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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] |
CTD |
PMID:7564105 |
|
NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
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G |
ATP7B |
ATPase copper transporting beta |
multiple interactions |
EXP |
Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein] |
CTD |
PMID:21084060 |
|
NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
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G |
CALCB |
calcitonin-related polypeptide beta |
increases abundance |
EXP |
CALCA protein results in increased abundance of Cyclic AMP |
CTD |
PMID:18463244 |
|
NCBI chr 2:44,043,135...44,048,651
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G |
DUOX2 |
dual oxidase 2 |
increases expression |
EXP |
Cyclic AMP results in increased expression of DUOX2 mRNA |
CTD |
PMID:10601291 |
|
NCBI chr 1:126,620,468...126,641,406
Ensembl chr 1:126,620,510...126,641,406
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G |
GCG |
glucagon |
affects response to substance increases abundance |
EXP |
Cyclic AMP affects the susceptibility to GCG protein GCG protein results in increased abundance of Cyclic AMP |
CTD |
PMID:6253273 |
|
NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242
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G |
GNRH1 |
gonadotropin releasing hormone 1 |
multiple interactions increases abundance |
EXP |
[Cobalt binds to GNRH1 protein] which results in increased abundance of Cyclic AMP GNRH1 protein results in increased abundance of Cyclic AMP |
CTD |
PMID:15833593 |
|
NCBI chr14:9,442,971...9,447,521
Ensembl chr14:9,442,971...9,453,035
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G |
PDE5A |
phosphodiesterase 5A |
increases degradation |
EXP |
PDE5 protein results in increased degradation of Cyclic GMP |
CTD |
PMID:18669600 |
|
NCBI chr 8:104,270,858...104,420,955
Ensembl chr 8:104,270,881...104,420,953
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G |
PDE6C |
phosphodiesterase 6C |
increases degradation |
EXP |
PDE6C protein results in increased degradation of Cyclic GMP |
CTD |
PMID:18669600 |
|
NCBI chr14:105,010,974...105,122,628
Ensembl chr14:105,050,691...105,122,421
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G |
PRKG1 |
protein kinase cGMP-dependent 1 |
increases activity |
EXP |
Cyclic GMP results in increased activity of PRKG1 protein |
CTD |
PMID:18037907 |
|
NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,558,533...98,793,010
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G |
SLC4A2 |
solute carrier family 4 member 2 |
multiple interactions |
EXP |
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC4A2 protein binds to SLC4A2 protein] |
CTD |
PMID:10387099 |
|
NCBI chr18:6,149,459...6,166,622
Ensembl chr18:6,149,459...6,165,212
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] |
CTD |
PMID:7564105 |
|
NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554
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G |
NOS3 |
nitric oxide synthase 3 |
decreases expression |
EXP |
amprenavir results in decreased expression of NOS3 mRNA |
CTD |
PMID:16123675 |
|
NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
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G |
BCL2 |
BCL2 apoptosis regulator |
increases expression multiple interactions |
EXP |
Adenosine Triphosphate results in increased expression of BCL2 protein tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of BCL2 protein] |
CTD |
PMID:17997382 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CASP8 |
caspase 8 |
increases activity multiple interactions |
EXP |
Adenosine Triphosphate results in increased activity of CASP8 protein tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased activity of CASP8 protein] |
CTD |
PMID:17997382 |
|
NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G |
CYCS |
cytochrome c, somatic |
affects localization multiple interactions |
EXP |
Adenosine Triphosphate affects the localization of CYCS protein [Calcium co-treated with Phosphates co-treated with Adenosine Triphosphate] affects the localization of CYCS protein; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate affects the localization of CYCS protein] |
CTD |
PMID:16489745 PMID:17997382 |
|
NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
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G |
MYL9 |
myosin light chain 9 |
decreases phosphorylation multiple interactions |
EXP |
Adenosine Triphosphate results in decreased phosphorylation of MYL9 protein 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein] |
CTD |
PMID:10942722 |
|
NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,293
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G |
TNF |
tumor necrosis factor |
increases expression multiple interactions |
EXP |
Adenosine Triphosphate results in increased expression of TNF protein tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of TNF protein] |
CTD |
PMID:17997382 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
increases expression |
EXP |
Bucladesine results in increased expression of ATP1A1 protein |
CTD |
PMID:28438630 |
|
NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,508...104,384,547
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression |
EXP |
Chlorpyrifos results in increased expression of BAX mRNA |
CTD |
PMID:34399389 PMID:38565334 |
|
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of BCL2 mRNA |
CTD |
PMID:34399389 PMID:38565334 |
|
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CASP3 |
caspase 3 |
increases expression increases cleavage |
EXP |
Chlorpyrifos results in increased expression of CASP3 mRNA Chlorpyrifos results in increased cleavage of CASP3 mRNA |
CTD |
PMID:34399389 PMID:38565334 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CAT |
catalase |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of CAT mRNA |
CTD |
PMID:34399389 PMID:38565334 |
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NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
DAAM1 |
dishevelled associated activator of morphogenesis 1 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of DAAM1 mRNA; Chlorpyrifos results in decreased expression of DAAM1 protein |
CTD |
PMID:38565334 |
|
NCBI chr 1:188,335,335...188,511,094
Ensembl chr 1:188,335,384...188,511,096
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G |
FSCN1 |
fascin actin-bundling protein 1 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of FSCN1 mRNA; Chlorpyrifos results in decreased expression of FSCN1 protein |
CTD |
PMID:38565334 |
|
NCBI chr 3:4,134,173...4,143,275
Ensembl chr 3:4,134,177...4,143,286
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G |
GJA1 |
gap junction protein alpha 1 |
increases expression |
EXP |
Chlorpyrifos results in increased expression of GJA1 mRNA; Chlorpyrifos results in increased expression of GJA1 protein |
CTD |
PMID:38565334 |
|
NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156
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G |
GPX2 |
glutathione peroxidase 2 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of GPX2 mRNA |
CTD |
PMID:34399389 PMID:38565334 |
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NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
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G |
MYO10 |
myosin X |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of MYO10 mRNA; Chlorpyrifos results in decreased expression of MYO10 protein |
CTD |
PMID:38565334 |
|
NCBI chr16:5,907,111...6,145,485
Ensembl chr16:5,907,116...6,094,845
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of PTGS2 mRNA |
CTD |
PMID:38565334 |
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NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
SHAS2 |
hyaluronan synthase 2 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of SHAS2 mRNA |
CTD |
PMID:38565334 |
|
NCBI chr 4:17,583,154...17,613,524
Ensembl chr 4:17,596,492...17,615,480
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G |
SOD1 |
superoxide dismutase 1 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of SOD1 mRNA |
CTD |
PMID:34399389 PMID:38565334 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SOD2 |
superoxide dismutase 2 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of SOD2 mRNA |
CTD |
PMID:34399389 PMID:38565334 |
|
NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
TNFAIP6 |
TNF alpha induced protein 6 |
decreases expression |
EXP |
Chlorpyrifos results in decreased expression of TNFAIP6 mRNA |
CTD |
PMID:38565334 |
|
NCBI chr15:862,013...881,352
Ensembl chr15:862,015...881,461
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G |
APEH |
acylaminoacyl-peptide hydrolase |
decreases activity |
EXP |
chlorpyrifos-methyl results in decreased activity of APEH protein |
CTD |
PMID:10953051 |
|
NCBI chr13:32,205,863...32,214,517
Ensembl chr13:32,205,609...32,214,518
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G |
FGF10 |
fibroblast growth factor 10 |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF10 protein |
CTD |
PMID:14699094 |
|
NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509
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G |
FGF18 |
fibroblast growth factor 18 |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF18 protein |
CTD |
PMID:14699094 |
|
NCBI chr16:52,724,867...52,760,246
Ensembl chr16:52,725,356...52,759,791
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G |
FGF2 |
fibroblast growth factor 2 |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 protein |
CTD |
PMID:14699094 |
|
NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916
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G |
MDK |
midkine |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to MDK protein |
CTD |
PMID:14699094 |
|
NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,788...16,133,510
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G |
PTN |
pleiotrophin |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein |
CTD |
PMID:14699094 |
|
NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,787...12,309,044
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G |
ATOX1 |
antioxidant 1 copper chaperone |
increases expression |
EXP |
Copper Sulfate results in increased expression of ATOX1 mRNA |
CTD |
PMID:22585802 |
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NCBI chr16:71,299,321...71,314,598
Ensembl chr16:71,299,321...71,314,597
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G |
CCNB1 |
cyclin B1 |
increases secretion |
EXP |
Copper Sulfate results in increased secretion of CCNB1 protein |
CTD |
PMID:24521407 |
|
NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
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G |
COX17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
EXP |
Copper Sulfate results in decreased expression of COX17 mRNA |
CTD |
PMID:22585802 |
|
NCBI chr13:140,584,286...140,594,636
Ensembl chr13:140,584,363...140,587,621
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G |
GHRH |
growth hormone releasing hormone |
increases expression |
EXP |
Copper Sulfate results in increased expression of GHRH mRNA |
CTD |
PMID:21110139 |
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NCBI chr17:40,386,725...40,398,312
Ensembl chr17:40,387,344...40,397,857
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
Copper Sulfate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:17464326 |
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NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Copper Sulfate results in increased expression of HSPA5 mRNA |
CTD |
PMID:17464326 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
IGF1 |
insulin like growth factor 1 |
increases secretion |
EXP |
Copper Sulfate results in increased secretion of IGF1 protein |
CTD |
PMID:24521407 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
SST |
somatostatin |
decreases expression |
EXP |
Copper Sulfate results in decreased expression of SST mRNA; Copper Sulfate results in decreased expression of SST protein |
CTD |
PMID:21110139 |
|
NCBI chr13:125,337,560...125,338,742
Ensembl chr13:125,337,418...125,338,850
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G |
ALB |
albumin |
decreases uptake |
EXP |
cylindrospermopsin results in decreased uptake of ALB protein |
CTD |
PMID:33689780 |
|
NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
increases expression |
EXP |
cylindrospermopsin results in increased expression of ATP1A1 mRNA |
CTD |
PMID:33689780 |
|
NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,508...104,384,547
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G |
DAB2 |
DAB adaptor protein 2 |
decreases expression |
EXP |
cylindrospermopsin results in decreased expression of DAB2 mRNA |
CTD |
PMID:33689780 |
|
NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122
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G |
LRP2 |
LDL receptor related protein 2 |
decreases expression |
EXP |
cylindrospermopsin results in decreased expression of LRP2 mRNA |
CTD |
PMID:33689780 |
|
NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694
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G |
FGF10 |
fibroblast growth factor 10 |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF10 protein |
CTD |
PMID:14699094 |
|
NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509
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G |
FGF18 |
fibroblast growth factor 18 |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF18 protein |
CTD |
PMID:14699094 |
|
NCBI chr16:52,724,867...52,760,246
Ensembl chr16:52,725,356...52,759,791
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G |
FGF2 |
fibroblast growth factor 2 |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 protein |
CTD |
PMID:14699094 |
|
NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916
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G |
MDK |
midkine |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to MDK protein |
CTD |
PMID:14699094 |
|
NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,788...16,133,510
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G |
PTN |
pleiotrophin |
affects binding |
EXP |
[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein |
CTD |
PMID:14699094 |
|
NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,787...12,309,044
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G |
CASP1 |
caspase 1, apoptosis-related cysteine peptidase |
multiple interactions increases expression |
EXP |
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 mRNA] Dextran Sulfate results in increased expression of CASP1 mRNA; Dextran Sulfate results in increased expression of CASP1 protein |
CTD |
PMID:30270565 |
|
NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
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G |
IL18 |
interleukin 18 |
increases expression multiple interactions |
EXP |
Dextran Sulfate results in increased expression of IL18 mRNA [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA] |
CTD |
PMID:30270565 |
|
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions increases expression |
EXP |
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL1B mRNA; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA] |
CTD |
PMID:30270565 |
|
|
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions increases expression |
EXP |
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein] Dextran Sulfate results in increased expression of NLRP3 mRNA; Dextran Sulfate results in increased expression of NLRP3 protein |
CTD |
PMID:30270565 |
|
NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228
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G |
PYCARD |
PYD and CARD domain containing |
multiple interactions increases expression |
EXP |
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD protein Dextran Sulfate results in increased expression of PYCARD mRNA; Dextran Sulfate results in increased expression of PYCARD protein |
CTD |
PMID:30270565 |
|
NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
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G |
ACHE |
acetylcholinesterase |
decreases activity |
EXP |
Diazinon results in decreased activity of ACHE protein |
CTD |
PMID:21467751 |
|
NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
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G |
ACHE |
acetylcholinesterase |
decreases activity |
EXP |
Dichlorvos results in decreased activity of ACHE protein |
CTD |
PMID:21467751 |
|
NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
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G |
APEH |
acylaminoacyl-peptide hydrolase |
decreases activity |
EXP |
Dichlorvos results in decreased activity of APEH protein |
CTD |
PMID:10953051 |
|
NCBI chr13:32,205,863...32,214,517
Ensembl chr13:32,205,609...32,214,518
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Dichlorvos results in decreased activity of BCHE protein |
CTD |
PMID:4631366 |
|
NCBI chr13:104,946,732...105,007,568
|
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G |
APEH |
acylaminoacyl-peptide hydrolase |
decreases activity |
EXP |
Isoflurophate results in decreased activity of APEH protein |
CTD |
PMID:10953051 |
|
NCBI chr13:32,205,863...32,214,517
Ensembl chr13:32,205,609...32,214,518
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Isoflurophate results in decreased activity of BCHE protein |
CTD |
PMID:4631366 |
|
NCBI chr13:104,946,732...105,007,568
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G |
SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
increases uptake multiple interactions |
EXP |
SLCO1A2 protein results in increased uptake of estrone sulfate Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; cefquinome inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Chlortetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Penicillins inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate] |
CTD |
PMID:31287969 |
|
NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
[laminaran co-treated with fucoidan co-treated with Minerals] promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
CTD |
PMID:21948611 |
|
NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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G |
EDN1 |
endothelin 1 |
multiple interactions |
EXP |
Glyburide inhibits the reaction [Carvedilol results in decreased expression of EDN1 protein] |
CTD |
PMID:18840580 |
|
NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
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G |
ALPL |
alkaline phosphatase, biomineralization associated |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA |
CTD |
PMID:30481989 |
|
NCBI chr 6:79,589,695...79,649,646
Ensembl chr 6:79,589,045...79,649,644
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G |
BCL2L1 |
BCL2 like 1 |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BCL2L1 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
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G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
[Troglitazone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CASP3 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CEBPA |
CCAAT enhancer binding protein alpha |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004
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G |
CTNNB1 |
catenin beta 1 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
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G |
FABP4 |
fatty acid binding protein 4 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896
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G |
IGF1 |
insulin like growth factor 1 |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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G |
IGF1R |
insulin like growth factor 1 receptor |
multiple interactions |
EXP |
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
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G |
RUNX2 |
RUNX family transcription factor 2 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA |
CTD |
PMID:30481989 |
|
NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687
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G |
SPP1 |
secreted phosphoprotein 1 |
multiple interactions |
EXP |
2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] |
CTD |
PMID:30481989 |
|
NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
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G |
PSP-I |
porcine seminal protein I |
multiple interactions |
EXP |
zinc chloride promotes the reaction [PSP-I protein binds to Heparin]; Zinc promotes the reaction [PSP-I protein binds to Heparin] |
CTD |
PMID:16819821 |
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NCBI chr14:132,302,376...132,309,388
Ensembl chr14:132,302,352...132,308,106
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G |
AKT2 |
AKT serine/threonine kinase 2 |
increases expression |
EXP |
Malathion results in increased expression of AKT2 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression |
EXP |
Malathion results in increased expression of BAX mRNA |
CTD |
PMID:31535366 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression multiple interactions |
EXP |
Malathion results in decreased expression of BCL2 mRNA Melatonin inhibits the reaction [Malathion results in decreased expression of BCL2 mRNA] |
CTD |
PMID:31535366 |
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NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CAT |
catalase |
decreases expression multiple interactions |
EXP |
Malathion results in decreased expression of CAT mRNA Melatonin inhibits the reaction [Malathion results in decreased expression of CAT mRNA] |
CTD |
PMID:31535366 |
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NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
decreases expression |
EXP |
Malathion results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
decreases expression |
EXP |
Malathion results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 3:102,195,743...102,205,687
Ensembl chr 3:102,195,741...102,205,683
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G |
DUOX2 |
dual oxidase 2 |
decreases expression |
EXP |
Malathion results in decreased expression of DUOX2 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 1:126,620,468...126,641,406
Ensembl chr 1:126,620,510...126,641,406
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G |
GPX4 |
glutathione peroxidase 4 |
increases expression |
EXP |
Malathion results in increased expression of GPX4 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
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G |
GPX6 |
glutathione peroxidase 6 |
increases expression |
EXP |
Malathion results in increased expression of GPX6 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 7:22,256,013...22,267,992
Ensembl chr 7:22,256,038...22,267,992
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G |
LOC106504562 |
glutathione S-transferase alpha M14 |
decreases expression |
EXP |
Malathion results in decreased expression of GSTA1 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 7:46,553,813...46,567,596
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G |
MT-CO1 |
mitochondrially encoded cytochrome c oxidase I |
affects expression |
EXP |
Malathion affects the expression of COX1 mRNA |
CTD |
PMID:17454254 |
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NCBI chr MT:6,511...8,055
Ensembl chr MT:6,511...8,055
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G |
MT-CO3 |
mitochondrially encoded cytochrome c oxidase III |
affects expression |
EXP |
Malathion affects the expression of COX3 mRNA |
CTD |
PMID:17454254 |
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NCBI chr MT:9,800...10,583
Ensembl chr MT:9,800...10,583
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G |
PLIN2 |
perilipin 2 |
multiple interactions decreases expression |
EXP |
Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PLIN2 protein] Malathion results in decreased expression of PLIN2 mRNA; Malathion results in decreased expression of PLIN2 protein |
CTD |
PMID:31535366 |
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NCBI chr 1:203,683,867...203,709,277
Ensembl chr 1:203,683,862...203,709,273
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions decreases expression |
EXP |
Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG mRNA]; Melatonin inhibits the reaction [Malathion results in decreased expression of PPARG protein] Malathion results in decreased expression of PPARG mRNA; Malathion results in decreased expression of PPARG protein |
CTD |
PMID:31535366 |
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NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
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G |
SLC34A2 |
solute carrier family 34 member 2 |
increases expression |
EXP |
Malathion results in increased expression of SLC34A2 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 8:19,481,127...19,507,903
Ensembl chr 8:19,481,198...19,509,666
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G |
SOD2 |
superoxide dismutase 2 |
increases expression |
EXP |
Malathion results in increased expression of SOD2 mRNA |
CTD |
PMID:31535366 |
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
SORD |
sorbitol dehydrogenase |
increases expression |
EXP |
Malathion results in increased expression of SORD mRNA |
CTD |
PMID:31535366 |
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NCBI chr 1:126,659,198...126,701,084
Ensembl chr 1:126,655,156...126,701,138
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G |
TP53 |
tumor protein p53 |
increases expression multiple interactions |
EXP |
Malathion results in increased expression of TP53 mRNA Melatonin inhibits the reaction [Malathion results in increased expression of TP53 mRNA] |
CTD |
PMID:31535366 |
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NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
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G |
HTR2C |
5-hydroxytryptamine receptor 2C |
affects binding multiple interactions |
EXP |
mesulergine binds to HTR2C protein 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [mesulergine binds to HTR2C protein] |
CTD |
PMID:11927170 |
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NCBI chr X:94,053,415...94,313,352
Ensembl chr X:94,053,456...94,313,355
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G |
MYL9 |
myosin light chain 9 |
decreases phosphorylation |
EXP |
ML 7 results in decreased phosphorylation of MYL9 protein |
CTD |
PMID:10942722 |
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NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,293
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G |
MYLK |
myosin light chain kinase |
multiple interactions |
EXP |
[ML 7 results in decreased activity of MYLK protein] which results in decreased uptake of Calcium |
CTD |
PMID:9506478 |
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NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668
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G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP |
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Brimonidine Tartrate results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:17680988 |
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NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728
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G |
IL6 |
interleukin 6 |
decreases expression multiple interactions |
EXP |
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of IL6 protein N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of IL6 protein] |
CTD |
PMID:24105867 |
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NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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G |
PRKACA |
protein kinase cAMP-activated catalytic subunit alpha |
multiple interactions |
EXP |
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Amphotericin B results in increased expression of PRKACG protein] |
CTD |
PMID:24105867 |
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NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
NAD promotes the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
|
NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
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G |
ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
multiple interactions |
EXP |
NAD promotes the reaction [Hydrogen Peroxide results in decreased activity of ALDH7A1 protein] |
CTD |
PMID:21296058 |
|
NCBI chr 2:129,663,226...129,709,728
Ensembl chr 2:129,662,969...129,709,705
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G |
LOC110256483 |
carbonyl reductase [NADPH] 1-like |
multiple interactions affects binding |
EXP |
NADP inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of CBR1 protein] NADP binds to CBR1 protein |
CTD |
PMID:15145449 |
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NCBI chr13:199,713,741...199,719,535
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G |
LOC110256483 |
carbonyl reductase [NADPH] 1-like |
affects binding multiple interactions |
EXP |
NADP binds to CBR1 protein NADP inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of CBR1 protein] |
CTD |
PMID:15145449 |
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NCBI chr13:199,713,741...199,719,535
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
nimesulide inhibits the reaction [Hydrogen Peroxide results in increased expression of HSPA5 protein] |
CTD |
PMID:20665602 |
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NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
ACHE |
acetylcholinesterase |
decreases activity multiple interactions |
EXP |
Paraoxon results in decreased activity of ACHE protein asoxime chloride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] |
CTD |
PMID:19428926 PMID:20156534 PMID:20971170 PMID:22230262 |
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NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
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G |
BCHE |
butyrylcholinesterase |
decreases activity |
EXP |
Paraoxon results in decreased activity of BCHE protein |
CTD |
PMID:4631366 |
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NCBI chr13:104,946,732...105,007,568
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G |
ALB |
albumin |
affects binding |
EXP |
perfluorobutanesulfonic acid binds to ALB protein |
CTD |
PMID:38518100 |
|
NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696
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G |
ABCB4 |
ATP binding cassette subfamily B member 4 |
increases export multiple interactions |
EXP |
ABCB4 protein results in increased export of Phosphatidylcholines Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines] |
CTD |
PMID:21056966 |
|
NCBI chr 9:93,171,371...93,262,124
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G |
PDIA3 |
protein disulfide isomerase family A member 3 |
increases hydrolysis |
EXP |
PDIA3 protein results in increased hydrolysis of Phosphatidylcholines |
CTD |
PMID:16798117 |
|
NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
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G |
ACHE |
acetylcholinesterase |
multiple interactions decreases activity |
EXP |
Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]; Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein] |
CTD |
PMID:21414391 |
|
NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
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G |
CALR |
calreticulin |
increases expression |
EXP |
sulfamethoxazole hydroxylamine results in increased expression of CALR protein |
CTD |
PMID:16005169 |
|
NCBI chr 2:66,098,263...66,102,074
Ensembl chr 2:66,098,229...66,102,132
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G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
decreases expression |
EXP |
sulfamethoxazole hydroxylamine results in decreased expression of HSP90B1 protein |
CTD |
PMID:16005169 |
|
NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
sulfamethoxazole hydroxylamine results in increased expression of HSPA5 protein |
CTD |
PMID:16005169 |
|
NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
CASP1 |
caspase 1, apoptosis-related cysteine peptidase |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in increased expression of and results in increased cleavage of CASP1 protein] |
CTD |
PMID:36281498 |
|
NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328
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G |
CAT |
catalase |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in decreased expression of CAT mRNA] |
CTD |
PMID:36281498 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in decreased expression of GPX1 mRNA] |
CTD |
PMID:36281498 |
|
NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
GPX4 |
glutathione peroxidase 4 |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in decreased expression of GPX4 mRNA] |
CTD |
PMID:36281498 |
|
NCBI chr 2:77,321,568...77,323,931
Ensembl chr 2:77,320,464...77,323,931
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G |
GSDMD |
gasdermin D |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in increased expression of GSDMD protein] |
CTD |
PMID:36281498 |
|
NCBI chr 4:995,753...1,001,964
Ensembl chr 4:995,763...1,000,271
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in increased expression of IL1B protein] |
CTD |
PMID:36281498 |
|
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in increased expression of NLRP3 protein] |
CTD |
PMID:36281498 |
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NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228
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NOS2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in decreased expression of INOS mRNA] |
CTD |
PMID:36281498 |
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NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
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PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in decreased expression of PTGS2 mRNA] |
CTD |
PMID:36281498 |
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NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
PYCARD |
PYD and CARD domain containing |
multiple interactions |
EXP |
Taurine inhibits the reaction [ochratoxin A results in increased expression of PYCARD protein] |
CTD |
PMID:36281498 |
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NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
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ABCB11 |
ATP binding cassette subfamily B member 11 |
increases transport |
EXP |
ABCB11 protein results in increased transport of Taurocholic Acid |
CTD |
PMID:21056966 |
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NCBI chr15:75,402,296...75,487,092
Ensembl chr15:75,402,396...75,486,403
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SLCO1A2 |
solute carrier organic anion transporter family member 1A2 |
increases uptake multiple interactions |
EXP |
SLCO1A2 protein results in increased uptake of Taurocholic Acid Amoxicillin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; cefquinome inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Clarithromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; daidzein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Doxycycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; epigallocatechin gallate inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Erythromycin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Genistein inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; naringin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Oxytetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Penicillins inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Tetracycline inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] |
CTD |
PMID:31287969 |
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NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of ATF4 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of ATF4 mRNA] |
CTD |
PMID:37207789 PMID:38845341 |
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NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of ATF6 mRNA] |
CTD |
PMID:37207789 |
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NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA] |
CTD |
PMID:38845341 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions |
EXP |
ursodoxicoltaurine promotes the reaction [bisphenol A results in increased expression of BCL2 mRNA] |
CTD |
PMID:38845341 |
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NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
CASP3 |
caspase 3 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of CASP3 mRNA] |
CTD |
PMID:38845341 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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CAT |
catalase |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of CAT mRNA] |
CTD |
PMID:37207789 |
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NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of DDIT3 mRNA] |
CTD |
PMID:37207789 PMID:38845341 |
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NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of HSPA5 mRNA] |
CTD |
PMID:37207789 PMID:38845341 |
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NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [Cadmium results in decreased expression of PTGS1 mRNA] |
CTD |
PMID:37207789 |
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NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in decreased expression of PTGS2 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in decreased expression of PTGS2 mRNA] |
CTD |
PMID:37207789 PMID:38845341 |
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NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
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G |
PTX3 |
pentraxin 3 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [bisphenol A results in decreased expression of PTX3 mRNA]; ursodoxicoltaurine inhibits the reaction [Cadmium results in decreased expression of PTX3 mRNA] |
CTD |
PMID:37207789 PMID:38845341 |
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NCBI chr13:97,273,594...97,279,570
Ensembl chr13:97,273,594...97,279,569
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [Cadmium results in increased expression of SOD1 mRNA] |
CTD |
PMID:37207789 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
ursodoxicoltaurine affects the reaction [Cadmium results in increased expression of SOD2 mRNA] |
CTD |
PMID:37207789 |
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
TNFAIP6 |
TNF alpha induced protein 6 |
multiple interactions |
EXP |
[ursodoxicoltaurine co-treated with Cadmium] results in increased expression of TNFAIP6 mRNA; ursodoxicoltaurine inhibits the reaction [Cadmium results in decreased expression of TNFAIP6 mRNA] |
CTD |
PMID:37207789 |
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NCBI chr15:862,013...881,352
Ensembl chr15:862,015...881,461
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G |
XBP1 |
X-box binding protein 1 |
multiple interactions |
EXP |
ursodoxicoltaurine inhibits the reaction [Cadmium results in increased splicing of XBP1 mRNA] |
CTD |
PMID:37207789 |
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NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526
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G |
ACHE |
acetylcholinesterase |
multiple interactions decreases activity |
EXP |
N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [VX results in decreased activity of ACHE protein] |
CTD |
PMID:20888357 |
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NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP |
Zinc Sulfate results in increased expression of BAX mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BAX mRNA] |
CTD |
PMID:28803810 |
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NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BECN1 |
beclin 1 |
increases expression multiple interactions |
EXP |
Zinc Sulfate results in increased expression of BECN1 protein 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of BECN1 protein] |
CTD |
PMID:28803810 |
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NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
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G |
CASP3 |
caspase 3 |
multiple interactions increases expression increases cleavage |
EXP |
3-methyladenine inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP3 protein] Zinc Sulfate results in increased expression of CASP3 mRNA |
CTD |
PMID:28803810 |
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NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CASP6 |
caspase 6 |
increases expression |
EXP |
Zinc Sulfate results in increased expression of CASP6 mRNA |
CTD |
PMID:28803810 |
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NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045
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G |
CASP8 |
caspase 8 |
multiple interactions increases cleavage |
EXP |
3-methyladenine inhibits the reaction [Zinc Sulfate results in increased cleavage of CASP8 protein] |
CTD |
PMID:28803810 |
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NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
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G |
CYCS |
cytochrome c, somatic |
increases expression multiple interactions |
EXP |
Zinc Sulfate results in increased expression of CYCS mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in increased expression of CYCS mRNA] |
CTD |
PMID:28803810 |
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NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA] |
CTD |
PMID:32280687 |
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NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
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G |
LOC110258578 |
interleukin-1 beta-like |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in increased expression of IL1B mRNA] |
CTD |
PMID:32280687 |
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G |
MAP1LC3A |
microtubule associated protein 1 light chain 3 alpha |
increases expression |
EXP |
Zinc Sulfate results in increased expression of MAP1LC3A mRNA |
CTD |
PMID:28803810 |
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NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505
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G |
MT1A |
metallothionein 1A |
increases expression |
EXP |
Zinc Sulfate results in increased expression of MT1A mRNA |
CTD |
PMID:25895165 |
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NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:32280687 |
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NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G |
SLC30A1 |
solute carrier family 30 member 1 |
increases expression |
EXP |
Zinc Sulfate results in increased expression of SLC30A1 mRNA |
CTD |
PMID:25895165 |
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NCBI chr 9:131,633,586...131,636,934
Ensembl chr 9:131,633,585...131,640,672
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G |
SLC39A10 |
solute carrier family 39 member 10 |
decreases expression increases expression |
EXP |
Zinc Sulfate results in decreased expression of SLC39A10 mRNA Zinc Sulfate results in increased expression of SLC39A10 mRNA |
CTD |
PMID:16804107 |
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NCBI chr15:99,584,830...99,724,621
Ensembl chr15:99,584,872...99,724,611
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in decreased expression of SOD1 mRNA] |
CTD |
PMID:32280687 |
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NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729
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G |
SQSTM1 |
sequestosome 1 |
increases expression multiple interactions decreases expression |
EXP |
Zinc Sulfate results in increased expression of SQSTM1 mRNA 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein] |
CTD |
PMID:28803810 |
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NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938
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G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
Zinc Sulfate inhibits the reaction [Diquat results in increased expression of TNF mRNA] |
CTD |
PMID:32280687 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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