bromobenzene - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	bromobenzene	go back to main search page
Accession:	CHEBI:3179	browse the term
Definition:	The simplest member of the class of bromobenzenes, that is benzene in which a single hydrogen has been substituted by a bromine. A liquid at room temperature (m.p. -30degreeC; b.p.760 156degreeC), it is used as a solvent, particularly for large-scale crystallisations, and for the introduction of phenyl groups in organic synthesis.
Synonyms:	related_synonym:	C6H5Br; Formula=C6H5Br; InChI=1S/C6H5Br/c7-6-4-2-1-3-5-6/h1-5H; InChIKey=QARVLSVVCXYDNA-UHFFFAOYSA-N; Monobromobenzene; PhBr; Phenyl bromide; SMILES=Brc1ccccc1
	xref:	Beilstein:1236661; CAS:108-86-1; KEGG:C11036
	xref_mesh:	MESH:C032036
	xref:	MetaCyc:BROMOBENZENE; PMID:10996478; PMID:24318069; Reaxys:1236661; Wikipedia:Bromobenzene

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Genes (794)

bromobenzene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetoacetyl-CoA synthetase

decreases expression

bromobenzene results in decreased expression of AACS mRNA

NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954

G

aminoadipate-semialdehyde synthase

increases expression

bromobenzene results in increased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

ATP binding cassette subfamily B member 1A

increases expression

bromobenzene results in increased expression of ABCB1A mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily B member 7

increases expression

bromobenzene results in increased expression of ABCB7 mRNA

NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858

G

ATP binding cassette subfamily C member 3

increases expression

bromobenzene results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

increases expression

bromobenzene results in increased expression of ABCC4 mRNA

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily C member 8

decreases expression

bromobenzene results in decreased expression of ABCC8 mRNA

NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510

G

ATP binding cassette subfamily G member 2

decreases expression

bromobenzene results in decreased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

abhydrolase domain containing 15

increases expression

bromobenzene results in increased expression of ABHD15 mRNA

NCBI chr10:62,363,209...62,368,600
Ensembl chr10:62,363,209...62,368,600

G

actin binding LIM protein family, member 3

increases expression

bromobenzene results in increased expression of ABLIM3 mRNA

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

acetyl-CoA acetyltransferase 2

decreases expression

bromobenzene results in decreased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

alkaline ceramidase 2

increases expression

bromobenzene results in increased expression of ACER2 mRNA

NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614

G

atypical chemokine receptor 2

increases expression

bromobenzene results in increased expression of ACKR2 mRNA

NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582

G

ATP citrate lyase

decreases expression

bromobenzene results in decreased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA thioesterase 4

increases expression

bromobenzene results in increased expression of ACOT4 mRNA

NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917

G

acyl-CoA synthetase bubblegum family member 1

increases expression

bromobenzene results in increased expression of ACSBG1 mRNA

NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391

G

acyl-CoA synthetase long-chain family member 1

decreases expression

bromobenzene results in decreased expression of ACSL1 mRNA

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase long-chain family member 3

decreases expression

bromobenzene results in decreased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

acyl-CoA synthetase short-chain family member 2

decreases expression

bromobenzene results in decreased expression of ACSS2 mRNA

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

actin, beta

increases expression

bromobenzene results in increased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin-like 7b

decreases expression

bromobenzene results in decreased expression of ACTL7B mRNA

NCBI chr 5:71,445,532...71,446,920
Ensembl chr 5:71,445,534...71,446,920

G

actinin alpha 4

decreases expression

bromobenzene results in decreased expression of ACTN4 mRNA

NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847

G

ADAM metallopeptidase with thrombospondin type 1 motif, 15

increases expression

bromobenzene results in increased expression of ADAMTS15 mRNA

NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249

G

ADAM metallopeptidase with thrombospondin type 1, motif 3

increases expression

bromobenzene results in increased expression of ADAMTS3 mRNA

NCBI chr14:18,231,128...18,437,771
Ensembl chr14:18,231,165...18,435,556

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

decreases expression

bromobenzene results in decreased expression of ADAMTS7 mRNA

NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328

G

adhesion G protein-coupled receptor F3

increases expression

bromobenzene results in increased expression of ADGRF3 mRNA

NCBI chr 6:26,133,176...26,144,601
Ensembl chr 6:26,133,192...26,144,601

G

adhesion G protein-coupled receptor G3

decreases expression

bromobenzene results in decreased expression of ADGRG3 mRNA

NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123

G

adhesion G protein-coupled receptor G5

increases expression

bromobenzene results in increased expression of ADGRG5 mRNA

NCBI chr19:10,074,787...10,098,640
Ensembl chr19:10,079,375...10,097,214

G

adrenomedullin 2

increases expression

bromobenzene results in increased expression of ADM2 mRNA

NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331

G

adenosine A2B receptor

decreases expression

bromobenzene results in decreased expression of ADORA2B mRNA

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

G

adrenoceptor alpha 2C

decreases expression

bromobenzene results in decreased expression of ADRA2C mRNA

NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846

G

aryl hydrocarbon receptor

increases expression

bromobenzene results in increased expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

absent in melanoma 2

decreases expression

bromobenzene results in decreased expression of AIM2 mRNA

NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975

G

aryl-hydrocarbon receptor-interacting protein

decreases expression

bromobenzene results in decreased expression of AIP mRNA

NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122

G

aldo-keto reductase family 7 member A3

increases expression

bromobenzene results in increased expression of AKR7A3 mRNA

PMID:12628495 PMID:15056800 PMID:32479839

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

aminolevulinate dehydratase

decreases activity
multiple interactions
decreases expression

bromobenzene results in decreased activity of ALAD protein
[Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein; Carbon Monoxide inhibits the reaction [[Phenobarbital co-treated with bromobenzene] results in decreased activity of ALAD protein]
bromobenzene results in decreased expression of ALAD mRNA

PMID:6740708 PMID:16140629 PMID:32479839

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

albumin

increases expression
affects binding

bromobenzene results in increased expression of ALB mRNA
bromobenzene metabolite binds to ALB protein

PMID:12018992 PMID:17305373 PMID:23288050

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A1

affects binding
increases expression

bromobenzene metabolite binds to ALDH1A1 protein
bromobenzene results in increased expression of ALDH1A1 mRNA

PMID:12628495 PMID:17305373

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

affects binding

bromobenzene metabolite binds to ALDH2 protein

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 9 family, member A1

affects binding

bromobenzene metabolite binds to ALDH9A1 protein

NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568

G

arachidonate 15-lipoxygenase

increases expression

bromobenzene results in increased expression of ALOX15 mRNA

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

G

ALS2 C-terminal like

increases expression

bromobenzene results in increased expression of ALS2CL mRNA

NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419

G

alpha-1-microglobulin/bikunin precursor

increases expression

bromobenzene results in increased expression of AMBP mRNA

NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331

G

angiopoietin-like 1

decreases expression

bromobenzene results in decreased expression of ANGPTL1 mRNA

NCBI chr13:68,963,186...68,981,649
Ensembl chr13:68,962,991...68,992,570

G

angiopoietin-like 4

increases expression

bromobenzene results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

angiopoietin-like 8

decreases expression

bromobenzene results in decreased expression of ANGPTL8 mRNA

NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490

G

ankyrin repeat and LEM domain containing 1

increases expression

bromobenzene results in increased expression of ANKLE1 mRNA

NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729

G

ankyrin repeat and MYND domain containing 1

increases expression

bromobenzene results in increased expression of ANKMY1 mRNA

NCBI chr 9:93,423,664...93,476,651
Ensembl chr 9:93,423,963...93,477,236

G

ankyrin repeat domain 1

decreases expression

bromobenzene results in decreased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

ankyrin repeat domain 13D

increases expression

bromobenzene results in increased expression of ANKRD13D mRNA

NCBI chr 1:201,565,712...201,577,987
Ensembl chr 1:201,565,712...201,577,933

G

ankyrin repeat domain 33B

increases expression

bromobenzene results in increased expression of ANKRD33B mRNA

NCBI chr 2:82,277,604...82,359,420
Ensembl chr 2:82,283,108...82,358,872

G

anillin, actin binding protein

increases expression

bromobenzene results in increased expression of ANLN mRNA

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

annexin A13

increases expression

bromobenzene results in increased expression of ANXA13 mRNA

NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907

G

APC regulator of WNT signaling pathway

increases expression

bromobenzene results in increased expression of APC mRNA

NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696

G

apolipoprotein C3

decreases expression

bromobenzene results in decreased expression of APOC3 mRNA

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein H

increases expression

bromobenzene results in increased expression of APOH mRNA

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

G

apolipoprotein L domain containing 1

increases expression

bromobenzene results in increased expression of APOLD1 mRNA

NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706

G

apolipoprotein M

increases expression

bromobenzene results in increased expression of APOM mRNA

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

aprataxin

decreases expression

bromobenzene results in decreased expression of APTX mRNA

NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855

G

arginase 1

affects binding
increases expression

bromobenzene metabolite binds to ARG1 protein
bromobenzene results in increased expression of ARG1 mRNA

PMID:17305373 PMID:32479839

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho GTPase activating protein 19

decreases expression

bromobenzene results in decreased expression of ARHGAP19 mRNA

NCBI chr 1:240,571,554...240,617,361
Ensembl chr 1:240,580,871...240,617,287

G

Rho GTPase activating protein 32

increases expression

bromobenzene results in increased expression of ARHGAP32 mRNA

NCBI chr 8:30,421,269...30,681,653
Ensembl chr 8:30,421,515...30,678,454

G

Rho guanine nucleotide exchange factor 19

decreases expression

bromobenzene results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203

G

AT-rich interaction domain 5A

increases expression

bromobenzene results in increased expression of ARID5A mRNA

NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597

G

armadillo repeat containing 7

increases expression

bromobenzene results in increased expression of ARMC7 mRNA

NCBI chr10:100,723,080...100,739,636
Ensembl chr10:100,723,105...100,739,636

G

arrestin domain containing 3

decreases expression

bromobenzene results in decreased expression of ARRDC3 mRNA

NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978

G

ankyrin repeat and SOCS box-containing 4

decreases expression

bromobenzene results in decreased expression of ASB4 mRNA

NCBI chr 4:33,506,992...33,544,630
Ensembl chr 4:33,506,992...33,544,630

G

anti-silencing function 1A histone chaperone

increases expression

bromobenzene results in increased expression of ASF1A mRNA

NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808

G

argininosuccinate lyase

increases expression

bromobenzene results in increased expression of ASL mRNA

NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

increases expression

bromobenzene results in increased expression of ATP12A mRNA

NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229

G

ATPase Na+/K+ transporting subunit beta 1

increases expression

bromobenzene results in increased expression of ATP1B1 mRNA

NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459

G

ATPase H+ transporting V0 subunit D2

increases expression

bromobenzene results in increased expression of ATP6V0D2 mRNA

NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354

G

ATPase H+ transporting V1 subunit C2

increases expression

bromobenzene results in increased expression of ATP6V1C2 mRNA

NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028

G

arginine vasopressin receptor 1A

affects expression

bromobenzene affects the expression of AVPR1A mRNA

NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215

G

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

increases expression

bromobenzene results in increased expression of B3GALNT1 mRNA

NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332

G

bile acid CoA:amino acid N-acyltransferase

decreases expression

bromobenzene results in decreased expression of BAAT mRNA

NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685

G

BTB domain and CNC homolog 1

increases expression

bromobenzene results in increased expression of BACH1 mRNA

NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447

G

Btg3 associated nuclear protein

decreases expression

bromobenzene results in decreased expression of BANP mRNA

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

brain expressed X-linked 1

increases expression

bromobenzene results in increased expression of BEX2 mRNA

NCBI chr X:99,219,014...99,220,518
Ensembl chr X:99,219,014...99,220,958

G

basic helix-loop-helix family, member a15

decreases expression

bromobenzene results in decreased expression of BHLHA15 mRNA

NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713

G

basic helix-loop-helix family, member e40

decreases expression

bromobenzene results in decreased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

betaine-homocysteine S-methyltransferase

decreases expression
increases expression

bromobenzene results in decreased expression of BHMT mRNA
bromobenzene results in increased expression of BHMT mRNA

PMID:12628495 PMID:15056800 PMID:32479839

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

basic helix-loop-helix ARNT like 1

increases expression

bromobenzene results in increased expression of BMAL1 mRNA

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

basic helix-loop-helix ARNT like 2

decreases expression

bromobenzene results in decreased expression of BMAL2 mRNA

NCBI chr 4:179,699,432...179,747,710
Ensembl chr 4:179,699,502...179,746,949

G

Bcl2 modifying factor

decreases expression

bromobenzene results in decreased expression of BMF mRNA

NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145

G

BMP/retinoic acid inducible neural specific 2

increases expression

bromobenzene results in increased expression of BRINP2 mRNA

NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810

G

BTB domain containing 19

increases expression

bromobenzene results in increased expression of BTBD19 mRNA

NCBI chr 5:130,596,966...130,605,403
Ensembl chr 5:130,597,684...130,604,335

G

similar to human chromosome 2 open reading frame 73

increases expression

bromobenzene results in increased expression of C14H2ORF73 mRNA

NCBI chr14:104,145,818...104,178,973
Ensembl chr14:104,145,818...104,178,973

G

C1q and TNF related 7

increases expression

bromobenzene results in increased expression of C1QTNF7 mRNA

NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410

G

complement C1r

decreases expression

bromobenzene results in decreased expression of C1R mRNA

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

G

similar to human chromosome 11 open reading frame 54

affects binding

bromobenzene metabolite binds to C8H11ORF54 protein

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 15 open reading frame 39

increases expression

bromobenzene results in increased expression of C8H15ORF39 mRNA

NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941

G

complement C9

decreases expression

bromobenzene results in decreased expression of C9 mRNA

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

G

calmodulin-like 3

increases expression

bromobenzene results in increased expression of CALML3 mRNA

NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175

G

calpain 1

decreases expression

bromobenzene results in decreased expression of CAPN1 mRNA

NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177

G

carbonic anhydrase 1

decreases expression

bromobenzene results in decreased expression of CAR1 mRNA

NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208

G

carbonic anhydrase 12

increases expression

bromobenzene results in increased expression of CA12 mRNA

NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440

G

carbonic anhydrase 2

increases expression

bromobenzene results in increased expression of CAR2 mRNA

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

G

carbonic anhydrase 3

affects binding
decreases expression

bromobenzene metabolite binds to CA3 protein
bromobenzene results in decreased expression of CA3 mRNA

PMID:17305373 PMID:32479839

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

caspase recruitment domain family, member 19

increases expression

bromobenzene results in increased expression of CARD19 mRNA

NCBI chr17:15,432,632...15,445,317
Ensembl chr17:15,432,612...15,445,318

G

Cbl proto-oncogene C

decreases expression

bromobenzene results in decreased expression of CBLC mRNA

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

G

coiled-coil domain containing 106

increases expression

bromobenzene results in increased expression of CCDC106 mRNA

NCBI chr 1:68,779,882...68,783,975
Ensembl chr 1:68,779,882...68,786,846

G

coiled-coil domain containing 122

increases expression

bromobenzene results in increased expression of CCDC122 mRNA

NCBI chr15:52,407,717...52,470,163
Ensembl chr15:52,407,717...52,470,163

G

coiled-coil domain containing 96

increases expression

bromobenzene results in increased expression of CCDC96 mRNA

NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888

G

C-C motif chemokine ligand 7

decreases expression

bromobenzene results in decreased expression of CCL7 mRNA

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

cellular communication network factor 2

increases expression

bromobenzene results in increased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin D1

decreases expression

bromobenzene results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin E1

decreases expression

bromobenzene results in decreased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

coiled-coil serine-rich protein 2

increases expression

bromobenzene results in increased expression of CCSER2 mRNA

NCBI chr16:12,613,103...12,725,764
Ensembl chr16:12,613,103...12,725,738

G

CD274 molecule

decreases expression

bromobenzene results in decreased expression of CD274 mRNA

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

CD3 epsilon subunit of T-cell receptor complex

increases expression

bromobenzene results in increased expression of CD3E mRNA

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

G

CD99 molecule-like 2

increases expression

bromobenzene results in increased expression of CD99L2 mRNA

G

cell division cycle 34, ubiqiutin conjugating enzyme

increases expression

bromobenzene results in increased expression of CDC34 mRNA

NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186

G

cadherin 10

increases expression

bromobenzene results in increased expression of CDH10 mRNA

NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995

G

cyclin-dependent kinase inhibitor 1A

increases expression

bromobenzene results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cysteine dioxygenase type 1

decreases expression
increases expression

bromobenzene results in decreased expression of CDO1 mRNA
bromobenzene results in increased expression of CDO1 mRNA

PMID:12628495 PMID:15056800

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

CDP-diacylglycerol synthase 2

increases expression

bromobenzene results in increased expression of CDS2 mRNA

NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541

G

chromatin licensing and DNA replication factor 1

decreases expression

bromobenzene results in decreased expression of CDT1 mRNA

NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659

G

CCAAT/enhancer binding protein delta

decreases expression

bromobenzene results in decreased expression of CEBPD mRNA

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

G

cell migration inducing hyaluronidase 1

increases expression

bromobenzene results in increased expression of CEMIP mRNA

NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415

G

centromere protein K

decreases expression

bromobenzene results in decreased expression of CENPK mRNA

NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706

G

centromere protein T

increases expression

bromobenzene results in increased expression of CENPT mRNA

NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142

G

centromere protein W

increases expression

bromobenzene results in increased expression of CENPW mRNA

NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464

G

cilia and flagella associated protein 95

decreases expression

bromobenzene results in decreased expression of CFAP95 mRNA

NCBI chr 1:221,123,786...221,242,963
Ensembl chr 1:221,131,813...221,242,963

G

cofilin 1

increases expression

bromobenzene results in increased expression of CFL1 mRNA

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression

bromobenzene results in increased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

charged multivesicular body protein 4C

increases expression

bromobenzene results in increased expression of CHMP4C mRNA

NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668

G

chordin-like 1

decreases expression

bromobenzene results in decreased expression of CHRDL1 mRNA

NCBI chr X:106,889,125...106,992,937
Ensembl chr X:106,889,125...106,992,921

G

cholinergic receptor nicotinic alpha 1 subunit

increases expression

bromobenzene results in increased expression of CHRNA1 mRNA

NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840

G

cholinergic receptor nicotinic alpha 5 subunit

increases expression

bromobenzene results in increased expression of CHRNA5 mRNA

NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146

G

circadian associated repressor of transcription

decreases expression

bromobenzene results in decreased expression of CIART mRNA

NCBI chr 2:183,419,819...183,424,845
Ensembl chr 2:183,419,819...183,423,313

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

affects expression

bromobenzene affects the expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

cardiotrophin-like cytokine factor 1

increases expression

bromobenzene results in increased expression of CLCF1 mRNA

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

G

claudin 1

increases expression

bromobenzene results in increased expression of CLDN1 mRNA

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 3

decreases expression

bromobenzene results in decreased expression of CLDN3 mRNA

NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001

G

C-type lectin domain family 2 member D-like 1

increases expression

bromobenzene results in increased expression of CLEC2DL1 mRNA

NCBI chr 4:162,263,635...162,274,882
Ensembl chr 4:162,263,639...162,274,880

G

clock circadian regulator

increases expression

bromobenzene results in increased expression of CLOCK mRNA

NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400

G

claspin

decreases expression

bromobenzene results in decreased expression of CLSPN mRNA

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

G

calsyntenin 3

decreases expression

bromobenzene results in decreased expression of CLSTN3 mRNA

NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769

G

clathrin, light chain B

increases expression

bromobenzene results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

contactin associated protein family member 4

decreases expression

bromobenzene results in decreased expression of CNTNAP4 mRNA

NCBI chr19:40,568,684...40,861,879
Ensembl chr19:40,568,684...40,854,656

G

collagen like tail subunit of asymmetric acetylcholinesterase

increases expression

bromobenzene results in increased expression of COLQ mRNA

NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107

G

coenzyme Q10B

affects expression

bromobenzene affects the expression of COQ10B mRNA

NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663

G

coronin 6

increases expression

bromobenzene results in increased expression of CORO6 mRNA

NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659

G

cytoplasmic polyadenylation element binding protein 2

increases expression

bromobenzene results in increased expression of CPEB2 mRNA

NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743

G

copine 1

increases expression

bromobenzene results in increased expression of CPNE1 mRNA

NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636

G

carnitine O-acetyltransferase

increases expression

bromobenzene results in increased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

cAMP responsive element binding protein 3-like 3

increases expression

bromobenzene results in increased expression of CREB3L3 mRNA

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

cellular repressor of E1A-stimulated genes 1

increases expression

bromobenzene results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

collapsin response mediator protein 1

affects expression

bromobenzene affects the expression of CRMP1 mRNA

NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177

G

cryptochrome circadian regulator 1

decreases expression

bromobenzene results in decreased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin, gamma A

decreases expression

bromobenzene results in decreased expression of CRYGA mRNA

NCBI chr 9:66,482,176...66,484,638
Ensembl chr 9:66,482,176...66,509,896

G

cysteine sulfinic acid decarboxylase

increases expression

bromobenzene results in increased expression of CSAD mRNA

NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615

G

CUB and Sushi multiple domains 1

increases expression

bromobenzene results in increased expression of CSMD1 mRNA

NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614

G

casein kinase 2 beta

increases expression

bromobenzene results in increased expression of CSNK2B mRNA

NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133

G

cathepsin L

increases expression

bromobenzene results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cut-like homeobox 2

increases expression

bromobenzene results in increased expression of CUX2 mRNA

NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806

G

C-X-C motif chemokine ligand 13

decreases expression

bromobenzene results in decreased expression of CXCL13 mRNA

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine receptor 6

decreases expression

bromobenzene results in decreased expression of CXCR6 mRNA

NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526

G

cytochrome b5 type A

increases expression

bromobenzene results in increased expression of CYB5A mRNA

NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome c, somatic

increases expression

bromobenzene results in increased expression of CYCS mRNA

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

bromobenzene results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 1, subfamily a, polypeptide 1

affects expression

bromobenzene affects the expression of CYP1A1 protein

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 26, subfamily a, polypeptide 1

increases expression

bromobenzene results in increased expression of CYP26A1 mRNA

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 26, subfamily b, polypeptide 1

decreases expression

bromobenzene results in decreased expression of CYP26B1 mRNA

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 27, subfamily b, polypeptide 1

increases expression

bromobenzene results in increased expression of CYP27B1 mRNA

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression

bromobenzene results in increased expression of CYP2B2 mRNA

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily c, polypeptide 12

increases expression

bromobenzene results in increased expression of CYP2C12 mRNA

NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression

bromobenzene results in increased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 9

decreases expression

bromobenzene results in decreased expression of CYP3A9 mRNA

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 4, subfamily a, polypeptide 3

increases expression

bromobenzene results in increased expression of CYP4A3 mRNA

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

G

cytochrome P450, family 51

decreases expression

bromobenzene results in decreased expression of CYP51 mRNA

PMID:12628495 PMID:32479839

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410

G

cytochrome P450 family 7 subfamily A member 1

increases expression

bromobenzene results in increased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 8 subfamily B member 1

affects expression

bromobenzene affects the expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

D-box binding PAR bZIP transcription factor

decreases expression

bromobenzene results in decreased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

DNA-damage inducible transcript 3

decreases expression

bromobenzene results in decreased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

D-dopachrome tautomerase

affects binding

bromobenzene metabolite binds to DDT protein

NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482

G

DEPP autophagy regulator 1

increases expression

bromobenzene results in increased expression of DEPP1 mRNA

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

derlin 3

decreases expression

bromobenzene results in decreased expression of DERL3 mRNA

NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027

G

7-dehydrocholesterol reductase

decreases expression

bromobenzene results in decreased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

DEAH-box helicase 40

increases expression

bromobenzene results in increased expression of DHX40 mRNA

NCBI chr10:71,584,546...71,621,479
Ensembl chr10:71,583,716...71,621,445

G

divergent protein kinase domain 1C

increases expression

bromobenzene results in increased expression of DIPK1C mRNA

NCBI chr18:78,087,972...78,109,910
Ensembl chr18:78,087,991...78,109,904

G

dispatched RND transporter family member 1

increases expression

bromobenzene results in increased expression of DISP1 mRNA

NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702

G

DLG associated protein 5

increases expression

bromobenzene results in increased expression of DLGAP5 mRNA

NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518

G

dematin actin binding protein

decreases expression

bromobenzene results in decreased expression of DMTN mRNA

NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601

G

dynein, axonemal, heavy chain 17

increases expression

bromobenzene results in increased expression of DNAH17 mRNA

NCBI chr10:103,244,144...103,364,953
Ensembl chr10:103,249,363...103,364,901

G

deoxyribonuclease 1 like 2

increases expression

bromobenzene results in increased expression of DNASE1L2 mRNA

NCBI chr10:13,471,850...13,473,447
Ensembl chr10:13,471,479...13,473,763

G

DNA methyltransferase 3 beta

increases expression

bromobenzene results in increased expression of DNMT3B mRNA

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

docking protein 7

increases expression

bromobenzene results in increased expression of DOK7 mRNA

NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386

G

dipeptidyl peptidase like 6

decreases expression

bromobenzene results in decreased expression of DPP6 mRNA

NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532

G

down-regulator of transcription 1

increases expression

bromobenzene results in increased expression of DR1 mRNA

NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638

G

desmocollin 2

increases expression

bromobenzene results in increased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

deltex E3 ubiquitin ligase 3

increases expression

bromobenzene results in increased expression of DTX3 mRNA

NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522

G

dual oxidase maturation factor 1

decreases expression

bromobenzene results in decreased expression of DUOXA1 mRNA

NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499

G

dihydrouridine synthase 4-like

increases expression

bromobenzene results in increased expression of DUS4L mRNA

NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449

G

dual specificity phosphatase 6

decreases expression

bromobenzene results in decreased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 8

increases expression

bromobenzene results in increased expression of DUSP8 mRNA

NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921

G

dynein light chain Tctex-type 4

increases expression

bromobenzene results in increased expression of DYNLT4 mRNA

NCBI chr 5:130,605,437...130,607,224
Ensembl chr 5:130,605,399...130,607,666

G

E2F transcription factor 7

increases expression

bromobenzene results in increased expression of E2F7 mRNA

NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734

G

enoyl-CoA delta isomerase 1

increases expression

bromobenzene results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

extracellular matrix protein 2

increases expression

bromobenzene results in increased expression of ECM2 mRNA

NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516

G

ectodysplasin-A receptor

decreases expression

bromobenzene results in decreased expression of EDAR mRNA

NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494

G

early endosome antigen 1

increases expression

bromobenzene results in increased expression of EEA1 mRNA

NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487

G

egl-9 family hypoxia-inducible factor 1

multiple interactions

[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HIF1A protein; [bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HMOX1 mRNA; [bromobenzene co-treated with EGLN1 mutant form] results in increased expression of PTGS2 mRNA

NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777

G

eukaryotic translation initiation factor 3, subunit C

increases expression

bromobenzene results in increased expression of EIF3C mRNA

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 5A

increases expression

bromobenzene results in increased expression of EIF5A mRNA

NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656

G

enolase 1

affects binding

bromobenzene metabolite binds to ENO1 protein

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

decreases expression

bromobenzene results in decreased expression of ENPP7 mRNA

NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589

G

epoxide hydrolase 1

increases expression

bromobenzene results in increased expression of EPHX1 mRNA

PMID:12628495 PMID:17538237 PMID:32479839

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

elongin BC and polycomb repressive complex 2 associated protein

increases expression

bromobenzene results in increased expression of EPOP mRNA

NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912

G

EPS8 like 3

increases expression

bromobenzene results in increased expression of EPS8L3 mRNA

NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085

G

glutamate-rich 5

decreases expression

bromobenzene results in decreased expression of ERICH5 mRNA

NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207

G

endoplasmic reticulum oxidoreductase 1 beta

increases expression

bromobenzene results in increased expression of ERO1B mRNA

NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398

G

endoplasmic reticulum protein 29

affects binding

bromobenzene metabolite binds to ERP29 protein

NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376

G

ethanolamine-phosphate phospho-lyase

increases expression

bromobenzene results in increased expression of ETNPPL mRNA

NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212

G

eva-1 homolog C

increases expression

bromobenzene results in increased expression of EVA1C mRNA

NCBI chr11:30,089,510...30,163,596
Ensembl chr11:30,089,365...30,163,596

G

coagulation factor XII

increases expression

bromobenzene results in increased expression of F12 mRNA

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

G

fatty acid binding protein 1

decreases expression
affects binding

bromobenzene results in decreased expression of FABP1 mRNA
bromobenzene metabolite binds to FABP1 protein

PMID:12628495 PMID:17305373

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 12

increases expression

bromobenzene results in increased expression of FABP12 mRNA

NCBI chr 2:91,539,568...91,554,999
Ensembl chr 2:91,500,539...91,554,996

G

fatty acid binding protein 7

affects binding

bromobenzene metabolite binds to FABP7 protein

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

fatty acid desaturase 1

decreases expression

bromobenzene results in decreased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid desaturase 2

decreases expression

bromobenzene results in decreased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

fumarylacetoacetate hydrolase

affects binding

bromobenzene metabolite binds to FAH protein

NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505

G

family with sequence similarity 180, member A

increases expression

bromobenzene results in increased expression of FAM180A mRNA

NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047

G

family with sequence similarity 222, member A

increases expression

bromobenzene results in increased expression of FAM222A mRNA

NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682

G

family with sequence similarity 83, member D

increases expression

bromobenzene results in increased expression of FAM83D mRNA

NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192

G

family with sequence similarity 83, member F

increases expression

bromobenzene results in increased expression of FAM83F mRNA

NCBI chr 7:112,211,164...112,240,454
Ensembl chr 7:112,211,164...112,240,452

G

family with sequence similarity 89, member A

decreases expression

bromobenzene results in decreased expression of FAM89A mRNA

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

fatty acid synthase

decreases expression

bromobenzene results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

fibrillin 2

increases expression

bromobenzene results in increased expression of FBN2 mRNA

NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976

G

F-box protein 30

increases expression

bromobenzene results in increased expression of FBXO30 mRNA

NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441

G

Fc alpha and mu receptor

increases expression

bromobenzene results in increased expression of FCAMR mRNA

NCBI chr13:42,273,891...42,288,002
Ensembl chr13:42,273,628...42,287,113

G

farnesyl diphosphate farnesyl transferase 1

decreases expression

bromobenzene results in decreased expression of FDFT1 mRNA

PMID:15056800 PMID:32479839

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

bromobenzene results in decreased expression of FDPS mRNA

PMID:15056800 PMID:32479839

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

flap structure-specific endonuclease 1

decreases expression

bromobenzene results in decreased expression of FEN1 mRNA

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

fibroblast growth factor 21

increases expression

bromobenzene results in increased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibrinogen gamma chain

decreases expression

bromobenzene results in decreased expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

fibrinogen-like 1

decreases expression

bromobenzene results in decreased expression of FGL1 mRNA

NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093

G

FGR proto-oncogene, Src family tyrosine kinase

decreases expression

bromobenzene results in decreased expression of FGR mRNA

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

G

fin bud initiation factor homolog

increases expression

bromobenzene results in increased expression of FIBIN mRNA

NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676

G

FKBP prolyl isomerase 5

increases expression

bromobenzene results in increased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

FLII, actin remodeling protein

increases expression

bromobenzene results in increased expression of FLII mRNA

PMID:12628495 PMID:16036859

NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970

G

filamin B

increases expression

bromobenzene results in increased expression of FLNB mRNA

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

G

FLVCR choline and putative heme transporter 2

increases expression

bromobenzene results in increased expression of FLVCR2 mRNA

NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353

G

formin-like 1

decreases expression

bromobenzene results in decreased expression of FMNL1 mRNA

NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357

G

flavin containing dimethylaniline monoxygenase 1

increases expression

bromobenzene results in increased expression of FMO1 mRNA

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

flavin containing dimethylaniline monoxygenase 2

increases expression

bromobenzene results in increased expression of FMO2 mRNA

NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308

G

flavin containing dimethylaniline monoxygenase 3

increases expression

bromobenzene results in increased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

fibronectin 1

decreases expression

bromobenzene results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

fibronectin type III domain containing 1

increases expression

bromobenzene results in increased expression of FNDC1 mRNA

NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259

G

FOS like 1, AP-1 transcription factor subunit

decreases expression

bromobenzene results in decreased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

follistatin like 3

increases expression

bromobenzene results in increased expression of FSTL3 mRNA

NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639

G

ferritin heavy chain 1

increases expression

bromobenzene results in increased expression of FTH1 mRNA

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

fucosyltransferase 1

increases expression

bromobenzene results in increased expression of FUT1 mRNA

NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616

G

frizzled class receptor 7

increases expression

bromobenzene results in increased expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

glucose-6-phosphate dehydrogenase

increases expression

bromobenzene results in increased expression of G6PDX mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

glutamate decarboxylase 2

increases expression

bromobenzene results in increased expression of GAD2 mRNA

NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155

G

growth arrest and DNA-damage-inducible, alpha

increases expression

bromobenzene results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, beta

increases expression

bromobenzene results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

growth arrest and DNA-damage-inducible, gamma

decreases expression

bromobenzene results in decreased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

galactose-3-O-sulfotransferase 1

increases expression

bromobenzene results in increased expression of GAL3ST1 mRNA

NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388

G

polypeptide N-acetylgalactosaminyltransferase 2

decreases expression

bromobenzene results in decreased expression of GALNT2 mRNA

NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813

G

guanidinoacetate N-methyltransferase

affects binding

bromobenzene metabolite binds to GAMT protein

NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778

G

gastrin

decreases expression

bromobenzene results in decreased expression of GAST mRNA

NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496

G

glucosylceramidase beta 3

increases expression

bromobenzene results in increased expression of GBA3 mRNA

NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653

G

guanylate binding protein 2

decreases expression

bromobenzene results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

guanylate binding protein 3

decreases expression

bromobenzene results in decreased expression of GBP3 mRNA

NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098

G

GC, vitamin D binding protein

increases expression

bromobenzene results in increased expression of GC mRNA

PMID:15056800 PMID:23288050

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

G

glutamate-cysteine ligase, catalytic subunit

increases expression

bromobenzene results in increased expression of GCLC protein

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

bromobenzene results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

growth differentiation factor 15

increases expression

bromobenzene results in increased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

GTP binding protein overexpressed in skeletal muscle

increases expression

bromobenzene results in increased expression of GEM mRNA

NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222

G

G elongation factor, mitochondrial 1

increases expression

bromobenzene results in increased expression of GFM1 mRNA

NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471

G

growth hormone releasing hormone receptor

decreases response to substance

GHRHR gene mutant form results in decreased susceptibility to bromobenzene

NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776

G

GIMAP family P-loop NTPase domain containing 1

decreases expression

bromobenzene results in decreased expression of GIMD1 mRNA

NCBI chr 2:221,103,878...221,138,559
Ensembl chr 2:221,103,878...221,138,553

G

gap junction protein, alpha 4

increases expression

bromobenzene results in increased expression of GJA4 mRNA

NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925

G

gap junction protein, beta 2

increases expression

bromobenzene results in increased expression of GJB2 mRNA

NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177

G

GLI family zinc finger 3

increases expression

bromobenzene results in increased expression of GLI3 mRNA

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

G

glutamate dehydrogenase 1

increases activity

bromobenzene results in increased activity of GLUD1 protein

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

G protein subunit alpha transducin 1

increases expression

bromobenzene results in increased expression of GNAT1 mRNA

NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671

G

glycine N-methyltransferase

affects binding

bromobenzene metabolite binds to GNMT protein

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

glutamic-oxaloacetic transaminase 1

increases expression

bromobenzene results in increased expression of GOT1 mRNA

PMID:15056800 PMID:32479839

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate acyltransferase 3

increases expression

bromobenzene results in increased expression of GPAT3 mRNA

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

G patch domain containing 4

increases expression

bromobenzene results in increased expression of GPATCH4 mRNA

NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684

G

GC-rich promoter binding protein 1-like 1

increases expression

bromobenzene results in increased expression of GPBP1L1 mRNA

NCBI chr 5:130,009,768...130,050,636
Ensembl chr 5:130,023,137...130,050,459

G

glycerol-3-phosphate dehydrogenase 1

affects binding

bromobenzene metabolite binds to GPD1 protein

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

G protein-coupled receptor 21

decreases expression

bromobenzene results in decreased expression of GPR21 mRNA

NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930

G

G protein-coupled receptor 39

increases expression

bromobenzene results in increased expression of GPR39 mRNA

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

G

G-protein coupled receptor 65

decreases expression

bromobenzene results in decreased expression of GPR65 mRNA

NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512

G

GPRIN family member 3

decreases expression

bromobenzene results in decreased expression of GPRIN3 mRNA

NCBI chr 4:88,572,062...88,657,369
Ensembl chr 4:88,563,607...88,657,429

G

glutamic--pyruvic transaminase

multiple interactions
increases activity

diisopropyl 1,3-dithiol-2-ylidenemalonate inhibits the reaction [bromobenzene results in increased activity of GPT protein]

PMID:3795300 PMID:32479839

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

decreases expression

bromobenzene results in decreased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

increases expression

bromobenzene results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione S-transferase alpha 2

increases expression

bromobenzene results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 5

increases expression

bromobenzene results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

increases expression
affects binding

bromobenzene results in increased expression of GSTM1 mRNA
bromobenzene metabolite binds to GSTM1 protein

PMID:12628495 PMID:17305373

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

affects binding

bromobenzene metabolite binds to GSTM2 protein

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 3

decreases expression

bromobenzene results in decreased expression of GSTP3 mRNA

PMID:15056800 PMID:32479839

NCBI chr 1:201,355,682...201,358,216
Ensembl chr 1:201,355,682...201,358,330

G

glutathione S-transferase theta 1

decreases expression

bromobenzene results in decreased expression of GSTT1 mRNA

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

guanylate cyclase 1 soluble subunit beta 2

decreases expression

bromobenzene results in decreased expression of GUCY1B2 mRNA

NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441

G

granzyme A

decreases expression

bromobenzene results in decreased expression of GZMA mRNA

NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493

G

hepcidin antimicrobial peptide

decreases expression

bromobenzene results in decreased expression of HAMP mRNA

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hydroxyacid oxidase 2

decreases expression

bromobenzene results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

hemoglobin alpha, adult chain 1

decreases expression

bromobenzene results in decreased expression of HBA-A1 mRNA

NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin subunit beta

affects binding

bromobenzene metabolite binds to HBB protein

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

heparin-binding EGF-like growth factor

increases expression

bromobenzene results in increased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

hemogen

increases expression

bromobenzene results in increased expression of HEMGN mRNA

NCBI chr 5:60,679,633...60,698,597
Ensembl chr 5:60,679,633...60,698,669

G

hes family bHLH transcription factor 6

decreases expression

bromobenzene results in decreased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

Hedgehog-interacting protein

decreases expression

bromobenzene results in decreased expression of HHIP mRNA

NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528

G

hypoxia inducible factor 1 subunit alpha

multiple interactions

[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HIF1A protein

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hypoxia inducible factor 3 subunit alpha

increases expression

bromobenzene results in increased expression of HIF3A mRNA

NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758

G

Holliday junction recognition protein

increases expression

bromobenzene results in increased expression of HJURP mRNA

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

hemojuvelin BMP co-receptor

increases expression

bromobenzene results in increased expression of HJV mRNA

NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850

G

hexokinase 3

decreases expression

bromobenzene results in decreased expression of HK3 mRNA

NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863

G

HLF transcription factor, PAR bZIP family member

decreases expression

bromobenzene results in decreased expression of HLF mRNA

NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

bromobenzene results in decreased expression of HMGCS1 mRNA

PMID:15056800 PMID:32479839

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

bromobenzene results in decreased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

high mobility group nucleosome binding domain 5

increases expression

bromobenzene results in increased expression of HMGN5 mRNA

NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441

G

heme oxygenase 1

increases expression
multiple interactions

bromobenzene results in increased expression of HMOX1 protein
bromobenzene results in increased expression of HMOX1 mRNA; bromobenzene results in increased expression of HMOX1 protein
[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HMOX1 mRNA

PMID:3343248 PMID:12628495 PMID:15056800 PMID:15976192 PMID:18078705 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, alpha

increases expression

bromobenzene results in increased expression of HNF4A mRNA

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

G

homer scaffold protein 2

increases expression

bromobenzene results in increased expression of HOMER2 mRNA

NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772

G

4-hydroxyphenylpyruvate dioxygenase-like

increases expression

bromobenzene results in increased expression of HPDL mRNA

NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233

G

hydroxysteroid 11-beta dehydrogenase 2

decreases expression

bromobenzene results in decreased expression of HSD11B2 mRNA

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 2

decreases expression

bromobenzene results in decreased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxysteroid (17-beta) dehydrogenase 7

decreases expression

bromobenzene results in decreased expression of HSD17B7 mRNA

NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017

G

heat shock protein family A (Hsp70) member 1A

increases expression

bromobenzene results in increased expression of HSPA1A mRNA; bromobenzene results in increased expression of HSPA1A protein

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

bromobenzene results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 4 like

decreases expression

bromobenzene results in decreased expression of HSPA4L mRNA

NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084

G

heat shock protein family A (Hsp70) member 5

decreases expression
increases expression
affects binding

bromobenzene results in decreased expression of HSPA5 mRNA
bromobenzene results in increased expression of HSPA5 mRNA
bromobenzene metabolite binds to HSPA5 protein

PMID:12018992 PMID:12628495 PMID:15056800

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 8

affects binding

bromobenzene metabolite binds to HSPA8 protein

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

HIV-1 Tat interactive protein 2

increases expression

bromobenzene results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

intercellular adhesion molecule 1

increases expression

bromobenzene analog results in increased expression of ICAM1 protein

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 2

increases expression

bromobenzene results in increased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

isocitrate dehydrogenase (NADP(+)) 1

affects binding

bromobenzene metabolite binds to IDH1 protein

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

bromobenzene results in decreased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 3

increases expression

bromobenzene results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon, alpha-inducible protein 27 like 2A

decreases expression

bromobenzene results in decreased expression of ISG12(B) mRNA

NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360

G

interferon-related developmental regulator 1

increases expression

bromobenzene results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

intraflagellar transport 122

increases expression

bromobenzene results in increased expression of IFT122 mRNA

NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458

G

immunoglobulin superfamily, DCC subclass, member 3

decreases expression

bromobenzene results in decreased expression of IGDCC3 mRNA

NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959

G

insulin-like growth factor 1

decreases expression

bromobenzene results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 2

increases expression

bromobenzene results in increased expression of IGFBP2 mRNA

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

immunoglobulin superfamily, member 7 like 1

decreases expression

bromobenzene results in decreased expression of IGSF7 L1 mRNA

NCBI chr10:100,174,955...100,182,713
Ensembl chr10:100,156,238...100,182,647

G

Indian hedgehog signaling molecule

decreases expression

bromobenzene results in decreased expression of IHH mRNA

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

G

IKAROS family zinc finger 4

increases expression

bromobenzene results in increased expression of IKZF4 mRNA

NCBI chr 7:1,063,283...1,102,940
Ensembl chr 7:1,056,890...1,084,341

G

interleukin 13 receptor subunit alpha 2

decreases expression

bromobenzene results in decreased expression of IL13RA2 mRNA

NCBI chr X:111,002,590...111,074,053
Ensembl chr X:111,002,592...111,072,381

G

interleukin 17 receptor B

increases expression

bromobenzene results in increased expression of IL17RB mRNA

NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125

G

interleukin 6 receptor

increases expression

bromobenzene results in increased expression of IL6R mRNA

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

G

inhibin subunit beta A

decreases expression

bromobenzene results in decreased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

inka box actin regulator 1

decreases expression

bromobenzene results in decreased expression of INKA1 mRNA

NCBI chr 8:108,674,263...108,675,953
Ensembl chr 8:108,674,263...108,675,953

G

inositol polyphosphate-4-phosphatase type II B

increases expression

bromobenzene results in increased expression of INPP4B mRNA

NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634

G

INSC, spindle orientation adaptor protein

increases expression

bromobenzene results in increased expression of INSC mRNA

NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:168,993,032...169,100,433

G

insulin induced gene 1

decreases expression

bromobenzene results in decreased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

insulin induced gene 2

increases expression

bromobenzene results in increased expression of INSIG2 mRNA

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

G

inositol hexakisphosphate kinase 2

affects expression

bromobenzene affects the expression of IP6K2 mRNA

NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166

G

IQ motif containing GTPase activating protein 3

increases expression

bromobenzene results in increased expression of IQGAP3 mRNA

NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956

G

interferon regulatory factor 2 binding protein 2

increases expression

bromobenzene results in increased expression of IRF2BP2 mRNA

NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642

G

insulin receptor substrate 2

increases expression

bromobenzene results in increased expression of IRS2 mRNA

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

iroquois homeobox 1

decreases expression

bromobenzene results in decreased expression of IRX1 mRNA

NCBI chr 1:31,294,615...31,300,444
Ensembl chr 1:31,294,615...31,300,444

G

inter-alpha-trypsin inhibitor heavy chain 4

decreases expression

bromobenzene results in decreased expression of ITIH4 mRNA

NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708

G

janus kinase and microtubule interacting protein 1

increases expression

bromobenzene results in increased expression of JAKMIP1 mRNA

NCBI chr14:73,646,299...73,766,830
Ensembl chr14:73,632,428...73,713,993

G

janus kinase and microtubule interacting protein 2

increases expression

bromobenzene results in increased expression of JAKMIP2 mRNA

NCBI chr18:35,532,552...35,747,938
Ensembl chr18:35,532,552...35,747,775

G

potassium voltage-gated channel modifier subfamily F member 1

increases expression

bromobenzene results in increased expression of KCNF1 mRNA

NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979

G

potassium inwardly-rectifying channel, subfamily J, member 15

decreases expression

bromobenzene results in decreased expression of KCNJ15 mRNA

NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952

G

potassium two pore domain channel subfamily K member 1

increases expression

bromobenzene results in increased expression of KCNK1 mRNA

NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724

G

potassium two pore domain channel subfamily K member 2

increases expression

bromobenzene results in increased expression of KCNK2 mRNA

NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435

G

potassium sodium-activated channel subfamily T member 1

increases expression

bromobenzene results in increased expression of KCNT1 mRNA

NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667

G

potassium channel tetramerization domain containing 15

increases expression

bromobenzene results in increased expression of KCTD15 mRNA

NCBI chr 1:87,258,658...87,271,979
Ensembl chr 1:87,258,658...87,273,497

G

kinesin family member 23

increases expression

bromobenzene results in increased expression of KIF23 mRNA

NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072

G

kinesin family member 6

increases expression

bromobenzene results in increased expression of KIF6 mRNA

NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006

G

killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

increases expression

bromobenzene results in increased expression of KIR3DL1 mRNA

NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050

G

kirre like nephrin family adhesion molecule 3

decreases expression

bromobenzene results in decreased expression of KIRREL3 mRNA

NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676

G

kinesin light chain 3

affects binding

bromobenzene metabolite binds to KLC3 protein

NCBI chr 1:79,045,842...79,055,809
Ensembl chr 1:79,045,844...79,055,416

G

KLF transcription factor 10

increases expression

bromobenzene results in increased expression of KLF10 mRNA

NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 12

decreases expression

bromobenzene results in decreased expression of KLF12 mRNA

NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056

G

KLF transcription factor 15

increases expression

bromobenzene results in increased expression of KLF15 mRNA

NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374

G

KLF transcription factor 9

increases expression

bromobenzene results in increased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

keratin 23

increases expression

bromobenzene results in increased expression of KRT23 mRNA

NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983

G

ladinin 1

increases expression

bromobenzene results in increased expression of LAD1 mRNA

NCBI chr13:47,249,605...47,263,967
Ensembl chr13:47,249,605...47,263,967

G

leucine aminopeptidase 3

decreases expression

bromobenzene results in decreased expression of LAP3 mRNA

NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359

G

lactate dehydrogenase B

decreases expression

bromobenzene results in decreased expression of LDHB mRNA

NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403

G

low density lipoprotein receptor

decreases expression

bromobenzene results in decreased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

leucine-rich repeat LGI family, member 2

increases expression

bromobenzene results in increased expression of LGI2 mRNA

NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407

G

leucine rich repeat containing G protein coupled receptor 5

decreases expression

bromobenzene results in decreased expression of LGR5 mRNA

NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446

G

lengsin, lens protein with glutamine synthetase domain

decreases expression

bromobenzene results in decreased expression of LGSN mRNA

NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907

G

lon peptidase 1, mitochondrial

increases expression

bromobenzene results in increased expression of LONP1 mRNA

NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771

G

LON peptidase N-terminal domain and ring finger 3

increases expression

bromobenzene results in increased expression of LONRF3 mRNA

NCBI chr X:115,565,214...115,603,886
Ensembl chr X:115,565,267...115,598,809

G

lysyl oxidase

increases expression

bromobenzene results in increased expression of LOX mRNA

NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477

G

lysophosphatidic acid receptor 3

increases expression

bromobenzene results in increased expression of LPAR3 mRNA

NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357

G

lipin 1

increases expression

bromobenzene results in increased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

leucine rich repeat containing 4

increases expression

bromobenzene results in increased expression of LRRC4 mRNA

NCBI chr 4:57,433,518...57,437,114
Ensembl chr 4:57,433,428...57,437,911

G

leucine rich repeat containing 58

increases expression

bromobenzene results in increased expression of LRRC58 mRNA

NCBI chr11:62,850,507...62,862,829
Ensembl chr11:62,847,562...62,862,829

G

leukocyte specific transcript 1

decreases expression

bromobenzene results in decreased expression of LST1 mRNA

NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997

G

latent transforming growth factor beta binding protein 2

decreases expression

bromobenzene results in decreased expression of LTBP2 mRNA

NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208

G

Ly6/Plaur domain containing 1

increases expression

bromobenzene results in increased expression of LYPD1 mRNA

NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493

G

Ly6/Plaur domain containing 3

affects expression

bromobenzene affects the expression of LYPD3 mRNA

NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901

G

mab-21 like 3

increases expression

bromobenzene results in increased expression of MAB21L3 mRNA

NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652

G

MAF bZIP transcription factor B

increases expression

bromobenzene results in increased expression of MAFB mRNA

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

MAF bZIP transcription factor F

increases expression

bromobenzene results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

membrane associated guanylate kinase, WW and PDZ domain containing 3

decreases expression

bromobenzene results in decreased expression of MAGI3 mRNA

NCBI chr 2:191,514,726...191,717,048
Ensembl chr 2:191,518,506...191,716,735

G

mal, T-cell differentiation protein

decreases expression

bromobenzene results in decreased expression of MAL mRNA

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mitogen-activated protein kinase kinase kinase 5

increases expression

bromobenzene results in increased expression of MAP3K5 mRNA

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen-activated protein kinase kinase kinase 6

increases expression

bromobenzene results in increased expression of MAP3K6 mRNA

NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212

G

mitogen-activated protein kinase kinase kinase 9

increases expression

bromobenzene results in increased expression of MAP3K9 mRNA

NCBI chr 6:101,423,754...101,488,822
Ensembl chr 6:101,430,292...101,488,822

G

mitogen activated protein kinase 14

increases phosphorylation

bromobenzene analog results in increased phosphorylation of MAPK14 protein

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

MAPK activated protein kinase 3

increases expression

bromobenzene results in increased expression of MAPKAPK3 mRNA

NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568

G

membrane associated ring-CH-type finger 1

increases expression

bromobenzene results in increased expression of MARCHF1 mRNA

NCBI chr16:23,255,551...24,114,290
Ensembl chr16:23,258,799...24,114,277

G

methionine adenosyltransferase 1A

increases expression

bromobenzene results in increased expression of MAT1A mRNA

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

G

myoglobin

decreases expression

bromobenzene results in decreased expression of MB mRNA

NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383

G

MCF.2 cell line derived transforming sequence

increases expression

bromobenzene results in increased expression of MCF2 mRNA

NCBI chr X:138,414,077...138,514,828
Ensembl chr X:138,409,256...138,514,446

G

minichromosome maintenance 10 replication initiation factor

increases expression

bromobenzene results in increased expression of MCM10 mRNA

NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364

G

minichromosome maintenance complex component 3

decreases expression

bromobenzene results in decreased expression of MCM3 mRNA

NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314

G

minichromosome maintenance complex component 6

decreases expression

bromobenzene results in decreased expression of MCM6 mRNA

NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960

G

mucolipin TRP cation channel 2

increases expression

bromobenzene results in increased expression of MCOLN2 mRNA

NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702

G

mitochondrial calcium uniporter dominant negative subunit beta

increases expression

bromobenzene results in increased expression of MCUB mRNA

NCBI chr 2:218,479,301...218,549,594
Ensembl chr 2:218,479,301...218,549,593

G

malate dehydrogenase 1B

decreases expression

bromobenzene results in decreased expression of MDH1B mRNA

NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933

G

meiosis specific with OB-fold

decreases expression

bromobenzene results in decreased expression of MEIOB mRNA

NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046

G

methionyl aminopeptidase 2

increases expression

bromobenzene results in increased expression of METAP2 mRNA

NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434

G

mex-3 RNA binding family member B

increases expression

bromobenzene results in increased expression of MEX3B mRNA

NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

bromobenzene results in increased expression of MFSD2A mRNA

NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

decreases expression

bromobenzene results in decreased expression of MGAT4B mRNA

NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229

G

MID1 interacting protein 1

decreases expression

bromobenzene results in decreased expression of MID1IP1 mRNA

NCBI chr X:12,060,993...12,063,318
Ensembl chr X:12,060,883...12,065,774

G

macrophage migration inhibitory factor

affects binding

bromobenzene metabolite binds to MIF protein

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

G

mirror-image polydactyly 1

increases expression

bromobenzene results in increased expression of MIPOL1 mRNA

NCBI chr 6:74,755,293...75,090,403
Ensembl chr 6:74,755,395...75,086,811

G

MAPK interacting serine/threonine kinase 2

decreases expression

bromobenzene results in decreased expression of MKNK2 mRNA

NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827

G

monocyte to macrophage differentiation-associated 2

decreases expression

bromobenzene results in decreased expression of MMD2 mRNA

NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773

G

molybdenum cofactor sulfurase

increases expression

bromobenzene results in increased expression of MOCOS mRNA

NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187

G

myosin phosphatase Rho interacting protein

increases expression

bromobenzene results in increased expression of MPRIP mRNA

NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118

G

mannose receptor, C type 1

increases expression

bromobenzene results in increased expression of MRC1 mRNA

NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857

G

maestro heat-like repeat family member 9

increases expression

bromobenzene results in increased expression of MROH9 mRNA

NCBI chr13:75,387,800...75,443,118
Ensembl chr13:75,387,746...75,443,092

G

membrane spanning 4-domains A1

decreases expression

bromobenzene results in decreased expression of MS4A1 mRNA

NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512

G

membrane-spanning 4-domains, subfamily A, member 6B-like 1

increases expression

bromobenzene results in increased expression of MS4A6BL1 mRNA

NCBI chr 1:208,243,561...208,255,400
Ensembl chr 1:208,243,559...208,257,340

G

Myb/SANT DNA binding domain containing 1

increases expression

bromobenzene results in increased expression of MSANTD1 mRNA

NCBI chr14:75,832,368...75,845,687
Ensembl chr14:75,835,380...75,844,183

G

methylsterol monooxygenase 1

decreases expression

bromobenzene results in decreased expression of MSMO1 mRNA

PMID:15056800 PMID:32479839

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

macrophage stimulating 1 receptor

decreases expression

bromobenzene results in decreased expression of MST1R mRNA

NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455

G

metallothionein 1

increases expression

bromobenzene results in increased expression of MT1 mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 2A

increases expression

bromobenzene results in increased expression of MT2A mRNA

PMID:15056800 PMID:32479839

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

metallothionein 4

increases expression

bromobenzene results in increased expression of MT4 mRNA

NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

increases expression

bromobenzene results in increased expression of MTHFD2 mRNA

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

methylenetetrahydrofolate reductase

decreases expression

bromobenzene results in decreased expression of MTHFR mRNA

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

MTSS I-BAR domain containing 1

increases expression

bromobenzene results in increased expression of MTSS1 mRNA

NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968

G

mucin 13, cell surface associated

decreases expression

bromobenzene results in decreased expression of MUC13 mRNA

NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727

G

murinoglobulin 1

decreases expression

bromobenzene results in decreased expression of MUG1 mRNA

NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051

G

murinoglobulin 2

decreases expression

bromobenzene results in decreased expression of PZP mRNA

NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475

G

mevalonate diphosphate decarboxylase

decreases expression

bromobenzene results in decreased expression of MVD mRNA

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

mevalonate kinase

decreases expression

bromobenzene results in decreased expression of MVK mRNA

NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882

G

MX dynamin like GTPase 1

decreases expression

bromobenzene results in decreased expression of MX1 mRNA

NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507

G

MYB proto-oncogene like 1

increases expression

bromobenzene results in increased expression of MYBL1 mRNA

NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183

G

MYC proto-oncogene, bHLH transcription factor

increases expression

bromobenzene results in increased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myosin heavy chain 7B

increases expression

bromobenzene results in increased expression of MYH7B mRNA

NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084

G

myosin light chain kinase 3

decreases expression

bromobenzene results in decreased expression of MYLK3 mRNA

NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954

G

myosin IXb

decreases expression

bromobenzene results in decreased expression of MYO9B mRNA

PMID:15056800 PMID:32479839

NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126

G

myomesin 2

increases expression

bromobenzene results in increased expression of MYOM2 mRNA

NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772

G

nicotinamide phosphoribosyltransferase

increases expression

bromobenzene results in increased expression of NAMPT mRNA

NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100

G

N-acetyltransferase 8 (GCN5-related) family member 5

decreases expression

bromobenzene results in decreased expression of NAT8F5 mRNA

NCBI chr 4:118,260,323...118,285,038
Ensembl chr 4:118,260,252...118,285,704

G

neurocalcin delta

increases expression

bromobenzene results in increased expression of NCALD mRNA

NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496

G

neutral cholesterol ester hydrolase 1

increases expression

bromobenzene results in increased expression of NCEH1 mRNA

NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588

G

N-deacetylase and N-sulfotransferase 1

decreases expression

bromobenzene results in decreased expression of NDST1 mRNA

NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191

G

nei-like DNA glycosylase 2

increases expression

bromobenzene results in increased expression of NEIL2 mRNA

NCBI chr15:37,444,676...37,454,863
Ensembl chr15:37,445,381...37,454,863

G

nestin

increases expression

bromobenzene results in increased expression of NES mRNA

NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777

G

nuclear factor, erythroid 2

decreases expression

bromobenzene results in decreased expression of NFE2 mRNA

NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108

G

NFE2 like bZIP transcription factor 2

increases localization
increases expression

bromobenzene results in increased localization of NFE2L2 protein
bromobenzene analog results in increased expression of NFE2L2 protein

PMID:18078705 PMID:19427879

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NHERF family PDZ scaffold protein 1

decreases expression

bromobenzene results in decreased expression of NHERF1 mRNA

NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598

G

NIM1 serine/threonine protein kinase

increases expression

bromobenzene results in increased expression of NIM1K mRNA

NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762

G

NK1 homeobox 2

increases expression

bromobenzene results in increased expression of NKX1-2 mRNA

NCBI chr 1:187,386,370...187,391,252
Ensembl chr 1:187,388,711...187,391,149

G

nicotinamide riboside kinase 2

increases expression

bromobenzene results in increased expression of NMRK2 mRNA

NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922

G

nocturnin

increases expression

bromobenzene results in increased expression of NOCT mRNA

NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400

G

nucleolar protein 8

increases expression

bromobenzene results in increased expression of NOL8 mRNA

NCBI chr17:14,990,394...15,013,784
Ensembl chr17:14,990,417...15,013,848

G

NADPH oxidase 4

decreases expression

bromobenzene results in decreased expression of NOX4 mRNA

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

G

neuronal PAS domain protein 2

increases expression

bromobenzene results in increased expression of NPAS2 mRNA

NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320

G

nucleophosmin 1

increases expression

bromobenzene results in increased expression of NPM1 mRNA

NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645

G

natriuretic peptide receptor 3

decreases expression

bromobenzene results in decreased expression of NPR3 mRNA

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

G

neuropeptide S receptor 1

decreases expression

bromobenzene results in decreased expression of NPSR1 mRNA

NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558

G

NAD(P)H quinone dehydrogenase 1

affects response to substance
increases expression

NQO1 protein affects the susceptibility to bromobenzene
bromobenzene results in increased expression of NQO1 mRNA

PMID:10092053 PMID:15976192 PMID:17538237 PMID:32479839

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor binding factor 2

increases expression

bromobenzene results in increased expression of NRBF2 mRNA

NCBI chr20:21,308,555...21,326,881
Ensembl chr20:21,308,576...21,326,818

G

neuronal regeneration related protein

decreases expression

bromobenzene results in decreased expression of NREP mRNA

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

neurotrophic receptor tyrosine kinase 1

increases expression

bromobenzene results in increased expression of NTRK1 mRNA

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

nudix hydrolase 4

increases expression

bromobenzene results in increased expression of NUDT4 mRNA

NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615

G

nuclear protein 1, transcriptional regulator

decreases expression

bromobenzene results in decreased expression of NUPR1 mRNA

NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281

G

neurexophilin 3

decreases expression

bromobenzene results in decreased expression of NXPH3 mRNA

NCBI chr10:80,456,283...80,459,949
Ensembl chr10:80,455,429...80,462,415

G

outer dense fiber of sperm tails 2-like

increases expression

bromobenzene results in increased expression of ODF2L mRNA

NCBI chr 2:234,036,049...234,072,751
Ensembl chr 2:234,033,652...234,072,747

G

olfactory receptor 35

increases expression

bromobenzene results in increased expression of OLR35 mRNA

NCBI chr 1:153,994,678...154,043,281
Ensembl chr 1:154,041,306...154,043,257

G

osteomodulin

increases expression

bromobenzene results in increased expression of OMD mRNA

NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441

G

origin recognition complex, subunit 1

increases expression

bromobenzene results in increased expression of ORC1 mRNA

NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375

G

orosomucoid 1

increases expression

bromobenzene results in increased expression of ORM1 mRNA

NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154

G

oxysterol binding protein 2

increases expression

bromobenzene results in increased expression of OSBP2 mRNA

NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786

G

oxysterol binding protein-like 8

decreases expression

bromobenzene results in decreased expression of OSBPL8 mRNA

NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888

G

oxidative stress induced growth inhibitor 1

increases expression

bromobenzene results in increased expression of OSGIN1 mRNA

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

OTU deubiquitinase 6B

increases expression

bromobenzene results in increased expression of OTUD6B mRNA

NCBI chr 5:28,181,992...28,214,486
Ensembl chr 5:28,023,594...28,214,334

G

3-oxoacid CoA transferase 1

decreases expression

bromobenzene results in decreased expression of OXCT1 mRNA

NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714

G

purinergic receptor P2Y12

increases expression

bromobenzene results in increased expression of P2RY12 mRNA

NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361

G

prolyl 4-hydroxylase subunit beta

affects binding

bromobenzene metabolite binds to P4HB protein

NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500

G

peptidyl arginine deiminase 1

increases expression

bromobenzene results in increased expression of PADI1 mRNA

NCBI chr 5:153,119,566...153,152,034
Ensembl chr 5:153,119,566...153,152,034

G

Parkinsonism associated deglycase

affects binding

bromobenzene metabolite binds to PARK7 protein

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

G

poly (ADP-ribose) polymerase family, member 14

decreases expression

bromobenzene results in decreased expression of PARP14 mRNA

NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916

G

paired box 3

decreases expression

bromobenzene results in decreased expression of PAX3 mRNA

NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042

G

paired box 8

increases expression

bromobenzene results in increased expression of PAX8 mRNA

NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363

G

protocadherin 8

increases expression

bromobenzene results in increased expression of PCDH8 mRNA

NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872

G

protocadherin beta 3

decreases expression

bromobenzene results in decreased expression of PCDHB3 mRNA

NCBI chr18:29,011,667...29,014,221
Ensembl chr18:29,011,816...29,015,188

G

Purkinje cell protein 4

increases expression

bromobenzene results in increased expression of PCP4 mRNA

NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725

G

proprotein convertase subtilisin/kexin type 1

increases expression

bromobenzene results in increased expression of PCSK1 mRNA

NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434

G

proprotein convertase subtilisin/kexin type 9

decreases expression

bromobenzene results in decreased expression of PCSK9 mRNA

NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688

G

phosphate cytidylyltransferase 1A, choline

increases expression

bromobenzene results in increased expression of PCYT1A mRNA

NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357

G

phosphodiesterase 6C

decreases expression

bromobenzene results in decreased expression of PDE6C mRNA

NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315

G

platelet derived growth factor receptor beta

increases expression

bromobenzene results in increased expression of PDGFRB mRNA

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

protein disulfide isomerase family A, member 3

affects binding

bromobenzene metabolite binds to PDIA3 protein

NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236

G

protein disulfide isomerase family A, member 5

decreases expression

bromobenzene results in decreased expression of PDIA5 mRNA

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

protein disulfide isomerase family A, member 6

affects binding

bromobenzene metabolite binds to PDIA6 protein

NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613

G

pyruvate dehydrogenase kinase 4

increases expression

bromobenzene results in increased expression of PDK4 mRNA

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

phosphatidylethanolamine binding protein 1

affects binding

bromobenzene metabolite binds to PEBP1 protein

NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862

G

period circadian regulator 1

increases expression

bromobenzene results in increased expression of PER1 mRNA

NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431

G

period circadian regulator 2

decreases expression

bromobenzene results in decreased expression of PER2 mRNA

NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459

G

peroxisomal biogenesis factor 11 alpha

increases expression

bromobenzene results in increased expression of PEX11A mRNA

NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

increases expression

bromobenzene results in increased expression of PFKFB1 mRNA

NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182

G

phosphoglycerate kinase 1

affects binding

bromobenzene metabolite binds to PGK1 protein

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

pleckstrin homology-like domain, family A, member 1

increases expression

bromobenzene results in increased expression of PHLDA1 mRNA

NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861

G

phosphatidylinositol glycan anchor biosynthesis, class U

increases expression

bromobenzene results in increased expression of PIGU mRNA

NCBI chr 3:143,784,831...143,881,268
Ensembl chr 3:143,784,832...143,880,807

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

bromobenzene results in decreased expression of PIK3R1 mRNA

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

Pim-3 proto-oncogene, serine/threonine kinase

increases expression

bromobenzene results in increased expression of PIM3 mRNA

NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587

G

phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2

increases expression

bromobenzene results in increased expression of PIP4P2 mRNA

NCBI chr 5:28,259,821...28,307,225
Ensembl chr 5:28,259,760...28,307,225

G

pirin

increases expression

bromobenzene results in increased expression of PIR mRNA

NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218

G

pyruvate kinase L/R

decreases expression

bromobenzene results in decreased expression of PKLR mRNA

NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870

G

pleckstrin homology domain containing M3

increases expression

bromobenzene results in increased expression of PLEKHM3 mRNA

NCBI chr 9:66,166,233...66,325,332
Ensembl chr 9:66,166,321...66,325,294

G

perilipin 2

increases expression

bromobenzene results in increased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

perilipin 5

increases expression

bromobenzene results in increased expression of PLIN5 mRNA

NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120

G

polo-like kinase 3

increases expression

bromobenzene results in increased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

phospholipid phosphatase related 1

increases expression

bromobenzene results in increased expression of PLPPR1 mRNA

NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835

G

phospholipid phosphatase related 3

decreases expression

bromobenzene results in decreased expression of PLPPR3 mRNA

NCBI chr 7:9,831,162...9,842,434
Ensembl chr 7:9,831,162...9,845,296

G

plastin 1

decreases expression

bromobenzene results in decreased expression of PLS1 mRNA

NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195

G

plexin A2

decreases expression

bromobenzene results in decreased expression of PLXNA2 mRNA

NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979

G

patatin-like phospholipase domain containing 3

decreases expression

bromobenzene results in decreased expression of PNPLA3 mRNA

NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077

G

DNA polymerase gamma 2, accessory subunit

increases expression

bromobenzene results in increased expression of POLG2 mRNA

NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008

G

DNA polymerase theta

increases expression

bromobenzene results in increased expression of POLQ mRNA

NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878

G

cytochrome p450 oxidoreductase

increases expression

bromobenzene results in increased expression of POR mRNA

PMID:12628495 PMID:32479839

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

PPARG coactivator 1 alpha

increases expression

bromobenzene results in increased expression of PPARGC1A mRNA

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

phosphoribosyl pyrophosphate amidotransferase

increases expression

bromobenzene results in increased expression of PPAT mRNA

NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144

G

phosphopantothenoylcysteine synthetase

increases expression

bromobenzene results in increased expression of PPCS mRNA

NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933

G

protein phosphatase, Mg2+/Mn2+ dependent, 1K

increases expression

bromobenzene results in increased expression of PPM1K mRNA

NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:87,612,204...87,636,152

G

protein phosphatase 1, regulatory subunit 3G

increases expression

bromobenzene results in increased expression of PPP1R3G mRNA

NCBI chr17:28,874,956...28,878,288
Ensembl chr17:28,876,482...28,877,525

G

protein phosphatase 2 scaffold subunit A beta

increases expression

bromobenzene results in increased expression of PPP2R1B mRNA

NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485

G

protein phosphatase targeting COQ7

increases expression

bromobenzene results in increased expression of PPTC7 mRNA

NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339

G

peroxiredoxin 6

affects binding

bromobenzene metabolite binds to PRDX6 protein

NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355

G

prickle planar cell polarity protein 1

increases expression

bromobenzene results in increased expression of PRICKLE1 mRNA

NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113

G

proline rich membrane anchor 1

decreases expression

bromobenzene results in decreased expression of PRIMA1 mRNA

NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921

G

protein kinase AMP-activated non-catalytic subunit gamma 3

increases expression

bromobenzene results in increased expression of PRKAG3 mRNA

NCBI chr 9:76,295,715...76,304,959
Ensembl chr 9:76,295,715...76,304,959

G

protein arginine methyltransferase 7

increases expression

bromobenzene results in increased expression of PRMT7 mRNA

NCBI chr19:34,110,724...34,161,531
Ensembl chr19:34,110,747...34,162,577

G

prokineticin 1

decreases expression

bromobenzene results in decreased expression of PROK1 mRNA

NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250

G

pre-mRNA processing factor 3

decreases expression

bromobenzene results in decreased expression of PRPF3 mRNA

NCBI chr 2:183,379,041...183,403,526
Ensembl chr 2:183,378,718...183,403,489

G

proline rich 30

increases expression

bromobenzene results in increased expression of PRR30 mRNA

NCBI chr 6:25,415,069...25,417,582
Ensembl chr 6:25,414,868...25,417,585

G

proline rich and Gla domain 4

decreases expression

bromobenzene results in decreased expression of PRRG4 mRNA

NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273

G

phosphoribosyl transferase domain containing 1

decreases expression

bromobenzene results in decreased expression of PRTFDC1 mRNA

NCBI chr17:83,549,608...83,654,517
Ensembl chr17:83,548,803...83,655,179

G

proteasome 20S subunit alpha 1

increases expression

bromobenzene results in increased expression of PSMA1 mRNA

NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472

G

proteasome 20S subunit alpha 3

increases expression

bromobenzene results in increased expression of PSMA3 mRNA

NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965

G

proteasome 20S subunit beta 3

increases expression

bromobenzene results in increased expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 20S subunit beta 5

increases expression

bromobenzene results in increased expression of PSMB5 mRNA

NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440

G

proteasome 26S subunit, ATPase 3

affects binding

bromobenzene metabolite binds to PSMC3 protein

NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358

G

proteasome 26S subunit, ATPase 4

affects binding

bromobenzene metabolite binds to PSMC4 protein

NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494

G

proteasome 26S subunit, ATPase 5

increases expression

bromobenzene results in increased expression of PSMC5 mRNA

NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135

G

proteasome 26S subunit, non-ATPase 5

increases expression

bromobenzene results in increased expression of PSMD5 mRNA

NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029

G

proteasome activator subunit 1

affects binding

bromobenzene metabolite binds to PSME1 protein

NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890

G

prostaglandin D2 synthase

increases expression

bromobenzene results in increased expression of PTGDS mRNA

NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

prothymosin alpha

increases expression

bromobenzene results in increased expression of PTMA mRNA

NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333

G

protein tyrosine phosphatase, non-receptor type 14

increases expression

bromobenzene results in increased expression of PTPN14 mRNA

NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088

G

protein tyrosine phosphatase, receptor type, C-associated protein

decreases expression

bromobenzene results in decreased expression of PTPRCAP mRNA

NCBI chr 1:201,449,133...201,451,293
Ensembl chr 1:201,449,113...201,451,288

G

protein tyrosine phosphatase, receptor type, G

increases expression

bromobenzene results in increased expression of PTPRG mRNA

NCBI chr15:12,871,706...13,552,186
Ensembl chr15:12,871,721...13,554,094

G

protein tyrosine phosphatase, receptor type, U

increases expression

bromobenzene results in increased expression of PTPRU mRNA

NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768

G

PVR cell adhesion molecule

increases expression

bromobenzene results in increased expression of PVR mRNA

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

G

glycogen phosphorylase, muscle associated

decreases expression

bromobenzene results in decreased expression of PYGM mRNA

NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368

G

pyroglutamylated RFamide peptide receptor

increases expression

bromobenzene results in increased expression of QRFPR mRNA

NCBI chr 2:119,053,083...119,096,864
Ensembl chr 2:119,053,511...119,096,792

G

RAB23, member RAS oncogene family

increases expression

bromobenzene results in increased expression of RAB23 mRNA

NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927

G

RAB30, member RAS oncogene family

increases expression

bromobenzene results in increased expression of RAB30 mRNA

NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181

G

RAB9B, member RAS oncogene family

decreases expression

bromobenzene results in decreased expression of RAB9B mRNA

NCBI chr X:100,220,897...100,231,591
Ensembl chr X:100,220,894...100,231,701

G

RAD51 recombinase

decreases expression

bromobenzene results in decreased expression of RAD51 mRNA

NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035

G

RAD54 like 2

decreases expression

bromobenzene results in decreased expression of RAD54L2 mRNA

NCBI chr 8:107,324,945...107,427,033
Ensembl chr 8:107,327,420...107,427,106

G

RAN, member RAS oncogene family

increases expression

bromobenzene results in increased expression of RAN mRNA

NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276

G

ras related dexamethasone induced 1

increases expression

bromobenzene results in increased expression of RASD1 mRNA

NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186

G

RAS-like, family 10, member A

decreases expression

bromobenzene results in decreased expression of RASL10A mRNA

NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468

G

REC8 meiotic recombination protein

increases expression

bromobenzene results in increased expression of REC8 mRNA

NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326

G

regenerating family member 4

decreases expression

bromobenzene results in decreased expression of REG4 mRNA

NCBI chr 2:185,818,946...185,833,252
Ensembl chr 2:185,821,210...185,833,353

G

RGD1562699

decreases expression

bromobenzene results in decreased expression of RGD1562699 mRNA

NCBI chr18:57,826,815...57,831,464
Ensembl chr18:57,827,117...57,827,989

G

repulsive guidance molecule BMP co-receptor a

increases expression

bromobenzene results in increased expression of RGMA mRNA

NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918

G

regucalcin

affects binding

bromobenzene metabolite binds to RGN protein

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

G

regulator of G-protein signaling 1

increases expression

bromobenzene results in increased expression of RGS1 mRNA

NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984

G

regulator of G-protein signaling 20

increases expression

bromobenzene results in increased expression of RGS20 mRNA

NCBI chr 5:14,484,436...14,614,317
Ensembl chr 5:14,534,775...14,614,084

G

regulator of G-protein signaling 3

decreases expression

bromobenzene results in decreased expression of RGS3 mRNA

NCBI chr 5:76,022,038...76,161,895
Ensembl chr 5:76,022,001...76,161,894

G

regulator of G protein signaling 9 binding protein

decreases expression

bromobenzene results in decreased expression of RGS9BP mRNA

NCBI chr 1:88,249,438...88,250,151
Ensembl chr 1:88,249,438...88,250,151

G

rhomboid domain containing 2

increases expression

bromobenzene results in increased expression of RHBDD2 mRNA

NCBI chr12:21,043,605...21,054,305
Ensembl chr12:21,043,608...21,054,289

G

reactive intermediate imine deaminase A homolog

affects binding

bromobenzene metabolite binds to RIDA protein

NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716

G

ring finger protein, LIM domain interacting

increases expression

bromobenzene results in increased expression of RLIM mRNA

NCBI chr X:68,983,259...69,004,368
Ensembl chr X:68,988,375...69,004,271

G

ribonuclease A family member 11

affects expression

bromobenzene affects the expression of RNASE11 mRNA

NCBI chr15:24,268,206...24,270,192
Ensembl chr15:24,268,207...24,270,192

G

ring finger protein 151

increases expression

bromobenzene results in increased expression of RNF151 mRNA

NCBI chr10:13,742,682...13,747,192
Ensembl chr10:13,742,682...13,745,000

G

rhophilin associated tail protein 1

increases expression

bromobenzene results in increased expression of ROPN1 mRNA

NCBI chr11:66,097,854...66,127,148
Ensembl chr11:66,097,856...66,127,148

G

ribosomal protein L15

increases expression

bromobenzene results in increased expression of RPL15 mRNA

NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165

G

ribosomal protein L22

increases expression

bromobenzene results in increased expression of RPL22 mRNA

NCBI chr 5:162,835,241...162,843,394
Ensembl chr 5:162,833,740...162,843,368
Ensembl chr 7:162,833,740...162,843,368
Ensembl chr 4:162,833,740...162,843,368

G

ribosomal protein L27A

increases expression

bromobenzene results in increased expression of RPL27A mRNA

NCBI chr 1:163,539,732...163,542,771

G

ribosomal protein L35

increases expression
decreases expression

bromobenzene results in increased expression of RPL35 mRNA
bromobenzene results in decreased expression of RPL35 mRNA

PMID:12628495 PMID:15056800

NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243

G

ribosomal protein L6

increases expression

bromobenzene results in increased expression of RPL6 mRNA

NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921

G

reprimo, TP53 dependent G2 arrest mediator homolog

increases expression

bromobenzene results in increased expression of RPRM mRNA

NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998

G

ribosomal protein S11

increases expression

bromobenzene results in increased expression of RPS11 mRNA

NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874

G

ribosomal protein S2

increases expression

bromobenzene results in increased expression of RPS2 mRNA

NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163

G

ribosomal protein S26

increases expression

bromobenzene results in increased expression of RPS26 mRNA

NCBI chr 7:1,057,332...1,058,882

G

ribosomal protein S26 like 1

increases expression

bromobenzene results in increased expression of RPS26L1 mRNA

NCBI chr 7:62,981,687...62,982,757
Ensembl chr 7:62,981,946...62,982,326

G

ribosomal protein S3a

increases expression

bromobenzene results in increased expression of RPS3A mRNA

NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055

G

ribosomal protein S6 kinase B1

increases expression

bromobenzene results in increased expression of RPS6KB1 mRNA

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

G

ribosomal protein S8

increases expression

bromobenzene results in increased expression of RPS8 mRNA

NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268

G

ribosomal RNA processing 9, U3 small nucleolar RNA binding protein

decreases expression

bromobenzene results in decreased expression of RRP9 mRNA

NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123

G

arginine and serine rich protein 1

decreases expression

bromobenzene results in decreased expression of RSRP1 mRNA

NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523

G

RT1 class I, locus CE10

increases expression

bromobenzene results in increased expression of RT1-CE10 mRNA

NCBI chr20:3,377,284...3,380,301

G

RT1 class I, locus CE3

increases expression

bromobenzene results in increased expression of RT1-CE3 mRNA

NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081

G

RT1 class Ib, locus M2

increases expression

bromobenzene results in increased expression of RT1-M2 mRNA

NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723

G

RT1 class I, locus M6, gene 2

increases expression

bromobenzene results in increased expression of RT1-M6-2 mRNA

NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215

G

RT1 class Ib, locus N1

increases expression
decreases expression

bromobenzene results in increased expression of RT1-N1 mRNA
bromobenzene results in decreased expression of RT1-N1 mRNA

PMID:12628495 PMID:15056800

G

RT1 class Ib, locus S2

increases expression

bromobenzene results in increased expression of RT1-S2 mRNA

NCBI chr20:2,650,233...2,651,654
Ensembl chr20:2,649,964...2,652,027

G

reticulon 4 receptor-like 2

decreases expression

bromobenzene results in decreased expression of RTN4RL2 mRNA

NCBI chr 3:69,954,557...69,971,108
Ensembl chr 3:69,955,169...69,971,488

G

sacsin molecular chaperone

increases expression

bromobenzene results in increased expression of SACS mRNA

NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335

G

sterile alpha motif domain containing 4A

increases expression

bromobenzene results in increased expression of SAMD4A mRNA

NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380

G

suppressor APC domain containing 2

increases expression

bromobenzene results in increased expression of SAPCD2 mRNA

NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546

G

SAM and SH3 domain containing 1

increases expression

bromobenzene results in increased expression of SASH1 mRNA

NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870

G

stabilizer of axonemal microtubules 2

increases expression

bromobenzene results in increased expression of SAXO2 mRNA

NCBI chr 1:136,596,445...136,638,444
Ensembl chr 1:136,623,493...136,638,454

G

Sbds, ribosome maturation factor

decreases expression

bromobenzene results in decreased expression of SBDS mRNA

NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649

G

sterol-C5-desaturase

decreases expression

bromobenzene results in decreased expression of SC5D mRNA

NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273

G

stearoyl-CoA desaturase

decreases expression
increases expression

bromobenzene results in decreased expression of SCD1 mRNA
bromobenzene results in increased expression of SCD mRNA

PMID:15976192 PMID:32479839

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

sodium voltage-gated channel beta subunit 4

increases expression

bromobenzene results in increased expression of SCN4B mRNA

NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292

G

sodium channel epithelial 1 subunit alpha

increases expression

bromobenzene results in increased expression of SCNN1A mRNA

NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181

G

syndecan 4

increases expression

bromobenzene results in increased expression of SDC4 mRNA

NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580

G

serine dehydratase

increases expression

bromobenzene results in increased expression of SDS mRNA

NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203

G

SEBOX homeobox

decreases expression

bromobenzene results in decreased expression of SEBOX mRNA

NCBI chr10:63,399,215...63,400,086
Ensembl chr10:63,399,165...63,400,606

G

selenium binding protein 1

affects binding

bromobenzene metabolite binds to SELENBP1 protein

NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594

G

selenoprotein P

decreases expression

bromobenzene results in decreased expression of SELENOP mRNA

NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852

G

selectin L

decreases expression

bromobenzene results in decreased expression of SELL mRNA

NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456

G

semaphorin 6B

increases expression

bromobenzene results in increased expression of SEMA6B mRNA

NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521

G

sestrin 2

increases expression

bromobenzene results in increased expression of SESN2 mRNA

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

G

SET binding protein 1

increases expression

bromobenzene results in increased expression of SETBP1 mRNA

NCBI chr18:72,190,542...72,551,272
Ensembl chr18:72,191,035...72,552,556

G

serum/glucocorticoid regulated kinase 1

increases expression

bromobenzene results in increased expression of SGK1 mRNA

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

serum/glucocorticoid regulated kinase 2

decreases expression

bromobenzene results in decreased expression of SGK2 mRNA

NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480

G

SH2 domain containing 4A

decreases expression

bromobenzene results in decreased expression of SH2D4A mRNA

NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260

G

SH3 and PX domains 2B

increases expression

bromobenzene results in increased expression of SH3PXD2B mRNA

NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170

G

SID1 transmembrane family, member 1

increases expression

bromobenzene results in increased expression of SIDT1 mRNA

NCBI chr11:56,362,788...56,459,939
Ensembl chr11:56,363,512...56,459,050

G

SLAM family member 6

increases expression

bromobenzene results in increased expression of SLAMF6 mRNA

NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300

G

solute carrier family 10 member 2

decreases expression

bromobenzene results in decreased expression of SLC10A2 mRNA

NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475

G

solute carrier family 10 member 6

increases expression

bromobenzene results in increased expression of SLC10A6 mRNA

NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037

G

solute carrier family 11 member 1

decreases expression

bromobenzene results in decreased expression of SLC11A1 mRNA

NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101

G

solute carrier family 13 member 2

decreases expression

bromobenzene results in decreased expression of SLC13A2 mRNA

NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127

G

solute carrier family 13 member 4

decreases expression

bromobenzene results in decreased expression of SLC13A4 mRNA

NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857

G

solute carrier family 13 member 5

increases expression

bromobenzene results in increased expression of SLC13A5 mRNA

NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945

G

solute carrier family 15 member 4

increases expression

bromobenzene results in increased expression of SLC15A4 mRNA

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

G

solute carrier family 16 member 5

increases expression

bromobenzene results in increased expression of SLC16A5 mRNA

NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338

G

solute carrier family 17 member 9

decreases expression

bromobenzene results in decreased expression of SLC17A9 mRNA

NCBI chr 3:167,839,246...167,857,462
Ensembl chr 3:167,839,385...167,855,985

G

solute carrier family 19 member 2

decreases expression

bromobenzene results in decreased expression of SLC19A2 mRNA

NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172

G

solute carrier family 1 member 3

affects expression

bromobenzene affects the expression of SLC1A3 mRNA

NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605

G

solute carrier family 1 member 4

increases expression

bromobenzene results in increased expression of SLC1A4 mRNA

NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418

G

solute carrier family 22 member 5

increases expression

bromobenzene results in increased expression of SLC22A5 mRNA

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

G

solute carrier family 25 member 15

increases expression

bromobenzene results in increased expression of SLC25A15 mRNA

NCBI chr16:69,631,581...69,654,869
Ensembl chr16:69,634,414...69,653,010

G

solute carrier family 25 member 25

increases expression

bromobenzene results in increased expression of SLC25A25 mRNA

NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216

G

solute carrier family 25, member 27

increases expression

bromobenzene results in increased expression of SLC25A27 mRNA

NCBI chr 9:17,306,898...17,333,942
Ensembl chr 9:17,307,023...17,332,731

G

solute carrier family 25 member 29

increases expression

bromobenzene results in increased expression of SLC25A29 mRNA

NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940

G

solute carrier family 25, member 30

decreases expression

bromobenzene results in decreased expression of SLC25A30 mRNA

NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613

G

solute carrier family 25 member 32

increases expression

bromobenzene results in increased expression of SLC25A32 mRNA

NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:70,142,964...70,160,770

G

solute carrier family 29 member 4

decreases expression

bromobenzene results in decreased expression of SLC29A4 mRNA

NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834

G

solute carrier family 2 member 1

increases expression

bromobenzene results in increased expression of SLC2A1 mRNA

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 34 member 2

decreases expression

bromobenzene results in decreased expression of SLC34A2 mRNA

NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436

G

solute carrier family 35, member G1

increases expression

bromobenzene results in increased expression of SLC35G1 mRNA

NCBI chr 1:236,163,593...236,172,115
Ensembl chr 1:236,163,175...236,170,262

G

solute carrier family 38, member 2

increases expression

bromobenzene results in increased expression of SLC38A2 mRNA

NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436

G

solute carrier family 43 member 1

decreases expression

bromobenzene results in decreased expression of SLC43A1 mRNA

NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768

G

solute carrier family 44, member 3

increases expression

bromobenzene results in increased expression of SLC44A3 mRNA

NCBI chr 2:209,552,138...209,628,182
Ensembl chr 2:209,552,144...209,629,044

G

solute carrier family 45, member 3

decreases expression

bromobenzene results in decreased expression of SLC45A3 mRNA

NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588

G

solute carrier family 4 member 11

decreases expression

bromobenzene results in decreased expression of SLC4A11 mRNA

NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674

G

solute carrier family 4 member 4

increases expression

bromobenzene results in increased expression of SLC4A4 mRNA

NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883

G

solute carrier family 4 member 5

increases expression

bromobenzene results in increased expression of SLC4A5 mRNA

NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323

G

solute carrier family 51 member A

increases expression

bromobenzene results in increased expression of SLC51A mRNA

NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485

G

solute carrier family 5 member 8

increases expression

bromobenzene results in increased expression of SLC5A8 mRNA

NCBI chr 7:23,272,891...23,313,811
Ensembl chr 7:23,272,427...23,314,642

G

solute carrier family 6 member 14

increases expression

bromobenzene results in increased expression of SLC6A14 mRNA

NCBI chr X:112,314,643...112,375,412
Ensembl chr X:112,314,691...112,375,096

G

solute carrier family 6 member 6

increases expression

bromobenzene results in increased expression of SLC6A6 mRNA

NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875

G

solute carrier family 7 member 1

increases expression

bromobenzene results in increased expression of SLC7A1 mRNA

NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849

G

solute carrier family 7 member 11

increases expression

bromobenzene results in increased expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

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solute carrier organic anion transporter family, member 1a4

decreases expression

bromobenzene results in decreased expression of SLCO1A4 mRNA

PMID:15976192 PMID:32479839

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

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solute carrier organic anion transporter family, member 1c1

increases expression

bromobenzene results in increased expression of SLCO1C1 mRNA

NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289

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slit guidance ligand 1

increases expression

bromobenzene results in increased expression of SLIT1 mRNA

NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127

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SLIT and NTRK-like family, member 1

increases expression

bromobenzene results in increased expression of SLITRK1 mRNA

NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509

G

spermine oxidase

increases expression

bromobenzene results in increased expression of SMOX mRNA

NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710

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syntrophin, beta 1

increases expression

bromobenzene results in increased expression of SNTB1 mRNA

NCBI chr 7:87,060,926...87,329,315
Ensembl chr 7:87,060,926...87,329,315

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superoxide dismutase 1

affects binding

bromobenzene metabolite binds to SOD1 protein

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

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sorbitol dehydrogenase

increases activity

bromobenzene results in increased activity of SORD protein

NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133

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speedy/RINGO cell cycle regulator family member A

decreases expression

bromobenzene results in decreased expression of SPDYA mRNA

NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850

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Spi-B transcription factor

decreases expression

bromobenzene results in decreased expression of SPIB mRNA

NCBI chr 1:95,018,939...95,024,804
Ensembl chr 1:95,018,947...95,024,780

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SREBF pathway regulator in golgi 1

increases expression

bromobenzene results in increased expression of SPRING1 mRNA

NCBI chr12:38,306,227...38,329,175
Ensembl chr12:38,297,837...38,329,138

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splA/ryanodine receptor domain and SOCS box containing 1

increases expression

bromobenzene results in increased expression of SPSB1 mRNA

NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468

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splA/ryanodine receptor domain and SOCS box containing 4

increases expression

bromobenzene results in increased expression of SPSB4 mRNA

NCBI chr 8:97,536,519...97,609,757
Ensembl chr 8:97,536,520...97,609,787

G

squalene epoxidase

decreases expression

bromobenzene results in decreased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

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sterol regulatory element binding transcription factor 1

decreases expression

bromobenzene results in decreased expression of SREBF1 mRNA

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

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signal recognition particle 68

increases expression

bromobenzene results in increased expression of SRP68 mRNA

NCBI chr10:101,481,213...101,508,035
Ensembl chr10:101,481,212...101,508,035

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somatostatin receptor 3

increases expression

bromobenzene results in increased expression of SSTR3 mRNA

NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769

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ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

increases expression

bromobenzene results in increased expression of ST8SIA1 mRNA

NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708

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SH3 and cysteine rich domain 3

decreases expression

bromobenzene results in decreased expression of STAC3 mRNA

NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589

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StAR-related lipid transfer domain containing 4

decreases expression

bromobenzene results in decreased expression of STARD4 mRNA

NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024

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stanniocalcin 1

decreases expression

bromobenzene results in decreased expression of STC1 mRNA

NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264

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STEAP2 metalloreductase

increases expression

bromobenzene results in increased expression of STEAP2 mRNA

NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791

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stomatin like 3

increases expression

bromobenzene results in increased expression of STOML3 mRNA

NCBI chr 2:137,572,691...137,582,402
Ensembl chr 2:137,572,691...137,590,681

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syntaxin binding protein 5L

increases expression

bromobenzene results in increased expression of STXBP5L mRNA

NCBI chr11:63,334,667...63,654,270
Ensembl chr11:63,334,667...63,657,014

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sulfotransferase family 1B member 1

affects binding

bromobenzene metabolite binds to SULT1B1 protein

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

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sulfotransferase family 1C member 3

decreases expression

bromobenzene results in decreased expression of SULT1C1 mRNA

NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030

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SV2 related protein

increases expression

bromobenzene results in increased expression of SVOP mRNA

NCBI chr12:42,530,991...42,589,381
Ensembl chr12:42,531,032...42,590,572

G

synaptojanin 2

decreases expression

bromobenzene results in decreased expression of SYNJ2 mRNA

NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687

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synaptoporin

decreases expression

bromobenzene results in decreased expression of SYNPR mRNA

NCBI chr15:11,573,373...11,900,255
Ensembl chr15:11,574,231...11,900,243

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synaptophysin-like 1

increases expression

bromobenzene results in increased expression of SYPL1 mRNA

NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330

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synaptotagmin 2

decreases expression

bromobenzene results in decreased expression of SYT2 mRNA

NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859

G

TATA-box binding protein associated factor 9b

increases expression

bromobenzene results in increased expression of TAF9B mRNA

NCBI chr X:71,289,290...71,300,142
Ensembl chr X:71,289,290...71,300,604

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tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

increases expression

bromobenzene results in increased expression of TANC1 mRNA

NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627

G

tyrosine aminotransferase

increases expression

bromobenzene results in increased expression of TAT mRNA

NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031

G

T-box transcription factor 3

increases expression

bromobenzene results in increased expression of TBX3 mRNA

NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708

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transcription elongation factor A3

decreases expression

bromobenzene results in decreased expression of TCEA3 mRNA

NCBI chr 5:148,476,941...148,509,452
Ensembl chr 5:148,476,941...148,509,448

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transcriptional and immune response regulator

increases expression

bromobenzene results in increased expression of TCIM mRNA

NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581

G

tudor domain containing 1

increases expression

bromobenzene results in increased expression of TDRD1 mRNA

NCBI chr 1:255,871,939...255,919,222
Ensembl chr 1:255,875,887...255,915,871

G

tektin 4

increases expression

bromobenzene results in increased expression of TEKT4 mRNA

NCBI chr10:14,487,760...14,492,936
Ensembl chr10:14,487,760...14,492,936

G

teneurin transmembrane protein 2

decreases expression

bromobenzene results in decreased expression of TENM2 mRNA

NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597

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testis expressed 36

increases expression

bromobenzene results in increased expression of TEX36 mRNA

NCBI chr 1:188,390,062...188,404,448
Ensembl chr 1:188,390,064...188,404,377

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testis expressed 52

increases expression

bromobenzene results in increased expression of TEX52 mRNA

NCBI chr 4:161,651,232...161,663,250
Ensembl chr 4:161,638,816...161,660,540

G

transferrin

decreases expression

bromobenzene results in decreased expression of TF mRNA

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

G

transcription factor CP2

increases expression

bromobenzene results in increased expression of TFCP2 mRNA

NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939

G

thyroglobulin

decreases expression

bromobenzene results in decreased expression of TG mRNA

NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210

G

thrombospondin 4

increases expression

bromobenzene results in increased expression of THBS4 mRNA

NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313

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thyroid hormone receptor alpha

decreases expression

bromobenzene results in decreased expression of THRA mRNA

NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936

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thyroid hormone responsive

decreases expression

bromobenzene results in decreased expression of THRSP mRNA

NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075

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thrombospondin type 1 domain containing 7B

increases expression

bromobenzene results in increased expression of THSD7B mRNA

NCBI chr13:40,768,567...41,667,262
Ensembl chr13:40,768,570...41,666,501

G

timeless circadian regulator

decreases expression

bromobenzene results in decreased expression of TIMELESS mRNA

NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738

G

TIMP metallopeptidase inhibitor 1

increases expression

bromobenzene results in increased expression of TIMP1 mRNA

PMID:12628495 PMID:15056800

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

toll-like receptor 5

increases expression

bromobenzene results in increased expression of TLR5 mRNA

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

G

transmembrane protein 179

increases expression

bromobenzene results in increased expression of TMEM179 mRNA

NCBI chr 6:131,569,289...131,580,413
Ensembl chr 6:131,569,290...131,580,305

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transmembrane protein 252

increases expression

bromobenzene results in increased expression of TMEM252 mRNA

NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943

G

transmembrane protein 26

increases expression

bromobenzene results in increased expression of TMEM26 mRNA

NCBI chr20:19,820,768...19,872,561
Ensembl chr20:19,822,975...19,872,023

G

transmembrane protein 30B

increases expression

bromobenzene results in increased expression of TMEM30B mRNA

NCBI chr 6:92,251,626...92,254,702
Ensembl chr 6:92,249,790...92,254,842

G

transmembrane serine protease 13

increases expression

bromobenzene results in increased expression of TMPRSS13 mRNA

NCBI chr 8:45,625,759...45,653,943
Ensembl chr 8:45,625,626...45,653,938

G

thymosin, beta 10

decreases expression

bromobenzene results in decreased expression of TMSB10 mRNA

NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028

G

TNF alpha induced protein 2

decreases expression

bromobenzene results in decreased expression of TNFAIP2 mRNA

NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914

G

TNF alpha induced protein 8 like 3

decreases expression

bromobenzene results in decreased expression of TNFAIP8L3 mRNA

NCBI chr 8:54,413,503...54,455,512
Ensembl chr 8:54,414,457...54,500,079

G

TNF receptor superfamily member 11A

increases expression

bromobenzene results in increased expression of TNFRSF11A mRNA

NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695

G

TNF receptor superfamily member 4

increases expression

bromobenzene results in increased expression of TNFRSF4 mRNA

NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599

G

troponin C2, fast skeletal type

increases expression

bromobenzene results in increased expression of TNNC2 mRNA

NCBI chr 3:153,513,272...153,516,033
Ensembl chr 3:153,513,271...153,516,029

G

trinucleotide repeat containing adaptor 6A

increases expression

bromobenzene results in increased expression of TNRC6A mRNA

NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660

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TOG array regulator of axonemal microtubules 2

decreases expression

bromobenzene results in decreased expression of TOGARAM2 mRNA

NCBI chr 6:23,770,979...23,828,884
Ensembl chr 6:23,771,052...23,828,499

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target of myb1 like 2 membrane trafficking protein

increases expression

bromobenzene results in increased expression of TOM1L2 mRNA

NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032

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tonsoku-like, DNA repair protein

decreases expression