fluorometholone - Ontology Report

Fluorometholone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Casp3

caspase 3

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased activity of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

Cdkn1a

cyclin-dependent kinase inhibitor 1A

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased expression of CDKN1A protein]

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

coagulation factor III, tissue factor

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased expression of F3 mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased expression of F3 protein]

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

Glb1

galactosidase, beta 1

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fluorometholone inhibits the reaction [Glucose results in increased activity of GLB1 protein]]; Fluorometholone inhibits the reaction [Glucose results in increased activity of GLB1 protein]

NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127

Il6

interleukin 6

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased secretion of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Rb1

RB transcriptional corepressor 1

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased expression of RB1 protein]

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

Slc22a2

solute carrier family 22 member 2

multiple interactions

Fluorometholone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]

PMID:21599003

NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268

Tert

telomerase reverse transcriptase

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in decreased activity of TERT protein]

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

Tnf

tumor necrosis factor

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased secretion of TNF protein]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Tp53

tumor protein p53

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fluorometholone inhibits the reaction [Glucose results in increased expression of TP53 protein]]; Fluorometholone inhibits the reaction [Glucose results in increased expression of TP53 protein]

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

Vegfa

vascular endothelial growth factor A

multiple interactions

Fluorometholone inhibits the reaction [Glucose results in increased expression of VEGFA mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased expression of VEGFA protein]