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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:midodrine hydrochloride
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Accession:CHEBI:31847 term browser browse the term
Definition:A hydrochloride resulting from the combination of equimolar amounts of midodrine and hydrogen chloride. Midodrine is a direct-acting sympathomimetic with selective alpha-adrenergic agonist activity. The hydrochloride salt is used as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
Synonyms:exact_synonym: rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide hydrochloride
 related_synonym: (+-)-1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride;   (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide monohydrochloride;   Formula=C12H18N2O4.HCl;   Formula=C12H19ClN2O4;   InChI=1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H;   InChIKey=MGCQZNBCJBRZDT-UHFFFAOYSA-N;   Midodrine HCl;   Pro-Amatine;   ProAmatine;   SMILES=Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
 xref: CAS:3092-17-9;   DrugBank:DB00211;   HMDB:HMDB0014356;   KEGG:D01307;   PMID:20801263;   PMID:21301135;   Patent:WO2004018409;   Reaxys:6579688


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Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      application 19713
        pharmaceutical 19548
          drug 19548
            cardiovascular drug 8654
              vasoconstrictor agent 2042
                midodrine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      halogen 18703
                        chlorine atom 18489
                          chlorine molecular entity 18489
                            elemental chlorine 8796
                              monoatomic chlorine 8781
                                chloride 8781
                                  chloride salt 8781
                                    organic chloride salt 1107
                                      hydrochloride 738
                                        midodrine hydrochloride 0
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