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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:mercury dichloride
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Accession:CHEBI:31823 term browser browse the term
Definition:A mercury coordination entity made up of linear triatomic molecules in which a mercury atom is bonded to two chlorines. Water-soluble, it is highly toxic. Once used in a wide variety of applications, including preserving wood and anatomical specimens, embalming and disinfecting, as an intensifier in photography, as a mordant for rabbit and beaver furs, and freeing gold from lead, its use has markedly declined as less toxic alternatives have been developed.
Synonyms:exact_synonym: mercury(2+) chloride
 related_synonym: ClHgCl;   Formula=Cl2Hg;   HgCl2;   InChI=1S/2ClH.Hg/h2*1H;/q;;+2/p-2;   InChIKey=LWJROJCJINYWOX-UHFFFAOYSA-L;   Mercuric chloride;   Mercury(II) chloride;   Quecksilber(II)-chlorid;   SMILES=Cl[Hg]Cl;   Sublimat;   Sulema;   bichlorure de mercure;   chlorure mercurique;   corrosive mercury chloride;   corrosive sublimate;   dichloromercury;   dichlorure de mercure;   hydrargyrum bichloratum;   mercuric bichloride;   mercury bichloride;   mercury perchloride;   perchloride of mercury;   sublimate
 xref: CAS:7487-94-7;   Drug_Central:4787;   Gmelin:100830;   KEGG:C13377;   KEGG:D01905
 xref_mesh: MESH:D008627
 xref: PMID:25042713;   PMID:29079364;   PMID:7980848;   PMID:8991630;   Reaxys:4937255


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mercury dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) multiple interactions EXP Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water] CTD PMID:16534851 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G ATF4 activating transcription factor 4 increases expression EXP Mercuric Chloride results in increased expression of ATF4 protein CTD PMID:16759985 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation EXP Mercuric Chloride results in increased phosphorylation of EIF2A protein CTD PMID:16759985 NCBI chr13:90,761,453...90,804,274
Ensembl chr13:90,761,465...90,804,274 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of FOS mRNA]
Mercuric Chloride results in increased expression of FOS mRNA; Mercuric Chloride results in increased expression of FOS protein		 CTD PMID:9463523 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression EXP Mercuric Chloride results in increased expression of HSP90B1 mRNA CTD PMID:17464326 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Mercuric Chloride results in increased expression of HSPA5 mRNA CTD PMID:17464326 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
increases phosphorylation		 EXP Mercuric Chloride results in increased expression of JUN mRNA; Mercuric Chloride results in increased expression of JUN protein
Mercuric Chloride results in increased phosphorylation of JUN protein		 CTD PMID:10696784 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation EXP Mercuric Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10696784 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases phosphorylation EXP Mercuric Chloride results in increased phosphorylation of MAPK9 protein CTD PMID:10696784 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5152
    role 5119
      biological role 5119
        aetiopathogenetic role 4721
          sensitiser 17
            mercury dichloride 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 5152
    subatomic particle 5143
      composite particle 5143
        hadron 5143
          baryon 5143
            nucleon 5143
              atomic nucleus 5143
                atom 5143
                  metal atom 243
                    transition element atom 199
                      d-block element atom 199
                        zinc group element atom 169
                          mercury atom 11
                            mercury molecular entity 11
                              mercury coordination entity 9
                                mercury dichloride 9
paths to the root