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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one
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Accession:CHEBI:32692 term browser browse the term
Definition:A nitrosamine that has formula C10H13N3O2.
Synonyms:exact_synonym: 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one
 related_synonym: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone;   4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone;   Formula=C10H13N3O2;   InChI=1S/C10H13N3O2/c1-13(12-15)7-3-5-10(14)9-4-2-6-11-8-9/h2,4,6,8H,3,5,7H2,1H3;   InChIKey=FLAQQSHRLBFIEZ-UHFFFAOYSA-N;   NNK;   NNK (carcinogen);   SMILES=CN(CCCC(=O)c1cccnc1)N=O
 xref: Beilstein:3548355;   CAS:64091-91-4;   KEGG:C16453
 xref_mesh: MESH:C016583


show annotations for term's descendants           Sort by:
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ABCB1B mRNA CTD PMID:14600272 PMID:23052194 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects abundance EXP ABCC2 protein affects the abundance of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone metabolite CTD PMID:17724374 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Aco1 aconitase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ACO1 mRNA CTD PMID:15890375 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of ACSL1 mRNA CTD PMID:20146248 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of AGPAT1 mRNA CTD PMID:20146248 NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278 		JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of AIF1 mRNA CTD PMID:14600272 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases metabolic processing ISO AKR1C1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:11306090 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases metabolic processing ISO AKR1C2 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:11306090 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of AKR7A3 mRNA CTD PMID:14600272 PMID:23052194 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of EIF4EBP1 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3A protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of AKT1 protein]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; methyllycaconitine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:12511591 PMID:34784199 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ALDH1A1 mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ALDH7A1 mRNA CTD PMID:19038236 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193 		JBrowse link
G Anxa2 annexin A2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ANXA2 mRNA CTD PMID:14600272 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of APEX1 mRNA CTD PMID:15890375 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of APH1B mRNA CTD PMID:22484513 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243 		JBrowse link
G Arid4b AT-rich interaction domain 4B multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of ARID4B mRNA CTD PMID:20146248 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906 		JBrowse link
G Asl argininosuccinate lyase increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ASL mRNA CTD PMID:19038236 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Atf1 activating transcription factor 1 increases phosphorylation
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein
Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]		 CTD PMID:16671086 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670 		JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ATF3 mRNA CTD PMID:15890375 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA] CTD PMID:21882252 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of ATP5MC1 mRNA CTD PMID:14600272 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ATP6V1D mRNA CTD PMID:14600272 PMID:22484513 PMID:23052194 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of B4GALT1 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of B4GALT1 mRNA] CTD PMID:21882252 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein
SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]		 CTD PMID:18508827 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Barhl1 BarH-like homeobox 1 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BARHL1 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BARHL1 mRNA] CTD PMID:21882252 NCBI chr 3:12,241,327...12,248,649
Ensembl chr 3:12,241,327...12,248,649 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases expression		 ISO
EXP		 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BAX mRNA; [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of BAX protein; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BAX mRNA]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BAX mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAX protein		 CTD PMID:14600272 PMID:15890375 PMID:21882252 PMID:22484513 PMID:23052194 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 ISO Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 mRNA]; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 protein		 CTD PMID:16582591 PMID:16835749 PMID:18508827 PMID:21776270 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BHMT mRNA CTD PMID:14600272 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
multiple interactions
increases expression 		ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein
SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein]; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein]
NNK increases expression of BIRC3 protein in nonsmall cell lung cancer cells		 CTD
RGD		 PMID:18508827 PMID:18508827 RGD:152998973 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BIRC5 mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of and results in increased expression of BIRC5 protein		 CTD PMID:21167638 PMID:21776270 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bola3 bolA family member 3 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BOLA3 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BOLA3 mRNA] CTD PMID:21882252 NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BRCA1 mRNA
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of BRCA1 mRNA		 CTD PMID:21167638 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BTG2 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BTG3 mRNA CTD PMID:22484513 PMID:23052194 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170 		JBrowse link
G Casp8 caspase 8 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CASP8 mRNA CTD PMID:21167638 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cbr1 carbonyl reductase 1 increases metabolic processing
multiple interactions		 ISO CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
Ethacrynic Acid inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Quercetin inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Rutin inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Vitamin K 3 inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]		 CTD PMID:11306090 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CCL2 protein CTD PMID:15762874 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CCNB1 mRNA CTD PMID:15890375 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression		 ISO
EXP		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK4 protein binds to CCND1 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK6 protein binds to CCND1 protein]; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; Benzamides analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; diphenyleneiodonium inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 protein		 CTD PMID:14600272 PMID:15890375 PMID:18805435 PMID:22484513 PMID:28321046 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCNE1 protein CTD PMID:30236600 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCNG1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCT3 mRNA CTD PMID:15890375 NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDC20 mRNA CTD PMID:15890375 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDH1 protein CTD PMID:30236600 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDH2 protein CTD PMID:30236600 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDK1 mRNA CTD PMID:15890375 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk16 cyclin-dependent kinase 16 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDK16 mRNA CTD PMID:15890375 NCBI chr  X:1,492,814...1,504,309
Ensembl chr  X:1,492,814...1,504,148 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
increases expression		 ISO
EXP		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK4 protein binds to CCND1 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDK4 mRNA		 CTD PMID:15890375 PMID:18805435 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK6 protein binds to CCND1 protein] CTD PMID:18805435 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
decreases expression		 ISO
EXP		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CDKN1A protein; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein]; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CDKN1A protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A mRNA		 CTD PMID:14600272 PMID:15890375 PMID:18508827 PMID:18805435 PMID:20421341 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1B protein
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1B protein]		 CTD PMID:18805435 PMID:30236600 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A mRNA; [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A protein CTD PMID:21167638 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CES2C mRNA CTD PMID:23052194 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CES2 mRNA CTD PMID:14600272 PMID:22484513 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CGREF1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852 		JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CGRRF1 mRNA CTD PMID:15890375 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CHD1L mRNA CTD PMID:19038236 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression
affects binding
increases activity		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CHRNA7 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone binds to CHRNA7 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CHRNA7 protein		 CTD PMID:16835749 PMID:17459420 PMID:19027725 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit multiple interactions ISO [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of CHRNA9 protein CTD PMID:30259641 NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192 		JBrowse link
G Cntn1 contactin 1 increases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CNTN1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CNTN1 mRNA]; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CNTN1 mRNA]		 CTD PMID:19027725 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of COL6A1 protein CTD PMID:23692979 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Commd1 copper metabolism domain containing 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of COMMD1 mRNA CTD PMID:19038236 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of COX17 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of COX17 mRNA] CTD PMID:21882252 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cr1l complement C3b/C4b receptor 1 like increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CR1L mRNA CTD PMID:15890375 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein
Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]		 CTD PMID:16671086 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cryab crystallin, alpha B increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CRYAB mRNA CTD PMID:14600272 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cstb cystatin B increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CSTB mRNA CTD PMID:15890375 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein]; wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTNNB1 protein] CTD PMID:28321046 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsd cathepsin D increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTSD mRNA CTD PMID:15890375 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctss cathepsin S increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTSS mRNA CTD PMID:14600272 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CXCL10 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO CYB5A protein promotes the reaction [CYP2A6 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:15728263 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CYB5R3 mRNA CTD PMID:14600272 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO
EXP		 [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of CYP1A1 mRNA; CYP1A1 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1A1 mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of CYP1A1 mRNA] CTD PMID:11774366 PMID:20146248 PMID:23052194 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases activity		 ISO CYP1A2 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP1A2 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone		 CTD PMID:11774366 PMID:15728263 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1B1 mRNA] CTD PMID:11774366 PMID:20146248 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions
affects metabolic processing
decreases hydroxylation
increases metabolic processing
increases activity
decreases metabolic processing
increases hydroxylation		 ISO [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone; [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-oxo-4-(3-pyridinebutanal); [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-oxo-4-(3-pyridyl)butanoic acid; CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; CYP2A13 protein promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; CYP2A13 protein results in increased metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; CYP2A13 protein results in increased metabolism of and results in increased susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; Methoxsalen inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Methoxsalen inhibits the reaction [CYP2A13 protein results in increased metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Metyrapone inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Miconazole inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Tranylcypromine inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]
CYP2A13 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP2A13 gene polymorphism results in decreased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP2A13 results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP2A13 protein SNP results in decreased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP2A13 protein results in increased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; CYP2A13 results in increased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone		 CTD PMID:12920169 PMID:14633739 PMID:15608128 PMID:16917071 PMID:17671098 More... NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity EXP CYP2B1 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:10799646 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
increases activity
multiple interactions		 ISO CYP2B6 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP2B6 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
[CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone		 CTD PMID:10799646 PMID:12920169 PMID:32672941 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP2C12 mRNA CTD PMID:22484513 PMID:23052194 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO CYP2C19 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:11774366 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:2070484 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing
increases activity
increases metabolic processing		 ISO
EXP		 CYP2E1 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CYP2E1 protein
CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone		 CTD PMID:9774145 PMID:12115524 PMID:12920169 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases metabolic processing		 ISO CYP3A4 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
CYP3A4 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone		 CTD PMID:9029045 PMID:11774366 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dapk1 death associated protein kinase 1 increases methylation ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased methylation of DAPK1 promoter CTD PMID:15172992 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dcn decorin increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DCN mRNA CTD PMID:14600272 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DDAH1 mRNA CTD PMID:15890375 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddx21 DExD-box helicase 21 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DDX21 mRNA CTD PMID:15890375 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:25451588 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases reduction ISO DHRS7 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:24246760 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKC1 mRNA CTD PMID:15890375
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]; Benzamides analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]; diphenyleneiodonium inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]; Wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA] CTD PMID:28321046 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DMBT1 mRNA CTD PMID:23052194 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of DPYD mRNA CTD PMID:15890375 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of DUSP6 mRNA CTD PMID:15890375 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DUT mRNA CTD PMID:15890375 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EEF1G mRNA CTD PMID:15890375 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EEF2 mRNA CTD PMID:15890375 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Egfr epidermal growth factor receptor increases phosphorylation
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein
Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein]		 CTD PMID:16671086 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression
multiple interactions		 EXP
ISO		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EIF4EBP1 mRNA
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of EIF4EBP1 protein		 CTD PMID:12511591 PMID:15890375 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EPHX1 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fam162a family with sequence similarity 162, member A increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FAM162A mRNA CTD PMID:15890375 NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239 		JBrowse link
G Fasn fatty acid synthase increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FASN protein CTD PMID:18413838 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 protein
NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 protein]		 CTD PMID:35435490 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FKBP4 mRNA CTD PMID:15890375 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Fn1 fibronectin 1 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FN1 mRNA CTD PMID:15890375 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FOS mRNA
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of FOS mRNA		 CTD PMID:21167638 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxp1 forkhead box P1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FOXP1 mRNA alternative form CTD PMID:35435490 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of FTH1 mRNA CTD PMID:20146248 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of FXYD3 mRNA CTD PMID:20146248 NCBI chr 1:86,305,531...86,312,455 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GADD45A mRNA CTD PMID:15890375 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GAS6 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions
increases activity
increases expression		 ISO Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GATA3 mRNA		 CTD PMID:16582591 PMID:16835749 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GCLC mRNA CTD PMID:15890375 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GDF15 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gls2 glutaminase 2 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GLS2 mRNA CTD PMID:14600272 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GNMT mRNA CTD PMID:14600272 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GRIA3 mRNA CTD PMID:22484513 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GRPEL1 mRNA CTD PMID:15890375 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3A protein CTD PMID:12511591 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein CTD PMID:12511591 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSR mRNA CTD PMID:15890375 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSS mRNA CTD PMID:15890375 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSTA2 mRNA CTD PMID:15890375 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression
increases activity
increases expression		 EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GSTA4 mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GSTA4 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSTA4 mRNA		 CTD PMID:9774145 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSTA5 mRNA CTD PMID:14600272 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gtpbp1 GTP binding protein 1 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GTPBP1 mRNA CTD PMID:19038236 NCBI chr 7:111,248,254...111,272,705
Ensembl chr 7:111,248,254...111,272,705 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
increases expression		 ISO
EXP		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of H2AX protein; Caffeine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of H2AX protein]; CYP2A13 protein promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; methyllycaconitine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein modified form]; Wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein modified form		 CTD PMID:15890375 PMID:21882252 PMID:26231820 PMID:34784199 PMID:35435490 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G H2az1 H2A.Z variant histone 1 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of H2AZ1 mRNA CTD PMID:15890375 NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485 		JBrowse link
G H3f4 H3.4 histone, cluster member increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H3-4 mRNA CTD PMID:19038236 NCBI chr10:43,740,702...43,741,262 JBrowse link
G Hba-a3 hemoglobin alpha, adult chain 3 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HBA2 mRNA CTD PMID:20146248 NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481 		JBrowse link
G Hcrtr2 hypocretin receptor 2 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HCRTR2 mRNA CTD PMID:19038236 NCBI chr 8:76,989,834...77,105,953
Ensembl chr 8:76,989,834...77,105,893 		JBrowse link
G Hdc histidine decarboxylase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HDC mRNA CTD PMID:15890375 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions
increases expression		 ISO 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HES1 mRNA] CTD PMID:28321046 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of HMGB2 mRNA CTD PMID:15890375 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein]; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 mRNA		 CTD PMID:15890375 PMID:18508827 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions
increases mutagenesis		 ISO [Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene; Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene		 CTD PMID:15613823 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions
increases reduction		 ISO drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Ethinyl Estradiol inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Progesterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Testosterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:28257955 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA; Grape Seed Proanthocyanidins inhibits the reaction [[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA] CTD PMID:20146248 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSF1 mRNA CTD PMID:15890375 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPA9 mRNA CTD PMID:15890375 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPB1 mRNA CTD PMID:15890375 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPE1 mRNA CTD PMID:15890375 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPH1 mRNA CTD PMID:15890375 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Ide insulin degrading enzyme increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IDE mRNA CTD PMID:15890375 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IGFBP1 mRNA CTD PMID:15890375 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IGFBP2 mRNA CTD PMID:22484513 PMID:23052194 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of IGFBP3 mRNA CTD PMID:15890375 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il6 interleukin 6 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of IL6 protein CTD PMID:15762874 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of INMT mRNA CTD PMID:22484513 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493 		JBrowse link
G Ints4 integrator complex subunit 4 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of INTS4 mRNA CTD PMID:22484513 NCBI chr 1:151,790,062...151,853,827
Ensembl chr 1:151,786,553...151,853,827 		JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IRF1 mRNA CTD PMID:14600272 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of JUN mRNA
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of JUN mRNA		 CTD PMID:21167638 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis
multiple interactions		 EXP
ISO		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of KRAS gene
[Lipopolysaccharides co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of KRAS gene		 CTD PMID:18271921 PMID:21868532 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt15 keratin 15 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of KRT15 mRNA CTD PMID:20146248 NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lama5 laminin subunit alpha 5 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of LAMA5 mRNA CTD PMID:22484513 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451 		JBrowse link
G Lgals3 galectin 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of LGALS3 mRNA CTD PMID:15890375 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Ltb4r leukotriene B4 receptor decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of LTB4R mRNA CTD PMID:19038236 NCBI chr15:29,263,199...29,265,716 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K1 protein; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K1 protein] CTD PMID:21882252 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein] CTD PMID:21882252 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
increases activity		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of MAPK1 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK1 protein; [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of MAPK1 protein; Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of MAPK1 protein		 CTD PMID:15603589 PMID:16671086 PMID:17459420 PMID:18508827 PMID:21882252 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
increases phosphorylation
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of MAPK3 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of MAPK3 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK3 protein; [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of MAPK3 protein; Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]		 CTD PMID:15603589 PMID:16671086 PMID:17459420 PMID:18508827 PMID:21882252 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MAT1A mRNA CTD PMID:14600272 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MCAM mRNA CTD PMID:21167638 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MCM6 mRNA CTD PMID:15890375 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MGMT mRNA CTD PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mir155 microRNA 155 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MIR155 mRNA CTD PMID:32326378 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir21 microRNA 21 multiple interactions
increases expression		 ISO MIR21 mRNA affects the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MSH2 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MIR21 mRNA		 CTD PMID:32326378 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mis18a MIS18 kinetochore protein A increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MIS18A mRNA CTD PMID:19038236 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MKI67 protein CTD PMID:21776270 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MLH1 mRNA CTD PMID:32326378 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MMP9 mRNA
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of MMP9 mRNA		 CTD PMID:21167638 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MRPL41 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MRPL41 mRNA] CTD PMID:21882252 NCBI chr 3:7,780,658...7,781,576
Ensembl chr 3:7,779,143...7,782,818 		JBrowse link
G Msh2 mutS homolog 2 multiple interactions
decreases expression		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of and affects the localization of MSH2 protein; MIR21 mRNA affects the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MSH2 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MSH2 mRNA		 CTD PMID:32326378 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Mt1 metallothionein 1 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MT1E mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MT1E mRNA] CTD PMID:21882252 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Mt2A metallothionein 2A decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT2 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT2A mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mta2 metastasis associated 1 family, member 2 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MTA2 mRNA CTD PMID:21167638 NCBI chr 1:205,838,181...205,846,903
Ensembl chr 1:205,837,964...205,846,946 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases activity
increases expression		 ISO
EXP		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of MYC protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MYC mRNA		 CTD PMID:15890375 PMID:17459420 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nanog Nanog homeobox increases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NANOG protein
[Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of NANOG protein		 CTD PMID:30259641 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NAP1L1 mRNA CTD PMID:15890375 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
increases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA
Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA]; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein]		 CTD PMID:16582591 PMID:16835749 PMID:18508827 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of NFKBIA protein CTD PMID:18508827 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nhej1 nonhomologous end-joining factor 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NHEJ1 mRNA CTD PMID:22484513 NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444 		JBrowse link
G Nipbl NIPBL, cohesin loading factor multiple interactions
increases response to substance
increases expression		 ISO NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein modified form]
NIPBL mRNA alternative form results in increased susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NIPBL mRNA alternative form		 CTD PMID:35435490 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NPC1 mRNA CTD PMID:19038236 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NPM1 mRNA CTD PMID:15890375 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NQO1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NRCAM mRNA CTD PMID:22484513 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrg1 neuregulin 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NRG1 mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nubpl NUBP iron-sulfur cluster assembly factor like decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of NUBPL mRNA CTD PMID:22484513 NCBI chr 6:69,559,278...69,781,254
Ensembl chr 6:69,559,291...69,781,253 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of NUPR1 mRNA CTD PMID:15890375 PMID:23052194 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Oat ornithine aminotransferase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of OAT mRNA CTD PMID:14600272 PMID:22484513 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Obp1f odorant binding protein I f increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of OBP1F mRNA CTD PMID:22484513 NCBI chr  X:41,955,618...41,960,681
Ensembl chr  X:41,955,618...41,960,681 		JBrowse link
G Obp3 alpha-2u globulin PGCL4 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of OBP3 mRNA CTD PMID:15890375 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757 		JBrowse link
G Ocln occludin decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of OCLN protein CTD PMID:30236600 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity
increases expression
multiple interactions		 ISO
EXP		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of ODC1 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ODC1 mRNA
tocopheryloxybutyric acid inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of ODC1 protein]; tocopheryloxybutyric acid inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ODC1 mRNA]		 CTD PMID:11301052 PMID:15890375 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases expression		 ISO NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein		 CTD PMID:35435490 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
decreases expression		 ISO
EXP		 Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PCNA mRNA]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA protein		 CTD PMID:15890375 PMID:16582591 PMID:16835749 PMID:35435490 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of PCSK2 mRNA CTD PMID:20146248 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Per1 period circadian regulator 1 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of PER1 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of PER1 mRNA] CTD PMID:21882252 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PGD mRNA CTD PMID:19038236 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PHGDH mRNA CTD PMID:15890375 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PHLDA3 mRNA CTD PMID:22484513 PMID:23052194 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLA2G2A mRNA CTD PMID:24835565 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLA2G4A mRNA CTD PMID:24835565 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plau plasminogen activator, urokinase decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PLAU mRNA
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of PLAU mRNA		 CTD PMID:21167638 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plk2 polo-like kinase 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLK2 mRNA CTD PMID:23052194 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Pln phospholamban increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLN mRNA CTD PMID:22484513 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Por cytochrome p450 oxidoreductase affects response to substance ISO POR affects the susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:22710403 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Prdx6 peroxiredoxin 6 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PRDX6 protein CTD PMID:23692979 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA1 mRNA CTD PMID:15890375 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA2 mRNA CTD PMID:15890375 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938 		JBrowse link
G Psma4 proteasome 20S subunit alpha 4 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA4 mRNA CTD PMID:15890375 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PSMA5 mRNA CTD PMID:15890375 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731 		JBrowse link
G Psma7 proteasome 20S subunit alpha 7 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA7 mRNA CTD PMID:15890375 NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB1 mRNA CTD PMID:15890375 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560 		JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB3 mRNA CTD PMID:15890375 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521 		JBrowse link
G Psmb4 proteasome 20S subunit beta 4 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB4 mRNA CTD PMID:15890375 NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB5 mRNA CTD PMID:15890375 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC1 mRNA CTD PMID:15890375 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC2 mRNA CTD PMID:15890375 NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC4 mRNA CTD PMID:15890375 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC5 mRNA CTD PMID:15890375 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMD1 mRNA CTD PMID:15890375 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases activity		 ISO [4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased abundance of Dinoprostone]; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; Propranolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; SB 203580 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein] CTD PMID:15762874 PMID:18805435 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of PTK2 protein CTD PMID:30259641 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PTP4A1 mRNA CTD PMID:15890375 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PTTG1 mRNA CTD PMID:15890375 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G R3hdm2 R3H domain containing 2 decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of R3HDM2 mRNA CTD PMID:22484513 NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540 		JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RAD23B mRNA CTD PMID:19038236 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase increases activity ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of RAF1 protein CTD PMID:17459420 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rarb retinoic acid receptor, beta increases methylation ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased methylation of RARB promoter CTD PMID:14656941 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases phosphorylation
decreases expression		 ISO
EXP		 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RB1 mRNA		 CTD PMID:15890375 PMID:18805435 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of RELA protein CTD PMID:18508827 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rfx1 regulatory factor X1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RFX1 mRNA CTD PMID:19038236 NCBI chr19:24,061,336...24,092,044
Ensembl chr19:24,061,336...24,092,044 		JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b multiple interactions ISO [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of RGMB mRNA CTD PMID:20146248 NCBI chr 1:56,766,598...56,792,396
Ensembl chr 1:56,767,850...56,792,425 		JBrowse link
G Rhcg Rh family, C glycoprotein decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RHCG mRNA CTD PMID:19038236 NCBI chr 1:133,531,704...133,555,902
Ensembl chr 1:133,531,716...133,555,876 		JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RHEB mRNA CTD PMID:15890375 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Rhob ras homolog family member B increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RHOB mRNA CTD PMID:14600272 PMID:22484513 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Rpl10 ribosomal protein L10 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL10 mRNA CTD PMID:15890375 NCBI chr  X:152,054,562...152,056,769
Ensembl chr  X:152,054,452...152,056,761 		JBrowse link
G Rpl10a ribosomal protein L10A increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL10A mRNA CTD PMID:15890375 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
Ensembl chr 9:6,385,823...6,391,357 		JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL13 mRNA CTD PMID:15890375 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014 		JBrowse link
G Rpl15 ribosomal protein L15 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL15 mRNA CTD PMID:15890375 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
Ensembl chr12:7,503,883...7,507,165 		JBrowse link
G Rpl17 ribosomal protein L17 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL17 mRNA CTD PMID:15890375 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
Ensembl chr 3:68,581,098...68,584,253 		JBrowse link
G Rpl23 ribosomal protein L23 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL23 mRNA CTD PMID:15890375 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870 		JBrowse link
G Rpl6 ribosomal protein L6 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL6 mRNA CTD PMID:15890375 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921 		JBrowse link
G Rpl7a ribosomal protein L7A increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL7A mRNA CTD PMID:15890375 NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
Ensembl chr18:10,239,001...10,241,716 		JBrowse link
G Rpl8 ribosomal protein L8 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL8 mRNA CTD PMID:15890375 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482 		JBrowse link
G Rps15a ribosomal protein S15a increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS15A mRNA CTD PMID:15890375 NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995 		JBrowse link
G Rps19 ribosomal protein S19 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS19 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508 		JBrowse link
G Rps24 ribosomal protein S24 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS24 mRNA CTD PMID:15890375 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279 		JBrowse link
G Rps27l ribosomal protein S27-like increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS27L mRNA CTD PMID:15890375 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
Ensembl chr12:67,562,483...67,567,418
Ensembl chr 2:67,562,483...67,567,418 		JBrowse link
G Rps3 ribosomal protein S3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS3 mRNA CTD PMID:15890375 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Rps4x ribosomal protein S4, X-linked increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS4X mRNA CTD PMID:15890375 NCBI chr  X:67,298,522...67,302,965
Ensembl chr  X:67,298,525...67,303,019
Ensembl chr 4:67,298,525...67,303,019 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
increases phosphorylation		 ISO [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RPS6KB1 protein		 CTD PMID:30259641 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rps7 ribosomal protein S7 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS7 mRNA CTD PMID:15890375 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145 		JBrowse link
G Rpsa ribosomal protein SA increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPSA mRNA CTD PMID:15890375 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RT1-BB mRNA CTD PMID:14600272 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of S100A4 mRNA
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of S100A4 mRNA		 CTD PMID:21167638 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G Sds serine dehydratase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SDS mRNA CTD PMID:14600272 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203 		JBrowse link
G Selenoo selenoprotein O increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SELENOO mRNA CTD PMID:19038236 NCBI chr 7:120,167,913...120,178,806
Ensembl chr 7:120,167,913...120,178,805 		JBrowse link
G Selenow selenoprotein W increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SELENOW mRNA CTD PMID:15890375 NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724 		JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SERPINA7 mRNA CTD PMID:14600272 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A2 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A2 protein
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A2 protein] which results in decreased uptake of Thiamine		 CTD PMID:24244374 NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172 		JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions
decreases expression		 ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A3 protein] which results in decreased uptake of Thiamine
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A3 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A3 protein		 CTD PMID:24244374 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337 		JBrowse link
G Slc9a9 solute carrier family 9 member A9 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC9A9 mRNA CTD PMID:19038236 NCBI chr 8:95,232,889...95,797,262
Ensembl chr 8:95,232,905...95,796,318 		JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SMG1 mRNA CTD PMID:19038236 NCBI chr 1:172,441,892...172,543,667
Ensembl chr 1:172,444,936...172,543,698 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SMOC1 mRNA CTD PMID:19038236 NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699 		JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SNAI2 protein CTD PMID:30236600 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Soat2 sterol O-acyltransferase 2 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SOAT2 mRNA CTD PMID:19038236 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915 		JBrowse link
G Sprr1b small proline-rich protein 1B multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of SPRR1B mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of SPRR1B mRNA] CTD PMID:21882252 NCBI chr 2:178,008,844...178,010,742
Ensembl chr 2:178,009,130...178,009,567 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SPTAN1 mRNA CTD PMID:14600272 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases activity
increases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STAT1 mRNA
Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STAT1 mRNA]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]		 CTD PMID:16582591 PMID:16835749 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stmn1 stathmin 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STMN1 mRNA CTD PMID:15890375 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TAP1 mRNA CTD PMID:14600272 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tars1 threonyl-tRNA synthetase 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TARS1 mRNA CTD PMID:19038236 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717 		JBrowse link
G Tat tyrosine aminotransferase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TAT mRNA CTD PMID:15890375 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tbrg4 transforming growth factor beta regulator 4 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TBRG4 mRNA CTD PMID:19038236 NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756 		JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TIMM10B mRNA CTD PMID:15890375 NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
Ensembl chr20:159,980,484...159,981,642 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TIMP1 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tmsb10 thymosin, beta 10 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TMSB10 mRNA CTD PMID:14600272 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions ISO [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in decreased expression of TNFRSF8 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in decreased expression of TNFRSF8 mRNA] CTD PMID:21882252 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TOP2A mRNA CTD PMID:15890375 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
affects localization
decreases expression
increases phosphorylation
increases ADP-ribosylation
increases expression		 ISO 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite affects the localization of TP53 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite results in increased activity of TP53 protein]
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of TP53 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased ADP-ribosylation of TP53 protein
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of TRP53 mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein		 CTD PMID:18805435 PMID:19931552 PMID:20421341 PMID:21167638 PMID:21776270 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53BP1 protein CTD PMID:26231820 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Tpd52 tumor protein D52 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression EXP
ISO		 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TSC22D1 mRNA
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TSC22 mRNA		 CTD PMID:15890375 PMID:19038236 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Tuba1c tubulin, alpha 1C increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TUBA1C mRNA CTD PMID:15890375 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TUBB5 mRNA CTD PMID:15890375 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TWIST1 mRNA CTD PMID:21167638 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Tyms thymidylate synthetase increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TYMS mRNA CTD PMID:14600272 PMID:15890375 PMID:23052194 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of UBA52 mRNA CTD PMID:19038236 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807 		JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 increases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of UBE2R2 mRNA CTD PMID:19038236 NCBI chr 5:56,286,604...56,345,160
Ensembl chr 5:56,286,725...56,345,513 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 gene polymorphism results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; UGT1A4 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:14871856 PMID:31307193 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of UGT1A7 mRNA CTD PMID:14600272 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:31307193 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases glucuronidation ISO UGT2B17 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:31307193 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases glucuronidation
increases glucuronidation		 ISO UGT2B7 gene polymorphism results in decreased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
UGT2B7 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone		 CTD PMID:14871856 PMID:31307193 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of VEGFA mRNA CTD PMID:15890375 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vim vimentin increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of VIM mRNA CTD PMID:14600272 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Xdh xanthine dehydrogenase decreases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XDH mRNA CTD PMID:15890375 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of XIAP protein
[Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of XIAP protein		 CTD PMID:30259641 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Xpo1 exportin 1 decreases expression ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XPO1 protein CTD PMID:20421341 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression
multiple interactions		 ISO 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 protein
NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 protein]		 CTD PMID:35435490 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression EXP 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ZMAT3 mRNA CTD PMID:14600272 PMID:15890375 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      group 19831
        inorganic group 19410
          nitroso group 5066
            nitroso compound 5066
              nitrosamine 3801
                4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one 309
                  4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteromonocyclic compound 17795
                                    pyridines 11518
                                      4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one 309
                                        4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol 0
paths to the root