CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: magnesium sulfate
Accession: CHEBI:32599
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Definition: A magnesium salt having sulfate as the counterion.
Synonyms: related_synonym: Formula=MgO4S; InChI=1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2; InChIKey=CSNNHWWHGAXBCP-UHFFFAOYSA-L; Magnesium sulfate (1:1); Magnesiumsulfat; MgSO4; SMILES=[Mg++].[O-]S([O-])(=O)=O; magnesium sulfate anhydrous; magnesium sulphate; magnesium(II) sulfate; sulfuric acid magnesium salt; sulphate of magnesia
xref: CAS:7487-88-9; DrugBank:DB00653
xref_mesh: MESH:D008278
xref: PMID:10723972; PMID:11251702; PMID:15357561; PMID:19805935; PMID:31092073; PMID:31412352; PMID:32063925; PMID:32256123; PMID:8991630; Reaxys:4208125
G
Bche
butyrylcholinesterase
multiple interactions
EXP
Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein]
CTD
PMID:19504058
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
G
Cat
catalase
multiple interactions decreases activity
EXP
Magnesium Sulfate promotes the reaction [Vanadates results in decreased activity of CAT protein] Magnesium Sulfate results in decreased activity of CAT protein
CTD
PMID:29117755 PMID:29453945
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Gpx1
glutathione peroxidase 1
decreases activity
EXP
Magnesium Sulfate results in decreased activity of GPX1 protein
CTD
PMID:29117755
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gsr
glutathione-disulfide reductase
decreases activity multiple interactions
EXP
Magnesium Sulfate results in decreased activity of GSR protein [Magnesium Sulfate co-treated with Vanadates] results in decreased activity of GSR protein
CTD
PMID:29453945
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Il1b
interleukin 1 beta
decreases expression
ISO
Magnesium Sulfate results in decreased expression of IL1B mRNA
CTD
PMID:29594315
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Kcnc2
potassium voltage-gated channel subfamily C member 2
decreases expression
EXP
Magnesium Sulfate results in decreased expression of KCNC2 mRNA; Magnesium Sulfate results in decreased expression of KCNC2 protein
CTD
PMID:18775767
NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
G
Klk8
kallikrein related-peptidase 8
increases activity
ISO
Magnesium Sulfate results in increased activity of KLK8 protein
CTD
PMID:16800733
NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
G
Ren
renin
increases activity
ISO
Magnesium Sulfate results in increased activity of REN protein
CTD
PMID:1874207
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Sod1
superoxide dismutase 1
decreases activity
EXP
Magnesium Sulfate results in decreased activity of SOD1 protein
CTD
PMID:29117755
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Trpm5
transient receptor potential cation channel, subfamily M, member 5
affects response to substance
ISO
TRPM5 protein affects the susceptibility to Magnesium Sulfate
CTD
PMID:19244541
NCBI chr 1:198,254,956...198,277,824
Ensembl chr 1:198,255,723...198,277,654
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