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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sucralose
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Accession:CHEBI:32159 term browser browse the term
Definition:A disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond.
Synonyms:exact_synonym: 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactopyranoside
 related_synonym: Formula=C12H19Cl3O8;   InChI=1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1;   InChIKey=BAQAVOSOZGMPRM-QBMZZYIRSA-N;   SMILES=OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl;   Trichlorosucrose
 xref: CAS:56038-13-2;   HMDB:HMDB0031554;   KEGG:C12285
 xref_mesh: MESH:C026285
 xref: PMID:24687789;   PMID:25236212;   Reaxys:3654410;   Wikipedia:Sucralose


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sucralose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gast gastrin increases secretion EXP trichlorosucrose results in increased secretion of GAST protein CTD PMID:19208342 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Tas1r2 taste 1 receptor member 2 multiple interactions
affects binding		 ISO trichlorosucrose results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
trichlorosucrose binds to TAS1R2 protein		 CTD PMID:20173092 PMID:20302879 NCBI chr 5:151,909,617...151,925,760
Ensembl chr 5:151,830,701...151,925,345 		JBrowse link
G Tas1r3 taste 1 receptor member 3 multiple interactions
affects binding		 ISO trichlorosucrose results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
trichlorosucrose binds to TAS1R3 protein		 CTD PMID:20173092 PMID:20302879 NCBI chr 5:166,468,703...166,472,759
Ensembl chr 5:166,469,589...166,472,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        xenobiotic 18728
          sucralose 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbohydrates and carbohydrate derivatives 15289
                                    carbohydrate 15289
                                      oligosaccharide 626
                                        disaccharide 531
                                          disaccharide derivative 469
                                            sucralose 3
paths to the root