Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butamben
go back to main search page
Accession:CHEBI:3231 term browser browse the term
Definition:An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders.
Synonyms:exact_synonym: butyl 4-aminobenzoate
 related_synonym: 4-(butoxycarbonyl)aniline;   4-aminobenzoic acid butyl ester;   BAB;   Butesin;   Butoform;   Formula=C11H15NO2;   InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3;   InChIKey=IUWVALYLNVXWKX-UHFFFAOYSA-N;   Planoform;   SMILES=CCCCOC(=O)c1ccc(N)cc1;   Scuroform;   Scuroforme;   butyl aminobenzoate;   butyl p-aminobenzoate;   n-butyl p-aminobenzoate;   p-aminobenzoic acid butyl ester
 xref: CAS:94-25-7;   Drug_Central:3051;   KEGG:C07875;   KEGG:D00730;   LINCS:LSM-5413
 xref_mesh: MESH:C004605
 xref: PMID:15920194;   PMID:15923341;   PMID:16368819;   PMID:18499609;   PMID:22133806;   PMID:2393134;   PMID:24486399;   PMID:7793660;   PMID:9009953;   PMID:9690593;   Patent:GB252870;   Patent:US1440652;   Reaxys:1211465;   Wikipedia:Butamben
 cyclic_relationship: is_conjugate_base_of CHEBI:86302


show annotations for term's descendants           Sort by:
butamben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP butamben binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to MED1 protein]; butamben promotes the reaction [NR1I2.S protein binds to MED1 protein] CTD PMID:12198127 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA1 protein]; butamben promotes the reaction [NR1I2.S protein binds to NCOA1 protein] CTD PMID:12198127 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA2 protein] CTD PMID:12198127 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA3 protein] CTD PMID:12198127 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        aetiopathogenetic role 19237
          allergen 17708
            4-aminobenzoic acid 31
              butamben 5
                butamben picrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            heteroorganic entity 19556
                              organochalcogen compound 19315
                                organooxygen compound 19205
                                  carbon oxoacid 18694
                                    carboxylic acid 18691
                                      monocarboxylic acid 18007
                                        fatty acid 16847
                                          fatty acid derivative 8975
                                            fatty alcohol 6131
                                              primary fatty alcohol 5794
                                                short-chain primary fatty alcohol 5785
                                                  butan-1-ol 5727
                                                    butamben 5
                                                      butamben picrate 0
paths to the root