vitamin E - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	vitamin E	go back to main search page
Accession:	CHEBI:33234	browse the term
Definition:	Any member of a group of fat-soluble chromanols that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen.
Synonyms:	related_synonym:	vitamin E vitamer; vitamin E vitamers; vitamins E
	alt_id:	MESH:D014810
	xref_mesh:	MESH:D024502
	xref:	MetaCyc:Vitamin-E; PMID:33684201; PMID:33847203; PMID:33896432; PMID:34277234; PMID:34278890; PMID:7898412; PMID:7901680; Wikipedia:Vitamin_E

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Genes (1873)

vitamin E

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angio-associated, migratory cell protein

increases expression

Vitamin E results in increased expression of AAMP mRNA

NCBI chr 9:75,863,382...75,869,188
Ensembl chr 9:75,863,389...75,868,547

G

aminoadipate-semialdehyde synthase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNA
Vitamin E results in decreased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

ATP binding cassette subfamily B member 11

decreases expression

Vitamin E results in decreased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily C member 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

abhydrolase domain containing 14A

decreases expression

Vitamin E results in decreased expression of ABHD14A mRNA

NCBI chr 8:107,079,139...107,089,004
Ensembl chr 8:107,079,144...107,086,985

G

abhydrolase domain containing 2, acylglycerol lipase

decreases expression
increases expression

Vitamin E results in decreased expression of ABHD2 mRNA
Vitamin E results in increased expression of ABHD2 mRNA

NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

Vitamin E results in increased expression of ABHD4 mRNA

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

acetyl-CoA acyltransferase 2

increases expression

Vitamin E results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acyl-CoA dehydrogenase short chain

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ACADS mRNA
Vitamin E results in increased expression of ACADS mRNA

NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898

G

acetylcholinesterase

multiple interactions

[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
[Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]

PMID:11814146 PMID:20663516 PMID:23619517 PMID:29233033

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

aconitase 2

increases expression

Vitamin E results in increased expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA thioesterase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ACOT2 mRNA
Vitamin E results in increased expression of ACOT2 mRNA

NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245

G

acid phosphatase 1

decreases expression

Vitamin E results in decreased expression of ACP1 mRNA

NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021

G

actin alpha 2, smooth muscle

decreases expression

Vitamin E results in decreased expression of ACTA2 mRNA

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin, beta

increases expression

Vitamin E results in increased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actinin alpha 4

increases expression

Vitamin E results in increased expression of ACTN4 mRNA

NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847

G

actin related protein 1A

increases expression

Vitamin E results in increased expression of ACTR1A mRNA

NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495

G

actin related protein 1B

increases expression

Vitamin E results in increased expression of ACTR1B mRNA

NCBI chr 9:38,928,819...38,938,483
Ensembl chr 9:38,929,912...38,938,507

G

activin A receptor type 2A

decreases expression

Vitamin E results in decreased expression of ACVR2A mRNA

NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968

G

ADAM metallopeptidase domain 17

decreases expression

Vitamin E results in decreased expression of ADAM17 mRNA

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

decreases expression

Vitamin E results in decreased expression of ADAMTS5 mRNA

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

ArfGAP with dual PH domains 1

increases expression

Vitamin E results in increased expression of ADAP1 mRNA

NCBI chr12:15,323,913...15,376,110
Ensembl chr12:15,324,209...15,380,831

G

adenosine deaminase, RNA-specific, B1

decreases expression

Vitamin E results in decreased expression of ADARB1 mRNA

NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852

G

adenylate cyclase 2

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ADCY2 mRNA

NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236

G

adenylate cyclase 6

increases expression

Vitamin E results in increased expression of ADCY6 mRNA

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

G

adducin 1

increases expression

Vitamin E results in increased expression of ADD1 mRNA

NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182

G

adducin 3

decreases expression

Vitamin E results in decreased expression of ADD3 mRNA

NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124

G

adhesion G protein-coupled receptor B1

increases expression

Vitamin E results in increased expression of ADGRB1 mRNA

NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

decreases expression

Vitamin E results in decreased expression of ADH7 mRNA

NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182

G

adiponectin, C1Q and collagen domain containing

multiple interactions

Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ mRNA]; Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein]

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adipose secreted signaling protein

increases expression
multiple interactions

Vitamin E results in increased expression of ADISSP mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ADISSP mRNA

NCBI chr 3:118,364,730...118,378,881
Ensembl chr 3:118,362,363...118,378,838

G

adrenoceptor alpha 2C

increases expression

Vitamin E results in increased expression of ADRA2C mRNA

NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

Vitamin E results in increased expression of ADRM1 mRNA

NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195

G

AE binding protein 1

increases expression

Vitamin E results in increased expression of AEBP1 mRNA

NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877

G

apoptosis enhancing nuclease

increases expression

Vitamin E results in increased expression of AEN mRNA

NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523

G

1-acylglycerol-3-phosphate O-acyltransferase 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of AGPAT2 mRNA

NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371

G

agrin

decreases expression

Vitamin E results in decreased expression of AGRN mRNA

NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003

G

ATP/GTP binding carboxypeptidase 1

decreases expression

Vitamin E results in decreased expression of AGTPBP1 mRNA

NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869

G

AHNAK nucleoprotein

increases expression

Vitamin E results in increased expression of AHNAK mRNA

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

AHNAK nucleoprotein 2

increases expression

Vitamin E results in increased expression of AHNAK2 mRNA

NCBI chr 6:131,830,668...131,876,311

G

aryl hydrocarbon receptor

decreases expression

Vitamin E results in decreased expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

activator of Hsp90 ATPase activity 1

increases expression

Vitamin E results in increased expression of AHSA1 mRNA

NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of AIMP1 mRNA
Vitamin E results in decreased expression of AIMP1 mRNA

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

adenylate kinase 1

increases expression

Vitamin E results in increased expression of AK1 mRNA

NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041

G

adenylate kinase 3

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of AK3 mRNA

NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625

G

A-kinase anchoring protein 13

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of AKAP13 mRNA
Vitamin E results in decreased expression of AKAP13 mRNA

NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646

G

aldo-keto reductase family 1 member B1

increases expression

Vitamin E results in increased expression of AKR1B1 mRNA

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1 member B10

increases expression

Vitamin E results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C2

increases expression

Vitamin E results in increased expression of AKR1C2 mRNA

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

AKT serine/threonine kinase 1

increases expression
multiple interactions

Vitamin E results in increased expression of AKT1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]

PMID:19244175 PMID:21911000

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aminolevulinate dehydratase

multiple interactions

Vitamin E inhibits the reaction [lead acetate results in decreased activity of ALAD protein]

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

albumin

multiple interactions

Vitamin E inhibits the reaction [Ethanol results in decreased expression of ALB protein]
Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]
[Quercetin co-treated with Vitamin E] inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]; Vitamin E inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]

PMID:17927767 PMID:21086752 PMID:23348005

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 6 family, member A1

decreases expression

Vitamin E results in decreased expression of ALDH6A1 mRNA

NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656

G

aldolase, fructose-bisphosphate A

increases expression

Vitamin E results in increased expression of ALDOA mRNA

NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182

G

ALG3, alpha-1,3- mannosyltransferase

increases expression

Vitamin E results in increased expression of ALG3 mRNA

NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912

G

ALG9, alpha-1,2-mannosyltransferase

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ALG9 mRNA

NCBI chr 8:51,117,057...51,188,790
Ensembl chr 8:51,119,365...51,182,261

G

alkB homolog 1, histone H2A dioxygenase

decreases expression

Vitamin E results in decreased expression of ALKBH1 mRNA

NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759

G

arachidonate 5-lipoxygenase

decreases activity
multiple interactions

Vitamin E results in decreased activity of ALOX5 protein
[Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein

PMID:11325678 PMID:12200813 PMID:22223226

NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743

G

alkaline phosphatase, biomineralization associated

multiple interactions

Vitamin E inhibits the reaction [Doxorubicin results in decreased activity of ALPL protein]; Vitamin E inhibits the reaction [Hexachlorobenzene results in increased activity of ALPL protein]; Vitamin E inhibits the reaction [Tramadol results in increased expression of ALPL protein]

PMID:30064338 PMID:31618080 PMID:32810592

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

autophagy and beclin 1 regulator 1

increases expression

Vitamin E results in increased expression of AMBRA1 mRNA

NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221

G

anaphase promoting complex subunit 15

increases expression

Vitamin E results in increased expression of ANAPC15 mRNA

NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145

G

androgen regulated protein

decreases expression

Vitamin E results in decreased expression of ANDPRO mRNA

NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966

G

angiopoietin 1

decreases expression

Vitamin E results in decreased expression of ANGPT1 mRNA

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

G

ankyrin 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNA
Vitamin E results in decreased expression of ANK3 mRNA

NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300

G

ankyrin repeat domain 12

decreases expression

Vitamin E results in decreased expression of ANKRD12 mRNA

NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911

G

acidic nuclear phosphoprotein 32 family member B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ANP32B mRNA
Vitamin E results in decreased expression of ANP32B mRNA

NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717

G

annexin A6

increases expression

Vitamin E results in increased expression of ANXA6 mRNA

NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433

G

adaptor related protein complex 1 subunit mu 2

increases expression

Vitamin E results in increased expression of AP1M2 mRNA

NCBI chr 8:19,838,579...19,856,560
Ensembl chr 8:19,838,580...19,856,482

G

adaptor related protein complex 2 subunit alpha 2

increases expression

Vitamin E results in increased expression of AP2A2 mRNA

NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603

G

adaptor related protein complex 2 subunit mu 1

increases expression

Vitamin E results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

adaptor related protein complex 2 subunit sigma 1

increases expression

Vitamin E results in increased expression of AP2S1 mRNA

NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905

G

adaptor related protein complex 3 subunit sigma 2

increases expression

Vitamin E results in increased expression of AP3S2 mRNA

NCBI chr 1:133,818,825...133,859,269
Ensembl chr 1:133,818,825...133,859,322

G

amyloid beta precursor protein binding family B member 2

decreases expression

Vitamin E results in decreased expression of APBB2 mRNA

NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

Vitamin E results in increased expression of APEX1 mRNA

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

amyloid beta precursor like protein 2

increases expression

Vitamin E results in increased expression of APLP2 mRNA

NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855

G

apolipoprotein A1

increases expression

Vitamin E results in increased expression of APOA1 protein

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein B

multiple interactions

[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; Vitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Vitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]]

PMID:17237316 PMID:17475462

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

apolipoprotein E

multiple interactions

Vitamin E inhibits the reaction [APOE mutant form results in increased abundance of 8,12-iso-isoprostane F2alpha-VI]

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

apolipoprotein M

increases expression

Vitamin E results in increased expression of APOM mRNA

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

amyloid beta precursor protein

decreases expression
multiple interactions

Vitamin E results in decreased expression of APP mRNA
Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein]
Vitamin E inhibits the reaction [APP protein modified form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]

PMID:12039845 PMID:12117551 PMID:15223066 PMID:19244175

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

amyloid beta precursor protein binding protein 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of APPBP2 mRNA
Vitamin E results in increased expression of APPBP2 mRNA

NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835

G

aquaporin 1

increases expression

Vitamin E results in increased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 3 (Gill blood group)

increases expression
multiple interactions

Vitamin E results in increased expression of AQP3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 4

multiple interactions

Vitamin E inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein]
Vitamin E inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]

PMID:20648640 PMID:30914277

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

G

A-Raf proto-oncogene, serine/threonine kinase

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ARAF mRNA

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

G

ADP-ribosylation factor 3

increases expression

Vitamin E results in increased expression of ARF3 mRNA

NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002

G

ADP-ribosylation factor 5

increases expression

Vitamin E results in increased expression of ARF5 mRNA

NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441

G

Rho GTPase activating protein 10

increases expression

Vitamin E results in increased expression of ARHGAP10 mRNA

NCBI chr19:30,448,572...30,710,315
Ensembl chr19:30,448,637...30,710,313

G

Rho GTPase activating protein 8

increases expression

Vitamin E results in increased expression of ARHGAP8 mRNA

NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093

G

Rho GDP dissociation inhibitor alpha

increases expression

Vitamin E results in increased expression of ARHGDIA mRNA

NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023

G

ariadne RBR E3 ubiquitin protein ligase 1

decreases expression

Vitamin E results in decreased expression of ARIH1 mRNA

NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245

G

ADP-ribosylation factor like GTPase 4D

increases expression

Vitamin E results in increased expression of ARL4D mRNA

NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836

G

ADP-ribosylation factor like GTPase 6 interacting protein 4

increases expression

Vitamin E results in increased expression of ARL6IP4 mRNA

NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799

G

actin related protein 2/3 complex, subunit 1A

increases expression

Vitamin E results in increased expression of ARPC1A mRNA

NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330

G

actin related protein 2/3 complex, subunit 4

increases expression

Vitamin E results in increased expression of ARPC4 mRNA

NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

increases expression

Vitamin E results in increased expression of ASAP3 mRNA

NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073

G

ankyrin repeat and SOCS box-containing 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ASB1 mRNA
Vitamin E results in increased expression of ASB1 mRNA

NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376

G

ASXL transcriptional regulator 1

decreases expression

Vitamin E results in decreased expression of ASXL1 mRNA

NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538

G

activating transcription factor 2

increases phosphorylation

Vitamin E results in increased phosphorylation of ATF2 protein

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

activating transcription factor 3

decreases expression

Vitamin E results in decreased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 5

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ATF5 mRNA
Vitamin E results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

autophagy related 12

decreases expression

Vitamin E results in decreased expression of ATG12 mRNA

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

ATM interactor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of ATMIN mRNA
Vitamin E results in decreased expression of ATMIN mRNA

NCBI chr19:44,996,506...45,013,606
Ensembl chr19:44,996,356...45,013,605

G

antioxidant 1 copper chaperone

increases expression

Vitamin E results in increased expression of ATOX1 mRNA

NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950

G

ATP synthase F1 subunit beta

increases expression

Vitamin E results in increased expression of ATP5F1B mRNA

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase F1 subunit gamma

decreases expression

Vitamin E results in decreased expression of ATP5F1C mRNA

NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367

G

ATP synthase membrane subunit e

decreases expression

Vitamin E results in decreased expression of ATP5ME mRNA

NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013

G

ATPase H+ transporting accessory protein 2

decreases expression

Vitamin E results in decreased expression of ATP6AP2 mRNA

NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918

G

ATPase H+ transporting V0 subunit D1

increases expression

Vitamin E results in increased expression of ATP6V0D1 mRNA

NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450

G

ATPase H+ transporting V1 subunit C1

decreases expression

Vitamin E results in decreased expression of ATP6V1C1 mRNA

NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278

G

ATPase phospholipid transporting 8B1

decreases expression

Vitamin E results in decreased expression of ATP8B1 mRNA

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

ATRX, chromatin remodeler

decreases expression
multiple interactions

Vitamin E results in decreased expression of ATRX mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

ataxin 3

decreases expression

Vitamin E results in decreased expression of ATXN3 mRNA

NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902

G

ataxin 7

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ATXN7 mRNA
Vitamin E results in decreased expression of ATXN7 mRNA

NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106

G

activator of transcription and developmental regulator AUTS2

decreases expression

Vitamin E results in decreased expression of AUTS2 mRNA

NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416

G

Axl receptor tyrosine kinase

decreases expression

Vitamin E results in decreased expression of AXL mRNA

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

bile acid CoA:amino acid N-acyltransferase

increases expression

Vitamin E results in increased expression of BAAT mRNA

NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685

G

BRISC and BRCA1 A complex member 1

increases expression

Vitamin E results in increased expression of BABAM1 mRNA

NCBI chr16:18,068,830...18,074,938
Ensembl chr16:18,068,884...18,074,923

G

BRISC and BRCA1 A complex member 2

increases expression

Vitamin E results in increased expression of BABAM2 mRNA

NCBI chr 6:24,369,021...24,788,416
Ensembl chr 6:24,369,022...24,833,951

G

BAG cochaperone 5

decreases expression

Vitamin E results in decreased expression of BAG5 mRNA

NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970

G

BAG cochaperone 6

increases expression

Vitamin E results in increased expression of BAG6 mRNA

NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657

G

BAF nuclear assembly factor 1

increases expression

Vitamin E results in increased expression of BANF1 mRNA

NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188

G

BRCA1 associated deubiquitinase 1

increases expression

Vitamin E results in increased expression of BAP1 mRNA

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

BRCA1 associated RING domain 1

decreases expression

Vitamin E results in decreased expression of BARD1 mRNA

NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265

G

basic leucine zipper ATF-like transcription factor

increases expression

Vitamin E results in increased expression of BATF mRNA

NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051

G

BCL2 associated X, apoptosis regulator

multiple interactions
affects expression
increases expression

Vitamin E inhibits the reaction [bioallethrin results in increased expression of BAX protein]; Vitamin E inhibits the reaction [cinnamaldehyde results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of BAX protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased expression of BAX protein]
[Vitamin E co-treated with Folic Acid] affects the expression of BAX protein; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased expression of BAX protein]
Vitamin E affects the expression of BAX protein
Vitamin E results in increased expression of BAX protein

PMID:11166918 PMID:15566391 PMID:16054126 PMID:16933212 PMID:22020378 More...

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

bromodomain adjacent to zinc finger domain, 1A

decreases expression

Vitamin E results in decreased expression of BAZ1A mRNA

NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459

G

bromodomain adjacent to zinc finger domain, 1B

increases expression

Vitamin E results in increased expression of BAZ1B mRNA

NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426

G

BBX high mobility group box domain containing

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BBX mRNA
Vitamin E results in decreased expression of BBX mRNA

NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251

G

B-cell receptor-associated protein 31

increases expression

Vitamin E results in increased expression of BCAP31 mRNA

NCBI chr X:151,397,567...151,429,666
Ensembl chr X:151,397,576...151,428,506

G

butyrylcholinesterase

multiple interactions

[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein]

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL11 transcription factor A

decreases expression

Vitamin E results in decreased expression of BCL11A mRNA

NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180

G

BCL2, apoptosis regulator

multiple interactions
increases expression

[Vitamin E co-treated with Curcumin] results in decreased expression of BCL2 protein; Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BCL2 protein]
Vitamin E results in increased expression of BCL2 mRNA
[Vitamin E co-treated with Folic Acid] affects the expression of BCL2 protein; Vitamin E inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased expression of BCL2 protein]

PMID:15566391 PMID:16933212 PMID:22020378 PMID:27353299 PMID:30935902 More...

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

multiple interactions
increases expression

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BCL2L1 mRNA
Vitamin E results in increased expression of BCL2L1 mRNA

PMID:11444866 PMID:19244175

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

BCL6, transcription repressor

decreases expression

Vitamin E results in decreased expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

BCL2-associated transcription factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of BCLAF1 mRNA
Vitamin E results in decreased expression of BCLAF1 mRNA

NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832

G

beta-carotene oxygenase 1

multiple interactions

Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]

NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101

G

beclin 1

multiple interactions
decreases expression

Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 mRNA]; Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 protein]
Vitamin E results in decreased expression of BECN1 protein

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

bone gamma-carboxyglutamate protein

multiple interactions

Vitamin E inhibits the reaction [Doxorubicin results in increased expression of BGLAP protein]

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

BICD cargo adaptor 1

decreases expression
multiple interactions

Vitamin E results in decreased expression of BICD1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of BICD1 mRNA

NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434

G

BICD cargo adaptor 2

decreases expression

Vitamin E results in decreased expression of BICD2 mRNA

NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889

G

bridging integrator 1

increases expression

Vitamin E results in increased expression of BIN1 mRNA

NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263

G

baculoviral IAP repeat-containing 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNA
Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BIRC2 protein]

PMID:11444866 PMID:15566391

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 3

multiple interactions

Vitamin E inhibits the reaction [cinnamaldehyde results in decreased expression of BIRC3 protein]

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

multiple interactions

Vitamin E inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

basophilic leukemia expressed protein BLES03

increases expression

Vitamin E results in increased expression of C11ORF68 mRNA

NCBI chr 1:202,734,555...202,736,809
Ensembl chr 1:202,734,555...202,736,804

G

bridge-like lipid transfer protein family member 2

increases expression

Vitamin E results in increased expression of BLTP2 mRNA

NCBI chr10:63,155,999...63,185,213
Ensembl chr10:63,156,044...63,191,141

G

bridge-like lipid transfer protein family member 3B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BLTP3B mRNA
Vitamin E results in decreased expression of BLTP3B mRNA

NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720

G

biliverdin reductase A

increases expression

Vitamin E results in increased expression of BLVRA mRNA

NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033

G

BMP-2 inducible kinase

decreases expression

Vitamin E results in decreased expression of BMP2K mRNA

NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134

G

bone morphogenetic protein 4

increases expression

Vitamin E results in increased expression of BMP4 mRNA

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bromodomain PHD finger transcription factor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BPTF mRNA
Vitamin E results in decreased expression of BPTF mRNA

NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769

G

bromodomain containing 2

multiple interactions
decreases expression
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA
Vitamin E results in decreased expression of BRD2 mRNA
Vitamin E results in increased expression of BRD2 mRNA

NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388

G

BRF2, RNA polymerase III transcription initiation factor subunit

increases expression

Vitamin E results in increased expression of BRF2 mRNA

NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059

G

BRMS1, transcriptional repressor and anoikis regulator

increases expression

Vitamin E results in increased expression of BRMS1 mRNA

NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028

G

BSCL2 lipid droplet biogenesis associated, seipin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of BSCL2 mRNA
Vitamin E results in increased expression of BSCL2 mRNA

NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421

G

bone marrow stromal cell antigen 2

increases expression

Vitamin E results in increased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

complement C1s

increases expression

Vitamin E results in increased expression of C1S mRNA

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

G

similar to human chromosome 2 open reading frame 42

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of C2ORF42 mRNA
Vitamin E results in decreased expression of C2ORF42 mRNA

NCBI chr 4:118,887,688...118,916,808
Ensembl chr 4:118,888,112...118,916,936

G

similar to human chromosome 1 open reading frame 216

increases expression

Vitamin E results in increased expression of C1ORF216 mRNA

NCBI chr 5:138,900,045...138,905,267
Ensembl chr 5:138,900,581...138,905,273

G

similar to human chromosome 1 open reading frame 50

decreases expression
multiple interactions

Vitamin E results in decreased expression of C1ORF50 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of C1ORF50 mRNA

NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762

G

similar to human chromosome 8 open reading frame 33

increases expression

Vitamin E results in increased expression of C8ORF33 mRNA

NCBI chr 7:108,682,122...108,684,372
Ensembl chr 7:108,682,176...108,684,358

G

caspase activity and apoptosis inhibitor 1

decreases expression

Vitamin E results in decreased expression of CAAP1 mRNA

NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314

G

calcium binding protein 39

increases expression

Vitamin E results in increased expression of MO25 mRNA

NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544

G

caldesmon 1

decreases expression

Vitamin E results in decreased expression of CALD1 mRNA

NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932

G

calmodulin 3

increases expression

Vitamin E results in increased expression of CALM3 mRNA

NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207

G

calreticulin

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CALR mRNA
Vitamin E results in decreased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

calumenin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CALU mRNA
Vitamin E results in increased expression of CALU mRNA

NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593

G

calcium/calmodulin-dependent protein kinase II beta

increases expression

Vitamin E results in increased expression of CAMK2B mRNA

NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994

G

calcium/calmodulin-dependent protein kinase II gamma

decreases expression

Vitamin E results in decreased expression of CAMK2G mRNA

NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050

G

cyclase associated actin cytoskeleton regulatory protein 1

increases expression

Vitamin E results in increased expression of CAP1 mRNA

NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769

G

capping actin protein, gelsolin like

increases expression

Vitamin E results in increased expression of CAPG mRNA

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

calpain 7

decreases expression

Vitamin E results in decreased expression of CAPN7 mRNA

NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905

G

calpain, small subunit 1

increases expression

Vitamin E results in increased expression of CAPNS1 mRNA

NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795

G

caprin family member 2

decreases expression

Vitamin E results in decreased expression of CAPRIN2 mRNA

NCBI chr 4:181,806,105...181,860,754
Ensembl chr 4:181,806,575...181,860,830

G

capping actin protein of muscle Z-line subunit beta

increases expression

Vitamin E results in increased expression of CAPZB mRNA

NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409

G

carbonic anhydrase 3

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CA3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

CASC3 exon junction complex subunit

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MLN51 mRNA
Vitamin E results in increased expression of MLN51 mRNA

NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966

G

caspase 3

multiple interactions
increases expression

Vitamin E inhibits the reaction [bioallethrin results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [cinnamaldehyde results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; Vitamin E inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased activity of CASP3 protein]
Vitamin E results in increased expression of CASP3 mRNA
Vitamin E inhibits the reaction [titanium dioxide results in increased activity of CASP3 protein]
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [Acrylamide results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]; Vitamin E inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [Doxorubicin results in decreased expression of CASP3 mRNA]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Tramadol results in increased expression of CASP3 protein]

PMID:12117551 PMID:15566391 PMID:16054126 PMID:16973328 PMID:21628957 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases expression
multiple interactions

Vitamin E results in increased expression of CASP9 mRNA
Vitamin E inhibits the reaction [bioallethrin results in increased cleavage of CASP9 protein]
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]

PMID:16973328 PMID:19244175 PMID:21628957 PMID:27353299 PMID:35511042

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions
increases expression
decreases activity
affects expression

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; Vitamin E inhibits the reaction [Aluminum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]
Vitamin E results in increased expression of CAT protein
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] results in increased activity of CAT protein; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; [Vitamin E co-treated with Quercetin] inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; [Vitamin E co-treated with Sodium Selenite] inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; [Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]] which affects the abundance of Reactive Oxygen Species; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; Ginkgo biloba extract promotes the reaction [Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]; Vitamin E inhibits the reaction [Atrazine results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Carbofuran results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Food Additives affects the activity of CAT protein]; Vitamin E inhibits the reaction [Formaldehyde results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Hexachlorobenzene results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Methoxychlor results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Petroleum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of CAT protein]; Vitamin E promotes the reaction [Ginkgo biloba extract inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]
Vitamin E results in decreased activity of CAT protein
[Vitamin E co-treated with coenzyme Q10] inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [fipronil results in decreased activity of CAT protein]
Vitamin E affects the expression of CAT protein

PMID:11597945 PMID:11834209 PMID:11955947 PMID:12355564 PMID:14535831 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

multiple interactions

Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAV1 protein]
Vitamin E inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of CAV1 protein]

PMID:12134086 PMID:35349355

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

caveolae associated protein 1

multiple interactions
increases expression

Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAVIN1 protein]
Vitamin E results in increased expression of CAVIN1 mRNA

PMID:19244175 PMID:21705337

NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120

G

caveolae associated protein 3

increases expression

Vitamin E results in increased expression of CAVIN3 mRNA

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

Cbl proto-oncogene B

decreases expression

Vitamin E results in decreased expression of CBLB mRNA

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

G

chromobox 5

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CBX5 mRNA
Vitamin E results in decreased expression of CBX5 mRNA

NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022

G

chromobox 6

increases expression

Vitamin E results in increased expression of CBX6 mRNA

NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091

G

chromobox 7

increases expression

Vitamin E results in increased expression of CBX7 mRNA

NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973

G

chibby 1, beta catenin antagonist

increases expression

Vitamin E results in increased expression of CBY1 mRNA

NCBI chr 7:111,216,835...111,223,305

G

coiled-coil domain containing 85B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DIPA mRNA
Vitamin E results in increased expression of DIPA mRNA

NCBI chr 1:202,763,645...202,764,660
Ensembl chr 1:202,763,631...202,764,703

G

coiled-coil alpha-helical rod protein 1

increases expression

Vitamin E results in increased expression of CCHCR1 mRNA

NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308

G

C-C motif chemokine ligand 2

multiple interactions
increases expression

alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 5

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cyclin D1

increases expression
multiple interactions
affects expression

Vitamin E results in increased expression of CCND1 mRNA
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]
Vitamin E affects the expression of CCND1 mRNA; Vitamin E affects the expression of CCND1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CCND1 mRNA

PMID:11444866 PMID:16298738 PMID:19244175 PMID:30935902

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

increases expression

Vitamin E results in increased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin D3

affects expression

Vitamin E affects the expression of CCND3 mRNA

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

affects expression

Vitamin E affects the expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin L1

decreases expression

Vitamin E results in decreased expression of CCNL1 mRNA

NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368

G

cell cycle progression 1

decreases expression

Vitamin E results in decreased expression of CPR8 mRNA

NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430

G

copper chaperone for superoxide dismutase

increases expression

Vitamin E results in increased expression of CCS mRNA

NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915

G

Cd2 (cytoplasmic tail) binding protein 2

increases expression

Vitamin E results in increased expression of CD2BP2 mRNA

NCBI chr 1:181,809,399...181,815,269
Ensembl chr 1:181,809,406...181,813,448

G

CD44 molecule

decreases expression

Vitamin E results in decreased expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

Cd63 molecule

increases expression

Vitamin E results in increased expression of CD63 mRNA

NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178

G

CD86 molecule

multiple interactions

Vitamin E inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Ethylmercuric Chloride results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Thimerosal results in increased expression of CD86 protein]

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

CD99 molecule (Xg blood group)

increases expression

Vitamin E results in increased expression of CD99 mRNA

NCBI chr20:54,418,239...54,422,882

G

cell division cycle 14B

decreases expression

Vitamin E results in decreased expression of CDC14B mRNA

NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235

G

cell division cycle 16

decreases expression

Vitamin E results in decreased expression of CDC16 mRNA

NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550

G

cell division cycle 25B

increases expression

Vitamin E results in increased expression of CDC25B mRNA

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

G

cell division cycle 27

decreases expression

Vitamin E results in decreased expression of CDC27 mRNA

NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736

G

CDC42 binding protein kinase alpha

multiple interactions
increases expression
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CDC42BPA mRNA
Vitamin E results in increased expression of CDC42BPA mRNA
Vitamin E results in decreased expression of CDC42BPA mRNA

NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732

G

cadherin 2

multiple interactions

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein]

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cadherin 3

increases expression

Vitamin E results in increased expression of CDH3 mRNA

NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084

G

cyclin-dependent kinase 10

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of CDK10 mRNA

NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078

G

cyclin-dependent kinase 13

decreases expression

Vitamin E results in decreased expression of CDK13 mRNA

NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721

G

cyclin-dependent kinase 4

increases expression

Vitamin E results in increased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

affects expression
multiple interactions

Vitamin E affects the expression of CDKN1A mRNA
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CDKN1A protein]

PMID:16298738 PMID:30935902

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression

Vitamin E results in increased expression of CDKN1B protein

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

CDP-diacylglycerol synthase 1

decreases expression

Vitamin E results in decreased expression of CDS1 mRNA

NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681

G

CCAAT/enhancer binding protein alpha

multiple interactions

Vitamin E inhibits the reaction [Ethanol results in decreased activity of CEBPA protein]; Vitamin E inhibits the reaction [Ethanol results in decreased expression of CEBPA protein]

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein beta

increases response to substance

CEBPB results in increased susceptibility to Vitamin E

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

centrosomal protein 164

increases expression

Vitamin E results in increased expression of CEP164 mRNA

NCBI chr 8:46,070,901...46,134,511
Ensembl chr 8:46,071,076...46,134,336

G

centrosomal protein 170

decreases expression

Vitamin E results in decreased expression of CEP170 mRNA

NCBI chr13:88,669,672...88,754,011
Ensembl chr13:88,670,358...88,732,226

G

centrosomal protein 290

decreases expression

Vitamin E results in decreased expression of CEP290 mRNA

NCBI chr 7:35,310,071...35,399,388
Ensembl chr 7:35,310,199...35,399,392

G

centrosomal protein 350

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNA
Vitamin E results in decreased expression of CEP350 mRNA

NCBI chr13:68,023,327...68,164,478
Ensembl chr13:68,026,891...68,165,214

G

centrosomal protein 57

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CEP57 mRNA
Vitamin E results in decreased expression of CEP57 mRNA

NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:10,669,590...10,689,249

G

centrosomal protein 97

decreases expression

Vitamin E results in decreased expression of CEP97 mRNA

NCBI chr11:44,683,503...44,711,471
Ensembl chr11:44,683,506...44,711,471

G

ceramide kinase

increases expression

Vitamin E results in increased expression of CERK mRNA

NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759

G

ceramide transporter 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CERT1 mRNA
Vitamin E results in decreased expression of CERT1 mRNA

NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074

G

carboxylesterase 1D

increases expression

Vitamin E results in increased expression of CES1 mRNA

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

CASP8 and FADD-like apoptosis regulator

increases expression

Vitamin E results in increased expression of CFLAR mRNA

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

G

chromodomain helicase DNA binding protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CHD1 mRNA
Vitamin E results in decreased expression of CHD1 mRNA

NCBI chr 1:56,661,743...56,729,119
Ensembl chr 1:56,664,054...56,728,125

G

cysteine and histidine rich domain containing 1

decreases expression

Vitamin E results in decreased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

chondroitin polymerizing factor

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of CHPF mRNA

NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878

G

carbohydrate sulfotransferase 3

increases expression

Vitamin E results in increased expression of CHST3 mRNA

NCBI chr20:28,114,386...28,152,046
Ensembl chr20:28,114,404...28,121,807

G

carbohydrate sulfotransferase 5

increases expression

Vitamin E results in increased expression of CHST6 mRNA

NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064

G

cytosolic iron-sulfur assembly component 2B

increases expression

Vitamin E results in increased expression of CIAO2B mRNA

NCBI chr19:344,194...346,068
Ensembl chr19:344,203...346,068

G

calcium and integrin binding family member 2

increases expression

Vitamin E results in increased expression of CIB2 mRNA

NCBI chr 8:54,930,265...54,947,157

G

cold inducible RNA binding protein

increases expression

Vitamin E results in increased expression of CIRBP mRNA

NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818

G

cytoskeleton associated protein 2

decreases expression

Vitamin E results in decreased expression of CKAP2 mRNA

NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913

G

creatine kinase B

increases expression

Vitamin E results in increased expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

creatine kinase, M-type

multiple interactions

Vitamin E inhibits the reaction [Diazinon results in increased activity of CKM protein]

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

chloride channel CLIC-like 1

decreases expression

Vitamin E results in decreased expression of CLCC1 mRNA

NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913

G

chloride voltage-gated channel 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CLCN3 mRNA
Vitamin E results in decreased expression of CLCN3 mRNA

NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119

G

claudin 4

multiple interactions

Vitamin E inhibits the reaction [phoxim results in decreased expression of CLDN4 mRNA]

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

C-type lectin domain family 3, member B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TNA mRNA
Vitamin E results in increased expression of TNA mRNA

NCBI chr 8:122,810,120...122,815,837
Ensembl chr 8:122,810,149...122,815,835

G

chloride intracellular channel 1

increases expression

Vitamin E results in increased expression of CLIC1 mRNA

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

CAP-GLY domain containing linker protein 1

decreases expression

Vitamin E results in decreased expression of CLIP1 mRNA

NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of CLN3 mRNA
Vitamin E results in increased expression of CLN3 mRNA

NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434

G

clathrin, light chain B

increases expression

Vitamin E results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

clusterin

multiple interactions
increases expression

Vitamin E inhibits the reaction [Estradiol results in increased expression of CLU protein]
Vitamin E results in increased expression of CLU mRNA

PMID:9037392 PMID:19244175

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

cap methyltransferase 1

increases expression

Vitamin E results in increased expression of CMTR1 mRNA

NCBI chr20:7,722,729...7,782,579
Ensembl chr20:7,709,713...7,766,302

G

cyclic nucleotide gated channel subunit beta 1

decreases expression

Vitamin E results in decreased expression of CNGB1 mRNA

NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173

G

calponin 1

increases expression

Vitamin E results in increased expression of CNN1 mRNA

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

canopy FGF signaling regulator 2

decreases expression

Vitamin E results in decreased expression of CNPY2 mRNA

NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519

G

canopy FGF signaling regulator 3

increases expression

Vitamin E results in increased expression of CNPY3 mRNA

NCBI chr 9:14,233,478...14,247,847
Ensembl chr 9:14,233,428...14,247,831

G

component of oligomeric golgi complex 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of COG4 mRNA

NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796

G

collagen type XVIII alpha 1 chain

increases expression

Vitamin E results in increased expression of COL18A1 mRNA

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 1 chain

multiple interactions

[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

multiple interactions

Vitamin E inhibits the reaction [CYP2E1 protein results in increased expression of COL1A2 mRNA]

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type IV alpha 1 chain

increases expression

Vitamin E results in increased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type IV alpha 3 chain

decreases expression

Vitamin E results in decreased expression of COL4A3 mRNA

NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895

G

collagen type VI alpha 2 chain

increases expression

Vitamin E results in increased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen type VI alpha 3 chain

increases expression

Vitamin E results in increased expression of COL6A3 mRNA

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

collagen beta(1-O)galactosyltransferase 2

increases expression

Vitamin E results in increased expression of COLGALT2 mRNA

NCBI chr13:64,523,641...64,628,295
Ensembl chr13:64,523,658...64,627,549

G

COMM domain containing 3

decreases expression

Vitamin E results in decreased expression of COMMD3 mRNA

NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177

G

COPI coat complex subunit epsilon

increases expression

Vitamin E results in increased expression of COPE mRNA

NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907

G

COP9 signalosome subunit 6

increases expression

Vitamin E results in increased expression of COPS6 mRNA

NCBI chr12:17,038,979...17,041,818
Ensembl chr12:17,038,979...17,046,371

G

COPI coat complex subunit zeta 2

increases expression

Vitamin E results in increased expression of COPZ2 mRNA

NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514

G

coenzyme Q9

increases expression

Vitamin E results in increased expression of COQ9 mRNA

NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949

G

cytochrome c oxidase subunit 6A1

decreases expression

Vitamin E results in decreased expression of COX6A1 mRNA

NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041

G

carboxypeptidase M

decreases expression

Vitamin E results in decreased expression of CPM mRNA

NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220

G

copine 1

increases expression

Vitamin E results in increased expression of CPNE1 mRNA

NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636

G

cleavage and polyadenylation specific factor 1

increases expression

Vitamin E results in increased expression of CPSF1 mRNA

NCBI chr 7:108,319,429...108,330,018
Ensembl chr 7:108,319,434...108,329,934

G

complement C3b/C4b receptor 1 like

multiple interactions

Vitamin E inhibits the reaction [Endosulfan results in decreased expression of CR1L mRNA]

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

G

complement C3d receptor 2

multiple interactions

Vitamin E inhibits the reaction [Endosulfan results in decreased expression of CR2 mRNA]; Vitamin E inhibits the reaction [Endosulfan results in decreased expression of CR2 protein]

NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235

G

cAMP responsive element binding protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CREB1 mRNA
Vitamin E results in decreased expression of CREB1 mRNA

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element binding protein 3

increases expression

Vitamin E results in increased expression of CREB3 mRNA

NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390

G

CREB binding protein

decreases expression

Vitamin E results in decreased expression of CREBBP mRNA

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

C-reactive protein

multiple interactions
decreases expression

[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid] results in decreased expression of CRP protein
Vitamin E inhibits the reaction [titanium dioxide results in increased expression of CRP protein]
Vitamin E results in decreased expression of CRP protein

PMID:16517955 PMID:17237316 PMID:20370442 PMID:30626778

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

crystallin beta-gamma domain containing 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of CRYBG2 mRNA
Vitamin E results in increased expression of CRYBG2 mRNA

NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666

G

casein kinase 1, alpha 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CSNK1A1 mRNA
Vitamin E results in decreased expression of CSNK1A1 mRNA

NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271

G

casein kinase 1, delta

decreases expression

Vitamin E results in decreased expression of CSNK1D mRNA

NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614

G

casein kinase 1, epsilon

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of CSNK1E mRNA

NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794

G

casein kinase 1, gamma 2

decreases expression

Vitamin E results in decreased expression of CSNK1G2 mRNA

NCBI chr 7:9,076,739...9,095,082
Ensembl chr 7:9,076,740...9,095,052

G

casein kinase 1, gamma 3

decreases expression

Vitamin E results in decreased expression of CSNK1G3 mRNA

NCBI chr18:47,299,547...47,386,538
Ensembl chr18:47,299,579...47,386,535

G

casein kinase 2 alpha 1

decreases expression

Vitamin E results in decreased expression of CSNK2A1 mRNA

NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696

G

casein kinase 2 beta

increases expression

Vitamin E results in increased expression of CSNK2B mRNA

NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133

G

chondroitin sulfate proteoglycan 4

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of CSPG4 mRNA
Vitamin E results in increased expression of CSPG4 mRNA

NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010

G

centrosome and spindle pole associated protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CSPP1 mRNA
Vitamin E results in decreased expression of CSPP1 mRNA

NCBI chr 5:9,077,161...9,192,402
Ensembl chr 5:9,077,161...9,193,377

G

cysteine and glycine-rich protein 1

increases expression

Vitamin E results in increased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cystatin C

increases expression

Vitamin E results in increased expression of CST3 mRNA

NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822

G

C-terminal binding protein 1

decreases expression

Vitamin E results in decreased expression of CTBP1 mRNA

NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821

G

C-terminal binding protein 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CTBP2 mRNA
Vitamin E results in decreased expression of CTBP2 mRNA

NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222

G

CTD nuclear envelope phosphatase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CTDNEP1 mRNA
Vitamin E results in increased expression of CTDNEP1 mRNA

NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781

G

CTD small phosphatase like

increases expression

Vitamin E results in increased expression of CTDSPL mRNA

NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:118,642,672...118,767,117

G

cardiotrophin 1

decreases expression

Vitamin E results in decreased expression of CTF1 protein

NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335

G

catenin beta 1

multiple interactions

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the localization of CTNNB1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein]
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CTNNB1 protein]

PMID:29940330 PMID:30935902

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

catenin, beta like 1

increases expression

Vitamin E results in increased expression of CTNNBL1 mRNA

NCBI chr 3:146,387,940...146,548,987
Ensembl chr 3:146,387,889...146,548,987

G

cortactin

decreases expression

Vitamin E results in decreased expression of CTTN mRNA

NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164

G

CUE domain containing 2

increases expression

Vitamin E results in increased expression of CUEDC2 mRNA

NCBI chr 1:245,192,057...245,200,594
Ensembl chr 1:245,192,063...245,200,339

G

cullin 3

decreases expression

Vitamin E results in decreased expression of CUL3 mRNA

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

G

cullin 4A

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CUL4A mRNA
Vitamin E results in increased expression of CUL4A mRNA

NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330

G

cutC copper transporter

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CUTC mRNA
Vitamin E results in decreased expression of CUTC mRNA

NCBI chr 1:242,622,281...242,637,048
Ensembl chr 1:242,622,276...242,637,047

G

cut-like homeobox 1

decreases expression

Vitamin E results in decreased expression of CUX1 mRNA

NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866

G

cell wall biogenesis 43 C-terminal homolog

decreases expression

Vitamin E results in decreased expression of CWH43 mRNA

NCBI chr14:34,754,279...34,800,530
Ensembl chr14:34,754,289...34,800,814

G

C-X-C motif chemokine receptor 1

increases expression

Vitamin E results in increased expression of CXCR1 mRNA

NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084

G

cytochrome b-245 alpha chain

decreases expression

Vitamin E results in decreased expression of CYBA mRNA

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome c, somatic

multiple interactions

Vitamin E inhibits the reaction [cinnamaldehyde affects the localization of CYCS protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate affects the localization of CYCS protein]
Vitamin E inhibits the reaction [Diazinon affects the localization of CYCS protein]

PMID:15566391 PMID:16054126 PMID:23523949

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytoplasmic FMR1 interacting protein 1

increases expression

Vitamin E results in increased expression of CYFIP1 mRNA

NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions

Vitamin E inhibits the reaction [acetamiprid results in decreased expression of CYP11A mRNA]; Vitamin E inhibits the reaction [acetamiprid results in decreased expression of CYP11A protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CYP11A1 protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 mRNA]

PMID:16298753 PMID:17280759 PMID:28395332

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 11, subfamily b, polypeptide 3

multiple interactions
decreases expression

Vitamin E inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Vitamin E promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein]
Vitamin E results in decreased expression of CYP11B2 mRNA

PMID:10822027 PMID:28923436

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases expression
multiple interactions

Vitamin E results in decreased expression of CYP19A1 mRNA
Vitamin E inhibits the reaction [Doxorubicin results in decreased expression of CYP19A1 mRNA]

PMID:15084515 PMID:32810592

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

Vitamin E results in increased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

affects expression

Vitamin E inhibits the reaction [nitroglycerine decreases Cyp1a2 protein expression in rat heart]

RGD

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Paraquat] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Vitamin E inhibits the reaction [CYP2E1 protein results in increased expression of COL1A2 mRNA]
Vitamin E inhibits the reaction [decamethrin results in increased expression of CYP2E1 mRNA]

PMID:10498651 PMID:22486562 PMID:25439240

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases expression

Vitamin E results in decreased expression of CYP3A4 mRNA

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

decreases expression

Vitamin E results in decreased expression of CYP3A5 mRNA

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

dishevelled associated activator of morphogenesis 1

decreases expression

Vitamin E results in decreased expression of DAAM1 mRNA

NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114

G

dishevelled associated activator of morphogenesis 2

increases expression

Vitamin E results in increased expression of DAAM2 mRNA

NCBI chr 9:11,428,913...11,546,982
Ensembl chr 9:11,428,724...11,545,497

G

dishevelled-binding antagonist of beta-catenin 1

decreases expression

Vitamin E results in decreased expression of DACT1 mRNA

NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906

G

defender against cell death 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of DAD1 mRNA

NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347

G

death-associated protein kinase 3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DAPK3 mRNA
Vitamin E results in increased expression of DAPK3 mRNA

NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558

G

DDB1 and CUL4 associated factor 8

increases expression

Vitamin E results in increased expression of DCAF8 mRNA

NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726

G

decorin

increases expression

Vitamin E results in increased expression of DCN mRNA

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

dynactin subunit 3

increases expression

Vitamin E results in increased expression of DCTN3 mRNA

NCBI chr 5:56,881,085...56,889,041
Ensembl chr 5:56,881,085...56,889,102

G

DDAH family member 2, ADMA-independent

increases expression

Vitamin E results in increased expression of DDAH2 mRNA

NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511

G

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

increases expression

Vitamin E results in increased expression of DDOST mRNA

NCBI chr 5:150,522,297...150,529,413
Ensembl chr 5:150,522,242...150,529,413

G

DEAD-box helicase 17

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of DDX17 mRNA
Vitamin E results in decreased expression of DDX17 mRNA

NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193

G

DEAD-box helicase 18

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DDX18 mRNA
Vitamin E results in decreased expression of DDX18 mRNA

NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161

G

DEAD-box helicase 24

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DDX24 mRNA
Vitamin E results in decreased expression of DDX24 mRNA

NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927

G

DExD-box helicase 39B

increases expression
decreases expression

Vitamin E results in increased expression of DDX39B mRNA
Vitamin E results in decreased expression of DDX39B mRNA

NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996

G

DEAD-box helicase 41

increases expression
multiple interactions

Vitamin E results in increased expression of DDX41 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of DDX41 mRNA

NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415

G

death effector domain-containing

increases expression

Vitamin E results in increased expression of DEDD mRNA

NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332

G

DENN domain containing 1B

decreases expression

Vitamin E results in decreased expression of DENND1B mRNA

NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601

G

DENN domain containing 2B

increases expression

Vitamin E results in increased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

DENN domain containing 2D

decreases expression

Vitamin E results in decreased expression of DENND2D mRNA

NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270

G

DENN domain containing 4A

decreases expression

Vitamin E results in decreased expression of DENND4A mRNA

NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330

G

DENN domain containing 5A

increases expression

Vitamin E results in increased expression of DENND5A mRNA

NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316

G

desmin

increases expression

Vitamin E results in increased expression of DES mRNA

NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699

G

DGCR8 microprocessor complex subunit

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of DGCR8 mRNA

NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242

G

7-dehydrocholesterol reductase

affects expression

Vitamin E affects the expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dihydroorotate dehydrogenase (quinone)

decreases expression

Vitamin E results in decreased expression of DHODH mRNA

NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654

G

deoxyhypusine synthase

increases expression
multiple interactions

Vitamin E results in increased expression of DHPS mRNA
[Selenium co-treated with Vitamin E] results in increased expression of DHPS mRNA

NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881

G

dehydrogenase/reductase 1

increases expression

Vitamin E results in increased expression of DHRS1 mRNA

NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838

G

dehydrogenase/reductase 4

increases expression

Vitamin E results in increased expression of DHRS4 mRNA

NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127

G

DExH-box helicase 9

decreases expression

Vitamin E results in decreased expression of DHX9 mRNA

NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069

G

diablo, IAP-binding mitochondrial protein

multiple interactions

Vitamin E inhibits the reaction [cinnamaldehyde affects the localization of DIABLO protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate affects the localization of DIABLO protein]

PMID:15566391 PMID:16054126

NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387

G

dicer 1 ribonuclease III

decreases expression

Vitamin E results in decreased expression of DICER1 mRNA

NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965

G

iodothyronine deiodinase 2

increases expression

Vitamin E results in increased expression of DIO2 mRNA

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

dihydrolipoamide S-succinyltransferase

increases expression

Vitamin E results in increased expression of DLST mRNA

NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296

G

cyclin D binding myb-like transcription factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of DMTF1 mRNA
Vitamin E results in decreased expression of DMTF1 mRNA

NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967

G

DnaJ heat shock protein family (Hsp40) member A3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJA3 mRNA
Vitamin E results in decreased expression of DNAJA3 mRNA

NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161

G

DnaJ heat shock protein family (Hsp40) member B4

decreases expression

Vitamin E results in decreased expression of DNAJB4 mRNA

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member C2

decreases expression
multiple interactions

Vitamin E results in decreased expression of DNAJC2 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of DNAJC2 mRNA

NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

Vitamin E results in decreased expression of DNAJC3 mRNA

NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181

G

DnaJ heat shock protein family (Hsp40) member C7

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJC7 mRNA
Vitamin E results in increased expression of DNAJC7 mRNA

NCBI chr10:85,518,637...85,555,079
Ensembl chr10:85,518,621...85,555,575

G

DNA methyltransferase 1

increases expression

Vitamin E results in increased expression of DNMT1 mRNA

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

decreases expression

Vitamin E results in decreased expression of DNMT3A mRNA

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

increases expression

Vitamin E results in increased expression of DNPH1 mRNA

NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022

G

dedicator of cyto-kinesis 1

decreases expression

Vitamin E results in decreased expression of DOCK1 mRNA

NCBI chr 1:189,467,143...189,983,777
Ensembl chr 1:189,467,143...189,983,768

G

deoxyhypusine hydroxylase

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of DOHH mRNA
Vitamin E results in increased expression of DOHH mRNA

NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289

G

docking protein 1

increases expression

Vitamin E results in increased expression of DOK1 mRNA

NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465

G

dermatopontin

increases expression

Vitamin E results in increased expression of DPT mRNA

NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639

G

dihydropyrimidinase-like 3

increases expression

Vitamin E results in increased expression of DPYSL3 mRNA

NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157

G

down-regulator of transcription 1

decreases expression

Vitamin E results in decreased expression of DR1 mRNA

NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638

G

developmentally regulated GTP binding protein 2

increases expression

Vitamin E results in increased expression of DRG2 mRNA

NCBI chr10:45,255,512...45,269,971
Ensembl chr10:45,255,507...45,269,969

G

desmocollin 2

decreases expression
multiple interactions

Vitamin E results in decreased expression of DSC2 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

decapping exoribonuclease

increases expression

Vitamin E results in increased expression of DXO mRNA

NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494

G

dynein cytoplasmic 1 heavy chain 1

increases expression

Vitamin E results in increased expression of DYNC1H1 mRNA

NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883

G

E2F transcription factor 6

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of E2F6 mRNA
Vitamin E results in decreased expression of E2F6 mRNA

NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683

G

enoyl CoA hydratase domain containing 2

decreases expression

Vitamin E results in decreased expression of ECHDC2 mRNA

NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859

G

ECSIT signaling integrator

increases expression
multiple interactions

Vitamin E results in increased expression of ECSIT mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ECSIT mRNA

NCBI chr 8:20,605,583...20,618,453
Ensembl chr 8:20,605,583...20,618,390

G

ectodysplasin-A

decreases expression

Vitamin E results in decreased expression of EDA mRNA

NCBI chr X:65,078,454...65,480,172
Ensembl chr X:65,078,673...65,480,172

G

ER degradation enhancing alpha-mannosidase like protein 3

decreases expression

Vitamin E results in decreased expression of EDEM3 mRNA

NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523

G

endothelial differentiation-related factor 1

increases expression

Vitamin E results in increased expression of EDF1 mRNA

NCBI chr 3:8,377,058...8,381,363
Ensembl chr 3:8,366,613...8,381,363

G

endothelin receptor type A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of EDNRA mRNA
Vitamin E results in decreased expression of EDNRA mRNA

NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049

G

eukaryotic translation elongation factor 1 alpha 2

increases expression
multiple interactions

Vitamin E results in increased expression of EEF1A2 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of EEF1A2 mRNA

NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071

G

eukaryotic translation elongation factor 1 delta

increases expression

Vitamin E results in increased expression of EEF1D mRNA

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

eukaryotic translation elongation factor 2

multiple interactions
increases expression

Vitamin E analog inhibits the reaction [cumene hydroperoxide results in decreased expression of EEF2 protein]
Vitamin E analog results in increased expression of EEF2 protein

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

EF-hand calcium binding domain 14

increases expression

Vitamin E results in increased expression of EFCAB14 mRNA

NCBI chr 5:129,218,139...129,258,628
Ensembl chr 5:129,218,424...129,258,625

G

EGF containing fibulin extracellular matrix protein 2

increases expression

Vitamin E results in increased expression of EFEMP2 mRNA

NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414

G

EF-hand domain containing 1

decreases expression

Vitamin E results in decreased expression of EFHC1 mRNA

NCBI chr 9:23,375,815...23,414,283
Ensembl chr 9:23,375,840...23,414,283

G

EF-hand domain family, member D2

increases expression

Vitamin E results in increased expression of EFHD2 mRNA

NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980

G

epidermal growth factor receptor

decreases expression

Vitamin E results in decreased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

egl-9 family hypoxia-inducible factor 2

increases expression

Vitamin E results in increased expression of EGLN2 mRNA

NCBI chr 1:82,451,554...82,459,809
Ensembl chr 1:82,451,555...82,459,751

G

early growth response 1

decreases expression
multiple interactions

Vitamin E results in decreased expression of EGR1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of EGR1 mRNA

PMID:11444866 PMID:19244175

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

EH domain binding protein 1

decreases expression

Vitamin E results in decreased expression of EHBP1 mRNA

NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332

G

EH-domain containing 2

increases expression

Vitamin E results in increased expression of EHD2 mRNA

NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783

G

eukaryotic translation initiation factor 2-alpha kinase 2

decreases expression

Vitamin E results in decreased expression of EIF2AK2 mRNA

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2B subunit beta

increases expression

Vitamin E results in increased expression of EIF2B2 mRNA

NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353

G

eukaryotic translation initiation factor 3, subunit A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of EIF3A mRNA
Vitamin E results in decreased expression of EIF3A mRNA

NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976

G

eukaryotic translation initiation factor 3, subunit B

increases expression

Vitamin E results in increased expression of EIF3B mRNA

NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886

G

eukaryotic translation initiation factor 3, subunit K

increases expression

Vitamin E results in increased expression of EIF3K mRNA

NCBI chr 1:84,260,127...84,270,051
Ensembl chr 1:84,259,673...84,270,302

G

eukaryotic translation initiation factor 4A1

increases expression

Vitamin E results in increased expression of EIF4A1 mRNA

NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858

G

eukaryotic translation initiation factor 4E binding protein 2

increases expression

Vitamin E results in increased expression of EIF4EBP2 mRNA

NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946

G

eukaryotic translation initiation factor 4 gamma 1

multiple interactions
increases expression
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EIF4G1 mRNA
Vitamin E results in increased expression of EIF4G1 mRNA
Vitamin E results in decreased expression of EIF4G1 mRNA

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

eukaryotic translation initiation factor 5

decreases expression

Vitamin E results in decreased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

eukaryotic translation initiation factor 5A

multiple interactions
increases expression
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EIF5A mRNA
Vitamin E results in increased expression of EIF5A mRNA
Vitamin E results in decreased expression of EIF5A mRNA

NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656

G

eukaryotic translation initiation factor 5B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of IF2 mRNA
Vitamin E results in decreased expression of IF2 mRNA

NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482

G

eukaryotic translation initiation factor 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EIF6 mRNA
Vitamin E results in increased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

E74 like ETS transcription factor 1

decreases expression

Vitamin E results in decreased expression of ELF1 mRNA

NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699

G

ETS transcription factor ELK1

increases phosphorylation

Vitamin E results in increased phosphorylation of ELK1 protein

NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713

G

elongin A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ELOA mRNA
Vitamin E results in decreased expression of ELOA mRNA

NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765

G

ER membrane protein complex subunit 6

increases expression

Vitamin E results in increased expression of EMC6 mRNA

NCBI chr10:57,794,072...57,795,671
Ensembl chr10:57,793,685...57,796,217

G

ER membrane protein complex subunit 9

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EMC9 mRNA
Vitamin E results in increased expression of EMC9 mRNA

NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098

G

elastin microfibril interfacer 1

increases expression

Vitamin E results in increased expression of EMILIN1 mRNA

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

EMAP like 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EML2 mRNA
Vitamin E results in increased expression of EML2 mRNA

NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341

G

epithelial membrane protein 3

increases expression

Vitamin E results in increased expression of EMP3 mRNA

NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988

G

EMSY transcriptional repressor, BRCA2 interacting

decreases expression

Vitamin E results in decreased expression of EMSY mRNA

NCBI chr 1:152,881,485...152,960,420
Ensembl chr 1:152,883,992...152,953,528

G

endonuclease G

increases expression

Vitamin E results in increased expression of ENDOG mRNA

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

enolase 1

increases expression

Vitamin E results in increased expression of ENO1 mRNA

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

enolase 2

increases expression

Vitamin E results in increased expression of ENO2 mRNA

NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980

G

ectonucleoside triphosphate diphosphohydrolase 1

increases expression

Vitamin E results in increased expression of ENTPD1 mRNA

NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317

G

ectonucleoside triphosphate diphosphohydrolase 5

decreases expression

Vitamin E results in decreased expression of ENTPD5 mRNA

NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530

G

erythrocyte membrane protein band 4.1-like 2

increases expression

Vitamin E results in increased expression of EPB41L2 mRNA

NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721

G

epsin 2

increases expression

Vitamin E results in increased expression of EPN2 mRNA

NCBI chr10:46,197,785...46,259,673
Ensembl chr10:46,197,785...46,259,642

G

erb-b2 receptor tyrosine kinase 2

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ERBB2 mRNA

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

Vitamin E results in increased expression of ERCC1 mRNA

NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963

G

ERCC excision repair 3, TFIIH core complex helicase subunit

increases expression

Vitamin E results in increased expression of ERCC3 mRNA

NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329

G

estrogen receptor 1

multiple interactions
affects expression

Vitamin E affects the reaction [Doxorubicin affects the expression of ESR1 mRNA]
Vitamin E affects the expression of ESR1 mRNA

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

epithelial splicing regulatory protein 2

decreases expression
multiple interactions

Vitamin E results in decreased expression of ESRP2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ESRP2 mRNA

NCBI chr19:34,034,559...34,041,726
Ensembl chr19:34,034,559...34,041,726

G

ess-2 splicing factor homolog

increases expression

Vitamin E results in increased expression of ESS2 mRNA

NCBI chr11:83,075,893...83,085,849
Ensembl chr11:83,075,925...83,084,846

G

ETS proto-oncogene 2, transcription factor

decreases expression

Vitamin E results in decreased expression of ETS2 mRNA

NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319

G

ecotropic viral integration site 5

decreases expression

Vitamin E results in decreased expression of EVI5 mRNA

NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678

G

Enah/Vasp-like

increases expression

Vitamin E results in increased expression of EVL mRNA

NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344

G

EWS RNA-binding protein 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EWSR1 mRNA
Vitamin E results in increased expression of EWSR1 mRNA

NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544

G

exocyst complex component 3

increases expression

Vitamin E results in increased expression of SEC6 mRNA

NCBI chr 1:29,091,298...29,122,056
Ensembl chr 1:29,091,294...29,122,045

G

exosome component 4

increases expression

Vitamin E results in increased expression of EXOSC4 mRNA

NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573

G

exostosin glycosyltransferase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EXT1 mRNA
Vitamin E results in increased expression of EXT1 mRNA

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

G

EYA transcriptional coactivator and phosphatase 2

increases expression

Vitamin E results in increased expression of EYA2 mRNA

NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

increases expression

Vitamin E results in increased expression of EZH1 mRNA

NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921

G

ezrin

decreases expression
multiple interactions

Vitamin E results in decreased expression of EZR mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of EZR mRNA

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor X

increases expression

Vitamin E results in increased expression of F10 mRNA

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

G

coagulation factor II, thrombin

multiple interactions

Vitamin E results in decreased expression of and results in decreased activity of F2 protein

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

coagulation factor II (thrombin) receptor

decreases expression
multiple interactions

Vitamin E results in decreased expression of F2R mRNA
[Selenium co-treated with Vitamin E] results in increased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

coagulation factor III, tissue factor

multiple interactions

Vitamin E inhibits the reaction [Copper results in increased activity of F3 protein]; Vitamin E inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; Vitamin E results in decreased expression of and results in decreased activity of F3 protein

PMID:7600656 PMID:10216089 PMID:23114885

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

fatty acid binding protein 3

increases expression

Vitamin E results in increased expression of FABP3 mRNA

NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718

G

Fas apoptotic inhibitory molecule

increases expression

Vitamin E results in increased expression of FAIM mRNA

NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562

G

family with sequence similarity 107, member A

increases expression

Vitamin E results in increased expression of FAM107A mRNA

NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396

G

FAM111 trypsin like peptidase A

decreases expression
multiple interactions

Vitamin E results in decreased expression of FAM111A mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

family with sequence similarity 149, member A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of FAM149A mRNA
Vitamin E results in decreased expression of FAM149A mRNA

NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066

G

family with sequence similarity 174 member C

decreases expression

Vitamin E results in decreased expression of FAM174C mRNA

NCBI chr 7:9,531,995...9,533,705

G

family with sequence similarity 222, member B

decreases expression

Vitamin E results in decreased expression of FAM222B mRNA

NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350

G

FAM3 metabolism regulating signaling molecule A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of FAM3A mRNA

NCBI chr X:152,166,716...152,175,327
Ensembl chr X:152,165,535...152,175,362

G

family with sequence similarity 53, member B

increases expression

Vitamin E results in increased expression of FAM53B mRNA

NCBI chr 1:187,500,061...187,591,186
Ensembl chr 1:187,500,066...187,591,186

G

family with sequence similarity 89, member B

increases expression

Vitamin E results in increased expression of FAM89B mRNA

NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367

G

phenylalanyl-tRNA synthetase subunit alpha

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of FARSA mRNA
Vitamin E results in increased expression of FARSA mRNA

NCBI chr19:23,291,409...23,300,985
Ensembl chr19:23,268,869...23,300,980

G

FAST kinase domains 3

decreases expression

Vitamin E results in decreased expression of FASTKD3 mRNA

NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973

G

FAT atypical cadherin 4

decreases expression

Vitamin E results in decreased expression of FAT4 mRNA

NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707

G

fibulin 1

increases expression

Vitamin E results in increased expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

F-box and leucine-rich repeat protein 7

increases expression

Vitamin E results in increased expression of FBXL7 mRNA

NCBI chr 2:77,139,775...77,509,223
Ensembl chr 2:77,140,826...77,509,223

G

F-box protein 17

increases expression

Vitamin E results in increased expression of FBXO17 mRNA

NCBI chr 1:84,002,276...84,024,455
Ensembl chr 1:84,002,267...84,024,453

G

F-box protein 28

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of FBXO28 mRNA

NCBI chr13:93,995,993...94,021,464
Ensembl chr13:93,995,996...94,021,464

G

F-box protein 31

increases expression

Vitamin E results in increased expression of FBXO31 mRNA

NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010

G

F-box and WD repeat domain containing 2

increases expression

Vitamin E results in increased expression of FBXW2 mRNA

NCBI chr 3:18,088,859...18,114,387
Ensembl chr 3:18,088,865...18,114,381

G

ferrochelatase

decreases expression

Vitamin E results in decreased expression of FECH mRNA

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

FERM domain containing kindlin 1

decreases expression

Vitamin E results in decreased expression of FERMT1 mRNA

NCBI chr 3:120,171,301...120,213,555
Ensembl chr 3:120,171,561...120,213,555

G

FERRY endosomal RAB5 effector complex subunit 3

decreases expression

Vitamin E results in decreased expression of FERRY3 mRNA

NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382

G

fibrinogen gamma chain

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

FGF1 intracellular binding protein

increases expression

Vitamin E results in increased expression of FIBP mRNA

NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399

G

FIG4 phosphoinositide 5-phosphatase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FIG4 mRNA
Vitamin E results in decreased expression of FIG4 mRNA

NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844

G

fission, mitochondrial 1

increases expression

Vitamin E results in increased expression of FIS1 mRNA

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FKBP prolyl isomerase 1A

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FKBP1A mRNA
Vitamin E results in increased expression of FKBP1A mRNA

NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743

G

FLII, actin remodeling protein

increases expression

Vitamin E results in increased expression of FLII mRNA

NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970

G

filamin A

increases expression

Vitamin E results in increased expression of FLNA mRNA

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

flotillin 1

increases expression

Vitamin E results in increased expression of FLOT1 mRNA

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

G

fibronectin leucine rich transmembrane protein 3

decreases expression

Vitamin E results in decreased expression of FLRT3 mRNA

NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841

G

flavin containing dimethylaniline monoxygenase 5

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of FMO5 mRNA
Vitamin E results in decreased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

formin binding protein 1

decreases expression

Vitamin E results in decreased expression of FNBP1 mRNA

NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881

G

formin binding protein 4

decreases expression

Vitamin E results in decreased expression of FNBP4 mRNA

NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079

G

folate hydrolase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FOLH1 mRNA
Vitamin E results in decreased expression of FOLH1 mRNA

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions

Vitamin E promotes the reaction [Alcohols results in increased expression of FOS mRNA]

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box A2

multiple interactions

Vitamin E inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein]
Vitamin E inhibits the reaction [nitrofen results in decreased expression of FOXA2 mRNA]

PMID:16490937 PMID:16863852

NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326

G

forkhead box E1

decreases expression

Vitamin E results in decreased expression of FOXE1 mRNA

NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835

G

forkhead box F2

decreases expression

Vitamin E results in decreased expression of FOXF2 mRNA

NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176

G

forkhead box M1

decreases expression

Vitamin E results in decreased expression of FOXM1 mRNA

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O1

decreases expression

Vitamin E results in decreased expression of FOXO1 mRNA

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

FRAT regulator of WNT signaling pathway 1

increases expression

Vitamin E results in increased expression of FRAT1 mRNA

NCBI chr 1:240,638,309...240,640,857
Ensembl chr 1:240,638,296...240,640,945

G

follicle stimulating hormone subunit beta

multiple interactions

Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of FSHB protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in increased expression of FSHB protein]; Vitamin E inhibits the reaction [cypermethrin results in decreased expression of FSHB protein]; Vitamin E inhibits the reaction [Petroleum results in increased expression of FSHB protein]; Vitamin E inhibits the reaction [Potassium Dichromate results in increased expression of FSHB protein]

PMID:17280759 PMID:20079796 PMID:24759048 PMID:25046308

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

follistatin

increases expression

Vitamin E results in increased expression of FST mRNA

NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571

G

FtsJ RNA 2'-O-methyltransferase 1

decreases expression

Vitamin E results in decreased expression of FTSJ1 mRNA

NCBI chr X:14,243,684...14,256,555
Ensembl chr X:14,244,050...14,252,030

G

Fus RNA binding protein

increases expression

Vitamin E results in increased expression of FUS mRNA

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

FMR1 autosomal homolog 1

decreases expression

Vitamin E results in decreased expression of FXR1 mRNA

NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590

G

FMR1 autosomal homolog 2

increases expression

Vitamin E results in increased expression of FXR2 mRNA

NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964

G

FXYD domain-containing ion transport regulator 6

increases expression

Vitamin E results in increased expression of FXYD6 mRNA

NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958

G

fizzy and cell division cycle 20 related 1

increases expression
multiple interactions

Vitamin E results in increased expression of FZR1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of FZR1 mRNA

NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952

G

G0/G1switch 2

increases expression

Vitamin E results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

multiple interactions

Vitamin E inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]
Vitamin E inhibits the reaction [Atrazine results in decreased activity of G6PD protein]

PMID:19635623 PMID:20136348

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

GRB2-associated binding protein 2

increases expression

Vitamin E results in increased expression of GAB2 mRNA

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

G

GA binding protein transcription factor subunit beta 2

decreases expression

Vitamin E results in decreased expression of GABPB2 mRNA

NCBI chr 2:182,755,304...182,795,368
Ensembl chr 2:182,761,359...182,795,109

G

growth arrest and DNA-damage-inducible, alpha

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of GADD45A mRNA
Vitamin E results in decreased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

cyclin G associated kinase

decreases expression

Vitamin E results in decreased expression of GAK mRNA

NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398

G

polypeptide N-acetylgalactosaminyltransferase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GALNT1 mRNA
Vitamin E results in decreased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

polypeptide N-acetylgalactosaminyltransferase 10

decreases expression

Vitamin E results in decreased expression of GALNT10 mRNA

NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013

G

polypeptide N-acetylgalactosaminyltransferase 3

decreases expression

Vitamin E results in decreased expression of GALNT3 mRNA

NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268

G

galanin receptor 3

increases expression

Vitamin E results in increased expression of GALR3 mRNA

NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

Vitamin E results in increased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

growth arrest specific 8

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GAS8 mRNA
Vitamin E results in increased expression of GAS8 mRNA

NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305

G

GATA binding protein 4

affects expression

Vitamin E affects the expression of GATA4 mRNA

NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636

G

GATA zinc finger domain containing 1

decreases expression

Vitamin E results in decreased expression of GATAD1 mRNA

NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107

G

glutamine amidotransferase class 1 domain containing 3A

increases expression

Vitamin E results in increased expression of GATD3 mRNA

NCBI chr20:10,514,793...10,522,894
Ensembl chr20:10,514,744...10,522,885

G

guanylate binding protein 1

decreases expression

Vitamin E results in decreased expression of GBP1 mRNA

NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131

G

GC-rich sequence DNA-binding factor 2

decreases expression

Vitamin E results in decreased expression of GCFC2 mRNA

NCBI chr 4:114,481,613...114,519,268
Ensembl chr 4:114,481,607...114,519,962

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
affects expression

Vitamin E inhibits the reaction [Alcohols results in increased expression of GCLC mRNA]
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of GCLC mRNA; Vitamin E affects the reaction [[REL binds to GCLC promoter] which affects the expression of GCLC mRNA]
Vitamin E affects the expression of GCLC mRNA; Vitamin E affects the expression of GCLC protein

PMID:11444866 PMID:16298738 PMID:18814483

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

multiple interactions
affects expression

Vitamin E affects the reaction [[REL binds to GCLM promoter] which affects the expression of GCLM mRNA]
Vitamin E affects the expression of GCLM mRNA

PMID:16298738 PMID:20447326

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

ganglioside-induced differentiation-associated protein 1-like 1

decreases expression

Vitamin E results in decreased expression of GDAP1L1 mRNA

NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711

G

GDP dissociation inhibitor 1

increases expression

Vitamin E results in increased expression of GDI1 mRNA

NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272

G

glial fibrillary acidic protein

multiple interactions

Vitamin E inhibits the reaction [Aluminum results in increased expression of GFAP protein]

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

Gfo/Idh/MocA-like oxidoreductase domain containing 1

increases expression

Vitamin E results in increased expression of GFOD1 mRNA

NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938

G

GDP-L-fucose synthase

increases expression

Vitamin E results in increased expression of GFUS mRNA

NCBI chr 7:107,612,087...107,617,005
Ensembl chr 7:107,612,094...107,616,948

G

geranylgeranyl diphosphate synthase 1

decreases expression

Vitamin E results in decreased expression of GGPS1 mRNA

NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220

G

gamma-glutamyltransferase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of GGT1 mRNA
Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GGT1 protein]

PMID:16298753 PMID:19244175

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

G

GRB10 interacting GYF protein 2

decreases expression

Vitamin E results in decreased expression of GIGYF2 mRNA

NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715

G

GTPase, IMAP family member 5

increases expression

Vitamin E results in increased expression of GIMAP5 mRNA

NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086

G

GIPC PDZ domain containing family, member 1

increases expression
multiple interactions

Vitamin E results in increased expression of GIPC1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of GIPC1 mRNA

NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997

G

gap junction protein, alpha 1

multiple interactions

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of GJA1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 protein]

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

golgi glycoprotein 1

decreases expression
increases expression

Vitamin E results in decreased expression of GLG1 mRNA
Vitamin E results in increased expression of GLG1 mRNA

NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178

G

GLI family zinc finger 2

increases expression

Vitamin E results in increased expression of GLI2 mRNA

NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574

G

glomulin, FKBP associated protein

decreases expression

Vitamin E results in decreased expression of GLMN mRNA

NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420

G

GDP-mannose pyrophosphorylase A

increases expression

Vitamin E results in increased expression of GMPPA mRNA

NCBI chr 9:76,926,724...76,934,274
Ensembl chr 9:76,926,739...76,934,269

G

GNAS complex locus

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of GNAS mRNA

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

G protein subunit alpha z

increases expression

Vitamin E results in increased expression of GNAZ mRNA

NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907

G

G protein subunit gamma 4

decreases expression

Vitamin E results in decreased expression of GNG4 mRNA

NCBI chr17:86,448,708...86,497,560
Ensembl chr17:86,449,022...86,495,254

G

golgin A3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GOLGA3 mRNA
Vitamin E results in increased expression of GOLGA3 mRNA

NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509

G

golgi SNAP receptor complex member 1

decreases expression

Vitamin E results in decreased expression of GOSR1 mRNA

NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177
Ensembl chr10:61,450,494...61,607,177

G

glutamic-oxaloacetic transaminase 1

multiple interactions

Vitamin E inhibits the reaction [Hexachlorobenzene results in increased activity of GOT1 protein]; Vitamin E inhibits the reaction [Tramadol results in increased expression of GOT1 protein]

PMID:30064338 PMID:31618080

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycoprotein VI

decreases expression

Vitamin E results in decreased expression of GP6 mRNA

NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326

G

G patch domain containing 8

decreases expression

Vitamin E results in decreased expression of GPATCH8 mRNA

NCBI chr10:87,432,020...87,512,594
Ensembl chr10:87,433,266...87,512,419

G

glucose-6-phosphate isomerase

increases expression

Vitamin E results in increased expression of GPI mRNA

NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086

G

G patch domain and KOW motifs

increases expression

Vitamin E results in increased expression of GPKOW mRNA

NCBI chr X:14,791,601...14,806,384
Ensembl chr X:14,791,610...14,806,384

G

GPN-loop GTPase 3

decreases expression

Vitamin E results in decreased expression of GPN3 mRNA

NCBI chr12:34,189,285...34,198,251
Ensembl chr12:34,189,577...34,198,206

G

G protein-coupled receptor 107

increases expression

Vitamin E results in increased expression of GPR107 mRNA

NCBI chr 3:14,431,704...14,497,623
Ensembl chr 3:14,434,723...14,495,958

G

G protein regulated inducer of neurite outgrowth 2

decreases expression
multiple interactions

Vitamin E results in decreased expression of GPRIN2 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of GPRIN2 mRNA

NCBI chr16:9,496,452...9,512,672
Ensembl chr16:9,505,643...9,507,010

G

glutamic--pyruvic transaminase

multiple interactions

[Quercetin co-treated with Vitamin E] inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Cyclophosphamide results in increased expression of GPT protein]; Vitamin E inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Food Additives results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Hexachlorobenzene results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Tramadol results in increased expression of GPT protein]

PMID:16758767 PMID:17927767 PMID:25779342 PMID:30064338 PMID:31618080

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions
decreases expression

[Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 mRNA; [Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein; Vitamin E inhibits the reaction [Aluminum results in decreased activity of GPX1 protein]
Vitamin E decreases expression of Gpx1 mRNA in distal colon
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GPX1 protein]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in increased expression of GPX1 protein]; [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of GPX1 mRNA; [Vitamin E co-treated with Folic Acid] inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GPX1 protein]; Vitamin E inhibits the reaction [Endosulfan results in increased activity of GPX1 protein]; Vitamin E inhibits the reaction [Hexachlorobenzene results in increased activity of GPX1 protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of GPX1 mRNA]

CTD
RGD

PMID:11444866 PMID:15337585 PMID:16298753 PMID:17179735 PMID:17709913 More...

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

multiple interactions

Vitamin E inhibits the reaction [phoxim results in increased expression of GPX2 mRNA]

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 3

increases expression

Vitamin E results in increased expression of GPX3 mRNA

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glyoxylate and hydroxypyruvate reductase

increases expression

Vitamin E results in increased expression of GRHPR mRNA

NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603

G

glutamate ionotropic receptor AMPA type subunit 2

decreases expression

Vitamin E results in decreased expression of GRIA2 mRNA

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

G protein-coupled receptor kinase 3

decreases expression

Vitamin E results in decreased expression of GRK3 mRNA

NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262

G

granulin precursor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of GRN mRNA
Vitamin E results in increased expression of GRN mRNA

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

glycogen synthase kinase 3 alpha

increases expression

Vitamin E results in increased expression of GSK3A mRNA

NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802

G

glycogen synthase kinase 3 beta

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA
Vitamin E results in decreased expression of GSK3B mRNA
Vitamin E inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]

PMID:15842767 PMID:19244175

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

gelsolin

increases expression

Vitamin E results in increased expression of GSN mRNA

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

G

glutathione-disulfide reductase

multiple interactions

Vitamin E inhibits the reaction [Cadmium results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Ethanol results in decreased activity of GSR protein]
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]; [Vitamin E co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in decreased activity of GSR protein]; [Vitamin E co-treated with coenzyme Q10] results in increased activity of GSR protein; [Vitamin E co-treated with Folic Acid] inhibits the reaction [Hydrogen Peroxide results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Cadmium results in increased activity of GSR protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Diethylnitrosamine results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Hydrogen Peroxide results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Methoxychlor results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of GSR protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]

PMID:11955947 PMID:12355564 PMID:14535831 PMID:16144695 PMID:16298753 More...

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase kappa 1

increases expression

Vitamin E results in increased expression of GSTK1 mRNA

NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase, mu 5-like

increases expression

Vitamin E results in increased expression of GSTM5 mRNA

NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

increases expression
multiple interactions

Vitamin E results in increased expression of GSTP1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

general transcription factor IIF subunit 1

decreases expression

Vitamin E results in decreased expression of GTF2F1 mRNA

NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423

G

GTF2I repeat domain containing 1

decreases expression

Vitamin E results in decreased expression of GTF2IRD1 mRNA

NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040

G

GTP binding protein 8

decreases expression
multiple interactions

Vitamin E results in decreased expression of GTPBP8 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of GTPBP8 mRNA

NCBI chr11:55,945,778...55,955,743
Ensembl chr11:55,945,795...55,955,635

G

H3.3 histone A

decreases expression

Vitamin E results in decreased expression of H3-3A mRNA

NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

increases expression
multiple interactions

Vitamin E results in increased expression of H6PD mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of H6PD mRNA

NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

Vitamin E results in decreased expression of HADHA mRNA

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl glutathione hydrolase

increases expression

Vitamin E results in increased expression of HAGH mRNA

NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504

G

hepcidin antimicrobial peptide

multiple interactions

Vitamin E inhibits the reaction [Ethanol results in decreased expression of HAMP mRNA]

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

histidyl-tRNA synthetase 1

increases expression

Vitamin E results in increased expression of HARS1 mRNA

NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740

G

HAUS augmin-like complex, subunit 3

decreases expression

Vitamin E results in decreased expression of HAUS3 mRNA

NCBI chr14:76,580,549...76,599,542
Ensembl chr14:76,580,546...76,752,463

G

HAUS augmin-like complex, subunit 4

increases expression

Vitamin E results in increased expression of HAUS4 mRNA

NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938

G

hemoglobin alpha, adult chain 2

decreases expression

Vitamin E results in decreased expression of HBA1 protein

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin alpha, adult chain 3

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of HBA2 mRNA

NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481

G

host cell factor C1

increases expression

Vitamin E results in increased expression of HCFC1 mRNA

NCBI chr X:151,687,779...151,712,688
Ensembl chr X:151,687,779...151,712,638

G

histone deacetylase 1

increases expression

Vitamin E results in increased expression of HDAC1 mRNA

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

G

histone deacetylase 5

increases expression

Vitamin E results in increased expression of HDAC5 mRNA

NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235

G

HemK methyltransferase family member 1

increases expression

Vitamin E results in increased expression of HEMK1 mRNA

NCBI chr 8:107,999,658...108,010,732
Ensembl chr 8:107,999,644...108,010,256

G

hes family bHLH transcription factor 1

decreases expression
multiple interactions

Vitamin E results in decreased expression of HES1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HES1 protein]
[Selenium co-treated with Vitamin E] results in increased expression of HES1 mRNA

PMID:19244175 PMID:29663635

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hypoxia inducible factor 1 subunit alpha

decreases expression

Vitamin E results in decreased expression of HIF1A protein

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hypoxia inducible factor 1 subunit alpha inhibitor

increases expression

Vitamin E results in increased expression of HIF1AN mRNA

NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327

G

HIG1 hypoxia inducible domain family, member 2A

increases expression

Vitamin E results in increased expression of HIGD2A mRNA

NCBI chr17:10,021,853...10,022,777
Ensembl chr17:10,021,859...10,022,796

G

homeodomain interacting protein kinase 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HIPK2 mRNA
Vitamin E results in decreased expression of HIPK2 mRNA

NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223

G

5-hydroxymethylcytosine binding, ES cell specific

increases expression

Vitamin E results in increased expression of HMCES mRNA

NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616

G

high mobility group box 1

decreases expression
multiple interactions

Vitamin E results in decreased expression of HMGB1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HMGB1 mRNA

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

HMG-box containing 4

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HMGXB4 mRNA
Vitamin E results in decreased expression of HMGXB4 mRNA

NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563

G

heme oxygenase 1

multiple interactions
increases expression

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]
[Vitamin E co-treated with bioallethrin] results in increased expression of HMOX1 protein; Vitamin E inhibits the reaction [Polychlorinated Biphenyls analog results in increased expression of HMOX1 protein]
Vitamin E results in increased expression of HMOX1 mRNA

PMID:15571180 PMID:24361488 PMID:29663635 PMID:29940330 PMID:30513525 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

histamine N-methyltransferase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HNMT mRNA
Vitamin E results in decreased expression of HNMT mRNA

NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012

G

heterogeneous nuclear ribonucleoprotein M

increases expression

Vitamin E results in increased expression of HNRNPM mRNA

NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762

G

heterogeneous nuclear ribonucleoprotein R

decreases expression

Vitamin E results in decreased expression of HNRNPR mRNA

NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867

G

homer scaffold protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HOMER1 mRNA
Vitamin E results in decreased expression of HOMER1 mRNA

NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785

G

hook microtubule-tethering protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HOOK1 mRNA
Vitamin E results in decreased expression of HOOK1 mRNA

NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787

G

homeobox A11

increases expression

Vitamin E results in increased expression of HOXA11 mRNA

NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232

G

homeobox A7

decreases expression

Vitamin E results in decreased expression of HOXA7 mRNA

NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659

G

hippocalcin-like 1

increases expression
multiple interactions

Vitamin E results in increased expression of HPCAL1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HPCAL1 mRNA

NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687

G

hypoxanthine phosphoribosyltransferase 1

multiple interactions

Vitamin E inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene]

NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154

G

HRas proto-oncogene, GTPase

multiple interactions
increases expression

Vitamin E inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS protein]]
Vitamin E results in increased expression of HRAS mRNA
[Selenium co-treated with Vitamin E] results in increased expression of HRAS mRNA

PMID:11062179 PMID:19244175

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

Vitamin E results in increased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions

Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD17B3 mRNA]

NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554

G

hydroxysteroid (17-beta) dehydrogenase 8

increases expression

Vitamin E results in increased expression of HSD17B8 mRNA

NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

multiple interactions

Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD3B1 mRNA]

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

heat shock protein 90 alpha family class A member 1

decreases expression
multiple interactions

Vitamin E results in decreased expression of HSP90AA1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HSP90AA1 mRNA

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 alpha family class B member 1

increases expression

Vitamin E results in increased expression of HSP90AB1 mRNA

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein 90 beta family member 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HSP90B1 mRNA
Vitamin E results in decreased expression of HSP90B1 mRNA

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 1A

increases expression

Vitamin E results in increased expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 4

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of HSPA4 mRNA
Vitamin E results in increased expression of HSPA4 mRNA

NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family A (Hsp70) member 5

multiple interactions

Vitamin E inhibits the reaction [pyrazole results in increased expression of HSPA5 protein]

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 9

decreases expression
multiple interactions

Vitamin E results in decreased expression of HSPA9 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HSPA9 mRNA

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

G

heat shock protein family B (small) member 1

increases expression

Vitamin E results in increased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

HtrA serine peptidase 1

increases expression

Vitamin E results in increased expression of HTRA1 mRNA

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

HtrA serine peptidase 2

multiple interactions

Vitamin E inhibits the reaction [cinnamaldehyde affects the localization of HTRA2 protein]

NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095

G

isoleucyl-tRNA synthetase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of IARS1 mRNA
Vitamin E results in decreased expression of IARS1 mRNA

NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237

G

islet cell autoantigen 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ICA1 mRNA
Vitamin E results in increased expression of ICA1 mRNA

NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298

G

intercellular adhesion molecule 1

multiple interactions

[Vitamin E co-treated with Bezafibrate] results in decreased expression of ICAM1 protein modified form; Vitamin E inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ICAM1 protein]; Vitamin E inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Vitamin E inhibits the reaction [Simvastatin results in decreased expression of ICAM1 protein modified form]

PMID:14602771 PMID:23114885 PMID:35349355

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 2

decreases expression

Vitamin E results in decreased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

increases expression

Vitamin E results in increased expression of IDH3B mRNA

NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of IDH3G mRNA
Vitamin E results in increased expression of IDH3G mRNA

NCBI chr X:151,515,244...151,524,175
Ensembl chr X:151,515,247...151,524,171

G

iduronate 2-sulfatase

increases expression

Vitamin E results in increased expression of IDS mRNA

NCBI chr X:149,025,976...149,046,641
Ensembl chr X:149,025,976...149,046,663

G

alpha-L-iduronidase

increases expression
multiple interactions

Vitamin E results in increased expression of IDUA mRNA
[Selenium co-treated with Vitamin E] results in increased expression of IDUA mRNA

NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522

G

intermediate filament family orphan 1

increases expression

Vitamin E results in increased expression of IFFO1 mRNA

NCBI chr 4:157,945,075...157,962,302
Ensembl chr 4:157,945,107...157,962,302

G

interferon-induced protein 35

increases expression

Vitamin E results in increased expression of IFI35 mRNA

NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952

G

interferon induced transmembrane protein 1

increases expression

Vitamin E results in increased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

interferon induced transmembrane protein 2

increases expression

Vitamin E results in increased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

increases expression

Vitamin E results in increased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

interferon gamma

multiple interactions
decreases expression

Vitamin E inhibits the reaction [Ethanol results in increased activity of IFNG protein]
Vitamin E inhibits the reaction [APP protein modified form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]]
Vitamin E results in decreased expression of IFNG protein

PMID:14624943 PMID:15223066 PMID:21086752

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

intraflagellar transport 74

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of IFT74 mRNA
Vitamin E results in decreased expression of IFT74 mRNA

NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:109,474,255...109,563,833

G

intraflagellar transport 81

decreases expression

Vitamin E results in decreased expression of IFT81 mRNA

NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057

G

insulin-like growth factor 1 receptor

multiple interactions
decreases expression

Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein]
Vitamin E inhibits the reaction [Thyroxine results in increased expression of IGF1R protein]
Vitamin E results in decreased expression of IGF1R mRNA; Vitamin E results in decreased expression of IGF1R protein

PMID:17447016 PMID:19244175 PMID:20015448

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2 mRNA binding protein 2

decreases expression

Vitamin E results in decreased expression of IGF2BP2 mRNA

NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377

G

insulin-like growth factor 2 receptor

decreases expression

Vitamin E results in decreased expression of IGF2R mRNA

NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein 2

increases expression

Vitamin E results in increased expression of IGFBP2 mRNA

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 4

increases expression

Vitamin E results in increased expression of IGFBP4 mRNA

NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225

G

insulin-like growth factor binding protein 6

increases expression

Vitamin E results in increased expression of IGFBP6 mRNA

NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966

G

IK cytokine

increases expression

Vitamin E results in increased expression of IK mRNA

NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832

G

interleukin 10

multiple interactions

Vitamin E inhibits the reaction [Ethanol results in increased activity of IL10 protein]
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]

PMID:15862027 PMID:21086752

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 13

multiple interactions

Vitamin E inhibits the reaction [Ozone results in increased expression of IL13 protein]

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 13 receptor subunit alpha 1

increases expression

Vitamin E results in increased expression of IL13RA1 mRNA

NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681

G

interleukin 1 beta

multiple interactions
increases expression

alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Vitamin E deficiency results in increased expression of IL1B mRNA]
Vitamin E inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]
Vitamin E inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased chemical synthesis of Nitric Oxide]; Vitamin E inhibits the reaction [[IL1B protein co-treated with TNF protein] results in increased expression of NOS2 protein]; Vitamin E inhibits the reaction [Aluminum results in increased expression of IL1B protein]; Vitamin E inhibits the reaction [Vehicle Emissions results in increased expression of IL1B mRNA]

PMID:15223066 PMID:16545059 PMID:18234736 PMID:19735175 PMID:35349355

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

multiple interactions

Vitamin E inhibits the reaction [Formaldehyde results in increased expression of IL2 protein]

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

decreases expression
multiple interactions

Vitamin E results in decreased expression of IL4 protein
Vitamin E inhibits the reaction [Ozone results in increased expression of IL4 protein]
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] results in increased expression of IL4 protein

PMID:14624943 PMID:15862027 PMID:30090343

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 4 receptor

increases expression
multiple interactions

Vitamin E results in increased expression of IL4R mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of IL4R mRNA

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 5

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL5 mRNA
Vitamin E inhibits the reaction [Ozone results in increased expression of IL5 protein]

PMID:16797527 PMID:30090343

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

multiple interactions
decreases expression

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL6 mRNA; Vitamin E inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]
Vitamin E inhibits the reaction [phoxim results in decreased expression of IL6 mRNA]; Vitamin E inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; Vitamin E inhibits the reaction [Vehicle Emissions results in increased expression of IL6 protein]
Vitamin E results in decreased expression of IL6 protein

PMID:16797527 PMID:18234736 PMID:20370442 PMID:30003487 PMID:35349355

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin enhancer binding factor 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of ILF3 mRNA
Vitamin E results in decreased expression of ILF3 mRNA

NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350

G

integrin-linked kinase

increases expression

Vitamin E results in increased expression of ILK mRNA

NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140

G

inositol polyphosphate-5-phosphatase K

increases expression

Vitamin E results in increased expression of INPP5K mRNA

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

G

insulin 1

multiple interactions

[Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 mRNA; [Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of INS1 protein]; Vitamin E inhibits the reaction [Triiodothyronine, Reverse inhibits the reaction [INS1 protein results in increased uptake of Glucose]]

PMID:17198541 PMID:20108212 PMID:21911000

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin receptor

multiple interactions

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of INSR mRNA]

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

G

integrator complex subunit 15

increases expression

Vitamin E results in increased expression of INTS15 mRNA

NCBI chr12:11,245,045...11,260,170
Ensembl chr12:11,245,842...11,260,166

G

integrator complex subunit 6

decreases expression
multiple interactions

Vitamin E results in decreased expression of INTS6 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of INTS6 mRNA

NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527

G

intracisternal A particle-promoted polypeptide

decreases expression

Vitamin E results in decreased expression of IPP mRNA

NCBI chr 5:129,962,528...130,001,237
Ensembl chr 5:129,962,643...130,001,242

G

IQ motif containing B1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of IQCB1 mRNA

NCBI chr11:63,905,595...63,960,141
Ensembl chr11:63,905,590...63,960,093

G

IQ motif containing K

decreases expression
multiple interactions

Vitamin E results in decreased expression of IQCK mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of IQCK mRNA

NCBI chr 1:173,199,308...173,316,982
Ensembl chr 1:173,199,316...173,316,984

G

IQ motif containing GTPase activating protein 1

decreases expression

Vitamin E results in decreased expression of IQGAP1 mRNA

NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755

G

IQ motif and Sec7 domain ArfGEF 1

increases expression

Vitamin E results in increased expression of IQSEC1 mRNA

NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172

G

interferon regulatory factor 9

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of IRF9 mRNA
Vitamin E results in increased expression of IRF9 mRNA

NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236

G

insulin receptor substrate 1

multiple interactions
decreases expression

Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IRS1 protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of IRS1 protein]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of IRS1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of IRS1 protein]

PMID:20015448 PMID:21911000

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

iron-sulfur cluster assembly 1

decreases expression

Vitamin E results in decreased expression of ISCA1 mRNA

NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955

G

immunoglobulin superfamily containing leucine-rich repeat

increases expression

Vitamin E results in increased expression of ISLR mRNA

NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130

G

inositol-3-phosphate synthase 1

increases expression

Vitamin E results in increased expression of ISYNA1 mRNA

NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979

G

integrin subunit alpha 3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ITGA3 mRNA
Vitamin E results in increased expression of ITGA3 mRNA

NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118

G

integrin subunit beta 3 binding protein

decreases expression

Vitamin E results in decreased expression of ITGB3BP mRNA

NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704

G

integral membrane protein 2C

increases expression

Vitamin E results in increased expression of ITM2C mRNA

NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742

G

inositol-trisphosphate 3-kinase B

increases expression

Vitamin E results in increased expression of ITPKB mRNA

NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases phosphorylation
decreases expression

Rutin results in increased susceptibility to [Vitamin E results in decreased expression of JUN protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of JUN protein]
Vitamin E promotes the reaction [Alcohols results in increased expression of JUN mRNA]
Vitamin E results in increased phosphorylation of JUN protein
Vitamin E results in decreased expression of JUN mRNA; Vitamin E results in decreased expression of JUN protein

PMID:11522656 PMID:18814483 PMID:19244175 PMID:20015448

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

lysine acetyltransferase 5

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of KAT5 mRNA

NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458

G

kelch repeat and BTB domain containing 2

increases expression

Vitamin E results in increased expression of KBTBD2 mRNA

NCBI chr 4:86,027,947...86,050,266
Ensembl chr 4:86,027,947...86,050,211

G

potassium voltage-gated channel subfamily H member 2

multiple interactions
increases expression

Vitamin E inhibits the reaction [TNF protein results in decreased activity of KCNH2 protein]
Vitamin E results in increased expression of KCNH2 mRNA

PMID:14973143 PMID:19244175

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

potassium inwardly-rectifying channel, subfamily J, member 5

decreases expression

Vitamin E results in decreased expression of KCNJ5 mRNA

NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518

G

potassium inwardly-rectifying channel, subfamily J, member 8

increases expression

Vitamin E results in increased expression of KCNJ8 mRNA

NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603

G

potassium channel tetramerization domain containing 17

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KCTD17 mRNA

NCBI chr 7:109,979,060...110,009,091
Ensembl chr 7:109,979,060...110,008,927

G

potassium channel tetramerization domain containing 2

increases expression

Vitamin E results in increased expression of KCTD2 mRNA

NCBI chr10:100,663,013...100,674,756
Ensembl chr10:100,662,884...100,674,336

G

lysine demethylase 6B

increases expression

Vitamin E results in increased expression of KDM6B mRNA

NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794

G

KH RNA binding domain containing, signal transduction associated 1

decreases expression

Vitamin E results in decreased expression of KHDRBS1 mRNA

NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180

G

KIAA0930 homolog

increases expression

Vitamin E results in increased expression of KIAA0930 mRNA

NCBI chr 7:116,067,974...116,107,678
Ensembl chr 7:116,071,447...116,107,727

G

kinesin family member 16B

decreases expression

Vitamin E results in decreased expression of KIF16B mRNA

NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019

G

kinesin family member 1B

decreases expression

Vitamin E results in decreased expression of KIF1B mRNA

NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778

G

kinesin family member 5B

decreases expression

Vitamin E results in decreased expression of KIF5B mRNA

NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508

G

kinesin family member 5C

decreases expression

Vitamin E results in decreased expression of KIF5C mRNA

NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413

G

Klotho

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KL mRNA

NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080

G

kinesin light chain 1

increases expression

Vitamin E results in increased expression of KLC1 mRNA

NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031

G

KLF transcription factor 6

multiple interactions

Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Paraquat] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [[CYP2E1 protein co-treated with Vitamin K 3] results in increased expression of KLF6 protein]; Vitamin E inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

KLF transcription factor 9

decreases expression

Vitamin E results in decreased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

kelch domain containing 10

decreases expression

Vitamin E results in decreased expression of KLHDC10 mRNA

NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941

G

kelch-like family member 20

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KLHL20 mRNA
Vitamin E results in decreased expression of KLHL20 mRNA

NCBI chr13:73,363,451...73,408,293
Ensembl chr13:73,363,455...73,408,337

G

kelch-like family member 24

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

kelch-like family member 4

decreases expression

Vitamin E results in decreased expression of KLHL4 mRNA

NCBI chr X:79,429,193...79,719,482
Ensembl chr X:79,622,113...79,719,480

G

kelch-like family member 9

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KLHL9 mRNA

NCBI chr 5:103,333,747...103,337,931

G

lysine methyltransferase 2B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of KMT2B mRNA
Vitamin E results in increased expression of KMT2B mRNA

NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326

G

karyopherin subunit alpha 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KPNA1 mRNA
Vitamin E results in decreased expression of KPNA1 mRNA

NCBI chr11:64,715,844...64,774,647
Ensembl chr11:64,717,563...64,774,623

G

karyopherin subunit alpha 3

decreases expression

Vitamin E results in decreased expression of KPNA3 mRNA

NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419

G

karyopherin subunit beta 1

decreases expression
increases expression
multiple interactions

Vitamin E results in decreased expression of KPNB1 mRNA
Vitamin E results in increased expression of KPNB1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of KPNB1 mRNA

NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605

G

kinectin 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KTN1 mRNA
Vitamin E results in decreased expression of KTN1 mRNA

NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578

G

ladinin 1

decreases expression

Vitamin E results in decreased expression of LAD1 mRNA

NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967

G

laminin subunit beta 2

increases expression

Vitamin E results in increased expression of LAMB2 mRNA

NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549

G

lysosomal-associated membrane protein 1

increases expression

Vitamin E results in increased expression of LAMP1 mRNA

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

G

lysosomal-associated membrane protein 2

multiple interactions

Vitamin E inhibits the reaction [Pilocarpine results in increased expression of LAMP2 protein]

NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522

G

La ribonucleoprotein 4B

decreases expression

Vitamin E results in decreased expression of LARP4B mRNA

NCBI chr17:61,138,663...61,217,423
Ensembl chr17:61,138,709...61,187,960

G

leucine carboxyl methyltransferase 2

increases expression

Vitamin E results in increased expression of LCMT2 mRNA; Vitamin E results in increased expression of LCMT2 protein

NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084

G

LIM domain binding 2

increases expression

Vitamin E results in increased expression of LDB2 mRNA

NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778

G

lactate dehydrogenase A

multiple interactions

Vitamin E inhibits the reaction [Hexachlorobenzene affects the expression of LDHA protein]

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

leptin

multiple interactions

Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of LEP mRNA]; Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of LEP protein]

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

luteinizing hormone subunit beta

multiple interactions

[Vitamin E co-treated with LHB protein] results in increased chemical synthesis of Testosterone; Vitamin E inhibits the reaction [acetamiprid results in increased expression of LHB protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in decreased expression of LHB protein]; Vitamin E inhibits the reaction [cypermethrin results in decreased expression of LHB protein]; Vitamin E inhibits the reaction [Petroleum results in decreased expression of LHB protein]; Vitamin E inhibits the reaction [Potassium Dichromate results in decreased expression of LHB protein]

PMID:16054318 PMID:16298753 PMID:17280759 PMID:20079796 PMID:24759048 More...

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LIM and calponin homology domains 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of LIMCH1 mRNA

NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191

G

lipoyltransferase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of LIPT1 mRNA
Vitamin E results in decreased expression of LIPT1 mRNA

NCBI chr 9:40,107,938...40,118,268
Ensembl chr 9:40,098,615...40,113,565

G

lectin, mannose-binding 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of LMAN2 mRNA
Vitamin E results in increased expression of LMAN2 mRNA

NCBI chr17:9,269,236...9,286,923
Ensembl chr17:9,269,022...9,287,265

G

lamin A/C

increases expression

Vitamin E results in increased expression of LMNA mRNA

NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,