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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tenoxicam
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Accession:CHEBI:32192 term browser browse the term
Definition:A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries.
Synonyms:exact_synonym: 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
 related_synonym: Formula=C13H11N3O4S2;   InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18);   InChIKey=LZNWYQJJBLGYLT-UHFFFAOYSA-N;   Mobiflex;   SMILES=CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O;   Tilcotil;   tenoxicamum
 xref: CAS:59804-37-4;   DrugBank:DB00469;   Drug_Central:2595;   KEGG:D01767
 xref_mesh: MESH:C032801
 xref: PMID:21129461;   PMID:21327813;   PMID:21682312;   PMID:21712619;   PMID:21777594;   PMID:21929527;   PMID:21981557;   PMID:22095696;   PMID:22182582;   PMID:22306394;   PMID:22675955;   PMID:22841852;   PMID:22876956;   PMID:23204620;   PMID:23273940;   PMID:23340327;   PMID:23480456;   PMID:23656309;   PMID:23932198;   PMID:24037655;   PMID:24093711;   PMID:28166217;   Patent:US2008014272;   Patent:US4687766;   Reaxys:572193;   Wikipedia:Tenoxicam


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tenoxicam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO tenoxicam inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        anti-inflammatory agent 16666
          anti-inflammatory drug 14958
            non-steroidal anti-inflammatory drug 14274
              tenoxicam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      carboacyl group 17694
                                        univalent carboacyl group 17694
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              monocarboxylic acid amide 15727
                                                tenoxicam 1
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