CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: sodium hypochlorite
Accession: CHEBI:32146
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Definition: An inorganic sodium salt in which hypochlorite is the counterion. It is used as a bleaching and disinfecting agent and is commonly found in household bleach.
Synonyms: related_synonym: Formula=ClNaO; Hypochlorous acid, sodium salt; InChI=1S/ClO.Na/c1-2;/q-1;+1; InChIKey=SUKJFIGYRHOWBL-UHFFFAOYSA-N; NaClO; NaOCl; SMILES=[Na+].[O-]Cl; Sodium oxychloride; Texant
xref: AGR:IND606841968; CAS:7681-52-9; DrugBank:DBSALT001517; FooDB:FDB015395; KEGG:D01711
xref_mesh: MESH:D012973
xref: PMID:19707590; PMID:23011474; PMID:23355285; PMID:23701220; PMID:23710836; PMID:23892500; PMID:24308707; PMID:24331991; PMID:24417739; PMID:24554854; PMID:24554863; PMID:24701613; PMID:24717113; PMID:24784510; PMID:24862721; PMID:30689457; PMID:32336370; PMID:32414067; PPDB:1493; Reaxys:11342986; Wikipedia:Sodium_hypochlorite
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Alpl
alkaline phosphatase, biomineralization associated
increases expression
ISO
Sodium Hypochlorite results in increased expression of ALPL mRNA
CTD
PMID:22083529
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Atf3
activating transcription factor 3
increases expression
ISO
Sodium Hypochlorite results in increased expression of ATF3 mRNA
CTD
PMID:37149095
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Ccl2
C-C motif chemokine ligand 2
decreases expression
ISO
Sodium Hypochlorite results in decreased expression of CCL2 mRNA
CTD
PMID:37149095
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Csrnp1
cysteine and serine rich nuclear protein 1
increases expression
ISO
Sodium Hypochlorite results in increased expression of CSRNP1 mRNA
CTD
PMID:37149095
NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
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Esr2
estrogen receptor 2
multiple interactions
ISO
Sodium Hypochlorite inhibits the reaction [bisphenol A binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [Estradiol binds to ESR2 protein]; Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein]
CTD
PMID:14723943
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Sodium Hypochlorite results in increased expression of FOSB mRNA
CTD
PMID:37149095
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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Hmox1
heme oxygenase 1
increases expression
ISO
Sodium Hypochlorite results in increased expression of HMOX1 mRNA
CTD
PMID:37149095
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression
ISO
Sodium Hypochlorite results in decreased expression of HSD3B1 mRNA
CTD
PMID:37149095
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
ISO
Sodium Hypochlorite results in increased expression of HSPA1A mRNA
CTD
PMID:37149095
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
Sodium Hypochlorite results in increased expression of HSPA1B mRNA
CTD
PMID:37149095
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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Ifna1
interferon, alpha 1
increases expression
ISO
Sodium Hypochlorite results in increased expression of IFNA1 mRNA
CTD
PMID:37149095
NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925
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Il24
interleukin 24
increases expression
ISO
Sodium Hypochlorite results in increased expression of IL24 mRNA
CTD
PMID:37149095
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Sodium Hypochlorite results in increased expression of JUNB mRNA
CTD
PMID:37149095
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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LOC120102574
U6 spliceosomal RNA
increases expression
ISO
Sodium Hypochlorite results in increased expression of RNU6-1014P
CTD
PMID:37149095
NCBI chr 4:102,735,624...102,735,728
Ensembl chr 4:102,735,624...102,735,728
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Mpo
myeloperoxidase
multiple interactions
ISO
Sodium Hypochlorite promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Sodium Hypochlorite promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]
CTD
PMID:25614581
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
Sodium Hypochlorite results in increased expression of NR4A1 mRNA
CTD
PMID:37149095
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
ISO
Sodium Hypochlorite results in increased expression of NR4A2 mRNA
CTD
PMID:37149095
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
Sodium Hypochlorite results in increased expression of NR4A3 mRNA
CTD
PMID:37149095
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
Sodium Hypochlorite results in increased expression of PPP1R15A mRNA
CTD
PMID:37149095
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Slc7a11
solute carrier family 7 member 11
increases expression
ISO
Sodium Hypochlorite results in increased expression of SLC7A11 mRNA
CTD
PMID:37149095
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Spry2
sprouty RTK signaling antagonist 2
increases expression
ISO
Sodium Hypochlorite results in increased expression of SPRY2 mRNA
CTD
PMID:37149095
NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009
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