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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethylestrenol
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Accession:CHEBI:31578 term browser browse the term
Definition:A 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used to promote growth in boys with delayed bone growth.
Synonyms:exact_synonym: (17alpha)-19-norpregn-4-en-17-ol
 related_synonym: 17alpha-ethyl-17beta-hydroxy-4-estrene;   17alpha-ethylestr-4-en-17beta-ol;   17beta-hydroxy-17alpha-ethyl-19-nor-4-androstene;   19-nor-17alpha-pregn-4-en-17beta-ol;   Durabolin-O;   Duraboral;   Formula=C20H32O;   InChI=1S/C20H32O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h6,15-18,21H,3-5,7-13H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1;   InChIKey=AOXRBFRFYPMWLR-XGXHKTLJSA-N;   Maxibalin;   Maxibolin;   Neodurabolin;   Orabolin;   Orgabolin;   Orgaboral;   SMILES=CC[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCC[C@@H]4[C@H]3CC[C@]12C;   ethylestrenolum;   ethylnandrol;   etilestrenol
 xref: CAS:965-90-2;   DrugBank:DB01493;   Drug_Central:1094;   KEGG:D01414
 xref_mesh: MESH:D005032
 xref: PMID:10406207;   PMID:14001307;   PMID:14482850;   PMID:3865482;   PMID:637620;   PMID:7193965;   PMID:7233967;   PMID:7233968;   Patent:US2878267;   Reaxys:3140841;   Wikipedia:Ethylestrenol


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ethylestrenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Ethylestrenol inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        molecular messenger 18659
          hormone 18489
            anabolic agent 495
              ethylestrenol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic polycyclic compound 17286
                                  steroid 14717
                                    hydroxy steroid 14466
                                      17-hydroxy steroid 14107
                                        17beta-hydroxy steroid 13363
                                          ethylestrenol 1
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