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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Medazepam
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Accession:CHEBI:31807 term browser browse the term
Synonyms:related_synonym: Formula=C16H15ClN2;   InChI=1S/C16H15ClN2/c1-19-10-9-18-16(12-5-3-2-4-6-12)14-11-13(17)7-8-15(14)19/h2-8,11H,9-10H2,1H3;   InChIKey=YLCXGBZIZBEVPZ-UHFFFAOYSA-N;   SMILES=C1(=CC2=C(C=C1)N(CCN=C2C=3C=CC=CC3)C)Cl;   medazepam HCl;   medazepam hydrochloride;   mezapam
 xref: CAS:2898-12-6;   Drug_Central:1654;   KEGG:D01292
 xref_mesh: MESH:D008472



show annotations for term's descendants           Sort by:
Medazepam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Medazepam results in decreased activity of AKR1C1 protein CTD PMID:11995921 PMID:12604236 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Medazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 PMID:12604236 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Medazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 PMID:12604236 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Medazepam results in increased expression of CYP3A4 mRNA CTD PMID:20080160 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO Medazepam binds to and results in increased activity of NR1I2 protein
Medazepam results in increased activity of NR1I2 protein
CTD PMID:20024649 PMID:20080160 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19915
    chemical entity 19913
      atom 19895
        nonmetal atom 19817
          carbon atom 19770
            organic molecular entity 19770
              Medazepam 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    p-block element atom 19834
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            Medazepam 5
paths to the root