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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gamma-tocotrienol
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Accession:CHEBI:33277 term browser browse the term
Definition:A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2. A vitamin E family member that has potent anti-cancer properties against a wide-range of cancers.
Synonyms:exact_synonym: (2R)-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol
 related_synonym: (2R)-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-1-benzopyran-6-ol;   Formula=C28H42O2;   InChI=1S/C28H42O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h11,13,15,19,29H,8-10,12,14,16-18H2,1-7H3/b21-13+,22-15+/t28-/m1/s1;   InChIKey=OTXNTMVVOOBZCV-WAZJVIJMSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1
 alt_id: CHEBI:35082
 xref: Beilstein:43525;   CAS:14101-61-2;   Chemspider:4445514;   FooDB:FDB001298;   HMDB:HMDB0012958;   KEGG:C14155;   KNApSAcK:C00035101;   LIPID_MAPS_instance:LMPR02020057;   MetaCyc:CPD-15838;   PMCID:PMC8308567;   PMID:19195866;   PMID:19557601;   PMID:21429729;   PMID:23341695;   PMID:24959559;   PMID:25423021;   PMID:26930378;   PMID:27128741;   PMID:27356050;   PMID:27864002;   PMID:27869747;   PMID:29283379;   PMID:29642403;   PMID:29787425;   PMID:29957361;   PMID:30070965;   PMID:30183139;   PMID:30497457;   PMID:30845647;   PMID:30866453;   PMID:30901461;   PMID:31414341;   PMID:31877708;   PMID:32283796;   PMID:33343356;   PMID:33847203;   Reaxys:5483919;   Wikipedia:Gamma-Tocotrienol


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gamma-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Gamma-tocotrienol increases phosphorylation of AKT1 protein in PC-3 prostate gland cancer cells RGD PMID:17601486 RGD:408364950 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      chemical role 19467
        antioxidant 16172
          gamma-tocotrienol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            organic molecule 19692
                              organic cyclic compound 19482
                                organic heterocyclic compound 18872
                                  oxacycle 17903
                                    benzopyran 11976
                                      1-benzopyran 11730
                                        chromanes 4026
                                          chromanol 1873
                                            chroman-6-ol 1873
                                              tocol 266
                                                tocotrienol 44
                                                  gamma-tocotrienol 1
paths to the root