CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: picene
Accession: CHEBI:33090
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Definition: An ortho-fused polycyclic arene consisting of five fused benzene rings. It is obtained during the distillation of petroleum.
Synonyms: related_synonym: 1,2:7,8-dibenzophenanthrene; 3,4-benzchrysene; Benzo[a]chrysene; Formula=C22H14; InChI=1S/C22H14/c1-3-7-17-15(5-1)9-11-21-19(17)13-14-20-18-8-4-2-6-16(18)10-12-22(20)21/h1-14H; InChIKey=GBROPGWFBFCKAG-UHFFFAOYSA-N; SMILES=c1ccc2c(c1)ccc1c2ccc2c3ccccc3ccc12; beta,beta-binaphthyleneethene
xref: CAS:213-46-7; KEGG:C19500
xref_mesh: MESH:C056699
xref: Reaxys:1912414; Wikipedia:Picene
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Abcc5
ATP binding cassette subfamily C member 5
increases expression
ISO
picene results in increased expression of ABCC5 mRNA
CTD
PMID:32251684
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:80,473,872...80,567,253
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Abhd2
abhydrolase domain containing 2, acylglycerol lipase
decreases expression
ISO
picene results in decreased expression of ABHD2 mRNA
CTD
PMID:32251684
NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:133,217,375...133,299,061
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Adora1
adenosine A1 receptor
decreases expression
ISO
picene results in decreased expression of ADORA1 mRNA
CTD
PMID:32251684
NCBI chr13:48,210,922...48,247,826
Ensembl chr13:45,658,872...45,695,801
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Ahr
aryl hydrocarbon receptor
affects binding multiple interactions increases activity
EXP
picene binds to AHR protein picene inhibits the reaction [Benzo(a)pyrene binds to AHR protein]; picene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein] picene results in increased activity of AHR protein
CTD
PMID:3024361 PMID:28104439 PMID:29471110
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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Ahrr
aryl-hydrocarbon receptor repressor
increases expression
ISO
picene results in increased expression of AHRR mRNA
CTD
PMID:32251684
NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:28,993,634...29,088,673
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
picene results in increased expression of ALDH1A3 mRNA
CTD
PMID:32251684
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:119,982,277...120,017,436
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Aldh3a1
aldehyde dehydrogenase 3 family, member A1
increases expression
ISO
picene results in increased expression of ALDH3A1 mRNA
CTD
PMID:32251684
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:45,892,924...45,902,681
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Amer2
APC membrane recruitment protein 2
increases expression
ISO
picene results in increased expression of AMER2 mRNA
CTD
PMID:32251684
NCBI chr15:38,701,509...38,711,817
Ensembl chr15:34,524,542...34,528,455
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Atoh8
atonal bHLH transcription factor 8
increases expression
ISO
picene results in increased expression of ATOH8 mRNA
CTD
PMID:32251684
NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:104,259,992...104,292,168
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Bpifa5
BPI fold containing family A, member 5
increases expression
ISO
picene results in increased expression of BPIFA4P mRNA
CTD
PMID:32251684
NCBI chr 3:163,106,258...163,113,039
Ensembl chr 3:142,646,103...142,652,883
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Ccng2
cyclin G2
increases expression
ISO
picene results in increased expression of CCNG2 mRNA
CTD
PMID:32251684
NCBI chr14:15,088,694...15,097,190
Ensembl chr14:14,804,322...14,812,830
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Cebpb
CCAAT/enhancer binding protein beta
decreases expression
ISO
picene results in decreased expression of CEBPB mRNA
CTD
PMID:32251684
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473
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Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
decreases expression
ISO
picene results in decreased expression of CELSR2 mRNA
CTD
PMID:32251684
NCBI chr 2:198,717,333...198,741,689
Ensembl chr 2:196,029,434...196,053,845
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Cntnap3
contactin associated protein family member 3
increases expression
ISO
picene results in increased expression of CNTNAP3 mRNA
CTD
PMID:32251684
NCBI chr17:267,379...455,478
Ensembl chr17:267,508...454,102
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Ctsd
cathepsin D
decreases expression
ISO
picene results in decreased expression of CTSD mRNA
CTD
PMID:32251684
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
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Cxcl12
C-X-C motif chemokine ligand 12
decreases expression
ISO
picene results in decreased expression of CXCL12 mRNA
CTD
PMID:32251684
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP ISO
picene results in increased expression of CYP1A1 protein picene results in increased expression of CYP1A1 mRNA
CTD
PMID:28104439 PMID:32251684
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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Ddit4
DNA-damage-inducible transcript 4
increases expression
ISO
picene results in increased expression of DDIT4 mRNA
CTD
PMID:32251684
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105
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Esr1
estrogen receptor 1
affects binding
ISO
picene binds to ESR1 protein
CTD
PMID:32251684
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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Fam47e
family with sequence similarity 47, member E
decreases expression
ISO
picene results in decreased expression of FAM47E mRNA
CTD
PMID:32251684
NCBI chr14:15,485,537...15,521,599
Ensembl chr14:15,485,127...15,521,775
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Fmn1
formin 1
decreases expression
ISO
picene results in decreased expression of FMN1 mRNA
CTD
PMID:32251684
NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:100,134,549...100,479,220
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Gdf1
growth differentiation factor 1
increases expression
ISO
picene results in increased expression of GDF1 mRNA
CTD
PMID:32251684
NCBI chr16:19,131,271...19,146,480
Ensembl chr16:19,097,314...19,112,519
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H1f4
H1.4 linker histone, cluster member
increases expression
ISO
picene results in increased expression of H1-4 mRNA
CTD
PMID:32251684
NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,486,560...41,487,403
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H1f5
H1.5 linker histone, cluster member
increases expression
ISO
picene results in increased expression of H1-5 mRNA
CTD
PMID:32251684
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:42,726,127...42,769,160
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H4f3
H1.3 linker histone, cluster member
increases expression
ISO
picene results in increased expression of H1-3 mRNA
CTD
PMID:32251684
NCBI chr17:41,979,562...41,980,341
Ensembl chr17:41,529,667...41,552,334
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Hist1h2ah
histone cluster 1 H2A family member H
increases expression
ISO
picene results in increased expression of HIST1H2AH mRNA
CTD
PMID:32251684
NCBI chr17:41,812,378...41,812,875
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Hist1h4b
histone cluster 1 H4 family member B
increases expression
ISO
picene results in increased expression of HIST1H4B mRNA
CTD
PMID:32251684
NCBI chr17:47,176,246...47,180,690
Ensembl chr17:42,480,313...42,485,370
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Ier3
immediate early response 3
increases expression
ISO
picene results in increased expression of IER3 mRNA
CTD
PMID:32251684
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583
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Kcnk6
potassium two pore domain channel subfamily K member 6
decreases expression
ISO
picene results in decreased expression of KCNK6 mRNA
CTD
PMID:32251684
NCBI chr 1:93,652,888...93,661,419
Ensembl chr 1:84,525,590...84,534,677
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Klhl23
kelch-like family member 23
decreases expression
ISO
picene results in decreased expression of PHOSPHO2-KLHL23 mRNA
CTD
PMID:32251684
NCBI chr 3:74,988,778...75,002,347
Ensembl chr 3:54,580,961...54,594,530
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Krt19
keratin 19
decreases expression
ISO
picene results in decreased expression of KRT19 mRNA
CTD
PMID:32251684
NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,066,802...85,171,799
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LOC120096085
U4 spliceosomal RNA
increases expression
ISO
picene results in increased expression of RNU4-1 mRNA
CTD
PMID:32251684
NCBI chr12:41,126,050...41,126,190
Ensembl chr12:41,126,050...41,126,190
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LOC120098377
U1 spliceosomal RNA
increases expression
ISO
picene results in increased expression of RNVU1-7 mRNA
CTD
PMID:32251684
NCBI chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477 Ensembl chr18:79,901,335...79,901,477
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Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
ISO
picene results in increased expression of MYC mRNA
CTD
PMID:32251684
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
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Notch3
notch receptor 3
increases expression
ISO
picene results in increased expression of NOTCH3 mRNA
CTD
PMID:32251684
NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,133,706...11,184,025
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Pgr
progesterone receptor
decreases expression
ISO
picene results in decreased expression of PGR mRNA
CTD
PMID:32251684
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
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Pkib
cAMP-dependent protein kinase inhibitor beta
decreases expression
ISO
picene results in decreased expression of PKIB mRNA
CTD
PMID:32251684
NCBI chr20:37,511,564...37,608,607
Ensembl chr20:36,905,340...37,062,187
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Rara
retinoic acid receptor, alpha
decreases expression
ISO
picene results in decreased expression of RARA mRNA
CTD
PMID:32251684
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:83,893,384...83,928,142
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Ret
ret proto-oncogene
decreases expression
ISO
picene results in decreased expression of RET mRNA
CTD
PMID:32251684
NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176
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Rn7sl1
RNA component of signal recognition particle 7SL1
increases expression
ISO
picene results in increased expression of RN7SL1 mRNA
CTD
PMID:32251684
NCBI chr 6:93,372,872...93,373,170
Ensembl chr 6:87,636,804...87,637,103
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Rnu4-2
RNA, U4 small nuclear 2
increases expression
ISO
picene results in increased expression of RNU4-2 mRNA
CTD
PMID:32251684
NCBI chr 5:124,264,229...124,264,369
Ensembl chr 5:124,264,229...124,264,369
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Rpph1
ribonuclease P RNA component H1
increases expression
ISO
picene results in increased expression of RPPH1 mRNA
CTD
PMID:32251684
NCBI chr15:24,033,679...24,033,935
Ensembl chr15:24,033,662...24,033,959
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Runx2
RUNX family transcription factor 2
increases expression
ISO
picene results in increased expression of RUNX2 mRNA
CTD
PMID:32251684
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
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Scarna10
small Cajal body-specific RNA 10
increases expression
ISO
picene results in increased expression of SCARNA10 mRNA
CTD
PMID:32251684
NCBI chr 4:157,986,558...157,986,885
Ensembl chr 4:157,986,558...157,986,885
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Scarna13
small Cajal body-specific RNA 13
increases expression
ISO
picene results in increased expression of SCARNA13 mRNA
CTD
PMID:32251684
NCBI chr 6:123,986,822...123,987,096
Ensembl chr 6:123,986,822...123,987,096
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Scarna16
small Cajal body-specific RNA 16
increases expression
ISO
picene results in increased expression of SCARNA16 mRNA
CTD
PMID:32251684
NCBI chr10:102,276,365...102,276,548
Ensembl chr10:102,276,365...102,276,548
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Scarna2
small Cajal body-specific RNA 2
increases expression
ISO
picene results in increased expression of SCARNA2 mRNA
CTD
PMID:32251684
NCBI chr 2:196,189,609...196,190,024
Ensembl chr 2:196,189,609...196,190,024
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Sema3b
semaphorin 3B
decreases expression
ISO
picene results in decreased expression of SEMA3B mRNA
CTD
PMID:32251684
NCBI chr 8:117,150,307...117,161,570
Ensembl chr 8:108,271,666...108,282,919
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Siah2
siah E3 ubiquitin protein ligase 2
decreases expression
ISO
picene results in decreased expression of SIAH2 mRNA
CTD
PMID:32251684
NCBI chr 2:145,063,847...145,081,675
Ensembl chr 2:142,914,003...142,931,950
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Slc34a3
solute carrier family 34 member 3
increases expression
ISO
picene results in increased expression of SLC34A3 mRNA
CTD
PMID:32251684
NCBI chr 3:28,442,455...28,447,997
Ensembl chr 3:8,044,296...8,049,970
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Slc7a2
solute carrier family 7 member 2
decreases expression
ISO
picene results in decreased expression of SLC7A2 mRNA
CTD
PMID:32251684
NCBI chr16:58,115,991...58,174,256
Ensembl chr16:51,417,493...51,470,784
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Snora73b
small nucleolar RNA, H/ACA box 73b
increases expression
ISO
picene results in increased expression of SNORA73B mRNA
CTD
PMID:32251684
NCBI chr 5:149,829,190...149,829,393
Ensembl chr 5:144,545,179...144,545,382
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Stc2
stanniocalcin 2
increases expression
ISO
picene results in increased expression of STC2 mRNA
CTD
PMID:32251684
NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,250,853...16,262,973
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Tfap2c
transcription factor AP-2 gamma
decreases expression
ISO
picene results in decreased expression of TFAP2C mRNA
CTD
PMID:32251684
NCBI chr 3:181,733,524...181,742,412
Ensembl chr 3:161,315,031...161,322,995
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Tspear
thrombospondin-type laminin G domain and EAR repeats
increases expression
ISO
picene results in increased expression of TSPEAR mRNA
CTD
PMID:32251684
NCBI chr20:10,771,365...10,944,285
Ensembl chr20:10,772,219...10,943,914
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Wnt4
Wnt family member 4
decreases expression
ISO
picene results in decreased expression of WNT4 mRNA
CTD
PMID:32251684
NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859
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Xbp1
X-box binding protein 1
decreases expression
ISO
picene results in decreased expression of XBP1 mRNA
CTD
PMID:32251684
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
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