowse link
G ADIPOR2 adiponectin receptor 2 increases expression EXP bisphenol A results in increased expression of ADIPOR2 protein CTD PMID:28284726 NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235
JBrowse link
G AGO2 argonaute RISC catalytic component 2 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of AGO2 protein
[bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of AGO2 protein
CTD PMID:31266599 NCBI chr 4:2,966,794...3,012,388
Ensembl chr 4:2,919,511...3,015,334
JBrowse link
G ALB albumin multiple interactions
decreases expression
EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of ALB protein] CTD PMID:37999554 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696
JBrowse link
G AQP3 aquaporin 3 decreases expression EXP bisphenol A results in decreased expression of AQP3 mRNA CTD PMID:32710935 NCBI chr10:33,045,374...33,050,285
Ensembl chr10:33,045,245...33,051,082
JBrowse link
G AQP4 aquaporin 4 decreases expression EXP bisphenol A results in decreased expression of AQP4 mRNA CTD PMID:32710935 NCBI chr 6:111,407,632...111,422,169
Ensembl chr 6:111,407,639...111,422,109
JBrowse link
G AQP9 aquaporin 9 affects expression EXP bisphenol A affects the expression of AQP9 mRNA CTD PMID:32710935 NCBI chr 1:113,798,380...113,848,452
Ensembl chr 1:113,794,040...113,848,683
JBrowse link
G ATF4 activating transcription factor 4 multiple interactions
increases expression
EXP Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF4 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of ATF4 mRNA]
bisphenol A results in increased expression of ATF4 mRNA; bisphenol A results in increased expression of ATF4 protein
CTD PMID:37108405 PMID:38845341 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
JBrowse link
G ATF6 activating transcription factor 6 increases expression
multiple interactions
EXP bisphenol A results in increased expression of ATF6 protein
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ATF6 protein]
CTD PMID:37108405 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP bisphenol A results in increased expression of BAX mRNA; bisphenol A results in increased expression of BAX protein
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]
CTD PMID:37108405 PMID:38845341 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
increases expression
multiple interactions
EXP bisphenol A results in decreased expression of BCL2 mRNA; bisphenol A results in decreased expression of BCL2 protein
bisphenol A results in increased expression of BCL2 mRNA
Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein]; ursodoxicoltaurine promotes the reaction [bisphenol A results in increased expression of BCL2 mRNA]
CTD PMID:28819136 PMID:37108405 PMID:38845341 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of BCL2L1 mRNA; bisphenol A results in decreased expression of BCL2L1 protein
Sodium Selenite affects the reaction [bisphenol A results in decreased expression of BCL2L1 protein]
CTD PMID:28819136 PMID:37108405 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G BECN1 beclin 1 increases expression EXP bisphenol A results in increased expression of BECN1 mRNA CTD PMID:28819136 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G CARTPT CART prepropeptide increases expression
decreases expression
EXP bisphenol A results in increased expression of CARTPT protein
bisphenol A results in decreased expression of CARTPT protein
CTD PMID:29558425 PMID:29569701 PMID:29577965 PMID:29888781 PMID:38069115 NCBI chr16:48,043,558...48,045,592
Ensembl chr16:48,043,492...48,045,592
JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
EXP [bisphenol A co-treated with fisetin] results in increased expression of CASP3 mRNA; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of CASP3 mRNA]
bisphenol A results in increased expression of CASP3 mRNA; bisphenol A results in increased expression of CASP3 protein
CTD PMID:29544186 PMID:37108405 PMID:38845341 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP8 caspase 8 multiple interactions
increases expression
EXP Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP8 mRNA] CTD PMID:37108405 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
EXP Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of CASP9 mRNA] CTD PMID:37108405 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G CAT catalase multiple interactions
decreases activity
decreases expression
EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased activity of CAT protein] CTD PMID:29129240 PMID:37108405 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP bisphenol A results in increased expression of CDKN1A protein CTD PMID:28819136 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,354,672...32,363,761
JBrowse link
G CLDN1 claudin 1 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of CLDN1 mRNA; bisphenol A results in decreased expression of CLDN1 protein
Cysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of CLDN1 protein]
CTD PMID:37108405 PMID:37999554 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions
decreases expression
EXP [bisphenol A co-treated with fisetin] results in decreased expression of CYP11A1 mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of CYP11A1 mRNA] CTD PMID:29544186 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
JBrowse link
G CYP19A3 cytochrome P450 19A3 increases expression
multiple interactions
EXP bisphenol A results in increased expression of CYP19A1 protein
bisphenol A inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]
CTD PMID:28284726 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G DBH dopamine beta-hydroxylase increases expression EXP bisphenol A results in increased expression of DBH protein CTD PMID:29888781 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,175...273,225,552
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions
EXP bisphenol A results in increased expression of DDIT3 mRNA; bisphenol A results in increased expression of DDIT3 protein
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of DDIT3 mRNA]
CTD PMID:37108405 PMID:38845341 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
JBrowse link
G DICER1 dicer 1, ribonuclease III decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of DICER1 mRNA; bisphenol A results in decreased expression of DICER1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in decreased expression of DICER1 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of DICER1 mRNA
CTD PMID:31266599 NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,365,802...116,411,224
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions
decreases expression
EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA] CTD PMID:28445388 PMID:28819136 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
JBrowse link
G DNMT3B DNA methyltransferase 3 beta decreases expression EXP bisphenol A results in decreased expression of DNMT3B mRNA CTD PMID:28819136 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072
JBrowse link
G DROSHA drosha ribonuclease III multiple interactions
decreases expression
EXP 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in decreased expression of DROSHA protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in increased expression of DROSHA mRNA; bisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of DROSHA protein] CTD PMID:31266599 NCBI chr16:17,727,695...17,847,954
Ensembl chr16:17,565,137...17,848,162
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
EXP Sodium Selenite inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2AK3 protein] CTD PMID:37108405 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions
EXP bisphenol A results in increased expression of ERN1 protein
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of ERN1 protein]
CTD PMID:37108405 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]] CTD PMID:29544186 PMID:34019995 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G GAL galanin and GMAP prepropeptide increases expression
affects expression
EXP bisphenol A results in increased expression of GAL protein
bisphenol A affects the expression of GAL protein
CTD PMID:29558425 PMID:29569701 PMID:29577965 PMID:29888781 PMID:38069115 NCBI chr 2:4,351,113...4,357,167
Ensembl chr 2:4,351,113...4,356,647
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
increases expression
EXP Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLC mRNA] CTD PMID:37999554 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
multiple interactions
EXP bisphenol A results in increased expression of GCLM mRNA
Cysteine inhibits the reaction [bisphenol A results in increased expression of GCLM mRNA]
CTD PMID:37999554 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 multiple interactions EXP [bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in decreased expression of GPER1 protein CTD PMID:31266599 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
decreases expression
EXP [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA
bisphenol A results in decreased expression of GPX1 mRNA
CTD PMID:28819136 PMID:29129240 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GYS1 glycogen synthase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter CTD PMID:29065941 NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
JBrowse link
G HMOX1 heme oxygenase 1 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of HMOX1 mRNA
Cysteine inhibits the reaction [bisphenol A results in decreased expression of HMOX1 mRNA]
CTD PMID:37999554
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions
decreases expression
EXP bisphenol A promotes the reaction [fisetin results in decreased expression of HSD3B1 mRNA]; fisetin promotes the reaction [bisphenol A results in decreased expression of HSD3B1 mRNA] CTD PMID:29544186 NCBI chr 4:101,565,229...101,574,110 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
EXP bisphenol A results in increased expression of HSPA5 mRNA; bisphenol A results in increased expression of HSPA5 protein
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of HSPA5 mRNA]
CTD PMID:37108405 PMID:38845341 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
G IFNG interferon gamma increases expression
multiple interactions
EXP bisphenol A results in increased expression of IFNG mRNA
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IFNG mRNA]
CTD PMID:37108405 PMID:38154151 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
JBrowse link
G IGF1 insulin like growth factor 1 decreases expression EXP bisphenol A results in decreased expression of IGF1 mRNA CTD PMID:32710935 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G IGF1R insulin like growth factor 1 receptor decreases expression EXP bisphenol A results in decreased expression of IGF1R mRNA CTD PMID:32710935 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
JBrowse link
G IL10 interleukin 10 multiple interactions
decreases expression
decreases secretion
EXP Glutamine inhibits the reaction [bisphenol A results in decreased secretion of IL10 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of IL10 mRNA] CTD PMID:37108405 PMID:38154151 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G IL17A interleukin 17A increases expression
multiple interactions
EXP bisphenol A results in increased expression of IL17A mRNA
Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL17A mRNA]
CTD PMID:37108405 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
JBrowse link
G IL6 interleukin 6 multiple interactions
increases secretion
increases expression
EXP Glutamine inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA]; Glutamine inhibits the reaction [bisphenol A results in increased secretion of IL6 protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA] CTD PMID:37108405 PMID:38154151 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G KEAP1 kelch like ECH associated protein 1 increases expression
multiple interactions
EXP bisphenol A results in increased expression of KEAP1 mRNA
Cysteine inhibits the reaction [bisphenol A results in increased expression of KEAP1 mRNA]
CTD PMID:37999554 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
JBrowse link
G LDHA lactate dehydrogenase A increases expression
multiple interactions
decreases methylation
EXP bisphenol A results in increased expression of LDHA mRNA
[bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter
bisphenol A results in decreased methylation of LDHA promoter
CTD PMID:29065941 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
JBrowse link
G LOC100623720 collagen alpha-1(VI) chain multiple interactions
decreases expression
EXP bisphenol A inhibits the reaction [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased expression of COL6A1 protein]
bisphenol A results in decreased expression of COL6A1 protein
CTD PMID:31266599 NCBI chr13:208,295,245...208,321,789
Ensembl chr13:208,295,451...208,313,127
JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression
multiple interactions
increases secretion
EXP bisphenol A results in increased expression of IL1B mRNA; bisphenol A results in increased expression of IL1B protein
Glutamine inhibits the reaction [bisphenol A results in increased secretion of IL1B protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL1B mRNA]
CTD PMID:29558425 PMID:37108405 PMID:38154151
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression EXP bisphenol A results in increased expression of MAP1LC3B protein CTD PMID:31266599 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 affects expression EXP bisphenol A affects the expression of MAP3K7 protein CTD PMID:29577965 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor increases expression
multiple interactions
EXP bisphenol A results in increased expression of MYD88 mRNA
Glutamine inhibits the reaction [bisphenol A results in increased expression of MYD88 mRNA]
CTD PMID:38154151 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109
JBrowse link
G NANOG Nanog homeobox decreases expression EXP bisphenol A results in decreased expression of NANOG mRNA CTD PMID:28819136 NCBI chr 5:62,931,642...62,939,086
Ensembl chr 5:62,932,382...62,939,082
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
EXP bisphenol A results in increased expression of NFKB1 mRNA
Glutamine inhibits the reaction [bisphenol A results in increased expression of NFKB1 mRNA]
CTD PMID:38154151 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
JBrowse link
G NOS1 nitric oxide synthase 1 increases expression EXP bisphenol A results in increased expression of NOS1 protein CTD PMID:38069115 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944
JBrowse link
G NOX1 NADPH oxidase 1 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of NOX1 mRNA
Cysteine inhibits the reaction [bisphenol A results in decreased expression of NOX1 mRNA]
CTD PMID:37999554 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,667...82,586,532
JBrowse link
G OCLN occludin decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of OCLN protein
Sodium Selenite affects the reaction [bisphenol A results in decreased expression of OCLN protein]
CTD PMID:37108405 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
JBrowse link
G PLIN1 perilipin 1 increases expression
multiple interactions
EXP bisphenol A results in increased expression of PLIN1 protein
[bisphenol A co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] results in increased expression of PLIN1 protein
CTD PMID:31266599 NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797
JBrowse link
G POU5F1 POU class 5 homeobox 1 decreases expression EXP bisphenol A results in decreased expression of POU5F1 mRNA; bisphenol A results in decreased expression of POU5F1 protein CTD PMID:28819136 NCBI chr 7:23,564,654...23,570,691 JBrowse link
G PPP1R16A protein phosphatase 1 regulatory subunit 16A increases activity
multiple interactions
EXP bisphenol A results in increased activity of GPT protein
Cysteine inhibits the reaction [bisphenol A results in increased activity of GPT protein]
CTD PMID:37999554 NCBI chr 4:302,621...320,048
Ensembl chr 4:297,748...320,056
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases expression EXP bisphenol A results in decreased expression of PTGS1 mRNA CTD PMID:38845341 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
EXP ursodoxicoltaurine inhibits the reaction [bisphenol A results in decreased expression of PTGS2 mRNA] CTD PMID:38845341 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G PTX3 pentraxin 3 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of PTX3 mRNA
ursodoxicoltaurine inhibits the reaction [bisphenol A results in decreased expression of PTX3 mRNA]
CTD PMID:38845341 NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP bisphenol A results in increased expression of RELA protein
Glutamine inhibits the reaction [bisphenol A results in increased expression of RELA protein]
CTD PMID:38154151 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of SDHA mRNA
Cysteine inhibits the reaction [bisphenol A results in decreased expression of SDHA mRNA]
CTD PMID:37999554 NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
JBrowse link
G SI sucrase-isomaltase decreases expression EXP bisphenol A results in decreased expression of SI mRNA CTD PMID:28445388 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
JBrowse link
G SLC15A1 solute carrier family 15 member 1 decreases expression
decreases methylation
multiple interactions
EXP bisphenol A results in decreased expression of SLC15A1 mRNA
bisphenol A results in decreased methylation of SLC15A1 promoter
[Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]
CTD PMID:28445388 NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
JBrowse link
G SLC18A3 solute carrier family 18 member A3 decreases expression EXP bisphenol A results in decreased expression of SLC18A3 protein CTD PMID:29558425 PMID:29577965 NCBI chr14:90,113,534...90,115,813
Ensembl chr14:90,113,844...90,115,430
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA CTD PMID:28445388 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
JBrowse link
G SLC7A1 solute carrier family 7 member 1 increases expression EXP bisphenol A results in increased expression of SLC7A1 mRNA CTD PMID:32710935 NCBI chr11:6,538,053...6,604,654
Ensembl chr11:6,538,045...6,604,658
JBrowse link
G SLC7A7 solute carrier family 7 member 7 decreases expression EXP bisphenol A results in decreased expression of SLC7A7 mRNA CTD PMID:32710935 NCBI chr 7:76,195,774...76,235,406
Ensembl chr 7:76,198,256...76,235,402
JBrowse link
G SOD1 superoxide dismutase 1 decreases expression EXP bisphenol A results in decreased expression of SOD1 mRNA CTD PMID:29129240 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link
G SOD2 superoxide dismutase 2 decreases expression
multiple interactions
EXP bisphenol A results in decreased expression of SOD2 mRNA
Cysteine inhibits the reaction [bisphenol A results in decreased expression of SOD2 mRNA]
CTD PMID:37999554 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G SOX2 SRY-box transcription factor 2 decreases expression EXP bisphenol A results in decreased expression of SOX2 mRNA CTD PMID:28819136 NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP [bisphenol A co-treated with fisetin] results in decreased expression of STAR mRNA; fisetin promotes the reaction [bisphenol A results in decreased expression of STAR mRNA] CTD PMID:29544186 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462
JBrowse link
G TAC1 tachykinin precursor 1 increases expression EXP bisphenol A results in increased expression of TAC1 protein CTD PMID:29558425 PMID:29569701 PMID:29888781 PMID:38069115 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523
JBrowse link
G TFAM transcription factor A, mitochondrial decreases expression EXP bisphenol A results in decreased expression of TFAM mRNA CTD PMID:28819136 NCBI chr14:92,261,713...92,279,731
Ensembl chr14:92,259,403...92,279,731
JBrowse link
G TFF3 trefoil factor 3 multiple interactions
decreases expression
EXP Glutamine inhibits the reaction [bisphenol A results in decreased expression of TFF3 protein] CTD PMID:38154151 NCBI chr13:205,641,038...205,644,333
Ensembl chr13:205,641,038...205,644,333
JBrowse link
G TJP1 tight junction protein 1 multiple interactions
decreases expression
EXP Sodium Selenite affects the reaction [bisphenol A results in decreased expression of TJP1 protein] CTD PMID:37108405 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
JBrowse link
G TJP2 tight junction protein 2 multiple interactions
decreases expression
EXP Cysteine inhibits the reaction [bisphenol A results in decreased expression of TJP2 mRNA] CTD PMID:37999554 NCBI chr 1:222,474,518...222,612,989
Ensembl chr 1:222,474,639...222,612,983
JBrowse link
G TLR4 toll like receptor 4 multiple interactions
increases expression
EXP Glutamine inhibits the reaction [bisphenol A results in increased expression of TLR4 mRNA]; Glutamine inhibits the reaction [bisphenol A results in increased expression of TLR4 protein]
bisphenol A results in increased expression of TLR4 mRNA; bisphenol A results in increased expression of TLR4 protein
CTD PMID:38154151 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
JBrowse link
G TNF tumor necrosis factor increases expression
increases secretion
multiple interactions
EXP bisphenol A results in increased expression of TNF mRNA; bisphenol A results in increased expression of TNF protein
bisphenol A results in increased secretion of TNF protein
Glutamine inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]; Glutamine inhibits the reaction [bisphenol A results in increased secretion of TNF protein]; Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]
CTD PMID:29558425 PMID:37108405 PMID:38154151 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
JBrowse link
G TP53 tumor protein p53 increases expression EXP bisphenol A results in increased expression of TP53 protein CTD PMID:28819136 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP bisphenol A results in increased expression of VEGFA protein CTD PMID:20172683 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
JBrowse link
G VIP vasoactive intestinal peptide decreases expression
increases expression
EXP bisphenol A results in decreased expression of VIP protein
bisphenol A results in increased expression of VIP protein
CTD PMID:29558425 PMID:29577965 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269
JBrowse link
G XPO5 exportin 5 multiple interactions
decreases expression
EXP [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of XPO5 mRNA; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with bisphenol A] results in decreased expression of XPO5 protein
bisphenol A results in decreased expression of XPO5 mRNA; bisphenol A results in decreased expression of XPO5 protein
CTD PMID:31266599 NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,531,919...38,569,582
JBrowse link
bisphenol F term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP 4,4'-bisphenol F inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone] CTD PMID:34019995 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G MMP9 matrix metallopeptidase 9 increases expression EXP 4,4'-bisphenol F results in increased expression of MMP9 mRNA CTD PMID:34019995 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
JBrowse link
calcidiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 increases hydroxylation EXP CYP2D6 protein results in increased hydroxylation of Calcifediol CTD PMID:11880238 NCBI chr 5:6,539,021...6,543,643
Ensembl chr 5:6,538,907...6,543,642
JBrowse link
carbon monoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions EXP CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] CTD PMID:21984542 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP [HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide; chromium mesoporphyrin inhibits the reaction [[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide]; tin protoporphyrin IX inhibits the reaction [[HMOX1 protein results in increased metabolism of Heme] which results in increased abundance of Carbon Monoxide] CTD PMID:16751286
G NFKBIA NFKB inhibitor alpha multiple interactions EXP NFKBIA protein inhibits the reaction [Carbon Monoxide results in decreased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP NFKBIA protein inhibits the reaction [Carbon Monoxide results in decreased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
JBrowse link
G XDH xanthine dehydrogenase multiple interactions EXP [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide; CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide] CTD PMID:21984542 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169
JBrowse link
choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein CTD PMID:29129240 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA CTD PMID:28445388 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA CTD PMID:28445388 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA CTD PMID:29129240 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GYS1 glycogen synthase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter CTD PMID:29065941 NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter CTD PMID:29065941 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
JBrowse link
G MTHFR methylenetetrahydrofolate reductase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA CTD PMID:28445388 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
JBrowse link
G SI sucrase-isomaltase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA CTD PMID:28445388 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
JBrowse link
G SLC15A1 solute carrier family 15 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA CTD PMID:28445388 NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA CTD PMID:28445388 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA CTD PMID:29129240 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link
cortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions
increases secretion
EXP D-Ala(2),MePhe(4),Met(0)-ol-enkephalin promotes the reaction [AGT protein results in increased secretion of Hydrocortisone] CTD PMID:22100847 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
JBrowse link
G POMC proopiomelanocortin multiple interactions
increases abundance
increases secretion
EXP Ditiocarb promotes the reaction [Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]]; Sodium Selenite inhibits the reaction [POMC protein results in increased secretion of Hydrocortisone]
POMC protein alternative form results in increased abundance of Hydrocortisone
CTD PMID:1666317 PMID:21466817 PMID:22100847 NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
JBrowse link
cysteamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FMO1 flavin containing dimethylaniline monoxygenase 1 increases metabolic processing EXP FMO1 protein results in increased metabolism of Cysteamine CTD PMID:6439199 NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076
JBrowse link
daidzein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 increases expression EXP daidzein results in increased expression of ESR1 mRNA CTD PMID:19617652 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G ESR2 estrogen receptor 2 increases expression EXP daidzein results in increased expression of ESR2 mRNA; daidzein results in increased expression of ESR2 protein CTD PMID:19617652 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565
JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions EXP daidzein inhibits the reaction [LHB protein results in increased abundance of Progesterone] CTD PMID:19617652 NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
JBrowse link
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions EXP daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
JBrowse link
dexamethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA CTD PMID:30481989 NCBI chr 6:79,589,695...79,649,646
Ensembl chr 6:79,589,045...79,649,644
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BCL2L1 mRNA CTD PMID:30481989 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Troglitazone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CASP3 mRNA CTD PMID:30481989 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha increases expression
multiple interactions
EXP Dexamethasone results in increased expression of CEBPA mRNA
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA]
CTD PMID:11225715 PMID:30481989 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA CTD PMID:30481989 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] CTD PMID:30481989 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 increases expression EXP Dexamethasone results in increased expression of CYP17A1 CTD PMID:19852296 NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression EXP Dexamethasone results in increased expression of CYP1A2 mRNA CTD PMID:24176340 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100
JBrowse link
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 increases expression EXP Dexamethasone results in increased expression of CYP3A29 mRNA CTD PMID:24176340 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
JBrowse link
G FABP4 fatty acid binding protein 4 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] CTD PMID:30481989 NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA] CTD PMID:30481989 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA] CTD PMID:30481989 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
JBrowse link
G IRS1 insulin receptor substrate 1 decreases expression EXP Dexamethasone results in decreased expression of IRS1 mRNA CTD PMID:19852296 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,307,284
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
multiple interactions
EXP Dexamethasone results in increased expression of PPARG
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]
CTD PMID:19852296 PMID:30481989 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA CTD PMID:30481989 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687
JBrowse link
G SLC2A4 solute carrier family 2 member 4 decreases expression EXP Dexamethasone results in decreased expression of SLC2A4 mRNA; Dexamethasone results in decreased expression of SLC2A4 protein CTD PMID:19852296 NCBI chr12:52,628,746...52,634,965
Ensembl chr12:52,628,450...52,634,967
JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] CTD PMID:30481989 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
dihydroouabain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 decreases cleavage EXP dihydroouabain results in decreased cleavage of CASP3 protein CTD PMID:28438630 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
dimercaprol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin multiple interactions EXP Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]] CTD PMID:1928324 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
dobutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HK2 hexokinase 2 decreases expression EXP Dobutamine results in decreased expression of HK2 protein CTD PMID:19944370 NCBI chr 3:68,155,656...68,231,187
Ensembl chr 3:68,153,835...68,231,615
JBrowse link
G NOS2 nitric oxide synthase 2 affects response to substance EXP NOS2 protein affects the susceptibility to Dobutamine CTD PMID:20141602 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G PYGM glycogen phosphorylase, muscle associated decreases expression EXP Dobutamine results in decreased expression of PYGM protein CTD PMID:19944370 NCBI chr 2:7,409,330...7,421,256
Ensembl chr 2:7,409,116...7,421,254
JBrowse link
estrone 3-sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1A2 solute carrier organic anion transporter family member 1A2 increases uptake
multiple interactions
EXP SLCO1A2 protein results in increased uptake of estrone sulfate
Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; cefquinome inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Penicillins inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]
CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
JBrowse link
folic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein CTD PMID:29129240 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CBS cystathionine beta-synthase multiple interactions
increases activity
EXP [Ethanol co-treated with Folic Acid deficiency] results in increased activity of CBS protein
Folic Acid deficiency results in increased activity of CBS protein
CTD PMID:16792574 NCBI chr13:206,205,942...206,231,363
Ensembl chr13:206,205,946...206,230,248
JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions EXP [Folic Acid co-treated with Glycine] results in decreased expression of CSF2 mRNA CTD PMID:14662146 NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155
JBrowse link
G CTH cystathionine gamma-lyase multiple interactions EXP [Ethanol co-treated with Folic Acid deficiency] results in increased activity of CTH protein CTD PMID:16792574 NCBI chr 6:142,454,922...142,486,352
Ensembl chr 6:142,454,914...142,486,367
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA CTD PMID:28445388 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA CTD PMID:28445388 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions EXP [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GCLC protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GCLC mRNA CTD PMID:16792574 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA CTD PMID:29129240 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
increases activity
increases expression
EXP [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSR protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSR mRNA
Folic Acid deficiency results in increased activity of GSR protein
Folic Acid deficiency results in increased expression of GSR mRNA
CTD PMID:16792574 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
JBrowse link
G GSS glutathione synthetase multiple interactions EXP [Ethanol co-treated with Folic Acid deficiency] results in increased activity of GSS protein; [Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSS mRNA CTD PMID:16792574 NCBI chr17:38,316,199...38,342,253
Ensembl chr17:38,312,720...38,342,298
JBrowse link
G GYS1 glycogen synthase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter CTD PMID:29065941 NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter CTD PMID:29065941 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
JBrowse link
G LOC106504562 glutathione S-transferase alpha M14 increases expression
multiple interactions
EXP Folic Acid deficiency results in increased expression of GSTA1 mRNA
[Ethanol co-treated with Folic Acid deficiency] results in increased expression of GSTA1 mRNA
CTD PMID:16792574 NCBI chr 7:46,553,813...46,567,596 JBrowse link
G MTHFR methylenetetrahydrofolate reductase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA CTD PMID:28445388 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Folic Acid co-treated with Glycine] results in decreased expression of PTGS1 CTD PMID:14662146 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Folic Acid co-treated with Glycine] results in increased expression of PTGS2 CTD PMID:14662146 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G SI sucrase-isomaltase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA CTD PMID:28445388 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
JBrowse link
G SLC15A1 solute carrier family 15 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA CTD PMID:28445388 NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA CTD PMID:28445388 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
JBrowse link
G SOD1 superoxide dismutase 1 decreases activity
multiple interactions
EXP Folic Acid deficiency results in decreased activity of SOD1 protein
[Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA; [Ethanol co-treated with Folic Acid deficiency] results in decreased activity of SOD1 protein
CTD PMID:16792574 PMID:29129240 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases activity
EXP [Ethanol co-treated with Folic Acid deficiency] results in increased activity of SOD2 protein
Folic Acid deficiency results in increased activity of SOD2 protein; Folic Acid results in increased activity of SOD2 protein
CTD PMID:16792574 PMID:22889112 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
gabapentin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects binding EXP Gabapentin binds to CACNA2D1 protein CTD PMID:11687876 NCBI chr 9:97,781,057...98,265,925
Ensembl chr 9:97,781,090...98,266,969
JBrowse link
genistein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 decreases expression EXP Genistein results in decreased expression of ESR1 protein CTD PMID:22443950 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [TNF protein results in increased expression of HIF1A protein] CTD PMID:11514583 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
JBrowse link
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions EXP Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Chlortetracycline]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Penicillins]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP Genistein inhibits the reaction [TNF protein results in increased expression of HIF1A protein] CTD PMID:11514583 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
JBrowse link
glutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of AOC1 protein] CTD PMID:36615853 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974
JBrowse link
G CYP2B6B cytochrome P450 family 2 subfamily B member 6B multiple interactions EXP [Glutathione co-treated with Paraquat] results in decreased expression of CYP2B6B mRNA CTD PMID:36615853 NCBI chr 6:49,158,175...49,173,872
Ensembl chr 6:49,110,812...49,178,334
JBrowse link
G CYP3A39 cytochrome P450 3A39 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of CYP3A39 mRNA] CTD PMID:36615853
G DNAJC7 DnaJ heat shock protein family (Hsp40) member C7 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of DNAJC7 mRNA CTD PMID:36615853 NCBI chr12:20,725,937...20,756,295
Ensembl chr12:20,725,975...20,759,000
JBrowse link
G FABP2 fatty acid binding protein 2 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased activity of FABP2 protein] CTD PMID:36615853 NCBI chr 8:104,464,342...104,468,059
Ensembl chr 8:104,464,342...104,470,480
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of GCLM mRNA CTD PMID:36615853 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G GPX4 glutathione peroxidase 4 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of GPX4 mRNA CTD PMID:36615853 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Glutathione co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA CTD PMID:36615853
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions EXP Glutathione inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Glutathione inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] CTD PMID:16785314 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
JBrowse link
G IFNG interferon gamma multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of IFNG mRNA] CTD PMID:36615853 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
JBrowse link
G IL10 interleukin 10 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of IL10 mRNA CTD PMID:36615853 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G LOC100739508 glutathione S-transferase P-like multiple interactions EXP GSTP1 protein affects the metabolism of [monobromobimane co-treated with Glutathione] CTD PMID:14573868 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G LOC106504562 glutathione S-transferase alpha M14 multiple interactions EXP [Glutathione co-treated with Paraquat] results in increased expression of GSTA2 mRNA; Glutathione inhibits the reaction [Paraquat results in decreased expression of GSTA1 mRNA] CTD PMID:36615853 NCBI chr 7:46,553,813...46,567,596 JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in increased expression of NR1I3 mRNA] CTD PMID:36615853 NCBI chr 4:89,226,314...89,231,781
Ensembl chr 4:89,226,690...89,236,431
JBrowse link
G OCLN occludin multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in decreased expression of OCLN protein] CTD PMID:36615853 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP [Glutathione co-treated with Paraquat] affects the expression of SOD2 mRNA CTD PMID:36615853 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G TJP1 tight junction protein 1 multiple interactions EXP Glutathione inhibits the reaction [Paraquat results in decreased expression of TJP1 protein] CTD PMID:36615853 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
JBrowse link
glycine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in increased expression of AIFM1 mRNA] CTD PMID:35839969 NCBI chr  X:106,676,596...106,708,290
Ensembl chr  X:106,670,520...106,708,317
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in increased expression of BAX mRNA] CTD PMID:35839969 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G CASP3 caspase 3 multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in increased expression of and results in increased activity of CASP3 protein]; Glycine inhibits the reaction [monobutyl phthalate results in increased expression of CASP3 mRNA] CTD PMID:35839969 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CAT catalase multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CAT mRNA] CTD PMID:35839969 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CDC26 cell division cycle 26 multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CDC26 mRNA] CTD PMID:35839969 NCBI chr 1:253,893,666...253,906,659
Ensembl chr 1:253,895,885...253,906,632
JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions EXP [Folic Acid co-treated with Glycine] results in decreased expression of CSF2 mRNA CTD PMID:14662146 NCBI chr 2:134,354,724...134,357,155
Ensembl chr 2:134,354,724...134,357,155
JBrowse link
G MFN1 mitofusin 1 multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 protein] CTD PMID:35839969 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
JBrowse link
G MFN2 mitofusin 2 multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN2 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN2 protein] CTD PMID:35839969 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Folic Acid co-treated with Glycine] results in decreased expression of PTGS1 CTD PMID:14662146 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Folic Acid co-treated with Glycine] results in increased expression of PTGS2 CTD PMID:14662146 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G TUBA1B tubulin alpha 1b multiple interactions EXP Glycine inhibits the reaction [monobutyl phthalate results in increased expression of TUBA1B mRNA] CTD PMID:35839969 NCBI chr 5:15,150,229...15,153,620
Ensembl chr 5:15,149,099...15,153,620
JBrowse link
glycine betaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein] CTD PMID:36584959 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
JBrowse link
G ATF6 activating transcription factor 6 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of ATF6 mRNA] CTD PMID:36584959 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA CTD PMID:36584959 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G CASP3 caspase 3 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of CASP3 mRNA] CTD PMID:36584959 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP9 caspase 9 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA] CTD PMID:36584959 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G CAT catalase multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] promotes the reaction [bisphenol A results in decreased expression of CAT protein]; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT mRNA; [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of CAT protein; Betaine inhibits the reaction [Glyphosate results in increased expression of CAT mRNA] CTD PMID:29129240 PMID:36584959 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CLDN1 claudin 1 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein] CTD PMID:36584959 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA] CTD PMID:36584959 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT1 mRNA CTD PMID:28445388 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of DNMT3A mRNA CTD PMID:28445388 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 protein] CTD PMID:36584959 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 protein] CTD PMID:36584959 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of ERN1 mRNA] CTD PMID:36584959 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of GPX1 mRNA; [bisphenol A co-treated with [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12]] results in increased expression of GPX1 mRNA CTD PMID:29129240 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions EXP [Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA CTD PMID:36584959 NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
JBrowse link
G GYS1 glycogen synthase 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Folic Acid co-treated with bisphenol A] results in increased methylation of GYS1 promoter; [Betaine co-treated with Choline co-treated with Folic Acid] results in decreased expression of GYS1 mRNA; [Betaine co-treated with Choline co-treated with Folic Acid] results in increased methylation of GYS1 promoter CTD PMID:29065941 NCBI chr 6:54,234,600...54,250,211
Ensembl chr 6:54,233,050...54,250,261
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 protein] CTD PMID:36584959 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP [bisphenol A co-treated with Choline co-treated with Folic Acid co-treated with Betaine] results in decreased methylation of LDHA promoter CTD PMID:29065941 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
JBrowse link
G MFN1 mitofusin 1 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA] CTD PMID:36584959 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
JBrowse link
G MTHFR methylenetetrahydrofolate reductase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of MTHFR mRNA CTD PMID:28445388 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of NFE2L2 mRNA] CTD PMID:36584959 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA] CTD PMID:36584959 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA protein] CTD PMID:36584959 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA] CTD PMID:36584959 NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
JBrowse link
G SI sucrase-isomaltase multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SI mRNA CTD PMID:28445388 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
JBrowse link
G SLC15A1 solute carrier family 15 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased expression of SLC15A1 mRNA]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] inhibits the reaction [bisphenol A results in decreased methylation of SLC15A1 promoter]; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC15A1 mRNA CTD PMID:28445388 NCBI chr11:67,652,808...67,690,457
Ensembl chr11:67,652,193...67,710,933
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with bisphenol A] results in increased expression of SLC5A1 mRNA; [Betaine co-treated with Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SLC5A1 mRNA CTD PMID:28445388 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions EXP [Betaine co-treated with Folic Acid co-treated with Choline co-treated with Vitamin B 12] results in increased expression of SOD1 mRNA CTD PMID:29129240 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of SOD2 mRNA] CTD PMID:36584959 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G UQCRB ubiquinol-cytochrome c reductase binding protein multiple interactions EXP [Betaine co-treated with Glyphosate] results in decreased expression of UQCRB mRNA CTD PMID:36584959 NCBI chr 4:40,403,272...40,409,080
Ensembl chr 4:40,403,109...40,409,057
JBrowse link
G XBP1 X-box binding protein 1 multiple interactions EXP Betaine inhibits the reaction [Glyphosate results in increased expression of XBP1 mRNA] CTD PMID:36584959 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
JBrowse link
glyphosate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 increases expression
multiple interactions
EXP Glyphosate results in increased expression of ATF4 mRNA; Glyphosate results in increased expression of ATF4 protein
Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of ATF4 protein]
CTD PMID:36584959 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
JBrowse link
G ATF6 activating transcription factor 6 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of ATF6 mRNA] CTD PMID:36584959 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP [Betaine co-treated with Glyphosate] results in increased expression of BAX mRNA
Glyphosate results in increased expression of BAX mRNA
CTD PMID:36584959 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of CASP3 mRNA] CTD PMID:36584959 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of CASP9 mRNA] CTD PMID:36584959 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G CAT catalase increases expression
multiple interactions
increases activity
EXP Glyphosate results in increased expression of CAT mRNA
Betaine inhibits the reaction [Glyphosate results in increased expression of CAT mRNA]
Glyphosate results in increased activity of CAT protein
CTD PMID:31677563 PMID:36584959 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CLDN1 claudin 1 multiple interactions
decreases expression
EXP Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 mRNA]; Betaine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein]
Glyphosate results in decreased expression of CLDN1 mRNA; Glyphosate results in decreased expression of CLDN1 protein
CTD PMID:31677563 PMID:36584959 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions
EXP Glyphosate results in increased expression of CXCL8 mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [Glyphosate results in increased expression of CXCL8 mRNA]
CTD PMID:35388968 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of DDIT3 mRNA] CTD PMID:36584959 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2AK3 protein]
Glyphosate results in increased expression of EIF2AK3 mRNA; Glyphosate results in increased expression of EIF2AK3 protein
CTD PMID:36584959 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of EIF2S1 protein]
Glyphosate results in increased expression of EIF2S1 mRNA; Glyphosate results in increased expression of EIF2S1 protein
CTD PMID:36584959 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions
EXP Glyphosate results in increased expression of ERN1 mRNA
Betaine inhibits the reaction [Glyphosate results in increased expression of ERN1 mRNA]
CTD PMID:36584959 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit decreases expression EXP Glyphosate results in decreased expression of GCLM mRNA CTD PMID:31677563 PMID:35388968 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression
decreases activity
EXP Glyphosate results in decreased expression of GPX1 mRNA
Glyphosate results in decreased activity of GPX1 protein
CTD PMID:31677563 PMID:35388968 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions EXP [Betaine co-treated with Glyphosate] results in increased expression of GPX2 mRNA CTD PMID:36584959 NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
JBrowse link
G GSTO1 glutathione S-transferase omega 1 increases expression EXP Glyphosate results in increased expression of GSTO1 mRNA CTD PMID:36584959 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613
JBrowse link
G HMOX1 heme oxygenase 1 decreases expression
multiple interactions
increases expression
EXP Glyphosate results in decreased expression of HMOX1 mRNA
Glyphosate results in increased expression of and affects the localization of HMOX1 protein
Glyphosate results in increased expression of HMOX1 mRNA
CTD PMID:31677563 PMID:35388968 PMID:36584959
G HSP90B1 heat shock protein 90 beta family member 1 increases expression
multiple interactions
EXP Glyphosate results in increased expression of HSP90B1 mRNA; Glyphosate results in increased expression of HSP90B1 protein
Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of HSP90B1 protein]
CTD PMID:36584959 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
JBrowse link
G IL10 interleukin 10 increases expression EXP Glyphosate results in increased expression of IL10 protein CTD PMID:36584959 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
affects secretion
EXP Glyphosate results in increased expression of IL6 mRNA; Glyphosate results in increased expression of IL6 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Glyphosate results in increased expression of IL6 mRNA]
Glyphosate affects the secretion of IL6 protein
CTD PMID:31677563 PMID:35388968 PMID:36584959 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G KEAP1 kelch like ECH associated protein 1 decreases expression EXP Glyphosate results in decreased expression of KEAP1 mRNA CTD PMID:35388968 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression
multiple interactions
increases secretion
EXP Glyphosate results in increased expression of IL1B mRNA; Glyphosate results in increased expression of IL1B protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Glyphosate results in increased expression of IL1B mRNA]
Glyphosate results in increased secretion of IL1B protein
CTD PMID:35388968 PMID:36584959
G MFN1 mitofusin 1 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of MFN1 mRNA] CTD PMID:36584959 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of NFE2L2 mRNA]; Glyphosate results in increased expression of and affects the localization of NFE2L2 protein
Glyphosate results in increased expression of NFE2L2 mRNA; Glyphosate results in increased expression of NFE2L2 protein
CTD PMID:31677563 PMID:35388968 PMID:36584959 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases expression EXP Glyphosate results in increased expression of NFKB1 mRNA CTD PMID:31677563 PMID:35388968 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP Glyphosate results in decreased expression of and results in increased phosphorylation of NFKBIA protein CTD PMID:35388968 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression EXP Glyphosate results in increased expression of NOS2 mRNA CTD PMID:35388968 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP Glyphosate results in increased expression of NQO1 mRNA
Betaine inhibits the reaction [Glyphosate results in increased expression of NQO1 mRNA]
CTD PMID:31677563 PMID:35388968 PMID:36584959 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
JBrowse link
G PCNA proliferating cell nuclear antigen increases expression
multiple interactions
EXP Glyphosate results in increased expression of PCNA mRNA; Glyphosate results in increased expression of PCNA protein
Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA mRNA]; Betaine inhibits the reaction [Glyphosate results in increased expression of PCNA protein]
CTD PMID:36584959 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases phosphorylation EXP Glyphosate results in increased phosphorylation of RELA protein CTD PMID:35388968 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of SDHA mRNA] CTD PMID:36584959 NCBI chr16:79,838,442...79,862,956
Ensembl chr16:79,834,044...79,862,524
JBrowse link
G SOD1 superoxide dismutase 1 decreases activity EXP Glyphosate results in decreased activity of SOD1 protein CTD PMID:35388968 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
JBrowse link
G SOD2 superoxide dismutase 2 increases expression
multiple interactions
EXP Glyphosate results in increased expression of SOD2 mRNA
Betaine inhibits the reaction [Glyphosate results in increased expression of SOD2 mRNA]
CTD PMID:36584959 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G SQSTM1 sequestosome 1 decreases expression
multiple interactions
EXP Glyphosate results in decreased expression of SQSTM1 protein
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of SQSTM1 protein]
CTD PMID:35388968 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
JBrowse link
G TJP1 tight junction protein 1 decreases expression EXP Glyphosate results in decreased expression of TJP1 mRNA CTD PMID:31677563 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
JBrowse link
G TNF tumor necrosis factor affects secretion
increases expression
EXP Glyphosate affects the secretion of TNF protein
Glyphosate results in increased expression of TNF protein
CTD PMID:35388968 PMID:36584959 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
JBrowse link
G UQCRB ubiquinol-cytochrome c reductase binding protein multiple interactions EXP [Betaine co-treated with Glyphosate] results in decreased expression of UQCRB mRNA CTD PMID:36584959 NCBI chr 4:40,403,272...40,409,080
Ensembl chr 4:40,403,109...40,409,057
JBrowse link
G XBP1 X-box binding protein 1 multiple interactions
increases expression
EXP Betaine inhibits the reaction [Glyphosate results in increased expression of XBP1 mRNA] CTD PMID:36584959 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
JBrowse link
histamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HRH2 histamine receptor H2 multiple interactions EXP [Histamine affects the activity of HRH2 protein] which affects the secretion of Chlorides CTD PMID:12665126 NCBI chr 2:81,883,670...81,932,464
Ensembl chr 2:81,883,673...81,932,275
JBrowse link
L-1,4-dithiothreitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 multiple interactions EXP Dithiothreitol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] CTD PMID:21296058 NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Dithiothreitol metabolite results in increased expression of HSPA5 protein CTD PMID:17416481 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions EXP Dithiothreitol inhibits the reaction [Cadmium Chloride results in decreased activity of IDH2 protein]; Dithiothreitol inhibits the reaction [Cadmium results in decreased activity of IDH2 protein] CTD PMID:16785314 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
JBrowse link
melatonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] CTD PMID:37120089
G ARB2A ARB2 cotranscriptional regulator A multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ARB2A mRNA] CTD PMID:37120089 NCBI chr 2:100,477,770...100,893,594
Ensembl chr 2:100,477,775...100,893,580
JBrowse link
G ATG5 autophagy related 5 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in increased expression of ATG5 protein] CTD PMID:37120089 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of BAX protein] CTD PMID:35665993 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression
EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Melatonin inhibits the reaction [Malathion results in decreased expression of BCL2 mRNA]
Melatonin results in increased expression of BCL2 mRNA
CTD PMID:31535366 PMID:37120089 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BECN1 beclin 1 increases expression
multiple interactions
EXP Melatonin results in increased expression of BECN1 protein
Melatonin inhibits the reaction [deoxynivalenol results in increased expression of BECN1 protein]
CTD PMID:37120089 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G CASP3 caspase 3 decreases expression
multiple interactions
EXP Melatonin results in decreased expression of CASP3 mRNA
Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP3 protein]
CTD PMID:31535366 PMID:35665993 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CASP8 caspase 8 multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in decreased expression of CASP8 protein] CTD PMID:35665993 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CASP9 caspase 9 multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of CASP9 protein] CTD PMID:35665993 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
JBrowse link
G CAT catalase multiple interactions
increases activity
EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Malathion results in decreased expression of CAT mRNA]
Melatonin results in increased activity of CAT protein
CTD PMID:31535366 PMID:37120089 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CHUK mRNA] CTD PMID:37120089 NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868
JBrowse link
G CLDN1 claudin 1 multiple interactions
increases expression
EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]
Melatonin results in increased expression of CLDN1 protein
CTD PMID:37120089 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G COX7A2L cytochrome c oxidase subunit 7A2 like multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of COX7A2L mRNA] CTD PMID:35665993 NCBI chr 3:97,951,115...97,983,309
Ensembl chr 3:97,951,114...97,983,309
JBrowse link
G GPX4 glutathione peroxidase 4 increases expression EXP Melatonin results in increased expression of GPX4 mRNA CTD PMID:31535366 NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
JBrowse link
G IL18 interleukin 18 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA] CTD PMID:37120089 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
JBrowse link
G IL6 interleukin 6 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein] CTD PMID:37120089 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G KLF5 KLF transcription factor 5 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of KLF5 mRNA] CTD PMID:37120089 NCBI chr11:45,370,009...45,386,673
Ensembl chr11:45,369,810...45,388,314
JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein] CTD PMID:37120089
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions EXP Melatonin affects the reaction [deoxynivalenol results in increased expression of and results in increased lipidation of MAP1LC3B protein] CTD PMID:37120089 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of MAP2K1 mRNA] CTD PMID:37120089 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226
JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of MLKL protein] CTD PMID:35665993 NCBI chr 6:12,923,846...12,951,176
Ensembl chr 6:12,924,894...12,951,173
JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein]
Melatonin results in decreased phosphorylation of MTOR protein
CTD PMID:37120089 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G OCLN occludin multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] CTD PMID:37120089 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
JBrowse link
G PLIN2 perilipin 2 multiple interactions EXP Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 protein] CTD PMID:31535366 NCBI chr 1:203,683,867...203,709,277
Ensembl chr 1:203,683,862...203,709,273
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG protein] CTD PMID:31535366 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of PTEN protein] CTD PMID:35665993 NCBI chr14:99,929,590...100,021,619 JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK1 protein] CTD PMID:35665993 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699
JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 multiple interactions EXP Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 mRNA]; Melatonin inhibits the reaction [tetrabromobisphenol A results in increased expression of RIPK3 protein] CTD PMID:35665993 NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251
JBrowse link
G SOD2 superoxide dismutase 2 increases expression
multiple interactions
EXP Melatonin results in increased expression of SOD2 mRNA
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of SOD2 mRNA]
CTD PMID:31535366 PMID:37120089 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G TJP1 tight junction protein 1 increases expression
multiple interactions
EXP Melatonin results in increased expression of TJP1 protein
Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein]
CTD PMID:37120089 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in increased expression of TNF protein] CTD PMID:37120089 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
JBrowse link
G TP53 tumor protein p53 multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Malathion results in increased expression of TP53 mRNA]
Melatonin results in decreased expression of TP53 mRNA
CTD PMID:31535366 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 multiple interactions EXP Melatonin inhibits the reaction [deoxynivalenol results in decreased expression of ZFP36L2 mRNA] CTD PMID:37120089 NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,407...97,204,698
JBrowse link
mercaptoethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 multiple interactions EXP Mercaptoethanol inhibits the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] CTD PMID:21296058 NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
JBrowse link
N(5)-ethyl-L-glutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] CTD PMID:38438008 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 mRNA] CTD PMID:38438008 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G CASP3 caspase 3 multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA] CTD PMID:38438008 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CLDN1 claudin 1 multiple interactions EXP [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN1 protein]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of CLDN1 mRNA] CTD PMID:37271275 PMID:38438008 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G IL6 interleukin 6 multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 mRNA] CTD PMID:38438008 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G LDHA lactate dehydrogenase A multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in increased activity of LDHA protein] CTD PMID:38438008 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,814,169...40,826,715
JBrowse link
G LOC110258578 interleukin-1 beta-like multiple interactions EXP [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL1B mRNA]; theanine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:37271275 PMID:38438008
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK14 protein]; theanine inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA] CTD PMID:37271275 PMID:38438008 NCBI chr 7:31,791,398...31,861,544
Ensembl chr 7:31,790,877...31,862,031
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; theanine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA] CTD PMID:37271275 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228
JBrowse link
G OCLN occludin multiple interactions EXP [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; [SB 203580 co-treated with theanine] inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of OCLN protein]; theanine inhibits the reaction [Lipopolysaccharides results in decreased expression of OCLN mRNA] CTD PMID:37271275 PMID:38438008 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RELA protein] CTD PMID:38438008 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
JBrowse link
G TJP1 tight junction protein 1 multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 mRNA]; theanine inhibits the reaction [Hydrogen Peroxide results in decreased expression of TJP1 protein] CTD PMID:38438008 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP theanine inhibits the reaction [Hydrogen Peroxide results in increased expression of TNF mRNA] CTD PMID:38438008 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415
JBrowse link
nitric oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 multiple interactions EXP ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] CTD PMID:12672649 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703
JBrowse link
G AGT angiotensinogen affects activity EXP Nitric Oxide affects the activity of AGT protein CTD PMID:21127344 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP Nitric Oxide results in increased phosphorylation of and results in decreased activity of BCL2 protein CTD PMID:16039061 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G CAPN1 calpain 1 decreases expression EXP Nitric Oxide results in decreased expression of CAPN1 mRNA CTD PMID:9728040 NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,985...7,022,684
JBrowse link
G EDN1 endothelin 1 increases abundance
multiple interactions
EXP EDN1 protein results in increased abundance of Nitric Oxide
Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein]
CTD PMID:12672649 PMID:17105827 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
JBrowse link
G KNG1 kininogen 1 multiple interactions
increases abundance
EXP ACE protein inhibits the reaction [KNG1 protein results in increased abundance of Nitric Oxide] CTD PMID:12672649 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,340...124,557,958
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP Resveratrol inhibits the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide] CTD PMID:20825639 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
decreases activity
EXP TXNRD1 protein inhibits the reaction [Nitric Oxide results in decreased activity of NOS3 protein] CTD PMID:8810647 PMID:10823391 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
JBrowse link
G TAC1 tachykinin precursor 1 increases abundance EXP TAC1 protein results in increased abundance of Nitric Oxide CTD PMID:12672649 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523
JBrowse link
G TXNRD1 thioredoxin reductase 1 multiple interactions EXP TXNRD1 protein inhibits the reaction [Nitric Oxide results in decreased activity of NOS3 protein] CTD PMID:8810647 NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,172,260...80,236,219
JBrowse link
notoginsenoside R1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 decreases expression EXP notoginsenoside R1 results in decreased expression of IL10 protein CTD PMID:25721049 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G IL4 interleukin 4 decreases expression EXP notoginsenoside R1 results in decreased expression of IL4 protein CTD PMID:25721049 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
ouabain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 decreases activity EXP Ouabain results in decreased activity of ATP1A1 protein CTD PMID:28438630 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680
JBrowse link
G CASP3 caspase 3 decreases cleavage EXP Ouabain results in decreased cleavage of CASP3 protein CTD PMID:28438630 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
oxytocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide multiple interactions
increases secretion
EXP STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Oxytocin] CTD PMID:19528263 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917
JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions
increases secretion
EXP STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Oxytocin]
STAT1 protein results in increased secretion of Oxytocin
CTD PMID:19528263 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
JBrowse link
phosphatidylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB4 ATP binding cassette subfamily B member 4 increases export
multiple interactions
EXP ABCB4 protein results in increased export of Phosphatidylcholines
Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]
CTD PMID:21056966 NCBI chr 9:93,171,371...93,262,124 JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 increases hydrolysis EXP PDIA3 protein results in increased hydrolysis of Phosphatidylcholines CTD PMID:16798117 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
JBrowse link
progesterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen increases secretion EXP AGT protein results in increased secretion of Progesterone CTD PMID:22100847 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 affects expression EXP Progesterone affects the expression of CRABP1 protein CTD PMID:11833939 NCBI chr 7:47,602,316...47,608,865
Ensembl chr 7:47,602,192...47,608,970
JBrowse link
G CST3 cystatin C affects expression EXP Progesterone affects the expression of CST3 mRNA CTD PMID:20107207 NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590
JBrowse link
G CTSB cathepsin B increases expression EXP Progesterone results in increased expression of CTSB mRNA CTD PMID:20107207 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877
JBrowse link
G CTSL cathepsin L increases expression EXP Progesterone results in increased expression of CTSL mRNA CTD PMID:20107207 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618
JBrowse link
G EGFR epidermal growth factor receptor affects chemical synthesis EXP EGFR protein affects the chemical synthesis of Progesterone CTD PMID:21520325 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G FGF2 fibroblast growth factor 2 multiple interactions EXP Progesterone inhibits the reaction [estrone benzoate results in decreased expression of FGF2 mRNA] CTD PMID:15120423 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 multiple interactions
decreases expression
EXP estrone benzoate inhibits the reaction [Progesterone results in decreased expression of FGFR1 mRNA alternative form] CTD PMID:15120423 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 decreases expression
multiple interactions
EXP Progesterone results in decreased expression of FGFR2 mRNA alternative form
[Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of FGFR2 mRNA alternative form
CTD PMID:15120423 PMID:15976484 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
JBrowse link
G FSHB follicle stimulating hormone subunit beta increases chemical synthesis
increases abundance
multiple interactions
EXP FSHB protein results in increased chemical synthesis of Progesterone
FSHB protein results in increased abundance of Progesterone
4,4'-bisphenol F inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; [FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone; [FSHB protein co-treated with Lead co-treated with Mercury] results in decreased secretion of Progesterone; bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; bisphenol A promotes the reaction [fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; bisphenol S inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; fisetin inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]; fisetin promotes the reaction [bisphenol A inhibits the reaction [FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone]]; FSHB protein results in increased chemical synthesis of and results in increased secretion of Progesterone; Lapatinib inhibits the reaction [FSHB protein results in increased abundance of Progesterone]; Zearalenone promotes the reaction [FSHB protein results in increased abundance of Progesterone]
CTD PMID:17656051 PMID:20390873 PMID:20965553 PMID:23375200 PMID:29544186 More... NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G GHRL ghrelin and obestatin prepropeptide multiple interactions
decreases secretion
increases secretion
EXP Aminoglutethimide promotes the reaction [GHRL protein results in decreased secretion of Progesterone]; GHRL protein results in decreased chemical synthesis of and results in decreased secretion of Progesterone; STAT1 protein inhibits the reaction [GHRL protein results in decreased secretion of Progesterone]
GHRL protein results in increased secretion of Progesterone
CTD PMID:17904772 PMID:19528263 PMID:22341706 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917
JBrowse link
G HOXA10 homeobox A10 increases expression
multiple interactions
EXP Progesterone results in increased expression of HOXA10 mRNA
Estradiol promotes the reaction [Progesterone results in increased expression of HOXA10 mRNA]
CTD PMID:21705055 NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions
increases abundance
EXP [FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone; deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased abundance of Progesterone]; Zearalenone promotes the reaction [IGF1 protein results in increased abundance of Progesterone] CTD PMID:17656051 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G LEP leptin multiple interactions
increases expression
increases secretion
EXP [TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone
Progesterone results in increased expression of LEP mRNA
Progesterone results in increased secretion of LEP protein
CTD PMID:22151798 PMID:23153703 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323
JBrowse link
G LHB luteinizing hormone subunit beta increases abundance
multiple interactions
EXP LHB protein results in increased abundance of Progesterone
daidzein inhibits the reaction [LHB protein results in increased abundance of Progesterone]; Lapatinib inhibits the reaction [LHB protein results in increased abundance of Progesterone]
CTD PMID:19617652 PMID:23375200 NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions EXP Progesterone affects the reaction [OXT protein results in increased abundance of Calcium]; Progesterone inhibits the reaction [OXT protein results in increased abundance of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprostone]; Progesterone inhibits the reaction [OXT protein results in increased transport of Calcium] CTD PMID:16997130 PMID:21370738 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546
JBrowse link
G PLAU plasminogen activator, urokinase increases expression EXP Progesterone results in increased expression of PLAU mRNA CTD PMID:23103014 NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172
JBrowse link
G POMC proopiomelanocortin increases secretion EXP POMC protein results in increased secretion of Progesterone CTD PMID:22100847 NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418
JBrowse link
G RBP4 retinol binding protein 4 affects expression EXP Progesterone affects the expression of RBP4 protein CTD PMID:11833939 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765
JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP STAT1 protein inhibits the reaction [GHRL protein results in decreased secretion of Progesterone] CTD PMID:19528263 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260
JBrowse link
G TP53 tumor protein p53 multiple interactions
decreases secretion
EXP [TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone
TP53 protein results in decreased secretion of Progesterone
CTD PMID:22151798 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
quercetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl affects the localization of and results in increased activity of AHR protein] CTD PMID:12970578 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] CTD PMID:25087994 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147
JBrowse link
G CAV1 caveolin 1 multiple interactions EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of and results in increased phosphorylation of CAV1 protein] CTD PMID:19608276 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
decreases activity
EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]
Quercetin results in decreased activity of CYP1A1 protein
CTD PMID:12970578 PMID:19608276 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
JBrowse link
G IL6 interleukin 6 multiple interactions EXP Quercetin inhibits the reaction [Linoleic Acid results in increased expression of IL6 mRNA] CTD PMID:15051824 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP Quercetin promotes the reaction [[Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein] CTD PMID:25087994 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] CTD PMID:21375526 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 multiple interactions EXP Quercetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PECAM1 protein] CTD PMID:21375526 NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,649,044...14,723,293
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP Quercetin inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein] CTD PMID:15051824 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
JBrowse link
G SELE selectin E multiple interactions EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELE mRNA] CTD PMID:19608276 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G SELP selectin P multiple interactions EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of SELP mRNA] CTD PMID:19608276 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955
JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Quercetin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:19605544 NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP Quercetin inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA] CTD PMID:15051824 PMID:19608276 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222
JBrowse link
rutin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Rutin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:19605544 NCBI chr 1:7,289,278...7,323,418
Ensembl chr 1:7,289,831...7,323,146
JBrowse link
S-nitrosoglutathione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] CTD PMID:11514583
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP 2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; AKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Genistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]; Wortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] CTD PMID:11514583 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP PIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] CTD PMID:11514583 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609
JBrowse link
serotonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP Serotonin results in increased expression of FOS mRNA; Serotonin results in increased expression of FOS protein
sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein]
CTD PMID:11426759 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN mRNA]; sarpogrelate inhibits the reaction [Serotonin results in increased expression of JUN protein]
Serotonin results in increased expression of JUN mRNA; Serotonin results in increased expression of JUN protein
CTD PMID:11426759 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
EXP Serotonin results in increased phosphorylation of MAPK1 protein
sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK1 protein]
CTD PMID:11426759 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
EXP sarpogrelate inhibits the reaction [Serotonin results in increased phosphorylation of MAPK3 protein] CTD PMID:11426759 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
testosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing multiple interactions
increases secretion
EXP 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; bisphenol A inhibits the reaction [ADIPOQ protein results in increased secretion of Testosterone]; halowax 1051 promotes the reaction [ADIPOQ protein results in increased secretion of Testosterone]; Testosterone results in decreased expression of and results in decreased secretion of ADIPOQ protein CTD PMID:28284726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646
JBrowse link
G ADIPOR1 adiponectin receptor 1 decreases expression EXP Testosterone results in decreased expression of ADIPOR1 protein CTD PMID:28284726 NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686
JBrowse link
G ADIPOR2 adiponectin receptor 2 decreases expression EXP Testosterone results in decreased expression of ADIPOR2 protein CTD PMID:28284726 NCBI chr 5:68,755,789...68,807,247
Ensembl chr 5:68,755,811...68,807,235
JBrowse link
G CYP19A3 cytochrome P450 19A3 multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein CTD PMID:16151981 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 multiple interactions
increases hydroxylation
EXP Ketoconazole inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone] CTD PMID:20863320 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944
JBrowse link
G INS insulin multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; [LHB protein co-treated with INS protein] results in increased abundance of Testosterone; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone] CTD PMID:11889176 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G LHB luteinizing hormone subunit beta increases secretion
multiple interactions
EXP LHB protein results in increased secretion of Testosterone
9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; [LHB protein co-treated with INS protein] results in increased abundance of Testosterone; Biological Products inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Cod Liver Oil inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Industrial Waste inhibits the reaction [LHB protein results in increased secretion of Testosterone]; Troglitazone inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]
CTD PMID:11889176 PMID:26055946 NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086
JBrowse link
zearalenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 decreases expression EXP Zearalenone results in decreased expression of ABCC9 mRNA CTD PMID:34933075 NCBI chr 5:51,536,531...51,673,583
Ensembl chr 5:51,536,526...51,691,595
JBrowse link
G ABCF1 ATP binding cassette subfamily F member 1 increases expression EXP Zearalenone results in increased expression of ABCF1 mRNA CTD PMID:25455459 NCBI chr 7:23,126,255...23,144,030
Ensembl chr 7:23,126,283...23,143,994
JBrowse link
G ABLIM2 actin binding LIM protein family member 2 decreases expression EXP Zearalenone results in decreased expression of ABLIM2 mRNA CTD PMID:34933075 NCBI chr 8:2,948,948...3,054,974
Ensembl chr 8:2,916,775...3,054,966
JBrowse link
G ACE2 angiotensin converting enzyme 2 decreases expression EXP Zearalenone results in decreased expression of ACE2 mRNA CTD PMID:34933075 NCBI chr  X:12,099,849...12,152,204
Ensembl chr  X:12,093,242...12,151,286
JBrowse link
G ADAM22 ADAM metallopeptidase domain 22 decreases expression EXP Zearalenone results in decreased expression of ADAM22 mRNA CTD PMID:34933075 NCBI chr 9:68,253,023...68,490,327
Ensembl chr 9:68,253,065...68,487,619
JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 decreases expression EXP Zearalenone results in decreased expression of ADAM33 mRNA CTD PMID:34933075 NCBI chr17:32,023,102...32,038,464
Ensembl chr17:32,023,091...32,037,880
JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 decreases expression EXP Zearalenone results in decreased expression of ADAMTS18 mRNA CTD PMID:34933075 NCBI chr 6:10,488,504...10,652,508
Ensembl chr 6:10,488,374...10,652,504
JBrowse link
G ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 increases expression EXP Zearalenone results in increased expression of ADAMTS20 mRNA CTD PMID:34933075 NCBI chr 5:74,502,098...74,672,703
Ensembl chr 5:74,503,113...74,672,703
JBrowse link
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 decreases expression EXP Zearalenone results in decreased expression of ADAMTS3 mRNA CTD PMID:34933075 NCBI chr 8:68,675,067...68,948,537
Ensembl chr 8:68,675,070...68,948,414
JBrowse link
G ADAMTSL1 ADAMTS like 1 decreases expression EXP Zearalenone results in decreased expression of ADAMTSL1 mRNA CTD PMID:34933075 NCBI chr 1:203,936,654...204,944,236
Ensembl chr 1:203,936,657...204,942,412
JBrowse link
G ADCY5 adenylate cyclase 5 decreases expression EXP Zearalenone results in decreased expression of ADCY5 mRNA CTD PMID:34933075 NCBI chr13:136,965,746...137,133,795
Ensembl chr13:136,972,801...137,135,347
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I decreases expression EXP Zearalenone results in decreased expression of ADCYAP1R1 mRNA CTD PMID:34933075 NCBI chr18:41,915,180...41,972,327
Ensembl chr18:41,917,428...41,972,301
JBrowse link
G ADGRE5 adhesion G protein-coupled receptor E5 increases expression EXP Zearalenone results in increased expression of ADGRE5 mRNA CTD PMID:25455459 NCBI chr 2:64,844,793...64,862,231
Ensembl chr 2:64,844,798...64,890,939
JBrowse link
G ADRA2A adrenoceptor alpha 2A decreases expression EXP Zearalenone results in decreased expression of ADRA2A mRNA CTD PMID:34933075 NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924
JBrowse link
G AIFM2 apoptosis inducing factor mitochondria associated 2 increases expression EXP Zearalenone results in increased expression of AIFM2 mRNA CTD PMID:25455459 NCBI chr14:73,054,433...73,074,605
Ensembl chr14:73,055,228...73,074,567
JBrowse link
G AKR1C1 aldo-keto reductase family 1, member C1 decreases expression EXP Zearalenone results in decreased expression of AKR1C1 mRNA CTD PMID:34933075 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248
JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 decreases expression EXP Zearalenone results in decreased expression of ALDH1A3 mRNA CTD PMID:34933075 NCBI chr 1:139,451,080...139,491,514
Ensembl chr 1:139,451,049...139,491,511
JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 decreases expression EXP Zearalenone results in decreased expression of ALDH3A1 mRNA CTD PMID:34933075 NCBI chr12:59,895,476...59,905,900
Ensembl chr12:59,897,496...59,905,897
JBrowse link
G ANGPT4 angiopoietin 4 decreases expression EXP Zearalenone results in decreased expression of ANGPT4 mRNA CTD PMID:34933075 NCBI chr17:34,345,926...34,394,977
Ensembl chr17:34,348,556...34,402,851
JBrowse link
G ANXA8 annexin A8 increases expression EXP Zearalenone results in increased expression of ANXA8 mRNA CTD PMID:34933075 NCBI chr14:88,319,209...88,340,716 JBrowse link
G APAF1 apoptotic peptidase activating factor 1 decreases expression EXP Zearalenone results in decreased expression of APAF1 mRNA CTD PMID:34933075 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364
JBrowse link
G ARHGAP20 Rho GTPase activating protein 20 decreases expression EXP Zearalenone results in decreased expression of ARHGAP20 mRNA CTD PMID:34933075 NCBI chr 9:38,471,049...38,582,221
Ensembl chr 9:38,474,865...38,582,242
JBrowse link
G ASPN asporin decreases expression EXP Zearalenone results in decreased expression of ASPN mRNA CTD PMID:34933075 NCBI chr 3:42,165,553...42,192,902
Ensembl chr 3:42,165,561...42,192,813
JBrowse link
G ASTN1 astrotactin 1 decreases expression EXP Zearalenone results in decreased expression of ASTN1 mRNA CTD PMID:34933075 NCBI chr 9:118,649,144...118,969,032
Ensembl chr 9:118,646,910...118,968,970
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression EXP Zearalenone results in decreased expression of ATP1A2 mRNA CTD PMID:34933075 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,341,322...90,370,996
JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 decreases expression EXP Zearalenone results in decreased expression of AUTS2 mRNA CTD PMID:34933075 NCBI chr 3:13,565,439...14,794,365
Ensembl chr 3:13,565,281...14,794,365
JBrowse link
G AVPR1A vasopressin receptor 1A decreases expression EXP Zearalenone results in decreased expression of AVPR1A mRNA CTD PMID:34933075 NCBI chr 5:27,824,991...27,832,794
Ensembl chr 5:27,824,992...27,832,703
JBrowse link
G BAALC BAALC binder of MAP3K1 and KLF4 increases expression EXP Zearalenone results in increased expression of BAALC mRNA CTD PMID:34933075 NCBI chr 4:33,894,240...33,983,920
Ensembl chr 4:33,892,079...33,984,121
JBrowse link
G BAIAP3 BAI1 associated protein 3 decreases expression EXP Zearalenone results in decreased expression of BAIAP3 mRNA CTD PMID:34933075 NCBI chr 3:40,536,557...40,550,508
Ensembl chr 3:40,537,399...40,550,471
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
EXP Zearalenone results in decreased expression of BCL2 mRNA
[Acetylcysteine co-treated with Zearalenone co-treated with deoxynivalenol] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of BCL2 protein; [Acetylcysteine co-treated with Zearalenone] results in increased expression of BCL2 protein; [fumonisin B1 co-treated with Zearalenone co-treated with deoxynivalenol] results in decreased expression of BCL2 protein; [fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]]; fumonisin B1 inhibits the reaction [Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Zearalenone inhibits the reaction [fumonisin B1 inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]]; Zearalenone inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in decreased expression of BCL2 mRNA]]
CTD PMID:29109043 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BMP15 bone morphogenetic protein 15 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [Zearalenone results in decreased expression of BMP15 mRNA] CTD PMID:26386189 NCBI chr  X:44,613,122...44,620,575
Ensembl chr  X:44,613,122...44,620,575
JBrowse link
G BMP2 bone morphogenetic protein 2 affects expression EXP Zearalenone affects the expression of BMP2 mRNA CTD PMID:34933075 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195
JBrowse link
G BOK BCL2 family apoptosis regulator BOK increases expression EXP Zearalenone results in increased expression of BOK mRNA CTD PMID:34933075 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121
JBrowse link
G BPIFC BPI fold containing family C decreases expression EXP Zearalenone results in decreased expression of BPIFC mRNA CTD PMID:34933075 NCBI chr 5:12,526,928...12,578,958
Ensembl chr 5:12,525,806...12,578,954
JBrowse link
G C3 complement C3 decreases expression EXP Zearalenone results in decreased expression of C3 mRNA CTD PMID:34933075 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,212...72,472,228
JBrowse link
G C3H16orf89 chromosome 3 C16orf89 homolog increases expression EXP Zearalenone results in increased expression of C3H16ORF89 mRNA CTD PMID:34933075 NCBI chr 3:37,346,530...37,365,367
Ensembl chr 3:37,346,532...37,365,357
JBrowse link
G C4A complement C4A (Rodgers blood group) decreases expression EXP Zearalenone results in decreased expression of C4A mRNA CTD PMID:34933075 NCBI chr 7:24,068,019...24,083,060
Ensembl chr 7:24,068,013...24,083,065
JBrowse link
G C4BPA complement component 4 binding protein alpha decreases expression EXP Zearalenone results in decreased expression of C4BPA mRNA CTD PMID:34933075 NCBI chr 9:67,726,159...67,774,369
Ensembl chr 9:67,731,179...67,776,115
JBrowse link
G CA11 carbonic anhydrase 11 decreases expression EXP Zearalenone results in decreased expression of CA11 mRNA CTD PMID:34933075 NCBI chr 6:53,993,183...53,999,357
Ensembl chr 6:53,993,394...53,999,172
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E decreases expression EXP Zearalenone results in decreased expression of CACNA1E mRNA CTD PMID:34933075 NCBI chr 9:122,827,386...123,318,372
Ensembl chr 9:123,006,195...123,315,319
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G decreases expression EXP Zearalenone results in decreased expression of CACNA1G mRNA CTD PMID:34933075 NCBI chr12:26,838,633...26,912,344
Ensembl chr12:26,844,079...26,912,110
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H decreases expression EXP Zearalenone results in decreased expression of CACNA1H mRNA CTD PMID:34933075 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,427...40,695,177
JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase increases expression
multiple interactions
EXP Zearalenone results in increased expression of CASP1 mRNA; Zearalenone results in increased expression of CASP1 protein
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 mRNA]
CTD PMID:30270565 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
EXP [Acetylcysteine co-treated with Zearalenone] results in decreased expression of CASP3 protein; [fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]; [fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA; [fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein]]; deoxynivalenol promotes the reaction [[fumonisin B1 co-treated with Zearalenone] results in increased expression of CASP3 mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CASP3 mRNA]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]]; Zearalenone promotes the reaction [[fumonisin B1 co-treated with deoxynivalenol] results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 protein] CTD PMID:29109043 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
JBrowse link
G CAT catalase increases expression EXP Zearalenone results in increased expression of CAT mRNA CTD PMID:23727178 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CCDC158 coiled-coil domain containing 158 decreases expression EXP Zearalenone results in decreased expression of CCDC158 mRNA CTD PMID:34933075 NCBI chr 8:71,990,113...72,088,966
Ensembl chr 8:71,990,119...72,088,829
JBrowse link
G CCKBR cholecystokinin B receptor increases expression EXP Zearalenone results in increased expression of CCKBR mRNA CTD PMID:34933075 NCBI chr 9:3,409,222...3,419,513 JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 multiple interactions
increases expression
EXP [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of CCL2 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CCL2 mRNA
Zearalenone results in increased expression of CCL2 mRNA; Zearalenone results in increased expression of CCL2 protein
CTD PMID:23688591 PMID:29758222 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
JBrowse link
G CCL20 C-C motif chemokine ligand 20 increases expression EXP Zearalenone results in increased expression of CCL20 mRNA CTD PMID:25455459 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCL21 C-C motif chemokine ligand 21 increases expression EXP Zearalenone results in increased expression of CCL21 mRNA CTD PMID:34933075 NCBI chr10:32,093,783...32,094,482
Ensembl chr10:32,093,763...32,096,224
JBrowse link
G CCNB1 cyclin B1 decreases expression EXP Zearalenone results in decreased expression of CCNB1 mRNA; Zearalenone results in decreased expression of CCNB1 protein CTD PMID:29758222 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
JBrowse link
G CD209 CD209 molecule decreases expression EXP Zearalenone results in decreased expression of CD209 mRNA CTD PMID:34933075 NCBI chr 2:71,394,414...71,397,711
Ensembl chr 2:71,394,391...71,397,968
JBrowse link
G CD244 CD244 molecule increases expression EXP Zearalenone results in increased expression of CD244 mRNA CTD PMID:34933075 NCBI chr 4:89,668,221...89,700,974
Ensembl chr 4:89,668,239...89,700,972
JBrowse link
G CDH17 cadherin 17 affects expression EXP Zearalenone affects the expression of CDH17 mRNA CTD PMID:34933075 NCBI chr 4:42,508,852...42,597,888
Ensembl chr 4:42,515,276...42,597,772
JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression EXP Zearalenone results in decreased expression of CDK1 mRNA; Zearalenone results in decreased expression of CDK1 protein CTD PMID:29758222 NCBI chr14:64,233,945...64,255,290
Ensembl chr14:64,233,987...64,372,197
JBrowse link
G CDRT4 CMT1A duplicated region transcript 4 decreases expression EXP Zearalenone results in decreased expression of CDRT4 mRNA CTD PMID:34933075 NCBI chr12:58,816,336...58,881,611 JBrowse link
G CFP complement factor properdin decreases expression EXP Zearalenone results in decreased expression of ELK1 mRNA; Zearalenone results in decreased expression of ELK1 protein CTD PMID:32439583 NCBI chr  X:42,157,980...42,174,964
Ensembl chr  X:42,157,988...42,174,951
JBrowse link
G CHP2 calcineurin like EF-hand protein 2 decreases expression EXP Zearalenone results in decreased expression of CHP2 mRNA CTD PMID:34933075 NCBI chr 3:22,473,241...22,478,697
Ensembl chr 3:22,473,247...22,478,588
JBrowse link
G CLDN1 claudin 1 decreases expression EXP Zearalenone results in decreased expression of CLDN1 protein CTD PMID:32783910 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G CLEC4G C-type lectin domain family 4 member G decreases expression EXP Zearalenone results in decreased expression of CLEC4G mRNA CTD PMID:34933075 NCBI chr 2:71,433,406...71,436,570
Ensembl chr 2:71,433,421...71,436,567
JBrowse link
G CLIC3 chloride intracellular channel 3 increases expression EXP Zearalenone results in increased expression of CLIC3 mRNA CTD PMID:34933075
G CMKLR2 chemerin chemokine-like receptor 2 decreases expression EXP Zearalenone results in decreased expression of CMKLR2 mRNA CTD PMID:34933075 NCBI chr15:109,467,078...109,528,931
Ensembl chr15:109,467,080...109,521,100
JBrowse link
G CNTN4 contactin 4 decreases expression EXP Zearalenone results in decreased expression of CNTN4 mRNA CTD PMID:34933075 NCBI chr13:58,642,653...59,642,134
Ensembl chr13:58,974,198...59,642,130
JBrowse link
G COLGALT2 collagen beta(1-O)galactosyltransferase 2 decreases expression EXP Zearalenone results in decreased expression of COLGALT2 mRNA CTD PMID:34933075 NCBI chr 9:125,149,806...125,291,092
Ensembl chr 9:125,148,753...125,291,057
JBrowse link
G CPA1 carboxypeptidase A1 increases expression EXP Zearalenone results in increased expression of CPA1 mRNA CTD PMID:34933075 NCBI chr18:18,466,564...18,482,099
Ensembl chr18:18,469,921...18,476,327
JBrowse link
G CPAMD8 C3 and PZP like alpha-2-macroglobulin domain containing 8 decreases expression EXP Zearalenone results in decreased expression of CPAMD8 mRNA CTD PMID:34933075 NCBI chr 2:60,636,025...60,742,120
Ensembl chr 2:60,636,047...60,742,137
JBrowse link
G CPED1 cadherin like and PC-esterase domain containing 1 decreases expression EXP Zearalenone results in decreased expression of CPED1 mRNA CTD PMID:34933075 NCBI chr18:25,655,730...25,937,923
Ensembl chr18:25,655,735...25,937,232
JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 decreases expression EXP Zearalenone results in decreased expression of CXCL13 mRNA CTD PMID:34933075 NCBI chr 8:73,071,261...73,077,342 JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 increases expression EXP Zearalenone results in increased expression of CXCL14 mRNA CTD PMID:34933075 NCBI chr 2:137,803,988...137,813,118
Ensembl chr 2:137,803,992...137,813,118
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
decreases secretion
multiple interactions
EXP Zearalenone results in increased expression of CXCL8 mRNA
Zearalenone results in decreased secretion of CXCL8 protein
[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of CXCL8 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of CXCL8 mRNA
CTD PMID:21763767 PMID:23688591 PMID:34933075 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 increases expression EXP Zearalenone results in increased expression of CXCR2 mRNA; Zearalenone results in increased expression of CXCR2 protein CTD PMID:29758222 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYCS cytochrome c, somatic increases expression
multiple interactions
EXP Zearalenone results in increased expression of CYCS mRNA
[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]]; deoxynivalenol promotes the reaction [[Zearalenone co-treated with fumonisin B1] results in increased expression of CYCS mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol promotes the reaction [Zearalenone results in increased expression of CYCS mRNA]]; Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of CYCS mRNA]
CTD PMID:29109043 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions EXP Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA] CTD PMID:17656051 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478
JBrowse link
G CYP19A3 cytochrome P450 19A3 multiple interactions
decreases expression
EXP Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]
Zearalenone results in decreased expression of CYP19A1 protein
CTD PMID:17656051 PMID:29758222 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G CYP21A1 cytochrome P450 family 21 subfamily A member 1 decreases expression EXP Zearalenone results in decreased expression of CYP21A1 mRNA CTD PMID:34933075 NCBI chr 7:24,086,138...24,089,364
Ensembl chr 7:24,086,218...24,089,370
JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 increases expression EXP Zearalenone results in increased expression of CYP4F22 mRNA CTD PMID:34933075 NCBI chr 2:62,078,403...62,110,891
Ensembl chr 2:62,081,269...62,110,899
JBrowse link
G DDIT4 DNA damage inducible transcript 4 increases expression EXP Zearalenone results in increased expression of DDIT4 mRNA CTD PMID:25455459 NCBI chr14:75,117,708...75,119,907
Ensembl chr14:75,117,710...75,119,902
JBrowse link
G DEFB1 defensin beta 1 increases expression EXP Zearalenone results in increased expression of DEFB1 mRNA CTD PMID:34933075
G DEGS2 delta 4-desaturase, sphingolipid 2 increases expression EXP Zearalenone results in increased expression of DEGS2 mRNA CTD PMID:34933075 NCBI chr 7:121,058,102...121,131,612
Ensembl chr 7:121,058,105...121,076,328
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 decreases expression EXP Zearalenone results in decreased expression of DKK1 mRNA CTD PMID:25455459 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,288
JBrowse link
G DLG2 discs large MAGUK scaffold protein 2 decreases expression EXP Zearalenone results in decreased expression of DLG2 mRNA CTD PMID:34933075 NCBI chr 9:17,575,991...19,547,417
Ensembl chr 9:17,576,135...19,545,916
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 decreases expression EXP Zearalenone results in decreased expression of DLG4 mRNA CTD PMID:34933075 NCBI chr12:52,550,138...52,574,021
Ensembl chr12:52,550,141...52,575,143
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 increases expression EXP Zearalenone results in increased expression of DLK1 mRNA CTD PMID:34933075 NCBI chr 7:121,565,844...121,577,493
Ensembl chr 7:121,565,854...121,576,654
JBrowse link
G DNASE1L2 deoxyribonuclease 1 like 2 decreases expression EXP Zearalenone results in decreased expression of DNASE1L2 mRNA CTD PMID:34933075 NCBI chr 3:39,757,725...39,761,497
Ensembl chr 3:39,757,296...39,761,080
JBrowse link
G DNM1 dynamin 1 decreases expression EXP Zearalenone results in decreased expression of DNM1 mRNA CTD PMID:34933075 NCBI chr 1:268,653,045...268,702,233
Ensembl chr 1:268,653,070...268,702,222
JBrowse link
G DSG3 desmoglein 3 increases expression EXP Zearalenone results in increased expression of DSG3 mRNA CTD PMID:34933075 NCBI chr 6:115,352,005...115,383,750
Ensembl chr 6:115,351,925...115,383,743
JBrowse link
G EBF3 EBF transcription factor 3 increases expression EXP Zearalenone results in increased expression of EBF3 mRNA CTD PMID:25455459 NCBI chr14:138,819,846...138,935,504
Ensembl chr14:138,819,848...138,935,462
JBrowse link
G ELF5 E74 like ETS transcription factor 5 affects expression EXP Zearalenone affects the expression of ELF5 mRNA CTD PMID:34933075 NCBI chr 2:26,443,979...26,486,802
Ensembl chr 2:26,443,977...26,485,903
JBrowse link
G EPYC epiphycan decreases expression EXP Zearalenone results in decreased expression of EPYC mRNA CTD PMID:34933075 NCBI chr 5:91,837,672...91,877,779
Ensembl chr 5:91,832,291...91,877,982
JBrowse link
G ESR1 estrogen receptor 1 increases expression EXP Zearalenone results in increased expression of ESR1 mRNA CTD PMID:22484360 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G EXTL1 exostosin like glycosyltransferase 1 decreases expression EXP Zearalenone results in decreased expression of EXTL1 mRNA CTD PMID:34933075 NCBI chr 6:83,461,421...83,476,601
Ensembl chr 6:83,462,323...83,476,596
JBrowse link
G FAM184B family with sequence similarity 184 member B increases expression EXP Zearalenone results in increased expression of FAM184B mRNA CTD PMID:34933075 NCBI chr 8:12,635,359...12,741,482
Ensembl chr 8:12,634,377...12,741,488
JBrowse link
G FIBCD1 fibrinogen C domain containing 1 increases expression EXP Zearalenone results in increased expression of FIBCD1 mRNA CTD PMID:34933075 NCBI chr 1:270,919,793...270,956,753
Ensembl chr 1:270,918,251...270,956,347
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP Zearalenone results in decreased expression of FMO1 mRNA CTD PMID:25455459 PMID:34933075 NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076
JBrowse link
G FNDC4 fibronectin type III domain containing 4 decreases expression EXP Zearalenone results in decreased expression of FNDC4 mRNA CTD PMID:34933075 NCBI chr 3:111,677,569...111,682,496
Ensembl chr 3:111,678,892...111,682,426
JBrowse link
G FRMPD4 FERM and PDZ domain containing 4 decreases expression EXP Zearalenone results in decreased expression of FRMPD4 mRNA CTD PMID:34933075 NCBI chr  X:8,625,039...9,451,433
Ensembl chr  X:8,542,382...9,438,821
JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions EXP Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]; Zearalenone promotes the reaction [FSHB protein results in increased abundance of Progesterone] CTD PMID:17656051 NCBI chr 2:30,395,769...30,399,282
Ensembl chr 2:30,395,018...30,399,274
JBrowse link
G FST follistatin decreases expression EXP Zearalenone results in decreased expression of FST mRNA CTD PMID:25455459 NCBI chr16:32,806,341...32,811,382
Ensembl chr16:32,805,932...32,811,421
JBrowse link
G GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 affects expression EXP Zearalenone affects the expression of GALNT12 mRNA CTD PMID:34933075 NCBI chr 1:240,595,423...240,639,625
Ensembl chr 1:240,595,394...240,640,563
JBrowse link
G GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 increases expression EXP Zearalenone results in increased expression of GALNT6 mRNA CTD PMID:34933075
G GALR1 galanin receptor 1 decreases expression EXP Zearalenone results in decreased expression of GALR1 mRNA CTD PMID:34933075 NCBI chr 1:147,442,977...147,466,731
Ensembl chr 1:147,443,821...147,463,542
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit affects expression
increases expression
EXP Zearalenone affects the expression of GCLC protein
Zearalenone results in increased expression of GCLC mRNA
CTD PMID:31760079 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit affects expression
increases expression
EXP Zearalenone affects the expression of GCLM mRNA; Zearalenone affects the expression of GCLM protein
Zearalenone results in increased expression of GCLM mRNA
CTD PMID:31760079 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
G GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type decreases expression EXP Zearalenone results in decreased expression of GCNT3 mRNA CTD PMID:34933075 NCBI chr 1:112,424,212...112,540,984
Ensembl chr 1:112,422,879...112,540,983
JBrowse link
G GDF7 growth differentiation factor 7 decreases expression EXP Zearalenone results in decreased expression of GDF7 mRNA CTD PMID:34933075 NCBI chr 3:117,586,188...117,592,541
Ensembl chr 3:117,587,430...117,592,466
JBrowse link
G GDF9 growth differentiation factor 9 decreases expression EXP Zearalenone results in decreased expression of GDF9 mRNA CTD PMID:25455459 NCBI chr 2:135,181,494...135,184,451
Ensembl chr 2:135,181,089...135,187,026
JBrowse link
G GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 decreases expression EXP Zearalenone results in decreased expression of GDPD1 mRNA CTD PMID:34933075 NCBI chr12:35,481,194...35,527,588
Ensembl chr12:35,481,215...35,528,092
JBrowse link
G GJA1 gap junction protein alpha 1 decreases expression EXP Zearalenone results in decreased expression of GJA1 mRNA CTD PMID:26386189 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156
JBrowse link
G GJA4 gap junction protein alpha 4 decreases expression EXP Zearalenone results in decreased expression of GJA4 mRNA CTD PMID:26386189 NCBI chr 6:91,045,430...91,048,161
Ensembl chr 6:91,045,394...91,048,162
JBrowse link
G GLI2 GLI family zinc finger 2 decreases expression EXP Zearalenone results in decreased expression of GLI2 mRNA CTD PMID:34933075 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306
JBrowse link
G GLT6D1 glycosyltransferase 6 domain containing 1 decreases expression EXP Zearalenone results in decreased expression of GLT6D1 mRNA CTD PMID:34933075
G GNAI2 G protein subunit alpha i2 increases expression EXP Zearalenone results in increased expression of GNAI2 mRNA CTD PMID:25455459 NCBI chr13:32,705,326...32,733,804
Ensembl chr13:32,705,321...32,733,794
JBrowse link
G GNAO1 G protein subunit alpha o1 decreases expression EXP Zearalenone results in decreased expression of GNAO1 mRNA CTD PMID:34933075 NCBI chr 6:29,416,574...29,592,874
Ensembl chr 6:29,417,603...29,592,706
JBrowse link
G GPX1 glutathione peroxidase 1 increases expression EXP Zearalenone results in increased expression of GPX1 mRNA; Zearalenone results in increased expression of GPX1 protein CTD PMID:23727178 PMID:31760079 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GPX6 glutathione peroxidase 6 increases expression EXP Zearalenone results in increased expression of GPX6 mRNA CTD PMID:25455459 NCBI chr 7:22,256,013...22,267,992
Ensembl chr 7:22,256,038...22,267,992
JBrowse link
G GRB10 growth factor receptor bound protein 10 decreases expression EXP Zearalenone results in decreased expression of GRB10 mRNA CTD PMID:25455459 NCBI chr 9:136,580,363...136,742,552
Ensembl chr 9:136,580,362...136,741,756
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 decreases expression EXP Zearalenone results in decreased expression of GRID2 mRNA CTD PMID:34933075 NCBI chr 8:125,821,195...127,130,617
Ensembl chr 8:125,819,951...127,129,763
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions EXP Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]]; fumonisin B1 promotes the reaction [Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]]; Zearalenone promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]; Zearalenone promotes the reaction [fumonisin B1 promotes the reaction [deoxynivalenol results in decreased activity of GSR protein]] CTD PMID:29109043 NCBI chr15:54,382,564...54,433,989
Ensembl chr15:54,382,567...54,433,984
JBrowse link
G GTF3C4 general transcription factor IIIC subunit 4 increases expression EXP Zearalenone results in increased expression of GTF3C4 mRNA CTD PMID:25455459 NCBI chr 1:272,454,488...272,479,968
Ensembl chr 1:272,454,503...272,479,965
JBrowse link
G GTSF1 gametocyte specific factor 1 increases expression EXP Zearalenone results in increased expression of GTSF1 mRNA CTD PMID:34933075 NCBI chr 5:19,639,326...19,661,773
Ensembl chr 5:19,645,135...19,661,599
JBrowse link
G HEPH hephaestin increases expression EXP Zearalenone results in increased expression of HEPH mRNA CTD PMID:34933075 NCBI chr  X:52,314,911...52,397,384
Ensembl chr  X:52,314,935...52,397,380
JBrowse link
G HMOX1 heme oxygenase 1 affects expression
decreases expression
multiple interactions
EXP Zearalenone affects the expression of HMOX1 mRNA; Zearalenone affects the expression of HMOX1 protein
Zearalenone results in decreased expression of HMOX1 mRNA; Zearalenone results in decreased expression of HMOX1 protein
[Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]]; [Heterocyclic Compounds results in decreased activity of NFE2L2 protein] inhibits the reaction [Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein]]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 mRNA]; Proanthocyanidins inhibits the reaction [Zearalenone results in decreased expression of HMOX1 protein]
CTD PMID:31760079 PMID:35489465
G HOXA10 homeobox A10 decreases expression EXP Zearalenone results in decreased expression of HOXA10 mRNA CTD PMID:34933075 NCBI chr18:45,393,525...45,403,259
Ensembl chr18:45,393,885...45,403,257
JBrowse link
G IFNG interferon gamma multiple interactions
increases expression
EXP [Zearalenone co-treated with deoxynivalenol] results in decreased expression of IFNG mRNA; Zearalenone results in decreased expression of and results in decreased secretion of IFNG protein; Zearalenone results in increased expression of and results in increased secretion of IFNG protein
Zearalenone results in increased expression of IFNG mRNA
CTD PMID:18296887 PMID:23727178 PMID:34933075 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
JBrowse link
G IGF1 insulin like growth factor 1 decreases expression
multiple interactions
EXP Zearalenone results in decreased expression of IGF1 mRNA; Zearalenone results in decreased expression of IGF1 protein
Zearalenone affects the reaction [IGF1 protein results in increased abundance of Estradiol]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]; Zearalenone promotes the reaction [IGF1 protein results in increased abundance of Progesterone]
CTD PMID:17656051 PMID:29758222 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 decreases expression EXP Zearalenone results in decreased expression of IGFBP5 mRNA CTD PMID:34933075 NCBI chr15:118,861,816...118,877,787
Ensembl chr15:118,857,625...118,878,120
JBrowse link
G IGSF3 immunoglobulin superfamily member 3 decreases expression EXP Zearalenone results in decreased expression of IGSF3 mRNA CTD PMID:34933075 NCBI chr 4:104,044,784...104,167,173
Ensembl chr 4:103,994,390...104,166,988
JBrowse link
G IGSF5 immunoglobulin superfamily member 5 increases expression EXP Zearalenone results in increased expression of IGSF5 mRNA CTD PMID:34933075 NCBI chr13:203,325,385...203,372,361 JBrowse link
G IGSF9B immunoglobulin superfamily member 9B decreases expression EXP Zearalenone results in decreased expression of IGSF9B mRNA CTD PMID:34933075 NCBI chr 9:60,467,321...60,521,463
Ensembl chr 9:60,478,029...60,521,465
JBrowse link
G IL10 interleukin 10 multiple interactions
decreases expression
increases expression
EXP Zearalenone results in decreased expression of and results in decreased secretion of IL10 protein
Zearalenone results in decreased expression of IL10 mRNA
Zearalenone results in increased expression of IL10 protein
CTD PMID:23727178 PMID:34933075 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G IL18 interleukin 18 multiple interactions
increases expression
EXP [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA] CTD PMID:25455459 PMID:30270565 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression
EXP [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA
Zearalenone results in increased expression of IL1A mRNA
CTD PMID:23688591 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121
JBrowse link
G IL2 interleukin 2 multiple interactions
increases expression
EXP [Zearalenone co-treated with deoxynivalenol] results in decreased expression of IL2 mRNA
Zearalenone results in increased expression of IL2 mRNA
CTD PMID:18296887 PMID:34933075 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL22RA1 interleukin 22 receptor subunit alpha 1 increases expression EXP Zearalenone results in increased expression of IL22RA1 mRNA CTD PMID:34933075 NCBI chr 6:81,867,849...81,885,017
Ensembl chr 6:81,867,848...81,884,996
JBrowse link
G IL23R interleukin 23 receptor decreases expression EXP Zearalenone results in decreased expression of IL23R mRNA CTD PMID:34933075 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510
JBrowse link
G IL4 interleukin 4 multiple interactions EXP Zearalenone results in decreased expression of and results in decreased secretion of IL4 protein CTD PMID:23727178 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
EXP Zearalenone results in increased expression of IL6 mRNA; Zearalenone results in increased expression of IL6 protein
[deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone] results in decreased expression of IL6 mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL6 mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL6 mRNA; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of IL6 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]
CTD PMID:23688591 PMID:32783910 PMID:34933075 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G INHBA inhibin subunit beta A increases expression EXP Zearalenone results in increased expression of INHBA mRNA CTD PMID:25455459 NCBI chr12:53,115,379...53,117,128
NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967
JBrowse link
G IP6K3 inositol hexakisphosphate kinase 3 decreases expression EXP Zearalenone results in decreased expression of IP6K3 mRNA CTD PMID:34933075 NCBI chr 7:29,938,779...29,961,520
Ensembl chr 7:29,931,925...29,961,466
JBrowse link
G IRX3 iroquois homeobox 3 increases expression EXP Zearalenone results in increased expression of IRX3 mRNA CTD PMID:34933075 NCBI chr 6:31,044,919...31,049,067
Ensembl chr 6:31,046,146...31,049,054
JBrowse link
G ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 decreases expression EXP Zearalenone results in decreased expression of ISLR2 mRNA CTD PMID:34933075 NCBI chr 7:59,385,021...59,393,185
Ensembl chr 7:59,386,241...59,388,481
JBrowse link
G ITGB5 integrin subunit beta 5 increases expression EXP Zearalenone results in increased expression of ITGB5 mRNA CTD PMID:25455459 NCBI chr13:135,468,111...135,587,483
Ensembl chr13:135,467,798...135,587,473
JBrowse link
G JADE2 jade family PHD finger 2 decreases expression EXP Zearalenone results in decreased expression of JADE2 mRNA CTD PMID:34933075 NCBI chr 2:136,686,056...136,832,004
Ensembl chr 2:136,788,372...136,832,001
JBrowse link
G JAKMIP2 janus kinase and microtubule interacting protein 2 decreases expression EXP Zearalenone results in decreased expression of JAKMIP2 mRNA CTD PMID:34933075 NCBI chr 2:148,864,445...149,045,921
Ensembl chr 2:148,861,751...149,045,927
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 decreases expression EXP Zearalenone results in decreased expression of KCND3 mRNA CTD PMID:34933075 NCBI chr 4:108,394,687...108,621,514
Ensembl chr 4:108,246,237...108,621,510
JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 decreases expression EXP Zearalenone results in decreased expression of KCNK3 mRNA CTD PMID:34933075 NCBI chr 3:112,322,446...112,359,212
Ensembl chr 3:112,322,446...112,359,212
JBrowse link
G KEAP1 kelch like ECH associated protein 1 affects expression
decreases expression
EXP Zearalenone affects the expression of KEAP1 protein
Zearalenone results in decreased expression of KEAP1 mRNA
CTD PMID:31760079 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382
JBrowse link
G KHDRBS3 KH RNA binding domain containing, signal transduction associated 3 decreases expression EXP Zearalenone results in decreased expression of KHDRBS3 mRNA CTD PMID:34933075 NCBI chr 4:6,289,577...6,446,494
Ensembl chr 4:6,282,076...6,446,389
JBrowse link
G KIAA1210 KIAA1210 ortholog decreases expression EXP Zearalenone results in decreased expression of KIAA1210 mRNA CTD PMID:34933075 NCBI chr  X:97,581,400...97,651,765 JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase decreases expression EXP Zearalenone results in decreased expression of KIT mRNA CTD PMID:26386189 NCBI chr 8:41,402,334...41,492,306
Ensembl chr 8:41,402,043...41,493,734
JBrowse link
G KLHDC7A kelch domain containing 7A decreases expression EXP Zearalenone results in decreased expression of KLHDC7A mRNA CTD PMID:34933075 NCBI chr 6:77,022,168...77,030,776
Ensembl chr 6:77,023,865...77,026,255
JBrowse link
G KRT18 keratin 18 increases expression EXP Zearalenone results in increased expression of KRT18 mRNA CTD PMID:34933075 NCBI chr 5:18,217,686...18,221,432
Ensembl chr 5:18,217,691...18,221,429
JBrowse link
G KRT6A keratin 6A increases expression EXP Zearalenone results in increased expression of KRT6A mRNA CTD PMID:34933075 NCBI chr 5:17,830,147...17,851,113
Ensembl chr 5:17,780,928...17,868,402
JBrowse link
G KRT8 keratin 8 increases expression EXP Zearalenone results in increased expression of KRT8 mRNA CTD PMID:34933075 NCBI chr 5:18,172,423...18,180,277
Ensembl chr 5:18,167,553...18,180,404
JBrowse link
G LAMC3 laminin subunit gamma 3 decreases expression EXP Zearalenone results in decreased expression of LAMC3 mRNA CTD PMID:34933075 NCBI chr 1:271,004,423...271,071,223
Ensembl chr 1:271,004,433...271,071,223
JBrowse link
G LGI2 leucine rich repeat LGI family member 2 increases expression EXP Zearalenone results in increased expression of LGI2 mRNA CTD PMID:34933075 NCBI chr 8:18,986,549...19,017,238
Ensembl chr 8:18,986,046...19,017,431
JBrowse link
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 increases expression EXP Zearalenone results in increased expression of LGR5 mRNA CTD PMID:34933075 NCBI chr 5:35,463,257...35,595,234
Ensembl chr 5:35,463,279...35,595,930
JBrowse link
G LOC106504562 glutathione S-transferase alpha M14 decreases expression EXP Zearalenone results in decreased expression of GSTA1 mRNA CTD PMID:34933075 NCBI chr 7:46,553,813...46,567,596 JBrowse link
G LOC110255234 liver carboxylesterase-like increases expression EXP Zearalenone results in increased expression of CES1 mRNA CTD PMID:34933075
G LOC110258578 interleukin-1 beta-like multiple interactions
increases expression
EXP [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; [nivalenol co-treated with Zearalenone] results in increased expression of IL1B mRNA; [Zearalenone co-treated with fumonisin B1] results in increased expression of IL1B mRNA; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of IL1B protein]; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; Zearalenone results in decreased expression of and results in decreased secretion of IL1B protein; Zearalenone results in increased expression of and results in increased secretion of IL1B protein
Zearalenone results in increased expression of IL1B mRNA; Zearalenone results in increased expression of IL1B protein
CTD PMID:23688591 PMID:23727178 PMID:30270565 PMID:32783910 PMID:34933075
G LRFN3 leucine rich repeat and fibronectin type III domain containing 3 decreases expression EXP Zearalenone results in decreased expression of LRFN3 mRNA CTD PMID:34933075 NCBI chr 6:45,343,846...45,352,779
Ensembl chr 6:45,346,637...45,351,990
JBrowse link
G LRFN5 leucine rich repeat and fibronectin type III domain containing 5 decreases expression EXP Zearalenone results in decreased expression of LRFN5 mRNA CTD PMID:34933075 NCBI chr 1:171,906,130...172,177,726
Ensembl chr 1:171,906,198...172,177,720
JBrowse link
G LRRC4B leucine rich repeat containing 4B decreases expression EXP Zearalenone results in decreased expression of LRRC4B mRNA CTD PMID:34933075 NCBI chr 6:55,346,787...55,409,876
Ensembl chr 6:55,346,908...55,409,991
JBrowse link
G LRTM2 leucine rich repeats and transmembrane domains 2 decreases expression EXP Zearalenone results in decreased expression of LRTM2 mRNA CTD PMID:34933075 NCBI chr 5:68,821,815...68,836,518
Ensembl chr 5:68,822,539...68,836,514
JBrowse link
G MAP3K7CL MAP3K7 C-terminal like decreases expression EXP Zearalenone results in decreased expression of MAP3K7CL mRNA CTD PMID:34933075 NCBI chr13:192,488,937...192,534,826
Ensembl chr13:192,489,751...192,534,821
JBrowse link
G MGP matrix Gla protein decreases expression EXP Zearalenone results in decreased expression of MGP mRNA CTD PMID:34933075 NCBI chr 5:57,665,272...57,669,360
Ensembl chr 5:57,665,248...57,669,764
JBrowse link
G MIR331 microRNA mir-331 increases expression EXP Zearalenone results in increased expression of MIR331 mRNA CTD PMID:32439583 NCBI chr 5:88,028,339...88,028,418
Ensembl chr 5:88,028,339...88,028,418
JBrowse link
G MIR744 microRNA mir-744 increases expression EXP Zearalenone results in increased expression of MIR744 mRNA CTD PMID:32439583 NCBI chr12:56,464,848...56,464,927
Ensembl chr12:56,464,848...56,464,927
JBrowse link