ethylenediamine derivative - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	ethylenediamine derivative	go back to main search page
Accession:	CHEBI:31577	browse the term
Definition:	Any organic amino compound that is a derivative of ethylenediamine.
Synonyms:	related_synonym:	ethylenediamine derivatives
	cyclic_relationship:	has_functional_parent CHEBI:30347

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Rat (3599 ) Mouse (3576 ) Human (3919 ) Chinchilla (0 ) Bonobo (0 ) Dog (0 ) Squirrel (0 ) Pig (2 ) Green Monkey (0) Naked Mole-rat (0 ) All
Genes (3599)

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

multiple interactions

ISO

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of ABCB11 protein

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581

G

ATP binding cassette subfamily C member 2

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of ABCC2 protein

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

angiotensin converting enzyme 2

increases expression

ISO

Ethambutol results in increased expression of ACE2 mRNA

NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596

G

acyl-CoA synthetase long-chain family member 4

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein

NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261

G

bone morphogenetic protein 6

decreases expression

ISO

Ethambutol results in decreased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261

G

caspase 3

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of CASP3

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

catalase

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of CAT protein; [isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in decreased activity of CAT protein

PMID:34118364 PMID:36878459

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

C-C motif chemokine ligand 2

affects expression

EXP

Ethambutol affects the expression of CCL2 mRNA

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 5

affects expression

EXP

Ethambutol affects the expression of CCL5 protein

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

cathepsin D

multiple interactions

EXP

Ethambutol results in increased expression of and affects the localization of CTSD protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Ethambutol results in increased expression of and affects the localization of CTSD protein]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases activity

ISO

Ethambutol results in decreased activity of CYP1A2 protein

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 2, subfamily c, polypeptide 23

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2C23 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2C23 mRNA]

NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases activity

ISO

Ethambutol results in decreased activity of CYP2C19 protein

NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases activity

ISO

Ethambutol results in decreased activity of CYP2D6 protein

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases activity
increases expression
multiple interactions

ISO
EXP

Ethambutol results in decreased activity of CYP2E1 protein
Ethambutol results in increased expression of CYP2E1 mRNA
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein; [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Ethambutol results in increased expression of and results in increased activity of CYP2E1 protein; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]

PMID:24910189 PMID:27334974 PMID:27919644

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions

ISO
EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of CYP7A1 protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of CYP7A1 protein

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

glutamic--pyruvic transaminase

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPT protein; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein]

PMID:35835356 PMID:36878459

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 4

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein]

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629

G

granzyme B

increases secretion

ISO

Ethambutol results in increased secretion of GZMB protein

NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469

G

hypoxia inducible factor 1 subunit alpha

multiple interactions

EXP

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of HIF1A mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of HIF1A protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein]; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein]; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein]

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

interferon gamma

increases secretion

ISO

Ethambutol results in increased secretion of IFNG protein

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interleukin 10

decreases expression

EXP

Ethambutol results in decreased expression of IL10 protein

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 13

increases secretion

ISO

Ethambutol results in increased secretion of IL13 protein

NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483

G

interleukin 1 alpha

increases expression

ISO

Ethambutol results in increased expression of IL1A mRNA

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

decreases expression

EXP

Ethambutol results in decreased expression of IL1B mRNA

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

decreases expression

EXP

Ethambutol results in decreased expression of IL6 protein

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

lysosomal-associated membrane protein 2

increases expression
multiple interactions

EXP

Ethambutol results in increased expression of LAMP2 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Ethambutol results in increased expression of LAMP2 protein]

NCBI chr X:122,038,734...122,087,745
Ensembl chr X:121,922,187...122,087,675

G

leptin

decreases expression

EXP

Ethambutol results in decreased expression of LEP protein

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

MET proto-oncogene, receptor tyrosine kinase

increases expression

ISO

Ethambutol results in increased expression of MET mRNA

NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821

G

myeloperoxidase

multiple interactions

EXP

[efavirenz co-treated with Lamivudine co-treated with Tenofovir] promotes the reaction [[isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein]; [isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

nuclear receptor subfamily 1, group H, member 4

multiple interactions

EXP
ISO

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of NR1H4

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389

G

phosphotyrosine interaction domain containing 1

increases expression

ISO

Ethambutol results in increased expression of PID1 mRNA

NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070

G

solute carrier family 10 member 1

multiple interactions

ISO

[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of SLC10A1

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944

G

solute carrier family 7 member 11

increases expression
multiple interactions

ISO
EXP

Ethambutol results in increased expression of SLC7A11 mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein]

PMID:32816093 PMID:36878459

NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695

G

secretory leukocyte peptidase inhibitor

increases expression

ISO

Ethambutol results in increased expression of SLPI mRNA

NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822

ethylenediaminetetraacetic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

decreases activity
multiple interactions

ISO

Edetic Acid results in decreased activity of ACE protein
Zinc Sulfate inhibits the reaction [Edetic Acid results in decreased activity of ACE protein]

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

acetylcholinesterase

multiple interactions

ISO

Edetic Acid results in decreased metabolism of and results in decreased secretion of ACHE protein

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

aryl hydrocarbon receptor

multiple interactions

EXP

Edetic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

alanyl aminopeptidase, membrane

multiple interactions

ISO

Edetic Acid promotes the reaction [1,10-phenanthroline results in decreased activity of ANPEP protein]

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

amyloid beta precursor like protein 1

multiple interactions

ISO

Edetic Acid inhibits the reaction [Zinc affects the localization of APLP1 protein]

NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:94,824,072...94,834,610

G

amyloid beta precursor like protein 2

multiple interactions

ISO

Edetic Acid inhibits the reaction [Zinc affects the localization of APLP2 protein]

NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031

G

amyloid beta precursor protein

multiple interactions

ISO

Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

aspartoacylase

decreases activity

ISO

Edetic Acid results in decreased activity of ASPA protein

NCBI chr10:58,390,204...58,443,790
Ensembl chr10:58,379,410...58,443,769

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

multiple interactions

EXP

[ferrous sulfate co-treated with Edetic Acid] results in decreased activity of ATP2A1 protein; Butylated Hydroxytoluene inhibits the reaction [[ferrous sulfate co-treated with Edetic Acid] results in decreased activity of ATP2A1 protein]; dicarbine inhibits the reaction [[ferrous sulfate co-treated with Edetic Acid] results in decreased activity of ATP2A1 protein]

NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:190,457,198...190,475,423

G

bone morphogenetic protein 4

multiple interactions

ISO

[Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172

G

caspase 1

multiple interactions

ISO

Edetic Acid inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

catalase

multiple interactions

ISO

CAT inhibits the reaction [[XDH protein co-treated with Edetic Acid analog] results in increased oxidation of Uroporphyrinogens]

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

ceruloplasmin

multiple interactions

ISO

Edetic Acid inhibits the reaction [CP protein results in increased oxidation of 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl]

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

EXP

Edetic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

ISO

Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

dihydrolipoamide dehydrogenase

multiple interactions

ISO

Edetic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of and results in increased phosphorylation of DLD protein]

NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354

G

dentin sialophosphoprotein

affects localization

EXP

Edetic Acid affects the localization of DSPP protein

NCBI chr14:5,870,232...5,876,339
Ensembl chr14:5,870,232...5,876,339

G

dual specificity phosphatase 23

multiple interactions

ISO

Edetic Acid inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate]

NCBI chr13:87,630,245...87,632,400
Ensembl chr13:87,630,245...87,632,400

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

multiple interactions

ISO

Edetic Acid inhibits the reaction [Zinc results in decreased activity of ENPP7 protein]

NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,740,763...104,745,760

G

estrogen receptor 1

increases expression

ISO

Edetic Acid results in increased expression of ESR1 mRNA

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

growth hormone 1

multiple interactions

EXP

Edetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]

NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859

G

insulin-like growth factor binding protein 5

decreases degradation

EXP

Edetic Acid results in decreased degradation of IGFBP5 protein

NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390

G

interleukin 6

multiple interactions

ISO

Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

integrin subunit alpha M

increases expression

ISO

Edetic Acid results in increased expression of ITGAM protein

NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943

G

Kelch-like ECH-associated protein 1

multiple interactions

ISO

Edetic Acid promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein]

NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042

G

myelin basic protein

affects expression

EXP

Edetic Acid affects the expression of MBP mRNA

NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174

G

matrix Gla protein

multiple interactions

ISO

[Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein]

NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859

G

matrix metallopeptidase 8

decreases activity

ISO

Edetic Acid results in decreased activity of MMP8 protein

NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729

G

metallothionein 1A

multiple interactions

ISO

Edetic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 3

increases alkylation
affects metabolic processing

ISO

Edetic Acid results in increased alkylation of MT3 protein
MT3 protein polymorphism affects the metabolism of Edetic Acid

PMID:12383939 PMID:14983064

NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,854,677...10,856,080

G

nei-like DNA glycosylase 1

multiple interactions

ISO

[tris(2-carboxyethyl)phosphine co-treated with Edetic Acid] inhibits the reaction [Copper results in decreased activity of NEIL1 protein]; Edetic Acid inhibits the reaction [Iron binds to and results in decreased activity of NEIL1 protein]

NCBI chr 8:66,446,106...66,452,844
Ensembl chr 8:66,445,953...66,452,378

G

opticin

multiple interactions

ISO

Edetic Acid inhibits the reaction [Oxygen deficiency results in increased degradation of OPTC protein]; Edetic Acid inhibits the reaction [VEGFA protein results in increased degradation of OPTC protein]

NCBI chr13:47,906,145...47,920,334
Ensembl chr13:47,906,197...47,917,416

G

phosphoglycolate phosphatase

decreases activity

ISO

Edetic Acid results in decreased activity of PGP protein

NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408

G

plasminogen activator, tissue type

multiple interactions

ISO

Edetic Acid inhibits the reaction [Zinc results in increased expression of PLAT mRNA]; Edetic Acid inhibits the reaction [Zinc results in increased expression of PLAT protein]; Edetic Acid inhibits the reaction [Zinc results in increased secretion of PLAT protein]

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696

G

plasminogen

multiple interactions

ISO

Edetic Acid inhibits the reaction [Zinc results in increased expression of PLG mRNA]; Edetic Acid inhibits the reaction [Zinc results in increased expression of PLG protein]

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

prolactin

multiple interactions

ISO

Edetic Acid inhibits the reaction [PRL protein binds to PRLR protein]

NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217

G

prolactin receptor

multiple interactions

ISO

Edetic Acid inhibits the reaction [PRL protein binds to PRLR protein]

NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882

G

prion protein

multiple interactions

ISO

Edetic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Copper] results in increased cleavage of PRNP protein]; Edetic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Iron] results in increased cleavage of PRNP protein]

NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436

G

S100 calcium binding protein A2

multiple interactions

ISO

Edetic Acid inhibits the reaction [Copper promotes the reaction [S100A2 protein binds to S100A2 protein]]; Edetic Acid inhibits the reaction [S100A2 protein binds to S100A2 protein]

NCBI chr 2:178,374,659...178,375,903

G

S100 calcium-binding protein A4

multiple interactions

ISO

Edetic Acid inhibits the reaction [Copper promotes the reaction [S100A4 protein binds to S100A4 protein]]

NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837

G

selectin L

decreases expression

ISO

Edetic Acid results in decreased expression of SELL protein

NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600

G

solute carrier family 30, member 10

increases expression
multiple interactions

ISO

Edetic Acid results in increased expression of SLC30A10 mRNA; Edetic Acid results in increased expression of SLC30A10 protein
Edetic Acid inhibits the reaction [SLC30A10 gene mutant form results in increased abundance of Manganese]

PMID:22341971 PMID:22926781

NCBI chr13:99,529,664...99,584,442
Ensembl chr13:99,529,790...99,544,213

G

spectrin, alpha, non-erythrocytic 1

multiple interactions

EXP

Edetic Acid inhibits the reaction [Calcium results in increased cleavage of SPTAN1 protein]

NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889

G

serine racemase

multiple interactions

ISO

Adenosine Triphosphate inhibits the reaction [Edetic Acid inhibits the reaction [SRR protein results in increased abundance of D-Aspartic Acid]]; Edetic Acid inhibits the reaction [SRR protein results in increased abundance of D-Aspartic Acid]

NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100

G

tumor necrosis factor

increases expression

ISO

Edetic Acid results in increased expression of TNF protein

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

tumor protein p53

multiple interactions

ISO

Edetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]]; Edetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]]; Edetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]]

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein p63

multiple interactions

ISO

Edetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]]

NCBI chr11:88,343,647...88,554,543
Ensembl chr11:88,343,651...88,554,177

G

tumor protein p73

multiple interactions

ISO

Edetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]]

NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552

G

transient receptor potential cation channel, subfamily V, member 1

multiple interactions

ISO

Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021

G

thioredoxin reductase 1

increases activity
multiple interactions

ISO

Edetic Acid results in increased activity of TXNRD1 protein
Zinc inhibits the reaction [Edetic Acid results in increased activity of TXNRD1 protein]

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817

G

thioredoxin reductase 3

increases activity
multiple interactions

ISO

Edetic Acid results in increased activity of TXNRD3 protein
Zinc inhibits the reaction [Edetic Acid results in increased activity of TXNRD3 protein]

NCBI chr 4:123,629,768...123,669,713
Ensembl chr 4:123,648,750...123,668,552

G

vascular endothelial growth factor A

multiple interactions

ISO

Edetic Acid inhibits the reaction [VEGFA protein results in increased degradation of OPTC protein]

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

xanthine dehydrogenase

multiple interactions

ISO

[XDH protein co-treated with Edetic Acid analog] results in increased oxidation of Uroporphyrinogens; CAT inhibits the reaction [[XDH protein co-treated with Edetic Acid analog] results in increased oxidation of Uroporphyrinogens]

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

butyrylcholinesterase

decreases activity

ISO

Pyrilamine results in decreased activity of BCHE protein

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760

G

coagulation factor III, tissue factor

multiple interactions

ISO

Pyrilamine inhibits the reaction [Histamine results in increased activity of F3 protein]; Pyrilamine inhibits the reaction [Histamine results in increased expression of F3]

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

histamine receptor H 1

multiple interactions
decreases activity
affects binding

ISO
EXP

Diphenhydramine inhibits the reaction [Pyrilamine binds to HRH1 protein]; diphenylpyraline inhibits the reaction [Pyrilamine binds to HRH1 protein]; Guanosine Triphosphate analog affects the reaction [Histamine inhibits the reaction [Pyrilamine binds to HRH1 protein]]; Histamine inhibits the reaction [Pyrilamine binds to HRH1 protein]; HRH1 protein promotes the reaction [Pyrilamine results in decreased susceptibility to CXCL8 protein]; Lipopolysaccharides promotes the reaction [Pyrilamine binds to HRH1 protein]; Promethazine inhibits the reaction [Pyrilamine binds to HRH1 protein]; Triprolidine inhibits the reaction [Pyrilamine binds to HRH1 protein]
Pyrilamine results in decreased activity of HRH1 protein
8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [Pyrilamine binds to HRH1 protein]; [Pyrilamine binds to and results in decreased activity of HRH1 protein] which results in decreased susceptibility to clobenpropit; Pyrilamine binds to and results in decreased activity of HRH1 protein; Pyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in decreased susceptibility to Scopolamine]; Pyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]; Tacrine inhibits the reaction [Pyrilamine binds to HRH1 protein]; Toluene 2,4-Diisocyanate promotes the reaction [Pyrilamine binds to HRH1 protein]

PMID:1912125 PMID:2419744 PMID:2606156 PMID:3379823 PMID:7522859 More...

NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:149,120,039...149,208,248

G

potassium voltage-gated channel subfamily H member 2

multiple interactions
affects activity

ISO

Pyrilamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Pyrilamine affects the activity of KCNH2 protein

PMID:16278312 PMID:21158687

NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421

G

kininogen 1

decreases activity

ISO

Pyrilamine results in decreased activity of KNG1 protein

NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148

G

mitogen activated protein kinase 1

multiple interactions

ISO

Pyrilamine inhibits the reaction [Histamine results in increased phosphorylation of and results in increased activity of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

ISO

Pyrilamine inhibits the reaction [Histamine results in increased phosphorylation of and results in increased activity of MAPK3 protein]

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

nerve growth factor

multiple interactions

EXP

Pyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased expression of NGF protein]

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834

G

neurotrophin 3

multiple interactions

EXP

[Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; [Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Pyrilamine inhibits the reaction [Histamine results in increased expression of NTF3 protein]

NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349

G

solute carrier family 22 member 2

multiple interactions

ISO

Pyrilamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]

NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019

G

solute carrier family 22 member 5

multiple interactions

ISO

carebastine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Cyproheptadine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; ebastine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Promethazine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Promethazine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine; SLC22A5 protein affects the transport of and affects the abundance of Pyrilamine

NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077

G

solute carrier family 6 member 3

multiple interactions

ISO

Pyrilamine analog binds to and affects the activity of SLC6A3 protein

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962

G

solute carrier family 6 member 4

affects binding

ISO

Pyrilamine analog binds to SLC6A4 protein

NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

EXP

Methapyrilene results in decreased expression of A2M mRNA

NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868

G

aminoadipate aminotransferase

decreases expression

EXP

Methapyrilene results in decreased expression of AADAT mRNA

NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540

G

aminoadipate-semialdehyde synthase

decreases expression

EXP

Methapyrilene results in decreased expression of AASS mRNA

NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600

G

4-aminobutyrate aminotransferase

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of ABAT mRNA
Methapyrilene results in increased methylation of ABAT intron

PMID:16393664 PMID:23274394 PMID:30157460

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474

G

ATP binding cassette subfamily A member 1

decreases expression

EXP

Methapyrilene results in decreased expression of ABCA1 mRNA

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473

G

ATP binding cassette subfamily A member 3

increases methylation

ISO

Methapyrilene results in increased methylation of ABCA3 intron

NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285

G

ATP binding cassette subfamily B member 11

decreases expression

ISO

Methapyrilene results in decreased expression of ABCB11 mRNA

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581

G

ATP binding cassette subfamily B member 1A

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of ABCB1A mRNA
Methapyrilene results in decreased expression of ABCB1A mRNA

PMID:28935588 PMID:30467583

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP-binding cassette, sub-family B member 1B

increases expression

EXP

Methapyrilene results in increased expression of ABCB1B mRNA

PMID:15120968 PMID:23274394

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567

G

ATP binding cassette subfamily B member 4

increases expression
decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in increased expression of ABCB4 mRNA
Methapyrilene results in decreased expression of ABCB4 mRNA
Methapyrilene results in decreased methylation of ABCB4 intron

PMID:15120968 PMID:28935588 PMID:30157460

NCBI chr 4:26,106,895...26,164,440

G

ATP binding cassette subfamily C member 1

affects methylation

ISO

Methapyrilene affects the methylation of ABCC1 intron

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

ATP binding cassette subfamily C member 12

increases methylation

ISO

Methapyrilene results in increased methylation of ABCC12 intron

NCBI chr19:36,722,550...36,798,868
Ensembl chr19:36,722,575...36,793,993

G

ATP binding cassette subfamily C member 2

increases expression

EXP

Methapyrilene results in increased expression of ABCC2 mRNA

PMID:22484513 PMID:28529062

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

ATP binding cassette subfamily C member 3

increases expression
decreases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of ABCC3 mRNA
Methapyrilene results in decreased expression of ABCC3 mRNA
Methapyrilene results in increased methylation of ABCC3 intron

PMID:28935588 PMID:30157460

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494

G

ATP binding cassette subfamily C member 4

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of ABCC4 mRNA
Methapyrilene results in increased methylation of ABCC4 intron

PMID:28529062 PMID:30157460

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily C member 5

increases methylation

ISO

Methapyrilene results in increased methylation of ABCC5 intron

NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655

G

ATP binding cassette subfamily C member 8

increases methylation

ISO

Methapyrilene results in increased methylation of ABCC8 intron

NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982

G

ATP binding cassette subfamily D member 3

decreases expression

EXP

Methapyrilene results in decreased expression of ABCD3 mRNA

NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:212,536,791...212,590,504

G

ATP binding cassette subfamily E member 1

decreases expression

EXP

Methapyrilene results in decreased expression of ABCE1 mRNA

NCBI chr19:45,109,880...45,134,819
Ensembl chr19:45,109,906...45,134,819

G

ATP binding cassette subfamily G member 1

increases methylation

ISO

Methapyrilene results in increased methylation of ABCG1 intron

NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563

G

abhydrolase domain containing 10, depalmitoylase

increases expression

EXP

Methapyrilene results in increased expression of ABHD10 mRNA

NCBI chr11:68,543,860...68,556,059
Ensembl chr11:68,543,606...68,557,640

G

abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

increases expression

EXP

Methapyrilene results in increased expression of ABHD5 mRNA

NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947

G

abhydrolase domain containing 6, acylglycerol lipase

decreases expression

EXP

Methapyrilene results in decreased expression of ABHD6 mRNA

NCBI chr15:19,289,967...19,337,500
Ensembl chr15:19,289,969...19,337,193

G

abl-interactor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ABI1 intron

NCBI chr17:90,006,917...90,088,002
Ensembl chr17:90,006,925...90,087,827

G

ABL proto-oncogene 2, non-receptor tyrosine kinase

increases methylation

ISO

Methapyrilene results in increased methylation of ABL2 intron

NCBI chr13:71,223,902...71,319,770
Ensembl chr13:71,224,019...71,389,775

G

actin binding LIM protein family, member 2

affects methylation
increases methylation

ISO

Methapyrilene affects the methylation of ABLIM2 exon
Methapyrilene results in increased methylation of ABLIM2 intron

NCBI chr14:79,090,046...79,214,986
Ensembl chr14:79,090,923...79,214,972

G

actin binding LIM protein family, member 3

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of ABLIM3 intron
Methapyrilene results in decreased expression of ABLIM3 mRNA

PMID:30157460 PMID:30467583

NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710

G

ABR activator of RhoGEF and GTPase

affects methylation

ISO

Methapyrilene affects the methylation of ABR intron

NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,760,743...61,959,467

G

ankyrin repeat and BTB domain containing 3

increases methylation

ISO

Methapyrilene results in increased methylation of ABTB3 intron

NCBI chr 7:19,922,883...20,199,740
Ensembl chr 7:19,923,814...20,198,110

G

acetyl-CoA acyltransferase 1A

decreases expression

EXP

Methapyrilene results in decreased expression of ACAA1 mRNA

NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241

G

acetyl-CoA carboxylase alpha

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of ACACA intron
Methapyrilene results in decreased expression of ACACA mRNA

PMID:30157460 PMID:30467583

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acyl-CoA dehydrogenase family, member 11

decreases expression

EXP

Methapyrilene results in decreased expression of ACAD11 mRNA

NCBI chr 8:113,560,142...113,625,346
Ensembl chr 8:113,560,196...113,625,352

G

acyl-CoA dehydrogenase family, member 9

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of ACAD9 exon
Methapyrilene results in decreased expression of ACAD9 mRNA

PMID:30157460 PMID:30467583

NCBI chr 2:120,871,329...120,894,306
Ensembl chr 2:120,871,227...120,894,709

G

acyl-CoA dehydrogenase, long chain

decreases expression

EXP

Methapyrilene results in decreased expression of ACADL mRNA

NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164

G

acyl-CoA dehydrogenase short chain

decreases expression

EXP

Methapyrilene results in decreased expression of ACADS mRNA

NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103

G

acyl-CoA dehydrogenase, short/branched chain

decreases expression

EXP

Methapyrilene results in decreased expression of ACADSB mRNA

NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:195,619,038...195,660,561

G

acyl-CoA dehydrogenase, very long chain

decreases expression

EXP

Methapyrilene results in decreased expression of ACADVL mRNA

NCBI chr10:55,231,558...55,236,786
Ensembl chr10:55,231,440...55,236,750

G

acetyl-CoA acetyltransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ACAT1 mRNA

NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042

G

acetyl-CoA acetyltransferase 2

increases expression

EXP

Methapyrilene results in increased expression of ACAT2 mRNA

NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095

G

acyl-CoA binding domain containing 5

decreases expression

EXP

Methapyrilene results in decreased expression of ACBD5 mRNA

NCBI chr17:90,114,250...90,156,286
Ensembl chr17:90,114,375...90,156,286

G

alkaline ceramidase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ACER1 intron

NCBI chr 9:1,881,361...1,911,439
Ensembl chr 9:1,881,361...1,919,416

G

ATP citrate lyase

increases methylation

ISO

Methapyrilene results in increased methylation of ACLY exon

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631

G

aconitase 1

increases expression
decreases expression

EXP
ISO

Methapyrilene results in increased expression of ACO1 mRNA
Methapyrilene results in decreased expression of ACO1 mRNA

PMID:15890375 PMID:28935588 PMID:30467583

NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600

G

aconitase 2

decreases expression

EXP

Methapyrilene results in decreased expression of ACO2 protein

NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892

G

acyl-CoA thioesterase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ACOT1 polyA tail

NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749

G

acyl-CoA thioesterase 11

affects methylation

ISO

Methapyrilene affects the methylation of ACOT11 intron

NCBI chr 5:126,756,255...126,804,526
Ensembl chr 5:126,756,255...126,804,507

G

acyl-CoA thioesterase 12

decreases expression

EXP

Methapyrilene results in decreased expression of ACOT12 mRNA

NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298

G

acyl-CoA thioesterase 2

decreases expression

EXP

Methapyrilene results in decreased expression of ACOT2 mRNA

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502

G

acyl-CoA oxidase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ACOX1 intron

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136

G

acyl-CoA oxidase 2

decreases expression

EXP

Methapyrilene results in decreased expression of ACOX2 mRNA

PMID:28529062 PMID:30467583

NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392

G

acyl-CoA oxidase 3, pristanoyl

decreases methylation

ISO

Methapyrilene results in decreased methylation of ACOX3 intron

NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881

G

acyl-CoA synthetase bubblegum family member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ACSBG2 intron

NCBI chr 9:1,770,971...1,802,635
Ensembl chr 9:1,770,972...1,801,655

G

acyl-CoA synthetase long-chain family member 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of ACSL4 intron

NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261

G

acyl-CoA synthetase medium-chain family member 5

decreases expression

EXP

Methapyrilene results in decreased expression of ACSM5 mRNA

NCBI chr 1:183,302,241...183,328,175
Ensembl chr 1:183,294,105...183,329,925

G

actin, beta

decreases expression

EXP

Methapyrilene results in decreased expression of ACTB protein

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242

G

actin-like 6B

increases methylation

ISO

Methapyrilene results in increased methylation of ACTL6B intron

NCBI chr12:24,761,660...24,778,193
Ensembl chr12:24,761,693...24,778,151

G

actinin alpha 2

increases methylation

ISO

Methapyrilene results in increased methylation of ACTN2 intron

NCBI chr17:62,835,055...62,902,331
Ensembl chr17:62,812,988...62,903,552

G

actin related protein 10

increases methylation

ISO

Methapyrilene results in increased methylation of ACTR10 intron

NCBI chr 6:95,182,082...95,208,325
Ensembl chr 6:95,182,111...95,209,021

G

aminoacylase 3

decreases expression

EXP

Methapyrilene results in decreased expression of ACY3 mRNA

NCBI chr 1:210,709,238...210,715,258
Ensembl chr 1:210,709,294...210,715,633

G

ADAM metallopeptidase domain 10

decreases methylation

ISO

Methapyrilene results in decreased methylation of ADAM10 intron

NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600

G

ADAM metallopeptidase domain 11

increases methylation

ISO

Methapyrilene results in increased methylation of ADAM11 intron

NCBI chr10:88,224,185...88,242,865
Ensembl chr10:88,224,347...88,242,864

G

ADAM metallopeptidase domain 22

increases methylation

ISO

Methapyrilene results in increased methylation of ADAM22 intron

NCBI chr 4:26,670,984...26,925,843
Ensembl chr 4:26,671,112...26,925,843

G

ADAM metallopeptidase domain 23

increases methylation

ISO

Methapyrilene results in increased methylation of ADAM23 intron

NCBI chr 9:72,356,479...72,503,545
Ensembl chr 9:72,356,479...72,503,545

G

ADAM metallopeptidase domain 28

increases methylation

ISO

Methapyrilene results in increased methylation of ADAM28 intron

NCBI chr15:50,184,286...50,250,605
Ensembl chr15:50,127,516...50,250,526

G

ADAM metallopeptidase with thrombospondin type 1 motif, 10

increases methylation

ISO

Methapyrilene results in increased methylation of ADAMTS10 intron

NCBI chr 7:15,033,859...15,063,800
Ensembl chr 7:15,033,934...15,063,800

G

ADAM metallopeptidase with thrombospondin type 1 motif, 13

decreases methylation

ISO

Methapyrilene results in decreased methylation of ADAMTS13 intron

NCBI chr 3:30,697,354...30,736,539
Ensembl chr 3:30,697,942...30,736,540

G

ADAM metallopeptidase with thrombospondin type 1 motif, 14

increases methylation

ISO

Methapyrilene results in increased methylation of ADAMTS14 exon; Methapyrilene results in increased methylation of ADAMTS14 intron

NCBI chr20:29,685,876...29,762,685
Ensembl chr20:29,685,876...29,762,682

G

ADAM metallopeptidase with thrombospondin type 1 motif, 17

increases methylation

ISO

Methapyrilene results in increased methylation of ADAMTS17 intron

NCBI chr 1:129,856,062...130,178,430
Ensembl chr 1:129,856,074...130,176,844

G

ADAM metallopeptidase with thrombospondin type 1 motif, 18

increases methylation

ISO

Methapyrilene results in increased methylation of ADAMTS18 intron

NCBI chr19:58,596,095...58,749,239
Ensembl chr19:58,597,761...58,749,138

G

ADAM metallopeptidase with thrombospondin type 1 motif, 19

decreases methylation

ISO

Methapyrilene results in decreased methylation of ADAMTS19 intron

NCBI chr18:54,545,357...54,729,184
Ensembl chr18:54,545,357...54,729,181

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

affects methylation

ISO

Methapyrilene affects the methylation of ADAMTS2 intron

NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483

G

ADAM metallopeptidase with thrombospondin type 1 motif, 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of ADAMTS20 intron

NCBI chr 7:127,275,538...127,407,325
Ensembl chr 7:127,275,538...127,407,296

G

ADAMTS-like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ADAMTSL1 intron

NCBI chr 5:105,010,471...105,965,792
Ensembl chr 5:105,010,464...105,964,394

G

ADAMTS-like 3

increases methylation

ISO

Methapyrilene results in increased methylation of ADAMTSL3 intron

NCBI chr 1:145,698,004...146,006,195
Ensembl chr 1:145,698,004...146,006,195

G

ArfGAP with dual PH domains 1

increases methylation

ISO

Methapyrilene results in increased methylation of ADAP1 intron

NCBI chr12:20,438,091...20,489,961
Ensembl chr12:20,438,063...20,495,020

G

adenosine deaminase, RNA-specific, B1

increases methylation

ISO

Methapyrilene results in increased methylation of ADARB1 intron

NCBI chr20:11,222,171...11,350,416
Ensembl chr20:11,222,164...11,350,415

G

adenosine deaminase RNA specific B2

affects methylation

ISO

Methapyrilene affects the methylation of ADARB2 intron

NCBI chr17:66,660,586...67,211,104
Ensembl chr17:66,665,506...67,210,749

G

adenylate cyclase 1

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of ADCY1 3' UTR
Methapyrilene results in increased methylation of ADCY1 intron

NCBI chr14:86,125,119...86,234,459
Ensembl chr14:86,124,850...86,261,075

G

adenylate cyclase 10

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of ADCY10 mRNA
Methapyrilene results in increased methylation of ADCY10 gene

PMID:30467583 PMID:31555880

NCBI chr13:80,280,595...80,366,939
Ensembl chr13:80,284,295...80,366,926

G

adenylate cyclase 2

affects methylation

ISO

Methapyrilene affects the methylation of ADCY2 intron

NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645

G

adenylate cyclase 3

increases methylation

ISO

Methapyrilene results in increased methylation of ADCY3 intron

NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173

G

adenylate cyclase 5

increases methylation

ISO

Methapyrilene results in increased methylation of ADCY5 intron

NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343

G

adenylate cyclase 7

increases methylation

ISO

Methapyrilene results in increased methylation of ADCY7 intron

NCBI chr19:34,913,154...34,972,366
Ensembl chr19:34,914,322...34,936,743

G

ADCYAP receptor type I

increases methylation

ISO

Methapyrilene results in increased methylation of ADCYAP1R1 intron

NCBI chr 4:85,924,171...85,972,973
Ensembl chr 4:85,924,100...85,972,973

G

adhesion G protein-coupled receptor A2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ADGRA2 intron

NCBI chr16:71,635,814...71,674,275
Ensembl chr16:71,636,164...71,674,154

G

adhesion G protein-coupled receptor B1

increases methylation

ISO

Methapyrilene results in increased methylation of ADGRB1 intron

NCBI chr 7:108,293,681...108,365,892
Ensembl chr 7:108,293,818...108,365,870

G

adhesion G protein-coupled receptor B2

increases methylation

ISO

Methapyrilene results in increased methylation of ADGRB2 intron

NCBI chr 5:147,581,573...147,646,726
Ensembl chr 5:147,611,580...147,646,726

G

adhesion G protein-coupled receptor D1

increases methylation

ISO

Methapyrilene results in increased methylation of ADGRD1 intron

NCBI chr12:33,124,981...33,239,778
Ensembl chr12:33,125,915...33,272,509

G

adhesion G protein-coupled receptor G2

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of ADGRG2 intron
Methapyrilene results in decreased expression of ADGRG2 mRNA

PMID:30157460 PMID:30467583

NCBI chr X:38,106,067...38,231,286
Ensembl chr X:38,106,067...38,231,331

G

adhesion G protein-coupled receptor L2

decreases expression

EXP

Methapyrilene results in decreased expression of ADGRL2 mRNA

NCBI chr 2:240,356,176...240,987,246
Ensembl chr 2:240,356,177...240,855,933

G

adhesion G protein-coupled receptor V1

increases methylation
affects methylation

ISO

Methapyrilene results in increased methylation of ADGRV1 exon
Methapyrilene affects the methylation of ADGRV1 intron

NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372

G

alcohol dehydrogenase, iron containing, 1

decreases expression

EXP

Methapyrilene results in decreased expression of ADHFE1 mRNA

NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835

G

adrenomedullin

increases expression

EXP

Methapyrilene results in increased expression of ADM mRNA

NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371

G

ADP-dependent glucokinase

decreases expression

EXP

Methapyrilene results in decreased expression of ADPGK mRNA

NCBI chr 8:68,595,194...68,623,179
Ensembl chr 8:68,595,248...68,623,178

G

adrenoceptor alpha 1A

increases methylation

ISO

Methapyrilene results in increased methylation of ADRA1A intron

NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534

G

AE binding protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of AEBP2 intron

NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422

G

actin filament associated protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of AFAP1 3' UTR

NCBI chr14:78,967,961...79,081,032
Ensembl chr14:78,967,961...79,080,939

G

actin filament associated protein 1-like 2

increases methylation

ISO

Methapyrilene results in increased methylation of AFAP1L2 intron

NCBI chr 1:265,969,368...266,065,951
Ensembl chr 1:265,969,368...266,065,943

G

ALF transcription elongation factor 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of AFF2 intron

NCBI chr X:152,972,579...153,477,080
Ensembl chr X:152,972,581...153,477,080

G

ALF transcription elongation factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of AFF3 intron

NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:47,894,903...48,353,000

G

ALF transcription elongation factor 4

decreases expression

EXP

Methapyrilene results in decreased expression of AFF4 mRNA

NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,999,579...38,080,580

G

arylformamidase

decreases expression

EXP

Methapyrilene results in decreased expression of AFMID mRNA

NCBI chr10:103,544,822...103,560,408
Ensembl chr10:103,544,841...103,560,408

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of AGAP1 intron

NCBI chr 9:97,487,382...97,922,870
Ensembl chr 9:97,487,406...97,922,870

G

AGBL carboxypeptidase 4

increases methylation

ISO

Methapyrilene results in increased methylation of AGBL4 intron

NCBI chr 5:130,483,551...131,762,906

G

ArfGAP with FG repeats 2

affects methylation

ISO

Methapyrilene affects the methylation of AGFG2 intron

NCBI chr12:24,649,008...24,692,069
Ensembl chr12:24,649,038...24,685,197

G

acylglycerol kinase

increases methylation

ISO

Methapyrilene results in increased methylation of AGK intron

NCBI chr 4:70,081,550...70,160,642
Ensembl chr 4:70,081,035...70,160,709

G

argonaute RISC catalytic component 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of AGO2 intron

NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:106,918,125...106,993,980

G

1-acylglycerol-3-phosphate O-acyltransferase 3

decreases expression

EXP

Methapyrilene results in decreased expression of AGPAT3 mRNA

NCBI chr20:10,330,650...10,415,026
Ensembl chr20:10,394,465...10,410,632

G

adenosylhomocysteinase

increases expression

EXP

Methapyrilene results in increased expression of AHCY protein

NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587

G

adenosylhomocysteinase-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of AHCYL1 mRNA

NCBI chr 2:197,982,335...198,016,770
Ensembl chr 2:197,982,344...198,033,930

G

AT hook, DNA binding motif, containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of AHDC1 intron

NCBI chr 5:150,512,182...150,578,804
Ensembl chr 5:150,512,037...150,583,144

G

Abelson helper integration site 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of AHI1 intron

NCBI chr 1:17,580,859...17,711,775
Ensembl chr 1:17,582,006...17,711,774

G

AHNAK nucleoprotein

affects methylation

ISO

Methapyrilene affects the methylation of AHNAK intron

NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675

G

apoptosis inducing factor, mitochondria associated 1

decreases expression

EXP

Methapyrilene results in decreased expression of AIFM1 mRNA

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237

G

androgen-induced 1

decreases expression

EXP

Methapyrilene results in decreased expression of AIG1 mRNA

NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155

G

aryl hydrocarbon receptor-interacting protein-like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of AIPL1 intron

NCBI chr10:57,154,226...57,163,455
Ensembl chr10:57,154,226...57,163,455

G

autoimmune regulator

decreases methylation

ISO

Methapyrilene results in decreased methylation of AIRE exon

NCBI chr20:10,635,775...10,650,709
Ensembl chr20:10,635,775...10,650,709

G

adenylate kinase 3

decreases expression

EXP

Methapyrilene results in decreased expression of AK3 mRNA

NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183

G

A-kinase anchoring protein 14

increases methylation

ISO

Methapyrilene results in increased methylation of AKAP14 intron

NCBI chr X:121,261,195...121,276,376
Ensembl chr X:121,259,899...121,276,376

G

A-kinase anchoring protein 9

decreases expression

EXP

Methapyrilene results in decreased expression of AKAP9 mRNA

NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338

G

A-kinase interacting protein 1

increases expression

EXP

Methapyrilene results in increased expression of AKIP1 mRNA

NCBI chr 1:173,169,520...173,178,445
Ensembl chr 1:173,169,458...173,178,445

G

AT-hook transcription factor

affects methylation

ISO

Methapyrilene affects the methylation of AKNA exon; Methapyrilene affects the methylation of AKNA intron

NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528

G

aldo-keto reductase family 1 member B1

increases expression

EXP

Methapyrilene results in increased expression of AKR1B1 mRNA

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 1 member B15

increases expression

EXP

Methapyrilene results in increased expression of AKR1B8 mRNA

NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349

G

aldo-keto reductase family 1, member C14

decreases expression

EXP

Methapyrilene results in decreased expression of AKR1C14 mRNA

NCBI chr17:71,066,197...71,083,184
Ensembl chr17:71,066,200...71,083,157

G

aldo-keto reductase family 1, member C3

increases methylation

ISO

Methapyrilene results in increased methylation of AKR1C3 intron

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438

G

aldo-keto reductase family 1, member D1

decreases expression
decreases methylation
increases expression

EXP
ISO

Methapyrilene results in decreased expression of AKR1D1 mRNA
Methapyrilene results in decreased methylation of AKR1D1 intron
Methapyrilene results in increased expression of AKR1D1 protein

PMID:30157460 PMID:30467583

NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540

G

aldo-keto reductase family 7 member A3

increases expression

EXP

Methapyrilene results in increased expression of AKR7A3 mRNA

PMID:15120968 PMID:21813463 PMID:22484513

NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153

G

AKT serine/threonine kinase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of AKT1 intron

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

5'-aminolevulinate synthase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ALAS1 mRNA

NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642

G

albumin

decreases expression

ISO

Methapyrilene results in decreased expression of ALB mRNA

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldehyde dehydrogenase 1 family, member A1

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of ALDH1A1 mRNA
Methapyrilene results in decreased expression of ALDH1A1 mRNA

PMID:21813463 PMID:22484513 PMID:30467583

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500

G

aldehyde dehydrogenase 1 family, member A3

increases methylation

ISO

Methapyrilene results in increased methylation of ALDH1A3 exon

NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777

G

aldehyde dehydrogenase 1 family, member L1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ALDH1L1 intron

NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704

G

aldehyde dehydrogenase 1 family, member L2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ALDH1L2 intron

NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398

G

aldehyde dehydrogenase 2 family member

increases expression

EXP

Methapyrilene results in increased expression of ALDH2 protein

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219

G

aldehyde dehydrogenase 3 family, member A2

decreases expression

EXP

Methapyrilene results in decreased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648

G

aldehyde dehydrogenase 3 family, member B2

increases methylation

ISO

Methapyrilene results in increased methylation of ALDH3B2 intron

NCBI chr 1:210,679,749...210,694,187
Ensembl chr 1:210,675,302...210,694,155

G

aldehyde dehydrogenase 3 family, member B3

increases methylation

ISO

Methapyrilene results in increased methylation of ALDH3B2 intron

NCBI chr 1:210,617,090...210,629,886
Ensembl chr 1:210,622,639...210,629,879

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

EXP

Methapyrilene results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:157,162,945...157,188,673

G

aldehyde dehydrogenase 6 family, member A1

decreases expression

EXP

Methapyrilene results in decreased expression of ALDH6A1 mRNA

NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743

G

aldehyde dehydrogenase 9 family, member A1

decreases expression

EXP

Methapyrilene results in decreased expression of ALDH9A1 mRNA

NCBI chr13:82,038,679...82,055,478
Ensembl chr13:82,038,533...82,055,481

G

aldolase, fructose-bisphosphate A

increases expression

EXP

Methapyrilene results in increased expression of ALDOA mRNA

PMID:16393664 PMID:28935588

NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211

G

aldolase, fructose-bisphosphate B

decreases expression

EXP

Methapyrilene results in decreased expression of ALDOB mRNA

NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740

G

ALG11, alpha-1,2-mannosyltransferase

decreases expression

EXP

Methapyrilene results in decreased expression of ALG11 mRNA

NCBI chr16:76,642,979...76,654,052
Ensembl chr16:76,646,795...76,654,040

G

ALG13, UDP-N-acetylglucosaminyltransferase subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of ALG13 intron

NCBI chr X:112,703,015...112,764,924
Ensembl chr X:112,702,796...112,739,356

G

ALG14, UDP-N-acetylglucosaminyltransferase subunit

decreases expression

EXP

Methapyrilene results in decreased expression of ALG14 mRNA

NCBI chr 2:212,053,008...212,130,136
Ensembl chr 2:212,044,969...212,130,140

G

ALK receptor tyrosine kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of ALK intron

NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721

G

arachidonate epidermal lipoxygenase 3

increases methylation

ISO

Methapyrilene results in increased methylation of ALOXE3 intron

NCBI chr10:54,329,224...54,353,167
Ensembl chr10:54,329,043...54,353,166

G

alkaline phosphatase, biomineralization associated

decreases methylation

ISO

Methapyrilene results in decreased methylation of ALPL intron

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

ALS2 C-terminal like

decreases expression

EXP

Methapyrilene results in decreased expression of ALS2CL mRNA

NCBI chr 8:119,746,498...119,762,824
Ensembl chr 8:119,743,248...119,762,843

G

ALX homeobox 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of ALX4 intron

NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:100,067,052...100,103,624

G

Aly/REF export factor

increases expression

EXP

Methapyrilene results in increased expression of ALYREF mRNA

NCBI chr10:106,369,750...106,373,395
Ensembl chr10:106,369,750...106,373,395

G

alpha-methylacyl-CoA racemase

decreases expression

EXP

Methapyrilene results in decreased expression of AMACR mRNA

PMID:15120968 PMID:28529062

NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:61,670,475...61,685,379

G

amidohydrolase domain containing 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of AMDHD2 intron

NCBI chr10:13,692,136...13,700,632
Ensembl chr10:13,692,146...13,700,632

G

APC membrane recruitment protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of AMER1 exon

NCBI chr X:64,310,492...64,326,377
Ensembl chr X:64,300,953...64,326,332

G

APC membrane recruitment protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of AMER3 exon

NCBI chr 9:44,286,274...44,298,246
Ensembl chr 9:44,268,722...44,351,398

G

angiomotin like 2

increases methylation

ISO

Methapyrilene results in increased methylation of AMOTL2 intron

NCBI chr 8:112,182,060...112,198,032
Ensembl chr 8:112,181,863...112,198,030

G

adenosine monophosphate deaminase 3

increases expression

EXP

Methapyrilene results in increased expression of AMPD3 mRNA

NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608

G

archaelysin family metallopeptidase 2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of AMZ2 mRNA
Methapyrilene results in increased methylation of AMZ2 intron

PMID:30157460 PMID:30467583

NCBI chr10:94,901,053...94,911,629
Ensembl chr10:94,901,129...94,911,627

G

anaphase promoting complex subunit 2

increases methylation

ISO

Methapyrilene results in increased methylation of ANAPC2 intron

NCBI chr 3:28,484,590...28,496,338
Ensembl chr 3:28,484,614...28,496,337

G

angiopoietin-like 3

increases expression

EXP

Methapyrilene results in increased expression of ANGPTL3 mRNA

NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444

G

ankyrin 1

affects methylation

ISO

Methapyrilene affects the methylation of ANK1 intron

NCBI chr16:75,578,824...75,757,464
Ensembl chr16:75,578,824...75,757,464

G

ankyrin 2

increases methylation

ISO

Methapyrilene results in increased methylation of ANK2 intron

NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259

G

ankyrin-repeat and fibronectin type III domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANKFN1 intron

NCBI chr10:74,711,284...75,099,954

G

ankyrin repeat and FYVE domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of ANKFY1 intron

NCBI chr10:57,810,781...57,882,495
Ensembl chr10:57,810,781...57,882,495

G

ANKH inorganic pyrophosphate transport regulator

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of ANKH mRNA
Methapyrilene results in increased methylation of ANKH intron

PMID:30157460 PMID:30467583

NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699

G

ankyrin repeat and KH domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANKHD1 intron

NCBI chr18:28,436,296...28,534,954
Ensembl chr18:28,436,394...28,534,954

G

ankyrin repeat and LEM domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of ANKLE2 intron

NCBI chr12:52,077,863...52,110,775
Ensembl chr12:52,077,480...52,108,708

G

ankyrin repeat domain 24

increases methylation

ISO

Methapyrilene results in increased methylation of ANKRD24 intron

NCBI chr 7:8,712,720...8,731,910
Ensembl chr 7:8,712,722...8,731,910

G

ankyrin repeat domain containing 26

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANKRD26 intron

NCBI chr 4:153,342,901...153,412,321
Ensembl chr 4:153,343,578...153,412,256

G

ankyrin repeat domain 31

increases methylation

ISO

Methapyrilene results in increased methylation of ANKRD31 intron

NCBI chr 2:29,793,882...29,987,621
Ensembl chr 2:29,813,940...29,977,149

G

ankyrin repeat domain 40

increases methylation

ISO

Methapyrilene results in increased methylation of ANKRD40 intron

NCBI chr10:79,778,966...79,792,212
Ensembl chr10:56,415,260...56,416,345
Ensembl chr10:56,415,260...56,416,345

G

ankyrin repeat domain 42

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of ANKRD42 mRNA
Methapyrilene results in increased methylation of ANKRD42 intron

PMID:30157460 PMID:30467583

NCBI chr 1:156,060,516...156,103,543
Ensembl chr 1:156,060,516...156,103,517

G

ankyrin repeat domain 44

decreases expression

EXP

Methapyrilene results in decreased expression of ANKRD44 mRNA

NCBI chr 9:63,621,193...63,921,999
Ensembl chr 9:63,555,869...63,921,940

G

ankyrin repeat and sterile alpha motif domain containing 4B

decreases expression

EXP

Methapyrilene results in decreased expression of ANKS4B mRNA

NCBI chr 1:183,934,528...183,989,127
Ensembl chr 1:183,978,769...183,989,122

G

ankyrin repeat and sterile alpha motif domain containing 6

increases methylation

ISO

Methapyrilene results in increased methylation of ANKS6 intron

NCBI chr 5:66,104,770...66,146,186
Ensembl chr 5:66,104,773...66,146,186

G

ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANKZF1 intron

NCBI chr 9:84,136,862...84,143,830
Ensembl chr 9:84,136,862...84,145,091

G

anoctamin 1

affects methylation

ISO

Methapyrilene affects the methylation of ANO1 intron

NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550

G

anoctamin 2

increases methylation

ISO

Methapyrilene results in increased methylation of ANO2 intron

NCBI chr 4:160,200,471...160,541,830
Ensembl chr 4:160,182,152...160,541,821

G

anoctamin 3

increases methylation

ISO

Methapyrilene results in increased methylation of ANO3 intron

NCBI chr 3:117,690,242...118,004,695
Ensembl chr 3:117,692,103...118,004,675

G

anoctamin 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANO7 polyA tail

NCBI chr 9:101,364,915...101,392,711
Ensembl chr 9:101,364,842...101,394,173

G

acidic nuclear phosphoprotein 32 family member A

increases expression

EXP

Methapyrilene results in increased expression of ANP32A mRNA

NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922

G

acidic nuclear phosphoprotein 32 family member E

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANP32E intron

NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986

G

ANTXR cell adhesion molecule 1

increases expression

ISO

Methapyrilene results in increased expression of ANTXR1 mRNA

NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892

G

ANTXR cell adhesion molecule 2

increases methylation

ISO

Methapyrilene results in increased methylation of ANTXR2 intron

NCBI chr14:11,845,774...11,986,166
Ensembl chr14:11,845,700...11,986,168

G

annexin A2

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of ANXA2 mRNA
Methapyrilene results in increased methylation of ANXA2 intron

PMID:15120968 PMID:21813463 PMID:30157460

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A4

decreases methylation

ISO

Methapyrilene results in decreased methylation of ANXA4 intron

NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513

G

aminopeptidase O

decreases methylation
increases expression

ISO
EXP

Methapyrilene results in decreased methylation of AOPEP intron
Methapyrilene results in increased expression of AOPEP mRNA

PMID:30157460 PMID:30467583

NCBI chr17:1,817,001...2,133,008
Ensembl chr17:1,817,001...2,133,104

G

aldehyde oxidase 1

decreases expression

EXP

Methapyrilene results in decreased expression of AOX1 mRNA

NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980

G

adaptor related protein complex 1 subunit gamma 1

decreases expression

EXP

Methapyrilene results in decreased expression of AP1G1 mRNA

NCBI chr19:54,654,101...54,740,586
Ensembl chr19:54,620,807...54,740,586

G

adaptor related protein complex 1 subunit mu 1

increases methylation

ISO

Methapyrilene results in increased methylation of AP1M1 intron

NCBI chr16:17,620,910...17,636,431
Ensembl chr16:17,616,187...17,636,462

G

adaptor related protein complex 1 subunit sigma 2

increases expression

EXP

Methapyrilene results in increased expression of AP1S2 mRNA

NCBI chr X:34,204,601...34,230,819
Ensembl chr X:34,204,603...34,228,529

G

adaptor related protein complex 2 subunit alpha 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of AP2A1 intron

NCBI chr 1:104,520,789...104,550,655
Ensembl chr 1:104,520,792...104,550,655

G

amyloid beta precursor protein binding family A member 1

increases methylation

ISO

Methapyrilene results in increased methylation of APBA1 intron

NCBI chr 1:230,790,297...230,995,986
Ensembl chr 1:230,790,297...230,995,986

G

amyloid beta precursor protein binding family B member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of APBB2 intron

NCBI chr14:41,849,638...42,232,930
Ensembl chr14:41,911,785...42,232,280

G

APC regulator of WNT signaling pathway

increases methylation

ISO

Methapyrilene results in increased methylation of APC intron

NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022

G

APC down-regulated 1 like

increases methylation

ISO

Methapyrilene results in increased methylation of APCDD1L intron

NCBI chr 3:183,000,504...183,076,628
Ensembl chr 3:183,000,521...183,076,339

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

EXP

Methapyrilene results in increased expression of APEX1 mRNA

PMID:15890375 PMID:28935588

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

adipocyte plasma membrane associated protein

increases methylation

ISO

Methapyrilene results in increased methylation of APMAP exon

NCBI chr 3:159,869,451...159,897,727
Ensembl chr 3:159,869,451...159,897,726

G

apolipoprotein A1

decreases expression

ISO

Methapyrilene results in decreased expression of APOA1 mRNA

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729

G

apolipoprotein A2

increases expression

EXP

Methapyrilene results in increased expression of APOA2 mRNA

NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410

G

apolipoprotein B

decreases expression

EXP

Methapyrilene results in decreased expression of APOB mRNA

NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814

G

apolipoprotein C1

decreases expression
increases expression

EXP

Methapyrilene results in decreased expression of APOC1 mRNA
Methapyrilene results in increased expression of APOC1 mRNA

PMID:15120968 PMID:30467583

NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:88,474,663...88,478,155

G

apolipoprotein C3

decreases expression

EXP

Methapyrilene results in decreased expression of APOC3 mRNA

NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679

G

apolipoprotein D

increases methylation

ISO

Methapyrilene results in increased methylation of APOD intron

NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263

G

apolipoprotein M

increases expression

EXP

Methapyrilene results in increased expression of APOM mRNA

NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218

G

apolipoprotein O

increases methylation

ISO

Methapyrilene results in increased methylation of APOO intron

NCBI chr X:63,151,736...63,256,696
Ensembl chr X:63,151,814...63,256,690

G

amyloid beta precursor protein

increases expression

EXP

Methapyrilene results in increased expression of APP mRNA

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

aquaporin 1

increases methylation

ISO

Methapyrilene results in increased methylation of AQP1 intron

NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504

G

androgen receptor

increases methylation

ISO

Methapyrilene results in increased methylation of AR intron

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

activity-regulated cytoskeleton-associated protein

increases methylation

ISO

Methapyrilene results in increased methylation of ARC intron

NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220

G

archain 1

decreases expression

EXP

Methapyrilene results in decreased expression of ARCN1 mRNA

NCBI chr 8:53,954,401...53,979,005
Ensembl chr 8:53,954,404...53,979,005

G

ARF guanine nucleotide exchange factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of ARFGEF1 mRNA

NCBI chr 5:13,764,507...13,859,237
Ensembl chr 5:13,764,975...13,859,237

G

ARF related protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of ARFRP1 mRNA

NCBI chr 3:188,844,013...188,851,473
Ensembl chr 3:188,845,511...188,851,431

G

arginase 1

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of ARG1 protein
Methapyrilene results in decreased expression of ARG1 mRNA

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

Rho GTPase activating protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of ARHGAP1 mRNA

NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154

G

Rho GTPase activating protein 19

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGAP19 intron

NCBI chr 1:250,519,703...250,566,705
Ensembl chr 1:250,530,214...250,580,190

G

Rho GTPase activating protein 26

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGAP26 intron

NCBI chr18:30,702,602...31,489,047
Ensembl chr18:31,089,787...31,489,047

G

Rho GTPase activating protein 27

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGAP27 intron; Methapyrilene results in decreased methylation of ARHGAP27 promoter

NCBI chr10:88,780,527...88,813,275
Ensembl chr10:88,780,527...88,814,616

G

Rho GTPase activating protein 31

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGAP31 intron

NCBI chr11:75,544,176...75,657,087
Ensembl chr11:75,544,040...75,661,076

G

Rho GTPase activating protein 35

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGAP35 intron

NCBI chr 1:86,330,566...86,447,414
Ensembl chr 1:86,330,566...86,447,414

G

Rho GTPase activating protein 39

affects methylation

ISO

Methapyrilene affects the methylation of ARHGAP39 intron

NCBI chr 7:110,326,918...110,419,500
Ensembl chr 7:110,326,918...110,419,460

G

Rho GTPase activating protein 42

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGAP42 intron

NCBI chr 8:14,436,478...14,666,588
Ensembl chr 8:14,419,256...14,666,385

G

Rho GTPase activating protein 44

increases methylation

EXP
ISO

Methapyrilene results in increased methylation of ARHGAP44 gene
Methapyrilene results in increased methylation of ARHGAP44 intron

PMID:26431795 PMID:30157460

NCBI chr10:50,154,724...50,322,027
Ensembl chr10:50,154,724...50,321,897

G

Rho GTPase activating protein 45

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGAP45 3' UTR

NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890

G

Rho GDP dissociation inhibitor beta

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGDIB intron

NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068

G

Rho guanine nucleotide exchange factor 10

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGEF10 intron

NCBI chr16:81,349,429...81,440,439
Ensembl chr16:81,349,429...81,440,054

G

Rho guanine nucleotide exchange factor 11

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGEF11 exon

NCBI chr 2:175,372,269...175,493,852
Ensembl chr 2:175,372,290...175,493,852

G

Rho guanine nucleotide exchange factor 15

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGEF15 3' UTR

NCBI chr10:54,149,372...54,162,128
Ensembl chr10:54,149,372...54,162,128

G

Rho/Rac guanine nucleotide exchange factor 2

decreases expression

EXP

Methapyrilene results in decreased expression of ARHGEF2 mRNA

NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646

G

Rho guanine nucleotide exchange factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGEF3 intron

NCBI chr16:2,308,311...2,588,634
Ensembl chr16:2,308,400...2,588,819

G

Rho guanine nucleotide exchange factor 37

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGEF37 intron

NCBI chr18:57,205,621...57,271,284
Ensembl chr18:57,230,117...57,271,031

G

Rho guanine nucleotide exchange factor 4

increases methylation

ISO

Methapyrilene results in increased methylation of ARHGEF4 intron

NCBI chr 9:44,357,716...44,500,959
Ensembl chr 9:44,357,736...44,501,550

G

Rac/Cdc42 guanine nucleotide exchange factor 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARHGEF6 intron

NCBI chr X:140,182,734...140,302,812
Ensembl chr X:140,182,734...140,344,458

G

AT-rich interaction domain 1B

increases methylation
affects expression

ISO
EXP

Methapyrilene results in increased methylation of ARID1B intron
Methapyrilene affects the expression of ARID1B mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:47,973,997...48,328,793

G

AT-rich interaction domain 2

increases methylation

ISO

Methapyrilene results in increased methylation of ARID2 intron

NCBI chr 7:129,326,371...129,443,813
Ensembl chr 7:129,324,137...129,443,187

G

AT-rich interaction domain 3A

increases methylation

ISO

Methapyrilene results in increased methylation of ARID3A intron

NCBI chr 7:10,403,161...10,431,551
Ensembl chr 7:10,405,631...10,427,926

G

AT-rich interaction domain 3C

increases methylation

ISO

Methapyrilene results in increased methylation of ARID3C promoter

NCBI chr 5:61,685,511...61,692,821
Ensembl chr 5:61,685,511...61,692,821

G

ARF like GTPase 14 effector protein like

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARL14EPL intron

NCBI chr18:41,866,458...41,897,431
Ensembl chr18:41,867,524...41,897,427

G

ARF like GTPase 15

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARL15 intron

NCBI chr 2:47,171,377...47,555,666
Ensembl chr 2:47,094,900...47,555,666

G

ARL6 interacting reticulophagy regulator 1

decreases expression

EXP

Methapyrilene results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232

G

armadillo repeat containing, X-linked 1

decreases expression

EXP

Methapyrilene results in decreased expression of ARMCX1 mRNA

NCBI chr X:102,192,225...102,196,130
Ensembl chr X:102,192,015...102,199,115

G

armadillo repeat containing, X-linked 3

decreases expression

EXP

Methapyrilene results in decreased expression of ARMCX3 mRNA

NCBI chr X:102,230,464...102,234,017
Ensembl chr X:102,219,848...102,263,297

G

arrestin, beta 1

increases methylation

ISO

Methapyrilene results in increased methylation of ARRB1 intron

NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859

G

arrestin, beta 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARRB2 intron

NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487

G

arrestin domain containing 4

decreases expression

EXP

Methapyrilene results in decreased expression of ARRDC4 mRNA

NCBI chr 1:131,779,436...131,793,438
Ensembl chr 1:131,779,437...131,793,565

G

arylsulfatase B

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of ARSB mRNA
Methapyrilene results in increased methylation of ARSB intron

PMID:30157460 PMID:30467583

NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:26,736,957...26,897,611

G

arylsulfatase G

decreases methylation

ISO

Methapyrilene results in decreased methylation of ARSG intron

NCBI chr10:94,912,094...95,063,021
Ensembl chr10:94,913,152...95,042,447

G

ADP-ribosyltransferase 5

increases methylation

ISO

Methapyrilene results in increased methylation of ART5 intron

NCBI chr 1:165,885,344...165,895,306
Ensembl chr 1:165,885,280...165,895,306

G

N-acylsphingosine amidohydrolase 1

increases expression

EXP
ISO

Methapyrilene results in increased expression of ASAH1 mRNA

NCBI chr16:57,669,927...57,701,349
Ensembl chr16:57,669,750...57,718,305

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

increases methylation

ISO

Methapyrilene results in increased methylation of ASAP2 intron

NCBI chr 6:46,386,605...46,549,669
Ensembl chr 6:46,386,605...46,549,669

G

ankyrin repeat and SOCS box-containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of ASB2 intron; Methapyrilene results in increased methylation of ASB2 promoter

NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:128,239,552...128,266,321

G

ankyrin repeat and SOCS box-containing 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of ASB4 intron

NCBI chr 4:34,473,527...34,511,163
Ensembl chr 4:34,473,408...34,512,888

G

ankyrin repeat and SOCS box-containing 7

increases methylation

ISO

Methapyrilene results in increased methylation of ASB7 intron

NCBI chr 1:129,621,462...129,677,788
Ensembl chr 1:129,635,330...129,677,505

G

activating signal cointegrator 1 complex subunit 3

decreases expression

EXP

Methapyrilene results in decreased expression of ASCC3 mRNA

NCBI chr20:55,089,430...55,372,374
Ensembl chr20:55,255,503...55,372,374

G

anti-silencing function 1B histone chaperone

decreases methylation

ISO

Methapyrilene results in decreased methylation of ASF1B intron

NCBI chr19:41,085,786...41,100,352
Ensembl chr19:41,086,114...41,100,352

G

asialoglycoprotein receptor 2

increases methylation

ISO

Methapyrilene results in increased methylation of ASGR2 intron

NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263

G

ASH1 like histone lysine methyltransferase

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of ASH1L mRNA
Methapyrilene results in decreased methylation of ASH1L intron

PMID:30157460 PMID:30467583

NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847

G

ASH2 like histone lysine methyltransferase complex subunit

decreases expression

EXP

Methapyrilene results in decreased expression of ASH2L mRNA

NCBI chr16:72,943,527...72,966,791
Ensembl chr16:72,944,949...72,967,839

G

acid sensing ion channel subunit 2

increases methylation

ISO

Methapyrilene results in increased methylation of ASIC2 intron

NCBI chr10:66,368,308...67,438,237
Ensembl chr10:66,368,310...66,636,245

G

asparagine synthetase (glutamine-hydrolyzing)

decreases expression

EXP

Methapyrilene results in decreased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050

G

asparaginase

increases methylation
decreases expression

ISO

Methapyrilene results in increased methylation of ASPG gene
Methapyrilene results in decreased expression of ASPG mRNA

NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417

G

ASPSCR1 tether for SLC2A4, UBX domain containing

decreases methylation

ISO

Methapyrilene results in decreased methylation of ASPSCR1 intron

NCBI chr10:106,450,600...106,488,231
Ensembl chr10:106,450,567...106,488,579

G

argininosuccinate synthase 1

decreases expression
increases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of ASS1 mRNA
Methapyrilene results in increased expression of ASS1 protein
Methapyrilene results in increased methylation of ASS1 gene

PMID:30467583 PMID:31555880

NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627

G

astacin like metalloendopeptidase

increases methylation

ISO

Methapyrilene results in increased methylation of ASTL intron

NCBI chr 3:135,016,444...135,032,177
Ensembl chr 3:135,016,444...135,032,177

G

astrotactin 2

increases methylation

ISO

Methapyrilene results in increased methylation of ASTN2 intron

NCBI chr 5:83,772,988...84,759,439
Ensembl chr 5:83,773,633...84,759,485

G

ASXL transcriptional regulator 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ASXL2 intron

NCBI chr 6:32,090,497...32,234,487
Ensembl chr 6:32,145,607...32,227,851

G

ATCAY kinesin light chain interacting caytaxin

increases methylation

ISO

Methapyrilene results in increased methylation of ATCAY intron

NCBI chr 7:9,138,485...9,162,249
Ensembl chr 7:9,138,587...9,163,370

G

arginyltransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ATE1 mRNA

NCBI chr 1:194,391,843...194,514,284
Ensembl chr 1:194,391,843...194,511,348

G

activating transcription factor 3

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of ATF3 mRNA
Methapyrilene results in increased methylation of ATF3 intron

PMID:15890375 PMID:22484513 PMID:30157460

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

activating transcription factor 4

increases expression

EXP

Methapyrilene results in increased expression of ATF4 mRNA

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

activating transcription factor 6

decreases expression

EXP

Methapyrilene results in decreased expression of ATF6 mRNA

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033

G

autophagy related 4C, cysteine peptidase

decreases expression

EXP

Methapyrilene results in decreased expression of ATG4C mRNA

NCBI chr 5:118,977,594...119,050,894
Ensembl chr 5:118,982,918...119,052,695

G

atonal bHLH transcription factor 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of ATOH8 intron

NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379

G

atos homolog A

increases expression

EXP

Methapyrilene results in increased expression of ATOSA mRNA

NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091

G

ATPase phospholipid transporting 10A (putative)

increases methylation

ISO

Methapyrilene results in increased methylation of ATP10A intron

NCBI chr 1:118,692,456...118,866,117
Ensembl chr 1:118,692,478...118,866,114

G

ATPase phospholipid transporting 10B

increases methylation

ISO

Methapyrilene results in increased methylation of ATP10B intron

NCBI chr10:27,996,729...28,252,801
Ensembl chr10:27,910,295...28,251,450

G

ATPase phospholipid transporting 11A

affects methylation
decreases expression

ISO
EXP

Methapyrilene affects the methylation of ATP11A intron
Methapyrilene results in decreased expression of ATP11A mRNA

PMID:30157460 PMID:30467583

NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767

G

ATPase phospholipid transporting 11C

increases methylation

ISO

Methapyrilene results in increased methylation of ATP11C intron

NCBI chr X:143,600,763...143,788,407
Ensembl chr X:143,600,767...143,788,432

G

ATPase cation transporting 13A2

increases methylation

ISO

Methapyrilene results in increased methylation of ATP13A2 intron

NCBI chr 5:158,575,727...158,595,157
Ensembl chr 5:158,575,749...158,595,156

G

ATPase Na+/K+ transporting subunit alpha 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ATP1A2 exon

NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

increases methylation

ISO

Methapyrilene results in increased methylation of ATP2A3 polyA tail

NCBI chr10:58,079,710...58,111,279
Ensembl chr10:58,079,852...58,111,278

G

ATPase plasma membrane Ca2+ transporting 2

increases methylation

ISO

Methapyrilene results in increased methylation of ATP2B2 intron

NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:148,450,207...148,696,239

G

ATPase plasma membrane Ca2+ transporting 3

increases methylation

ISO

Methapyrilene results in increased methylation of ATP2B3 intron

NCBI chr X:156,367,582...156,464,085
Ensembl chr X:156,367,852...156,438,153

G

ATP synthase F1 subunit beta

decreases expression
multiple interactions
increases expression

EXP

Methapyrilene results in decreased expression of ATP5F1B mRNA
[Diethylnitrosamine co-treated with Methapyrilene] results in decreased expression of ATP5F1B protein
Methapyrilene results in increased expression of ATP5F1B protein

PMID:28903497 PMID:30467583

NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462

G

ATP synthase peripheral stalk subunit d

increases methylation

ISO

Methapyrilene results in increased methylation of ATP5PD intron

NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954

G

ATP synthase peripheral stalk subunit OSCP

decreases methylation

ISO

Methapyrilene results in decreased methylation of ATP5PO intron

NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520

G

ATPase H+ transporting V0 subunit a4

decreases methylation

ISO

Methapyrilene results in decreased methylation of ATP6V0A4 intron

NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:67,727,145...67,809,092

G

ATPase H+ transporting V0 subunit D1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ATP6V0D1 intron

NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395

G

ATPase H+ transporting V0 subunit D2

increases methylation

ISO

Methapyrilene results in increased methylation of ATP6V0D2 intron

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245

G

ATPase H+ transporting V1 subunit B1

increases methylation

ISO

Methapyrilene results in increased methylation of ATP6V1B1 intron

NCBI chr 4:117,781,444...117,800,103
Ensembl chr 4:117,781,444...117,800,103

G

ATPase H+ transporting V1 subunit B2

increases expression

EXP

Methapyrilene results in increased expression of ATP6V1B2 mRNA

NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839

G

ATPase copper transporting alpha

affects methylation

ISO

Methapyrilene affects the methylation of ATP7A intron

NCBI chr X:75,159,635...75,267,094
Ensembl chr X:75,159,782...75,267,093

G

ATPase copper transporting beta

increases methylation

ISO

Methapyrilene results in increased methylation of ATP7B intron

NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801

G

ATPase phospholipid transporting 8A2

increases methylation

ISO

Methapyrilene results in increased methylation of ATP8A2 intron

NCBI chr15:37,993,507...38,526,408
Ensembl chr15:38,002,305...38,526,212

G

ATPase phospholipid transporting 8B1

increases expression

EXP

Methapyrilene results in increased expression of ATP8B1 mRNA

NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027

G

ATPase phospholipid transporting 8B3

increases methylation

ISO

Methapyrilene results in increased methylation of ATP8B3 intron

NCBI chr 7:9,823,496...9,846,137
Ensembl chr 7:9,826,275...9,846,195

G

ATPase, class I, type 8B, member 5

increases expression

ISO

Methapyrilene results in increased expression of ATP8B5P mRNA

NCBI chr 5:62,302,213...62,415,843
Ensembl chr 5:62,302,275...62,415,834

G

attractin like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ATRNL1 intron

NCBI chr 1:266,676,051...267,216,847
Ensembl chr 1:266,675,852...267,216,842

G

ataxin 7-like 2

increases methylation

ISO

Methapyrilene results in increased methylation of ATXN7L2 exon

NCBI chr 2:198,527,066...198,535,899
Ensembl chr 2:198,527,066...198,534,062

G

aurora kinase A and ninein interacting protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of AUNIP intron

NCBI chr 5:152,006,021...152,018,614
Ensembl chr 5:152,006,042...152,020,190

G

activator of transcription and developmental regulator AUTS2

affects methylation

ISO

Methapyrilene affects the methylation of AUTS2 intron

NCBI chr12:29,739,138...30,830,386
Ensembl chr12:29,740,523...30,830,386

G

advillin

decreases methylation

ISO

Methapyrilene results in decreased methylation of AVIL intron

NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436

G

AVL9 cell migration associated

increases methylation

ISO

Methapyrilene results in increased methylation of AVL9 intron

NCBI chr 4:87,291,062...87,338,537
Ensembl chr 4:87,291,798...87,331,916

G

Axl receptor tyrosine kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of AXL exon

NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009

G

antizyme inhibitor 1

increases expression

EXP

Methapyrilene results in increased expression of AZIN1 mRNA

PMID:16393664 PMID:30467583

NCBI chr 7:71,539,711...71,566,515
Ensembl chr 7:71,539,711...71,566,515

G

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

decreases expression

EXP

Methapyrilene results in decreased expression of B3GALNT1 mRNA

NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:156,156,265...156,188,404

G

Beta-1,3-galactosyltransferase 5

increases methylation

ISO

Methapyrilene results in increased methylation of B3GALT5 exon; Methapyrilene results in increased methylation of B3GALT5 intron

NCBI chr11:49,053,959...49,100,398
Ensembl chr11:49,006,560...49,101,283

G

beta-1,3-glucuronyltransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of B3GAT1 intron

NCBI chr 8:33,362,791...33,390,446
Ensembl chr 8:33,363,048...33,390,443

G

beta-1,3-glucuronyltransferase 2

increases methylation

ISO

Methapyrilene results in increased methylation of B3GAT2 intron

NCBI chr 9:33,663,482...33,746,466
Ensembl chr 9:33,663,482...33,746,466

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of QTGAL intron

NCBI chr10:107,363,036...107,431,988
Ensembl chr10:107,371,442...107,431,908

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of B4GALNT1 mRNA

NCBI chr 7:64,873,909...64,881,512
Ensembl chr 7:64,874,022...64,881,516

G

beta-1,4-N-acetyl-galactosaminyl transferase 3

affects methylation

ISO

Methapyrilene affects the methylation of B4GALNT3 intron

NCBI chr 4:155,081,261...155,181,255
Ensembl chr 4:155,081,261...155,181,244

G

beta-1,4-N-acetyl-galactosaminyl transferase 4

increases methylation

ISO

Methapyrilene results in increased methylation of B4GALNT4 intron

NCBI chr 1:205,600,989...205,611,889
Ensembl chr 1:205,600,989...205,611,889

G

beta-1,4-galactosyltransferase 1

affects methylation

ISO

Methapyrilene affects the methylation of B4GALT1 intron

NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445

G

beta-1,4-galactosyltransferase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of B4GALT2 intron

NCBI chr 5:136,697,981...136,707,783
Ensembl chr 5:136,697,981...136,710,422

G

bile acid CoA:amino acid N-acyltransferase

decreases expression

EXP

Methapyrilene results in decreased expression of BAAT mRNA

PMID:28529062 PMID:30467583

NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181

G

beta-secretase 2

affects methylation

ISO

Methapyrilene affects the methylation of BACE2 intron

NCBI chr11:50,176,852...50,258,948
Ensembl chr11:50,176,621...50,259,008

G

BAG cochaperone 1

increases expression

EXP

Methapyrilene results in increased expression of BAG1 mRNA

NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161

G

BAG cochaperone 6

increases methylation

ISO

Methapyrilene results in increased methylation of BAG6 exon

NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,680,607...3,693,329

G

BMP and activin membrane-bound inhibitor

increases expression

EXP

Methapyrilene results in increased expression of BAMBI mRNA

NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247

G

BCL2 associated X, apoptosis regulator

increases expression

EXP

Methapyrilene results in increased expression of BAX mRNA

PMID:15890375 PMID:17450226

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

gamma-butyrobetaine hydroxylase 1

decreases expression

EXP

Methapyrilene results in decreased expression of BBOX1 mRNA

NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064

G

Bardet-Biedl syndrome 2

decreases expression

EXP

Methapyrilene results in decreased expression of BBS2 mRNA

NCBI chr19:10,915,566...10,950,911
Ensembl chr19:10,915,476...10,950,921

G

Bardet-Biedl syndrome 5

decreases expression

EXP

Methapyrilene results in decreased expression of BBS5 mRNA

NCBI chr 3:74,818,104...74,839,658
Ensembl chr 3:74,818,473...74,857,023

G

BBX high mobility group box domain containing

increases methylation

ISO

Methapyrilene results in increased methylation of BBX intron

NCBI chr11:63,850,034...64,097,700
Ensembl chr11:63,850,018...64,093,265

G

B-cell receptor-associated protein 31

decreases methylation

ISO

Methapyrilene results in decreased methylation of BCAP31 intron

NCBI chr X:156,548,911...156,581,002
Ensembl chr X:156,548,911...156,579,371

G

BCAR1 scaffold protein, Cas family member

decreases methylation

ISO

Methapyrilene results in decreased methylation of BCAR1 intron

NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190

G

BCAS3, microtubule associated cell migration factor

increases methylation

ISO

Methapyrilene results in increased methylation of BCAS3 intron

NCBI chr10:70,711,084...71,170,492
Ensembl chr10:70,711,525...71,170,803

G

branched chain amino acid transaminase 1

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of BCAT1 mRNA
Methapyrilene results in increased methylation of BCAT1 intron

PMID:23558518 PMID:30157460

NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288

G

branched chain keto acid dehydrogenase E1 subunit alpha

decreases expression
affects expression

EXP

Methapyrilene results in decreased expression of BCKDHA mRNA
Methapyrilene affects the expression of BCKDHA protein

PMID:16393664 PMID:30467583

NCBI chr 1:90,266,731...90,295,521
Ensembl chr 1:90,261,629...90,295,749

G

branched chain keto acid dehydrogenase E1 subunit beta

increases methylation

ISO

Methapyrilene results in increased methylation of BCKDHB intron

NCBI chr 8:93,725,277...93,907,799
Ensembl chr 8:93,725,275...93,907,798

G

branched chain ketoacid dehydrogenase kinase

decreases expression

EXP

Methapyrilene results in decreased expression of BCKDK mRNA

NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453

G

BCL11 transcription factor B

increases methylation

ISO

Methapyrilene results in increased methylation of BCL11B intron

NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:132,598,968...132,691,301

G

Bcl2-like 14

increases methylation

ISO

Methapyrilene results in increased methylation of BCL2L14 intron

NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079

G

Bcl2-like 2

decreases expression

EXP

Methapyrilene results in decreased expression of BCL2L2 mRNA

NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379

G

BCL6, transcription repressor

decreases expression

EXP

Methapyrilene results in decreased expression of BCL6 mRNA

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047

G

BAF chromatin remodeling complex subunit BCL7A

decreases methylation

ISO

Methapyrilene results in decreased methylation of BCL7A intron

NCBI chr12:38,872,851...38,904,770
Ensembl chr12:38,872,851...38,904,770

G

BAF chromatin remodeling complex subunit BCL7C

increases methylation

ISO

Methapyrilene results in increased methylation of BCL7C polyA tail

NCBI chr 1:191,703,432...191,754,751
Ensembl chr 1:191,691,089...191,754,641

G

BCL9, transcription coactivator

increases methylation

ISO

Methapyrilene results in increased methylation of BCL9 intron

NCBI chr 2:187,449,425...187,475,241
Ensembl chr 2:187,449,425...187,475,241

G

3-hydroxybutyrate dehydrogenase 1

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of BDH1 mRNA
Methapyrilene results in increased methylation of BDH1 intron

PMID:16393664 PMID:30157460

NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636

G

brain-enriched guanylate kinase-associated

decreases methylation

ISO

Methapyrilene results in decreased methylation of BEGAIN intron

NCBI chr 6:133,708,010...133,744,264
Ensembl chr 6:133,708,007...133,744,526

G

BEN domain containing 5

increases methylation

ISO

Methapyrilene results in increased methylation of BEND5 intron

NCBI chr 5:131,519,214...131,565,228
Ensembl chr 5:131,519,214...131,762,906

G

Bet1 golgi vesicular membrane trafficking protein

decreases expression

EXP

Methapyrilene results in decreased expression of BET1 mRNA

NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164

G

brain expressed X-linked 3

increases expression

EXP

Methapyrilene results in increased expression of BEX3 mRNA

NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906

G

beaded filament structural protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of BFSP1 intron

NCBI chr 3:151,648,588...151,706,153
Ensembl chr 3:151,648,588...151,682,837

G

biglycan

increases methylation

ISO

Methapyrilene results in increased methylation of BGN intron

NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799

G

basic helix-loop-helix family, member a15

decreases expression

EXP

Methapyrilene results in decreased expression of BHLHA15 mRNA

NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515

G

betaine-homocysteine S-methyltransferase

decreases expression

EXP

Methapyrilene results in decreased expression of BHMT mRNA

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715

G

betaine-homocysteine S-methyltransferase 2

decreases expression

EXP

Methapyrilene results in decreased expression of BHMT2 mRNA

NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326

G

BICD family like cargo adaptor 1

increases methylation

ISO

Methapyrilene results in increased methylation of BICDL1 intron

NCBI chr12:46,537,525...46,626,876
Ensembl chr12:46,538,396...46,628,866

G

BICRA like chromatin remodeling complex associated protein

increases methylation

ISO

Methapyrilene results in increased methylation of BICRAL intron

NCBI chr 9:21,597,886...21,682,985
Ensembl chr 9:21,597,855...21,682,983

G

bridging integrator 3

affects methylation

ISO

Methapyrilene affects the methylation of BIN3 intron

NCBI chr15:51,583,474...51,622,329
Ensembl chr15:51,583,481...51,622,329

G

BLACAT1 overlapping LEMD1 locus

decreases methylation

ISO

Methapyrilene results in decreased methylation of BLACAT1 intron

NCBI chr13:46,189,091...46,202,506
Ensembl chr13:46,197,208...46,197,306

G

BLK proto-oncogene, Src family tyrosine kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of BLK exon

NCBI chr15:41,802,701...41,841,004
Ensembl chr15:41,802,994...41,840,982

G

biogenesis of lysosomal organelles complex 1 subunit 6

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of BLOC1S6 polyA tail
Methapyrilene results in decreased expression of BLOC1S6 mRNA

PMID:30157460 PMID:30467583

NCBI chr 3:130,269,979...130,280,109
Ensembl chr 3:130,268,442...130,281,360

G

bridge-like lipid transfer protein family member 3A

increases methylation

ISO

Methapyrilene results in increased methylation of BLTP3A promoter

NCBI chr20:5,912,033...5,956,404
Ensembl chr20:5,912,106...5,956,403

G

bridge-like lipid transfer protein family member 3B

decreases expression

EXP

Methapyrilene results in decreased expression of BLTP3B mRNA

NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083

G

bone morphogenetic protein receptor type 1A

decreases methylation

ISO

Methapyrilene results in decreased methylation of BMPR1A 3' UTR

NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861

G

bone morphogenetic protein receptor type 2

increases methylation

ISO

Methapyrilene results in increased methylation of BMPR2 intron

NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350

G

BOC cell adhesion associated, oncogene regulated

increases methylation

ISO

Methapyrilene results in increased methylation of BOC exon

NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004

G

BCL2 family apoptosis regulator BOK

affects methylation

ISO

Methapyrilene affects the methylation of BOK 3' UTR

NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833

G

biphenyl hydrolase like

decreases expression

EXP

Methapyrilene results in decreased expression of BPHL mRNA

NCBI chr17:31,006,283...31,042,631
Ensembl chr17:31,004,972...31,042,632

G

3'(2'), 5'-bisphosphate nucleotidase 2

decreases expression

EXP

Methapyrilene results in decreased expression of BPNT2 mRNA

NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126

G

BRCA1/BRCA2-containing complex subunit 3

decreases expression

EXP

Methapyrilene results in decreased expression of BRCC3 mRNA

NCBI chr 9:2,073,927...2,076,469
Ensembl chr 9:2,073,184...2,084,185

G

bromodomain containing 2

increases expression

EXP

Methapyrilene results in increased expression of BRD2 mRNA

NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290

G

bromodomain containing 8

increases methylation
decreases expression

EXP

Methapyrilene results in increased methylation of BRD8 gene
Methapyrilene results in decreased expression of BRD8 mRNA

PMID:26431795 PMID:30467583

NCBI chr18:26,455,824...26,504,106
Ensembl chr18:26,455,512...26,504,006

G

BRF1 general transcription factor IIIB subunit

increases methylation

ISO

Methapyrilene results in increased methylation of BRF1 intron

NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386

G

brain protein I3

increases methylation

ISO

Methapyrilene results in increased methylation of BRI3 intron

NCBI chr12:15,454,673...15,478,319
Ensembl chr12:15,454,673...15,478,319

G

BMP/retinoic acid inducible neural specific 1

increases methylation

ISO

Methapyrilene results in increased methylation of BRINP1 intron

NCBI chr 5:87,363,621...87,565,580
Ensembl chr 5:87,364,050...87,508,256

G

BMP/retinoic acid inducible neural specific 2

increases methylation

ISO

Methapyrilene results in increased methylation of BRINP2 exon; Methapyrilene results in increased methylation of BRINP2 intron

NCBI chr13:72,964,498...73,065,312
Ensembl chr13:72,964,502...73,065,294

G

BMP/retinoic acid inducible neural specific 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of BRINP3 intron

NCBI chr13:60,964,127...61,397,044
Ensembl chr13:60,966,100...61,397,039

G

BR serine/threonine kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of BRSK2 intron

NCBI chr 1:206,465,040...206,518,156
Ensembl chr 1:206,465,040...206,518,156

G

bassoon (presynaptic cytomatrix protein)

increases methylation

ISO

Methapyrilene results in increased methylation of BSN exon

NCBI chr 8:117,663,447...117,754,412
Ensembl chr 8:117,670,334...117,754,412

G

BTB domain containing 3

increases methylation

ISO

Methapyrilene results in increased methylation of BTBD3 promoter

NCBI chr 3:146,044,053...146,074,189
Ensembl chr 3:146,044,096...146,074,635

G

BTG anti-proliferation factor 2

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of BTG2 mRNA
Methapyrilene results in decreased expression of BTG2 mRNA

PMID:15890375 PMID:21813463 PMID:28935588 PMID:30467583

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690

G

BTG anti-proliferation factor 4

increases methylation

ISO

Methapyrilene results in increased methylation of BTG4 intron

NCBI chr 8:60,307,090...60,322,167
Ensembl chr 8:60,317,121...60,322,167

G

Bruton tyrosine kinase

increases methylation

ISO

Methapyrilene results in increased methylation of BTK intron

NCBI chr X:102,016,070...102,055,448
Ensembl chr X:102,016,074...102,055,143

G

BUD23, rRNA methyltransferase and ribosome maturation factor

increases methylation

ISO

Methapyrilene results in increased methylation of BUD23 intron

NCBI chr12:27,266,093...27,277,300
Ensembl chr12:27,265,521...27,277,297

G

similar to human chromosome 16 open reading frame 89

increases methylation

ISO

Methapyrilene results in increased methylation of C16ORF89 5' UTR

NCBI chr10:10,856,320...10,877,515
Ensembl chr10:10,868,419...10,877,515

G

similar to human chromosome 13 open reading frame 42

increases methylation

ISO

Methapyrilene results in increased methylation of C13ORF42 intron

NCBI chr15:40,852,879...40,877,320
Ensembl chr15:40,854,229...40,876,536

G

similar to human chromosome 19 open reading frame 44

decreases methylation

ISO

Methapyrilene results in decreased methylation of C19ORF44 intron

NCBI chr16:17,414,041...17,430,108
Ensembl chr16:17,414,045...17,430,183

G

similar to human chromosome 16 open reading frame 46

increases methylation

ISO

Methapyrilene results in increased methylation of C16ORF46 intron

NCBI chr19:61,931,114...61,941,517
Ensembl chr19:61,931,116...61,941,517

G

similar to human chromosome 16 open reading frame 74

increases methylation

ISO

Methapyrilene results in increased methylation of C16ORF74 polyA tail

NCBI chr19:65,568,997...65,594,994
Ensembl chr19:65,568,997...65,595,460

G

C1GALT1-specific chaperone 1

increases methylation

ISO

Methapyrilene results in increased methylation of C1GALT1C1 intron

NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422

G

similar to human chromosome 11 open reading frame 98

decreases methylation

ISO

Methapyrilene results in decreased methylation of C11ORF98 polyA tail

NCBI chr 1:215,211,658...215,213,687
Ensembl chr 1:215,211,688...215,213,687

G

similar to human chromosome 19 open reading frame 18

increases methylation

ISO

Methapyrilene results in increased methylation of C19ORF18 intron

NCBI chr 1:82,094,513...82,122,109
Ensembl chr 1:82,098,305...82,122,119

G

C1q and TNF related 2

increases methylation

ISO

Methapyrilene results in increased methylation of C1QTNF2 intron

NCBI chr10:28,443,326...28,460,400
Ensembl chr10:28,443,425...28,460,395

G

C1q and TNF related 4

increases methylation

ISO

Methapyrilene results in increased methylation of C1QTNF4 promoter

NCBI chr 3:97,310,220...97,328,818
Ensembl chr 3:97,327,670...97,342,587

G

complement C2

decreases methylation

ISO

Methapyrilene results in decreased methylation of C2 intron

NCBI chr20:3,944,722...3,975,006
Ensembl chr20:3,955,776...3,981,740

G

similar to human chromosome 3 open reading frame 80

decreases methylation

ISO

Methapyrilene results in decreased methylation of C3ORF80 promoter

NCBI chr 2:155,435,287...155,438,099
Ensembl chr 2:155,434,073...155,437,507

G

complement component 4 binding protein, alpha

increases expression

EXP

Methapyrilene results in increased expression of C4BPA mRNA

NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471

G

complement component 4 binding protein, beta

increases expression

EXP

Methapyrilene results in increased expression of C4BPB mRNA

NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793

G

similar to human chromosome 3 open reading frame 20

increases methylation

ISO

Methapyrilene results in increased methylation of C3ORF20 intron; Methapyrilene results in increased methylation of C3ORF20 polyA tail

NCBI chr 4:125,976,326...126,027,796
Ensembl chr 4:125,980,430...126,027,791

G

complement C5a receptor 1

increases methylation

ISO

Methapyrilene results in increased methylation of C5AR1 promoter

NCBI chr 1:86,077,309...86,088,001

G

similar to human chromosome 8 open reading frame 34

increases methylation

ISO

Methapyrilene results in increased methylation of C8ORF34 intron

NCBI chr 5:12,021,000...12,560,212
Ensembl chr 5:12,021,007...12,559,772

G

complement C6

increases expression

EXP

Methapyrilene results in increased expression of C6 mRNA

NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120

G

complement C8 beta chain

increases expression

EXP

Methapyrilene results in increased expression of C8B mRNA

NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516

G

complement C8 gamma chain

increases expression

EXP

Methapyrilene results in increased expression of C8G mRNA

NCBI chr 3:28,718,648...28,720,232

G

similar to human chromosome 15 open reading frame 39

increases methylation

ISO

Methapyrilene results in increased methylation of C15ORF39 intron

NCBI chr 8:66,542,269...66,551,835
Ensembl chr 8:66,542,269...66,554,782

G

complement C9

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of C9 mRNA
Methapyrilene results in increased methylation of C9 intron

PMID:30157460 PMID:30467583

NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752

G

similar to human chromosome 6 open reading frame 132

increases methylation

ISO

Methapyrilene results in increased methylation of C6ORF132 intron

NCBI chr 9:21,022,482...21,058,942
Ensembl chr 9:21,023,092...21,059,125

G

carbonic anhydrase 3

decreases expression

EXP

Methapyrilene results in decreased expression of CAR3 mRNA

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524

G

carbonic anhydrase 5A

decreases methylation

ISO

Methapyrilene results in decreased methylation of CA5A intron

NCBI chr19:66,881,678...66,911,486
Ensembl chr19:66,881,693...66,911,486

G

calcium binding protein 39

decreases methylation

ISO

Methapyrilene results in decreased methylation of CAB39 intron

NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542

G

calcium binding protein 39-like

increases methylation

ISO

Methapyrilene results in increased methylation of CAB39L intron

NCBI chr15:37,782,778...37,885,191
Ensembl chr15:37,782,870...37,919,742

G

calcium binding protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of CABP1 intron

NCBI chr12:47,045,914...47,109,614
Ensembl chr12:47,085,292...47,109,611

G

cache domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of CACHD1 promoter

NCBI chr 5:120,527,224...120,752,685
Ensembl chr 5:120,526,770...120,772,877

G

calcium voltage-gated channel subunit alpha1 C

increases methylation
affects methylation

ISO

Methapyrilene results in increased methylation of CACNA1C exon
Methapyrilene affects the methylation of CACNA1C intron

NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762

G

calcium voltage-gated channel subunit alpha1 D

increases methylation

ISO

Methapyrilene results in increased methylation of CACNA1D intron

NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692

G

calcium voltage-gated channel subunit alpha1 G

increases methylation

ISO

Methapyrilene results in increased methylation of CACNA1G intron

NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634

G

calcium voltage-gated channel subunit alpha1 H

increases methylation

ISO

Methapyrilene results in increased methylation of CACNA1H intron

NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771

G

calcium voltage-gated channel subunit alpha1 I

affects methylation

ISO

Methapyrilene affects the methylation of CACNA1I intron

NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:113,716,266...113,827,670

G

calcium voltage-gated channel subunit alpha1 S

increases methylation

ISO

Methapyrilene results in increased methylation of CACNA1S intron

NCBI chr13:50,045,668...50,115,903
Ensembl chr13:50,045,668...50,115,903

G

calcium voltage-gated channel auxiliary subunit alpha2delta 2

increases methylation

ISO

Methapyrilene results in increased methylation of CACNA2D2 intron

NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:116,950,907...117,081,759

G

calcium voltage-gated channel auxiliary subunit alpha2delta 3

increases methylation

ISO

Methapyrilene results in increased methylation of CACNA2D3 intron

NCBI chr16:4,105,048...4,919,037
Ensembl chr16:4,105,048...4,919,098

G

calcium voltage-gated channel auxiliary subunit alpha2delta 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of CACNA2D4 intron

NCBI chr 4:154,080,877...154,197,369
Ensembl chr 4:154,080,877...154,193,778

G

calcium voltage-gated channel auxiliary subunit gamma 2

affects methylation

ISO

Methapyrilene affects the methylation of CACNG2 intron

NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:111,455,006...111,577,757

G

calcium voltage-gated channel auxiliary subunit gamma 6

increases methylation

ISO

Methapyrilene results in increased methylation of CACNG6 intron

NCBI chr 1:74,648,342...74,663,351
Ensembl chr 1:74,648,063...74,662,753

G

CDK2-associated, cullin domain 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CACUL1 intron

NCBI chr 1:269,652,356...269,712,265
Ensembl chr 1:269,652,356...269,712,112

G

cell adhesion molecule 2

increases methylation

ISO

Methapyrilene results in increased methylation of CADM2 intron

NCBI chr11:17,994,856...18,971,895
Ensembl chr11:17,994,856...18,971,448

G

caldesmon 1

decreases expression

EXP

Methapyrilene results in decreased expression of CALD1 mRNA

NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085

G

calneuron 1

affects methylation

ISO

Methapyrilene affects the methylation of CALN1 intron

NCBI chr12:31,447,964...31,939,847

G

calcium/calmodulin-dependent protein kinase ID

increases methylation

ISO

Methapyrilene results in increased methylation of CAMK1D intron

NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012

G

calcium/calmodulin-dependent protein kinase II alpha

increases methylation

ISO

Methapyrilene results in increased methylation of CAMK2A intron

NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504

G

calcium/calmodulin-dependent protein kinase II beta

increases methylation

ISO

Methapyrilene results in increased methylation of CAMK2B intron

NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

increases expression

EXP

Methapyrilene results in increased expression of CAMK2N1 mRNA

NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058

G

calcium/calmodulin-dependent protein kinase IV

decreases methylation

ISO

Methapyrilene results in decreased methylation of CAMK4 intron

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193

G

calcium/calmodulin-dependent protein kinase kinase 1

increases methylation

ISO

Methapyrilene results in increased methylation of CAMKK1 3' UTR

NCBI chr10:58,135,872...58,159,023
Ensembl chr10:58,135,915...58,159,010

G

CaM kinase-like vesicle-associated

increases methylation

ISO

Methapyrilene results in increased methylation of CAMKV exon

NCBI chr 8:117,505,439...117,519,785
Ensembl chr 8:117,505,408...117,519,797

G

calmodulin binding transcription activator 1

increases methylation

ISO

Methapyrilene results in increased methylation of CAMTA1 intron

NCBI chr 5:166,791,639...167,639,502
Ensembl chr 5:166,793,101...167,639,733

G

cyclase associated actin cytoskeleton regulatory protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of CAP1 intron

NCBI chr 5:140,427,265...140,507,678
Ensembl chr 5:140,427,269...140,453,470

G

capping actin protein, gelsolin like

decreases methylation

ISO

Methapyrilene results in decreased methylation of CAPG intron

NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672

G

calpain 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CAPN2 intron

NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625

G

calpain 8

increases methylation

ISO

Methapyrilene results in increased methylation of CAPN8 exon

NCBI chr13:96,783,640...96,847,825
Ensembl chr13:96,783,667...96,847,820

G

calpain 9

increases methylation

ISO

Methapyrilene results in increased methylation of CAPN9 exon

NCBI chr19:69,446,847...69,483,810
Ensembl chr19:69,446,847...69,483,810

G

cell cycle associated protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of CAPRIN1 mRNA

NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562

G

capping actin protein of muscle Z-line subunit beta

increases methylation

ISO

Methapyrilene results in increased methylation of CAPZB intron

NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619

G

caspase recruitment domain family, member 11

increases methylation

ISO

Methapyrilene results in increased methylation of CARD11 intron

NCBI chr12:18,735,088...18,872,045
Ensembl chr12:18,735,088...18,872,045

G

coactivator-associated arginine methyltransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of CARM1 intron

NCBI chr 8:28,373,370...28,418,056
Ensembl chr 8:28,373,362...28,418,056

G

cysteinyl-tRNA synthetase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CARS1 intron

NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407

G

cysteinyl-tRNA synthetase 2, mitochondrial

decreases methylation

ISO

Methapyrilene results in decreased methylation of CARS2 intron

NCBI chr16:84,649,617...84,689,254
Ensembl chr16:84,645,627...84,690,192

G

calcium/calmodulin dependent serine protein kinase

affects methylation

ISO

Methapyrilene affects the methylation of CASK intron

NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948

G

caspase 12

increases expression

EXP

Methapyrilene results in increased expression of CASP12 mRNA

NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442

G

caspase 3

increases activity
increases cleavage
increases expression

EXP

Methapyrilene results in increased activity of CASP3 protein
Methapyrilene results in increased cleavage of CASP3 protein
Methapyrilene results in increased expression of CASP3 mRNA

PMID:19523481 PMID:26558467 PMID:30467583

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 4

increases expression

EXP

Methapyrilene results in increased expression of CASP4 mRNA

NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727

G

caspase 9

increases expression

EXP

Methapyrilene results in increased expression of CASP9 mRNA

Ensembl chr 5:159,391,188...159,409,648

G

Cas scaffold protein family member 4

increases methylation

ISO

Methapyrilene results in increased methylation of CASS4 intron

NCBI chr 3:181,580,954...181,620,945
Ensembl chr 3:181,581,902...181,620,945

G

calpastatin

decreases expression

EXP

Methapyrilene results in decreased expression of CAST mRNA

NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:5,707,640...5,817,180

G

castor zinc finger 1

increases methylation

ISO

Methapyrilene results in increased methylation of CASZ1 intron

NCBI chr 5:164,527,083...164,677,037
Ensembl chr 5:164,527,112...164,677,014

G

catalase

decreases expression

EXP

Methapyrilene results in decreased expression of CAT mRNA

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cation channel sperm associated auxiliary subunit gamma

decreases methylation

ISO

Methapyrilene results in decreased methylation of CATSPERG exon

NCBI chr 1:93,616,209...93,646,970
Ensembl chr 1:93,616,209...93,661,618

G

caveolae associated protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CAVIN1 intron

NCBI chr10:86,384,401...86,398,240
Ensembl chr10:86,384,401...86,396,383

G

CBFA2/RUNX1 partner transcriptional co-repressor 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CBFA2T2 intron

NCBI chr 3:163,397,160...163,503,409
Ensembl chr 3:163,397,185...163,503,407

G

CBFA2/RUNX1 partner transcriptional co-repressor 3

increases methylation

ISO

Methapyrilene results in increased methylation of CBFA2T3 intron

NCBI chr19:67,584,319...67,658,533
Ensembl chr19:67,589,258...67,658,136

G

Cbl proto-oncogene B

decreases expression

EXP

Methapyrilene results in decreased expression of CBLB mRNA

NCBI chr11:62,058,829...62,225,904
Ensembl chr11:62,061,653...62,225,778

G

Cbl proto-oncogene C

decreases methylation

ISO

Methapyrilene results in decreased methylation of CBLC intron

NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709

G

carbonyl reductase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of CBR3 promoter

NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558

G

cystathionine beta synthase

decreases expression

EXP

Methapyrilene results in decreased expression of CBS mRNA

NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066

G

coiled-coil and C2 domain containing 1B

increases methylation

ISO

Methapyrilene results in increased methylation of CC2D1B exon

NCBI chr 5:128,581,962...128,596,045
Ensembl chr 5:128,581,994...128,596,022

G

cell division cycle and apoptosis regulator 1

decreases expression

EXP

Methapyrilene results in decreased expression of CCAR1 mRNA

NCBI chr20:31,228,624...31,271,233
Ensembl chr20:31,228,624...31,271,227

G

collagen and calcium binding EGF domains 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CCBE1 intron

NCBI chr18:61,849,821...62,093,876
Ensembl chr18:61,853,149...62,094,075

G

coiled-coil domain containing 112

decreases expression

EXP

Methapyrilene results in decreased expression of CCDC112 mRNA

NCBI chr18:41,184,769...41,218,958
Ensembl chr18:41,184,769...41,218,958

G

coiled-coil domain containing 126

increases expression

EXP

Methapyrilene results in increased expression of CCDC126 mRNA

NCBI chr 4:79,628,483...79,649,513
Ensembl chr 4:79,628,412...79,649,508

G

coiled-coil domain containing 127

decreases expression

EXP

Methapyrilene results in decreased expression of CCDC127 mRNA

NCBI chr 1:30,757,010...30,764,473
Ensembl chr 1:30,757,010...30,764,473

G

coiled-coil domain containing 146

affects methylation

ISO

Methapyrilene affects the methylation of CCDC146 intron

NCBI chr 4:14,554,966...14,703,801
Ensembl chr 4:14,554,966...14,703,799

G

coiled-coil domain containing 149

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC149 intron

NCBI chr14:62,722,567...62,817,778
Ensembl chr14:62,722,600...62,817,777

G

coiled-coil domain containing 158

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC158 intron

NCBI chr14:15,695,456...15,752,896
Ensembl chr14:15,695,512...15,752,941

G

coiled-coil domain containing 167

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC167 intron

NCBI chr20:7,768,425...7,783,181
Ensembl chr20:7,753,072...7,783,181

G

coiled-coil domain containing 17

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC17 intron

NCBI chr 5:135,288,799...135,293,339
Ensembl chr 5:135,289,576...135,293,336

G

coiled-coil domain containing 178

decreases methylation

ISO

Methapyrilene results in decreased methylation of CCDC178 intron

NCBI chr18:13,349,795...13,747,083
Ensembl chr18:13,349,399...13,746,974

G

coiled-coil domain containing 18

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC18 intron

NCBI chr14:1,646,725...1,752,581
Ensembl chr14:1,646,809...1,750,470

G

coiled-coil domain containing 30

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC30 intron

NCBI chr 5:138,212,067...138,305,465
Ensembl chr 5:138,211,227...138,304,992

G

coiled-coil domain containing 33

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC33 intron

NCBI chr 8:67,331,519...67,430,194
Ensembl chr 8:67,331,519...67,413,485

G

coiled-coil domain containing 42

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC42 exon

NCBI chr10:53,788,833...53,799,011
Ensembl chr10:53,787,810...53,808,417

G

coiled-coil domain containing 47

decreases expression

EXP

Methapyrilene results in decreased expression of CCDC47 mRNA

NCBI chr10:91,630,101...91,648,626
Ensembl chr10:91,630,106...91,648,626

G

coiled-coil domain containing 57

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC57 intron

NCBI chr10:106,591,106...106,694,740
Ensembl chr10:106,590,551...106,684,983

G

coiled-coil domain containing 63

affects methylation

ISO

Methapyrilene affects the methylation of CCDC63 intron

NCBI chr12:40,085,146...40,113,820
Ensembl chr12:40,085,183...40,114,654

G

coiled-coil domain containing 68

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of CCDC68 intron
Methapyrilene results in decreased expression of CCDC68 mRNA

PMID:30157460 PMID:30467583

NCBI chr18:65,817,232...65,859,529
Ensembl chr18:65,786,926...65,859,526

G

coiled-coil domain containing 70

decreases methylation

ISO

Methapyrilene results in decreased methylation of CCDC70 exon

NCBI chr16:76,739,795...76,745,019
Ensembl chr16:76,738,323...76,745,869

G

coiled-coil domain containing 73

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC73 intron

NCBI chr 3:111,737,771...111,879,588
Ensembl chr 3:111,737,730...111,880,105

G

coiled-coil domain containing 85A

decreases methylation

ISO

Methapyrilene results in decreased methylation of CCDC85A intron

NCBI chr14:106,327,580...106,560,205
Ensembl chr14:106,327,580...106,560,165

G

coiled-coil domain containing 88C

increases methylation

ISO

Methapyrilene results in increased methylation of CCDC88C intron

NCBI chr 6:125,899,337...126,019,162
Ensembl chr 6:125,899,526...126,018,865

G

coiled-coil domain containing 92

decreases methylation

ISO

Methapyrilene results in decreased methylation of CCDC92 intron

NCBI chr12:37,457,676...37,484,080
Ensembl chr12:37,457,068...37,484,327

G

coiled-coil domain containing 97

decreases expression

EXP

Methapyrilene results in decreased expression of CCDC97 mRNA

NCBI chr 1:90,347,003...90,354,809
Ensembl chr 1:90,347,008...90,354,764

G

cholecystokinin B receptor

decreases methylation

ISO

Methapyrilene results in decreased methylation of CCKBR promoter

NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745

G

C-C motif chemokine ligand 2

affects expression
increases expression

EXP

Methapyrilene affects the expression of CCL2 protein
Methapyrilene results in increased expression of CCL2 mRNA; Methapyrilene results in increased expression of CCL2 protein

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 25

increases methylation

ISO

Methapyrilene results in increased methylation of CCL25 intron

NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385

G

C-C motif chemokine ligand 5

increases expression

EXP

Methapyrilene results in increased expression of CCL5 protein

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

cellular communication network factor 1

increases expression

EXP

Methapyrilene results in increased expression of CCN1 mRNA

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

cyclin B1

increases expression

EXP

Methapyrilene results in increased expression of CCNB1 mRNA

PMID:15890375 PMID:22584684

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin B2

increases expression

EXP

Methapyrilene results in increased expression of CCNB2 mRNA

PMID:22484513 PMID:22584684

NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682

G

cyclin D1

increases expression

EXP

Methapyrilene results in increased expression of CCND1 mRNA

PMID:15890375 PMID:22584684

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin F

increases methylation

ISO

Methapyrilene results in increased methylation of CCNF intron

NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,758,421...13,783,837

G

cyclin G1

increases expression

EXP

Methapyrilene results in increased expression of CCNG1 mRNA

PMID:15890375 PMID:28935588

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

cyclin L2

increases expression

EXP

Methapyrilene results in increased expression of CCNL2 mRNA

NCBI chr 5:171,698,951...171,711,037
Ensembl chr 5:171,699,689...171,711,231

G

cyclin Q

decreases expression

EXP

Methapyrilene results in decreased expression of CCNQ mRNA

NCBI chr10:64,144,560...64,145,723
Ensembl chr10:64,144,555...64,145,911

G

cyclin Y

affects methylation

ISO

Methapyrilene affects the methylation of CCNY intron

NCBI chr17:62,079,925...62,207,780
Ensembl chr17:62,079,925...62,207,979

G

centriolar coiled-coil protein 110

increases methylation

ISO

Methapyrilene results in increased methylation of CCP110 promoter

NCBI chr 1:182,475,571...182,504,235
Ensembl chr 1:182,476,422...182,504,232

G

C-C motif chemokine receptor 8

increases methylation

ISO

Methapyrilene results in increased methylation of CCR8 intron

NCBI chr 8:128,703,966...128,705,926
Ensembl chr 8:128,702,349...128,705,955

G

coiled-coil serine-rich protein 1

affects methylation

ISO

Methapyrilene affects the methylation of CCSER1 intron

NCBI chr 4:91,483,896...92,720,439
Ensembl chr 4:91,483,770...92,718,789

G

chaperonin containing TCP1 subunit 3

increases expression

EXP

Methapyrilene results in increased expression of CCT3 mRNA

NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925

G

chaperonin containing TCP1 subunit 4

increases methylation

ISO

Methapyrilene results in increased methylation of CCT4 intron

NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770

G

CD14 molecule

decreases expression

EXP

Methapyrilene results in decreased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

Cd2 (cytoplasmic tail) binding protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of CD2BP2 mRNA

NCBI chr 1:191,239,899...191,244,395
Ensembl chr 1:191,239,901...191,243,398

G

Cd300a molecule

increases methylation

ISO

Methapyrilene results in increased methylation of CD300A intron

NCBI chr10:100,428,826...100,441,693
Ensembl chr10:100,428,826...100,442,958

G

CD300c molecule

increases methylation

ISO

Methapyrilene results in increased methylation of CD300C 3' UTR; Methapyrilene results in increased methylation of CD300C intron

NCBI chr10:100,727,249...100,732,202
Ensembl chr10:100,727,296...100,731,874
Ensembl chr10:100,727,296...100,731,874

G

CD302 molecule

increases expression

EXP

Methapyrilene results in increased expression of CD302 mRNA

NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737

G

CD36 molecule

increases expression
decreases expression

EXP
ISO

Methapyrilene results in increased expression of CD36 mRNA
Methapyrilene results in decreased expression of CD36 mRNA

PMID:28935588 PMID:30467583

NCBI chr 4:18,209,088...18,302,142

G

CD44 molecule

increases expression

ISO

Methapyrilene results in increased expression of CD44 protein

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

Cd6 molecule

increases methylation

ISO

Methapyrilene results in increased methylation of CD6 intron

NCBI chr 1:216,867,767...216,906,642
Ensembl chr 1:216,867,771...216,879,432

G

Cd68 molecule

increases expression

EXP

Methapyrilene results in increased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540

G

Cd81 molecule

increases methylation

ISO

Methapyrilene results in increased methylation of CD81 intron

NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092

G

Cd82 molecule

increases methylation

ISO

Methapyrilene results in increased methylation of CD82 intron

NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:99,842,757...99,886,744

G

CD8 subunit beta

affects methylation

ISO

Methapyrilene affects the methylation of CD8B intron

NCBI chr 4:104,870,911...104,886,838
Ensembl chr 4:104,870,893...104,886,868

G

CD99 molecule-like 2

decreases expression

EXP

Methapyrilene results in decreased expression of CD99L2 mRNA

NCBI chr15:6,861,242...6,906,838
Ensembl chr15:6,864,268...6,906,952

G

cell division cycle 123

increases methylation

ISO

Methapyrilene results in increased methylation of CDC123 intron

NCBI chr17:77,368,376...77,412,659
Ensembl chr17:77,368,397...77,412,659

G

cell division cycle 20

increases expression

EXP

Methapyrilene results in increased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799

G

cell division cycle 27

increases methylation

ISO

Methapyrilene results in increased methylation of CDC27 intron

NCBI chr10:89,900,676...89,949,770
Ensembl chr10:89,900,684...89,949,770

G

cell division cycle 34, ubiquitin conjugating enzyme

increases expression

EXP

Methapyrilene results in increased expression of CDC34 mRNA

NCBI chr 7:10,668,209...10,674,206
Ensembl chr 7:10,668,210...10,674,526

G

cell division cycle 37-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of CDC37L1 mRNA

NCBI chr 1:236,118,630...236,147,527
Ensembl chr 1:236,118,555...236,207,079

G

CDC42 binding protein kinase beta

affects methylation

ISO

Methapyrilene affects the methylation of CDC42BPB intron

NCBI chr 6:136,154,905...136,241,259
Ensembl chr 6:136,154,905...136,237,570

G

cell division cycle 45

increases methylation

ISO

Methapyrilene results in increased methylation of CDC45 intron

NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981

G

cell division cycle 73

decreases methylation

ISO

Methapyrilene results in decreased methylation of CDC73 intron

NCBI chr13:57,897,924...58,000,031
Ensembl chr13:57,883,983...57,999,978

G

cell division cycle associated 3

increases expression

EXP

Methapyrilene results in increased expression of CDCA3 mRNA

NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:159,321,014...159,325,068

G

cell division cycle associated 8

increases expression

EXP

Methapyrilene results in increased expression of CDCA8 mRNA

NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283

G

cadherin 18

decreases methylation

ISO

Methapyrilene results in decreased methylation of CDH18 intron

NCBI chr 2:74,548,681...75,550,720
Ensembl chr 2:75,075,595...75,550,720

G

cadherin 2

decreases expression

EXP

Methapyrilene results in decreased expression of CDH2 mRNA

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cadherin 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of CDH20 intron

NCBI chr13:21,252,272...21,583,526
Ensembl chr13:21,515,123...21,584,349

G

cadherin-related 23

affects methylation
increases methylation
decreases expression

ISO

Methapyrilene affects the methylation of CDH23 intron
Methapyrilene results in increased methylation of CDH23 gene; Methapyrilene results in increased methylation of CDH23 promoter
Methapyrilene results in decreased expression of CDH23 mRNA

PMID:30157460 PMID:31555880

NCBI chr20:28,783,124...29,165,624
Ensembl chr20:28,783,564...29,165,332

G

cadherin 3

increases methylation

ISO

Methapyrilene results in increased methylation of CDH3 intron

NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257

G

cadherin 4

affects methylation

ISO

Methapyrilene affects the methylation of CDH4 intron

NCBI chr 3:186,902,763...187,381,020
Ensembl chr 3:186,902,751...187,381,020

G

cadherin 8

increases methylation

ISO

Methapyrilene results in increased methylation of CDH8 intron

NCBI chr19:5,494,552...5,901,950
Ensembl chr19:5,500,221...5,902,627

G

cadherin-related family member 2

increases methylation

ISO

Methapyrilene results in increased methylation of CDHR2 intron

NCBI chr17:9,881,979...9,917,698
Ensembl chr17:9,881,979...9,917,698

G

cyclin-dependent kinase 1

increases expression

EXP

Methapyrilene results in increased expression of CDK1 mRNA

PMID:15890375 PMID:22584684

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin-dependent kinase 10

decreases expression

EXP

Methapyrilene results in decreased expression of CDK10 mRNA

NCBI chr19:68,168,040...68,184,923
Ensembl chr19:68,169,874...68,177,599

G

cyclin-dependent kinase 14

affects methylation

ISO

Methapyrilene affects the methylation of CDK14 intron

NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651

G

cyclin-dependent kinase 15

increases methylation

ISO

Methapyrilene results in increased methylation of CDK15 intron

NCBI chr 9:68,205,759...68,299,218
Ensembl chr 9:68,205,678...68,293,579

G

cyclin-dependent kinase 16

increases expression

EXP

Methapyrilene results in increased expression of CDK16 mRNA

NCBI chr X:4,046,330...4,057,825
Ensembl chr X:4,026,866...4,057,380

G

cyclin-dependent kinase 4

increases expression

EXP

Methapyrilene results in increased expression of CDK4 mRNA

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin-dependent kinase 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of CDK8 intron

NCBI chr12:13,851,024...13,919,017
Ensembl chr12:13,851,024...13,917,992

G

cyclin-dependent kinase inhibitor 1A

increases expression

EXP

Methapyrilene results in increased expression of CDKN1A mRNA; Methapyrilene results in increased expression of CDKN1A protein

PMID:15890375 PMID:21813463 PMID:25242409 PMID:26558467 PMID:28935588 More...

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 2C

increases expression

EXP

Methapyrilene results in increased expression of CDKN2C mRNA

NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891

G

cyclin-dependent kinase inhibitor 3

increases expression

EXP

Methapyrilene results in increased expression of CDKN3 mRNA

NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722

G

cysteine dioxygenase type 1

decreases expression

EXP

Methapyrilene results in decreased expression of CDO1 mRNA

NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891

G

cell adhesion associated, oncogene regulated

increases methylation

ISO

Methapyrilene results in increased methylation of CDON intron

NCBI chr 8:42,032,921...42,119,451
Ensembl chr 8:42,033,042...42,119,345

G

cerebellar degeneration-related protein 2-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of CDR2L exon

NCBI chr10:101,123,777...101,137,634
Ensembl chr10:101,123,777...101,137,634

G

chromatin licensing and DNA replication factor 1

increases expression

EXP

Methapyrilene results in increased expression of CDT1 mRNA

NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194

G

caudal type homeo box 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CDX2 exon

NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246

G

CEA cell adhesion molecule 1

decreases expression

EXP

Methapyrilene results in decreased expression of CEACAM1 mRNA

NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798

G

CCAAT/enhancer binding protein delta

decreases expression

EXP

Methapyrilene results in decreased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824

G

CCAAT/enhancer binding protein epsilon

decreases methylation

ISO

Methapyrilene results in decreased methylation of CEBPE exon

NCBI chr15:32,139,716...32,141,476
Ensembl chr15:32,139,716...32,141,476

G

CCAAT/enhancer binding protein gamma

decreases expression

EXP

Methapyrilene results in decreased expression of CEBPG mRNA

NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:96,810,214...96,830,283

G

CECR2, histone acetyl-lysine reader

increases methylation

ISO

Methapyrilene results in increased methylation of CECR2 intron

NCBI chr 4:155,562,576...155,670,253
Ensembl chr 4:155,562,727...155,666,741

G

chymotrypsin like elastase 2A

increases methylation

ISO

Methapyrilene results in increased methylation of CELA2A exon

NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:159,409,899...159,426,208

G

CUGBP, Elav-like family member 1

decreases expression

EXP

Methapyrilene results in decreased expression of CELF1 mRNA

NCBI chr 3:97,380,407...97,455,253
Ensembl chr 3:97,380,424...97,452,791

G

CUGBP, Elav-like family member 4

affects methylation

ISO

Methapyrilene affects the methylation of CELF4 intron

NCBI chr18:17,061,284...17,339,747
Ensembl chr18:17,061,293...17,339,571

G

CUGBP, Elav-like family member 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of CELF5 intron

NCBI chr 7:8,876,551...8,901,078
Ensembl chr 7:8,876,564...8,901,069

G

cadherin, EGF LAG seven-pass G-type receptor 1

increases methylation

ISO

Methapyrilene results in increased methylation of CELSR1 intron

NCBI chr 7:118,867,450...119,004,859
Ensembl chr 7:118,867,450...119,004,856

G

cadherin, EGF LAG seven-pass G-type receptor 3

increases methylation

ISO

Methapyrilene results in increased methylation of CELSR3 intron

NCBI chr 8:118,409,136...118,438,593
Ensembl chr 8:118,409,136...118,436,847

G

cell migration inducing hyaluronidase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CEMIP intron

NCBI chr 1:147,316,052...147,471,552
Ensembl chr 1:147,316,052...147,471,768

G

centromere protein P

increases methylation

ISO

Methapyrilene results in increased methylation of CENPP intron

NCBI chr17:15,220,521...15,395,741
Ensembl chr17:15,220,291...15,395,739

G

centrosomal protein 104

increases methylation

ISO

Methapyrilene results in increased methylation of CEP104 intron

NCBI chr 5:169,817,383...169,849,681
Ensembl chr 5:169,817,182...169,852,695

G

centrosomal protein 131

decreases methylation

ISO

Methapyrilene results in decreased methylation of CEP131 intron

NCBI chr10:105,844,433...105,868,811
Ensembl chr10:105,844,433...105,868,797

G

centrosomal protein 152

decreases expression

EXP

Methapyrilene results in decreased expression of CEP152 mRNA

NCBI chr 3:133,243,979...133,332,271
Ensembl chr 3:133,263,174...133,331,655
Ensembl chr 3:133,263,174...133,331,655

G

centrosomal protein 85-like

increases methylation

ISO

Methapyrilene results in increased methylation of CEP85L intron

NCBI chr20:33,111,114...33,282,182
Ensembl chr20:33,115,438...33,282,238

G

ceramide kinase

increases methylation

ISO

Methapyrilene results in increased methylation of CERK intron

NCBI chr 7:119,105,674...119,149,885
Ensembl chr 7:119,105,674...119,148,570

G

ceramide synthase 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of CERS4 intron

NCBI chr12:7,649,610...7,688,066
Ensembl chr12:7,649,610...7,688,070

G

ceramide synthase 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of CERS5 intron

NCBI chr 7:132,738,834...132,776,920
Ensembl chr 7:132,738,834...132,776,786

G

carboxylesterase 2H

increases expression

EXP

Methapyrilene results in increased expression of CES2 mRNA

NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752

G

carboxylesterase 3a

decreases methylation

ISO

Methapyrilene results in decreased methylation of CES3 exon

NCBI chr19:49,902,312...49,910,484

G

carboxylesterase 5A

affects methylation
increases methylation

ISO

Methapyrilene affects the methylation of CES5A intron
Methapyrilene results in increased methylation of CES5A exon

NCBI chr19:11,198,829...11,504,887
Ensembl chr19:11,419,189...11,504,887

G

cilia and flagella associated protein 100

increases methylation

ISO

Methapyrilene results in increased methylation of CFAP100 intron

NCBI chr 4:124,471,913...124,495,990
Ensembl chr 4:124,472,023...124,495,799

G

cilia and flagella associated protein 221

decreases methylation

ISO

Methapyrilene results in decreased methylation of CFAP221 exon

NCBI chr13:33,599,322...33,669,721
Ensembl chr13:33,598,895...33,669,549

G

cilia and flagella associated protein 46

increases methylation

ISO

Methapyrilene results in increased methylation of CFAP46 intron

NCBI chr 1:203,832,818...203,912,389
Ensembl chr 1:203,832,522...203,912,587

G

cilia and flagella associated protein 52

increases methylation

ISO

Methapyrilene results in increased methylation of CFAP52 exon

NCBI chr10:53,112,692...53,153,844
Ensembl chr10:53,112,693...53,153,844

G

cilia and flagella associated protein 61

increases methylation

ISO

Methapyrilene results in increased methylation of CFAP61 exon

NCBI chr 3:153,807,672...154,086,591
Ensembl chr 3:153,807,735...154,086,590

G

cilia and flagella associated protein 70

increases methylation

ISO

Methapyrilene results in increased methylation of CFAP70 intron

NCBI chr15:3,901,544...3,967,224
Ensembl chr15:3,901,610...3,967,220

G

cilia and flagella associated protein 74

increases methylation

ISO

Methapyrilene results in increased methylation of CFAP74 intron; Methapyrilene results in increased methylation of CFAP74 promoter

NCBI chr 5:171,252,907...171,328,351
Ensembl chr 5:171,262,113...171,328,349

G

cilia and flagella associated protein 99

decreases methylation

ISO

Methapyrilene results in decreased methylation of CFAP99 intron

NCBI chr14:80,625,864...80,692,753
Ensembl chr14:80,653,704...80,692,725

G

cofilin 2

decreases expression

EXP

Methapyrilene results in decreased expression of CFL2 mRNA

NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:78,090,843...78,094,888

G

cingulin-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of CGNL1 mRNA

NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747

G

cell growth regulator with EF hand domain 1

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of CGREF1 mRNA
Methapyrilene results in increased methylation of CGREF1 intron

PMID:15890375 PMID:30157460

NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800

G

cell growth regulator with ring finger domain 1

increases expression

EXP

Methapyrilene results in increased expression of CGRRF1 mRNA

NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of CHAC1 mRNA

NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361

G

chromosome alignment maintaining phosphoprotein 1

decreases expression

EXP

Methapyrilene results in decreased expression of CHAMP1 mRNA

NCBI chr16:82,436,172...82,447,144
Ensembl chr16:82,434,823...82,458,984

G

coiled-coil-helix-coiled-coil-helix domain containing 6

increases methylation

ISO

Methapyrilene results in increased methylation of CHCHD6 intron

NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421

G

chromodomain helicase DNA binding protein 1-like

increases methylation

ISO

Methapyrilene results in increased methylation of CHD1L intron

NCBI chr 2:187,819,869...187,906,359
Ensembl chr 2:187,811,954...187,890,477

G

chromodomain helicase DNA binding protein 5

increases methylation

ISO

Methapyrilene results in increased methylation of CHD5 intron

NCBI chr 5:168,130,851...168,181,705
Ensembl chr 5:168,130,575...168,179,441

G

checkpoint kinase 1

increases expression

EXP

Methapyrilene results in increased expression of CHEK1 mRNA

NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359

G

cysteine-rich hydrophobic domain 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CHIC1 intron

NCBI chr X:72,427,851...72,471,924
Ensembl chr X:72,427,851...72,471,924

G

choline kinase alpha

increases expression

EXP

Methapyrilene results in increased expression of CHKA mRNA

NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752

G

charged multivesicular body protein 1A

decreases methylation

ISO

Methapyrilene results in decreased methylation of CHMP1A intron

NCBI chr19:68,146,672...68,154,952
Ensembl chr19:68,146,672...68,154,952

G

charged multivesicular body protein 1B

decreases expression

EXP

Methapyrilene results in decreased expression of CHMP1B mRNA

NCBI chr18:63,010,270...63,012,800
Ensembl chr18:63,010,251...63,011,415

G

charged multivesicular body protein 2A

decreases expression

EXP

Methapyrilene results in decreased expression of CHMP2A mRNA

NCBI chr 1:82,731,212...82,735,088
Ensembl chr 1:82,732,231...82,738,613

G

chimerin 2

affects methylation

ISO

Methapyrilene affects the methylation of CHN2 intron

NCBI chr 4:84,478,989...84,738,068
Ensembl chr 4:84,704,862...84,738,068

G

cholinergic receptor nicotinic alpha 2 subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of CHRNA2 3' UTR

NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144

G

cholinergic receptor nicotinic beta 3 subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of CHRNB3 intron

NCBI chr16:71,411,847...71,454,225
Ensembl chr16:71,417,039...71,454,225

G

carbohydrate sulfotransferase 11

increases methylation

ISO

Methapyrilene results in increased methylation of CHST11 intron

NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:22,415,686...22,630,441

G

carbohydrate sulfotransferase 8

increases methylation

ISO

Methapyrilene results in increased methylation of CHST8 intron

NCBI chr 1:96,431,144...96,572,880
Ensembl chr 1:96,431,145...96,572,880

G

calcium and integrin binding family member 2

increases methylation

ISO

Methapyrilene results in increased methylation of CIB2 exon

NCBI chr 8:63,826,410...63,843,301
Ensembl chr 8:63,826,411...63,843,277

G

calcium and integrin binding family member 4

increases methylation

ISO

Methapyrilene results in increased methylation of CIB4 intron

NCBI chr 6:31,560,105...31,623,403
Ensembl chr 6:31,562,489...31,623,464

G

CIMAP1 family member D

increases methylation

ISO

Methapyrilene results in increased methylation of CIMAP1D promoter

NCBI chr 7:10,700,067...10,715,742
Ensembl chr 7:10,700,510...10,715,738

G

ciliary microtubule inner protein 2C

decreases methylation

ISO

Methapyrilene results in decreased methylation of CIMIP2C intron

NCBI chr 6:31,625,187...31,643,500
Ensembl chr 6:31,625,188...31,643,629

G

cold inducible RNA binding protein

decreases expression

EXP

Methapyrilene results in decreased expression of CIRBP mRNA

NCBI chr 7:10,184,515...10,189,623

G

ciliated left-right organizer protein containing ZP-N domains

decreases methylation

ISO

Methapyrilene results in decreased methylation of CIROZ promoter

NCBI chr 5:164,358,333...164,393,758
Ensembl chr 5:164,358,306...164,388,485

G

citron rho-interacting serine/threonine kinase

increases methylation

ISO

Methapyrilene results in increased methylation of CIT intron

NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

EXP

Methapyrilene results in decreased expression of CITED2 mRNA

NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782

G

cytoskeleton associated protein 2

decreases methylation
increases expression

ISO
EXP

Methapyrilene results in decreased methylation of CKAP2 exon
Methapyrilene results in increased expression of CKAP2 mRNA

PMID:30157460 PMID:30467583

NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352

G

cytoskeleton-associated protein 4

decreases expression

EXP

Methapyrilene results in decreased expression of CKAP4 mRNA

NCBI chr 7:21,118,527...21,126,624
Ensembl chr 7:21,118,085...21,126,624

G

cytoskeleton associated protein 5

increases expression

EXP

Methapyrilene results in increased expression of CKAP5 mRNA

NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049

G

CDC28 protein kinase regulatory subunit 2

increases expression

EXP

Methapyrilene results in increased expression of CKS2 mRNA

NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519

G

chloride channel CLIC-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of CLCC1 mRNA

NCBI chr 2:198,984,455...199,015,015
Ensembl chr 2:198,984,495...199,015,014

G

chloride voltage-gated channel 3

decreases expression

EXP

Methapyrilene results in decreased expression of CLCN3 mRNA

NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984

G

chloride voltage-gated channel 4

decreases expression

EXP

Methapyrilene results in decreased expression of CLCN4 mRNA

PMID:16393664 PMID:30467583

NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939

G

chloride voltage-gated channel Kb

decreases methylation

ISO

Methapyrilene results in decreased methylation of CLCNKB intron

NCBI chr 5:158,993,073...159,005,618
Ensembl chr 5:158,993,074...159,004,900

G

claudin 1

decreases expression

EXP

Methapyrilene results in decreased expression of CLDN1 mRNA

NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529

G

claudin 2

decreases expression

EXP

Methapyrilene results in decreased expression of CLDN2 mRNA

NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377

G

claudin 4

increases methylation

ISO

Methapyrilene results in increased methylation of CLDN4 promoter

NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958

G

C-type lectin domain containing 11A

increases methylation

ISO

Methapyrilene results in increased methylation of CLEC11A polyA tail

NCBI chr 1:103,938,029...103,941,170
Ensembl chr 1:103,935,185...103,946,784

G

C-type lectin domain family 1, member B

increases expression

EXP

Methapyrilene results in increased expression of CLEC1B mRNA

NCBI chr 4:164,533,987...164,542,320
Ensembl chr 4:164,534,055...164,542,867

G

C-type lectin domain family 4, member F

increases methylation

ISO

Methapyrilene results in increased methylation of CLEC4F intron

NCBI chr 4:117,686,686...117,696,407
Ensembl chr 4:117,686,686...117,696,438

G

CAP-GLY domain containing linker protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of CLIP1 mRNA

NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779

G

CDC-like kinase 1

increases expression

EXP

Methapyrilene results in increased expression of CLK1 mRNA

NCBI chr 9:67,441,962...67,453,180
Ensembl chr 9:67,441,952...67,451,187

G

CDC-like kinase 3

affects methylation

ISO

Methapyrilene affects the methylation of CLK3 intron

NCBI chr 8:67,048,121...67,063,192
Ensembl chr 8:67,048,123...67,062,881

G

calmin

increases methylation

ISO

Methapyrilene results in increased methylation of CLMN intron

NCBI chr 6:129,470,613...129,572,079
Ensembl chr 6:129,478,149...129,572,027

G

CLN5, intracellular trafficking protein

decreases expression

EXP

Methapyrilene results in decreased expression of CLN5 mRNA

NCBI chr15:86,308,286...86,321,679
Ensembl chr 2:67,620,667...67,622,952
Ensembl chr15:67,620,667...67,622,952

G

CLN6, transmembrane ER protein

increases methylation

ISO

Methapyrilene results in increased methylation of CLN6 intron

NCBI chr 8:72,198,773...72,213,777
Ensembl chr 8:72,198,712...72,213,776

G

cleavage factor polyribonucleotide kinase subunit 1

increases expression

EXP

Methapyrilene results in increased expression of CLP1 mRNA

NCBI chr 3:90,213,461...90,217,165
Ensembl chr 3:90,213,465...90,217,538

G

CLPTM1 regulator of GABA type A receptor forward trafficking

affects methylation

ISO

Methapyrilene affects the methylation of CLPTM1 intron

NCBI chr 1:88,417,447...88,449,047
Ensembl chr 1:88,417,447...88,449,446

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

decreases expression

EXP

Methapyrilene results in decreased expression of CLPX mRNA

NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762

G

clarin 2

increases methylation

ISO

Methapyrilene results in increased methylation of CLRN2 intron

NCBI chr14:69,868,556...69,878,850
Ensembl chr14:69,868,556...69,878,850

G

calsyntenin 2

increases methylation

ISO

Methapyrilene results in increased methylation of CLSTN2 exon

NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:106,899,894...107,040,053

G

collectrin, amino acid transport regulator

decreases methylation

ISO

Methapyrilene results in decreased methylation of CLTRN intron

NCBI chr X:33,993,825...34,027,124
Ensembl chr X:33,993,825...34,027,181

G

carboxymethylenebutenolidase homolog

decreases expression

EXP

Methapyrilene results in decreased expression of CMBL mRNA

NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880

G

c-Maf-inducing protein

affects methylation

ISO

Methapyrilene affects the methylation of CMIP intron

NCBI chr19:62,213,402...62,419,443
Ensembl chr19:62,213,365...62,417,500

G

cytidine/uridine monophosphate kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of CMPK2 intron

NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:48,802,321...48,813,652

G

cyclic nucleotide binding domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of CNBD1 intron

NCBI chr 5:37,030,954...37,403,996
Ensembl chr 5:37,030,362...37,403,752

G

carnosine dipeptidase 1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of CNDP1 intron
Methapyrilene results in decreased expression of CNDP1 mRNA

PMID:30157460 PMID:30467583

NCBI chr18:80,254,499...80,305,845
Ensembl chr18:80,255,784...80,282,643

G

carnosine dipeptidase 2

decreases expression

EXP

Methapyrilene results in decreased expression of CNDP2 mRNA

NCBI chr18:80,314,799...80,331,900
Ensembl chr18:80,314,801...80,331,900

G

cyclic nucleotide gated channel subunit alpha 4

increases methylation

ISO

Methapyrilene results in increased methylation of CNGA4 intron

NCBI chr 1:169,134,332...169,168,317
Ensembl chr 1:169,164,206...169,168,224

G

cornichon family AMPA receptor auxiliary protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of CNIH3 intron

NCBI chr13:95,548,440...95,739,500
Ensembl chr13:95,598,998...95,772,064

G

cyclin and CBS domain divalent metal cation transport mediator 3

increases methylation

ISO

Methapyrilene results in increased methylation of CNNM3 exon

NCBI chr 9:46,251,252...46,266,613
Ensembl chr 9:46,251,265...46,266,613

G

CCR4-NOT transcription complex, subunit 1

decreases expression

EXP

Methapyrilene results in decreased expression of CNOT1 mRNA

NCBI chr19:9,261,290...9,352,636
Ensembl chr19:9,261,294...9,352,636

G

CCR4-NOT transcription complex, subunit 3

increases methylation

ISO

Methapyrilene results in increased methylation of CNOT3 exon

NCBI chr 1:74,471,284...74,487,527
Ensembl chr 1:74,470,566...74,487,527

G

CCR4-NOT transcription complex, subunit 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of CNOT6 intron

NCBI chr10:34,479,892...34,532,166
Ensembl chr10:34,481,938...34,524,416

G

CCR4-NOT transcription complex, subunit 6-like

decreases expression

EXP

Methapyrilene results in decreased expression of CNOT6L mRNA

NCBI chr14:13,714,475...13,806,481
Ensembl chr14:13,714,475...13,806,481

G

2',3'-cyclic nucleotide 3' phosphodiesterase

decreases expression

EXP

Methapyrilene results in decreased expression of CNP mRNA

NCBI chr10:86,011,504...86,018,063
Ensembl chr10:86,011,495...86,018,063

G

canopy FGF signaling regulator 1

increases methylation

ISO

Methapyrilene results in increased methylation of CNPY1 intron

NCBI chr 4:7,870,403...7,925,266
Ensembl chr 4:7,869,829...7,925,266

G

cannabinoid receptor 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CNR2 intron

NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961

G

ciliary neurotrophic factor receptor

increases methylation

ISO

Methapyrilene results in increased methylation of CNTFR intron

NCBI chr 5:61,619,326...61,657,359
Ensembl chr 5:61,619,326...61,645,795

G

centlein

decreases methylation

ISO

Methapyrilene results in decreased methylation of CNTLN intron

NCBI chr 5:104,340,801...104,622,491
Ensembl chr 5:104,342,173...104,630,976

G

contactin 1

affects methylation

ISO

Methapyrilene affects the methylation of CNTN1 intron

NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391

G

contactin 4

affects methylation

ISO

Methapyrilene affects the methylation of CNTN4 intron

NCBI chr 4:140,180,696...141,177,771
Ensembl chr 4:140,596,284...141,177,766

G

contactin 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of CNTN5 intron

NCBI chr 8:15,017,424...16,249,418
Ensembl chr 8:15,018,927...15,969,060

G

cytochrome C oxidase assembly factor 5

decreases expression

EXP

Methapyrilene results in decreased expression of COA5 mRNA

NCBI chr 9:47,147,267...47,160,724
Ensembl chr 9:47,147,267...47,160,672

G

Coenzyme A synthase

decreases expression

EXP

Methapyrilene results in decreased expression of COASY mRNA

NCBI chr10:86,514,850...86,519,130
Ensembl chr10:86,514,874...86,519,130

G

cordon-bleu WH2 repeat protein-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of COBLL1 mRNA

NCBI chr 3:70,161,369...70,324,844
Ensembl chr 3:70,161,372...70,323,460

G

component of oligomeric golgi complex 7

decreases expression

EXP

Methapyrilene results in decreased expression of COG7 mRNA

NCBI chr 1:185,921,053...185,980,711
Ensembl chr 1:185,889,348...185,983,421

G

component of oligomeric golgi complex 8

increases methylation

ISO

Methapyrilene results in increased methylation of COG8 exon

NCBI chr19:51,861,376...51,872,126
Ensembl chr19:51,861,376...51,872,129

G

collagen type XI alpha 2 chain

increases methylation

ISO

Methapyrilene results in increased methylation of COL11A2 intron

NCBI chr20:4,788,829...4,818,492
Ensembl chr20:4,788,829...4,817,648

G

collagen type XIII alpha 1 chain

affects methylation

ISO

Methapyrilene affects the methylation of COL13A1 intron

NCBI chr20:30,326,744...30,466,800
Ensembl chr20:30,326,744...30,466,800

G

collagen type XVI alpha 1 chain

increases methylation

ISO

Methapyrilene results in increased methylation of COL16A1 5' UTR

NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011

G

collagen type XVII alpha 1 chain

decreases methylation

ISO

Methapyrilene results in decreased methylation of COL17A1 exon

NCBI chr 1:256,472,648...256,518,857
Ensembl chr 1:256,472,648...256,518,851

G

collagen type XVIII alpha 1 chain

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of COL18A1 intron
Methapyrilene results in increased methylation of COL18A1 promoter

NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112

G

collagen type I alpha 2 chain

increases expression

EXP

Methapyrilene results in increased expression of COL1A2 mRNA

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type XX alpha 1 chain

decreases methylation

ISO

Methapyrilene results in decreased methylation of COL20A1 intron

NCBI chr 3:188,477,663...188,512,326
Ensembl chr 3:188,465,648...188,511,078

G

collagen type XXII alpha 1 chain

increases methylation

ISO

Methapyrilene results in increased methylation of COL22A1 intron

NCBI chr 7:105,619,776...105,857,246
Ensembl chr 7:105,619,757...105,856,960

G

collagen type XXIII alpha 1 chain

affects methylation

ISO

Methapyrilene affects the methylation of COL23A1 intron

NCBI chr10:36,050,327...36,337,279
Ensembl chr10:36,050,259...36,337,897

G

collagen type II alpha 1 chain

affects methylation

ISO

Methapyrilene affects the methylation of COL2A1 exon

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

collagen type IV alpha 1 chain

increases expression

EXP

Methapyrilene results in increased expression of COL4A1 mRNA

NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482

G

collagen type IV alpha 2 chain

decreases methylation

ISO

Methapyrilene results in decreased methylation of COL4A2 intron

NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520

G

collagen type IV alpha 3 chain

decreases methylation

ISO

Methapyrilene results in decreased methylation of COL4A3 intron

NCBI chr 9:91,323,990...91,453,088
Ensembl chr 9:91,323,990...91,453,077

G

collagen type IV alpha 5 chain

affects methylation

ISO

Methapyrilene affects the methylation of COL4A5 intron

NCBI chr X:109,907,251...110,111,214
Ensembl chr X:109,907,346...110,111,214

G

collagen type IV alpha 6 chain

decreases methylation

ISO

Methapyrilene results in decreased methylation of COL4A6 intron

NCBI chr X:109,554,945...109,905,987
Ensembl chr X:109,552,651...109,905,944

G

collagen type V alpha 1 chain

affects methylation

ISO

Methapyrilene affects the methylation of COL5A1 intron

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020

G

collagen type V alpha 2 chain

increases expression

ISO

Methapyrilene results in increased expression of COL5A2 mRNA

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type VIII alpha 2 chain

increases methylation

ISO

Methapyrilene results in increased methylation of COL8A2 exon; Methapyrilene results in increased methylation of COL8A2 intron

NCBI chr 5:143,870,754...143,897,372
Ensembl chr 5:143,870,742...143,897,884

G

collagen type IX alpha 2 chain

increases methylation

ISO

Methapyrilene results in increased methylation of COL9A2 exon

NCBI chr 5:139,892,798...139,910,131
Ensembl chr 5:139,892,798...139,909,855

G

collagen type IX alpha 3 chain

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of COL9A3 intron
Methapyrilene results in increased methylation of COL9A3 exon

NCBI chr 3:188,089,337...188,112,034
Ensembl chr 3:188,089,403...188,112,270

G

collagen beta(1-O)galactosyltransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of COLGALT1 intron

NCBI chr16:18,353,779...18,366,087
Ensembl chr16:18,353,570...18,366,086

G

collagen like tail subunit of asymmetric acetylcholinesterase

increases methylation

ISO

Methapyrilene results in increased methylation of COLQ exon; Methapyrilene results in increased methylation of COLQ intron

NCBI chr16:6,738,251...6,830,492
Ensembl chr16:6,738,251...6,793,501

G

COMM domain containing 5

decreases expression

EXP

Methapyrilene results in decreased expression of COMMD5 mRNA

NCBI chr 7:110,502,492...110,503,916
Ensembl chr 7:110,479,403...110,505,897

G

catechol-O-methyltransferase

decreases methylation

ISO

Methapyrilene results in decreased methylation of COMT intron

NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533

G

COPI coat complex subunit beta 1

decreases expression

EXP

Methapyrilene results in decreased expression of COPB1 mRNA

NCBI chr 1:177,838,751...177,876,688
Ensembl chr 1:177,838,752...177,872,840

G

COPI coat complex subunit gamma 1

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of COPG1 intron
Methapyrilene results in decreased expression of COPG1 mRNA

PMID:30157460 PMID:30467583

NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812

G

COP9 signalosome subunit 7A

decreases expression

EXP

Methapyrilene results in decreased expression of COPS7A mRNA

NCBI chr 4:159,452,878...159,478,878
Ensembl chr 4:159,452,897...159,460,315

G

coenzyme Q7, hydroxylase

increases methylation

ISO

Methapyrilene results in increased methylation of COQ7 intron

NCBI chr 1:182,270,570...182,285,959
Ensembl chr 1:182,269,399...182,285,508

G

coenzyme Q8A

decreases expression

EXP

Methapyrilene results in decreased expression of ADCK3 mRNA

NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378

G

corin, serine peptidase

increases methylation

ISO

Methapyrilene results in increased methylation of CORIN intron

NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649

G

coronin 2A

increases methylation

ISO

Methapyrilene results in increased methylation of CORO2A intron

NCBI chr 5:65,623,820...65,677,483
Ensembl chr 5:65,623,823...65,654,602

G

coronin 2B

increases methylation

ISO

Methapyrilene results in increased methylation of CORO2B intron

NCBI chr 8:71,802,329...71,912,739
Ensembl chr 8:71,802,329...71,912,739

G

coronin 7

increases methylation

ISO

Methapyrilene results in increased methylation of CORO7 intron

NCBI chr10:11,386,683...11,447,422
Ensembl chr10:11,391,613...11,447,866

G

ceruloplasmin

increases expression

ISO

Methapyrilene results in increased expression of CP mRNA

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087

G

carboxypeptidase A2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CPA2 exon

NCBI chr 4:60,125,297...60,151,066
Ensembl chr 4:60,118,682...60,183,448

G

centrosome assembly and centriole elongation protein

increases methylation

ISO

Methapyrilene results in increased methylation of CPAP intron

NCBI chr15:34,742,838...34,806,020
Ensembl chr15:34,742,838...34,802,421

G

carboxypeptidase D

decreases expression

EXP

Methapyrilene results in decreased expression of CPD mRNA

NCBI chr10:62,121,681...62,185,638
Ensembl chr10:62,121,679...62,185,638

G

carboxypeptidase N subunit 1

decreases expression

EXP

Methapyrilene results in decreased expression of CPN1 mRNA

NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664

G

copine 2

increases methylation

ISO

Methapyrilene results in increased methylation of CPNE2 intron

NCBI chr19:10,440,245...10,477,783
Ensembl chr19:10,434,647...10,477,783

G

copine 3

decreases expression

EXP

Methapyrilene results in decreased expression of CPNE3 mRNA

NCBI chr 5:37,811,566...37,860,840
Ensembl chr 5:37,811,566...37,861,062

G

copine 4

increases methylation

EXP

Methapyrilene results in increased methylation of CPNE4 gene

NCBI chr 8:114,056,152...114,531,855
Ensembl chr 8:113,993,703...114,531,855

G

copine 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of CPNE5 exon; Methapyrilene results in decreased methylation of CPNE5 intron

NCBI chr20:7,208,389...7,290,959
Ensembl chr20:7,208,389...7,292,064

G

copine 8

decreases expression

EXP

Methapyrilene results in decreased expression of CPNE8 mRNA

NCBI chr 7:123,494,864...123,669,060
Ensembl chr 7:123,494,865...123,669,060

G

coproporphyrinogen oxidase

decreases expression

EXP

Methapyrilene results in decreased expression of CPOX mRNA

NCBI chr11:55,405,778...55,415,761
Ensembl chr11:55,405,784...55,415,761

G

calcineurin-like phosphoesterase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of CPPED1 mRNA

NCBI chr10:4,135,601...4,328,039
Ensembl chr10:4,208,463...4,231,065

G

carboxypeptidase Q

increases expression

EXP

Methapyrilene results in increased expression of PGCP mRNA

NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137

G

carbamoyl-phosphate synthase 1

decreases expression

EXP

Methapyrilene results in decreased expression of CPS1 mRNA

NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734

G

carnitine palmitoyltransferase 1A

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of CPT1A mRNA
Methapyrilene results in increased methylation of CPT1A intron

PMID:15120968 PMID:30157460 PMID:30467583

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326

G

carnitine palmitoyltransferase 1c

decreases methylation

ISO

Methapyrilene results in decreased methylation of CPT1C exon

NCBI chr 1:104,579,297...104,593,824
Ensembl chr 1:104,579,298...104,593,763

G

carboxypeptidase Z

increases methylation

ISO

Methapyrilene results in increased methylation of CPZ intron

NCBI chr14:79,448,242...79,471,557
Ensembl chr14:79,448,139...79,471,556

G

complement C3b/C4b receptor 1 like

increases expression

EXP

Methapyrilene results in increased expression of CR1L mRNA

NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869

G

cellular retinoic acid binding protein 1

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of CRABP1 intron
Methapyrilene results in decreased methylation of CRABP1 promoter

NCBI chr 8:64,047,431...64,055,469
Ensembl chr 8:64,047,060...64,055,470

G

capping protein inhibiting regulator of actin dynamics

increases methylation

EXP

Methapyrilene results in increased methylation of CRACD gene

NCBI chr14:31,638,328...31,874,391
Ensembl chr14:31,638,328...31,683,987

G

calcium release activated channel regulator 2A

increases methylation

ISO

Methapyrilene results in increased methylation of CRACR2A intron

NCBI chr 4:162,094,247...162,207,926
Ensembl chr 4:162,110,929...162,221,529

G

crumbs cell polarity complex component 1

affects methylation

ISO

Methapyrilene affects the methylation of CRB1 intron

NCBI chr13:53,352,932...53,540,019
Ensembl chr13:53,352,932...53,540,019

G

crumbs cell polarity complex component 3

decreases expression

EXP

Methapyrilene results in decreased expression of CRB3 mRNA

NCBI chr 9:1,985,504...1,990,855
Ensembl chr 9:1,983,619...1,993,486

G

cAMP responsive element binding protein 3-like 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of CREB3L3 intron

NCBI chr 7:9,273,320...9,281,755
Ensembl chr 7:9,273,338...9,281,778

G

cAMP responsive element binding protein 5

affects methylation

ISO

Methapyrilene affects the methylation of CREB5 intron

NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793

G

CREB binding protein

decreases expression

EXP

Methapyrilene results in decreased expression of CREBBP mRNA

NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266

G

CREB/ATF bZIP transcription factor

decreases expression

EXP

Methapyrilene results in decreased expression of CREBZF mRNA

NCBI chr 1:153,829,544...153,836,073
Ensembl chr 1:153,829,448...153,845,122

G

cysteine rich transmembrane BMP regulator 1

increases methylation

ISO

Methapyrilene results in increased methylation of CRIM1 exon

NCBI chr 6:22,447,983...22,622,459
Ensembl chr 6:22,449,948...22,622,416

G

collapsin response mediator protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of CRMP1 intron

NCBI chr14:77,734,675...77,780,916
Ensembl chr14:77,734,675...77,780,916

G

carnitine O-octanoyltransferase

decreases expression

EXP

Methapyrilene results in decreased expression of CROT mRNA

NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064

G

cartilage acidic protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of CRTAC1 intron

NCBI chr 1:251,040,963...251,182,920
Ensembl chr 1:251,028,143...251,182,689

G

cytotoxic and regulatory T cell molecule

increases methylation

ISO

Methapyrilene results in increased methylation of CRTAM intron

NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:50,237,210...50,274,472

G

CREB regulated transcription coactivator 1

increases methylation

ISO

Methapyrilene results in increased methylation of CRTC1 3' UTR; Methapyrilene results in increased methylation of CRTC1 intron

NCBI chr16:19,022,171...19,080,880
Ensembl chr16:19,022,005...19,080,880

G

CREB regulated transcription coactivator 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of CRTC3 intron

NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:143,962,038...144,064,288

G

cone-rod homeobox

increases methylation

ISO

Methapyrilene results in increased methylation of CRX 3' UTR

NCBI chr 1:85,667,971...85,681,852
Ensembl chr 1:85,667,971...85,681,852

G

crystallin beta-gamma domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of AIM1L exon

NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:151,570,540...151,602,163

G

crystallin, lambda 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CRYL1 intron

NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563

G

cysteine sulfinic acid decarboxylase

decreases expression

EXP

Methapyrilene results in decreased expression of CSAD mRNA

NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581

G

colony stimulating factor 2 receptor subunit beta

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of CSF2RB exon; Methapyrilene results in increased methylation of CSF2RB promoter
Methapyrilene results in decreased methylation of CSF2RB intron

NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654

G

CUB and Sushi multiple domains 1

affects methylation

ISO

Methapyrilene affects the methylation of CSMD1 intron

NCBI chr16:78,920,549...80,520,710
Ensembl chr16:78,921,002...80,519,944

G

CUB and Sushi multiple domains 2

increases methylation

ISO

Methapyrilene results in increased methylation of CSMD2 intron

NCBI chr 5:145,626,823...146,196,815
Ensembl chr 5:145,626,845...146,196,812

G

CUB and Sushi multiple domains 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of CSMD3 intron

NCBI chr 7:80,637,341...81,956,469
Ensembl chr 7:80,638,143...81,956,162

G

casein kinase 1, gamma 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CSNK1G2 intron

NCBI chr 7:9,727,430...9,746,341
Ensembl chr 7:9,727,431...9,745,741

G

casein kinase 2 alpha 1

increases methylation

ISO

Methapyrilene results in increased methylation of CSNK2A1 intron

NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698

G

centrosome and spindle pole associated protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CSPP1 intron

NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:13,860,072...13,975,321

G

cysteine and serine rich nuclear protein 1

increases expression

EXP

Methapyrilene results in increased expression of CSRNP1 mRNA

NCBI chr 8:128,582,364...128,594,163
Ensembl chr 8:128,582,365...128,588,469

G

cysteine and glycine-rich protein 2

increases expression

EXP

Methapyrilene results in increased expression of CSRP2 mRNA

NCBI chr 7:48,235,415...48,254,049
Ensembl chr 7:48,235,383...48,266,238

G

cystatin 12

increases expression

EXP

Methapyrilene results in increased expression of CST12 mRNA

NCBI chr 3:156,688,155...156,692,052
Ensembl chr 3:156,688,049...156,692,052

G

cystatin C

increases expression

EXP

Methapyrilene results in increased expression of CST3 mRNA

NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937

G

cystatin B

increases expression

EXP

Methapyrilene results in increased expression of CSTB mRNA

PMID:15890375 PMID:30467583

NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199

G

cleavage stimulation factor subunit 2, tau variant

decreases expression

EXP

Methapyrilene results in decreased expression of CSTF2T mRNA

NCBI chr 1:238,366,042...238,369,608
Ensembl chr 1:238,365,912...238,369,749

G

C-terminal binding protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CTBP2 intron

NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261

G

CCCTC-binding factor like 1

increases methylation

ISO

Methapyrilene results in increased methylation of CTCFL intron

NCBI chr 3:182,286,637...182,309,272
Ensembl chr 3:182,286,637...182,309,272

G

CTD small phosphatase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CTDSP2 intron

NCBI chr 7:64,690,737...64,710,639
Ensembl chr 7:64,690,490...64,710,639

G

CTD small phosphatase like 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of CTDSPL2 intron

NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:129,368,938...129,424,232

G

cardiotrophin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CTF1 intron

NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395

G

cystathionine gamma-lyase

decreases expression

EXP

Methapyrilene results in decreased expression of CTH mRNA

PMID:16393664 PMID:30467583

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066

G

cap binding complex dependent translation initiation factor

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of CTIF intron
Methapyrilene results in increased methylation of CTIF 3' UTR

NCBI chr18:71,331,222...71,602,493
Ensembl chr18:71,307,314...71,602,492

G

catenin alpha-like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CTNNAL1 intron

NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637

G

cystinosin, lysosomal cystine transporter

decreases methylation

ISO

Methapyrilene results in decreased methylation of CTNS intron

NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661

G

CTP synthase 2

increases methylation

ISO

Methapyrilene results in increased methylation of CTPS2 intron

NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505

G

cathepsin C

decreases expression

EXP

Methapyrilene results in decreased expression of CTSC mRNA

NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082

G

cathepsin D

increases expression

EXP

Methapyrilene results in increased expression of CTSD mRNA

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cut-like homeobox 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CUX1 intron

NCBI chr12:25,728,393...26,062,497
Ensembl chr12:25,743,733...26,062,497

G

cut-like homeobox 2

increases methylation

ISO

Methapyrilene results in increased methylation of CUX2 intron

NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528

G

CXADR, Ig-like cell adhesion molecule

increases expression

EXP

Methapyrilene results in increased expression of CXADR mRNA

NCBI chr11:30,469,778...30,516,990
Ensembl chr11:30,469,526...30,516,988

G

C-X-C motif chemokine ligand 1

decreases expression

EXP

Methapyrilene results in decreased expression of CXCL1 protein

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of CXCL10 mRNA
Methapyrilene results in decreased expression of CXCL10 protein

PMID:15890375 PMID:25051504

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 12

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of CXCL12 mRNA
Methapyrilene results in increased methylation of CXCL12 intron

PMID:28935588 PMID:30157460

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 9

increases expression

EXP

Methapyrilene results in increased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299

G

cytochrome b5 type A

decreases expression

EXP

Methapyrilene results in decreased expression of CYB5A mRNA

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094

G

cytoplasmic FMR1 interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of CYFIP1 intron

NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292

G

cytoplasmic FMR1 interacting protein 2

affects methylation

ISO

Methapyrilene affects the methylation of CYFIP2 intron

NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440

G

CYLD lysine 63 deubiquitinase

increases expression

EXP

Methapyrilene results in increased expression of CYLD mRNA

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 20, subfamily a, polypeptide 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP20A1 mRNA

NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291

G

cytochrome P450, family 27, subfamily a, polypeptide 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP27A1 mRNA

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215

G

cytochrome P450, family 27, subfamily b, polypeptide 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of CYP27B1 exon

NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570

G

cytochrome P450, subfamily 2, polypeptide 11

decreases activity

EXP

Methapyrilene results in decreased activity of CYP2C11 protein

NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853

G

cytochrome P450, family 2, subfamily c, polypeptide 13

increases expression

EXP

Methapyrilene results in increased expression of CYP2C13 mRNA

NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210

G

cytochrome P450, family 2, subfamily c, polypeptide 7

decreases expression

EXP

Methapyrilene results in decreased expression of CYP2C7 mRNA

NCBI chr 1:247,966,295...248,022,393
Ensembl chr 1:247,966,346...248,022,388

G

cytochrome P450, family 2, subfamily d, polypeptide 2

increases expression

EXP

Methapyrilene results in increased expression of CYP2D2 mRNA

NCBI chr 7:115,815,212...115,819,281
Ensembl chr 7:115,815,212...115,819,281

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases expression

EXP

Methapyrilene results in decreased expression of CYP2D4 mRNA

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

ISO
EXP

Methapyrilene results in decreased expression of CYP2E1 mRNA

PMID:28935588 PMID:30467583

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily f, polypeptide 4

decreases expression

EXP

Methapyrilene results in decreased expression of CYP2F4 mRNA

NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553

G

cytochrome P450, family 2, subfamily j, polypeptide 3

decreases expression

EXP

Methapyrilene results in decreased expression of CYP2J3 mRNA

NCBI chr 5:116,335,755...116,360,677
Ensembl chr 5:116,335,755...116,360,499

G

cytochrome P450, family 2, subfamily j, polypeptide 4

decreases expression

EXP

Methapyrilene results in decreased expression of CYP2J4 mRNA

NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042

G

cytochrome P450, family 3, subfamily a, polypeptide 18

increases expression

EXP

Methapyrilene results in increased expression of CYP3A18 mRNA

NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP3A23-3A1 mRNA

NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813

G

cytochrome P450, family 4, subfamily a, polypeptide 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP4A1 mRNA

NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231

G

cytochrome P450, family 4, subfamily a, polypeptide 3

decreases expression

EXP

Methapyrilene results in decreased expression of CYP4A3 mRNA

NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236

G

cytochrome P450, family 4, subfamily v, polypeptide 3

decreases expression

EXP

Methapyrilene results in decreased expression of CYP4V3 mRNA

NCBI chr16:53,650,978...53,675,916
Ensembl chr16:53,650,569...53,676,746

G

cytochrome P450, family 51

increases expression

EXP

Methapyrilene results in increased expression of CYP51 mRNA

NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450

G

cytochrome P450 family 7 subfamily A member 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

cytochrome P450 family 7 subfamily B member 1

increases methylation

ISO

Methapyrilene results in increased methylation of CYP7B1 intron

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

EXP

Methapyrilene results in decreased expression of CYP8B1 mRNA

NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689

G

CYFIP related Rac1 interactor A

increases methylation

ISO

Methapyrilene results in increased methylation of CYRIA intron

NCBI chr 6:40,774,165...40,883,005
Ensembl chr 6:40,774,171...40,881,860

G

CYFIP related Rac1 interactor B

increases methylation

ISO

Methapyrilene results in increased methylation of CYRIB promoter

NCBI chr 7:97,524,941...97,649,846
Ensembl chr 7:97,523,121...97,649,853

G

cytohesin 4

increases methylation

ISO

Methapyrilene results in increased methylation of CYTH4 intron

NCBI chr 7:112,032,711...112,057,204
Ensembl chr 7:112,032,775...112,057,204

G

dishevelled associated activator of morphogenesis 1

decreases expression

EXP

Methapyrilene results in decreased expression of DAAM1 mRNA

NCBI chr 6:96,125,521...96,286,049
Ensembl chr 6:96,125,621...96,286,049

G

dishevelled associated activator of morphogenesis 2

increases methylation

ISO

Methapyrilene results in increased methylation of DAAM2 intron

NCBI chr 9:18,926,620...19,044,672
Ensembl chr 9:18,926,623...19,044,671

G

DAB adaptor protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of DAB1 intron

NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584

G

DAB2 interacting protein

increases methylation

ISO

Methapyrilene results in increased methylation of DAB2IP intron

NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730

G

dishevelled-binding antagonist of beta-catenin 2

increases methylation
affects methylation

ISO

Methapyrilene results in increased methylation of DACT2 exon
Methapyrilene affects the methylation of DACT2 intron

NCBI chr 1:63,854,182...63,864,153
Ensembl chr 1:63,854,182...63,864,255

G

dystroglycan 1

increases methylation
decreases expression
decreases methylation

ISO
EXP

Methapyrilene results in increased methylation of DAG1 promoter
Methapyrilene results in decreased expression of DAG1 mRNA
Methapyrilene results in decreased methylation of DAG1 exon

PMID:30157460 PMID:30467583

NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199

G

D-amino-acid oxidase

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of DAO mRNA
Methapyrilene results in increased methylation of DAO intron

PMID:16393664 PMID:30157460 PMID:30467583

NCBI chr12:48,252,900...48,275,964
Ensembl chr12:48,252,902...48,273,300

G

death associated protein kinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of DAPK1 mRNA

NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581

G

death-associated protein kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of DAPK2 intron

NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:75,601,634...75,720,617

G

death-associated protein kinase 3

decreases expression

EXP

Methapyrilene results in decreased expression of DAPK3 mRNA

NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:9,174,904...9,183,272

G

aspartyl-tRNA synthetase 1

decreases expression

EXP

Methapyrilene results in decreased expression of DARS1 mRNA

NCBI chr13:42,410,351...42,465,467
Ensembl chr13:42,379,162...42,465,467

G

dynein assembly factor with WD repeats 1

increases methylation

ISO

Methapyrilene results in increased methylation of DAW1 intron

NCBI chr 9:91,883,656...91,920,733
Ensembl chr 9:91,881,067...91,921,349

G

diazepam binding inhibitor

increases expression

EXP

Methapyrilene results in increased expression of DBI mRNA

NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450

G

drebrin 1

increases methylation

ISO

Methapyrilene results in increased methylation of DBN1 exon

NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122

G

D-box binding PAR bZIP transcription factor

increases methylation

ISO

Methapyrilene results in increased methylation of DBP intron

NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205

G

dihydrolipoamide branched chain transacylase E2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of DBT mRNA
Methapyrilene results in increased methylation of DBT intron

PMID:30157460 PMID:30467583

NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525

G

DDB1 and CUL4 associated factor 11

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of DCAF11 mRNA
Methapyrilene results in decreased methylation of DCAF11 exon

PMID:30157460 PMID:30467583

NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672

G

DDB1 and CUL4 associated factor 4

increases methylation

ISO

Methapyrilene results in increased methylation of DCAF4 intron

NCBI chr 6:108,885,970...108,912,116
Ensembl chr 6:108,885,932...108,912,110

G

dephospho-CoA kinase domain containing

decreases methylation

ISO

Methapyrilene results in decreased methylation of DCAKD intron

NCBI chr10:88,457,829...88,489,011
Ensembl chr10:88,457,829...88,480,118

G

doublecortin domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of DCDC2 intron

NCBI chr17:40,274,009...40,459,757
Ensembl chr17:40,274,009...40,458,790

G

dachsous cadherin-related 2

increases methylation

ISO

Methapyrilene results in increased methylation of DCHS2 intron

NCBI chr 2:170,775,818...170,983,844
Ensembl chr 2:170,776,682...170,981,770

G

doublecortin-like kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of DCLK2 intron

NCBI chr 2:174,506,660...174,636,353
Ensembl chr 2:174,506,660...174,636,192

G

decapping enzyme, scavenger

decreases methylation

ISO

Methapyrilene results in decreased methylation of DCPS intron

NCBI chr 8:41,729,507...41,782,222
Ensembl chr 8:41,724,563...41,782,222

G

dynactin subunit 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of DCTN4 intron

NCBI chr18:56,251,187...56,279,844
Ensembl chr18:56,252,780...56,279,842

G

defective in cullin neddylation 1 domain containing 4

decreases expression

EXP

Methapyrilene results in decreased expression of DCUN1D4 mRNA

NCBI chr14:35,006,792...35,087,285
Ensembl chr14:35,006,792...35,088,520

G

dimethylarginine dimethylaminohydrolase 1

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of DDAH1 mRNA
Methapyrilene results in decreased expression of DDAH1 mRNA

PMID:15890375 PMID:30467583

NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626

G

DNA damage inducible 1 homolog 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of DDI2 intron

NCBI chr 5:159,272,625...159,318,365
Ensembl chr 5:159,272,625...159,318,310

G

DNA-damage inducible transcript 3

increases expression

EXP
ISO

Methapyrilene results in increased expression of DDIT3 mRNA

PMID:15120968 PMID:17450226 PMID:28935588 PMID:30467583

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DNA-damage-inducible transcript 4

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of DDIT4 mRNA
Methapyrilene results in decreased expression of DDIT4 mRNA

PMID:22484513 PMID:30467583

NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037

G

DNA-damage-inducible transcript 4-like

increases expression

EXP

Methapyrilene results in increased expression of DDIT4L mRNA

NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225

G

DEAD/H-box helicase 11

decreases methylation

ISO

Methapyrilene results in decreased methylation of DDX11 intron

NCBI chr 9:113,204,886...113,309,692
Ensembl chr 9:113,276,985...113,316,152

G

DEAD-box helicase 17

decreases expression

EXP

Methapyrilene results in decreased expression of DDX17 mRNA

NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747

G

DEAD-box helicase 20

increases methylation

ISO

Methapyrilene results in increased methylation of DDX20 intron

NCBI chr 2:195,847,105...195,859,989
Ensembl chr 2:195,847,105...195,855,461

G

DExD-box helicase 21

increases expression

EXP

Methapyrilene results in increased expression of DDX21 mRNA

NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238

G

DExD-box helicase 39A

increases expression

EXP

Methapyrilene results in increased expression of DDX39A mRNA

PMID:18619722 PMID:28935588

NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306

G

DEAD-box helicase 41

increases methylation

ISO

Methapyrilene results in increased methylation of DDX41 intron

NCBI chr17:9,108,030...9,113,562
Ensembl chr17:9,108,074...9,113,561

G

DEAD-box helicase 46

decreases expression

EXP

Methapyrilene results in decreased expression of DDX46 mRNA

NCBI chr17:8,947,237...8,993,705
Ensembl chr17:8,947,237...8,990,247

G

2,4-dienoyl-CoA reductase 1

decreases expression

EXP

Methapyrilene results in decreased expression of DECR1 mRNA

PMID:16393664 PMID:30467583

NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033

G

2,4-dienoyl-CoA reductase 2

decreases expression

EXP

Methapyrilene results in decreased expression of DECR2 mRNA

NCBI chr10:15,609,389...15,617,779
Ensembl chr10:15,611,092...15,617,397

G

differentially expressed in FDCP 8 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of DEF8 3' UTR

NCBI chr19:68,383,293...68,404,133
Ensembl chr19:68,383,349...68,404,125

G

DENN domain containing 1A

increases methylation

ISO

Methapyrilene results in increased methylation of DENND1A 3' UTR

NCBI chr 3:41,974,502...42,461,816
Ensembl chr 3:41,974,502...42,461,886

G

DENN domain containing 2B

decreases methylation

ISO

Methapyrilene results in decreased methylation of DENND2B intron

NCBI chr 1:172,978,895...173,129,623
Ensembl chr 1:172,978,895...173,129,810

G

DEP domain containing 1

decreases expression

ISO

Methapyrilene results in decreased expression of DEPDC1 mRNA

NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709

G

DEP domain containing 5, GATOR1 subcomplex subunit

increases methylation

ISO

Methapyrilene results in increased methylation of DEPDC5 intron

NCBI chr14:81,956,777...82,087,392
Ensembl chr14:81,956,777...82,087,246

G

DEP domain containing 7

increases expression

EXP

Methapyrilene results in increased expression of DEPDC7 mRNA

NCBI chr 3:111,554,701...111,575,979
Ensembl chr 3:111,554,706...111,575,979

G

DEP domain containing MTOR-interacting protein

increases methylation

ISO

Methapyrilene results in increased methylation of DEPTOR intron

NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041

G

derlin 1

decreases expression

EXP

Methapyrilene results in decreased expression of DERL1 mRNA

NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678

G

DET1 partner of COP1 E3 ubiquitin ligase

increases methylation

ISO

Methapyrilene results in increased methylation of DET1 exon

NCBI chr 1:142,159,120...142,175,366
Ensembl chr 1:142,127,876...142,175,336

G

DiGeorge syndrome critical region gene 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of DGCR2 intron

NCBI chr11:96,598,247...96,648,791
Ensembl chr11:96,597,197...96,648,786

G

diacylglycerol kinase, gamma

increases methylation

ISO

Methapyrilene results in increased methylation of DGKG intron

NCBI chr11:91,888,957...92,083,715
Ensembl chr11:91,888,782...92,082,105

G

diacylglycerol kinase, iota

increases methylation

ISO

Methapyrilene results in increased methylation of DGKI intron

NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832

G

diacylglycerol kinase zeta

decreases methylation

ISO

Methapyrilene results in decreased methylation of DGKZ intron

NCBI chr 3:98,359,804...98,401,847
Ensembl chr 3:98,359,804...98,401,951

G

dehydrodolichyl diphosphate synthase subunit

decreases expression

EXP

Methapyrilene results in decreased expression of DHDDS mRNA

NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:151,481,429...151,508,129

G

dihydrofolate reductase

increases methylation

ISO

Methapyrilene results in increased methylation of DHFR intron

NCBI chr 2:25,320,895...25,346,004

G

dehydrogenase/reductase 4

decreases expression

EXP

Methapyrilene results in decreased expression of DHRS4 mRNA

NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101

G

dehydrogenase E1 and transketolase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of DHTKD1 mRNA

NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071

G

DExH-box helicase 30

decreases methylation

ISO

Methapyrilene results in decreased methylation of DHX30 intron

NCBI chr 8:118,943,186...118,975,319
Ensembl chr 8:118,943,187...118,975,592

G

DEAH-box helicase 32 (putative)

decreases expression

EXP

Methapyrilene results in decreased expression of DHX32 mRNA

NCBI chr 1:197,954,503...198,013,779
Ensembl chr 1:197,954,503...198,007,489

G

DEAH-box helicase 35

increases methylation

ISO

Methapyrilene results in increased methylation of DHX35 intron

NCBI chr 3:167,869,971...167,927,300
Ensembl chr 3:167,870,055...167,927,300

G

DEAH-box helicase 36

decreases expression

EXP

Methapyrilene results in decreased expression of DHX36 mRNA

NCBI chr 2:149,006,089...149,044,192
Ensembl chr 2:149,006,089...149,044,191

G

DEAH-box helicase 37

increases methylation

ISO

Methapyrilene results in increased methylation of DHX37 intron

NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240

G

DEAH-box helicase 8

increases methylation

ISO

Methapyrilene results in increased methylation of DHX8 intron

NCBI chr10:87,167,861...87,204,426
Ensembl chr10:87,168,062...87,205,875

G

diaphanous-related formin 2

affects methylation

ISO

Methapyrilene affects the methylation of DIAPH2 intron

NCBI chr X:96,700,535...97,528,080
Ensembl chr X:96,700,726...97,528,080

G

diaphanous-related formin 3

decreases expression

EXP

Methapyrilene results in decreased expression of DIAPH3 mRNA

NCBI chr15:68,951,992...69,421,623
Ensembl chr15:68,951,989...69,421,552

G

death inducer-obliterator 1

increases methylation

ISO

Methapyrilene results in increased methylation of DIDO1 intron

NCBI chr 3:188,150,100...188,203,445
Ensembl chr 3:188,150,100...188,194,823

G

disco-interacting protein 2 homolog C

increases methylation

ISO

Methapyrilene results in increased methylation of DIP2C intron

NCBI chr17:65,338,711...65,724,111
Ensembl chr17:65,338,711...65,723,344

G

DIRAS family GTPase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of DIRAS1 intron

NCBI chr 7:9,338,660...9,343,524
Ensembl chr 7:9,327,335...9,347,881

G

dispatched RND transporter family member 3

increases methylation

ISO

Methapyrilene results in increased methylation of DISP3 intron

NCBI chr 5:163,955,160...164,003,980
Ensembl chr 5:163,955,160...164,003,950

G

dyskerin pseudouridine synthase 1

increases expression

EXP

Methapyrilene results in increased expression of DKC1 mRNA

NCBI chr  X:157,751,651...157,757,796
Ensembl chr  Y:380,743...385,405
Ensembl chr  X:380,743...385,405

G

dihydrolipoamide S-acetyltransferase

decreases expression

EXP

Methapyrilene results in decreased expression of DLAT protein

NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:59,868,214...59,900,818
Ensembl chr 1:59,868,214...59,900,818

G

discs large MAGUK scaffold protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of DLG1 mRNA

NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797

G

discs large MAGUK scaffold protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of DLG2 intron

NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215

G

discs large MAGUK scaffold protein 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of DLG5 intron

NCBI chr15:125,287...237,334
Ensembl chr15:125,290...237,332

G

DLG associated protein 1

affects methylation

ISO

Methapyrilene affects the methylation of DLGAP1 intron

NCBI chr 9:117,304,144...118,173,463
Ensembl chr 9:117,614,061...118,173,463

G

DLG associated protein 2

affects methylation

ISO

Methapyrilene affects the methylation of DLGAP2 intron

NCBI chr16:81,489,059...82,198,693
Ensembl chr16:81,494,649...82,198,684

G

DLG associated protein 4

affects methylation

ISO

Methapyrilene affects the methylation of DLGAP4 intron

NCBI chr 3:165,584,271...165,731,868
Ensembl chr 3:165,584,360...165,730,604

G

DLG associated protein 5

increases methylation

ISO

Methapyrilene results in increased methylation of DLGAP5 intron

NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176

G

delta like non-canonical Notch ligand 1

increases methylation

ISO

Methapyrilene results in increased methylation of DLK1 polyA tail

NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529

G

delta like canonical Notch ligand 4

increases methylation

ISO

Methapyrilene results in increased methylation of DLL4 3' UTR

NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:126,770,794...126,780,763

G

deleted in malignant brain tumors 1

increases methylation

ISO

Methapyrilene results in increased methylation of DMBT1 intron

NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:195,047,713...195,126,704

G

dimethylglycine dehydrogenase

increases expression

EXP

Methapyrilene results in increased expression of DMGDH protein

NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071

G

Dmx-like 2

decreases expression

EXP

Methapyrilene results in decreased expression of DMXL2 mRNA

NCBI chr 8:63,637,314...63,803,911
Ensembl chr 8:63,637,314...63,781,116

G

dynein axonemal assembly factor 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of DNAAF9 intron

NCBI chr 3:138,370,971...138,505,711
Ensembl chr 3:138,372,531...138,505,695

G

dynein, axonemal, heavy chain 1

affects methylation
decreases methylation

ISO

Methapyrilene affects the methylation of DNAH1 intron
Methapyrilene results in decreased methylation of DNAH1 exon

NCBI chr16:6,462,419...6,523,545
Ensembl chr16:6,462,419...6,524,760

G

dynein, axonemal, heavy chain 10

decreases methylation

ISO

Methapyrilene results in decreased methylation of DNAH10 intron

NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860

G

dynein axonemal heavy chain 14

increases methylation

ISO

Methapyrilene results in increased methylation of DNAH14 intron

NCBI chr13:95,853,735...96,070,327
Ensembl chr13:95,854,534...96,070,330

G

dynein, axonemal, heavy chain 2

increases methylation

ISO

Methapyrilene results in increased methylation of DNAH2 intron

NCBI chr10:54,641,450...54,766,502
Ensembl chr10:54,641,450...54,766,026

G

dynein, axonemal, heavy chain 8

affects methylation

ISO

Methapyrilene affects the methylation of DNAH8 intron

NCBI chr20:8,694,371...8,948,849
Ensembl chr20:8,694,398...8,948,849

G

dynein, axonemal, heavy chain 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of DNAH9 intron

NCBI chr10:50,996,796...51,363,977
Ensembl chr10:50,996,796...51,363,963

G

dynein, axonemal, intermediate chain 2

increases methylation

ISO

Methapyrilene results in increased methylation of DNAI2 intron

NCBI chr10:100,259,022...100,292,427
Ensembl chr10:100,258,994...100,292,426

G

dynein axonemal intermediate chain 7

increases methylation

ISO

Methapyrilene results in increased methylation of DNAI7 intron

NCBI chr 4:179,874,338...179,910,716
Ensembl chr 4:179,873,522...179,910,780

G

DnaJ heat shock protein family (Hsp40) member A1

increases methylation

ISO

Methapyrilene results in increased methylation of DNAJA1 intron

NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160

G

DnaJ heat shock protein family (Hsp40) member B13

increases methylation

ISO

Methapyrilene results in increased methylation of DNAJB13 intron

NCBI chr 1:164,260,716...164,275,172
Ensembl chr 1:164,260,724...164,275,093

G

DnaJ heat shock protein family (Hsp40) member B6

increases methylation

ISO

Methapyrilene results in increased methylation of DNAJB6 intron

NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:6,128,070...6,232,005

G

DnaJ heat shock protein family (Hsp40) member C14

decreases expression

EXP

Methapyrilene results in decreased expression of DNAJC14 mRNA

NCBI chr 7:1,818,360...1,831,642
Ensembl chr 7:1,820,247...1,831,658

G

DnaJ heat shock protein family (Hsp40) member C3

increases expression

EXP

Methapyrilene results in increased expression of DNAJC3 mRNA

NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643

G

DnaJ heat shock protein family (Hsp40) member C5

decreases methylation

ISO

Methapyrilene results in decreased methylation of DNAJC5 intron

NCBI chr 3:188,999,508...189,033,455
Ensembl chr 3:188,999,470...189,034,089

G

DnaJ heat shock protein family (Hsp40) member C7

increases methylation

ISO

Methapyrilene results in increased methylation of DNAJC7 intron

NCBI chr10:86,018,977...86,055,419
Ensembl chr10:86,018,961...86,055,489

G

dynamin 3

increases methylation

ISO

Methapyrilene results in increased methylation of DNM3 intron

NCBI chr13:76,892,381...77,371,346
Ensembl chr13:76,892,171...77,371,350

G

dynamin binding protein

decreases expression

EXP

Methapyrilene results in decreased expression of DNMBP mRNA

NCBI chr 1:252,685,406...252,778,642
Ensembl chr 1:252,685,406...252,778,688

G

double C2 domain alpha

decreases methylation

ISO

Methapyrilene results in decreased methylation of DOC2A exon

NCBI chr 1:190,887,306...190,893,057
Ensembl chr 1:190,888,214...190,893,384

G

double C2 domain beta

increases methylation

ISO

Methapyrilene results in increased methylation of DOC2B intron

NCBI chr10:61,126,295...61,151,533
Ensembl chr10:61,126,295...61,151,533

G

dedicator of cytokinesis 10

increases methylation

ISO

Methapyrilene results in increased methylation of DOCK10 intron

NCBI chr 9:89,291,936...89,549,871
Ensembl chr 9:89,291,800...89,549,973

G

dedicator of cytokinesis 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of DOCK4 intron

NCBI chr 6:63,240,050...63,629,772
Ensembl chr 6:63,240,136...63,629,772

G

dedicator of cytokinesis 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of DOCK5 exon

NCBI chr15:46,155,124...46,334,127
Ensembl chr15:46,155,125...46,334,042

G

dedicator of cytokinesis 7

decreases expression

EXP

Methapyrilene results in decreased expression of DOCK7 mRNA

NCBI chr 5:118,714,863...118,898,362
Ensembl chr 5:118,714,863...118,898,335

G

dedicator of cytokinesis 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of DOCK8 intron

NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:232,075,588...232,268,833

G

dedicator of cytokinesis 9

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of DOCK9 intron
Methapyrilene results in decreased expression of DOCK9 mRNA

PMID:30157460 PMID:30467583

NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799

G

dolichol kinase

decreases expression

EXP

Methapyrilene results in decreased expression of DOLK mRNA

NCBI chr 3:33,955,642...33,957,680
Ensembl chr 3:33,954,308...33,958,365

G

DNA replication fork stabilization factor DONSON

decreases methylation

ISO

Methapyrilene results in decreased methylation of DONSON intron

NCBI chr11:44,405,794...44,419,099
Ensembl chr11:44,405,804...44,418,791

G

DOP1 leucine zipper like protein B

decreases methylation

ISO

Methapyrilene results in decreased methylation of DOP1B intron

NCBI chr11:46,494,058...46,595,601
Ensembl chr11:46,494,058...46,595,601

G

deleted in primary ciliary dyskinesia

decreases methylation

ISO

Methapyrilene results in decreased methylation of DPCD 3' UTR

NCBI chr 1:254,357,755...254,375,918
Ensembl chr 1:254,357,778...254,375,918

G

double PHD fingers 1

affects methylation

ISO

Methapyrilene affects the methylation of DPF1 intron

NCBI chr 1:93,729,683...93,743,425
Ensembl chr 1:93,726,970...93,743,425

G

double PHD fingers 3

affects methylation

ISO

Methapyrilene affects the methylation of DPF3 intron

NCBI chr 6:108,577,792...108,856,724
Ensembl chr 6:108,577,183...108,856,798

G

diphthamine biosynthesis 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of DPH6 intron

NCBI chr 3:121,761,495...121,891,727
Ensembl chr 3:121,676,141...121,891,658

G

dipeptidyl peptidase like 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of DPP6 intron

NCBI chr 4:8,323,220...9,242,694
Ensembl chr 4:8,324,843...9,242,209

G

dipeptidylpeptidase 8

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of DPP8 mRNA
Methapyrilene results in decreased methylation of DPP8 intron

PMID:30157460 PMID:30467583

NCBI chr 8:74,445,815...74,501,017
Ensembl chr 8:74,445,835...74,501,017

G

dipeptidyl peptidase 9

increases methylation

ISO

Methapyrilene results in increased methylation of DPP9 intron

NCBI chr 9:1,098,505...1,133,500
Ensembl chr 9:1,095,929...1,177,715

G

dermatopontin

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of DPT mRNA
Methapyrilene results in increased methylation of DPT intron

PMID:30157460 PMID:30467583

NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758

G

dpy-19 like C-mannosyltransferase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of DPY19L3 intron

NCBI chr 1:97,487,206...97,554,232
Ensembl chr 1:97,487,206...97,554,232

G

dihydropyrimidine dehydrogenase

decreases expression

EXP

Methapyrilene results in decreased expression of DPYD mRNA

PMID:15890375 PMID:30467583

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778

G

dihydropyrimidinase-like 2

increases methylation

ISO

Methapyrilene results in increased methylation of DPYSL2 intron

NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065

G

dihydropyrimidinase-like 3

increases methylation

ISO

Methapyrilene results in increased methylation of DPYSL3 intron

NCBI chr18:35,625,357...35,731,152
Ensembl chr18:35,625,357...35,731,152

G

DNA damage regulated autophagy modulator 2

decreases expression

EXP

Methapyrilene results in decreased expression of DRAM2 mRNA

NCBI chr 2:196,724,052...196,752,645
Ensembl chr 2:196,723,858...196,755,103

G

dorsal inhibitory axon guidance protein

increases methylation

ISO

Methapyrilene results in increased methylation of DRAXIN intron

NCBI chr 5:163,813,308...163,846,609
Ensembl chr 5:163,816,502...163,855,174

G

desmocollin 3

increases methylation

ISO

Methapyrilene results in increased methylation of DSC3 intron

NCBI chr18:11,654,833...11,688,871
Ensembl chr18:11,653,832...11,688,871

G

DS cell adhesion molecule

increases methylation

ISO

Methapyrilene results in increased methylation of DSCAM intron

NCBI chr11:49,391,385...49,976,861
Ensembl chr11:49,347,531...49,976,238

G

DS cell adhesion molecule-like 1

increases methylation

ISO

Methapyrilene results in increased methylation of DSCAML1 exon; Methapyrilene results in increased methylation of DSCAML1 intron

NCBI chr 8:54,637,054...54,954,042
Ensembl chr 8:54,636,932...54,954,040

G

desmoglein 2

decreases expression

EXP

Methapyrilene results in decreased expression of DSG2 mRNA

NCBI chr18:12,121,287...12,179,590
Ensembl chr18:12,121,181...12,179,590

G

dual serine/threonine and tyrosine protein kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of DSTYK 3' UTR

NCBI chr13:46,409,412...46,457,426
Ensembl chr13:46,409,412...46,457,424

G

D-aminoacyl-tRNA deacylase 2

increases methylation

ISO

Methapyrilene results in increased methylation of DTD2 intron

NCBI chr 6:75,185,496...75,191,774
Ensembl chr 6:75,156,201...75,191,774

G

dystrobrevin, alpha

decreases methylation

ISO

Methapyrilene results in decreased methylation of DTNA intron

NCBI chr18:14,862,801...15,218,993
Ensembl chr18:14,862,818...15,218,993

G

DTW domain containing 2

decreases expression

EXP

Methapyrilene results in decreased expression of DTWD2 mRNA

NCBI chr18:45,003,242...45,088,595
Ensembl chr18:45,003,644...45,088,419

G

deltex E3 ubiquitin ligase 3L

decreases expression

EXP

Methapyrilene results in decreased expression of DTX3L mRNA

NCBI chr11:78,320,225...78,329,837
Ensembl chr11:78,317,650...78,329,837

G

dual oxidase 1

increases expression

ISO

Methapyrilene results in increased expression of DUOX1 mRNA

NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187

G

dual specificity phosphatase 13B

increases expression

ISO

Methapyrilene results in increased expression of DUSP13B mRNA

NCBI chr15:2,616,761...2,624,434
Ensembl chr15:2,609,049...2,624,887

G

dual specificity phosphatase 22

affects methylation

ISO

Methapyrilene affects the methylation of DUSP22 intron

NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895

G

dual specificity phosphatase 4

increases methylation

ISO

Methapyrilene results in increased methylation of DUSP4 intron

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700

G

dual specificity phosphatase 5

increases methylation

ISO

Methapyrilene results in increased methylation of DUSP5 promoter

NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417

G

dual specificity phosphatase 6

decreases expression
increases expression

EXP

Methapyrilene results in decreased expression of DUSP6 mRNA
Methapyrilene results in increased expression of DUSP6 mRNA

PMID:15890375 PMID:30467583

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

deoxyuridine triphosphatase

increases expression

EXP

Methapyrilene results in increased expression of DUT mRNA

NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956

G

DPY30 domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of DYDC2 promoter

NCBI chr16:16,962,273...16,976,034
Ensembl chr16:16,962,290...16,970,258

G

dymeclin

increases methylation

ISO

Methapyrilene results in increased methylation of DYM intron

NCBI chr18:70,879,835...71,176,006
Ensembl chr18:70,880,255...71,176,004

G

dynein cytoplasmic 1 heavy chain 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of DYNC1H1 intron

NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116

G

dynein, cytoplasmic 1 light intermediate chain 2

decreases expression

EXP

Methapyrilene results in decreased expression of DYNC1LI2 mRNA

NCBI chr19:538,207...561,110
Ensembl chr19:538,211...561,107

G

dynein cytoplasmic 2 heavy chain 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of DYNC2H1 intron

NCBI chr 8:12,473,955...12,697,075
Ensembl chr 8:12,473,955...12,697,058

G

dynein 2 intermediate chain 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of DYNC2I2 intron

NCBI chr 3:33,703,882...33,719,960
Ensembl chr 3:33,703,882...33,719,960

G

dynein light chain LC8-type 1

increases expression

EXP

Methapyrilene results in increased expression of DYNLL1 mRNA

NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861

G

dynein light chain LC8-type 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of DYNLL2 promoter

NCBI chr10:73,264,260...73,283,042
Ensembl chr10:73,264,261...73,272,285

G

dual specificity tyrosine phosphorylation regulated kinase 2

decreases expression

EXP

Methapyrilene results in decreased expression of DYRK2 mRNA

NCBI chr 7:56,235,276...56,265,741
Ensembl chr 7:56,235,276...56,265,942

G

dysferlin

increases methylation

ISO

Methapyrilene results in increased methylation of DYSF intron

NCBI chr 4:118,048,460...118,248,273
Ensembl chr 4:118,047,989...118,248,273

G

double zinc ribbon and ankyrin repeat domains 1

increases methylation

ISO

Methapyrilene results in increased methylation of DZANK1 intron

NCBI chr 3:152,309,228...152,361,548
Ensembl chr 3:152,309,228...152,361,548

G

DAZ interacting zinc finger protein 1-like

increases methylation

ISO

Methapyrilene results in increased methylation of DZIP1L intron

NCBI chr 8:109,067,466...109,108,390
Ensembl chr 8:109,067,775...109,108,393

G

E2F transcription factor 4

increases methylation

ISO

Methapyrilene results in increased methylation of E2F4 exon

NCBI chr19:50,084,335...50,091,731
Ensembl chr19:50,084,335...50,091,834

G

glutamyl-tRNA synthetase 2, mitochondrial

decreases expression

EXP

Methapyrilene results in decreased expression of EARS2 mRNA

NCBI chr 1:186,025,740...186,057,165

G

estrogen receptor binding site associated antigen 9

decreases expression

EXP

Methapyrilene results in decreased expression of EBAG9 mRNA

NCBI chr 7:77,695,213...77,713,565
Ensembl chr 7:77,695,072...77,713,557

G

EBF transcription factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of EBF3 intron

NCBI chr 1:201,426,446...201,544,444
Ensembl chr 1:201,426,450...201,544,305

G

endothelin converting enzyme 1

decreases expression

EXP

Methapyrilene results in decreased expression of ECE1 mRNA

NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719

G

enoyl-CoA hydratase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ECH1 mRNA

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440

G

enoyl CoA hydratase domain containing 3

decreases expression

EXP

Methapyrilene results in decreased expression of ECHDC3 mRNA

NCBI chr17:76,980,112...77,002,934
Ensembl chr17:76,980,083...77,002,934

G

enoyl-CoA hydratase, short chain 1

increases expression

EXP

Methapyrilene results in increased expression of ECHS1 protein

NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506

G

enoyl-CoA delta isomerase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ECI1 mRNA

NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773

G

enoyl-Coenzyme A delta isomerase 3

decreases expression

EXP

Methapyrilene results in decreased expression of ECI3 mRNA

NCBI chr17:30,127,425...30,149,249
Ensembl chr17:30,128,588...30,149,137

G

ectodysplasin-A receptor

increases methylation

ISO

Methapyrilene results in increased methylation of EDAR exon

NCBI chr20:27,130,934...27,209,672
Ensembl chr20:27,130,934...27,209,630

G

enhancer of mRNA decapping 3

decreases expression

EXP

Methapyrilene results in decreased expression of EDC3 mRNA

NCBI chr 8:67,002,032...67,047,563
Ensembl chr 8:67,002,014...67,047,559

G

ER degradation enhancing alpha-mannosidase like protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of EDEM1 mRNA

NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060

G

ER degradation enhancing alpha-mannosidase like protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of EDEM2 intron

NCBI chr 3:164,661,741...164,687,559
Ensembl chr 3:164,661,742...164,687,559

G

ER degradation enhancing alpha-mannosidase like protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of EDEM3 mRNA

NCBI chr13:66,403,022...66,470,496
Ensembl chr13:66,408,590...66,472,270

G

endothelial differentiation-related factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of EDF1 polyA tail

NCBI chr 3:28,764,906...28,779,499

G

EGF like repeats and discoidin domains 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of EDIL3 intron

NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379

G

embryonic ectoderm development

increases expression

EXP

Methapyrilene results in increased expression of EED mRNA

NCBI chr 1:153,280,419...153,307,537
Ensembl chr 1:153,280,422...153,307,500

G

eukaryotic translation elongation factor 1 alpha 2

increases methylation

ISO

Methapyrilene results in increased methylation of EEF1A2 intron

NCBI chr 3:188,643,455...188,652,633
Ensembl chr 3:188,643,458...188,677,712

G

eukaryotic translation elongation factor 1 gamma

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of EEF1G mRNA
Methapyrilene results in decreased expression of EEF1G protein

PMID:15890375 PMID:30467583

NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479

G

eukaryotic translation elongation factor 2

increases expression

EXP

Methapyrilene results in increased expression of EEF2 mRNA

NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544

G

eukaryotic elongation factor-2 kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of EEF2K intron

NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:184,824,420...184,888,048

G

EF-hand calcium binding domain 6

affects methylation

ISO

Methapyrilene affects the methylation of EFCAB6 intron

NCBI chr 7:116,899,022...117,085,998
Ensembl chr 7:116,899,022...117,075,827

G

EF-hand domain family, member D1

decreases methylation

ISO

Methapyrilene results in decreased methylation of EFHD1 intron

NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798

G

ephrin A2

decreases methylation

ISO

Methapyrilene results in decreased methylation of EFNA2 intron

NCBI chr 7:10,167,091...10,177,719
Ensembl chr 7:10,167,091...10,177,719

G

EFR3 homolog A

decreases expression

EXP

Methapyrilene results in decreased expression of EFR3A mRNA

NCBI chr 7:99,441,764...99,522,454
Ensembl chr 7:99,441,767...99,522,454

G

EFR3 homolog B

increases methylation

ISO

Methapyrilene results in increased methylation of EFR3B intron

NCBI chr 6:32,664,593...32,740,417
Ensembl chr 6:32,666,945...32,740,417

G

EGF-like-domain, multiple 7

increases methylation

ISO

Methapyrilene results in increased methylation of EGFL7 intron

NCBI chr 3:29,802,481...29,814,966
Ensembl chr 3:29,802,690...29,814,951

G

epidermal growth factor receptor

decreases expression

EXP

Methapyrilene results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

EH domain binding protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of EHBP1 mRNA

NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579

G

EH domain binding protein 1-like 1

increases methylation

ISO

Methapyrilene results in increased methylation of EHBP1L1 exon

NCBI chr 1:212,423,444...212,444,357
Ensembl chr 1:212,423,447...212,443,598

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

decreases expression

EXP

Methapyrilene results in decreased expression of EHHADH mRNA

NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662

G

euchromatic histone lysine methyltransferase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of EHMT1 intron

NCBI chr 3:27,978,888...28,127,178
Ensembl chr 3:27,978,888...28,127,349

G

EP300 interacting inhibitor of differentiation 1

decreases expression

EXP

Methapyrilene results in decreased expression of EID1 mRNA

NCBI chr 3:133,376,389...133,378,108
Ensembl chr 3:133,370,474...133,378,434

G

eukaryotic translation initiation factor 1A, X-linked

decreases expression

EXP

Methapyrilene results in decreased expression of EIF1AX mRNA

NCBI chr X:39,307,320...39,322,023
Ensembl chr X:39,307,137...39,322,021

G

eukaryotic translation initiation factor 2-alpha kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of EIF2AK2 intron

NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116

G

eukaryotic translation initiation factor 2 alpha kinase 3

decreases expression

EXP

Methapyrilene results in decreased expression of EIF2AK3 mRNA

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268

G

eukaryotic translation initiation factor 2B subunit gamma

increases methylation

ISO

Methapyrilene results in increased methylation of EIF2B3 intron

NCBI chr 5:135,728,764...135,795,276
Ensembl chr 5:135,728,959...135,799,914

G

eukaryotic translation initiation factor 2 subunit alpha

increases expression

EXP

Methapyrilene results in increased expression of EIF2S1 mRNA

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649

G

eukaryotic translation initiation factor 4E

increases expression

EXP

Methapyrilene results in increased expression of EIF4E mRNA

NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

EXP

Methapyrilene results in increased expression of EIF4EBP1 mRNA

NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874

G

eukaryotic translation initiation factor 4E binding protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of EIF4EBP3 mRNA

NCBI chr18:28,540,324...28,542,070
Ensembl chr18:28,540,058...28,542,061

G

eukaryotic translation initiation factor 4 gamma, 3

decreases methylation
decreases expression

EXP

Methapyrilene results in decreased methylation of EIF4G3 gene
Methapyrilene results in decreased expression of EIF4G3 mRNA

PMID:26431795 PMID:30467583

NCBI chr 5:155,481,378...155,702,194
Ensembl chr 5:155,481,378...155,702,194

G

EARP complex and GARP complex interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of EIPR1 intron

NCBI chr 6:51,116,827...51,230,453
Ensembl chr 6:51,116,747...51,230,452

G

ELAV like RNA binding protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of ELAVL2 intron

NCBI chr 5:111,076,705...111,202,341
Ensembl chr 5:111,076,705...111,224,918

G

E74 like ETS transcription factor 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of ELF4 intron

NCBI chr X:132,465,290...132,508,175
Ensembl chr X:132,468,539...132,478,689

G

E74 like ETS transcription factor 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of ELF5 intron

NCBI chr 3:110,264,460...110,291,926
Ensembl chr 3:110,252,797...110,291,926

G

extracellular leucine-rich repeat and fibronectin type III domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of ELFN1 intron

NCBI chr12:19,773,911...19,839,375
Ensembl chr12:19,772,908...19,841,961

G

extracellular leucine-rich repeat and fibronectin type III domain containing 2

affects methylation

ISO

Methapyrilene affects the methylation of ELFN2 intron

NCBI chr 7:112,101,998...112,153,280
Ensembl chr 7:112,074,331...112,153,451

G

ETS transcription factor ELK4

decreases expression

EXP

Methapyrilene results in decreased expression of ELK4 mRNA

NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199

G

elongation factor for RNA polymerase II

increases methylation

ISO

Methapyrilene results in increased methylation of ELL intron

NCBI chr16:18,877,751...18,925,449
Ensembl chr16:18,877,751...18,925,076

G

engulfment and cell motility 3

decreases expression

EXP

Methapyrilene results in decreased expression of ELMO3 mRNA

NCBI chr19:50,091,883...50,096,324
Ensembl chr19:50,091,924...50,096,338

G

elongation factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of ELOF1 exon

NCBI chr 8:28,921,338...28,926,612
Ensembl chr 8:28,921,339...28,926,228

G

ELOVL fatty acid elongase 2

decreases expression

EXP

Methapyrilene results in decreased expression of ELOVL2 mRNA

NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601

G

elongator acetyltransferase complex subunit 2

decreases expression

EXP

Methapyrilene results in decreased expression of ELP2 mRNA

NCBI chr18:16,160,686...16,196,307
Ensembl chr18:16,160,671...16,196,414

G

ER membrane protein complex subunit 10

increases methylation

ISO

Methapyrilene results in increased methylation of EMC10 promoter

NCBI chr 1:104,119,040...104,125,409
Ensembl chr 1:104,119,040...104,125,368

G

elastin microfibril interfacer 2

affects methylation

ISO

Methapyrilene affects the methylation of EMILIN2 intron

NCBI chr 9:118,607,312...118,667,087
Ensembl chr 9:118,606,891...118,666,957

G

EMAP like 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of EML4 intron

NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439

G

epithelial membrane protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of EMP1 mRNA

NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365

G

ectodermal-neural cortex 1

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of ENC1 mRNA
Methapyrilene results in decreased expression of ENC1 mRNA

PMID:22484513 PMID:30467583

NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721

G

endonuclease V

decreases methylation

ISO

Methapyrilene results in decreased methylation of ENDOV polyA tail

NCBI chr10:105,258,540...105,276,209
Ensembl chr10:105,258,593...105,276,209

G

endoglin

increases methylation

ISO

Methapyrilene results in increased methylation of ENG intron

NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933

G

endo-beta-N-acetylglucosaminidase

increases methylation

ISO

Methapyrilene results in increased methylation of ENGASE 3' UTR

NCBI chr10:104,205,753...104,218,416
Ensembl chr10:104,205,752...104,218,411

G

glutamyl aminopeptidase

increases methylation

ISO

Methapyrilene results in increased methylation of ENPEP intron

NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of ENPP2 mRNA
Methapyrilene results in decreased methylation of ENPP2 intron

PMID:16393664 PMID:30157460

NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957

G

ectonucleotide pyrophosphatase/phosphodiesterase 3

decreases expression

EXP

Methapyrilene results in decreased expression of ENPP3 mRNA

NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:22,382,964...22,454,314

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of ENPP7 intron

NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,740,763...104,745,760

G

ectonucleoside triphosphate diphosphohydrolase 3

increases methylation

ISO

Methapyrilene results in increased methylation of ENTPD3 promoter

NCBI chr 8:129,124,540...129,155,528
Ensembl chr 8:129,124,709...129,156,252

G

endosomal transmembrane epsin interactor 1

increases methylation

ISO

Methapyrilene results in increased methylation of ENTREP1 intron

NCBI chr 1:231,018,987...231,073,474
Ensembl chr 1:231,018,987...231,102,708

G

E1A binding protein p400

increases methylation

ISO

Methapyrilene results in increased methylation of EP400 intron

NCBI chr12:51,551,665...51,658,635
Ensembl chr12:51,551,695...51,658,634

G

erythrocyte membrane protein band 4.1-like 1

increases methylation

ISO

Methapyrilene results in increased methylation of EPB41L1 intron

NCBI chr 3:165,389,295...165,512,821
Ensembl chr 3:165,389,293...165,510,498

G

erythrocyte membrane protein band 4.1 like 4B

increases methylation

ISO

Methapyrilene results in increased methylation of EPB41L4B intron

NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752

G

erythrocyte membrane protein band 4.1 like 5

decreases expression

EXP

Methapyrilene results in decreased expression of EPB41L5 mRNA

NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133

G

ectopic P-granules 5 autophagy tethering factor

increases methylation

ISO

Methapyrilene results in increased methylation of EPG5 intron

NCBI chr18:73,679,106...73,776,694
Ensembl chr18:73,679,116...73,776,677

G

Eph receptor A1

increases methylation

ISO

Methapyrilene results in increased methylation of EPHA1 exon

NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:72,213,037...72,227,474

G

EPH receptor A10

decreases methylation

ISO

Methapyrilene results in decreased methylation of EPHA10 intron

NCBI chr 5:142,424,260...142,460,305
Ensembl chr 5:142,424,296...142,460,305

G

Eph receptor A2

increases expression

EXP

Methapyrilene results in increased expression of EPHA2 mRNA

NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234

G

Eph receptor A8

increases methylation

ISO

Methapyrilene results in increased methylation of EPHA8 intron

NCBI chr 5:154,449,566...154,476,966
Ensembl chr 5:154,449,566...154,476,966

G

Eph receptor B2

increases methylation

ISO

Methapyrilene results in increased methylation of EPHB2 intron

NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:154,179,065...154,360,615

G

epoxide hydrolase 1

increases expression

EXP

Methapyrilene results in increased expression of EPHX1 mRNA

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

epoxide hydrolase 2

decreases expression

EXP

Methapyrilene results in decreased expression of EPHX2 mRNA

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

epsin 2

increases methylation

ISO

Methapyrilene results in increased methylation of EPN2 intron

NCBI chr10:46,697,238...46,759,128
Ensembl chr10:46,697,238...46,759,092

G

epiplakin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of EPPK1 exon

NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468

G

glutamyl-prolyl-tRNA synthetase 1

decreases expression

EXP

Methapyrilene results in decreased expression of EPRS1 mRNA

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509

G

epidermal growth factor receptor pathway substrate 15

decreases expression

EXP

Methapyrilene results in decreased expression of EPS15 mRNA

NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856

G

epidermal growth factor receptor pathway substrate 15-like 1

affects methylation

ISO

Methapyrilene affects the methylation of EPS15L1 intron

NCBI chr16:17,460,330...17,573,824
Ensembl chr16:17,460,465...17,535,703

G

EPS8 signaling adaptor L3

increases methylation

ISO

Methapyrilene results in increased methylation of EPS8L3 intron

NCBI chr 2:198,202,862...198,216,255
Ensembl chr 2:198,200,486...198,216,255

G

endoplasmic reticulum aminopeptidase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ERAP1 mRNA

NCBI chr 2:5,666,337...5,705,256
Ensembl chr 2:5,666,436...5,740,056

G

ELKS/RAB6-interacting/CAST family member 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ERC1 intron

NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:154,435,944...154,727,987

G

ELKS/RAB6-interacting/CAST family member 2

increases methylation

ISO

Methapyrilene results in increased methylation of ERC2 intron

NCBI chr16:2,819,399...3,680,258
Ensembl chr16:2,819,512...3,680,258

G

ERCC excision repair 5, endonuclease

decreases methylation

ISO

Methapyrilene results in decreased methylation of ERCC5 intron

NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084

G

ETS transcription factor ERG

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of ERG intron
Methapyrilene results in increased methylation of ERG 3' UTR

NCBI chr11:48,148,149...48,370,472
Ensembl chr11:48,148,153...48,370,688

G

ERI1 exoribonuclease family member 3

increases methylation

ISO

Methapyrilene results in increased methylation of ERI3 polyA tail

NCBI chr 5:136,252,691...136,379,832
Ensembl chr 5:136,252,683...136,379,815

G

ER lipid raft associated 1

decreases expression

EXP

Methapyrilene results in decreased expression of ERLIN1 mRNA

NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:252,870,356...252,905,947

G

ER lipid raft associated 2

decreases expression

EXP

Methapyrilene results in decreased expression of ERLIN2 mRNA

NCBI chr16:71,720,486...71,736,999
Ensembl chr16:71,721,364...71,736,503

G

ERBB receptor feedback inhibitor 1

decreases expression

EXP

Methapyrilene results in decreased expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432

G

espin

decreases methylation

ISO

Methapyrilene results in decreased methylation of ESPN intron

NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984

G

estrogen receptor 1

affects methylation

ISO

Methapyrilene affects the methylation of ESR1 intron

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

estrogen-related receptor gamma

decreases methylation

ISO

Methapyrilene results in decreased methylation of ESRRG intron

NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877

G

extended synaptotagmin 1

increases methylation

ISO

Methapyrilene results in increased methylation of ESYT1 intron

NCBI chr 7:1,513,381...1,530,836
Ensembl chr 7:1,513,381...1,530,732

G

electron transfer flavoprotein subunit alpha

increases methylation

ISO

Methapyrilene results in increased methylation of ETFA intron

NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:64,731,193...64,788,080

G

electron transfer flavoprotein subunit beta

increases expression

EXP

Methapyrilene results in increased expression of ETFB protein

NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659

G

electron transfer flavoprotein dehydrogenase

decreases expression

EXP

Methapyrilene results in decreased expression of ETFDH mRNA

NCBI chr 2:167,038,707...167,060,758
Ensembl chr 2:167,025,823...167,060,770

G

enhancer trap locus 4

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of KIAA1217 intron
Methapyrilene results in decreased expression of ETL4 mRNA

PMID:30157460 PMID:30467583

NCBI chr17:87,749,486...88,213,158
Ensembl chr17:87,403,819...88,213,158

G

ethanolamine kinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of ETNK1 mRNA

NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721

G

ETS proto-oncogene 2, transcription factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of ETS2 promoter

NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842

G

ETS variant transcription factor 6

affects methylation

ISO

Methapyrilene affects the methylation of ETV6 intron

NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:168,580,138...168,819,802

G

eva-1 homolog C

increases methylation

ISO

Methapyrilene results in increased methylation of EVA1C intron

NCBI chr11:43,575,613...43,649,677
Ensembl chr11:43,576,332...43,649,834

G

Enah/Vasp-like

increases methylation

ISO

Methapyrilene results in increased methylation of EVL polyA tail

NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:133,238,547...133,358,729

G

exocyst complex component 1

decreases expression

EXP

Methapyrilene results in decreased expression of EXOC1 mRNA

NCBI chr14:31,965,782...32,014,156
Ensembl chr14:31,965,782...32,014,127

G

exocyst complex component 2

decreases expression

EXP

Methapyrilene results in decreased expression of EXOC2 mRNA

NCBI chr17:33,714,949...33,906,901
Ensembl chr17:33,715,008...33,901,944

G

exo/endonuclease G

decreases methylation

ISO

Methapyrilene results in decreased methylation of EXOG intron

NCBI chr 8:128,062,688...128,082,529
Ensembl chr 8:128,059,126...128,083,460

G

exosome component 4

decreases expression

EXP

Methapyrilene results in decreased expression of EXOSC4 mRNA

NCBI chr 7:109,928,491...109,931,233
Ensembl chr 7:109,928,498...109,931,820

G

exosome component 5

decreases expression

EXP

Methapyrilene results in decreased expression of EXOSC5 mRNA

NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046

G

EYA transcriptional coactivator and phosphatase 1

increases methylation

ISO

Methapyrilene results in increased methylation of EYA1 intron

NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

decreases expression

EXP

Methapyrilene results in decreased expression of EZH1 mRNA

NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

increases methylation

ISO

Methapyrilene results in increased methylation of EZH2 intron

NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183

G

EZH inhibitory protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of EZHIP promoter

NCBI chr X:19,040,397...19,043,463
Ensembl chr X:19,040,777...19,044,071

G

coagulation factor X

decreases expression

ISO

Methapyrilene results in decreased expression of F10 mRNA

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280

G

coagulation factor V

decreases expression

EXP

Methapyrilene results in decreased expression of F5 mRNA

NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247

G

coagulation factor VII

increases methylation

ISO

Methapyrilene results in increased methylation of F7 intron; Methapyrilene results in increased methylation of F7 promoter

NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738

G

coagulation factor VIII

increases methylation

ISO

Methapyrilene results in increased methylation of F8 intron

NCBI chr18:155,237...187,186
Ensembl chr18:155,309...186,683

G

coagulation factor VIII-associated 1

decreases expression

EXP

Methapyrilene results in decreased expression of F8A1 mRNA

NCBI chr X:155,977,859...155,979,373
Ensembl chr X:155,976,941...156,108,974

G

FA core complex associated protein 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAAP20 intron

NCBI chr 5:171,083,328...171,097,599
Ensembl chr 5:171,087,847...171,097,599

G

fatty acid binding protein 1

decreases expression
increases expression

EXP
ISO

Methapyrilene results in decreased expression of FABP1 mRNA
Methapyrilene results in increased expression of FABP1 mRNA

PMID:15120968 PMID:28935588 PMID:30467583

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113

G

fatty acid binding protein 12

decreases expression

EXP

Methapyrilene results in decreased expression of FABP12 mRNA

NCBI chr 2:93,446,966...93,462,393
Ensembl chr 2:93,407,956...93,462,390

G

fatty acid binding protein 6

increases methylation

ISO

Methapyrilene results in increased methylation of FABP6 intron

NCBI chr10:28,565,054...28,569,727
Ensembl chr10:28,565,054...28,573,058

G

fatty acid binding protein 7

decreases expression

EXP

Methapyrilene results in decreased expression of FABP7 mRNA

NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907

G

fumarylacetoacetate hydrolase

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of FAH mRNA
Methapyrilene results in increased methylation of FAH intron

PMID:30157460 PMID:30467583

NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:147,957,935...147,981,046

G

fumarylacetoacetate hydrolase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of FAHD1 mRNA

NCBI chr10:14,378,058...14,379,497
Ensembl chr10:14,378,120...14,379,867

G

family with sequence similarity 107, member B

increases methylation
increases expression

ISO
EXP

Methapyrilene results in increased methylation of FAM107B intron
Methapyrilene results in increased expression of FAM107B mRNA

PMID:30157460 PMID:30467583

NCBI chr17:79,387,795...79,594,165
Ensembl chr17:79,387,795...79,594,288

G

family with sequence similarity 117, member A

increases methylation

ISO

Methapyrilene results in increased methylation of FAM117A intron

NCBI chr10:80,778,229...80,822,119
Ensembl chr10:80,755,883...80,822,119

G

family with sequence similarity 117, member B

decreases expression

EXP

Methapyrilene results in decreased expression of FAM117B mRNA

NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:68,834,354...68,902,543

G

family with sequence similarity 120 member B

decreases expression

EXP

Methapyrilene results in decreased expression of FAM120B mRNA

NCBI chr 1:64,993,104...65,058,160
Ensembl chr 1:65,012,060...65,058,160

G

family with sequence similarity 120 member C

affects methylation

ISO

Methapyrilene affects the methylation of FAM120C intron

NCBI chr X:23,765,089...23,922,059
Ensembl chr X:23,766,976...23,920,840

G

family with sequence similarity 13, member A

affects methylation

ISO

Methapyrilene affects the methylation of FAM13A intron

NCBI chr 4:89,386,685...89,485,940
Ensembl chr 4:89,388,569...89,485,988

G

FAM161 centrosomal protein B

increases methylation

ISO

Methapyrilene results in increased methylation of FAM161B intron

NCBI chr 6:109,722,073...109,750,003
Ensembl chr 6:109,722,569...109,750,036

G

family with sequence similarity 162, member A

increases expression

EXP

Methapyrilene results in increased expression of FAM162A mRNA

NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560

G

family with sequence similarity 168, member A

decreases expression

EXP

Methapyrilene results in decreased expression of FAM168A mRNA

NCBI chr 1:164,469,447...164,615,542
Ensembl chr 1:164,469,471...164,615,506

G

family with sequence similarity 169, member B

increases methylation

ISO

Methapyrilene results in increased methylation of FAM169BP intron

NCBI chr 1:131,288,780...131,378,548
Ensembl chr 1:131,288,799...131,370,145

G

family with sequence similarity 171, member A1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM171A1 intron

NCBI chr17:79,933,742...80,057,495
Ensembl chr17:79,934,050...80,057,495

G

family with sequence similarity 178, member B

increases methylation

ISO

Methapyrilene results in increased methylation of FAM178B intron

NCBI chr 9:46,301,734...46,409,571
Ensembl chr 9:46,301,734...46,410,686

G

FAM20A, golgi associated secretory pathway pseudokinase

increases methylation

ISO

Methapyrilene results in increased methylation of FAM20A intron

NCBI chr10:95,136,799...95,197,176
Ensembl chr10:95,142,458...95,197,053

G

FAM20C, golgi associated secretory pathway kinase

increases methylation

ISO

Methapyrilene results in increased methylation of FAM20C intron

NCBI chr12:20,940,654...20,999,072
Ensembl chr12:20,940,654...20,998,318

G

family with sequence similarity 210, member A

decreases expression

EXP

Methapyrilene results in decreased expression of FAM210A mRNA

NCBI chr18:64,116,274...64,155,971
Ensembl chr18:64,116,274...64,155,949

G

family with sequence similarity 222, member A

increases methylation

ISO

Methapyrilene results in increased methylation of FAM222A intron

NCBI chr12:47,647,221...47,693,703
Ensembl chr12:47,647,405...47,693,703

G

FAM3 metabolism regulating signaling molecule B

increases methylation

ISO

Methapyrilene results in increased methylation of FAM3B intron

NCBI chr11:50,300,926...50,333,296
Ensembl chr11:50,300,926...50,347,339

G

FAM3 metabolism regulating signaling molecule D

increases methylation

ISO

Methapyrilene results in increased methylation of FAM3D intron

NCBI chr15:18,969,737...19,003,276
Ensembl chr15:18,969,737...19,004,701

G

family with sequence similarity 47, member E

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM47E intron

NCBI chr14:15,769,441...15,805,911
Ensembl chr14:15,769,050...15,806,061

G

family with sequence similarity 53, member B

increases methylation

ISO

Methapyrilene results in increased methylation of FAM53B intron

NCBI chr 1:196,930,170...197,021,290
Ensembl chr 1:196,930,175...197,021,290

G

family with sequence similarity 78, member A

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM78A intron

NCBI chr 3:35,753,712...35,771,600
Ensembl chr 3:35,753,712...35,770,448

G

family with sequence similarity 83, member B

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM83B intron

NCBI chr 8:86,167,778...86,244,222
Ensembl chr 8:86,167,778...86,244,222

G

family with sequence similarity 83, member F

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM83F exon; Methapyrilene results in decreased methylation of FAM83F intron

NCBI chr 7:114,091,356...114,120,640
Ensembl chr 7:114,091,335...114,120,638

G

family with sequence similarity 83, member G

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM83G polyA tail

NCBI chr10:46,862,983...46,887,499
Ensembl chr10:46,862,369...46,886,277

G

family with sequence similarity 89, member B

increases expression

EXP

Methapyrilene results in increased expression of FAM89B mRNA

NCBI chr 1:212,445,101...212,447,164
Ensembl chr 1:212,445,102...212,446,738

G

family with sequence similarity 8, member A1

decreases expression

EXP

Methapyrilene results in decreased expression of FAM8A1 mRNA

NCBI chr17:18,232,834...18,241,736
Ensembl chr17:18,232,834...18,241,703

G

FA complementation group C

affects methylation

ISO

Methapyrilene affects the methylation of FANCC intron

NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FARP1 intron

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147

G

FERM, ARH/RhoGEF and pleckstrin domain protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of FARP2 mRNA

NCBI chr 9:101,501,061...101,609,092
Ensembl chr 9:101,501,102...101,609,086

G

fatty acid synthase

decreases expression

EXP

Methapyrilene results in decreased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

FAT atypical cadherin 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAT2 exon

NCBI chr10:39,864,765...39,957,027
Ensembl chr10:39,864,766...39,956,902

G

fibulin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBLN1 intron

NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965

G

fibulin 2

increases methylation

ISO

Methapyrilene results in increased methylation of FBLN2 intron; Methapyrilene results in increased methylation of FBLN2 promoter

NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029

G

fibulin 5

increases methylation

ISO

Methapyrilene results in increased methylation of FBLN5 intron

NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296

G

fibulin 7

affects methylation

ISO

Methapyrilene affects the methylation of FBLN7 intron

NCBI chr 3:136,564,825...136,601,205
Ensembl chr 3:136,564,917...136,601,198

G

fibrillin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBN1 intron

NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283

G

fructose-bisphosphatase 1

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of FBP1 mRNA
Methapyrilene results in increased methylation of FBP1 intron

PMID:16393664 PMID:30157460 PMID:30467583

NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746

G

fructose-bisphosphatase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBP2 intron

NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366

G

F-box and leucine-rich repeat protein 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBXL20 3' UTR

NCBI chr10:83,577,038...83,640,022
Ensembl chr10:83,577,038...83,639,977

G

F-box and leucine-rich repeat protein 7

affects methylation

ISO

Methapyrilene affects the methylation of FBXL7 intron

NCBI chr 2:78,870,236...79,239,697
Ensembl chr 2:78,871,287...79,239,697

G

F-box protein 17

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBXO17 exon

NCBI chr 1:93,129,776...93,151,983
Ensembl chr 1:93,129,849...93,151,981

G

F-box protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of FBXO3 mRNA

NCBI chr 3:110,872,185...110,904,479
Ensembl chr 3:110,872,220...110,904,479

G

F-box protein 31

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBXO31 intron

NCBI chr19:66,533,437...66,564,674
Ensembl chr19:66,533,437...66,564,674

G

F-box protein 6

increases methylation

ISO

Methapyrilene results in increased methylation of FBXO6 intron

NCBI chr 5:163,859,909...163,865,693
Ensembl chr 5:163,859,916...163,865,574

G

F-box protein 8

decreases expression

EXP

Methapyrilene results in decreased expression of FBXO8 mRNA

NCBI chr16:38,676,011...38,721,849
Ensembl chr16:38,676,014...38,721,906

G

f-box protein 9

decreases expression

EXP

Methapyrilene results in decreased expression of FBXO9 mRNA

NCBI chr 8:87,838,787...87,864,362
Ensembl chr 8:87,838,789...87,864,504

G

F-box and WD repeat domain containing 10

increases methylation

ISO

Methapyrilene results in increased methylation of FBXW10 intron

NCBI chr10:48,012,555...48,051,136
Ensembl chr10:47,958,677...48,051,136

G

F-box and WD repeat domain containing 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of FBXW8 intron

NCBI chr12:44,087,375...44,177,985
Ensembl chr12:44,087,375...44,177,985

G

Fc gamma receptor and transporter

increases methylation

ISO

Methapyrilene results in increased methylation of FCGRT intron

NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:104,710,909...104,720,532

G

FCH and mu domain containing endocytic adaptor 1

increases methylation

ISO

Methapyrilene results in increased methylation of FCHO1 intron

NCBI chr16:18,447,424...18,464,738
Ensembl chr16:18,447,424...18,464,698

G

FCH and mu domain containing endocytic adaptor 2

decreases expression

EXP

Methapyrilene results in decreased expression of FCHO2 mRNA

NCBI chr 2:31,813,356...31,916,471
Ensembl chr 2:31,814,950...31,915,445

G

FCH and double SH3 domains 2

decreases expression

EXP

Methapyrilene results in decreased expression of FCHSD2 mRNA

NCBI chr 1:164,775,916...165,097,391
Ensembl chr 1:164,775,926...165,097,391

G

ferredoxin 2

increases methylation

ISO

Methapyrilene results in increased methylation of FDX2 promoter

NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015

G

ferredoxin-fold anticodon binding domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of FDXACB1 mRNA

NCBI chr 8:60,009,818...60,014,625

G

FERM domain containing kindlin 1

increases methylation

ISO

Methapyrilene results in increased methylation of FERMT1 intron

NCBI chr 3:140,624,434...140,666,419
Ensembl chr 3:140,624,434...140,666,419

G

FERM domain containing kindlin 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of FERMT3 intron

NCBI chr 1:213,618,691...213,636,889
Ensembl chr 1:213,618,208...213,636,273

G

fetuin B

decreases expression

EXP

Methapyrilene results in decreased expression of FETUB mRNA

NCBI chr11:91,586,750...91,599,789
Ensembl chr11:91,586,748...91,599,310

G

free fatty acid receptor 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of FFAR4 intron

NCBI chr 1:245,286,009...245,304,029
Ensembl chr 1:245,285,883...245,304,031

G

fibrinogen alpha chain

decreases expression

EXP

Methapyrilene results in decreased expression of FGA mRNA

PMID:15120968 PMID:30467583

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

FYVE, RhoGEF and PH domain containing 4

increases methylation

ISO

Methapyrilene results in increased methylation of FGD4 promoter

NCBI chr11:97,904,182...98,055,190
Ensembl chr11:97,904,182...98,055,190

G

FYVE, RhoGEF and PH domain containing 5

increases methylation

ISO

Methapyrilene results in increased methylation of FGD5 exon; Methapyrilene results in increased methylation of FGD5 intron

NCBI chr 4:126,054,201...126,151,698
Ensembl chr 4:126,054,210...126,151,697

G

fibroblast growth factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of FGF1 intron

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393

G

fibroblast growth factor 12

affects methylation

ISO

Methapyrilene affects the methylation of FGF12 intron

NCBI chr11:85,501,947...86,069,543
Ensembl chr11:85,501,936...86,069,543

G

fibroblast growth factor 14

increases methylation

ISO

Methapyrilene results in increased methylation of FGF14 intron

NCBI chr15:107,442,800...108,086,486
Ensembl chr15:107,451,634...108,085,808

G

fibroblast growth factor 21

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of FGF21 mRNA
Methapyrilene results in decreased expression of FGF21 mRNA

PMID:22484513 PMID:30467583

NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056

G

FGGY carbohydrate kinase domain containing

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of FGGY mRNA
Methapyrilene results in increased methylation of FGGY intron

PMID:30157460 PMID:30467583

NCBI chr 5:115,514,573...115,901,713
Ensembl chr 5:115,472,211...115,901,714

G

fumarate hydratase

increases expression

EXP

Methapyrilene results in increased expression of FH protein

NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627

G

forkhead associated phosphopeptide binding domain 1

increases methylation

ISO

Methapyrilene results in increased methylation of FHAD1 intron

NCBI chr 5:159,474,111...159,593,455
Ensembl chr 5:159,474,158...159,593,367

G

fragile histidine triad diadenosine triphosphatase

affects methylation
increases expression

ISO

Methapyrilene affects the methylation of FHIT intron
Methapyrilene results in increased expression of FHIT mRNA

PMID:30157460 PMID:35690182

NCBI chr15:16,365,401...17,872,901
Ensembl chr15:16,747,338...17,872,621

G

four and a half LIM domains 1

increases expression

EXP

Methapyrilene results in increased expression of FHL1 mRNA

NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282

G

formin homology 2 domain containing 3

affects methylation

ISO

Methapyrilene affects the methylation of FHOD3 intron

NCBI chr18:16,267,830...16,700,508
Ensembl chr18:16,267,977...16,700,508

G

FGF1 intracellular binding protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of FIBP exon

NCBI chr 1:212,197,216...212,201,732
Ensembl chr 1:212,197,416...212,201,731

G

filamin A interacting protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FILIP1 intron

NCBI chr 8:89,641,509...89,836,772
Ensembl chr 8:89,644,579...89,802,771

G

filamin A interacting protein 1-like

increases methylation

ISO

Methapyrilene results in increased methylation of FILIP1L intron

NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402

G

FKBP prolyl isomerase 4

increases expression

EXP

Methapyrilene results in increased expression of FKBP4 mRNA

NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918

G

FKBP prolyl isomerase 5

decreases expression

EXP

Methapyrilene results in decreased expression of FKBP5 mRNA

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118

G

flavin adenine dinucleotide synthetase 1

decreases expression

EXP

Methapyrilene results in decreased expression of FLAD1 mRNA

NCBI chr 2:177,117,183...177,126,650
Ensembl chr 2:177,117,655...177,126,650

G

folliculin

decreases methylation

ISO

Methapyrilene results in decreased methylation of FLCN intron

NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309

G

Fli-1 proto-oncogene, ETS transcription factor

increases methylation

ISO

Methapyrilene results in increased methylation of FLI1 intron

NCBI chr 8:39,089,526...39,209,511
Ensembl chr 8:39,089,533...39,208,557

G

filamin A

increases methylation

ISO

Methapyrilene results in increased methylation of FLNA exon

NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343

G

filamin B

decreases expression

EXP

Methapyrilene results in decreased expression of FLNB mRNA

NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209

G

Fms related receptor tyrosine kinase 1

increases methylation

ISO

Methapyrilene results in increased methylation of FLT1 intron

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

Fms related receptor tyrosine kinase 3

increases methylation

ISO

Methapyrilene results in increased methylation of FLT3 intron

NCBI chr12:12,660,035...12,735,584
Ensembl chr12:12,659,946...12,735,581

G

FLVCR choline and putative heme transporter 2

increases methylation

ISO

Methapyrilene results in increased methylation of FLVCR2 intron

NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:111,139,295...111,203,345

G

formin 1

increases methylation

ISO

Methapyrilene results in increased methylation of FMN1 intron

NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:120,555,431...120,933,124

G

formin 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of FMN2 intron

NCBI chr13:88,986,863...89,303,789
Ensembl chr13:88,986,842...89,303,789

G

formin-like 2

increases methylation

ISO

Methapyrilene results in increased methylation of FMNL2 intron

NCBI chr 3:57,758,236...58,033,832
Ensembl chr 3:57,758,191...58,033,831

G

formin-like 3

increases methylation

ISO

Methapyrilene results in increased methylation of FMNL3 intron

NCBI chr 7:132,333,130...132,384,483
Ensembl chr 7:132,333,130...132,384,483

G

flavin containing dimethylaniline monoxygenase 5

decreases expression

EXP

Methapyrilene results in decreased expression of FMO5 mRNA

NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464

G

fibronectin 1

decreases expression

EXP

Methapyrilene results in decreased expression of FN1 mRNA

PMID:15890375 PMID:30467583

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

fibronectin type III domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of FNDC1 intron

NCBI chr 1:49,686,856...49,769,263
Ensembl chr 1:49,686,856...49,769,263

G

fibronectin type III domain containing 3a

decreases expression

EXP

Methapyrilene results in decreased expression of FNDC3A mRNA

NCBI chr15:54,099,510...54,276,963
Ensembl chr15:54,099,510...54,276,407

G

fibronectin type III domain containing 3B

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of FNDC3B intron
Methapyrilene results in decreased expression of FNDC3B mRNA

PMID:30157460 PMID:30467583

NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306

G

fibronectin type III domain containing 5

increases methylation

ISO

Methapyrilene results in increased methylation of FNDC5 intron

NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:146,751,416...146,778,540

G

farnesyltransferase, CAAX box, subunit beta

decreases methylation

ISO

Methapyrilene results in decreased methylation of FNTB intron

NCBI chr 6:101,269,657...101,352,716
Ensembl chr 6:101,269,671...101,352,716

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

Methapyrilene results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FOS like 1, AP-1 transcription factor subunit

increases expression

EXP

Methapyrilene results in increased expression of FOSL1 mRNA

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391

G

forkhead box N3

increases methylation

ISO

Methapyrilene results in increased methylation of FOXN3 intron

NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040

G

forkhead box N4

decreases methylation

ISO

Methapyrilene results in decreased methylation of FOXN4 intron

NCBI chr12:47,997,308...48,020,526
Ensembl chr12:48,000,257...48,020,526

G

forkhead box O3

increases methylation

ISO

Methapyrilene results in increased methylation of FOXO3 intron

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

forkhead box O6

decreases methylation

ISO

Methapyrilene results in decreased methylation of FOXO6 intron

NCBI chr 5:139,141,329...139,161,629
Ensembl chr 5:139,141,185...139,161,629

G

forkhead box P1

decreases expression

EXP

Methapyrilene results in decreased expression of FOXP1 mRNA

NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:133,122,055...133,500,272

G

forkhead box P2

increases methylation

ISO

Methapyrilene results in increased methylation of FOXP2 intron

NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:44,099,959...44,677,696

G

FAD-dependent oxidoreductase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of FOXRED1 mRNA

NCBI chr 8:41,789,557...41,818,064
Ensembl chr 8:41,808,843...41,817,980

G

folylpolyglutamate synthase

decreases expression

EXP

Methapyrilene results in decreased expression of FPGS mRNA

NCBI chr 3:36,370,505...36,391,314
Ensembl chr 3:36,370,300...36,391,068

G

FRA10A associated CGG repeat 1

decreases expression

EXP

Methapyrilene results in decreased expression of FRA10AC1 mRNA

NCBI chr 1:245,381,538...245,413,879
Ensembl chr 1:245,366,451...245,414,189

G

Fras1 related extracellular matrix 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FREM1 intron

NCBI chr 5:102,367,201...102,515,464
Ensembl chr 5:102,367,201...102,515,404

G

FRAS1 related extracellular matrix 2

decreases expression

ISO

Methapyrilene results in decreased expression of FREM2 mRNA

NCBI chr 2:139,753,055...139,891,046
Ensembl chr 2:139,753,055...139,891,046

G

FERM domain containing 4A

affects methylation

ISO

Methapyrilene affects the methylation of FRMD4A intron

NCBI chr17:78,577,062...79,167,924
Ensembl chr17:78,579,277...79,167,663

G

FERM domain containing 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of FRMD8 intron

NCBI chr 1:212,572,534...212,593,181
Ensembl chr 1:212,572,537...212,592,695

G

FERM and PDZ domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FRMPD1 intron

NCBI chr 5:64,238,730...64,340,778
Ensembl chr 5:64,238,768...64,340,776

G

FERM and PDZ domain containing 3

increases methylation

ISO

Methapyrilene results in increased methylation of FRMPD3 intron

NCBI chr X:108,752,511...108,902,393
Ensembl chr X:108,752,716...108,901,496

G

fibronectin type III and SPRY domain containing 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of FSD2 intron

NCBI chr 1:144,898,499...144,931,753
Ensembl chr 1:144,898,502...144,931,704

G

follistatin

increases expression

EXP

Methapyrilene results in increased expression of FST mRNA

NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491

G

follistatin-like 4

increases methylation

ISO

Methapyrilene results in increased methylation of FSTL4 exon; Methapyrilene results in increased methylation of FSTL4 intron

NCBI chr10:37,412,288...37,845,405
Ensembl chr10:37,412,288...37,845,393

G

follistatin-like 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of FSTL5 intron

NCBI chr 2:163,156,576...163,825,140
Ensembl chr 2:163,156,576...163,825,140

G

formimidoyltransferase cyclodeaminase

decreases expression

EXP

Methapyrilene results in decreased expression of FTCD mRNA

NCBI chr20:12,054,710...12,068,219
Ensembl chr20:12,054,711...12,068,237

G

ferritin light chain 1

decreases expression
increases expression

ISO
EXP

Methapyrilene results in decreased expression of FTL mRNA
Methapyrilene results in increased expression of FTL mRNA
Methapyrilene results in increased expression of FTL protein

NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915

G

FTO, alpha-ketoglutarate dependent dioxygenase

decreases methylation

ISO

Methapyrilene results in decreased methylation of FTO intron

NCBI chr19:31,456,749...31,865,011
Ensembl chr19:31,522,293...31,864,957

G

FTX transcript, XIST regulator

increases methylation

ISO

Methapyrilene results in increased methylation of FTX intron

NCBI chr X:72,654,112...72,696,097

G

far upstream element binding protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of FUBP3 mRNA

NCBI chr 3:35,253,216...35,302,282
Ensembl chr 3:35,253,306...35,302,280

G

FUN14 domain containing 2

decreases expression

EXP

Methapyrilene results in decreased expression of FUNDC2 mRNA

NCBI chr18:142,829...155,123
Ensembl chr18:142,640...155,674

G

forty-two-three domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of FYTTD1 mRNA

NCBI chr11:81,383,040...81,412,604
Ensembl chr11:81,383,040...81,412,599

G

G2 protein

increases methylation

ISO

Methapyrilene results in increased methylation of KIAA1549L intron

NCBI chr 3:110,961,478...111,237,308
Ensembl chr 3:110,961,478...111,237,223

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

EXP

Methapyrilene results in decreased expression of G6PC1 mRNA

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033

G

glucose-6-phosphate dehydrogenase

multiple interactions
increases expression

EXP

[Diethylnitrosamine co-treated with Methapyrilene] results in increased expression of G6PD protein
Methapyrilene results in increased expression of G6PD mRNA

PMID:28903497 PMID:30467583

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

GABA type A receptor associated protein like 2

increases expression

EXP

Methapyrilene results in increased expression of GABARAPL2 mRNA

NCBI chr19:56,819,826...56,830,662
Ensembl chr19:56,819,791...56,830,660

G

gamma-aminobutyric acid type B receptor subunit 2

increases methylation

ISO

Methapyrilene results in increased methylation of GABBR2 intron

NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:65,743,073...66,083,695

G

GA binding protein transcription factor subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of GABPA mRNA

NCBI chr11:37,375,040...37,404,060
Ensembl chr11:37,375,084...37,404,059

G

GA binding protein transcription factor subunit beta 2

increases methylation

ISO

Methapyrilene results in increased methylation of GABPB2 polyA tail

NCBI chr 2:185,444,309...185,484,200
Ensembl chr 2:185,450,296...185,483,589

G

gamma-aminobutyric acid type A receptor subunit alpha 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GABRA1 polyA tail

NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442

G

gamma-aminobutyric acid type A receptor subunit alpha 3

increases methylation

ISO

Methapyrilene results in increased methylation of GABRA3 exon; Methapyrilene results in increased methylation of GABRA3 intron

NCBI chr X:155,301,979...155,543,870
Ensembl chr X:155,303,928...155,543,863

G

gamma-aminobutyric acid type A receptor subunit delta

increases methylation

ISO

Methapyrilene results in increased methylation of GABRD intron

NCBI chr 5:171,240,813...171,252,709
Ensembl chr 5:171,240,789...171,253,094

G

gamma-aminobutyric acid type A receptor subunit rho 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GABRR1 intron

NCBI chr 5:52,320,475...52,357,549
Ensembl chr 5:52,320,475...52,357,549

G

growth arrest and DNA-damage-inducible, alpha

increases expression

EXP

Methapyrilene results in increased expression of GADD45A mRNA

PMID:15890375 PMID:22484513 PMID:25242409 PMID:28935588

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth arrest and DNA-damage-inducible, beta

increases expression

EXP

Methapyrilene results in increased expression of GADD45B mRNA

NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718

G

cyclin G associated kinase

increases methylation

ISO

Methapyrilene results in increased methylation of GAK intron

NCBI chr14:1,234,272...1,308,492
Ensembl chr14:1,234,266...1,323,974

G

galactose-3-O-sulfotransferase 2

increases methylation

ISO

Methapyrilene results in increased methylation of GAL3ST2 polyA tail

NCBI chr 9:101,823,815...101,836,507
Ensembl chr 9:101,823,815...101,836,507

G

galactose mutarotase

decreases expression

EXP

Methapyrilene results in decreased expression of GALM mRNA

NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417

G

galactosamine (N-acetyl)-6-sulfatase

increases methylation

ISO

Methapyrilene results in increased methylation of GALNS intron

NCBI chr19:67,537,175...67,570,900
Ensembl chr19:67,534,737...67,571,191

G

polypeptide N-acetylgalactosaminyltransferase 11

decreases expression

EXP

Methapyrilene results in decreased expression of GALNT11 mRNA

NCBI chr 4:10,571,464...10,604,974
Ensembl chr 4:10,571,464...10,604,974

G

polypeptide N-acetylgalactosaminyltransferase 17

increases methylation

ISO

Methapyrilene results in increased methylation of WBSCR17 intron

NCBI chr12:30,959,460...31,418,150
Ensembl chr12:30,959,447...31,418,149

G

polypeptide N-acetylgalactosaminyltransferase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of GALNT2 intron

NCBI chr19:69,110,657...69,222,237
Ensembl chr19:69,110,657...69,222,237

G

polypeptide N-acetylgalactosaminyltransferase 8

increases methylation

ISO

Methapyrilene results in increased methylation of GALNT8 promoter

NCBI chr 4:161,307,603...161,336,485

G

polypeptide N-acetylgalactosaminyltransferase-like 6

increases methylation

ISO

Methapyrilene results in increased methylation of GALNTL6 intron

NCBI chr16:36,203,674...37,454,709
Ensembl chr16:36,204,614...37,452,780

G

glucosidase II alpha subunit

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of GANAB intron; Methapyrilene results in increased methylation of GANAB promoter
Methapyrilene results in decreased expression of GANAB mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:215,222,918...215,242,808
Ensembl chr 1:215,222,995...215,243,036

G

growth associated protein 43

increases methylation

ISO

Methapyrilene results in increased methylation of GAP43 exon

NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797

G

GTPase activating protein and VPS9 domains 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GAPVD1 intron

NCBI chr 3:38,365,854...38,439,403
Ensembl chr 3:38,365,854...38,439,390

G

GRB2 associated regulator of MAPK1 subtype 1

increases methylation

ISO

Methapyrilene results in increased methylation of GAREM intron

NCBI chr18:12,695,082...12,860,219
Ensembl chr18:12,695,082...12,860,219

G

growth arrest-specific 2

decreases expression

EXP

Methapyrilene results in decreased expression of GAS2 mRNA

NCBI chr 1:110,587,952...110,721,572
Ensembl chr 1:110,717,312...110,718,541

G

growth arrest specific 6

increases expression

EXP

Methapyrilene results in increased expression of GAS6 mRNA

NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088

G

growth arrest specific 7

increases methylation

ISO

Methapyrilene results in increased methylation of GAS7 exon; Methapyrilene results in increased methylation of GAS7 intron

NCBI chr10:52,651,690...52,882,244
Ensembl chr10:52,651,690...52,882,244

G

GATA binding protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of GATA2 exon; Methapyrilene results in increased methylation of GATA2 polyA tail

NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055

G

GATA zinc finger domain containing 2A

increases methylation

ISO

Methapyrilene results in increased methylation of GATAD2A intron

NCBI chr16:19,463,500...19,553,497
Ensembl chr16:19,463,500...19,553,497

G

glutamine amidotransferase class 1 domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GATD1 exon

NCBI chr 1:205,936,189...205,942,121
Ensembl chr 1:205,936,687...205,942,779

G

glucosylceramidase beta 3

increases methylation

ISO

Methapyrilene results in increased methylation of GBA3 intron

NCBI chr14:64,787,601...64,934,043
Ensembl chr14:64,787,601...64,934,043

G

1,4-alpha-glucan branching enzyme 1

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of GBE1 intron
Methapyrilene results in decreased expression of GBE1 mRNA

PMID:30157460 PMID:30467583

NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638

G

globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)

increases methylation

ISO

Methapyrilene results in increased methylation of GBGT1 5' UTR

NCBI chr 3:32,219,370...32,227,737

G

grancalcin

decreases expression

EXP

Methapyrilene results in decreased expression of GCA mRNA

NCBI chr 3:67,705,874...67,738,475
Ensembl chr 3:67,705,890...67,737,387

G

glucagon receptor

increases methylation

ISO

Methapyrilene results in increased methylation of GCGR intron

NCBI chr10:106,306,803...106,314,970
Ensembl chr10:106,306,559...106,314,969

G

glucokinase regulator

decreases expression

EXP

Methapyrilene results in decreased expression of GCKR mRNA

NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627

G

glutamate-cysteine ligase, catalytic subunit

increases expression

EXP

Methapyrilene results in increased expression of GCLC mRNA; Methapyrilene results in increased expression of GCLC protein

PMID:15890375 PMID:19523481 PMID:28935588 PMID:30467583

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glial cells missing transcription factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GCM1 intron

NCBI chr 8:87,805,993...87,819,229
Ensembl chr 8:87,805,993...87,819,229

G

glucosaminyl (N-acetyl) transferase family member 7

increases methylation

ISO

Methapyrilene results in increased methylation of GCNT7 intron

NCBI chr 3:181,637,406...181,647,839
Ensembl chr 3:181,637,406...181,641,460

G

guanine deaminase

increases methylation

ISO

Methapyrilene results in increased methylation of GDA intron

NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348

G

growth differentiation factor 15

increases expression

EXP

Methapyrilene results in increased expression of GDF15 mRNA

PMID:15890375 PMID:30467583

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022

G

growth differentiation factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of GDF3 intron

NCBI chr 4:157,503,547...157,507,923
Ensembl chr 4:157,502,884...157,507,907

G

glycerophosphodiester phosphodiesterase domain containing 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of GDPD5 intron

NCBI chr 1:163,091,844...163,173,559
Ensembl chr 1:163,091,833...163,173,559

G

glial fibrillary acidic protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of GFAP exon

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

G elongation factor, mitochondrial 1

decreases expression

EXP

Methapyrilene results in decreased expression of GFM1 mRNA

NCBI chr 2:154,010,601...154,055,523
Ensembl chr 2:154,010,614...154,065,805

G

GDNF family receptor alpha 1

decreases expression

EXP

Methapyrilene results in decreased expression of GFRA1 mRNA

NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501

G

GDNF family receptor alpha 2

increases methylation

ISO

Methapyrilene results in increased methylation of GFRA2 3' UTR; Methapyrilene results in increased methylation of GFRA2 intron

NCBI chr15:52,351,499...52,443,369
Ensembl chr15:52,351,514...52,477,782

G

gamma-glutamyl carboxylase

decreases expression

EXP

Methapyrilene results in decreased expression of GGCX mRNA

NCBI chr 4:106,027,918...106,043,653
Ensembl chr 4:106,027,912...106,043,923

G

gamma-glutamyltransferase 5

increases methylation

ISO

Methapyrilene results in increased methylation of GGT5 intron

NCBI chr20:13,042,694...13,070,960
Ensembl chr20:13,042,696...13,070,892

G

growth hormone inducible transmembrane protein

decreases expression

EXP

Methapyrilene results in decreased expression of GHITM mRNA

NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,905,806...12,918,123

G

growth hormone receptor

increases expression

EXP

Methapyrilene results in increased expression of GHR mRNA

NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331

G

gypsy retrotransposon integrase 1

decreases expression

EXP

Methapyrilene results in decreased expression of GIN1 mRNA

NCBI chr 9:105,740,914...105,762,357
Ensembl chr 9:105,742,094...105,762,357

G

gap junction protein, beta 1

increases methylation

ISO

Methapyrilene results in increased methylation of GJB1 intron

NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843

G

gap junction protein, beta 2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of GJB2 mRNA
Methapyrilene results in increased methylation of GJB2 promoter

PMID:30157460 PMID:30467583

NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877

G

gap junction protein, beta 4

increases methylation

ISO

Methapyrilene results in increased methylation of GJB4 exon

NCBI chr 5:144,948,231...144,964,014
Ensembl chr 5:144,951,184...144,964,097

G

gap junction protein, delta 3

decreases methylation
increases expression

ISO

Methapyrilene results in decreased methylation of GJD3 promoter
Methapyrilene results in increased expression of GJD3 mRNA

NCBI chr10:84,429,923...84,432,011
Ensembl chr10:84,429,036...84,433,870

G

glycerol kinase

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of GK promoter
Methapyrilene results in decreased expression of GK mRNA

PMID:30157460 PMID:30467583

NCBI chr X:54,106,708...54,189,940
Ensembl chr X:54,112,214...54,196,701

G

glycine decarboxylase

decreases expression

EXP

Methapyrilene results in decreased expression of GLDC mRNA

NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604

G

GLI family zinc finger 2

affects methylation
decreases methylation

ISO

Methapyrilene affects the methylation of GLI2 intron
Methapyrilene results in decreased methylation of GLI2 polyA tail

NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418

G

GLIS family zinc finger 1

increases methylation

ISO

Methapyrilene results in increased methylation of GLIS1 intron

NCBI chr 5:127,450,934...127,640,929
Ensembl chr 5:127,451,293...127,640,928

G

GLIS family zinc finger 2

increases methylation

ISO

Methapyrilene results in increased methylation of GLIS2 intron

NCBI chr10:11,457,594...11,484,948
Ensembl chr10:11,457,792...11,477,995

G

glyoxalase domain containing 4

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of GLOD4 mRNA
Methapyrilene results in increased methylation of GLOD4 intron

PMID:30157460 PMID:30467583

NCBI chr10:61,575,770...61,594,111

G

glutaminase 2

decreases expression

EXP

Methapyrilene results in decreased expression of GLS2 mRNA

NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013

G

glycosyltransferase 1 domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of GLT1D1 intron

NCBI chr12:34,611,942...34,685,591
Ensembl chr12:34,612,643...34,685,468

G

glycosyltransferase 8 domain containing 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of GLT8D2 intron

NCBI chr 7:22,917,055...22,968,616
Ensembl chr 7:22,917,100...22,968,930

G

glutamate dehydrogenase 1

decreases expression

EXP

Methapyrilene results in decreased expression of GLUD1 mRNA

NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210

G

glycine-N-acyltransferase-like 2

decreases expression

EXP

Methapyrilene results in decreased expression of GLYATL2 mRNA

NCBI chr 1:219,232,154...219,265,142
Ensembl chr 1:219,232,103...219,266,322

G

glycerate kinase

decreases expression

EXP

Methapyrilene results in decreased expression of GLYCTK mRNA

NCBI chr 8:115,676,071...115,681,403
Ensembl chr 8:115,676,072...115,681,091

G

glyoxylate reductase 1 homolog

decreases expression

EXP

Methapyrilene results in decreased expression of GLYR1 mRNA

NCBI chr10:11,038,577...11,074,093
Ensembl chr10:11,038,568...11,074,090

G

GDP-mannose 4, 6-dehydratase

affects methylation

ISO

Methapyrilene affects the methylation of GMDS intron

NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,304,056...32,830,706

G

glucocorticoid modulatory element binding protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GMEB1 intron

NCBI chr 5:149,703,035...149,746,474
Ensembl chr 5:149,705,825...149,737,259

G

glia maturation factor, beta

decreases expression

EXP

Methapyrilene results in decreased expression of GMFB mRNA

NCBI chr15:22,549,705...22,560,125
Ensembl chr15:22,547,034...22,560,308

G

geminin, DNA replication inhibitor

increases expression

EXP

Methapyrilene results in increased expression of GMNN mRNA

NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,729,824...40,738,068

G

G protein subunit alpha 15

increases methylation

ISO

Methapyrilene results in increased methylation of GNA15 polyA tail

NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,835,357...8,856,268

G

G protein subunit alpha i1

decreases expression

EXP

Methapyrilene results in decreased expression of GNAI1 mRNA

NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198

G

G protein subunit alpha o1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GNAO1 3' UTR; Methapyrilene results in decreased methylation of GNAO1 intron

NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437

G

G protein subunit beta 5

decreases expression

EXP

Methapyrilene results in decreased expression of GNB5 mRNA

NCBI chr 8:84,956,629...84,985,576
Ensembl chr 8:84,953,815...84,986,888

G

G protein subunit gamma 12

increases methylation

ISO

Methapyrilene results in increased methylation of GNG12 intron

NCBI chr 4:97,340,830...97,464,422
Ensembl chr 4:97,340,472...97,464,476

G

G protein subunit gamma 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of GNG2 intron

NCBI chr15:4,365,222...4,466,060
Ensembl chr15:4,365,135...4,466,059

G

G protein subunit gamma 4

increases methylation

ISO

Methapyrilene results in increased methylation of GNG4 intron

NCBI chr17:93,432,791...93,481,709
Ensembl chr17:93,433,195...93,481,709

G

G protein subunit gamma 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of GNG7 intron

NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:9,348,218...9,411,923

G

G protein nucleolar 3 like

decreases expression

EXP

Methapyrilene results in decreased expression of GNL3L mRNA

NCBI chr X:23,404,324...23,437,501
Ensembl chr X:23,404,324...23,439,315

G

glycine N-methyltransferase

increases expression

EXP
ISO

Methapyrilene results in increased expression of GNMT protein
Methapyrilene results in increased expression of GNMT mRNA

PMID:30467583 PMID:35690182

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692

G

glyceronephosphate O-acyltransferase

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of GNPAT mRNA
Methapyrilene results in decreased methylation of GNPAT intron

PMID:30157460 PMID:30467583

NCBI chr19:69,719,707...69,746,244
Ensembl chr19:69,719,394...69,746,244

G

golgin A3

decreases methylation

ISO

Methapyrilene results in decreased methylation of GOLGA3 intron

NCBI chr12:52,112,129...52,160,311
Ensembl chr12:52,114,590...52,160,226

G

golgin A4

decreases expression

EXP

Methapyrilene results in decreased expression of GOLGA4 mRNA

NCBI chr 8:127,085,830...127,163,227
Ensembl chr 8:127,085,848...127,163,603

G

golgin A5

decreases expression

EXP

Methapyrilene results in decreased expression of GOLGA5 mRNA

NCBI chr 6:127,377,244...127,405,404
Ensembl chr 6:127,377,236...127,405,403

G

golgi integral membrane protein 4

decreases expression

EXP

Methapyrilene results in decreased expression of GOLIM4 mRNA

NCBI chr 2:162,939,429...163,031,901
Ensembl chr 2:162,939,429...163,031,901

G

gon-4 like

decreases methylation

ISO

Methapyrilene results in decreased methylation of GON4L intron

NCBI chr 2:176,531,274...176,604,446
Ensembl chr 2:176,531,274...176,604,444

G

golgi SNAP receptor complex member 1

affects expression

EXP

Methapyrilene affects the expression of GOSR1 mRNA

NCBI chr10:62,068,662...62,105,442
Ensembl chr10:61,948,693...62,105,324

G

glutamic-oxaloacetic transaminase 1

decreases expression

EXP

Methapyrilene results in decreased expression of GOT1 mRNA

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glycoprotein A33

increases methylation

ISO

Methapyrilene results in increased methylation of GPA33 exon

NCBI chr13:80,914,119...80,947,738
Ensembl chr13:80,912,430...80,948,903

G

glycerol-3-phosphate acyltransferase, mitochondrial

decreases expression

EXP

Methapyrilene results in decreased expression of GPAM mRNA

NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911

G

G patch domain and ankyrin repeats 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GPANK1 exon

NCBI chr20:3,702,309...3,705,476
Ensembl chr20:3,702,309...3,705,306

G

glycerol-3-phosphate acyltransferase 4

increases methylation

ISO

Methapyrilene results in increased methylation of GPAT4 intron

NCBI chr16:75,515,935...75,555,431
Ensembl chr16:75,521,640...75,557,847

G

G patch domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of GPATCH2 intron

NCBI chr13:101,316,413...101,457,109
Ensembl chr13:101,316,413...101,457,109

G

glypican 3

increases methylation

ISO

Methapyrilene results in increased methylation of GPC3 intron

NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639

G

glypican 4

decreases expression

EXP

Methapyrilene results in decreased expression of GPC4 mRNA

NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057

G

glypican 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of GPC5 intron

NCBI chr15:98,614,499...100,051,285
Ensembl chr15:98,646,340...100,051,514

G

glycerophosphocholine phosphodiesterase 1

decreases expression

EXP

Methapyrilene results in decreased expression of GPCPD1 mRNA

NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:140,240,575...140,285,372

G

glycerol-3-phosphate dehydrogenase 1

increases methylation

ISO

Methapyrilene results in increased methylation of GPD1 intron

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368

G

gephyrin

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of GPHN mRNA
Methapyrilene results in increased methylation of GPHN intron

PMID:30157460 PMID:30467583

NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:102,687,423...103,216,674

G

glycosylphosphatidylinositol specific phospholipase D1

increases methylation

ISO

Methapyrilene results in increased methylation of GPLD1 intron

NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975

G

glycoprotein m6b

increases methylation

ISO

Methapyrilene results in increased methylation of GPM6B intron

NCBI chr X:31,689,485...31,836,199
Ensembl chr X:31,690,359...31,733,272

G

G protein-coupled receptor 107

decreases expression

EXP

Methapyrilene results in decreased expression of GPR107 mRNA

NCBI chr 3:34,832,462...34,893,692
Ensembl chr 3:34,832,480...34,893,654

G

G protein-coupled receptor 108

decreases methylation

ISO

Methapyrilene results in decreased methylation of GPR108 intron

NCBI chr 9:2,207,716...2,218,738
Ensembl chr 9:2,207,726...2,219,750

G

G protein-coupled receptor 137B

increases methylation

ISO

Methapyrilene results in increased methylation of GPR137B intron

NCBI chr17:92,987,792...93,026,003
Ensembl chr17:92,942,559...93,025,911

G

G protein-coupled receptor 146

decreases expression

EXP

Methapyrilene results in decreased expression of GPR146 mRNA

NCBI chr12:20,365,790...20,381,122
Ensembl chr12:20,364,269...20,381,345

G

G protein-coupled receptor 156

increases methylation

ISO

Methapyrilene results in increased methylation of GPR156 polyA tail

NCBI chr11:76,228,104...76,320,890
Ensembl chr11:76,228,104...76,320,890

G

G protein-coupled receptor 157

increases methylation

ISO

Methapyrilene results in increased methylation of GPR157 intron

NCBI chr 5:165,833,651...165,849,376
Ensembl chr 5:165,833,673...165,851,280

G

G protein-coupled receptor 32

increases methylation

ISO

Methapyrilene results in increased methylation of GPR32 exon

NCBI chr 1:103,893,405...103,894,667

G

G protein regulated inducer of neurite outgrowth 2

increases methylation

ISO

Methapyrilene results in increased methylation of GPRIN2 intron

NCBI chr16:9,502,697...9,518,901
Ensembl chr16:9,502,711...9,513,259

G

G-protein signaling modulator 1

increases methylation

ISO

Methapyrilene results in increased methylation of GPSM1 intron

NCBI chr 3:29,538,929...29,565,921
Ensembl chr 3:29,526,802...29,565,920

G

glutamic--pyruvic transaminase

increases expression
increases activity
decreases expression

EXP

Methapyrilene results in increased expression of GPT protein
Methapyrilene results in increased activity of GPT protein
Methapyrilene results in decreased expression of GPT mRNA

PMID:24863736 PMID:28529062 PMID:30467583

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutamic--pyruvic transaminase 2

affects methylation

ISO

Methapyrilene affects the methylation of GPT2 intron

NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917

G

glutathione peroxidase 2

increases expression

EXP

Methapyrilene results in increased expression of GPX2 mRNA

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862

G

glutathione peroxidase 3

increases expression

EXP

Methapyrilene results in increased expression of GPX3 mRNA

NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405

G

GRAM domain containing 1B

increases methylation

ISO

Methapyrilene results in increased methylation of GRAMD1B intron

NCBI chr 8:49,551,642...49,790,965
Ensembl chr 8:49,556,332...49,791,052

G

GRB2-related adaptor protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of GRAP2 intron

NCBI chr 7:113,997,356...114,071,073
Ensembl chr 7:113,997,307...114,075,367

G

growth factor receptor bound protein 14

decreases expression

EXP

Methapyrilene results in decreased expression of GRB14 mRNA

NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:69,976,339...70,091,921

G

growth factor receptor bound protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of GRB2 intron

NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138

G

gene rich cluster, C10 gene

increases methylation

ISO

Methapyrilene results in increased methylation of C12ORF57 promoter

NCBI chr 4:159,237,562...159,239,223

G

growth regulating estrogen receptor binding 1

increases methylation

ISO

Methapyrilene results in increased methylation of GREB1 intron

NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126

G

glyoxylate and hydroxypyruvate reductase

decreases expression

ISO

Methapyrilene results in decreased expression of GRHPR mRNA

NCBI chr 5:64,029,856...64,039,287
Ensembl chr 5:64,022,368...64,039,276

G

glutamate ionotropic receptor delta type subunit 1

affects methylation

ISO

Methapyrilene affects the methylation of GRID1 intron

NCBI chr16:10,145,018...10,894,184
Ensembl chr16:10,144,964...10,891,946

G

Grid2 interacting protein

increases methylation

ISO

Methapyrilene results in increased methylation of GRID2IP intron

NCBI chr12:16,274,809...16,317,319
Ensembl chr12:16,280,168...16,317,278

G

glutamate ionotropic receptor kainate type subunit 1

increases methylation

ISO

Methapyrilene results in increased methylation of GRIK1 intron

NCBI chr11:40,655,974...41,056,966
Ensembl chr11:40,655,975...41,056,517

G

glutamate ionotropic receptor kainate type subunit 4

affects methylation

ISO

Methapyrilene affects the methylation of GRIK4 intron

NCBI chr 8:51,802,045...52,228,751
Ensembl chr 8:51,802,058...52,102,063

G

glutamate ionotropic receptor kainate type subunit 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of GRIK5 intron

NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:89,733,741...89,794,962

G

glutamate ionotropic receptor NMDA type subunit 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GRIN1 intron

NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754

G

glutamate ionotropic receptor NMDA type subunit 2A

increases methylation

ISO

Methapyrilene results in increased methylation of GRIN2A intron

NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378

G

glutamate ionotropic receptor NMDA type subunit 2B

increases methylation

ISO

Methapyrilene results in increased methylation of GRIN2B intron

NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570

G

glutamate receptor interacting protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of GRIP2 intron

NCBI chr 4:125,828,609...125,913,693
Ensembl chr 4:125,828,609...125,913,750

G

G protein-coupled receptor kinase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of GRK1 intron

NCBI chr16:82,821,184...82,837,971
Ensembl chr16:82,826,022...82,837,971

G

G protein-coupled receptor kinase 5

increases methylation

ISO

Methapyrilene results in increased methylation of GRK5 intron

NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928

G

G protein-coupled receptor kinase 6

decreases expression

EXP

Methapyrilene results in decreased expression of GRK6 mRNA

NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,182,160...9,197,954

G

glutamate metabotropic receptor 4

increases methylation

ISO

Methapyrilene results in increased methylation of GRM4 intron

NCBI chr20:5,486,024...5,574,668
Ensembl chr20:5,482,977...5,574,668

G

glutamate metabotropic receptor 5

increases methylation

ISO

Methapyrilene results in increased methylation of GRM5 intron

NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:150,733,678...151,296,649

G

GrpE-like 1, mitochondrial

increases expression

EXP

Methapyrilene results in increased expression of GRPEL1 mRNA

NCBI chr14:78,517,049...78,522,868
Ensembl chr14:78,517,052...78,522,861

G

goosecoid homeobox

increases methylation

ISO

Methapyrilene results in increased methylation of GSC polyA tail

NCBI chr 6:129,152,836...129,154,875
Ensembl chr 6:129,152,836...129,154,875

G

gasdermin A

increases methylation

ISO

Methapyrilene results in increased methylation of GSDMA intron

NCBI chr10:84,110,590...84,135,804
Ensembl chr10:84,123,314...84,135,804

G

gasdermin D

decreases methylation

ISO

Methapyrilene results in decreased methylation of GSDMD intron

NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722

G

GSG1-like

increases methylation

ISO

Methapyrilene results in increased methylation of GSG1L intron

NCBI chr 1:189,871,034...190,084,947
Ensembl chr 1:189,871,034...190,084,947

G

glycogen synthase kinase 3 beta

increases expression

EXP

Methapyrilene results in increased expression of GSK3B mRNA

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249

G

glutathione-disulfide reductase

increases expression

EXP

Methapyrilene results in increased expression of GSR mRNA

PMID:15890375 PMID:28935588

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione synthetase

increases expression

EXP

Methapyrilene results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306

G

glutathione S-transferase alpha 2

increases expression

EXP

Methapyrilene results in increased expression of GSTA2 mRNA

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase alpha 4

increases expression

EXP

Methapyrilene results in increased expression of GSTA4 mRNA

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488

G

glutathione S-transferase alpha 5

increases expression

EXP

Methapyrilene results in increased expression of GSTA5 mRNA

NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765

G

glutathione S-transferase mu 2

decreases expression

EXP

Methapyrilene results in decreased expression of GSTM2 mRNA

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase pi 1

increases expression

EXP

Methapyrilene results in increased expression of GSTP1 mRNA

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase, theta 3

decreases expression

EXP

Methapyrilene results in decreased expression of GSTT3 mRNA

NCBI chr20:12,873,618...12,881,974
Ensembl chr20:12,874,374...12,881,973

G

general transcription factor 2A subunit 1 like

increases methylation

ISO

Methapyrilene results in increased methylation of GTF2A1L intron

NCBI chr 6:11,506,362...11,591,622
Ensembl chr 6:11,506,363...11,565,862

G

general transcription factor II I

decreases expression

EXP

Methapyrilene results in decreased expression of GTF2I mRNA

NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677

G

GTF2I repeat domain containing 1

affects methylation

ISO

Methapyrilene affects the methylation of GTF2IRD1 intron

NCBI chr12:27,890,594...27,997,506
Ensembl chr12:27,890,675...27,997,494

G

general transcription factor IIIC subunit 2

decreases expression

EXP

Methapyrilene results in decreased expression of GTF3C2 mRNA

NCBI chr 6:30,913,263...30,941,305
Ensembl chr 6:30,923,106...30,940,465

G

general transcription factor IIIC subunit 3

decreases expression

EXP

Methapyrilene results in decreased expression of GTF3C3 mRNA

NCBI chr 9:63,375,860...63,437,475
Ensembl chr 9:63,375,874...63,437,413

G

GTP binding protein 10

decreases expression

EXP

Methapyrilene results in decreased expression of GTPBP10 mRNA

NCBI chr 4:29,431,683...29,449,201
Ensembl chr 4:29,431,692...29,449,212

G

GTP binding protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of GTPBP2 mRNA

NCBI chr 9:22,311,532...22,321,405
Ensembl chr 9:22,311,158...22,321,441

G

G-2 and S-phase expressed 1

increases expression

EXP

Methapyrilene results in increased expression of GTSE1 mRNA

NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:118,829,903...118,846,661

G

guanylate cyclase 1 soluble subunit alpha 2

increases methylation

ISO

Methapyrilene results in increased methylation of GUCY1A2 intron

NCBI chr 8:8,785,212...9,174,322
Ensembl chr 8:8,785,121...9,174,272

G

guanylate cyclase 2C

decreases methylation

ISO

Methapyrilene results in decreased methylation of GUCY2C intron

NCBI chr 4:171,299,715...171,380,296
Ensembl chr 4:171,299,740...171,380,296

G

guanylate cyclase 2E

increases methylation

ISO

Methapyrilene results in increased methylation of GUCY2D intron

NCBI chr10:54,453,753...54,478,639
Ensembl chr10:54,457,844...54,472,898

G

gulonolactone (L-) oxidase

decreases expression

EXP

Methapyrilene results in decreased expression of GULO mRNA

NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422

G

glycogen synthase 2

decreases expression

EXP

Methapyrilene results in decreased expression of GYS2 mRNA

PMID:16393664 PMID:30467583

NCBI chr 4:177,096,063...177,137,236
Ensembl chr 4:177,096,063...177,137,236

G

H1.0 linker histone

decreases expression

EXP

Methapyrilene results in decreased expression of H1F0 mRNA

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006

G

H2A.X variant histone

increases methylation
increases expression

ISO
EXP

Methapyrilene results in increased methylation of H2AX polyA tail
Methapyrilene results in increased expression of H2AX mRNA

PMID:15890375 PMID:30157460

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

H2A.Z variant histone 1

increases expression

EXP

Methapyrilene results in increased expression of H2AZ1 mRNA

NCBI chr 2:229,026,464...229,031,411
Ensembl chr 2:229,028,843...229,031,411

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of H6PD mRNA
Methapyrilene results in increased methylation of H6PD intron

PMID:30157460 PMID:30467583

NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125

G

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

decreases expression

EXP

Methapyrilene results in decreased expression of HACE1 mRNA

NCBI chr20:50,618,004...50,733,460
Ensembl chr20:50,618,004...50,733,466

G

2-hydroxyacyl-CoA lyase 1

decreases expression

EXP

Methapyrilene results in decreased expression of HACL1 mRNA

NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,833,268...6,869,410

G

hydroxyacyl-CoA dehydrogenase

decreases expression

EXP

Methapyrilene results in decreased expression of HADH mRNA

NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of HADHA mRNA

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

histidine ammonia lyase

decreases expression

EXP

Methapyrilene results in decreased expression of HAL mRNA

NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744

G

hepcidin antimicrobial peptide

increases expression

ISO

Methapyrilene results in increased expression of HAMP mRNA

NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297

G

hydroxyacid oxidase 2

decreases expression

ISO
EXP

Methapyrilene results in decreased expression of HAO2 mRNA

NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133

G

HAUS augmin-like complex, subunit 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of HAUS7 intron

NCBI chr X:156,306,320...156,331,940
Ensembl chr X:156,306,320...156,352,158

G

HAUS augmin-like complex, subunit 8

increases methylation

ISO

Methapyrilene results in increased methylation of HAUS8 intron

NCBI chr16:17,964,813...17,979,313
Ensembl chr16:17,964,814...17,979,192

G

host cell factor C2

decreases expression

EXP

Methapyrilene results in decreased expression of HCFC2 mRNA

NCBI chr 7:22,875,440...22,907,391
Ensembl chr 7:22,864,278...22,907,322

G

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

affects methylation

ISO

Methapyrilene affects the methylation of HCN4 intron

NCBI chr 8:68,118,062...68,155,482
Ensembl chr 8:68,118,062...68,155,495

G

histone deacetylase 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of HDAC4 intron

NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:99,955,116...100,197,637

G

histone deacetylase 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of HDAC9 intron

NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:56,490,988...57,351,835

G

histidine decarboxylase

increases expression

EXP

Methapyrilene results in increased expression of HDC mRNA

NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711

G

HD domain containing 3

decreases expression

EXP

Methapyrilene results in decreased expression of HDDC3 mRNA

NCBI chr 1:143,708,703...143,711,010
Ensembl chr 1:143,705,320...143,711,010

G

haloacid dehalogenase-like hydrolase domain containing 3

decreases expression

EXP

Methapyrilene results in decreased expression of HDHD3 mRNA

NCBI chr 5:80,966,878...80,970,345
Ensembl chr 5:80,954,610...80,970,854

G

HEAT repeat containing 5B

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of HEATR5B mRNA
Methapyrilene results in increased methylation of HEATR5B exon

PMID:30157460 PMID:30467583

NCBI chr 6:21,995,558...22,075,582
Ensembl chr 6:21,995,602...22,075,582

G

HECT domain E3 ubiquitin protein ligase 1

decreases expression

EXP

Methapyrilene results in decreased expression of HECTD1 mRNA

NCBI chr 6:74,916,803...75,003,408
Ensembl chr 6:74,916,803...75,003,408

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of HECW1 intron

NCBI chr17:55,366,904...55,780,028
Ensembl chr17:55,366,657...55,776,212

G

helicase with zinc finger

increases methylation

ISO

Methapyrilene results in increased methylation of HELZ intron

NCBI chr10:92,979,039...93,144,868
Ensembl chr10:92,999,733...93,138,075

G

helicase with zinc finger 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of HELZ2 promoter

NCBI chr 3:188,716,370...188,730,776
Ensembl chr 3:188,716,370...188,730,716

G

HECT and RLD domain containing E3 ubiquitin protein ligase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of HERC3 exon

NCBI chr 4:89,282,374...89,372,656
Ensembl chr 4:89,282,445...89,372,652

G

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

decreases expression

EXP

Methapyrilene results in decreased expression of HERC6 mRNA

NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993

G

homocysteine inducible ER protein with ubiquitin like domain 1

decreases expression

EXP

Methapyrilene results in decreased expression of HERPUD1 mRNA

NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081

G

HEXIM P-TEFb complex subunit 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of HEXIM2 intron

NCBI chr10:88,572,102...88,584,856
Ensembl chr10:88,578,996...88,584,855

G

hepatocyte growth factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of HGF intron

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851

G

3-hydroxyisobutyrate dehydrogenase

decreases expression

EXP

Methapyrilene results in decreased expression of HIBADH mRNA

NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242

G

3-hydroxyisobutyryl-CoA hydrolase

decreases expression

EXP

Methapyrilene results in decreased expression of HIBCH mRNA; Methapyrilene results in decreased expression of HIBCH protein

NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886

G

hypoxia inducible factor 1 subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of HIF1A mRNA

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

HIG1 hypoxia inducible domain family, member 1A

increases expression

EXP

Methapyrilene results in increased expression of HIGD1A mRNA

NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888

G

histidine triad nucleotide binding protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of HINT3 mRNA

NCBI chr 1:28,854,860...28,864,723
Ensembl chr 1:28,854,844...28,867,125

G

huntingtin interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of HIP1 intron

NCBI chr12:26,769,868...26,904,367
Ensembl chr12:26,769,961...26,904,296

G

homeodomain interacting protein kinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of HIPK1 mRNA

NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:193,937,261...193,975,164

G

homeodomain interacting protein kinase 2

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of HIPK2 mRNA
Methapyrilene results in decreased methylation of HIPK2 intron

PMID:30157460 PMID:30467583

NCBI chr 4:68,399,358...68,586,404
Ensembl chr 4:68,369,099...68,586,108

G

HIRA interacting protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of HIRIP3 mRNA

NCBI chr 1:190,903,065...190,905,610
Ensembl chr 1:190,902,593...190,905,607

G

HIVEP zinc finger 3

increases methylation

ISO

Methapyrilene results in increased methylation of HIVEP3 intron

NCBI chr 5:138,610,592...139,013,058
Ensembl chr 5:138,943,312...139,010,430

G

hemojuvelin BMP co-receptor

decreases expression

EXP

Methapyrilene results in decreased expression of HJV mRNA

NCBI chr 2:186,754,801...186,758,708
Ensembl chr 2:186,754,811...186,758,867

G

hexokinase 1

affects expression

EXP

Methapyrilene affects the expression of HK1 mRNA

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814

G

hexokinase 3

decreases expression

EXP

Methapyrilene results in decreased expression of HK3 mRNA

NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,605,016...9,620,037

G

holocarboxylase synthetase

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of HLCS intron
Methapyrilene results in decreased expression of HLCS mRNA

PMID:30157460 PMID:30467583

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

histocompatibility minor 13

decreases methylation

ISO

Methapyrilene results in decreased methylation of HM13 intron

NCBI chr 3:161,606,059...161,641,382
Ensembl chr 3:161,606,052...161,644,805

G

hydroxymethylbilane synthase

decreases expression

EXP

Methapyrilene results in decreased expression of HMBS mRNA

NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:53,570,364...53,577,802

G

hemicentin 1

increases methylation

ISO

Methapyrilene results in increased methylation of HMCN1 intron

NCBI chr13:65,165,532...65,634,681
Ensembl chr13:65,165,532...65,634,519

G

hemicentin 2

increases methylation

ISO

Methapyrilene results in increased methylation of HMCN2 intron

NCBI chr 3:34,986,246...35,136,047
Ensembl chr 3:34,986,263...35,136,106

G

high mobility group box 2

increases expression

EXP

Methapyrilene results in increased expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression
increases expression

EXP

Methapyrilene results in decreased expression of HMGCS2 mRNA
Methapyrilene results in increased expression of HMGCS2 protein

PMID:16393664 PMID:30467583

NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242

G

heme oxygenase 1

increases expression

EXP

Methapyrilene results in increased expression of HMOX1 mRNA; Methapyrilene results in increased expression of HMOX1 protein

PMID:15890375 PMID:16393664 PMID:19523481

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heme oxygenase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of HMOX2 intron

NCBI chr10:11,303,512...11,337,640
Ensembl chr10:11,303,512...11,318,800

G

H6 family homeobox 1

increases methylation

ISO

Methapyrilene results in increased methylation of HMX1 intron; Methapyrilene results in increased methylation of HMX1 polyA tail

NCBI chr14:79,585,840...79,589,626
Ensembl chr14:79,585,840...79,589,626

G

HNF1 homeobox A

decreases expression

EXP

Methapyrilene results in decreased expression of HNF1A mRNA

NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755

G

hepatocyte nuclear factor 4, alpha

multiple interactions
decreases expression

ISO
EXP

Methapyrilene inhibits the reaction [HNF4A protein binds to TF promoter]
Methapyrilene results in decreased expression of HNF4A protein
Methapyrilene results in decreased expression of HNF4A mRNA

PMID:28935588 PMID:30467583

NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758

G

heterogeneous nuclear ribonucleoprotein A0

decreases expression

EXP

Methapyrilene results in decreased expression of HNRNPA0 mRNA

NCBI chr17:6,513,129...6,515,786
Ensembl chr17:6,512,629...6,516,127

G

heterogeneous nuclear ribonucleoprotein A3

decreases expression

EXP

Methapyrilene results in decreased expression of HNRNPA3 mRNA

NCBI chr 3:80,984,470...80,999,413
Ensembl chr 3:80,985,969...80,996,043

G

heterogeneous nuclear ribonucleoprotein K

decreases expression

EXP

Methapyrilene results in decreased expression of HNRNPK mRNA

NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565

G

heterogeneous nuclear ribonucleoprotein M

decreases methylation

ISO

Methapyrilene results in decreased methylation of HNRNPM polyA tail

NCBI chr 7:15,140,877...15,178,871
Ensembl chr 7:15,129,287...15,178,871

G

heterogeneous nuclear ribonucleoprotein R

decreases expression

EXP

Methapyrilene results in decreased expression of HNRNPR mRNA

NCBI chr 5:153,826,482...153,872,272
Ensembl chr 5:153,826,692...153,858,344

G

heterogeneous nuclear ribonucleoprotein U

decreases expression

EXP

Methapyrilene results in decreased expression of HNRNPU mRNA

NCBI chr13:92,609,791...92,618,580
Ensembl chr13:92,605,216...92,618,612

G

hook microtubule-tethering protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of HOOK2 intron

NCBI chr19:40,056,732...40,075,027
Ensembl chr19:40,056,732...40,081,270

G

hook microtubule-tethering protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of HOOK3 mRNA

NCBI chr16:72,656,929...72,751,696
Ensembl chr16:72,657,019...72,764,071

G

homeo box C12

increases methylation

ISO

Methapyrilene results in increased methylation of HOXC12 exon

NCBI chr 7:135,952,682...135,954,280
Ensembl chr 7:135,952,682...135,954,280

G

heterochromatin protein 1, binding protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of HP1BP3 mRNA

NCBI chr 5:155,719,109...155,746,329
Ensembl chr 5:155,719,115...155,746,325

G

hippocalcin-like 1

increases methylation

ISO

Methapyrilene results in increased methylation of HPCAL1 intron

NCBI chr 6:46,206,809...46,313,364
Ensembl chr 6:46,260,494...46,313,353

G

4-hydroxyphenylpyruvate dioxygenase

decreases methylation

ISO

Methapyrilene results in decreased methylation of HPD intron

NCBI chr12:39,042,246...39,053,596
Ensembl chr12:39,042,238...39,053,612

G

hepsin

decreases expression

EXP

Methapyrilene results in decreased expression of HPN mRNA

NCBI chr 1:95,464,468...95,480,169
Ensembl chr 1:95,464,470...95,480,199

G

hypoxanthine phosphoribosyltransferase 1

increases expression

EXP

Methapyrilene results in increased expression of HPRT1 mRNA

NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712

G

heparanase 2 (inactive)

increases methylation

ISO

Methapyrilene results in increased methylation of HPSE2 intron

NCBI chr 1:251,532,149...252,231,316
Ensembl chr 1:251,532,149...252,195,255

G

HRas proto-oncogene, GTPase

increases expression

EXP

Methapyrilene results in increased expression of HRAS mRNA

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590

G

heparan sulfate-glucosamine 3-sulfotransferase 3B1

decreases methylation

ISO

Methapyrilene results in decreased methylation of HS3ST3B1 intron

NCBI chr10:49,060,693...49,093,185
Ensembl chr10:49,060,693...49,093,185

G

heparan sulfate 6-O-sulfotransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of HS6ST1 intron

NCBI chr 9:45,779,402...45,818,583
Ensembl chr 9:45,779,019...45,818,582

G

hydroxysteroid (17-beta) dehydrogenase 14

increases methylation

ISO

Methapyrilene results in increased methylation of HSD17B14 intron

NCBI chr 1:105,165,695...105,176,045
Ensembl chr 1:105,165,695...105,176,510

G

hydroxysteroid (17-beta) dehydrogenase 4

decreases expression

EXP

Methapyrilene results in decreased expression of HSD17B4 mRNA

NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467

G

hydroxysteroid (17-beta) dehydrogenase 6

increases methylation

ISO

Methapyrilene results in increased methylation of HSD17B6 intron

NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5

decreases expression

EXP

Methapyrilene results in decreased expression of HSD3B5 mRNA

NCBI chr 2:188,697,669...188,717,141
Ensembl chr 2:188,697,670...188,709,118

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of HSD3B7 intron
Methapyrilene results in decreased expression of HSD3B7 mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:191,842,688...191,845,919
Ensembl chr 1:191,842,636...191,845,921

G

heat shock transcription factor 1

increases expression

EXP

Methapyrilene results in increased expression of HSF1 mRNA

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665

G

hematopoietic SH2 domain containing

decreases methylation

ISO

Methapyrilene results in decreased methylation of HSH2D polyA tail

NCBI chr16:17,664,548...17,686,976
Ensembl chr16:17,669,345...17,682,013

G

heat shock protein 90 beta family member 1

decreases expression

EXP

Methapyrilene results in decreased expression of HSP90B1 mRNA

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293

G

heat shock protein family A (Hsp70) member 12A

decreases methylation

ISO

Methapyrilene results in decreased methylation of HSPA12A intron

NCBI chr 1:267,921,780...268,083,171
Ensembl chr 1:267,921,782...268,082,794

G

heat shock protein family A (Hsp70) member 13

decreases expression

EXP

Methapyrilene results in decreased expression of HSPA13 mRNA

NCBI chr11:27,862,717...27,876,898
Ensembl chr11:27,862,593...27,876,898

G

heat shock protein family A (Hsp70) member 5

increases expression

EXP

Methapyrilene results in increased expression of HSPA5 mRNA

PMID:15120968 PMID:17450226

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 8

increases expression

EXP

Methapyrilene results in increased expression of HSPA8 protein

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family A (Hsp70) member 9

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of HSPA9 mRNA
Methapyrilene results in decreased expression of HSPA9 protein

PMID:15890375 PMID:17450226 PMID:22484513 PMID:30467583

NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398

G

heat shock protein family B (small) member 1

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of HSPB1 mRNA
Methapyrilene results in decreased expression of HSPB1 mRNA

PMID:15890375 PMID:16393664 PMID:30467583

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heat shock protein family D (Hsp60) member 1

increases expression

EXP

Methapyrilene results in increased expression of HSPD1 protein

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037

G

heat shock protein family E (Hsp10) member 1

increases expression

EXP

Methapyrilene results in increased expression of HSPE1 mRNA

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

heat shock protein family H (Hsp110) member 1

increases expression

EXP

Methapyrilene results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891

G

HtrA serine peptidase 3

increases methylation

ISO

Methapyrilene results in increased methylation of HTRA3 intron

NCBI chr14:79,293,535...79,321,936
Ensembl chr14:79,293,541...79,321,936

G

hormonally upregulated Neu-associated kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of HUNK promoter

NCBI chr11:43,127,244...43,244,502
Ensembl chr11:43,127,244...43,244,502

G

HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of HUWE1 exon

NCBI chr X:24,350,708...24,480,798
Ensembl chr X:24,353,217...24,480,798

G

hyccin PI4KA lipid kinase complex subunit 2

decreases expression

EXP

Methapyrilene results in decreased expression of HYCC2 mRNA

NCBI chr 9:67,551,064...67,623,353
Ensembl chr 9:67,551,064...67,587,186

G

Hydin, axonemal central pair apparatus protein

affects methylation

ISO

Methapyrilene affects the methylation of HYDIN intron

NCBI chr19:55,146,382...55,492,660
Ensembl chr19:55,146,466...55,492,660

G

isoleucyl-tRNA synthetase 1

decreases expression

EXP

Methapyrilene results in decreased expression of IARS1 mRNA

NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652

G

inhibitor of Bruton tyrosine kinase

decreases expression

EXP

Methapyrilene results in decreased expression of IBTK mRNA

NCBI chr 8:95,505,630...95,579,435
Ensembl chr 8:95,505,630...95,578,301

G

intercellular adhesion molecule 1

increases expression

EXP
ISO

Methapyrilene results in increased expression of ICAM1 mRNA

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

intercellular adhesion molecule 2

increases methylation

ISO

Methapyrilene results in increased methylation of ICAM2 polyA tail

NCBI chr10:91,808,449...91,819,319
Ensembl chr10:91,808,316...91,815,072

G

insulin degrading enzyme

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of IDE mRNA
Methapyrilene results in decreased expression of IDE mRNA

PMID:15890375 PMID:30467583

NCBI chr 1:244,415,495...244,516,925
Ensembl chr 1:244,416,343...244,514,526

G

isocitrate dehydrogenase (NADP(+)) 2

decreases expression

EXP

Methapyrilene results in decreased expression of IDH2 mRNA

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

increases methylation

ISO

Methapyrilene results in increased methylation of IDH3G polyA tail

NCBI chr X:156,666,573...156,675,482
Ensembl chr X:156,666,577...156,675,799

G

isopentenyl-diphosphate delta isomerase 1

increases expression

EXP

Methapyrilene results in increased expression of IDI1 mRNA

NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524

G

iduronate 2-sulfatase

decreases expression

EXP

Methapyrilene results in decreased expression of IDS mRNA

NCBI chr X:154,070,781...154,093,681
Ensembl chr X:154,070,781...154,091,444

G

immediate early response 3 interacting protein 1, pseudogene 1

increases methylation

ISO

Methapyrilene results in increased methylation of IER3IP1 promoter

NCBI chr 4:133,898,662...133,899,156
Ensembl chr 4:133,887,903...133,898,847

G

immediate early response 5

increases expression

EXP

Methapyrilene results in increased expression of IER5 mRNA

NCBI chr13:69,820,450...69,822,542
Ensembl chr13:69,820,451...69,822,543

G

IFI30, lysosomal thiol reductase

decreases methylation

ISO

Methapyrilene results in decreased methylation of IFI30 intron

NCBI chr16:18,709,570...18,713,635
Ensembl chr16:18,709,563...18,715,711

G

interferon-induced protein 35

decreases expression

EXP

Methapyrilene results in decreased expression of IFI35 mRNA

NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750

G

interferon-induced protein with tetratricopeptide repeats 2

decreases expression

EXP

Methapyrilene results in decreased expression of IFIT2 mRNA

NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798

G

interferon induced transmembrane protein 1

increases expression

EXP

Methapyrilene results in increased expression of IFITM1 mRNA

NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776

G

interferon alpha and beta receptor subunit 1

decreases expression

EXP

Methapyrilene results in decreased expression of IFNAR1 mRNA

NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205

G

interferon gamma

increases expression

EXP

Methapyrilene results in increased expression of IFNG protein

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interferon gamma receptor 2

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of IFNGR2 intron
Methapyrilene results in decreased methylation of IFNGR2 promoter

NCBI chr11:44,265,703...44,283,975
Ensembl chr11:44,265,703...44,283,975

G

interferon-related developmental regulator 1

increases expression

EXP

Methapyrilene results in increased expression of IFRD1 mRNA

PMID:18619722 PMID:22484513

NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131

G

intraflagellar transport 140

increases methylation

ISO

Methapyrilene results in increased methylation of IFT140 intron

NCBI chr10:14,537,134...14,624,926
Ensembl chr10:14,537,466...14,624,926

G

intraflagellar transport 46

decreases expression

EXP

Methapyrilene results in decreased expression of IFT46 mRNA

NCBI chr 8:53,975,085...54,000,837
Ensembl chr 8:53,984,242...54,000,836

G

immunoglobulin superfamily, DCC subclass, member 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of IGDCC4 intron

NCBI chr 8:74,517,082...74,552,834
Ensembl chr 8:74,517,086...74,552,834

G

insulin-like growth factor 2 mRNA binding protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of IGF2BP3 intron

NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730

G

insulin-like growth factor binding protein, acid labile subunit

decreases expression

EXP

Methapyrilene results in decreased expression of IGFALS mRNA

NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138

G

insulin-like growth factor binding protein 1

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of IGFBP1 mRNA
Methapyrilene results in decreased expression of IGFBP1 mRNA

PMID:15120968 PMID:15890375 PMID:30467583

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344

G

insulin-like growth factor binding protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of IGFBP2 intron

NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171

G

insulin-like growth factor binding protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of IGFBP3 mRNA

NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944

G

immunoglobulin-like and fibronectin type III domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of IGFN1 intron

NCBI chr13:49,947,330...49,979,203
Ensembl chr13:49,947,330...49,989,601

G

immunoglobulin superfamily, member 11

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of IGSF11 mRNA
Methapyrilene results in increased methylation of IGSF11 exon; Methapyrilene results in increased methylation of IGSF11 intron

PMID:30157460 PMID:30467583

NCBI chr11:75,238,706...75,389,748
Ensembl chr11:75,236,545...75,390,425

G

immunoglobin superfamily, member 21

decreases methylation

ISO

Methapyrilene results in decreased methylation of IGSF21 intron

NCBI chr 5:157,570,964...157,795,290
Ensembl chr 5:157,570,964...157,795,290

G

immunoglobulin superfamily, member 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of IGSF9 exon; Methapyrilene results in decreased methylation of IGSF9 promoter

NCBI chr13:87,480,979...87,497,974
Ensembl chr13:87,481,279...87,497,974

G

immunoglobulin superfamily, member 9B

increases methylation

ISO

Methapyrilene results in increased methylation of IGSF9B intron

NCBI chr 8:33,971,779...34,027,390
Ensembl chr 8:33,971,779...34,018,128

G

inhibitor of nuclear factor kappa B kinase subunit beta

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of IKBKB mRNA
Methapyrilene results in decreased methylation of IKBKB intron

PMID:30157460 PMID:30467583

NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911

G

interleukin 10

decreases expression

EXP

Methapyrilene results in decreased expression of IL10 protein

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 10 receptor subunit alpha

increases methylation

ISO

Methapyrilene results in increased methylation of IL10RA intron

NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028

G

interleukin 12B

increases expression

EXP

Methapyrilene results in increased expression of IL12B protein

NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194

G

interleukin 12 receptor subunit beta 1

increases methylation

ISO

Methapyrilene results in increased methylation of IL12RB1 promoter

NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,654,207...18,666,824

G

interleukin 17 receptor D

increases methylation

ISO

Methapyrilene results in increased methylation of IL17RD intron

NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850

G

interleukin 18 receptor 1

increases methylation

ISO

Methapyrilene results in increased methylation of IL18R1 intron

NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367

G

interleukin 1 alpha

increases expression

EXP

Methapyrilene results in increased expression of IL1A protein

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

increases expression

EXP

Methapyrilene results in increased expression of IL1B mRNA; Methapyrilene results in increased expression of IL1B protein

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor accessory protein

increases methylation

ISO

Methapyrilene results in increased methylation of IL1RAP intron

NCBI chr11:87,567,813...87,704,346
Ensembl chr11:87,575,116...87,704,342

G

interleukin 1 receptor accessory protein-like 1

increases methylation

ISO

Methapyrilene results in increased methylation of IL1RAPL1 intron

NCBI chr X:55,322,779...56,827,486
Ensembl chr X:55,328,964...56,826,613

G

interleukin 1 receptor-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of IL1RL1 protein

NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891

G

interleukin 1 receptor antagonist

increases expression

EXP

Methapyrilene results in increased expression of IL1RN mRNA

NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732

G

interleukin 2 receptor subunit beta

increases methylation

ISO

Methapyrilene results in increased methylation of IL2RB 3' UTR

NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:111,913,828...111,928,537

G

interleukin 4 induced 1

increases methylation

ISO

Methapyrilene results in increased methylation of IL4I1 intron

NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:104,435,981...104,461,053

G

interleukin 4 receptor

increases methylation

ISO

Methapyrilene results in increased methylation of IL4R intron

NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636

G

interleukin 6

decreases expression

EXP

Methapyrilene results in decreased expression of IL6 protein

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

interleukin 6 receptor

increases methylation

ISO

Methapyrilene results in increased methylation of IL6R intron

NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221

G

interleukin 6 cytokine family signal transducer

decreases expression

EXP

Methapyrilene results in decreased expression of IL6ST mRNA

NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182

G

interleukin 7

decreases expression

ISO

Methapyrilene results in decreased expression of IL7 mRNA

NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389

G

ilvB acetolactate synthase like

decreases methylation

ISO

Methapyrilene results in decreased methylation of HACL2 intron

NCBI chr 7:11,690,445...11,700,498
Ensembl chr 7:11,690,445...11,700,498

G

inner mitochondrial membrane peptidase subunit 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of IMMP2L intron

NCBI chr 6:63,797,189...64,696,906
Ensembl chr 6:63,797,237...64,697,749

G

inhibitor of growth family, member 1

increases expression

EXP

Methapyrilene results in increased expression of ING1 mRNA

NCBI chr16:84,639,378...84,649,498
Ensembl chr16:84,639,381...84,647,616

G

inhibin subunit beta E

decreases expression

EXP

Methapyrilene results in decreased expression of INHBE mRNA

NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519

G

inositol polyphosphate-4-phosphatase type I A

increases methylation

ISO

Methapyrilene results in increased methylation of INPP4A intron

NCBI chr 9:47,024,064...47,142,391
Ensembl chr 9:47,087,471...47,135,968

G

inositol polyphosphate-5-phosphatase A

affects methylation

ISO

Methapyrilene affects the methylation of INPP5A intron

NCBI chr 1:203,619,676...203,810,035
Ensembl chr 1:203,619,637...203,810,028

G

inositol polyphosphate-5-phosphatase D

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of INPP5D intron
Methapyrilene results in decreased methylation of INPP5D exon

NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589

G

insulin induced gene 2

decreases expression

EXP

Methapyrilene results in decreased expression of INSIG2 mRNA

NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658

G

insulin receptor

affects methylation
decreases methylation
decreases expression

ISO
EXP

Methapyrilene affects the methylation of INSR intron
Methapyrilene results in decreased methylation of INSR exon
Methapyrilene results in decreased expression of INSR mRNA

PMID:30157460 PMID:30467583

NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803

G

inhibitory synaptic factor family member 2B

increases methylation

ISO

Methapyrilene results in increased methylation of INSYN2B intron

NCBI chr10:19,420,561...19,528,006
Ensembl chr10:19,507,084...19,511,298

G

integrator complex subunit 6

increases expression

EXP

Methapyrilene results in increased expression of INTS6 mRNA

NCBI chr15:41,080,584...41,224,350
Ensembl chr15:41,109,125...41,197,519

G

integrator complex subunit 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of INTS7 intron

NCBI chr13:105,686,208...105,739,609
Ensembl chr13:105,686,128...105,739,608

G

integrator complex subunit 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of INTS8 intron

NCBI chr 5:29,094,475...29,141,874
Ensembl chr 5:29,094,475...29,142,099

G

integrator complex subunit 9

increases methylation

ISO

Methapyrilene results in increased methylation of INTS9 intron

NCBI chr15:43,376,235...43,460,549
Ensembl chr15:43,375,850...43,478,936

G

importin 4

increases expression
decreases methylation

EXP
ISO

Methapyrilene results in increased expression of IPO4 mRNA
Methapyrilene results in decreased methylation of IPO4 promoter

PMID:28935588 PMID:30157460

NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241

G

importin 7

increases methylation

ISO

Methapyrilene results in increased methylation of IPO7 promoter

NCBI chr 1:173,497,472...173,537,707
Ensembl chr 1:173,497,503...173,536,778

G

inositol-pentakisphosphate 2-kinase

increases methylation

ISO

Methapyrilene results in increased methylation of IPPK promoter

NCBI chr17:15,396,691...15,441,648
Ensembl chr17:15,395,168...15,436,000

G

IQ motif containing with AAA domain 1

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of DRC11 promoter
Methapyrilene results in decreased methylation of DRC11 intron

NCBI chr 9:98,074,389...98,190,233
Ensembl chr 9:98,073,887...98,190,066

G

IQ motif containing E

decreases methylation

ISO

Methapyrilene results in decreased methylation of IQCE intron

NCBI chr12:19,057,060...19,096,626
Ensembl chr12:19,056,307...19,096,624

G

IQ motif containing G

increases methylation

ISO

Methapyrilene results in increased methylation of DRC9 intron

NCBI chr11:81,235,204...81,276,249
Ensembl chr11:81,235,090...81,276,249

G

IQ motif containing GTPase activating protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of IQGAP3 intron

NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797

G

IQ motif and Sec7 domain ArfGEF 1

increases methylation

ISO

Methapyrilene results in increased methylation of IQSEC1 intron

NCBI chr 4:124,725,917...125,045,351
Ensembl chr 4:124,725,917...125,045,550

G

IQ motif and Sec7 domain ArfGEF 3

increases methylation

ISO

Methapyrilene results in increased methylation of IQSEC3 exon

NCBI chr 4:156,283,040...156,379,396
Ensembl chr 4:156,283,043...156,379,396

G

iron responsive element binding protein 2

affects expression
decreases expression

ISO
EXP

Methapyrilene affects the expression of IREB2 mRNA
Methapyrilene results in decreased expression of IREB2 mRNA

PMID:28935588 PMID:30467583

NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520

G

interferon regulatory factor 2

increases methylation

ISO

Methapyrilene results in increased methylation of IRF2 intron

NCBI chr16:52,171,855...52,283,620
Ensembl chr16:52,164,442...52,282,627

G

interferon regulatory factor 2 binding protein-like

decreases expression

EXP

Methapyrilene results in decreased expression of IRF2BPL mRNA

NCBI chr 6:112,258,149...112,262,264
Ensembl chr 6:112,258,188...112,263,280

G

interferon regulatory factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of IRF3 promoter

NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401

G

interferon regulatory factor 9

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of IRF9 mRNA
Methapyrilene results in decreased methylation of IRF9 exon

PMID:30157460 PMID:30467583

NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879

G

immunity related GTPase cinema

decreases methylation

ISO

Methapyrilene results in decreased methylation of IRGC promoter

NCBI chr 1:89,148,056...89,151,838
Ensembl chr 1:89,147,624...89,153,921

G

insulin receptor substrate 2

decreases expression

EXP

Methapyrilene results in decreased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543

G

immunoglobulin superfamily containing leucine-rich repeat 2

increases methylation

ISO

Methapyrilene results in increased methylation of ISLR2 intron

NCBI chr 8:67,504,042...67,512,125
Ensembl chr 8:67,504,037...67,513,708

G

isthmin 1

increases methylation

ISO

Methapyrilene results in increased methylation of ISM1 intron

NCBI chr 3:147,476,983...147,555,900
Ensembl chr 3:147,475,533...147,555,908

G

isthmin 2

increases methylation

ISO

Methapyrilene results in increased methylation of ISM2 intron

NCBI chr 6:112,652,772...112,675,098
Ensembl chr 6:112,657,122...112,675,295

G

isochorismatase domain containing 2b

increases methylation

ISO

Methapyrilene results in increased methylation of ISOC2 intron

NCBI chr 1:78,001,735...78,022,565
Ensembl chr 1:78,001,735...78,022,564

G

integrin subunit alpha 11

decreases methylation

ISO

Methapyrilene results in decreased methylation of ITGA11 intron

NCBI chr 8:72,041,432...72,150,137
Ensembl chr 8:72,016,652...72,150,137

G

integrin subunit alpha 2b

increases methylation

ISO

Methapyrilene results in increased methylation of ITGA2B intron

NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833

G

integrin subunit alpha 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of ITGA3 intron

NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901

G

integrin subunit alpha 5

increases methylation

ISO

Methapyrilene results in increased methylation of ITGA5 intron

NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305

G

integrin subunit alpha 6

increases methylation

ISO

Methapyrilene results in increased methylation of ITGA6 intron

NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076

G

integrin subunit alpha 9

increases methylation

ISO

Methapyrilene results in increased methylation of ITGA9 intron

NCBI chr 8:127,185,244...127,493,296
Ensembl chr 8:127,169,226...127,493,296

G

integrin subunit alpha D

increases methylation

ISO

Methapyrilene results in increased methylation of ITGAD intron

NCBI chr 1:192,190,204...192,218,864
Ensembl chr 1:192,190,204...192,218,864

G

integrin subunit alpha E

decreases methylation

ISO

Methapyrilene results in decreased methylation of ITGAE intron

NCBI chr10:58,203,331...58,262,606
Ensembl chr10:58,203,364...58,262,606

G

inter-alpha-trypsin inhibitor heavy chain 4

increases expression

EXP

Methapyrilene results in increased expression of ITIH4 mRNA

NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160

G

inter-alpha-trypsin inhibitor heavy chain 5

increases methylation

ISO

Methapyrilene results in increased methylation of ITIH5 polyA tail

NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496

G

IL2-inducible T-cell kinase

increases methylation

EXP

Methapyrilene results in increased methylation of ITK gene

NCBI chr10:31,254,667...31,316,004
Ensembl chr10:31,254,667...31,316,004

G

inositol-tetrakisphosphate 1-kinase

affects methylation

ISO

Methapyrilene affects the methylation of ITPK1 intron

NCBI chr 6:127,475,589...127,609,320
Ensembl chr 6:127,476,808...127,609,062

G

inositol-trisphosphate 3-kinase A

increases methylation

ISO

Methapyrilene results in increased methylation of ITPKA polyA tail

NCBI chr 3:127,179,841...127,188,405
Ensembl chr 3:127,179,808...127,188,414

G

inositol-trisphosphate 3-kinase B

increases methylation

ISO

Methapyrilene results in increased methylation of ITPKB exon

NCBI chr13:94,601,072...94,696,180
Ensembl chr13:94,601,167...94,696,179

G

inositol 1,4,5-trisphosphate receptor, type 1

decreases expression

EXP

Methapyrilene results in decreased expression of ITPR1 mRNA

NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504

G

inositol 1,4,5-trisphosphate receptor, type 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of ITPR2 intron

NCBI chr 4:180,759,325...181,165,361
Ensembl chr 4:180,760,442...181,164,763

G

intersectin 1

increases methylation

ISO

Methapyrilene results in increased methylation of ITSN1 intron

NCBI chr11:44,464,515...44,646,598
Ensembl chr11:44,513,186...44,646,598

G

intersectin 2

decreases expression

EXP

Methapyrilene results in decreased expression of ITSN2 mRNA

NCBI chr 6:33,336,086...33,446,818
Ensembl chr 6:33,336,441...33,446,818

G

isovaleryl-CoA dehydrogenase

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of IVD mRNA
Methapyrilene results in increased methylation of IVD intron

PMID:30157460 PMID:30467583

NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160

G

interacts with SUPT6H, CTD assembly factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of IWS1 mRNA

NCBI chr18:23,969,352...24,011,560
Ensembl chr18:23,969,733...24,010,415

G

jade family PHD finger 1

decreases expression

EXP

Methapyrilene results in decreased expression of JADE1 mRNA

NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:126,471,124...126,524,252

G

Janus kinase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of JAK3 exon

NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222

G

janus kinase and microtubule interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of JAKMIP1 intron

NCBI chr14:77,871,034...77,991,566
Ensembl chr14:77,871,034...77,991,525

G

janus kinase and microtubule interacting protein 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of JAKMIP3 intron

NCBI chr 1:203,182,764...203,310,714
Ensembl chr 1:203,241,125...203,310,713

G

junctional adhesion molecule 3

increases methylation

ISO

Methapyrilene results in increased methylation of JAM3 intron

NCBI chr 8:33,767,606...33,828,451
Ensembl chr 8:33,767,607...33,828,623

G

jumonji and AT-rich interaction domain containing 2

affects methylation

ISO

Methapyrilene affects the methylation of JARID2 intron

NCBI chr17:19,983,217...20,163,598
Ensembl chr17:19,983,217...20,161,970

G

Jun dimerization protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of JDP2 intron

NCBI chr 6:110,988,927...111,033,392
Ensembl chr 6:110,992,806...111,033,392

G

junctional cadherin complex regulator

increases methylation

ISO

Methapyrilene results in increased methylation of JHY exon; Methapyrilene results in increased methylation of JHY intron

NCBI chr 8:50,173,602...50,230,429
Ensembl chr 8:50,173,123...50,230,542

G

junctophilin 2

increases methylation

ISO

Methapyrilene results in increased methylation of JPH2 intron

NCBI chr 3:172,414,246...172,478,678
Ensembl chr 3:172,414,256...172,478,348

G

junctophilin 3

affects methylation

ISO

Methapyrilene affects the methylation of JPH3 intron

NCBI chr19:66,702,497...66,763,948
Ensembl chr19:66,702,680...66,763,937

G

Jupiter microtubule associated homolog 1

increases expression

EXP

Methapyrilene results in increased expression of JPT1 mRNA

NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469

G

Jupiter microtubule associated homolog 2

increases expression

EXP

Methapyrilene results in increased expression of JPT2 protein

NCBI chr10:14,467,652...14,487,769
Ensembl chr10:14,467,661...14,535,664

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

Methapyrilene results in increased expression of JUN mRNA

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

JunD proto-oncogene, AP-1 transcription factor subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of JUND promoter

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148

G

junction plakoglobin

increases methylation

ISO

Methapyrilene results in increased methylation of JUP exon

NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429

G

kalirin, RhoGEF kinase

increases methylation

ISO

Methapyrilene results in increased methylation of KALRN intron

NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329

G

KN motif and ankyrin repeat domains 1

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of KANK1 intron
Methapyrilene results in decreased methylation of KANK1 exon

NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:232,445,658...232,500,839

G

KN motif and ankyrin repeat domains 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of KANK4 intron

NCBI chr 5:118,516,994...118,581,024
Ensembl chr 5:118,517,971...118,581,002

G

lysine acetyltransferase 2B

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of KAT2B mRNA
Methapyrilene results in increased methylation of KAT2B intron

PMID:30157460 PMID:30467583

NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616

G

lysine acetyltransferase 6A

decreases expression

EXP

Methapyrilene results in decreased expression of KAT6A mRNA

NCBI chr16:75,787,411...75,868,584
Ensembl chr16:75,787,411...75,866,099

G

katanin catalytic subunit A1 like 2

decreases expression

ISO

Methapyrilene results in decreased expression of KATNAL2 mRNA

NCBI chr18:72,806,967...72,883,091
Ensembl chr18:72,806,900...72,883,256

G

kazrin, periplakin interacting protein

affects methylation

ISO

Methapyrilene affects the methylation of KAZN intron

NCBI chr 5:159,675,803...160,666,084
Ensembl chr 5:159,675,803...160,664,154

G

potassium voltage-gated channel subfamily A member 2

increases methylation

ISO

Methapyrilene results in increased methylation of KCNA2 exon

NCBI chr 2:197,392,746...197,406,606
Ensembl chr 2:197,392,698...197,407,519

G

potassium voltage-gated channel subfamily A regulatory beta subunit 1

affects methylation

ISO

Methapyrilene affects the methylation of KCNAB1 intron

NCBI chr 2:151,446,975...151,913,636
Ensembl chr 2:151,446,947...151,913,636

G

potassium voltage-gated channel subfamily A regulatory beta subunit 2

increases methylation

ISO

Methapyrilene results in increased methylation of KCNAB2 intron; Methapyrilene results in increased methylation of KCNAB2 promoter

NCBI chr 5:168,182,228...168,270,760
Ensembl chr 5:168,184,613...168,270,760

G

potassium voltage-gated channel subfamily C member 2

increases methylation

ISO

Methapyrilene results in increased methylation of KCNC2 intron

NCBI chr 7:49,586,274...49,770,212
Ensembl chr 7:49,586,136...49,770,212

G

potassium voltage-gated channel subfamily D member 3

increases methylation

ISO

Methapyrilene results in increased methylation of KCND3 intron

NCBI chr 2:195,626,316...195,843,690
Ensembl chr 2:195,626,316...195,843,690

G

potassium voltage-gated channel modifier subfamily G member 1

increases methylation

ISO

Methapyrilene results in increased methylation of KCNG1 intron

NCBI chr 3:177,379,593...177,412,986
Ensembl chr 3:177,392,031...177,411,507

G

potassium voltage-gated channel subfamily H member 2

increases methylation

ISO

Methapyrilene results in increased methylation of KCNH2 intron

NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421

G

potassium voltage-gated channel subfamily H member 4

increases methylation

ISO

Methapyrilene results in increased methylation of KCNH4 intron

NCBI chr10:86,168,644...86,188,476
Ensembl chr10:86,168,644...86,188,476

G

potassium voltage-gated channel subfamily H member 8

increases methylation

ISO

Methapyrilene results in increased methylation of KCNH8 intron

NCBI chr 9:5,742,683...6,182,445
Ensembl chr 9:5,742,683...6,182,445

G

potassium voltage-gated channel interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of KCNIP1 intron

NCBI chr10:18,723,726...19,093,025
Ensembl chr10:18,723,726...19,093,087

G

potassium voltage-gated channel interacting protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of KCNIP3 intron

NCBI chr 3:135,130,331...135,196,031
Ensembl chr 3:135,132,119...135,196,216

G

potassium voltage-gated channel interacting protein 4

increases methylation

ISO

Methapyrilene results in increased methylation of KCNIP4 intron

NCBI chr14:65,593,297...66,743,994
Ensembl chr14:65,593,366...66,743,993

G

potassium inwardly-rectifying channel, subfamily J, member 12

increases methylation

ISO

Methapyrilene results in increased methylation of KCNJ12 polyA tail

NCBI chr10:46,196,110...46,245,008
Ensembl chr10:46,195,428...46,260,169

G

potassium two pore domain channel subfamily K member 2

affects methylation

ISO

Methapyrilene affects the methylation of KCNK2 intron

NCBI chr13:103,297,387...103,494,686
Ensembl chr13:103,297,393...103,494,686

G

potassium two pore domain channel subfamily K member 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of KCNK4 intron

NCBI chr 1:213,547,577...213,558,706
Ensembl chr 1:213,547,577...213,555,861

G

potassium calcium-activated channel subfamily M alpha 1

affects methylation
decreases expression
increases expression

ISO

Methapyrilene affects the methylation of KCNMA1 intron
Methapyrilene results in decreased expression of KCNMA1 mRNA
Methapyrilene results in increased expression of KCNMA1 mRNA

PMID:30157460 PMID:31555880 PMID:35690182

NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117

G

potassium calcium-activated channel subfamily N member 3

affects methylation

ISO

Methapyrilene affects the methylation of KCNN3 intron

NCBI chr 2:177,227,276...177,378,849
Ensembl chr 2:177,234,327...177,379,693

G

potassium voltage-gated channel subfamily Q member 1

affects methylation

ISO

Methapyrilene affects the methylation of KCNQ1 intron

NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:207,721,131...208,054,072

G

potassium voltage-gated channel subfamily Q member 3

increases methylation

ISO

Methapyrilene results in increased methylation of KCNQ3 intron

NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:99,619,544...99,914,610

G

potassium sodium-activated channel subfamily T member 1

increases methylation

ISO

Methapyrilene results in increased methylation of KCNT1 intron

NCBI chr 3:29,081,071...29,136,902
Ensembl chr 3:29,081,321...29,134,768

G

potassium channel tetramerization domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of KCTD1 intron

NCBI chr18:6,396,947...6,591,026
Ensembl chr18:6,396,947...6,515,191

G

potassium channel tetramerization domain containing 3

increases methylation

ISO

Methapyrilene results in increased methylation of KCTD3 intron

NCBI chr13:103,041,488...103,080,069
Ensembl chr13:103,041,490...103,080,009

G

potassium channel tetramerization domain containing 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of KCTD5 intron

NCBI chr10:13,583,781...13,609,762
Ensembl chr10:13,583,781...13,610,062

G

lysine demethylase 4A

affects methylation

ISO

Methapyrilene affects the methylation of KDM4A intron

NCBI chr 5:136,958,178...137,004,942
Ensembl chr 5:136,958,178...137,004,951

G

lysine demethylase 4B

increases methylation

ISO

Methapyrilene results in increased methylation of KDM4B intron

NCBI chr 9:1,245,885...1,324,384
Ensembl chr 9:1,245,899...1,324,384

G

lysine demethylase 5A

increases methylation

ISO

Methapyrilene results in increased methylation of KDM5A intron

NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:155,238,044...155,316,121

G

lysine demethylase 6B

decreases expression

EXP

Methapyrilene results in decreased expression of KDM6B mRNA

NCBI chr10:54,619,520...54,641,014
Ensembl chr10:54,619,544...54,629,610

G

lysine demethylase 7A

increases methylation

ISO

Methapyrilene results in increased methylation of KDM7A intron

NCBI chr 4:68,866,263...68,992,979
Ensembl chr 4:68,871,677...68,931,506

G

KH domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of KHDC1 intron

NCBI chr 9:31,309,032...31,311,266
Ensembl chr 9:31,296,805...31,311,422

G

KH-type splicing regulatory protein

increases methylation

ISO

Methapyrilene results in increased methylation of KHSRP intron

NCBI chr 9:1,949,557...1,959,400
Ensembl chr 9:1,949,557...1,959,497

G

KIAA0319 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of KIAA0319 exon

NCBI chr17:40,587,001...40,654,525
Ensembl chr17:40,590,546...40,653,679

G

KIAA0825 homolog

decreases methylation

ISO

Methapyrilene results in decreased methylation of KIAA0825 intron

NCBI chr 2:8,606,257...9,167,308
Ensembl chr 2:8,606,281...9,167,180

G

KIAA0930 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of KIAA0930 intron

NCBI chr 7:117,947,898...117,987,601
Ensembl chr 7:117,947,898...117,987,636

G

KIAA1671 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of KIAA1671 intron

NCBI chr12:49,069,929...49,212,604
Ensembl chr12:49,069,940...49,212,604

G

KIAA2012 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of KIAA2012 intron

NCBI chr 9:68,453,459...68,599,150
Ensembl chr 9:68,461,495...68,570,706

G

kinesin family member 11

increases expression

EXP

Methapyrilene results in increased expression of KIF11 mRNA

NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250

G

kinesin family member 16B

decreases expression

EXP

Methapyrilene results in decreased expression of KIF16B mRNA

NCBI chr 3:150,428,233...150,707,755
Ensembl chr 3:150,366,838...150,707,770

G

kinesin family member 19

increases methylation

ISO

Methapyrilene results in increased methylation of KIF19 exon; Methapyrilene results in increased methylation of KIF19 intron

NCBI chr10:100,298,912...100,325,591
Ensembl chr10:100,299,275...100,325,767

G

kinesin family member 1A

increases methylation

ISO

Methapyrilene results in increased methylation of KIF1A intron

NCBI chr 9:101,010,447...101,094,891
Ensembl chr 9:101,010,447...101,094,777

G

kinesin family member 26A

affects methylation

ISO

Methapyrilene affects the methylation of KIF26A intron

NCBI chr 6:137,035,986...137,072,027
Ensembl chr 6:137,033,789...137,072,022

G

kinesin family member 26B

affects methylation

ISO

Methapyrilene affects the methylation of KIF26B intron

NCBI chr13:92,815,427...93,221,071
Ensembl chr13:92,815,427...93,215,453

G

kinesin family member 4A

decreases methylation

ISO

Methapyrilene results in decreased methylation of KIF4A intron

NCBI chr X:69,761,803...69,864,335
Ensembl chr X:69,761,883...69,864,335

G

kinesin family member 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of KIF6 intron

NCBI chr 9:18,573,925...18,870,789
Ensembl chr 9:18,573,789...18,870,729

G

kinesin family member C1

increases expression

EXP

Methapyrilene results in increased expression of KIFC1 mRNA

NCBI chr20:5,000,929...5,018,967
Ensembl chr20:5,000,648...5,018,988

G

kirre like nephrin family adhesion molecule 3

increases methylation

ISO

Methapyrilene results in increased methylation of KIRREL3 intron

NCBI chr 8:41,123,692...41,663,528
Ensembl chr 8:41,123,878...41,664,147

G

KLF transcription factor 13

increases methylation

ISO

Methapyrilene results in increased methylation of KLF13 intron

NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:126,916,781...126,961,056

G

KLF transcription factor 15

decreases expression

EXP

Methapyrilene results in decreased expression of KLF15 mRNA

NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373

G

KLF transcription factor 16

increases methylation

ISO

Methapyrilene results in increased methylation of KLF16 intron

NCBI chr 7:9,789,185...9,799,004
Ensembl chr 7:9,775,042...9,798,999

G

kelch-like family member 2

decreases expression

EXP

Methapyrilene results in decreased expression of KLHL2 mRNA

NCBI chr16:29,627,171...29,739,782
Ensembl chr16:29,627,237...29,739,957

G

kelch-like family member 24

decreases expression

EXP

Methapyrilene results in decreased expression of KLHL24 mRNA

NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050

G

kelch-like family member 26

increases methylation

ISO

Methapyrilene results in increased methylation of KLHL26 intron

NCBI chr16:18,986,095...19,011,297
Ensembl chr16:18,985,865...19,011,297

G

kelch-like family member 29

increases methylation

ISO

Methapyrilene results in increased methylation of KLHL29 exon; Methapyrilene results in increased methylation of KLHL29 intron

NCBI chr 6:33,805,922...34,110,055
Ensembl chr 6:33,805,922...34,110,055

G

kelch-like family member 5

increases methylation

ISO

Methapyrilene results in increased methylation of KLHL5 polyA tail

NCBI chr14:43,497,915...43,565,833
Ensembl chr14:43,497,918...43,537,894

G

kelch-like family member 7

decreases expression

EXP

Methapyrilene results in decreased expression of KLHL7 mRNA

NCBI chr 4:11,898,766...11,947,796
Ensembl chr 4:11,898,769...11,947,796

G

kelch-like family member 9

decreases expression

EXP

Methapyrilene results in decreased expression of KLHL9 mRNA

NCBI chr 5:108,449,492...108,453,676
Ensembl chr 5:108,437,583...108,454,140

G

lysine methyltransferase 2A

increases methylation

ISO

Methapyrilene results in increased methylation of KMT2A exon

NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317

G

lysine methyltransferase 2B

increases methylation

ISO

Methapyrilene results in increased methylation of KMT2B exon

NCBI chr 1:94,949,144...94,969,239
Ensembl chr 1:94,949,144...94,968,441

G

kinase non-catalytic C-lobe domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of KNDC1 intron

NCBI chr 1:204,119,597...204,167,967
Ensembl chr 1:204,119,659...204,167,965

G

kinetochore-localized astrin/SPAG5 binding protein

increases expression

EXP

Methapyrilene results in increased expression of KNSTRN mRNA

NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:126,254,663...126,274,418

G

karyopherin subunit alpha 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of KPNA5 intron

NCBI chr20:31,365,647...31,430,793
Ensembl chr20:31,365,656...31,430,792

G

lysine-rich coiled-coil 1

decreases expression

EXP

Methapyrilene results in decreased expression of KRCC1 mRNA

NCBI chr 4:104,819,958...104,832,987
Ensembl chr 4:104,819,190...104,855,484

G

KRIT1, ankyrin repeat containing

decreases expression

EXP

Methapyrilene results in decreased expression of KRIT1 mRNA

NCBI chr 4:31,253,918...31,288,066
Ensembl chr 4:31,253,918...31,288,073

G

keratin 18

increases expression
affects expression

EXP

Methapyrilene results in increased expression of KRT18 mRNA
Methapyrilene affects the expression of KRT18 protein

PMID:28935588 PMID:30467583

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848

G

keratin 23

increases methylation

ISO

Methapyrilene results in increased methylation of KRT23 exon

NCBI chr10:84,930,603...84,946,929
Ensembl chr10:84,930,603...84,946,929

G

keratin 33A

decreases methylation

ISO

Methapyrilene results in decreased methylation of KRT33A exon

NCBI chr10:85,442,988...85,447,947
Ensembl chr10:85,442,988...85,447,947

G

keratin 5

increases methylation

ISO

Methapyrilene results in increased methylation of KRT5 exon

NCBI chr 7:134,724,840...134,730,569
Ensembl chr 7:134,724,840...134,730,569

G

keratin 73

increases expression

EXP

Methapyrilene results in increased expression of KRT73 protein

NCBI chr 7:134,806,517...134,815,028
Ensembl chr 7:134,806,517...134,815,028

G

keratin 8

increases expression
affects expression

EXP

Methapyrilene results in increased expression of KRT8 mRNA
Methapyrilene affects the expression of KRT8 protein

PMID:28935588 PMID:30467583

NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403

G

kinase suppressor of ras 1

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of KSR1 5' UTR
Methapyrilene results in decreased methylation of KSR1 exon; Methapyrilene results in decreased methylation of KSR1 intron

NCBI chr10:64,459,786...64,596,083
Ensembl chr10:64,459,786...64,596,082

G

kinase suppressor of ras 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of KSR2 intron

NCBI chr12:44,462,579...44,848,555
Ensembl chr12:44,471,038...44,848,308

G

kinectin 1

decreases expression

EXP

Methapyrilene results in decreased expression of KTN1 mRNA

NCBI chr15:23,392,570...23,485,061
Ensembl chr15:23,394,315...23,482,263

G

kynureninase

decreases expression

EXP

Methapyrilene results in decreased expression of KYNU mRNA

NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014

G

L-2-hydroxyglutarate dehydrogenase

increases methylation

ISO

Methapyrilene results in increased methylation of L2HGDH intron

NCBI chr 6:93,900,427...93,941,534
Ensembl chr 6:93,900,427...93,941,534

G

L3MBTL histone methyl-lysine binding protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of L3MBTL2 intron

NCBI chr 7:115,066,427...115,087,625
Ensembl chr 7:115,066,486...115,087,598

G

L3MBTL histone methyl-lysine binding protein 4

increases methylation

ISO

Methapyrilene results in increased methylation of L3MBTL4 intron

NCBI chr 9:115,741,720...116,194,592
Ensembl chr 9:115,776,638...116,194,591

G

laminin subunit alpha 3

increases methylation
affects methylation

ISO

Methapyrilene results in increased methylation of LAMA3 intron
Methapyrilene affects the methylation of LAMA3 exon

NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449

G

laminin subunit gamma 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of LAMC3 exon

NCBI chr 3:35,562,989...35,624,460
Ensembl chr 3:35,562,713...35,624,460

G

LARGE xylosyl- and glucuronyltransferase 1

affects methylation

ISO

Methapyrilene affects the methylation of LARGE intron

NCBI chr19:11,609,004...12,057,174
Ensembl chr19:11,609,004...12,054,707

G

La ribonucleoprotein 1, translational regulator

decreases expression

EXP

Methapyrilene results in decreased expression of LARP1 mRNA

NCBI chr10:42,691,833...42,746,816
Ensembl chr10:42,691,600...42,746,816

G

La ribonucleoprotein 4B

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of LARP4B mRNA
Methapyrilene results in increased methylation of LARP4B intron

PMID:30157460 PMID:30467583

NCBI chr17:65,813,125...65,908,920
Ensembl chr17:65,830,022...65,908,676

G

leucyl-tRNA synthetase 1

decreases expression

EXP

Methapyrilene results in decreased expression of LARS1 mRNA

NCBI chr18:34,452,567...34,507,030
Ensembl chr18:34,452,561...34,506,938

G

LBH domain containing 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of LBHD2 polyA tail

NCBI chr 6:136,263,383...136,268,422
Ensembl chr 6:136,263,572...136,268,422

G

ligand dependent nuclear receptor corepressor

decreases methylation

ISO

Methapyrilene results in decreased methylation of LCOR intron

NCBI chr 1:250,247,965...250,354,985
Ensembl chr 1:250,247,934...250,354,985

G

ligand dependent nuclear receptor corepressor-like

increases methylation

ISO

Methapyrilene results in increased methylation of LCORL intron

NCBI chr14:69,482,919...69,620,269
Ensembl chr14:69,518,837...69,587,177

G

LIM domain binding 3

increases methylation

ISO

Methapyrilene results in increased methylation of LDB3 intron

NCBI chr16:9,862,161...9,926,338
Ensembl chr16:9,862,161...9,926,985

G

low density lipoprotein receptor class A domain containing 4

increases methylation

ISO

Methapyrilene results in increased methylation of LDLRAD4 intron

NCBI chr18:63,789,089...64,118,166
Ensembl chr18:63,790,440...64,113,064

G

lymphoid enhancer binding factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of LEF1 intron

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929

G

leukocyte receptor cluster member 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of LENG8 intron

NCBI chr 1:79,113,038...79,124,868
Ensembl chr 1:79,113,038...79,124,738

G

leptin

decreases expression

EXP

Methapyrilene results in decreased expression of LEP protein

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

leucine zipper and EF-hand containing transmembrane protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of LETM1 intron

NCBI chr14:81,167,268...81,206,776
Ensembl chr14:81,162,309...81,209,459

G

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

decreases methylation

ISO

Methapyrilene results in decreased methylation of LFNG intron

NCBI chr12:19,144,474...19,152,951
Ensembl chr12:19,124,662...19,152,918

G

galectin 3

increases expression

EXP

Methapyrilene results in increased expression of LGALS3 mRNA

NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737

G

galectin 9

decreases expression

EXP

Methapyrilene results in decreased expression of LGALS9 mRNA

NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070

G

galectin-like

decreases expression

EXP

Methapyrilene results in decreased expression of LGALSL mRNA

NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487

G

leucine-rich repeat LGI family, member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of LGI2 intron

NCBI chr14:62,628,746...62,656,231
Ensembl chr14:62,596,150...62,656,188

G

leucine-rich repeat-containing G protein-coupled receptor 6

increases methylation

ISO

Methapyrilene results in increased methylation of LGR6 intron

NCBI chr13:48,976,193...49,095,870
Ensembl chr13:48,976,193...49,095,857

G

LHFPL tetraspan subfamily member 3

increases methylation

ISO

Methapyrilene results in increased methylation of LHFPL3 intron

G

LHFPL tetraspan subfamily member 6

increases methylation

ISO

Methapyrilene results in increased methylation of LHFPL6 intron

NCBI chr 2:139,276,810...139,474,740
Ensembl chr 2:139,276,789...139,474,737

G

LHFPL tetraspan subfamily member 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of LHFPL7 intron

NCBI chr12:49,053,607...49,057,890
Ensembl chr12:49,053,740...49,057,890

G

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

increases methylation

ISO

Methapyrilene results in increased methylation of LHPP intron

NCBI chr 1:196,833,516...196,924,687
Ensembl chr 1:196,833,523...196,924,871

G

LIM homeobox 4

increases methylation

ISO

Methapyrilene results in increased methylation of LHX4 intron

NCBI chr13:70,423,768...70,477,337
Ensembl chr13:70,427,399...70,467,505

G

LIM homeobox 6

increases methylation

ISO

Methapyrilene results in increased methylation of LHX6 intron

NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559

G

leukocyte immunoglobulin like receptor A5

increases methylation

ISO

Methapyrilene results in increased methylation of LILRA5 polyA tail

NCBI chr 1:79,011,865...79,073,860
Ensembl chr 1:79,045,546...79,050,111

G

LIM domain and actin binding 1

increases methylation

ISO

Methapyrilene results in increased methylation of LIMA1 intron

NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:132,780,556...132,880,386

G

LIM zinc finger domain containing 2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of LIMS2 mRNA
Methapyrilene results in increased methylation of LIMS2 intron

PMID:30157460 PMID:30467583

NCBI chr18:23,828,164...23,866,363
Ensembl chr18:23,837,686...23,867,086

G

lin-28 homolog B

increases methylation

ISO

Methapyrilene results in increased methylation of LIN28B intron

NCBI chr20:50,447,700...50,547,135
Ensembl chr20:50,450,971...50,541,968

G

lin-52 DREAM MuvB core complex component

increases methylation

ISO

Methapyrilene results in increased methylation of LIN52 intron

NCBI chr 6:109,829,896...109,927,122
Ensembl chr 6:109,830,131...109,925,310

G

lin-7 homolog B, crumbs cell polarity complex component

increases expression

EXP

Methapyrilene results in increased expression of LIN7B protein

NCBI chr 1:104,983,368...104,986,795
Ensembl chr 1:104,982,771...104,986,078

G

leucine rich repeat and Ig domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of LINGO1 intron; Methapyrilene results in increased methylation of LINGO1 promoter

NCBI chr 8:65,907,275...66,089,485
Ensembl chr 8:65,897,844...66,091,740

G

leucine rich repeat and Ig domain containing 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of LINGO2 intron

NCBI chr 5:55,166,250...56,488,672
Ensembl chr 5:55,156,997...56,489,155

G

lipase C, hepatic type

increases expression

EXP

Methapyrilene results in increased expression of LIPC mRNA

NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285

G

lipase G, endothelial type

increases methylation

ISO

Methapyrilene results in increased methylation of LIPG 3' UTR

NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260

G

lectin, mannose-binding 2-like

increases methylation

ISO

Methapyrilene results in increased methylation of LMAN2L intron

NCBI chr 9:46,157,596...46,181,151
Ensembl chr 9:46,157,596...46,181,207

G

lipase maturation factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of LMF1 intron

NCBI chr10:15,094,432...15,188,665
Ensembl chr10:15,098,138...15,188,664

G

leishmanolysin like peptidase

increases methylation

ISO

Methapyrilene results in increased methylation of LMLN intron

NCBI chr11:81,161,330...81,230,972
Ensembl chr11:81,161,330...81,229,447

G

lamin A/C

decreases methylation

ISO

Methapyrilene results in decreased methylation of LMNA intron

NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072

G

LIM domain only 4

decreases expression

EXP

Methapyrilene results in decreased expression of LMO4 mRNA

NCBI chr 2:235,924,574...235,941,609
Ensembl chr 2:235,924,403...235,941,275

G

leiomodin 1

increases methylation

ISO

Methapyrilene results in increased methylation of LMOD1 intron

NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116

G

LIM homeobox transcription factor 1 beta

affects methylation

ISO

Methapyrilene affects the methylation of LMX1B intron

NCBI chr 3:37,257,025...37,338,675
Ensembl chr 3:37,259,855...37,338,557

G

mucin-12-like

increases methylation

ISO

Methapyrilene results in increased methylation of MUC12 promoter

NCBI chr12:25,127,100...25,137,925

G

lon peptidase 1, mitochondrial

decreases methylation

ISO

Methapyrilene results in decreased methylation of LONP1 intron

NCBI chr 9:1,534,581...1,546,908
Ensembl chr 9:1,534,584...1,547,427

G

lon peptidase 2, peroxisomal

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of LONP2 polyA tail
Methapyrilene results in decreased expression of LONP2 mRNA

PMID:30157460 PMID:30467583

NCBI chr19:36,580,736...36,672,242
Ensembl chr19:36,580,736...36,672,242

G

LON peptidase N-terminal domain and ring finger 2

increases methylation

ISO

Methapyrilene results in increased methylation of LONRF2 intron

NCBI chr 9:48,524,962...48,566,353
Ensembl chr 9:48,530,549...48,570,807

G

lysyl oxidase

decreases expression

EXP

Methapyrilene results in decreased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810

G

lysyl oxidase-like 2

increases methylation

ISO

Methapyrilene results in increased methylation of LOXL2 intron

NCBI chr15:51,091,547...51,182,843
Ensembl chr15:51,069,997...51,182,842

G

lysophosphatidic acid receptor 5

increases methylation

ISO

Methapyrilene results in increased methylation of LPAR5 polyA tail

NCBI chr 4:159,556,735...159,570,216
Ensembl chr 4:159,554,805...159,571,894

G

lysophosphatidylcholine acyltransferase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of LPCAT1 intron

NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:31,594,622...31,644,946

G

lipin 2

decreases expression

EXP

Methapyrilene results in decreased expression of LPIN2 mRNA

NCBI chr 9:118,529,988...118,604,796
Ensembl chr 9:118,529,943...118,604,796

G

lipoprotein lipase

increases expression

EXP

Methapyrilene results in increased expression of LPL mRNA

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107

G

LPS responsive beige-like anchor protein

increases methylation

ISO

Methapyrilene results in increased methylation of LRBA intron

NCBI chr 2:173,919,330...174,500,536
Ensembl chr 2:173,921,747...174,500,527

G

leucine-rich repeats and guanylate kinase domain containing

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRGUK intron

NCBI chr 4:63,614,431...63,737,463
Ensembl chr 4:63,614,461...63,763,564

G

leucine-rich repeats and immunoglobulin-like domains 1

increases methylation

ISO

Methapyrilene results in increased methylation of LRIG1 intron

NCBI chr 4:128,687,723...128,788,219
Ensembl chr 4:128,687,723...128,788,219

G

leucine rich melanocyte differentiation associated

increases methylation

ISO

Methapyrilene results in increased methylation of LRMDA intron

NCBI chr15:1,275,139...2,334,153
Ensembl chr15:1,274,199...2,334,089

G

LDL receptor related protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of LRP3 mRNA

NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057

G

LDL receptor related protein 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRP5 intron

NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822

G

LDL receptor related protein 6

decreases expression

EXP

Methapyrilene results in decreased expression of LRP6 mRNA

NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716

G

LDL receptor related protein 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRP8 intron

NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207

G

leucine-rich pentatricopeptide repeat containing

decreases expression

EXP

Methapyrilene results in decreased expression of LRPPRC mRNA

NCBI chr 6:15,612,638...15,695,113
Ensembl chr 6:15,612,655...15,695,116

G

leucine rich repeat containing 25

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRRC25 exon

NCBI chr16:18,840,867...18,847,722
Ensembl chr16:18,840,867...18,846,464

G

leucine rich repeat containing 3

increases methylation

ISO

Methapyrilene results in increased methylation of LRRC3 3' UTR

NCBI chr20:10,758,399...10,763,358
Ensembl chr20:10,758,357...10,762,022

G

leucine rich repeat containing 32

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRRC32 intron

NCBI chr 1:162,196,995...162,209,563
Ensembl chr 1:162,197,653...162,209,563

G

leucine rich repeat containing 42

increases methylation

ISO

Methapyrilene results in increased methylation of LRRC42 intron

NCBI chr 5:127,243,484...127,264,599
Ensembl chr 5:127,243,486...127,264,599

G

leucine rich repeat containing 4B

increases methylation

ISO

Methapyrilene results in increased methylation of LRRC4B intron

NCBI chr 1:104,058,558...104,092,831
Ensembl chr 1:104,072,128...104,093,298

G

leucine rich repeat containing 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRRC7 intron

NCBI chr 2:249,792,441...250,294,267
Ensembl chr 2:249,805,448...250,293,718

G

leucine rich repeat containing 74A

increases methylation

ISO

Methapyrilene results in increased methylation of C14ORF166B intron

NCBI chr 6:112,117,226...112,147,152
Ensembl chr 6:112,117,241...112,148,068

G

leucine rich repeat containing 8 VRAC subunit C

increases methylation

ISO

Methapyrilene results in increased methylation of LRRC8C intron

NCBI chr14:4,528,721...4,621,259
Ensembl chr14:4,531,823...4,620,049

G

leucine rich repeat containing 8 VRAC subunit D

increases methylation

ISO

Methapyrilene results in increased methylation of LRRC8D intron

NCBI chr14:4,335,114...4,411,549
Ensembl chr14:4,332,130...4,445,639

G

leucine rich repeat and coiled-coil centrosomal protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRRCC1 intron

NCBI chr 2:88,746,904...88,781,532
Ensembl chr 2:88,746,443...88,781,542

G

LRR binding FLII interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of LRRFIP1 intron

NCBI chr 9:99,039,590...99,167,805
Ensembl chr 9:99,039,614...99,167,779

G

leucine-rich repeat kinase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRRK1 intron

NCBI chr 1:129,254,815...129,390,217
Ensembl chr 1:129,254,515...129,389,941

G

leucine-rich repeat kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of LRRK2 intron

NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239

G

leucine rich repeat neuronal 3

increases methylation

ISO

Methapyrilene results in increased methylation of LRRN3 intron

NCBI chr 6:64,216,164...64,247,293
Ensembl chr 6:64,215,878...64,247,614

G

leucine rich repeat transmembrane neuronal 3

increases methylation

ISO

Methapyrilene results in increased methylation of LRRTM3 intron

NCBI chr20:24,514,304...24,688,322
Ensembl chr20:24,514,284...24,689,002

G

leucine-rich repeats and transmembrane domains 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of LRTM2 5' UTR

NCBI chr 4:154,158,165...154,180,389
Ensembl chr 4:154,158,168...154,167,641

G

limbic system-associated membrane protein

increases methylation

ISO

Methapyrilene results in increased methylation of LSAMP intron

NCBI chr11:72,053,285...74,223,019
Ensembl chr11:72,053,285...72,702,134

G

LSM10, U7 small nuclear RNA associated

decreases expression

EXP

Methapyrilene results in decreased expression of LSM10 mRNA

NCBI chr 5:143,649,817...143,660,391
Ensembl chr 5:143,615,360...143,663,986

G

LSM12 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of LSM12 intron

NCBI chr10:87,618,518...87,640,556
Ensembl chr10:87,618,518...87,640,556

G

LSM14A mRNA processing body assembly factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of LSM14A intron

NCBI chr 1:96,101,990...96,146,578
Ensembl chr 1:96,101,992...96,146,448

G

LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

increases expression

EXP

Methapyrilene results in increased expression of LSM3 mRNA

NCBI chr 4:125,578,185...125,584,429
Ensembl chr 4:125,578,185...125,584,429

G

leucine-rich single-pass membrane protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of LSMEM1 intron

NCBI chr 6:62,978,880...62,988,750
Ensembl chr 6:62,978,885...62,988,750

G

lymphocyte-specific protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of LSP1 promoter

NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:207,044,159...207,077,893

G

lanosterol synthase

decreases methylation

ISO

Methapyrilene results in decreased methylation of LSS intron

NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253

G

latent transforming growth factor beta binding protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of LTBP2 intron

NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298

G

listerin E3 ubiquitin protein ligase 1

decreases expression

EXP

Methapyrilene results in decreased expression of LTN1 mRNA

NCBI chr11:40,090,169...40,147,159
Ensembl chr11:40,090,169...40,147,303

G

LTO1 maturation factor of ABCE1

increases expression

EXP

Methapyrilene results in increased expression of LTO1 mRNA

NCBI chr 1:209,502,900...209,510,237
Ensembl chr 1:209,498,312...209,517,347

G

lymphocyte antigen 6 family member G6E

increases methylation

ISO

Methapyrilene results in increased methylation of LY6G6E intron

NCBI chr20:3,749,352...3,752,578
Ensembl chr20:3,749,656...3,751,392

G

lymphocyte antigen 86

decreases methylation

ISO

Methapyrilene results in decreased methylation of LY86 intron

NCBI chr17:27,621,313...27,705,336
Ensembl chr17:27,621,313...27,692,743

G

lymphocyte antigen 96

decreases methylation

ISO

Methapyrilene results in decreased methylation of LY96 intron

NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:7,365,557...7,395,816

G

Ly6/Plaur domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of LYPD2 intron

NCBI chr 7:108,506,545...108,508,582
Ensembl chr 7:108,506,545...108,508,582

G

Ly6/Plaur domain containing 5

increases methylation

ISO

Methapyrilene results in increased methylation of LYPD5 intron

NCBI chr 1:89,057,719...89,069,696
Ensembl chr 1:89,057,891...89,069,696

G

Ly6/Plaur domain containing 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of LYPD6 intron

NCBI chr 3:54,896,618...55,041,928
Ensembl chr 3:54,896,575...55,041,929

G

LYR motif containing 2

decreases expression

EXP

Methapyrilene results in decreased expression of LYRM2 mRNA

NCBI chr 5:51,994,540...51,996,818
Ensembl chr 5:51,994,543...51,997,979

G

lysozyme 2

increases expression

EXP

Methapyrilene results in increased expression of LYZ2 mRNA

NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011

G

mono-ADP ribosylhydrolase 1

affects methylation

ISO

Methapyrilene affects the methylation of MACROD1 intron

NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348

G

mitotic arrest deficient 1 like 1

affects methylation

ISO

Methapyrilene affects the methylation of MAD1L1 intron

NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567

G

mitotic arrest deficient 2 like 1

increases expression

EXP

Methapyrilene results in increased expression of MAD2L1 mRNA

NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222

G

MAGE family member D1

increases methylation

ISO

Methapyrilene results in increased methylation of MAGED1 intron

NCBI chr X:63,416,464...63,423,167
Ensembl chr X:63,416,466...63,423,112

G

MAGE family member H1

decreases expression

EXP

Methapyrilene results in decreased expression of MAGEH1 mRNA

NCBI chr X:21,725,709...21,726,965
Ensembl chr X:21,718,669...21,727,219

G

membrane associated guanylate kinase, WW and PDZ domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of MAGI1 mRNA

NCBI chr 4:127,762,590...128,368,228
Ensembl chr 4:127,762,590...128,367,833

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of MAGI2 intron

NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:15,278,518...16,762,199

G

membrane associated guanylate kinase, WW and PDZ domain containing 3

decreases expression

EXP

Methapyrilene results in decreased expression of MAGI3 mRNA

NCBI chr 2:194,206,587...194,405,468
Ensembl chr 2:194,206,934...194,405,157

G

mal, T-cell differentiation protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of MAL2 mRNA

NCBI chr 7:87,790,239...87,823,219
Ensembl chr 7:87,790,239...87,850,403

G

MAM and LDL receptor class A domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MALRD1 intron

NCBI chr17:83,327,372...84,039,558
Ensembl chr17:83,327,372...84,039,559

G

MAM domain containing 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAMDC4 intron

NCBI chr 3:28,780,523...28,789,139
Ensembl chr 3:28,780,523...28,789,139

G

mastermind-like transcriptional coactivator 3

affects methylation

ISO

Methapyrilene affects the methylation of MAML3 intron

NCBI chr 2:137,871,267...138,288,615
Ensembl chr 2:137,871,267...138,287,960

G

mannosidase, alpha, class 1A, member 1

decreases expression

EXP

Methapyrilene results in decreased expression of MAN1A1 mRNA

NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,745,165...33,928,584

G

mannosidase, alpha, class 1A, member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAN1A2 intron

NCBI chr 2:190,636,134...190,784,975
Ensembl chr 2:190,615,094...190,784,975

G

mannosidase, alpha, class 1C, member 1

increases methylation

ISO

Methapyrilene results in increased methylation of MAN1C1 intron

NCBI chr 5:152,057,839...152,197,737
Ensembl chr 5:152,057,967...152,197,138

G

mannosidase, alpha, class 2A, member 1

decreases expression

EXP

Methapyrilene results in decreased expression of MAN2A1 mRNA

NCBI chr 9:111,698,913...111,855,257
Ensembl chr 9:111,698,913...111,867,850

G

mannosidase, alpha, class 2A, member 2

increases methylation

ISO

Methapyrilene results in increased methylation of MAN2A2 exon

NCBI chr 1:143,712,157...143,736,624
Ensembl chr 1:143,716,072...143,736,562

G

mannosidase beta

increases methylation

ISO

Methapyrilene results in increased methylation of MANBA intron

NCBI chr 2:226,583,968...226,676,520
Ensembl chr 2:226,583,917...226,676,517

G

mannosidase, endo-alpha

decreases expression

EXP

Methapyrilene results in decreased expression of MANEA mRNA

NCBI chr 5:44,992,937...45,015,084
Ensembl chr 5:44,992,937...45,015,084

G

monoamine oxidase A

decreases expression

EXP

Methapyrilene results in decreased expression of MAOA mRNA

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631

G

monoamine oxidase B

decreases expression

EXP

Methapyrilene results in decreased expression of MAOB mRNA

PMID:16393664 PMID:30467583

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:8,490,344...8,594,375

G

mitogen activated protein kinase kinase 3

increases expression

EXP

Methapyrilene results in increased expression of MAP2K3 mRNA

NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004

G

mitogen-activated protein kinase kinase kinase 14

increases methylation

ISO

Methapyrilene results in increased methylation of MAP3K14 intron

NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,665,417...88,715,592

G

mitogen-activated protein kinase kinase kinase 15

increases methylation

ISO

Methapyrilene results in increased methylation of MAP3K15 intron

NCBI chr X:38,522,143...38,667,746
Ensembl chr X:38,521,183...38,667,676

G

mitogen-activated protein kinase kinase kinase 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAP3K20 intron

NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538

G

mitogen-activated protein kinase kinase kinase 6

increases expression

EXP

Methapyrilene results in increased expression of MAP3K6 mRNA

NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111

G

MAP3K7 C-terminal like

increases methylation

ISO

Methapyrilene results in increased methylation of MAP3K7CL intron

NCBI chr11:40,276,839...40,321,848
Ensembl chr11:40,277,688...40,321,847

G

mitogen activated protein kinase kinase kinase kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of MAP4K2 exon

NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:213,074,377...213,096,987

G

mitogen-activated protein kinase kinase kinase kinase 3

affects methylation
decreases expression

ISO
EXP

Methapyrilene affects the methylation of MAP4K3 intron
Methapyrilene results in decreased expression of MAP4K3 mRNA

PMID:30157460 PMID:30467583

NCBI chr 6:20,029,246...20,198,583
Ensembl chr 6:20,029,397...20,198,583

G

microtubule-associated protein 6

increases expression

EXP

Methapyrilene results in increased expression of MAP6 mRNA

NCBI chr 1:162,980,339...163,046,548
Ensembl chr 1:162,980,181...163,046,548

G

MAP6 domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAP6D1 intron

NCBI chr11:94,238,552...94,244,781
Ensembl chr11:94,238,542...94,246,901

G

microtubule-associated protein 7

decreases expression

EXP

Methapyrilene results in decreased expression of MAP7 mRNA

NCBI chr 1:16,730,000...16,857,173
Ensembl chr 1:16,730,075...16,857,170

G

mitogen activated protein kinase 14

decreases expression

EXP

Methapyrilene results in decreased expression of MAPK14 mRNA

PMID:16393664 PMID:30467583

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen-activated protein kinase 1 interacting protein 1-like

decreases expression

EXP

Methapyrilene results in decreased expression of MAPK1IP1L mRNA

NCBI chr15:23,024,757...23,051,189

G

mitogen activated protein kinase 3

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of MAPK3 protein
Methapyrilene results in increased methylation of MAPK3 intron

PMID:30157460 PMID:30467583

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 6

increases expression

EXP

Methapyrilene results in increased expression of MAPK6 mRNA

NCBI chr 8:85,027,141...85,050,236
Ensembl chr 8:85,027,144...85,050,236

G

MAPK associated protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAPKAP1 intron

NCBI chr 3:38,113,268...38,315,913
Ensembl chr 3:38,113,323...38,315,913

G

MAPK activated protein kinase 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAPKAPK5 intron

NCBI chr12:40,654,220...40,673,740
Ensembl chr12:40,654,423...40,677,170

G

mitogen activated protein kinase binding protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of MAPKBP1 intron

NCBI chr 3:127,401,612...127,452,152
Ensembl chr 3:127,401,612...127,449,983

G

membrane associated ring-CH-type finger 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MARCHF1 intron

NCBI chr16:28,022,159...28,880,872
Ensembl chr16:28,022,159...28,881,054

G

membrane associated ring-CH-type finger 10

increases methylation

ISO

Methapyrilene results in increased methylation of MARCHF10 exon

NCBI chr10:90,832,647...90,975,700
Ensembl chr10:90,832,648...90,922,722

G

membrane associated ring-CH-type finger 6

decreases expression

EXP

Methapyrilene results in decreased expression of MARCHF6 mRNA

NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:84,166,570...84,243,792

G

macrophage receptor with collagenous structure

increases methylation

ISO

Methapyrilene results in increased methylation of MARCO exon

NCBI chr13:34,169,011...34,210,340
Ensembl chr13:34,169,011...34,201,255

G

microtubule affinity regulating kinase 3

decreases expression

EXP

Methapyrilene results in decreased expression of MARK3 mRNA

NCBI chr 6:136,447,327...136,537,409
Ensembl chr 6:136,448,531...136,537,404

G

methionyl-tRNA synthetase 1

decreases expression

EXP

Methapyrilene results in decreased expression of MARS1 mRNA

NCBI chr 7:65,006,456...65,023,880
Ensembl chr 7:64,998,544...65,023,753

G

MBL associated serine protease 2

increases methylation

ISO

Methapyrilene results in increased methylation of MASP2 intron

NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705

G

microtubule associated serine/threonine kinase family member 4

increases methylation

ISO

Methapyrilene results in increased methylation of MAST4 intron

NCBI chr 2:35,627,190...36,219,090
Ensembl chr 2:35,627,190...36,218,832

G

methionine adenosyltransferase 1A

decreases expression

EXP

Methapyrilene results in decreased expression of MAT1A mRNA; Methapyrilene results in decreased expression of MAT1A protein

NCBI chr16:17,017,168...17,035,368
Ensembl chr16:17,016,030...17,035,367

G

microtubule associated tyrosine carboxypeptidase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MATCAP1 intron

NCBI chr19:50,067,978...50,076,715
Ensembl chr19:50,069,015...50,076,709

G

matrilin 2

increases methylation

ISO

Methapyrilene results in increased methylation of MATN2 intron

NCBI chr 7:67,380,140...67,529,767
Ensembl chr 7:67,380,168...67,530,153

G

matrilin 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of MATN3 intron

NCBI chr 6:37,467,729...37,487,776
Ensembl chr 6:37,467,729...37,487,776

G

MYC associated zinc finger protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of MAZ exon

NCBI chr 1:191,060,271...191,065,722
Ensembl chr 1:191,060,280...191,065,339

G

myoglobin

increases methylation

ISO

Methapyrilene results in increased methylation of MB intron

NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958

G

methyl-CpG binding domain protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of MBD3 polyA tail

NCBI chr 7:9,961,053...9,970,845
Ensembl chr 7:9,963,797...9,970,265

G

mannose binding lectin 2

decreases expression

EXP

Methapyrilene results in decreased expression of MBL2 mRNA

NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546

G

metallo-beta-lactamase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of MBLAC1 mRNA

NCBI chr12:22,185,142...22,186,404
Ensembl chr12:22,184,917...22,200,899

G

muscleblind-like splicing regulator 1

increases methylation

ISO

Methapyrilene results in increased methylation of MBNL1 exon

NCBI chr 2:146,789,570...146,964,136
Ensembl chr 2:146,789,596...146,964,134

G

muscleblind-like splicing regulator 2

decreases expression

EXP

Methapyrilene results in decreased expression of MBNL2 mRNA

NCBI chr15:103,792,134...103,949,827
Ensembl chr15:103,792,152...103,949,827

G

myelin basic protein

increases methylation

ISO

Methapyrilene results in increased methylation of MBP intron

NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174

G

MCC regulator of WNT signaling pathway

increases methylation

ISO

Methapyrilene results in increased methylation of MCC intron

NCBI chr18:37,042,350...37,517,114
Ensembl chr18:37,049,253...37,517,076

G

methylcrotonyl-CoA carboxylase subunit 1

decreases expression

EXP

Methapyrilene results in decreased expression of MCCC1 mRNA

NCBI chr 2:120,727,313...120,779,334
Ensembl chr 2:120,727,316...120,779,554

G

methylcrotonyl-CoA carboxylase subunit 2

decreases expression

EXP

Methapyrilene results in decreased expression of MCCC2 mRNA

NCBI chr 2:33,039,044...33,110,092
Ensembl chr 2:33,039,045...33,110,299

G

MCF.2 cell line derived transforming sequence-like

increases methylation

ISO

Methapyrilene results in increased methylation of MCF2L intron

NCBI chr16:83,209,277...83,355,683
Ensembl chr16:83,209,280...83,354,956

G

minichromosome maintenance complex component 6

increases expression

EXP

Methapyrilene results in increased expression of MCM6 mRNA

NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467

G

mucolipin TRP cation channel 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MCOLN2 intron

NCBI chr 2:237,714,100...237,762,979
Ensembl chr 2:237,714,084...237,762,978

G

mitochondrial calcium uniporter

increases methylation

ISO

Methapyrilene results in increased methylation of MCU intron

NCBI chr20:27,960,520...28,123,103
Ensembl chr20:27,961,327...28,123,103

G

MyoD family inhibitor

increases methylation

ISO

Methapyrilene results in increased methylation of MDFI intron

NCBI chr 9:20,654,359...20,672,768
Ensembl chr 9:20,654,417...20,672,767

G

MyoD family inhibitor domain containing

decreases expression

EXP

Methapyrilene results in decreased expression of MDFIC mRNA

NCBI chr 4:44,938,301...45,018,157
Ensembl chr 4:44,938,480...45,018,156

G

MDM2 proto-oncogene

decreases expression
increases phosphorylation
increases expression

EXP

Methapyrilene results in decreased expression of MDM2 mRNA
Methapyrilene results in increased phosphorylation of MDM2 protein
Methapyrilene results in increased expression of MDM2 mRNA

PMID:15890375 PMID:18619722 PMID:22584684 PMID:25242409 PMID:26558467 More...

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

midasin AAA ATPase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MDN1 exon; Methapyrilene results in decreased methylation of MDN1 intron

NCBI chr 5:51,851,785...51,982,688
Ensembl chr 5:51,851,809...51,982,688

G

malic enzyme 3

increases methylation

ISO

Methapyrilene results in increased methylation of ME3 intron

NCBI chr 1:152,946,595...153,148,026
Ensembl chr 1:152,946,628...153,148,026

G

MDS1 and EVI1 complex locus

increases methylation

ISO

Methapyrilene results in increased methylation of MECOM intron

NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038

G

methyl CpG binding protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of MECP2 intron

NCBI chr X:156,932,481...156,995,981
Ensembl chr X:156,941,234...156,943,560

G

mediator complex subunit 13

decreases methylation

ISO

Methapyrilene results in decreased methylation of MED13 intron

NCBI chr10:71,584,354...71,674,614
Ensembl chr10:71,584,354...71,673,901

G

mediator complex subunit 13L

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of MED13L mRNA
Methapyrilene results in decreased methylation of MED13L intron

PMID:30157460 PMID:30467583

NCBI chr12:43,468,556...43,665,819
Ensembl chr12:43,468,556...43,665,819

G

mediator complex subunit 21

increases expression

EXP

Methapyrilene results in increased expression of MED21 mRNA

NCBI chr 4:181,291,191...181,314,504
Ensembl chr 4:181,291,271...181,298,234

G

mediator complex subunit 27

increases methylation

ISO

Methapyrilene results in increased methylation of MED27 intron

NCBI chr 3:33,027,240...33,201,240
Ensembl chr 3:33,027,525...33,201,240

G

mediator complex subunit 4

increases expression

EXP

Methapyrilene results in increased expression of MED4 mRNA

NCBI chr15:55,106,079...55,116,354
Ensembl chr15:55,105,998...55,116,429

G

maternally expressed 3

increases methylation

ISO

Methapyrilene results in increased methylation of MEG3 intron

NCBI chr 6:134,274,056...134,306,249

G

multiple EGF-like-domains 11

increases methylation

ISO

Methapyrilene results in increased methylation of MEGF11 intron

NCBI chr 8:73,787,568...74,113,228
Ensembl chr 8:73,787,397...74,111,690

G

multiple EGF-like-domains 6

increases methylation

ISO

Methapyrilene results in increased methylation of MEGF6 intron

NCBI chr 5:170,020,699...170,121,557
Ensembl chr 5:170,020,778...170,121,554

G

multiple EGF-like-domains 8

increases methylation

ISO

Methapyrilene results in increased methylation of MEGF8 exon

NCBI chr 1:90,030,057...90,079,423
Ensembl chr 1:90,030,388...90,079,422

G

meiosis initiator

increases methylation

ISO

Methapyrilene results in increased methylation of MEIOSIN intron

NCBI chr 1:87,873,020...87,896,092
Ensembl chr 1:87,872,760...87,906,314

G

Meis homeobox 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of MEIS3 intron

NCBI chr 1:85,986,602...86,000,873
Ensembl chr 1:85,990,050...86,000,873

G

maternal embryonic leucine zipper kinase

decreases expression

EXP

Methapyrilene results in decreased expression of MELK mRNA

NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247

G

mesenchyme homeobox 1

increases methylation

ISO

Methapyrilene results in increased methylation of MEOX1 intron

NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976

G

methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit

decreases expression

EXP

Methapyrilene results in decreased expression of METTL14 mRNA

NCBI chr 2:214,215,165...214,231,412
Ensembl chr 2:214,215,165...214,231,412

G

methyltransferase 16, RNA N6-adenosine

increases methylation

ISO

Methapyrilene results in increased methylation of METTL16 3' UTR

NCBI chr10:60,139,317...60,185,438
Ensembl chr10:60,139,330...60,187,571

G

methyltransferase 21C, AARS1 lysine

increases methylation

ISO

Methapyrilene results in increased methylation of METTL21C exon

NCBI chr 9:53,625,473...53,637,220
Ensembl chr 9:53,626,093...53,637,204

G

methyltransferase 23, arginine

decreases expression

EXP

Methapyrilene results in decreased expression of METTL23 mRNA

NCBI chr10:102,546,102...102,550,782
Ensembl chr10:102,545,430...102,553,909

G

methyltransferase 8, tRNA N3-cytidine

increases methylation

ISO

Methapyrilene results in increased methylation of METTL8 intron

NCBI chr 3:76,140,465...76,271,367
Ensembl chr 3:76,144,178...76,271,400

G

microfibril associated protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of MFAP2 intron

NCBI chr 5:158,595,121...158,603,283
Ensembl chr 5:158,597,512...158,610,656

G

milk fat globule EGF and factor V/VIII domain containing

increases methylation

ISO

Methapyrilene results in increased methylation of MFGE8 intron

NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431

G

mitofusin 1

decreases expression

EXP

Methapyrilene results in decreased expression of MFN1 mRNA

NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190

G

mitofusin 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MFN2 intron

NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495

G

major facilitator superfamily domain containing 6

decreases expression

EXP

Methapyrilene results in decreased expression of MFSD6 mRNA

NCBI chr 9:56,265,152...56,350,449
Ensembl chr 9:56,265,237...56,350,446

G

MAX dimerization protein MGA

decreases expression

EXP

Methapyrilene results in decreased expression of MGA mRNA

NCBI chr 3:127,300,558...127,396,694
Ensembl chr 3:127,328,264...127,394,826

G

maltase-glucoamylase

increases methylation

ISO

Methapyrilene results in increased methylation of MGAM intron

NCBI chr 4:70,408,263...70,568,752
Ensembl chr 4:70,408,263...70,568,752

G

maltase-glucoamylase 2

increases methylation

ISO

Methapyrilene results in increased methylation of MGAM2 intron

NCBI chr 4:70,590,706...70,682,462
Ensembl chr 4:70,590,706...70,682,462

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

decreases methylation

ISO

Methapyrilene results in decreased methylation of MGAT4A intron

NCBI chr 9:47,169,229...47,282,577
Ensembl chr 9:47,169,232...47,282,574

G

monoglyceride lipase

decreases expression

EXP

Methapyrilene results in decreased expression of MGLL mRNA

NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440

G

O-6-methylguanine-DNA methyltransferase

increases expression
decreases methylation

EXP
ISO

Methapyrilene results in increased expression of MGMT mRNA
Methapyrilene results in decreased methylation of MGMT intron

PMID:15890375 PMID:21813463 PMID:30157460

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482

G

microsomal glutathione S-transferase 3

decreases expression

EXP

Methapyrilene results in decreased expression of MGST3 mRNA

PMID:16393664 PMID:30467583

NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575

G

microtubule associated monooxygenase, calponin and LIM domain containing 3

decreases expression

EXP

Methapyrilene results in decreased expression of MICAL3 mRNA

NCBI chr 4:155,824,941...156,025,003
Ensembl chr 4:155,824,946...156,005,238

G

mitochondrial calcium uptake 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MICU1 intron

NCBI chr20:28,211,774...28,357,928
Ensembl chr20:28,211,691...28,359,919

G

midline 1

decreases expression

EXP

Methapyrilene results in decreased expression of MID1 mRNA

NCBI chr X:27,678,248...28,053,049
Ensembl chr X:27,681,867...27,906,105

G

MIER family member 2

increases methylation

ISO

Methapyrilene results in increased methylation of MIER2 intron

NCBI chr 7:10,804,238...10,819,979
Ensembl chr 7:10,804,268...10,819,979

G

mitoguardin 1

increases methylation

ISO

Methapyrilene results in increased methylation of MIGA1 intron

NCBI chr 2:243,884,071...243,939,059
Ensembl chr 2:243,886,617...243,937,086

G

MINDY lysine 48 deubiquitinase 4

increases methylation

ISO

Methapyrilene results in increased methylation of MINDY4 intron; Methapyrilene results in increased methylation of MINDY4 polyA tail

NCBI chr 4:85,689,049...85,797,553
Ensembl chr 4:85,675,899...85,795,160

G

mitochondrial intermediate peptidase

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of MIPEP mRNA
Methapyrilene results in decreased methylation of MIPEP intron

PMID:16393664 PMID:30157460

NCBI chr15:39,102,301...39,227,915
Ensembl chr15:39,102,115...39,227,914

G

microRNA 100

affects expression

EXP

Methapyrilene affects the expression of MIR100 mRNA

NCBI chr 8:50,798,295...50,798,374
Ensembl chr 8:50,798,295...50,798,374

G

microRNA 10b

increases expression

EXP

Methapyrilene results in increased expression of MIR10B mRNA

NCBI chr 3:80,035,859...80,035,967
Ensembl chr 3:80,035,859...80,035,967

G

microRNA 122

increases expression
decreases expression

EXP
ISO

Methapyrilene results in increased expression of MIR122 mRNA
Methapyrilene results in decreased expression of MIR122 mRNA

PMID:22363424 PMID:28935588

NCBI chr18:61,028,817...61,028,901

G

microRNA 138-1

increases methylation

ISO

Methapyrilene results in increased methylation of MIR138-1 promoter

NCBI chr 8:131,178,434...131,178,532
Ensembl chr 8:131,178,434...131,178,532

G

microRNA 149

increases expression

EXP

Methapyrilene results in increased expression of MIR149 mRNA

NCBI chr 9:100,861,800...100,861,888
Ensembl chr 9:100,861,800...100,861,888

G

microRNA 150

affects expression

EXP

Methapyrilene affects the expression of MIR150 mRNA

NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:104,741,487...104,741,571

G

microRNA 181c

decreases expression

EXP

Methapyrilene results in decreased expression of MIR181C mRNA

NCBI chr19:40,888,291...40,888,396
Ensembl chr19:40,888,291...40,888,396

G

microRNA 192

affects expression
increases expression

EXP

Methapyrilene affects the expression of MIR192 mRNA
Methapyrilene results in increased expression of MIR192 mRNA

PMID:24863736 PMID:24880025

NCBI chr 1:212,994,209...212,994,318
Ensembl chr 1:212,994,209...212,994,318

G

microRNA 196b

increases expression

EXP

Methapyrilene results in increased expression of MIR196B mRNA

NCBI chr 4:82,661,101...82,661,185

G

microRNA 19a

affects expression

EXP

Methapyrilene affects the expression of MIR19A mRNA

NCBI chr15:98,588,131...98,588,212
Ensembl chr15:98,588,131...98,588,212

G

microRNA 200a

increases expression

EXP

Methapyrilene results in increased expression of MIR200A mRNA; Methapyrilene results in increased expression of MIR200A mRNA alternative form

PMID:22363424 PMID:22584684

NCBI chr 5:171,930,717...171,930,805

G

microRNA 200c

increases expression

EXP

Methapyrilene results in increased expression of MIR200C mRNA alternative form

NCBI chr 4:159,209,965...159,210,033

G

microRNA 21

increases expression

EXP

Methapyrilene results in increased expression of MIR21 mRNA

NCBI chr10:71,902,600...71,902,691

G

microRNA 210

increases expression

EXP

Methapyrilene results in increased expression of MIR210 mRNA

NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034

G

microRNA 214

affects expression

EXP

Methapyrilene affects the expression of MIR214 mRNA

NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752

G

microRNA 22

affects expression

EXP

Methapyrilene affects the expression of MIR22 mRNA

NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425

G

microRNA 222

affects expression

EXP

Methapyrilene affects the expression of MIR222 mRNA

NCBI chr X:6,022,621...6,022,723
Ensembl chr X:6,022,621...6,022,723

G

microRNA 223

affects expression

EXP

Methapyrilene affects the expression of MIR223 mRNA

NCBI chr X:65,151,383...65,151,492
Ensembl chr X:65,151,383...65,151,492

G

microRNA 27a

affects expression

EXP

Methapyrilene affects the expression of MIR27A mRNA

NCBI chr19:40,859,603...40,859,689

G

microRNA 27b

affects expression

EXP

Methapyrilene affects the expression of MIR27B mRNA

NCBI chr17:1,819,147...1,819,243

G

microRNA 28

affects expression

EXP

Methapyrilene affects the expression of MIR28 mRNA

NCBI chr11:89,480,252...89,480,337

G

microRNA 300

decreases methylation

ISO

Methapyrilene results in decreased methylation of MIR300 polyA tail

NCBI chr 6:134,559,918...134,559,996
Ensembl chr 6:134,559,910...134,559,999

G

microRNA 30a

decreases expression
affects expression

EXP

Methapyrilene results in decreased expression of MIR30A mRNA alternative form
Methapyrilene affects the expression of MIR30A mRNA

PMID:22363424 PMID:24863736

NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011

G

microRNA 30c-1

increases expression

EXP

Methapyrilene results in increased expression of MIR30C-1 mRNA alternative form

NCBI chr 5:139,634,455...139,634,543

G

microRNA 30e

affects expression

EXP

Methapyrilene affects the expression of MIR30E mRNA

NCBI chr 5:139,637,450...139,637,541
Ensembl chr 5:139,637,450...139,637,541

G

microRNA 31

affects expression

EXP

Methapyrilene affects the expression of MIR31 mRNA

NCBI chr 5:108,714,849...108,714,954

G

microRNA 322

affects expression

EXP

Methapyrilene affects the expression of MIR322 mRNA

NCBI chr X:137,726,147...137,726,241

G

microRNA 327

increases expression

EXP

Methapyrilene results in increased expression of MIR327 mRNA

NCBI chr20:13,161,077...13,161,170

G

microRNA 337

increases expression

EXP

Methapyrilene results in increased expression of MIR337 mRNA alternative form

NCBI chr 6:134,321,142...134,321,238
Ensembl chr 6:134,321,141...134,321,237

G

microRNA 34a

increases expression

EXP

Methapyrilene results in increased expression of MIR34A mRNA

PMID:22584684 PMID:24880025

NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053

G

microRNA 34c

increases expression
affects expression

EXP

Methapyrilene results in increased expression of MIR34C mRNA
Methapyrilene affects the expression of MIR34C mRNA

PMID:22363424 PMID:24863736

NCBI chr 8:60,306,091...60,306,167

G

microRNA 351

increases expression

EXP

Methapyrilene results in increased expression of MIR351 mRNA

NCBI chr X:137,725,116...137,725,196

G

microRNA 375

affects expression

EXP

Methapyrilene affects the expression of MIR375 mRNA

NCBI chr 9:83,906,582...83,906,656

G

microRNA 410

increases expression

EXP

Methapyrilene results in increased expression of MIR410 mRNA

NCBI chr 6:134,579,763...134,579,838
Ensembl chr 6:134,579,759...134,579,839

G

microRNA 503

increases expression

EXP

Methapyrilene results in increased expression of MIR503 mRNA

NCBI chr X:137,725,856...137,725,926

G

microRNA 674

affects expression

EXP

Methapyrilene affects the expression of MIR674 mRNA

NCBI chr 3:124,507,170...124,507,246
Ensembl chr 3:124,507,170...124,507,246

G

microRNA 877

affects expression

EXP

Methapyrilene affects the expression of MIR877 mRNA

NCBI chr20:2,816,284...2,816,368
Ensembl chr20:2,816,284...2,816,368

G

microRNA 879

increases expression

EXP

Methapyrilene results in increased expression of MIR879 mRNA alternative form

NCBI chr 4:25,679,414...25,679,489

G

Mir9-2 host gene

decreases methylation

ISO

Methapyrilene results in decreased methylation of MIR9-2HG promoter

NCBI chr 2:15,909,918...16,100,226
Ensembl chr 2:15,928,032...15,937,468

G

microRNA 93

affects expression

EXP

Methapyrilene affects the expression of MIR93 mRNA

NCBI chr12:22,156,844...22,156,930

G

microRNA 99a

decreases expression
affects expression

EXP

Methapyrilene results in decreased expression of MIR99A mRNA
Methapyrilene affects the expression of MIR99A mRNA

PMID:22584684 PMID:24863736

NCBI chr11:29,687,392...29,687,472
Ensembl chr11:29,687,392...29,687,472

G

microRNA 99b

affects expression
decreases methylation

EXP
ISO

Methapyrilene affects the expression of MIR99B mRNA
Methapyrilene results in decreased methylation of MIR99B promoter

PMID:24863736 PMID:30157460

NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:67,350,060...67,350,139

G

microRNA let-7b

affects expression

EXP

Methapyrilene affects the expression of MIRLET7B mRNA

NCBI chr 7:118,684,038...118,684,122
Ensembl chr 7:118,684,038...118,684,122

G

microRNA let-7c

increases expression

EXP

Methapyrilene results in increased expression of MIRLET7C-1 mRNA alternative form

NCBI chr11:29,688,112...29,688,205
Ensembl chr11:29,688,107...29,688,214

G

MIS12 kinetochore complex component

decreases expression

EXP

Methapyrilene results in decreased expression of MIS12 mRNA

NCBI chr10:56,238,317...56,246,491
Ensembl chr10:56,238,181...56,253,800

G

melanocyte inducing transcription factor

increases methylation

ISO

Methapyrilene results in increased methylation of MITF intron

NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790

G

marker of proliferation Ki-67

increases expression

EXP

Methapyrilene results in increased expression of MKI67 protein

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

muskelin 1

increases methylation

ISO

Methapyrilene results in increased methylation of MKLN1 intron

NCBI chr 4:60,939,239...61,095,214
Ensembl chr 4:60,937,817...61,095,210

G

MAPK interacting serine/threonine kinase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MKNK2 3' UTR

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529

G

makorin, ring finger protein, 2

increases methylation

ISO

Methapyrilene results in increased methylation of MKRN2 intron

NCBI chr 4:150,334,164...150,352,271
Ensembl chr 4:150,334,142...150,352,263

G

modulator of VRAC current 1

decreases expression

EXP

Methapyrilene results in decreased expression of MLC1 mRNA

NCBI chr 7:121,926,356...121,949,484
Ensembl chr 7:121,926,356...121,946,698

G

mutL homolog 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of MLH1 polyA tail

NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011

G

MLLT10, histone lysine methyltransferase DOT1L cofactor

decreases expression

EXP

Methapyrilene results in decreased expression of MLLT10 mRNA

NCBI chr17:85,729,964...85,857,791
Ensembl chr17:85,730,751...85,857,789

G

MLLT3, super elongation complex subunit

affects methylation

ISO

Methapyrilene affects the methylation of MLLT3 intron

NCBI chr 5:107,305,008...107,561,352
Ensembl chr 5:107,284,766...107,561,352

G

metabolism of cobalamin associated C

decreases expression

EXP

Methapyrilene results in decreased expression of MMACHC mRNA

NCBI chr 5:135,403,094...135,409,285
Ensembl chr 5:135,402,404...135,409,235

G

metabolism of cobalamin associated D

decreases expression

EXP

Methapyrilene results in decreased expression of MMADHC mRNA

NCBI chr 3:55,117,832...55,135,735
Ensembl chr 3:55,117,833...55,135,851

G

monocyte to macrophage differentiation-associated

increases expression

EXP

Methapyrilene results in increased expression of MMD mRNA

NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609

G

monocyte to macrophage differentiation-associated 2

increases methylation

ISO

Methapyrilene results in increased methylation of MMD2 intron

NCBI chr12:17,075,870...17,123,255
Ensembl chr12:17,076,260...17,123,904

G

membrane metallo-endopeptidase

increases methylation

ISO

Methapyrilene results in increased methylation of MME intron

NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463

G

membrane magnesium transporter 1

decreases expression

EXP

Methapyrilene results in decreased expression of MMGT1 mRNA

NCBI chr X:139,445,834...139,458,169
Ensembl chr X:139,445,834...139,458,169

G

matrix metallopeptidase 15

decreases expression

EXP

Methapyrilene results in decreased expression of MMP15 mRNA

NCBI chr19:9,669,506...9,691,000
Ensembl chr19:9,669,506...9,691,000

G

methylmalonyl-CoA mutase

decreases expression

EXP

Methapyrilene results in decreased expression of MMUT mRNA; Methapyrilene results in decreased expression of MMUT protein

NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342

G

MN1 proto-oncogene, transcriptional regulator

decreases methylation

ISO

Methapyrilene results in decreased methylation of MN1 intron

NCBI chr12:50,841,632...50,880,795
Ensembl chr12:50,841,632...50,880,795

G

MOB kinase activator 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MOB2 intron

NCBI chr 1:206,522,523...206,579,502
Ensembl chr 1:206,522,523...206,579,449

G

MORN repeat containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of MORN1 intron

NCBI chr 5:170,928,086...170,987,219
Ensembl chr 5:170,929,321...170,987,218

G

Mov10 RNA helicase

increases methylation

ISO

Methapyrilene results in increased methylation of MOV10 exon

NCBI chr 2:194,982,014...195,003,513
Ensembl chr 2:194,982,014...195,003,442

G

MPN domain containing

decreases methylation

ISO

Methapyrilene results in decreased methylation of MPND intron

NCBI chr 9:926,714...933,620
Ensembl chr 9:925,799...933,616

G

metallophosphoesterase domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of MPPED1 exon; Methapyrilene results in increased methylation of MPPED1 intron

NCBI chr 7:116,811,841...116,891,789
Ensembl chr 7:116,811,721...116,891,778

G

myosin phosphatase Rho interacting protein

increases methylation

ISO

Methapyrilene results in increased methylation of MPRIP intron

NCBI chr10:44,953,472...45,073,388
Ensembl chr10:44,953,500...45,073,388

G

myelin protein zero-like 1

increases expression

EXP

Methapyrilene results in increased expression of MPZL1 mRNA

NCBI chr13:80,385,454...80,422,315
Ensembl chr13:80,385,456...80,422,390

G

melanocortin 2 receptor accessory protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of MRAP2 intron

NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:96,988,079...97,024,579

G

mannose receptor, C type 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MRC2 intron

NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055

G

myoregulin

decreases methylation

ISO

Methapyrilene results in decreased methylation of MRLN intron

NCBI chr20:18,405,858...18,422,874
Ensembl chr20:18,405,858...18,420,878

G

mitochondrial rRNA methyltransferase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of MRM3 intron

NCBI chr10:61,594,155...61,623,659
Ensembl chr10:61,593,999...61,600,865

G

maestro heat-like repeat family member 5

increases methylation

ISO

Methapyrilene results in increased methylation of MROH5 intron

NCBI chr 7:107,551,767...107,626,899
Ensembl chr 7:107,551,693...107,619,063

G

maestro heat-like repeat family member 6

increases methylation

ISO

Methapyrilene results in increased methylation of MROH6 polyA tail

NCBI chr 7:109,448,738...109,456,034
Ensembl chr 7:109,449,268...109,455,087

G

maestro heat-like repeat family member 7

increases methylation

ISO

Methapyrilene results in increased methylation of MROH7 intron

NCBI chr 5:126,692,649...126,740,180
Ensembl chr 5:126,692,649...126,731,161

G

maestro heat-like repeat family member 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of MROH8 intron

NCBI chr 3:166,294,008...166,362,460
Ensembl chr 3:166,297,394...166,362,427

G

mitochondrial ribosomal protein L28

decreases methylation

ISO

Methapyrilene results in decreased methylation of MRPL28 promoter

NCBI chr10:15,653,006...15,656,062
Ensembl chr10:15,653,179...15,666,971

G

mitochondrial ribosomal protein L45

increases expression

EXP

Methapyrilene results in increased expression of MRPL45 mRNA

NCBI chr10:82,805,039...82,816,862
Ensembl chr10:82,804,874...82,816,139

G

mitochondrial ribosomal protein L51

decreases expression

EXP

Methapyrilene results in decreased expression of MRPL51 mRNA

NCBI chr 4:159,677,988...159,681,650
Ensembl chr 4:159,677,827...159,681,641

G

mitochondrial ribosomal protein S18B

increases expression

EXP

Methapyrilene results in increased expression of MRPS18B mRNA

NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065

G

myocardin related transcription factor A

affects methylation

ISO

Methapyrilene affects the methylation of MRTFA intron

NCBI chr 7:114,424,481...114,594,594
Ensembl chr 7:114,424,481...114,594,594

G

myocardin related transcription factor B

increases methylation

ISO

Methapyrilene results in increased methylation of MRTFB intron

NCBI chr10:1,623,887...1,789,658
Ensembl chr10:1,623,940...1,789,658

G

membrane spanning 4-domains A15

increases methylation

ISO

Methapyrilene results in increased methylation of MS4A15 intron

NCBI chr 1:217,053,199...217,066,693
Ensembl chr 1:217,053,199...217,066,997

G

mutS homolog 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of MSH4 intron

NCBI chr 2:245,445,118...245,504,493
Ensembl chr 2:245,452,240...245,503,358

G

methylsterol monooxygenase 1

increases expression

EXP

Methapyrilene results in increased expression of MSMO1 mRNA

NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445

G

moesin

increases expression
increases methylation
decreases expression

EXP
ISO

Methapyrilene results in increased expression of MSN mRNA
Methapyrilene results in increased methylation of MSN intron
Methapyrilene results in decreased expression of MSN protein

PMID:30157460 PMID:30467583

NCBI chr X:65,005,546...65,073,512
Ensembl chr X:65,005,458...65,075,129

G

methionine sulfoxide reductase A

affects methylation

ISO

Methapyrilene affects the methylation of MSRA intron

NCBI chr15:42,514,818...42,853,278
Ensembl chr15:42,527,045...42,853,279

G

macrophage stimulating 1 receptor

decreases methylation

ISO

Methapyrilene results in decreased methylation of MST1R exon

NCBI chr 8:117,471,928...117,491,059
Ensembl chr 8:117,475,968...117,490,515

G

msh homeobox 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MSX2 intron

NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945

G

mitochondrially encoded cytochrome c oxidase I

increases expression

EXP

Methapyrilene results in increased expression of COX1 mRNA

NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853

G

metallothionein 1A

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of MT1A mRNA
Methapyrilene results in decreased expression of MT1A mRNA

PMID:15120968 PMID:15890375 PMID:30467583

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 2

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of MT2A mRNA
Methapyrilene results in decreased expression of MT2A mRNA

PMID:15890375 PMID:30467583

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709

G

metallothionein 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of MT3 promoter

NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,854,677...10,856,080

G

metastasis associated 1 family, member 3

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of MTA3 mRNA
Methapyrilene results in increased methylation of MTA3 intron

PMID:30157460 PMID:30467583

NCBI chr 6:16,619,575...16,739,732
Ensembl chr 6:16,621,998...16,739,485

G

mitochondrial amidoxime reducing component 1

decreases expression

EXP

Methapyrilene results in decreased expression of MTARC1 mRNA

NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252

G

mitochondrial carrier 2

decreases expression

EXP

Methapyrilene results in decreased expression of MTCH2 mRNA

NCBI chr 3:97,286,388...97,306,028
Ensembl chr 3:97,285,894...97,307,327

G

microtubule crosslinking factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SOGA2 intron

NCBI chr 9:113,722,138...113,888,413
Ensembl chr 9:113,753,000...113,888,098

G

mitochondrial fission regulator 1

increases methylation

ISO

Methapyrilene results in increased methylation of MTFR1 intron

NCBI chr 2:103,594,458...103,629,697
Ensembl chr 2:103,594,497...103,629,690

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of MTHFD1L intron

NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:42,849,374...43,038,309

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

increases expression

EXP

Methapyrilene results in increased expression of MTHFD2L mRNA

NCBI chr14:17,374,139...17,455,508
Ensembl chr14:17,374,144...17,454,322

G

myotubularin related protein 4

decreases expression

EXP

Methapyrilene results in decreased expression of MTMR4 mRNA

NCBI chr10:72,890,665...72,913,598
Ensembl chr10:72,889,827...72,913,598

G

mechanistic target of rapamycin kinase

decreases expression

EXP

Methapyrilene results in decreased expression of MTOR mRNA

NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435

G

MTSS I-BAR domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of MTSS1 mRNA

NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303

G

microsomal triglyceride transfer protein

decreases expression

EXP

Methapyrilene results in decreased expression of MTTP mRNA

NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650

G

microtubule associated scaffold protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of MTUS1 mRNA

NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474

G

mucin 19, oligomeric

decreases methylation

ISO

Methapyrilene results in decreased methylation of MUC19 exon

NCBI chr 7:124,897,424...125,018,582
Ensembl chr 7:124,897,424...125,018,582

G

mucin 2, oligomeric mucus/gel-forming

increases methylation

ISO

Methapyrilene results in increased methylation of MUC2 intron

NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280

G

mucin 5B, oligomeric mucus/gel-forming

increases methylation

ISO

Methapyrilene results in increased methylation of MUC5B intron

NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:206,346,400...206,378,367

G

murinoglobulin 6

affects methylation

ISO

Methapyrilene affects the methylation of CPAMD8 intron

NCBI chr 4:157,004,905...157,085,187
Ensembl chr 4:157,004,905...157,085,250

G

matrix remodeling associated 7

increases methylation

ISO

Methapyrilene results in increased methylation of MXRA7 polyA tail

NCBI chr10:102,501,848...102,530,231
Ensembl chr10:102,489,604...102,530,231

G

myosin binding protein H-like

increases methylation

ISO

Methapyrilene results in increased methylation of MYBPHL exon

NCBI chr 2:198,692,857...198,706,953
Ensembl chr 2:198,693,101...198,705,738

G

MYC proto-oncogene, bHLH transcription factor

increases expression
affects expression

EXP

Methapyrilene results in increased expression of MYC mRNA
Methapyrilene affects the expression of MYC mRNA

PMID:15890375 PMID:28903497

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

MYC binding protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of MYCBP2 mRNA

NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325

G

MYCN proto-oncogene, bHLH transcription factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYCN intron

NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508

G

MYD88, innate immune signal transduction adaptor

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYD88 promoter

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230

G

myosin heavy chain 11

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYH11 3' UTR

NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678

G

myosin heavy chain 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYH7 exon

NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194

G

myosin light chain 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYL2 intron

NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149

G

myosin light chain 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYL9 polyA tail

NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410

G

myosin light chain kinase

decreases expression

EXP

Methapyrilene results in decreased expression of MYLK mRNA

NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659

G

myosin light chain kinase 3

increases methylation

ISO

Methapyrilene results in increased methylation of MYLK3 intron

NCBI chr19:37,858,298...37,916,805
Ensembl chr19:37,865,141...37,915,827

G

myosin light chain kinase family, member 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYLK4 intron

NCBI chr17:31,877,739...31,956,012
Ensembl chr17:31,896,304...31,947,174

G

myosin XVI

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYO16 intron

NCBI chr16:85,586,428...86,066,537
Ensembl chr16:85,586,429...85,973,879

G

myosin XVIIIa

increases methylation

ISO

Methapyrilene results in increased methylation of MYO18A intron

NCBI chr10:63,152,303...63,253,543
Ensembl chr10:63,152,103...63,253,543

G

myosin Ib

decreases expression

EXP

Methapyrilene results in decreased expression of MYO1B mRNA

NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328

G

myosin 1C

increases methylation

ISO

Methapyrilene results in increased methylation of MYO1C intron

NCBI chr10:60,996,642...61,019,022
Ensembl chr10:60,996,638...61,019,022

G

myosin IG

increases methylation

ISO

Methapyrilene results in increased methylation of MYO1G exon

NCBI chr14:85,600,619...85,615,760
Ensembl chr14:85,600,619...85,615,760

G

myosin IIIA

increases methylation

ISO

Methapyrilene results in increased methylation of MYO3A intron

NCBI chr17:89,451,567...89,667,654
Ensembl chr17:89,451,567...89,667,654

G

myosin VC

increases methylation

ISO

Methapyrilene results in increased methylation of MYO5C exon

NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996

G

myosin VIIb

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of MYO7B exon
Methapyrilene results in decreased methylation of MYO7B intron

NCBI chr18:23,862,533...23,944,081
Ensembl chr18:23,862,533...23,944,049

G

myosin IXA

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYO9A intron

NCBI chr 8:69,044,853...69,248,094
Ensembl chr 8:69,044,885...69,245,231

G

myosin IXb

increases methylation

ISO

Methapyrilene results in increased methylation of MYO9B intron

NCBI chr16:17,979,374...18,064,100
Ensembl chr16:17,979,439...18,064,332

G

myomesin 2

affects methylation

ISO

Methapyrilene affects the methylation of MYOM2 intron

NCBI chr16:81,222,467...81,295,025
Ensembl chr16:81,221,938...81,295,162

G

myelin regulatory factor

increases methylation

ISO

Methapyrilene results in increased methylation of MYRF intron

NCBI chr 1:216,279,057...216,311,155
Ensembl chr 1:216,279,057...216,311,178

G

myelin regulatory factor-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of MYRFL intron

NCBI chr 7:54,289,430...54,406,097
Ensembl chr 7:54,289,332...54,405,868

G

myosin VIIA and Rab interacting protein

decreases expression

ISO

Methapyrilene results in decreased expression of MYRIP mRNA

NCBI chr 8:128,895,371...129,062,420
Ensembl chr 8:128,895,371...129,062,420

G

myelin transcription factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of MYT1 intron

NCBI chr 3:189,263,569...189,327,844
Ensembl chr 3:189,263,467...189,327,844

G

NEDD4 binding protein 2-like 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of N4BP2L2 intron

NCBI chr12:4,972,967...5,038,027
Ensembl chr12:4,972,990...5,033,405

G

N(alpha)-acetyltransferase 30, NatC catalytic subunit

decreases expression

EXP

Methapyrilene results in decreased expression of NAA30 mRNA

NCBI chr15:24,935,060...24,954,435
Ensembl chr15:24,935,260...24,954,437

G

NACC family member 2

decreases expression

EXP

Methapyrilene results in decreased expression of NACC2 mRNA

NCBI chr 3:29,278,077...29,345,098
Ensembl chr 3:29,281,190...29,344,840

G

NAD kinase

decreases expression

EXP

Methapyrilene results in decreased expression of NADK mRNA

NCBI chr 5:171,427,973...171,458,586
Ensembl chr 5:171,428,000...171,458,579

G

NAD kinase 2, mitochondrial

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of NADK2 protein
Methapyrilene results in decreased expression of NADK2 mRNA

NCBI chr 2:59,844,854...59,886,989
Ensembl chr 2:59,844,854...59,886,988

G

NAD synthetase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NADSYN1 intron

NCBI chr 1:208,410,914...208,439,242
Ensembl chr 1:208,410,914...208,439,207

G

N-acetylglutamate synthase

decreases expression

EXP

Methapyrilene results in decreased expression of NAGS mRNA

NCBI chr10:87,598,516...87,602,650
Ensembl chr10:87,598,220...87,602,650

G

NALCN channel auxiliary factor 1

affects methylation

ISO

Methapyrilene affects the methylation of NALF1 intron

NCBI chr16:86,415,540...86,938,150
Ensembl chr16:86,415,488...86,938,150

G

NALCN channel auxiliary factor 2

increases methylation

ISO

Methapyrilene results in increased methylation of NALF2 exon

NCBI chr X:68,965,327...68,991,201
Ensembl chr X:68,965,327...68,991,201

G

N-acetylneuraminic acid phosphatase

increases methylation

ISO

Methapyrilene results in increased methylation of NANP intron

NCBI chr 3:160,289,269...160,302,001
Ensembl chr 3:160,288,830...160,302,002

G

nucleosome assembly protein 1-like 1

increases expression

EXP

Methapyrilene results in increased expression of NAP1L1 mRNA

NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104

G

nucleosome assembly protein 1-like 3

decreases expression

EXP

Methapyrilene results in decreased expression of NAP1L3 mRNA

NCBI chr X:92,607,628...92,610,426
Ensembl chr X:92,604,626...92,610,687

G

nucleosome assembly protein 1-like 4

increases methylation

ISO

Methapyrilene results in increased methylation of NAP1L4 3' UTR

NCBI chr 1:208,139,105...208,175,597
Ensembl chr 1:208,139,113...208,174,569

G

NSF attachment protein gamma

decreases expression

EXP

Methapyrilene results in decreased expression of NAPG mRNA

NCBI chr18:58,710,702...58,729,450
Ensembl chr18:58,708,655...58,729,450

G

nicotinate phosphoribosyltransferase

decreases methylation

ISO

Methapyrilene results in decreased methylation of NAPRT polyA tail

NCBI chr 7:109,457,328...109,460,817
Ensembl chr 7:109,457,378...109,460,817

G

nuclear prelamin A recognition factor

increases methylation

ISO

Methapyrilene results in increased methylation of NARF intron

NCBI chr10:107,017,344...107,035,777
Ensembl chr10:107,016,510...107,037,283

G

N-acetyltransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of NAT1 mRNA

NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527

G

N-acetyltransferase domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of NATD1 3' UTR

NCBI chr10:46,079,650...46,089,829
Ensembl chr10:46,079,653...46,089,829

G

neuron navigator 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of NAV2 exon

NCBI chr 1:107,799,968...108,458,546
Ensembl chr 1:107,805,096...108,458,546

G

neuron navigator 3

increases methylation

ISO

Methapyrilene results in increased methylation of NAV3 intron

NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893

G

negative regulator of P-body association

decreases methylation

ISO

Methapyrilene results in decreased methylation of NBDY intron

NCBI chr X:20,964,915...20,965,121

G

neurobeachin-like 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of NBEAL2 intron

NCBI chr 8:119,481,608...119,511,997
Ensembl chr 8:119,481,608...119,514,384

G

NBR1, autophagy cargo receptor

decreases expression

EXP

Methapyrilene results in decreased expression of NBR1 mRNA

NCBI chr10:86,978,024...87,006,664
Ensembl chr10:86,977,885...87,007,012

G

neurocalcin delta

increases methylation

ISO

Methapyrilene results in increased methylation of NCALD intron

NCBI chr 7:70,417,683...70,849,763
Ensembl chr 7:70,419,433...70,849,482

G

neural cell adhesion molecule 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NCAM1 exon; Methapyrilene results in decreased methylation of NCAM1 intron

NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971

G

non-SMC condensin I complex, subunit D2

increases expression

EXP

Methapyrilene results in increased expression of NCAPD2 mRNA

NCBI chr 4:159,655,051...159,677,938
Ensembl chr 4:159,655,051...159,677,938

G

nuclear cap binding protein subunit 1

increases methylation

ISO

Methapyrilene results in increased methylation of NCBP1 intron

NCBI chr 5:65,211,632...65,244,532
Ensembl chr 5:65,211,358...65,244,665

G

nuclear cap binding subunit 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of NCBP3 intron

NCBI chr10:58,164,241...58,193,952
Ensembl chr10:58,164,234...58,193,964

G

neutrophil cytosolic factor 4

increases methylation

ISO

Methapyrilene results in increased methylation of NCF4 intron

NCBI chr 7:111,705,926...111,723,893
Ensembl chr 7:111,706,520...111,723,898

G

NCK adaptor protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of NCK2 intron

NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:53,231,381...53,332,394

G

NCK-associated protein 5

increases methylation

ISO

Methapyrilene results in increased methylation of NCKAP5 intron

NCBI chr13:39,922,576...40,835,849
Ensembl chr13:39,922,737...40,835,521

G

nuclear receptor coactivator 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NCOA1 intron

NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924

G

nuclear receptor coactivator 4

decreases expression

EXP

Methapyrilene results in decreased expression of NCOA4 mRNA

NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840

G

nuclear receptor co-repressor 1

decreases expression

EXP

Methapyrilene results in decreased expression of NCOR1 mRNA

NCBI chr10:47,498,852...47,641,612
Ensembl chr10:47,498,852...47,640,350

G

nuclear receptor co-repressor 2

affects methylation

ISO

Methapyrilene affects the methylation of NCOR2 intron

NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612

G

neuronal calcium sensor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NCS1 3' UTR

NCBI chr 3:34,920,949...34,966,554
Ensembl chr 3:34,920,971...34,968,711

G

NDRG family member 2

decreases expression

EXP

Methapyrilene results in decreased expression of NDRG2 mRNA

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

NDRG family member 4

increases methylation

ISO

Methapyrilene results in increased methylation of NDRG4 promoter

NCBI chr19:9,357,470...9,393,465
Ensembl chr19:9,357,470...9,392,972

G

N-deacetylase and N-sulfotransferase 3

increases methylation

ISO

Methapyrilene results in increased methylation of NDST3 intron

NCBI chr 2:214,386,804...214,552,739
Ensembl chr 2:214,389,447...214,539,164

G

NADH:ubiquinone oxidoreductase subunit A1

increases methylation

ISO

Methapyrilene results in increased methylation of NDUFA1 polyA tail

NCBI chr X:121,289,904...121,293,555
Ensembl chr X:121,289,925...121,293,555

G

NADH:ubiquinone oxidoreductase subunit A10

increases methylation

ISO

Methapyrilene results in increased methylation of NDUFA10 intron

NCBI chr 9:100,454,498...100,490,023
Ensembl chr 9:100,437,379...100,489,264

G

NADH:ubiquinone oxidoreductase subunit A5

increases expression

EXP

Methapyrilene results in increased expression of NDUFA5 mRNA

NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235

G

NADH:ubiquinone oxidoreductase subunit A8

decreases methylation

ISO

Methapyrilene results in decreased methylation of NDUFA8 intron

NCBI chr 3:39,783,479...39,799,507
Ensembl chr 3:39,783,479...39,799,507

G

NADH:ubiquinone oxidoreductase complex assembly factor 3

decreases expression

EXP

Methapyrilene results in decreased expression of NDUFAF3 mRNA

NCBI chr 8:118,139,891...118,141,723
Ensembl chr 8:118,139,892...118,141,723

G

NADH:ubiquinone oxidoreductase subunit C2

decreases methylation

ISO

Methapyrilene results in decreased methylation of NDUFC2 intron

NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419

G

NADH:ubiquinone oxidoreductase core subunit S1

decreases expression

EXP

Methapyrilene results in decreased expression of NDUFS1 mRNA; Methapyrilene results in decreased expression of NDUFS1 protein

NCBI chr 9:72,040,286...72,073,605
Ensembl chr 9:72,040,090...72,073,605

G

NADH:ubiquinone oxidoreductase core subunit V1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NDUFV1 exon

NCBI chr 1:210,729,856...210,735,103
Ensembl chr 1:210,729,858...210,734,949

G

nectin cell adhesion molecule 1

increases methylation

ISO

Methapyrilene results in increased methylation of PVRL1 intron

NCBI chr 8:52,998,662...53,061,745
Ensembl chr 8:52,998,662...53,086,664

G

NEDD4 E3 ubiquitin protein ligase

decreases expression

EXP

Methapyrilene results in decreased expression of NEDD4 mRNA

NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:82,264,649...82,349,633

G

NEDD4 like E3 ubiquitin protein ligase

decreases methylation

ISO

Methapyrilene results in decreased methylation of NEDD4L intron

NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824

G

neural precursor cell expressed, developmentally down-regulated 9

increases methylation

ISO

Methapyrilene results in increased methylation of NEDD9 intron

NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,495,492...23,675,668

G

neuronal growth regulator 1

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of NEGR1 intron
Methapyrilene results in decreased methylation of NEGR1 intron

NCBI chr 2:248,283,164...249,015,538
Ensembl chr 2:248,283,353...249,018,410

G

NIMA-related kinase 5

increases methylation

ISO

Methapyrilene results in increased methylation of NEK5 polyA tail

NCBI chr16:76,597,857...76,641,113
Ensembl chr16:76,597,747...76,641,832

G

NIMA-related kinase 7

decreases expression

EXP

Methapyrilene results in decreased expression of NEK7 mRNA

NCBI chr13:52,573,730...52,700,869
Ensembl chr13:52,573,730...52,700,823

G

negative elongation factor complex member A

decreases methylation

ISO

Methapyrilene results in decreased methylation of NELFA intron

NCBI chr14:81,033,470...81,057,546
Ensembl chr14:81,033,514...81,058,719

G

neural EGFL like 2

increases methylation

ISO

Methapyrilene results in increased methylation of NELL2 intron

NCBI chr 7:128,222,333...128,542,127
Ensembl chr 7:128,078,103...128,651,917

G

neudesin neurotrophic factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of NENF intron

NCBI chr13:105,419,113...105,425,911
Ensembl chr13:105,419,113...105,426,091

G

neuroepithelial cell transforming 1

decreases expression

EXP

Methapyrilene results in decreased expression of NET1 mRNA

NCBI chr17:71,251,145...71,280,345
Ensembl chr17:71,251,149...71,289,270

G

neuropilin and tolloid like 1

increases methylation

ISO

Methapyrilene results in increased methylation of NETO1 intron

NCBI chr18:81,905,455...82,028,730
Ensembl chr18:81,910,355...82,024,505

G

neuralized E3 ubiquitin protein ligase 1B

increases methylation

ISO

Methapyrilene results in increased methylation of NEURL1B intron

NCBI chr10:17,258,317...17,289,362
Ensembl chr10:17,258,328...17,289,362

G

neuralized E3 ubiquitin protein ligase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of NEURL3 intron

NCBI chr 9:45,990,373...45,998,470
Ensembl chr 9:45,990,375...45,998,535

G

NFAT activating protein with ITAM motif 1

affects methylation

ISO

Methapyrilene affects the methylation of NFAM1 intron

NCBI chr 7:116,019,383...116,055,628
Ensembl chr 7:116,020,311...116,055,378

G

neurofascin

increases methylation

ISO

Methapyrilene results in increased methylation of NFASC intron

NCBI chr13:46,549,369...46,735,989
Ensembl chr13:46,549,369...46,736,139

G

nuclear factor of activated T-cells 1

increases methylation

ISO

Methapyrilene results in increased methylation of NFATC1 intron

NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990

G

nuclear factor of activated T-cells 2

increases methylation

ISO

Methapyrilene results in increased methylation of NFATC2 intron

NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380

G

nuclear factor I/A

decreases expression

EXP

Methapyrilene results in decreased expression of NFIA mRNA

NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395

G

nuclear factor I/B

decreases expression

EXP

Methapyrilene results in decreased expression of NFIB mRNA

PMID:16393664 PMID:30467583

NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945

G

nuclear factor I/C

decreases methylation

ISO

Methapyrilene results in decreased methylation of NFIC intron

NCBI chr 7:8,928,423...8,963,455
Ensembl chr 7:8,904,117...8,963,409

G

nuclear factor I X

affects methylation

ISO

Methapyrilene affects the methylation of NFIX intron

NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092

G

nuclear factor kappa B subunit 1

decreases expression

EXP

Methapyrilene results in decreased expression of NFKB1 mRNA

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

nuclear factor kappa B subunit 2

increases expression

EXP

Methapyrilene results in increased expression of NFKB2 mRNA

NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637

G

NFKB inhibitor beta

decreases methylation

ISO

Methapyrilene results in decreased methylation of NFKBIB intron

NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366

G

NFKB inhibitor zeta

decreases expression

EXP

Methapyrilene results in decreased expression of NFKBIZ mRNA

NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767

G

nuclear factor related to kappa B binding protein

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of NFRKB intron
Methapyrilene results in decreased expression of NFRKB mRNA

PMID:30157460 PMID:30467583

NCBI chr 8:38,089,574...38,121,506
Ensembl chr 8:38,089,999...38,121,501

G

NFU1 iron-sulfur cluster scaffold

decreases expression

EXP

Methapyrilene results in decreased expression of NFU1 mRNA

NCBI chr 4:121,016,316...121,036,925
Ensembl chr 4:121,016,393...121,037,493

G

nerve growth factor

increases expression

EXP

Methapyrilene results in increased expression of NGF mRNA

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834

G

N-glycanase 1

decreases expression

EXP

Methapyrilene results in decreased expression of NGLY1 mRNA

NCBI chr15:11,584,475...11,640,977
Ensembl chr15:11,584,475...11,635,328

G

NHERF family PDZ scaffold protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NHERF1 intron

NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579

G

NHL repeat containing 2

decreases expression

EXP

Methapyrilene results in decreased expression of NHLRC2 mRNA

NCBI chr 1:265,594,915...265,655,647
Ensembl chr 1:265,594,915...265,676,143

G

NHS actin remodeling regulator

increases methylation

ISO

Methapyrilene results in increased methylation of NHS intron

NCBI chr X:36,185,067...36,524,711
Ensembl chr X:36,438,178...36,524,708

G

NHS-like 2

increases methylation

ISO

Methapyrilene results in increased methylation of NHSL2 intron

NCBI chr X:71,009,940...71,249,427
Ensembl chr X:71,009,949...71,241,289

G

niban apoptosis regulator 1

increases methylation

ISO

Methapyrilene results in increased methylation of NIBAN1 intron

NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724

G

NIM1 serine/threonine protein kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of NIM1K intron

NCBI chr 2:53,403,467...53,451,248
Ensembl chr 2:53,403,473...53,419,656

G

ninjurin 1

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of NINJ1 mRNA
Methapyrilene results in increased methylation of NINJ1 intron

PMID:30157460 PMID:30467583

NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,659,200...15,668,063

G

ninein-like

increases methylation

ISO

Methapyrilene results in increased methylation of NINL intron

NCBI chr 3:160,208,757...160,275,077
Ensembl chr 3:160,196,883...160,275,108

G

nipsnap homolog 1

decreases expression

EXP

Methapyrilene results in decreased expression of NIPSNAP1 mRNA

NCBI chr14:83,957,714...83,981,579
Ensembl chr14:83,957,702...83,981,576

G

sodium/potassium transporting ATPase interacting 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of NKAIN2 intron

NCBI chr 1:26,488,381...27,696,134
Ensembl chr 1:26,488,223...27,696,113

G

Sodium/potassium transporting ATPase interacting 4

increases methylation

ISO

Methapyrilene results in increased methylation of NKAIN4 intron

NCBI chr 3:188,430,862...188,451,561
Ensembl chr 3:188,430,243...188,453,760

G

NKD inhibitor of WNT signaling pathway 1

increases methylation

ISO

Methapyrilene results in increased methylation of NKD1 intron

NCBI chr19:34,649,803...34,722,846

G

NFKB repressing factor

increases methylation

ISO

Methapyrilene results in increased methylation of NKRF polyA tail

NCBI chr X:120,992,038...121,010,251
Ensembl chr X:120,992,038...121,010,251

G

NK2 homeobox 2

increases methylation

ISO

Methapyrilene results in increased methylation of NKX2-2 promoter

NCBI chr 3:155,072,621...155,083,699
Ensembl chr 3:155,073,250...155,083,249

G

neuroligin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NLGN1 intron

NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:110,186,573...110,909,984

G

NLR family, CARD domain containing 4

increases methylation

ISO

Methapyrilene results in increased methylation of NLRC4 intron

NCBI chr 6:26,743,658...26,771,783
Ensembl chr 6:26,743,698...26,770,563

G

NLR family, pyrin domain containing 12

increases methylation

ISO

Methapyrilene results in increased methylation of NLRP12 intron

NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341

G

NLR family, pyrin domain containing 1A

increases methylation

ISO

Methapyrilene results in increased methylation of NLRP1 intron

NCBI chr10:56,277,134...56,332,229
Ensembl chr10:56,277,134...56,323,880

G

NLR family pyrin domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of NLRP2 intron

NCBI chr 1:78,557,956...78,597,160
Ensembl chr 1:78,557,956...78,597,160

G

NLR family, pyrin domain containing 3

increases methylation

ISO

Methapyrilene results in increased methylation of NLRP3 intron

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

NLR family, pyrin domain containing 9

increases methylation

ISO

Methapyrilene results in increased methylation of NLRP9 exon

NCBI chr 1:77,320,034...77,370,366
Ensembl chr 1:77,319,218...77,378,658

G

N-myc (and STAT) interactor

decreases expression

EXP

Methapyrilene results in decreased expression of NMI mRNA

NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:56,811,314...56,848,717

G

nicotinamide nucleotide adenylyltransferase 2

increases methylation

ISO

Methapyrilene results in increased methylation of NMNAT2 intron

NCBI chr13:67,655,794...67,831,609
Ensembl chr13:67,655,807...67,831,608

G

N-myristoyltransferase 1

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of NMT1 exon
Methapyrilene results in increased methylation of NMT1 intron

NCBI chr10:88,488,918...88,525,496
Ensembl chr10:88,488,990...88,522,729

G

nicotinamide nucleotide transhydrogenase

decreases expression

EXP

Methapyrilene results in decreased expression of NNT mRNA

NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310

G

NOC2-like nucleolar associated transcriptional repressor

increases methylation

ISO

Methapyrilene results in increased methylation of NOC2L intron

NCBI chr 5:172,102,369...172,114,168
Ensembl chr 5:172,101,223...172,114,162

G

nocturnin

increases expression

EXP

Methapyrilene results in increased expression of NOCT mRNA

NCBI chr 2:137,422,074...137,442,282
Ensembl chr 2:137,422,074...137,442,282

G

nucleotide-binding oligomerization domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of NOD2 intron

NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846

G

nucleolar protein 10

decreases methylation

ISO

Methapyrilene results in decreased methylation of NOL10 intron

NCBI chr 6:45,861,773...45,954,067
Ensembl chr 6:45,872,960...45,954,066

G

nucleolar protein 4-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of NOL4L intron

NCBI chr 3:162,345,059...162,467,849
Ensembl chr 3:162,348,211...162,468,048

G

nucleolar protein 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of NOL9 intron

NCBI chr 5:167,829,249...167,849,364
Ensembl chr 5:167,829,264...167,849,366

G

nitric oxide synthase 3

increases methylation

ISO

Methapyrilene results in increased methylation of NOS3 promoter

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664

G

notch receptor 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of NOTCH3 intron

NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,784,272...11,834,778

G

NADPH oxidase 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of NOX4 intron

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483

G

NPC intracellular cholesterol transporter 2

increases expression

EXP

Methapyrilene results in increased expression of NPC2 mRNA

NCBI chr 6:110,128,325...110,149,245
Ensembl chr 6:110,128,325...110,150,004

G

aminopeptidase puromycin sensitive

increases methylation

ISO

Methapyrilene results in increased methylation of NPEPPS intron

NCBI chr10:82,687,869...82,770,363
Ensembl chr10:82,687,871...82,770,363

G

nephrocystin 4

increases methylation

ISO

Methapyrilene results in increased methylation of NPHP4 exon

NCBI chr 5:168,270,522...168,356,393
Ensembl chr 5:168,271,073...168,358,242

G

NPHS1 adhesion molecule, nephrin

increases expression

EXP

Methapyrilene results in increased expression of NPHS1 mRNA

NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521

G

nucleophosmin 1

increases expression

EXP

Methapyrilene results in increased expression of NPM1 mRNA

NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr X:18,245,740...18,256,024

G

nucleophosmin/nucleoplasmin 2

increases methylation

ISO

Methapyrilene results in increased methylation of NPM2 intron

NCBI chr15:52,131,973...52,145,710
Ensembl chr15:52,132,058...52,139,027

G

NAD(P)H quinone dehydrogenase 1

increases expression

EXP

Methapyrilene results in increased expression of NQO1 mRNA

PMID:15890375 PMID:23274394 PMID:25242409 PMID:28935588 PMID:30467583

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

decreases expression

EXP

Methapyrilene results in decreased expression of NQO2 mRNA

NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662

G

nuclear receptor subfamily 1, group H, member 3

decreases expression

EXP

Methapyrilene results in decreased expression of NR1H3 mRNA

NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532

G

nuclear receptor subfamily 1, group H, member 4

decreases expression

EXP

Methapyrilene results in decreased expression of NR1H4 mRNA

PMID:17450226 PMID:30467583

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389

G

nuclear receptor subfamily 1, group I, member 2

decreases expression

EXP

Methapyrilene results in decreased expression of NR1I2 mRNA

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

G

nuclear receptor subfamily 1, group I, member 3

decreases expression

EXP
ISO

Methapyrilene results in decreased expression of NR1I3 mRNA

PMID:17450226 PMID:28935588

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370

G

nuclear receptor subfamily 2, group C, member 1

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of NR2C1 intron
Methapyrilene results in decreased expression of NR2C1 mRNA

PMID:30157460 PMID:30467583

NCBI chr 7:30,602,338...30,655,610
Ensembl chr 7:30,603,018...30,658,349

G

nuclear receptor subfamily 2, group E, member 3

increases methylation

ISO

Methapyrilene results in increased methylation of NR2E3 3' UTR

NCBI chr 8:69,261,343...69,269,081
Ensembl chr 8:69,261,343...69,269,081

G

nuclear receptor subfamily 2, group F, member 6

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of NR2F6 mRNA
Methapyrilene results in increased methylation of NR2F6 intron

PMID:16393664 PMID:30157460

NCBI chr16:18,080,003...18,087,449
Ensembl chr16:18,080,003...18,087,449

G

nuclear receptor subfamily 3, group C, member 1

decreases expression

EXP

Methapyrilene results in decreased expression of NR3C1 mRNA

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843

G

nuclear receptor subfamily 5, group A, member 1

increases methylation

ISO

Methapyrilene results in increased methylation of NR5A1 intron

NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046

G

nuclear receptor subfamily 5, group A, member 2

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of NR5A2 mRNA
Methapyrilene results in decreased methylation of NR5A2 intron

PMID:30157460 PMID:30467583

NCBI chr13:50,865,253...50,985,107
Ensembl chr13:50,867,920...50,984,938

G

nebulin-related anchoring protein

increases methylation

ISO

Methapyrilene results in increased methylation of NRAP exon

NCBI chr 1:265,355,324...265,433,229
Ensembl chr 1:265,355,327...265,432,950

G

nuclear receptor binding protein 2

increases expression

EXP

Methapyrilene results in increased expression of NRBP2 mRNA

NCBI chr 7:109,679,330...109,685,656
Ensembl chr 7:109,679,330...109,685,588

G

neuregulin 1

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of NRG1 mRNA
Methapyrilene results in increased methylation of NRG1 intron

PMID:15890375 PMID:30157460

NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849

G

nuclear receptor interacting protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of NRIP1 mRNA

NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353

G

neuropilin 2

increases methylation

ISO

Methapyrilene results in increased methylation of NRP2 intron; Methapyrilene results in increased methylation of NRP2 polyA tail

NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871

G

NSFL1 cofactor

increases expression

EXP

Methapyrilene results in increased expression of NSFL1C mRNA

NCBI chr 3:160,438,708...160,463,261
Ensembl chr 3:160,438,708...160,463,228

G

neuronal vesicle trafficking associated 1

increases methylation

ISO

Methapyrilene results in increased methylation of NSG1 intron

NCBI chr14:76,861,079...76,882,822
Ensembl chr14:76,860,746...76,883,390

G

NSE1 homolog, SMC5-SMC6 complex component

increases methylation

ISO

Methapyrilene results in increased methylation of NSMCE1 intron

NCBI chr 1:189,462,801...189,489,188
Ensembl chr 1:189,462,677...189,491,432

G

NOP2/Sun RNA methyltransferase 3

increases methylation

ISO

Methapyrilene results in increased methylation of NSUN3 intron

NCBI chr11:50,960,187...51,062,366
Ensembl chr11:50,960,192...51,045,220

G

5'-nucleotidase, cytosolic IA

decreases methylation

ISO

Methapyrilene results in decreased methylation of NT5C1A intron

NCBI chr 5:140,758,219...140,782,706
Ensembl chr 5:140,757,729...140,778,968

G

5'-nucleotidase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of NT5DC1 mRNA

NCBI chr20:39,660,707...39,763,647
Ensembl chr20:39,660,707...39,786,449

G

5' nucleotidase, ecto

decreases expression

EXP

Methapyrilene results in decreased expression of NT5E mRNA

NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645

G

N-terminal asparagine amidase

increases methylation

ISO

Methapyrilene results in increased methylation of NTAN1 intron

NCBI chr10:2,618,239...2,633,185
Ensembl chr10:2,618,235...2,633,810

G

neurotrophin 3

increases methylation

ISO

Methapyrilene results in increased methylation of NTF3 intron

NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349

G

nth-like DNA glycosylase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NTHL1 intron

NCBI chr10:14,160,334...14,166,502
Ensembl chr10:14,160,330...14,166,966

G

N-terminal Xaa-Pro-Lys N-methyltransferase 1

increases expression

EXP

Methapyrilene results in increased expression of NTMT1 mRNA

NCBI chr 3:34,490,972...34,508,316
Ensembl chr 3:34,484,388...34,508,417

G

netrin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of NTN1 intron

NCBI chr10:53,398,852...53,597,595
Ensembl chr10:53,398,852...53,584,060

G

netrin 5

increases methylation

ISO

Methapyrilene results in increased methylation of NTN5 intron

NCBI chr 1:105,293,408...105,302,163
Ensembl chr 1:105,293,434...105,302,163

G

netrin G2

affects methylation

ISO

Methapyrilene affects the methylation of NTNG2 intron

NCBI chr 3:32,889,856...32,949,032
Ensembl chr 3:32,890,575...32,943,821

G

nucleoside-triphosphatase, cancer-related

decreases expression

EXP

Methapyrilene results in decreased expression of NTPCR mRNA

NCBI chr19:70,598,816...70,612,580
Ensembl chr19:70,593,274...70,613,197

G

neurotrophic receptor tyrosine kinase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of NTRK2 promoter

NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628

G

neurotensin receptor 1

affects methylation

ISO

Methapyrilene affects the methylation of NTSR1 intron

NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:187,983,778...188,033,934

G

nuclear casein kinase and cyclin-dependent kinase substrate 1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of NUCKS1 intron
Methapyrilene results in decreased expression of NUCKS1 mRNA

PMID:30157460 PMID:30467583

NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101

G

nudix hydrolase 1

increases methylation

ISO

Methapyrilene results in increased methylation of NUDT1 exon

NCBI chr12:19,416,411...19,423,448
Ensembl chr12:19,416,411...19,424,158

G

nudix hydrolase 12

decreases expression

EXP

Methapyrilene results in decreased expression of NUDT12 mRNA

NCBI chr 9:106,188,930...106,202,340
Ensembl chr 9:106,189,661...106,202,340

G

nudix hydrolase 3

increases methylation

ISO

Methapyrilene results in increased methylation of NUDT3 intron

NCBI chr20:5,636,184...5,688,770
Ensembl chr20:5,636,184...5,688,754

G

nudix hydrolase 4

decreases expression

EXP

Methapyrilene results in decreased expression of NUDT4 mRNA

NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491

G

nudix hydrolase 6

decreases expression

EXP

Methapyrilene results in decreased expression of NUDT6 mRNA

NCBI chr 2:122,218,031...122,234,488
Ensembl chr 2:122,217,861...122,234,344

G

nuclear FMR1 interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of NUFIP1 intron

NCBI chr15:57,838,864...57,869,597
Ensembl chr15:57,837,608...57,869,594

G

nuclear FMR1 interacting protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of NUFIP2 intron

NCBI chr10:63,072,964...63,105,823
Ensembl chr10:63,073,397...63,105,823

G

nuclear GTPase, germinal center associated

increases methylation

ISO

Methapyrilene results in increased methylation of NUGGC intron

NCBI chr15:43,997,446...44,041,716
Ensembl chr15:43,997,438...44,041,643

G

nucleoporin 210

increases methylation

ISO

Methapyrilene results in increased methylation of NUP210 exon

NCBI chr 4:125,068,736...125,167,238
Ensembl chr 4:125,068,736...125,167,047

G

nucleoporin 210-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of NUP210L promoter

NCBI chr 2:177,843,647...177,962,975
Ensembl chr 2:177,845,633...177,962,969

G

nucleoporin 37

decreases expression

EXP

Methapyrilene results in decreased expression of NUP37 mRNA

NCBI chr 7:24,443,998...24,497,088
Ensembl chr 7:24,463,301...24,508,741

G

nucleoporin 50

increases expression

EXP

Methapyrilene results in increased expression of NUP50 mRNA

NCBI chr 7:117,927,882...117,945,155
Ensembl chr 7:117,925,716...117,946,959

G

nucleoporin 62

decreases methylation

ISO

Methapyrilene results in decreased methylation of NUP62 intron

NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710

G

nucleoporin 85

increases methylation

ISO

Methapyrilene results in increased methylation of NUP85 intron

NCBI chr10:101,305,241...101,323,980
Ensembl chr10:101,305,390...101,324,641

G

nucleoporin 98 and 96 precursor

increases methylation

ISO

Methapyrilene results in increased methylation of NUP98 intron

NCBI chr 1:165,906,405...166,003,366
Ensembl chr 1:165,906,405...166,003,366

G

nuclear protein 1, transcriptional regulator

increases expression

EXP

Methapyrilene results in increased expression of NUPR1 mRNA

NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901

G

NUS1 dehydrodolichyl diphosphate synthase subunit

decreases expression

EXP

Methapyrilene results in decreased expression of NUS1 mRNA

NCBI chr20:32,354,519...32,381,265
Ensembl chr20:32,354,439...32,381,264

G

nucleolar and spindle associated protein 1

increases expression

EXP

Methapyrilene results in increased expression of NUSAP1 mRNA

NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237

G

NACHT and WD repeat domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of NWD1 intron

NCBI chr16:17,204,731...17,278,184
Ensembl chr16:17,157,352...17,270,664

G

NACHT and WD repeat domain containing 2

increases methylation

EXP

Methapyrilene results in increased methylation of NWD2 gene

NCBI chr14:44,833,623...45,024,962
Ensembl chr14:44,834,856...45,024,047

G

nucleoredoxin

affects methylation

ISO

Methapyrilene affects the methylation of NXN intron

NCBI chr10:61,607,557...61,745,807
Ensembl chr10:61,607,568...61,745,807

G

nucleoredoxin-like 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of NXNL2 intron

NCBI chr17:14,182,849...14,187,595
Ensembl chr17:14,182,849...14,188,208

G

neurexophilin and PC-esterase domain family member 4

decreases expression

EXP

Methapyrilene results in decreased expression of NXPE4 mRNA

NCBI chr 8:57,399,199...57,640,629
Ensembl chr 8:57,631,895...57,644,186

G

neurexophilin 3

increases methylation

ISO

Methapyrilene results in increased methylation of NXPH3 exon

NCBI chr10:80,953,080...80,956,746
Ensembl chr10:80,952,227...80,956,668

G

NYN domain and retroviral integrase containing

decreases methylation

ISO

Methapyrilene results in decreased methylation of NYNRIN exon

NCBI chr15:33,302,778...33,325,120
Ensembl chr15:33,295,954...33,324,383

G

nyctalopin

increases methylation

ISO

Methapyrilene results in increased methylation of NYX polyA tail

NCBI chr X:11,953,680...11,974,716
Ensembl chr X:11,953,018...11,974,810

G

alpha-2u globulin PGCL4

decreases expression

EXP

Methapyrilene results in decreased expression of OBP3 mRNA

PMID:15120968 PMID:15890375

NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675

G

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

increases methylation
affects methylation

ISO

Methapyrilene results in increased methylation of OBSCN exon
Methapyrilene affects the methylation of OBSCN intron

NCBI chr10:44,273,686...44,419,275
Ensembl chr10:44,288,866...44,419,297

G

outer dynein arm docking complex subunit 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ODAD1 intron

NCBI chr 1:105,530,196...105,557,358
Ensembl chr 1:105,531,085...105,558,023

G

ornithine decarboxylase 1

increases expression

EXP

Methapyrilene results in increased expression of ODC1 mRNA

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146

G

outer dense fiber of sperm tails 2-like

decreases expression

EXP

Methapyrilene results in decreased expression of ODF2L mRNA

NCBI chr 2:236,696,158...236,733,090
Ensembl chr 2:236,696,389...236,733,086

G

2-oxoglutarate and iron-dependent oxygenase domain containing 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of OGFOD3 intron

NCBI chr10:106,950,640...106,978,422
Ensembl chr10:106,950,641...106,978,992

G

O-linked N-acetylglucosamine (GlcNAc) transferase

decreases expression

EXP

Methapyrilene results in decreased expression of OGT mRNA

NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123

G

Opa interacting protein 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of OIP5 intron

NCBI chr 3:127,047,559...127,057,043
Ensembl chr 3:127,047,559...127,057,043

G

olfactomedin 1

decreases expression

ISO

Methapyrilene results in decreased expression of OLFM1 mRNA

NCBI chr 3:31,918,512...31,956,261
Ensembl chr 3:31,918,573...31,956,260

G

olfactomedin 2

increases methylation

ISO

Methapyrilene results in increased methylation of OLFM2 intron

NCBI chr 8:27,480,703...27,558,416
Ensembl chr 8:27,480,711...27,558,460

G

olfactomedin-like 2B

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of OLFML2B exon
Methapyrilene results in increased methylation of OLFML2B intron

NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342

G

olfactory receptor 947

increases methylation

ISO

Methapyrilene results in increased methylation of OR6C65 promoter

NCBI chr 7:4,160,583...4,161,521
Ensembl chr 7:4,160,583...4,161,521

G

OPA1, mitochondrial dynamin like GTPase

decreases expression

EXP

Methapyrilene results in decreased expression of OPA1 mRNA

NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955

G

oligophrenin 1

increases methylation

ISO

Methapyrilene results in increased methylation of OPHN1 intron

NCBI chr X:67,639,956...68,018,217
Ensembl chr X:67,643,252...68,016,831

G

5-oxoprolinase (ATP-hydrolysing)

decreases expression

EXP

Methapyrilene results in decreased expression of OPLAH mRNA

NCBI chr 7:109,892,136...109,932,403
Ensembl chr 7:109,891,405...109,915,979

G

opiorphin prepropeptide

increases expression

EXP

Methapyrilene results in increased expression of PROL1 mRNA

NCBI chr14:19,986,575...20,001,589
Ensembl chr14:19,986,575...20,001,589

G

optineurin

decreases expression

EXP

Methapyrilene results in decreased expression of OPTN mRNA

NCBI chr17:78,118,847...78,169,543
Ensembl chr17:78,118,866...78,169,543

G

olfactory receptor family 8 subfamily B member 8

increases methylation

ISO

Methapyrilene results in increased methylation of OR8B8 promoter

NCBI chr 8:45,882,321...45,883,253
Ensembl chr 8:45,882,321...45,883,253

G

origin recognition complex, subunit 1

increases methylation

ISO

Methapyrilene results in increased methylation of ORC1 intron

NCBI chr 5:128,552,975...128,581,943
Ensembl chr 5:128,552,991...128,577,071

G

origin recognition complex, subunit 3

decreases expression

EXP

Methapyrilene results in decreased expression of ORC3 mRNA

NCBI chr 5:53,923,264...53,977,869
Ensembl chr 5:53,923,393...53,978,115

G

oxysterol binding protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of OSBP2 intron

NCBI chr14:82,808,693...82,970,386
Ensembl chr14:82,808,693...82,970,532

G

oxysterol binding protein-like 1A

increases methylation

ISO

Methapyrilene results in increased methylation of OSBPL1A intron

NCBI chr18:4,178,734...4,383,511
Ensembl chr18:4,179,631...4,369,421

G

organic solute carrier partner 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of OSCP1 intron

NCBI chr 5:143,618,186...143,649,765
Ensembl chr 5:143,615,360...143,663,986

G

oxidative stress induced growth inhibitor 1

increases methylation

ISO

Methapyrilene results in increased methylation of OSGIN1 intron

NCBI chr19:64,380,336...64,409,165
Ensembl chr19:64,401,173...64,409,162

G

oncostatin M receptor

increases expression

EXP
ISO

Methapyrilene results in increased expression of OSMR mRNA

NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561

G

odd-skipped related transcription factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of OSR1 promoter

NCBI chr 6:38,088,688...38,100,010
Ensembl chr 6:38,093,011...38,100,021

G

osteoclast stimulating factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of OSTF1 intron

NCBI chr 1:225,428,661...225,475,851
Ensembl chr 1:225,428,661...225,541,027

G

ornithine transcarbamylase

increases expression

EXP

Methapyrilene results in increased expression of OTC protein

NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555

G

otoancorin

increases methylation

ISO

Methapyrilene results in increased methylation of OTOA intron

NCBI chr 1:185,074,271...185,142,149
Ensembl chr 1:185,074,268...185,141,658

G

otoferlin

increases methylation

ISO

Methapyrilene results in increased methylation of OTOF exon; Methapyrilene results in increased methylation of OTOF intron

NCBI chr 6:31,647,869...31,744,476
Ensembl chr 6:31,647,914...31,744,476

G

otogelin-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of OTOGL exon

NCBI chr 7:44,952,633...45,097,869
Ensembl chr 7:44,953,399...45,110,055

G

otopetrin 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of OTOP2 intron

NCBI chr10:101,063,701...101,073,271
Ensembl chr10:101,063,701...101,073,271

G

OTU deubiquitinase, ubiquitin aldehyde binding 2

increases methylation

ISO

Methapyrilene results in increased methylation of OTUB2 intron

NCBI chr 6:128,309,863...128,328,444
Ensembl chr 6:128,299,693...128,328,433

G

OTU deubiquitinase 7A

increases methylation

ISO

Methapyrilene results in increased methylation of OTUD7A intron

NCBI chr 1:126,476,275...126,800,037
Ensembl chr 1:126,693,712...126,799,301

G

OTU deubiquitinase 7B

increases methylation

ISO

Methapyrilene results in increased methylation of OTUD7B 3' UTR

NCBI chr 2:186,350,811...186,411,461
Ensembl chr 2:186,350,798...186,409,440

G

oxidation resistance 1

increases methylation

ISO

Methapyrilene results in increased methylation of OXR1 intron

NCBI chr 7:74,413,609...74,850,487
Ensembl chr 7:74,413,590...74,850,487

G

oxidative stress responsive kinase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of OXSR1 intron

NCBI chr 8:127,850,481...127,941,518
Ensembl chr 8:127,850,484...127,939,750

G

purinergic receptor P2X 3

increases methylation

ISO

Methapyrilene results in increased methylation of P2RX3 exon

NCBI chr 3:90,487,506...90,531,315
Ensembl chr 3:90,487,506...90,531,794

G

purinergic receptor P2X 4

decreases expression

EXP

Methapyrilene results in decreased expression of P2RX4 mRNA

NCBI chr12:39,505,438...39,523,349
Ensembl chr12:39,505,438...39,523,094

G

pyrimidinergic receptor P2Y6

increases methylation

ISO

Methapyrilene results in increased methylation of P2RY6 intron

NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:164,706,116...164,743,588

G

prolyl 3-hydroxylase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of P3H3 intron

NCBI chr 4:159,332,514...159,348,428
Ensembl chr 4:159,332,434...159,348,004

G

prolyl 4-hydroxylase subunit alpha 1

increases methylation

ISO

Methapyrilene results in increased methylation of P4HA1 intron

NCBI chr20:27,784,696...27,895,785
Ensembl chr20:27,845,141...27,895,404

G

prolyl 4-hydroxylase subunit beta

increases expression

EXP

Methapyrilene results in increased expression of P4HB protein

NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911

G

PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

decreases expression

EXP

Methapyrilene results in decreased expression of PABIR1 mRNA

NCBI chr 1:231,541,411...231,542,717
Ensembl chr 1:231,537,357...231,612,411

G

parkin coregulated

increases methylation

ISO

Methapyrilene results in increased methylation of PACRG intron

NCBI chr 1:52,430,390...52,853,272
Ensembl chr 1:52,430,284...52,853,269

G

PAF1 homolog, Paf1/RNA polymerase II complex component

decreases methylation

ISO

Methapyrilene results in decreased methylation of PAF1 polyA tail

NCBI chr 1:92,811,197...92,816,775
Ensembl chr 1:92,798,237...92,816,779

G

platelet-activating factor acetylhydrolase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PAFAH2 3' UTR

NCBI chr 5:151,890,751...151,919,896
Ensembl chr 5:151,896,832...151,919,894

G

phenylalanine hydroxylase

decreases expression

EXP

Methapyrilene results in decreased expression of PAH mRNA

NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627

G

poly(A) binding protein interacting protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of PAIP1 mRNA

NCBI chr 2:53,255,916...53,282,965
Ensembl chr 2:53,237,924...53,282,966

G

p21 (RAC1) activated kinase 2

decreases expression

EXP

Methapyrilene results in decreased expression of PAK2 mRNA

NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803

G

p21 (RAC1) activated kinase 4

increases methylation

ISO

Methapyrilene results in increased methylation of PAK4 intron

NCBI chr 1:92,977,437...93,016,721
Ensembl chr 1:92,977,437...93,016,721

G

p21 (RAC1) activated kinase 6

increases methylation

ISO

Methapyrilene results in increased methylation of PAK6 3' UTR

NCBI chr 3:126,092,576...126,128,320
Ensembl chr 3:126,093,013...126,128,318

G

paralemmin A kinase anchor protein

increases methylation

ISO

Methapyrilene results in increased methylation of PALM2AKAP2 intron

NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656

G

phosphatase domain containing, paladin 1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of PALD1 intron
Methapyrilene results in decreased expression of PALD1 mRNA

PMID:30157460 PMID:30467583

NCBI chr20:29,812,650...29,877,733
Ensembl chr20:29,812,650...29,850,063

G

paralemmin

increases methylation

ISO

Methapyrilene results in increased methylation of PALM intron

NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:10,537,277...10,563,007

G

protein associated with LIN7 2, MAGUK p55 family member

decreases expression

EXP

Methapyrilene results in decreased expression of PALS2 mRNA

NCBI chr 4:80,504,298...80,584,951
Ensembl chr 4:80,455,657...80,584,950

G

poly(A) specific ribonuclease subunit PAN3

increases methylation

ISO

Methapyrilene results in increased methylation of PAN3 intron

NCBI chr12:12,512,835...12,637,066
Ensembl chr12:12,512,835...12,631,492

G

pantothenate kinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PANK1 mRNA

NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824

G

polyamine oxidase

decreases expression

EXP

Methapyrilene results in decreased expression of PAOX mRNA

NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:204,348,987...204,358,481

G

papilin, proteoglycan-like sulfated glycoprotein

increases methylation

ISO

Methapyrilene results in increased methylation of PAPLN intron

NCBI chr 6:109,129,268...109,163,300
Ensembl chr 6:109,129,261...109,161,483

G

poly (A) polymerase alpha

decreases expression

EXP

Methapyrilene results in decreased expression of PAPOLA mRNA

NCBI chr 6:130,446,236...130,499,371
Ensembl chr 6:130,446,797...130,499,336

G

pappalysin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PAPPA intron

NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361

G

par-3 family cell polarity regulator beta

increases methylation

ISO

Methapyrilene results in increased methylation of PARD3B intron

NCBI chr 9:70,532,358...71,561,044
Ensembl chr 9:70,532,644...71,560,554

G

par-6 family cell polarity regulator beta

increases expression

EXP

Methapyrilene results in increased expression of PARD6B mRNA

NCBI chr 3:177,209,429...177,230,509
Ensembl chr 3:177,209,258...177,230,510

G

poly(A)-specific ribonuclease

decreases methylation

ISO

Methapyrilene results in decreased methylation of PARN intron

NCBI chr10:1,917,830...2,055,749
Ensembl chr10:1,917,830...2,055,722

G

poly (ADP-ribose) polymerase family, member 11

decreases methylation

ISO

Methapyrilene results in decreased methylation of PARP11 intron

NCBI chr 4:161,984,192...162,030,550
Ensembl chr 4:161,991,042...162,030,557

G

poly (ADP-ribose) polymerase family, member 14

increases methylation

ISO

Methapyrilene results in increased methylation of PARP14 intron

NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195

G

poly (ADP-ribose) polymerase family, member 9

decreases expression

EXP

Methapyrilene results in decreased expression of PARP9 mRNA

NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608

G

parvin, gamma

increases methylation

ISO

Methapyrilene results in increased methylation of PARVG intron

NCBI chr 7:117,336,160...117,366,341
Ensembl chr 7:117,336,187...117,362,155

G

PAS domain containing repressor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PASD1 intron

NCBI chr X:154,662,718...154,684,001
Ensembl chr X:154,662,727...154,683,998

G

PATJ, crumbs cell polarity complex component

decreases methylation

ISO

Methapyrilene results in decreased methylation of PATJ intron

NCBI chr 5:118,177,557...118,480,301
Ensembl chr 5:118,177,565...118,480,301

G

paired box 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PAX2 intron

NCBI chr 1:253,555,447...253,646,623
Ensembl chr 1:253,555,418...253,645,438

G

paired box 7

affects methylation

ISO

Methapyrilene affects the methylation of PAX7 intron

NCBI chr 5:157,279,623...157,381,188
Ensembl chr 5:157,279,623...157,381,121

G

phenazine biosynthesis-like protein domain containing 1

increases expression

EXP

Methapyrilene results in increased expression of PBLD1 protein

NCBI chr20:25,549,974...25,565,390
Ensembl chr20:25,549,974...25,565,226

G

polybromo 1

decreases expression

EXP

Methapyrilene results in decreased expression of PBRM1 mRNA

NCBI chr16:6,219,933...6,319,336
Ensembl chr16:6,219,917...6,319,336

G

PBX homeobox 3

increases expression

EXP

Methapyrilene results in increased expression of PBX3 mRNA

NCBI chr 3:37,886,241...38,079,956
Ensembl chr 3:37,886,687...38,079,895

G

pyruvate carboxylase

decreases expression
affects methylation

EXP
ISO

Methapyrilene results in decreased expression of PC mRNA
Methapyrilene affects the methylation of PC intron

PMID:16393664 PMID:30157460 PMID:30467583

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940

G

propionyl-CoA carboxylase subunit alpha

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of PCCA intron
Methapyrilene results in decreased expression of PCCA mRNA

PMID:30157460 PMID:30467583

NCBI chr15:106,034,586...106,374,908
Ensembl chr15:106,034,610...106,374,908

G

protocadherin related 15

decreases methylation

ISO

Methapyrilene results in decreased methylation of PCDH15 intron

NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958

G

protocadherin 9

increases methylation

ISO

Methapyrilene results in increased methylation of PCDH9 exon; Methapyrilene results in increased methylation of PCDH9 intron

NCBI chr15:75,748,472...76,646,644
NCBI chr15:76,078,024...76,127,778
Ensembl chr15:75,749,278...76,645,302

G

PC-esterase domain containing 1A

increases methylation

ISO

Methapyrilene results in increased methylation of PCED1A exon

NCBI chr 3:138,049,747...138,076,107
Ensembl chr 3:138,067,891...138,075,146

G

PCF11 cleavage and polyadenylation factor subunit

increases expression

EXP

Methapyrilene results in increased expression of PCF11 mRNA

NCBI chr 1:156,109,724...156,136,950
Ensembl chr 1:156,109,724...156,136,435

G

polycomb group ring finger 3

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of PCGF3 mRNA
Methapyrilene results in increased methylation of PCGF3 intron

PMID:30157460 PMID:30467583

NCBI chr14:1,381,976...1,436,709
Ensembl chr14:1,381,380...1,436,912

G

polycomb group ring finger 6

decreases expression

EXP

Methapyrilene results in decreased expression of PCGF6 mRNA

NCBI chr 1:255,866,709...255,886,306
Ensembl chr 1:255,866,711...255,886,266

G

phosphoenolpyruvate carboxykinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PCK1 mRNA

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

EXP

Methapyrilene results in increased expression of PCK2 mRNA

NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864

G

piccolo (presynaptic cytomatrix protein)

decreases methylation

ISO

Methapyrilene results in decreased methylation of PCLO intron

NCBI chr 4:20,646,604...21,005,171
Ensembl chr 4:20,646,604...21,005,111

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of PCMT1 intron

NCBI chr 1:3,932,161...3,980,751
Ensembl chr 1:3,932,161...3,964,848

G

proliferating cell nuclear antigen

increases expression

EXP

Methapyrilene results in increased expression of PCNA mRNA

PMID:15890375 PMID:30467583

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

pecanex 2

increases methylation

ISO

Methapyrilene results in increased methylation of PCNX2 intron

NCBI chr19:70,616,240...70,766,869
Ensembl chr19:70,616,240...70,766,869

G

procollagen C-endopeptidase enhancer

decreases methylation

ISO

Methapyrilene results in decreased methylation of PCOLCE intron

NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287

G

proprotein convertase subtilisin/kexin type 2

increases methylation

EXP

Methapyrilene results in increased methylation of PCSK2 gene

NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849

G

proprotein convertase subtilisin/kexin type 5

increases methylation

ISO

Methapyrilene results in increased methylation of PCSK5 intron

NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:224,264,678...224,694,347

G

proprotein convertase subtilisin/kexin type 6

increases methylation

ISO

Methapyrilene results in increased methylation of PCSK6 intron

NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128

G

phosphatidylcholine transfer protein

decreases expression

EXP

Methapyrilene results in decreased expression of PCTP mRNA

NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432

G

prenylcysteine oxidase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PCYOX1 mRNA

NCBI chr 4:120,389,545...120,400,382
Ensembl chr 4:120,388,180...120,400,382

G

programmed cell death 1

affects methylation

ISO

Methapyrilene affects the methylation of PDCD1 3' UTR

NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:101,866,126...101,879,270

G

programmed cell death 4

decreases expression

ISO
EXP

Methapyrilene results in decreased expression of PDCD4 mRNA

PMID:21873647 PMID:30467583

NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189

G

programmed cell death 6

increases methylation

ISO

Methapyrilene results in increased methylation of PDCD6 intron

NCBI chr 1:30,795,105...30,810,771
Ensembl chr 1:30,795,040...30,810,773

G

programmed cell death 6 interacting protein

decreases expression

EXP

Methapyrilene results in decreased expression of PDCD6IP mRNA

NCBI chr 8:122,469,223...122,524,993
Ensembl chr 8:122,469,223...122,524,993

G

phosphodiesterase 1C

affects methylation
decreases methylation

ISO

Methapyrilene affects the methylation of PDE1C intron
Methapyrilene results in decreased methylation of PDE1C 3' UTR

NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:86,626,282...87,193,259

G

phosphodiesterase 2A

increases methylation

ISO

Methapyrilene results in increased methylation of PDE2A intron

NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466

G

phosphodiesterase 4A

increases methylation

ISO

Methapyrilene results in increased methylation of PDE4A intron

NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:27,966,996...28,046,924

G

phosphodiesterase 4B

increases methylation

ISO

Methapyrilene results in increased methylation of PDE4B intron

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267

G

phosphodiesterase 4C

decreases methylation

ISO

Methapyrilene results in decreased methylation of PDE4C intron

NCBI chr16:18,724,703...18,745,528
Ensembl chr16:18,725,674...18,744,037

G

phosphodiesterase 6A

increases methylation

ISO

Methapyrilene results in increased methylation of PDE6A intron

NCBI chr18:56,947,249...57,019,015
Ensembl chr18:56,947,249...57,019,015

G

phosphodiesterase 7A

decreases methylation

ISO

Methapyrilene results in decreased methylation of PDE7A intron

NCBI chr 2:103,631,655...103,723,057
Ensembl chr 2:103,634,594...103,722,890

G

phosphodiesterase 7B

increases methylation

ISO

Methapyrilene results in increased methylation of PDE7B intron

NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456

G

phosphodiesterase 8B

increases methylation

ISO

Methapyrilene results in increased methylation of PDE8B intron

NCBI chr 2:28,009,841...28,244,050
Ensembl chr 2:28,011,359...28,244,327

G

phosphodiesterase 9A

increases methylation

ISO

Methapyrilene results in increased methylation of PDE9A exon; Methapyrilene results in increased methylation of PDE9A intron

NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,471,167...9,564,286

G

protein disulfide isomerase family A, member 4

decreases expression

EXP

Methapyrilene results in decreased expression of PDIA4 mRNA

NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191

G

PDZ and LIM domain 2

increases methylation

ISO

Methapyrilene results in increased methylation of PDLIM2 intron

NCBI chr15:51,647,195...51,659,904
Ensembl chr15:51,647,197...51,658,958

G

PDZ and LIM domain 3

increases methylation

ISO

Methapyrilene results in increased methylation of PDLIM3 exon

NCBI chr16:53,085,020...53,116,495
Ensembl chr16:53,085,020...53,116,217

G

pyruvate dehydrogenase phosphatase catalytic subunit 1

increases expression

EXP

Methapyrilene results in increased expression of PDP1 mRNA

NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960

G

3-phosphoinositide dependent protein kinase-1

decreases expression

EXP

Methapyrilene results in decreased expression of PDPK1 mRNA

NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181

G

p53 and DNA damage regulated 1

increases expression

EXP

Methapyrilene results in increased expression of PDRG1 mRNA

NCBI chr 3:161,937,812...161,943,981
Ensembl chr 3:161,937,815...161,948,995

G

pyridoxal-dependent decarboxylase domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PDXDC1 intron

NCBI chr10:2,528,989...2,620,669
Ensembl chr10:2,532,485...2,620,669

G

pyridoxal kinase

increases expression

EXP

Methapyrilene results in increased expression of PDXK protein

NCBI chr20:10,209,975...10,232,012
Ensembl chr20:10,209,832...10,233,780

G

PDZ domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of PDZD2 intron

NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:63,111,650...63,497,478

G

PDZ domain containing 7

increases methylation

ISO

Methapyrilene results in increased methylation of PDZD7 intron

NCBI chr 1:253,837,454...253,856,919
Ensembl chr 1:253,837,459...253,855,999

G

PDZ domain containing RING finger 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of PDZRN3 exon

NCBI chr 4:135,327,082...135,553,294
Ensembl chr 4:135,327,082...135,553,294

G

peroxisomal trans-2-enoyl-CoA reductase

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of PECR mRNA
Methapyrilene results in decreased methylation of PECR intron

PMID:30157460 PMID:30467583

NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806

G

pellino E3 ubiquitin protein ligase 1

increases methylation

ISO

Methapyrilene results in increased methylation of PELI1 intron

NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466

G

pelota mRNA surveillance and ribosome rescue factor

increases methylation

ISO

Methapyrilene results in increased methylation of PELO exon

NCBI chr 2:48,530,902...48,532,670
Ensembl chr 2:48,530,907...48,532,761

G

phosphatidylethanolamine N-methyltransferase

increases methylation

ISO

Methapyrilene results in increased methylation of PEMT intron

NCBI chr10:45,275,434...45,349,651
Ensembl chr10:45,275,412...45,420,037

G

peptidase D

affects methylation

ISO

Methapyrilene affects the methylation of PEPD intron

NCBI chr 1:96,673,624...96,818,197
Ensembl chr 1:96,673,607...96,818,190

G

period circadian regulator 2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of PER2 mRNA
Methapyrilene results in increased methylation of PER2 intron

PMID:30157460 PMID:30467583

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993

G

peroxisomal biogenesis factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of PEX1 mRNA

NCBI chr 4:31,474,670...31,513,621
Ensembl chr 4:31,470,845...31,513,811

G

peroxisomal biogenesis factor 11 beta

decreases expression

EXP

Methapyrilene results in decreased expression of PEX11B mRNA

NCBI chr 2:186,858,222...186,869,814
Ensembl chr 2:186,860,912...186,869,800

G

peroxisomal biogenesis factor 13

decreases expression

EXP

Methapyrilene results in decreased expression of PEX13 mRNA

NCBI chr14:101,804,673...101,822,367
Ensembl chr14:101,804,673...101,822,367

G

peroxisomal biogenesis factor 14

decreases methylation

ISO

Methapyrilene results in decreased methylation of PEX14 intron

NCBI chr 5:164,682,876...164,819,352
Ensembl chr 5:164,682,715...164,819,352

G

peroxisomal biogenesis factor 2

decreases expression

EXP

Methapyrilene results in decreased expression of PEX2 mRNA

NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:97,948,443...97,981,092

G

peroxisomal biogenesis factor 7

decreases expression

EXP

Methapyrilene results in decreased expression of PEX7 mRNA

NCBI chr 1:16,402,319...16,466,304
Ensembl chr 1:16,402,320...16,466,366

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PFKFB1 mRNA

NCBI chr X:22,936,038...22,989,691
Ensembl chr X:22,937,494...22,989,704

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

affects methylation

ISO

Methapyrilene affects the methylation of PFKFB3 intron

NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of PFKFB4 polyA tail

NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:118,522,365...118,565,468

G

phosphofructokinase, liver type

increases methylation

ISO

Methapyrilene results in increased methylation of PFKL intron

NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966

G

phosphoglycerate mutase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PGAM1 mRNA

NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203

G

peptidoglycan recognition protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of PGLYRP2 intron

NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:12,069,414...12,078,369

G

phosphatase and actin regulator 1

affects methylation

ISO

Methapyrilene affects the methylation of PHACTR1 intron

NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586

G

phosphatase and actin regulator 4

increases methylation

ISO

Methapyrilene results in increased methylation of PHACTR4 promoter

NCBI chr 5:149,828,716...149,904,955
Ensembl chr 5:149,833,367...149,905,187

G

phagophore assembly factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PHAF1 promoter

NCBI chr19:50,011,350...50,050,880
Ensembl chr19:50,011,369...50,053,987

G

polyhomeotic homolog 3

increases methylation

ISO

Methapyrilene results in increased methylation of PHC3 intron

NCBI chr 2:114,337,180...114,412,132
Ensembl chr 2:114,337,227...114,405,816

G

PHD finger protein 14

decreases expression

EXP

Methapyrilene results in decreased expression of PHF14 mRNA

NCBI chr 4:40,975,897...41,162,043
Ensembl chr 4:40,975,439...41,162,043

G

PHD finger protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of PHF2 mRNA

NCBI chr17:15,989,594...16,057,583
Ensembl chr17:15,981,604...16,057,583

G

PHD finger protein 20

increases methylation

ISO

Methapyrilene results in increased methylation of PHF20 intron

NCBI chr 3:165,170,337...165,279,276
Ensembl chr 3:165,170,405...165,274,526

G

PHD finger protein 21B

decreases methylation

ISO

Methapyrilene results in decreased methylation of PHF21B intron

NCBI chr 7:117,793,643...117,864,141
Ensembl chr 7:117,794,046...117,864,141

G

PHD finger protein 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of PHF8 intron

NCBI chr X:23,967,126...24,066,473
Ensembl chr X:23,967,556...24,066,471

G

phosphoglycerate dehydrogenase

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of PHGDH mRNA
Methapyrilene results in decreased expression of PHGDH mRNA

PMID:15890375 PMID:22484513 PMID:30467583

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789

G

pleckstrin homology-like domain, family A, member 3

increases expression

EXP

Methapyrilene results in increased expression of PHLDA3 mRNA

NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621

G

pleckstrin homology-like domain, family B, member 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PHLDB1 exon

NCBI chr 8:53,900,338...53,948,325
Ensembl chr 8:53,900,338...53,949,518

G

pleckstrin homology-like domain, family B, member 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of PHLDB3 exon

NCBI chr 1:89,328,991...89,347,446
Ensembl chr 1:89,328,819...89,347,436

G

PH domain and leucine rich repeat protein phosphatase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PHLPP1 intron

NCBI chr13:22,823,132...23,045,619
Ensembl chr13:22,823,132...23,045,619

G

phytanoyl-CoA 2-hydroxylase

decreases expression

EXP

Methapyrilene results in decreased expression of PHYH mRNA

NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645

G

phytanoyl-CoA dioxygenase domain containing 1

increases expression

EXP

Methapyrilene results in increased expression of PHYHD1 mRNA

NCBI chr 3:33,933,487...33,951,614
Ensembl chr 3:33,937,898...33,951,614

G

phosphatidylinositol 4-kinase alpha

decreases expression

EXP

Methapyrilene results in decreased expression of PI4KA mRNA

NCBI chr11:97,113,390...97,234,374
Ensembl chr11:97,113,245...97,228,315

G

phosphotyrosine interaction domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PID1 intron

NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070

G

piezo-type mechanosensitive ion channel component 1

increases methylation

ISO

Methapyrilene results in increased methylation of PIEZO1 polyA tail

NCBI chr19:67,453,120...67,515,347
Ensembl chr19:67,453,122...67,515,037

G

piezo-type mechanosensitive ion channel component 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PIEZO2 exon

NCBI chr18:58,738,734...59,115,252
Ensembl chr18:58,738,740...59,115,215

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of PIK3C3 intron

NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

increases methylation

ISO

Methapyrilene results in increased methylation of PIK3CD exon; Methapyrilene results in increased methylation of PIK3CD intron

NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968

G

phosphoinositide-3-kinase, regulatory subunit 5

increases methylation

ISO

Methapyrilene results in increased methylation of PIK3R5 intron

NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539

G

phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

decreases methylation

ISO

Methapyrilene results in decreased methylation of PIP4K2A intron

NCBI chr17:86,405,080...86,576,597
Ensembl chr17:86,405,081...86,576,430

G

phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2

decreases expression

EXP

Methapyrilene results in decreased expression of PIP4P2 mRNA

NCBI chr 5:33,057,046...33,104,448
Ensembl chr 5:33,056,684...33,104,451

G

pirin

increases methylation

ISO

Methapyrilene results in increased methylation of PIR intron

NCBI chr X:33,740,428...33,851,049
Ensembl chr X:33,740,429...33,851,049

G

phosphatidylinositol transfer protein, cytoplasmic 1

increases methylation

ISO

Methapyrilene results in increased methylation of PITPNC1 intron

NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344

G

PITPNM family member 3

increases methylation

ISO

Methapyrilene results in increased methylation of PITPNM3 intron

NCBI chr10:57,173,230...57,265,186
Ensembl chr10:57,175,721...57,265,291

G

praja ring finger ubiquitin ligase 2

decreases expression

EXP

Methapyrilene results in decreased expression of PJA2 mRNA

NCBI chr 9:111,403,624...111,453,703
Ensembl chr 9:111,403,624...111,453,703

G

polycystin 1 like 1, transient receptor potential channel interacting

decreases methylation

ISO

Methapyrilene results in decreased methylation of PKD1L1 intron

NCBI chr14:87,766,745...87,888,647
Ensembl chr14:87,760,208...87,852,259

G

polycystin 1 like 2

affects methylation

ISO

Methapyrilene affects the methylation of PKD1L2 intron

NCBI chr19:61,958,351...62,045,324
Ensembl chr19:61,958,415...62,044,358

G

protein kinase domain containing, cytoplasmic

decreases methylation

ISO

Methapyrilene results in decreased methylation of PKDCC intron

NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042

G

cAMP-dependent protein kinase inhibitor gamma

decreases methylation

ISO

Methapyrilene results in decreased methylation of PKIG intron

NCBI chr 3:172,749,871...172,817,514
Ensembl chr 3:172,749,928...172,817,519

G

pyruvate kinase L/R

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of PKLR mRNA
Methapyrilene results in decreased expression of PKLR mRNA

PMID:22484513 PMID:28903497

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644

G

pyruvate kinase M1/2

decreases expression

EXP

Methapyrilene results in decreased expression of PKM mRNA

NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396

G

PBX/knotted 1 homeobox 2

increases methylation

ISO

Methapyrilene results in increased methylation of PKNOX2 intron

NCBI chr 8:44,789,464...45,051,933
Ensembl chr 8:44,789,467...44,979,754

G

plakophilin 1

affects methylation

ISO

Methapyrilene affects the methylation of PKP1 intron

NCBI chr13:49,861,340...49,909,162
Ensembl chr13:49,861,340...49,909,162

G

phospholipase A2, group XIIA

increases expression

EXP

Methapyrilene results in increased expression of PLA2G12A mRNA

NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964

G

phospholipase A2, group IIF

increases methylation

ISO

Methapyrilene results in increased methylation of PLA2G2F 3' UTR

NCBI chr 5:156,270,077...156,276,464
Ensembl chr 5:156,270,077...156,295,516

G

phospholipase A2 group IVC

increases methylation

ISO

Methapyrilene results in increased methylation of PLA2G4C intron

NCBI chr 1:83,315,017...83,411,342
Ensembl chr 1:83,382,068...83,410,037

G

phospholipase A2, group V

increases methylation

ISO

Methapyrilene results in increased methylation of PLA2G5 intron

NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:156,324,629...156,381,926

G

PLAG1 zinc finger

decreases methylation

ISO

Methapyrilene results in decreased methylation of PLAG1 intron

NCBI chr 5:21,699,650...21,754,325
Ensembl chr 5:21,702,987...21,711,240

G

phospholipase B1

increases methylation

ISO

Methapyrilene results in increased methylation of PLB1 intron

NCBI chr 6:29,807,127...29,945,607
Ensembl chr 6:29,809,290...29,930,183

G

phospholipase B domain containing 1

increases expression

EXP

Methapyrilene results in increased expression of PLBD1 mRNA

NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488

G

phospholipase C beta 1

increases methylation

ISO

Methapyrilene results in increased methylation of PLCB1 intron

NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646

G

phospholipase C, delta 3

increases methylation

ISO

Methapyrilene results in increased methylation of PLCD3 exon

NCBI chr10:88,526,802...88,548,116
Ensembl chr10:88,526,802...88,548,069

G

phospholipase C, epsilon 1

decreases methylation
decreases expression

EXP

Methapyrilene results in decreased methylation of PLCE1 gene
Methapyrilene results in decreased expression of PLCE1 mRNA

PMID:26431795 PMID:30467583

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828

G

phospholipase C, gamma 2

increases methylation

ISO

Methapyrilene results in increased methylation of PLCG2 exon; Methapyrilene results in increased methylation of PLCG2 intron

NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684

G

phospholipase C, eta 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PLCH2 intron

NCBI chr 5:170,826,543...170,885,012
Ensembl chr 5:170,826,543...170,885,152

G

phospholipase D family, member 4

increases expression

EXP

Methapyrilene results in increased expression of PLD4 mRNA

NCBI chr 6:137,639,948...137,647,462
Ensembl chr 6:137,639,945...137,649,024

G

phospholipase D family, member 5

affects methylation

ISO

Methapyrilene affects the methylation of PLD5 intron

NCBI chr13:90,426,689...90,765,072
Ensembl chr13:90,428,490...90,783,066

G

pleckstrin homology domain containing A1

decreases expression

EXP

Methapyrilene results in decreased expression of PLEKHA1 mRNA

NCBI chr 1:194,858,239...194,909,418
Ensembl chr 1:194,851,547...194,909,413

G

pleckstrin homology domain containing A5

decreases methylation

ISO

Methapyrilene results in decreased methylation of PLEKHA5 intron

NCBI chr 4:175,065,011...175,234,672
Ensembl chr 4:175,065,183...175,234,672

G

pleckstrin homology and RhoGEF domain containing G1

increases methylation

ISO

Methapyrilene results in increased methylation of PLEKHG1 intron

NCBI chr 1:42,612,023...42,841,727
Ensembl chr 1:42,612,122...42,841,719

G

pleckstrin homology and RhoGEF domain containing G5

increases methylation

ISO

Methapyrilene results in increased methylation of PLEKHG5 intron

NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229

G

pleckstrin homology, MyTH4 and FERM domain containing H2

increases methylation

ISO

Methapyrilene results in increased methylation of PLEKHH2 intron

NCBI chr 6:15,783,179...15,893,479
Ensembl chr 6:15,784,645...15,893,537

G

pleckstrin homology, MyTH4 and FERM domain containing H3

increases methylation

ISO

Methapyrilene results in increased methylation of PLEKHH3 exon

NCBI chr10:86,598,749...86,607,482
Ensembl chr10:86,598,754...86,607,165

G

pleckstrin homology domain containing S1

increases methylation

ISO

Methapyrilene results in increased methylation of PLEKHS1 polyA tail

NCBI chr 1:265,500,524...265,533,352
Ensembl chr 1:265,500,830...265,533,350

G

plasminogen

increases methylation

ISO

Methapyrilene results in increased methylation of PLG intron

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

perilipin 2

increases expression

EXP

Methapyrilene results in increased expression of PLIN2 mRNA

NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878

G

polo-like kinase 2

increases expression

EXP

Methapyrilene results in increased expression of PLK2 mRNA

NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296

G

phospholamban

increases expression

EXP

Methapyrilene results in increased expression of PLN mRNA

NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241

G

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

increases methylation

ISO

Methapyrilene results in increased methylation of PLOD1 intron

NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110

G

phospholipid phosphatase 2

increases methylation

ISO

Methapyrilene results in increased methylation of PLPP2 promoter

NCBI chr 7:10,826,534...10,834,628
Ensembl chr 7:10,826,549...10,834,627

G

phospholipid phosphatase 3

decreases expression

EXP

Methapyrilene results in decreased expression of PPAP2B mRNA

NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667

G

phospholipid phosphatase 5

decreases expression

EXP

Methapyrilene results in decreased expression of PLPP5 mRNA

NCBI chr16:73,052,204...73,056,609
Ensembl chr16:73,052,204...73,056,643

G

phospholipid phosphatase 6

decreases expression

EXP

Methapyrilene results in decreased expression of PLPP6 mRNA

NCBI chr 1:236,092,642...236,095,494
Ensembl chr 1:236,090,364...236,101,554

G

phospholipid phosphatase related 2

increases methylation

ISO

Methapyrilene results in increased methylation of PLPPR2 intron

NCBI chr 8:28,742,787...28,755,555
Ensembl chr 8:28,745,639...28,755,555

G

plastin 3

increases methylation

ISO

Methapyrilene results in increased methylation of PLS3 intron

NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893

G

plasmalemma vesicle associated protein

increases methylation

ISO

Methapyrilene results in increased methylation of PLVAP intron

NCBI chr16:18,218,966...18,231,279
Ensembl chr16:18,218,967...18,231,454

G

plexin A2

increases methylation

ISO

Methapyrilene results in increased methylation of PLXNA2 intron

NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453

G

plexin B2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PLXNB2 intron

NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746

G

plexin D1

increases methylation

ISO

Methapyrilene results in increased methylation of PLXND1 intron

NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:150,675,377...150,715,566

G

peptidase M20 domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of PM20D1 intron

NCBI chr13:45,790,161...45,812,206
Ensembl chr13:45,790,179...45,812,206

G

phosphomevalonate kinase

increases expression

EXP

Methapyrilene results in increased expression of PMVK mRNA

NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080

G

patatin-like phospholipase domain containing 7

decreases expression

EXP

Methapyrilene results in decreased expression of PNPLA7 mRNA

NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672

G

pyridoxamine 5'-phosphate oxidase

decreases expression

EXP

Methapyrilene results in decreased expression of PNPO mRNA

NCBI chr10:82,421,027...82,427,288
Ensembl chr10:82,421,027...82,427,288

G

polyribonucleotide nucleotidyltransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PNPT1 mRNA

NCBI chr14:107,078,486...107,109,628
Ensembl chr14:107,078,469...107,109,628

G

podocalyxin-like

increases methylation

ISO

Methapyrilene results in increased methylation of PODXL intron

NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789

G

protein O-glucosyltransferase 2

decreases expression

EXP

Methapyrilene results in decreased expression of POGLUT2 mRNA

NCBI chr 9:53,748,484...53,801,453
Ensembl chr 9:53,740,998...53,760,588

G

DNA polymerase delta 1, catalytic subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of POLD1 intron

NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982

G

DNA polymerase delta 2, accessory subunit

increases methylation

ISO

Methapyrilene results in increased methylation of POLD2 exon

NCBI chr14:84,962,933...84,969,148
Ensembl chr14:84,962,022...84,967,874

G

RNA polymerase I subunit A

decreases methylation

ISO

Methapyrilene results in decreased methylation of POLR1A exon

NCBI chr 4:105,508,305...105,572,272
Ensembl chr 4:105,508,248...105,574,036

G

RNA polymerase I and III subunit D

increases expression

EXP

Methapyrilene results in increased expression of POLR1D mRNA

NCBI chr12:13,084,505...13,118,069
Ensembl chr12:13,084,512...13,095,627

G

RNA polymerase II subunit D

increases expression

EXP

Methapyrilene results in increased expression of POLR2D mRNA

NCBI chr18:23,692,578...23,699,709
Ensembl chr18:23,692,578...23,699,709

G

RNA polymerase II, I and III subunit F

increases methylation

ISO

Methapyrilene results in increased methylation of POLR2F polyA tail

NCBI chr 7:112,592,977...112,604,681
Ensembl chr 7:112,593,027...112,604,666

G

RNA polymerase III subunit E

increases methylation

ISO

Methapyrilene results in increased methylation of POLR3E intron

NCBI chr 1:184,897,383...184,925,547
Ensembl chr 1:184,897,426...184,926,534

G

RNA polymerase III subunit G

increases methylation

ISO

Methapyrilene results in increased methylation of POLR3G intron

NCBI chr 2:13,680,893...13,721,802
Ensembl chr 2:13,680,895...13,721,802

G

paraoxonase 1

increases expression

EXP

Methapyrilene results in increased expression of PON1 mRNA

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924

G

POP1 homolog, ribonuclease P/MRP subunit

increases methylation

ISO

Methapyrilene results in increased methylation of POP1 intron

NCBI chr 7:67,590,502...67,618,187
Ensembl chr 7:67,590,522...67,618,293

G

popeye domain cAMP effector 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of POPDC2 exon

NCBI chr11:75,850,068...75,897,094
Ensembl chr11:75,880,274...75,896,269

G

cytochrome p450 oxidoreductase

increases expression

EXP

Methapyrilene results in increased expression of POR mRNA

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809

G

POTE ankyrin domain family, member G

increases methylation

ISO

Methapyrilene results in increased methylation of POTEG promoter

NCBI chr16:71,191,509...71,373,328
Ensembl chr16:71,334,466...71,373,280

G

POU class 6 homeobox 2

increases methylation

ISO

Methapyrilene results in increased methylation of POU6F2 intron

NCBI chr17:51,040,522...51,616,716
Ensembl chr17:51,167,771...51,616,597

G

peroxisome proliferator activated receptor alpha

decreases expression

EXP

Methapyrilene results in decreased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

phosphopantothenoylcysteine synthetase

increases methylation

ISO

Methapyrilene results in increased methylation of PPCS promoter

NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:138,308,397...138,312,012

G

PPFIA binding protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of PPFIBP1 mRNA

NCBI chr 4:181,538,249...181,682,079
Ensembl chr 4:181,539,450...181,682,076

G

periphilin 1

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of PPHLN1 mRNA
Methapyrilene results in decreased methylation of PPHLN1 polyA tail

PMID:30157460 PMID:30467583

NCBI chr 7:126,418,042...126,509,430
Ensembl chr 7:126,417,555...126,509,430

G

protein phosphatase, Mg2+/Mn2+ dependent, 1B

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of PPM1B intron
Methapyrilene results in decreased expression of PPM1B mRNA

PMID:30157460 PMID:30467583

NCBI chr 6:15,399,559...15,460,301
Ensembl chr 6:15,399,562...15,460,756

G

protein phosphatase, Mg2+/Mn2+ dependent, 1L

decreases expression

EXP

Methapyrilene results in decreased expression of PPM1L mRNA

NCBI chr 2:155,876,605...156,149,371
Ensembl chr 2:155,876,605...156,149,371

G

protein phosphatase methylesterase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PPME1 intron

NCBI chr 1:164,080,242...164,127,261
Ensembl chr 1:164,080,242...164,127,220

G

protein phosphatase 1, regulatory (inhibitor) subunit 14c

increases methylation

ISO

Methapyrilene results in increased methylation of PPP1R14C intron

NCBI chr 1:42,177,977...42,358,654
Ensembl chr 1:42,179,523...42,376,419

G

protein phosphatase 1, regulatory subunit 15A

increases expression

EXP

Methapyrilene results in increased expression of PPP1R15A mRNA

PMID:16393664 PMID:17450226 PMID:23274394 PMID:30467583

NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774

G

protein phosphatase 1, regulatory subunit 15B

decreases expression

EXP

Methapyrilene results in decreased expression of PPP1R15B mRNA

NCBI chr13:47,130,000...47,137,805
Ensembl chr13:47,129,967...47,137,798

G

protein phosphatase 1, regulatory (inhibitor) subunit 2

increases expression

EXP

Methapyrilene results in increased expression of PPP1R2 mRNA

NCBI chr11:82,977,634...82,999,426
Ensembl chr11:82,977,515...83,001,083

G

protein phosphatase 1, regulatory subunit 9A

increases methylation

ISO

Methapyrilene results in increased methylation of PPP1R9A intron

NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927

G

protein phosphatase 2 scaffold subunit A beta

increases expression

EXP

Methapyrilene results in increased expression of PPP2R1B mRNA

NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:60,081,553...60,125,795

G

protein phosphatase 2, regulatory subunit B, alpha

increases expression

EXP

Methapyrilene results in increased expression of PPP2R2A mRNA

NCBI chr15:45,380,142...45,439,428
Ensembl chr15:45,379,683...45,439,405

G

protein phosphatase 2, regulatory subunit B, beta

increases methylation

ISO

Methapyrilene results in increased methylation of PPP2R2B intron

NCBI chr18:34,904,686...35,357,299
Ensembl chr18:34,904,686...35,356,977

G

protein phosphatase 2, regulatory subunit B, gamma

increases methylation

ISO

Methapyrilene results in increased methylation of PPP2R2C intron

NCBI chr14:78,071,274...78,156,212
Ensembl chr14:78,071,274...78,156,212

G

protein phosphatase 2, regulatory subunit B'', alpha

increases methylation

ISO

Methapyrilene results in increased methylation of PPP2R3A intron

NCBI chr 8:110,582,479...110,720,516
Ensembl chr 8:110,583,743...110,677,482

G

protein phosphatase 2 regulatory subunit B', epsilon

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of PPP2R5E intron
Methapyrilene results in decreased expression of PPP2R5E mRNA

PMID:30157460 PMID:30467583

NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573

G

protein phosphatase 3 catalytic subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of PPP3CA mRNA

NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554

G

protein phosphatase 3 catalytic subunit beta

decreases expression

EXP

Methapyrilene results in decreased expression of PPP3CB mRNA

NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203

G

protein phosphatase 4, regulatory subunit 2

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of PPP4R2 mRNA
Methapyrilene results in decreased methylation of PPP4R2 intron

PMID:30157460 PMID:30467583

NCBI chr 4:135,010,919...135,051,844
Ensembl chr 4:135,010,919...135,051,844

G

protein phosphatase 6, catalytic subunit

increases methylation

ISO

Methapyrilene results in increased methylation of PPP6C intron

NCBI chr 3:43,339,521...43,371,807
Ensembl chr 3:43,341,108...43,371,807

G

protein phosphatase 6, regulatory subunit 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PPP6R1 intron

NCBI chr 1:78,218,629...78,246,360
Ensembl chr 1:78,219,154...78,246,350

G

palmitoyl-protein thioesterase 1

increases methylation

ISO

Methapyrilene results in increased methylation of PPT1 intron

NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:140,406,214...140,427,200

G

PR/SET domain 11

increases methylation

ISO

Methapyrilene results in increased methylation of PRDM11 3' UTR

NCBI chr 3:99,381,093...99,460,805
Ensembl chr 3:99,387,518...99,460,962

G

PR/SET domain 15

increases methylation

ISO

Methapyrilene results in increased methylation of PRDM15 intron

NCBI chr11:50,633,973...50,691,624
Ensembl chr11:50,633,973...50,691,823

G

PR/SET domain 16

affects methylation
increases methylation

ISO

Methapyrilene affects the methylation of PRDM16 intron
Methapyrilene results in increased methylation of PRDM16 exon

NCBI chr 5:170,162,275...170,486,371
Ensembl chr 5:170,162,275...170,485,804

G

PR/SET domain 6

increases methylation

ISO

Methapyrilene results in increased methylation of PRDM6 intron

NCBI chr18:49,102,290...49,206,763
Ensembl chr18:49,102,641...49,206,761

G

peroxiredoxin 2

increases expression

EXP

Methapyrilene results in increased expression of PRDX2 mRNA

NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006

G

peroxiredoxin 3

increases expression

EXP

Methapyrilene results in increased expression of PRDX3 mRNA

NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300

G

proline and arginine rich end leucine rich repeat protein

increases methylation

ISO

Methapyrilene results in increased methylation of PRELP 3' UTR

NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324

G

prolyl endopeptidase-like

decreases expression

EXP

Methapyrilene results in decreased expression of PREPL mRNA

NCBI chr 6:15,333,107...15,362,825
Ensembl chr 6:15,333,077...15,363,231

G

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PREX1 exon; Methapyrilene results in decreased methylation of PREX1 intron

NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764

G

proteoglycan 3, pro eosinophil major basic protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of PRG3 intron

NCBI chr 3:90,478,627...90,484,760
Ensembl chr 3:90,479,154...90,484,759

G

protein kinase AMP-activated catalytic subunit alpha 2

decreases expression

EXP

Methapyrilene results in decreased expression of PRKAA2 mRNA

NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324

G

protein kinase AMP-activated non-catalytic subunit gamma 2

increases methylation

ISO

Methapyrilene results in increased methylation of PRKAG2 intron

NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939

G

protein kinase cAMP-dependent type I regulatory subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of PRKAR1A mRNA

NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025

G

protein kinase cAMP-dependent type I regulatory subunit beta

increases methylation

ISO

Methapyrilene results in increased methylation of PRKAR1B intron

NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766

G

protein kinase cAMP-dependent type II regulatory subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of PRKAR2A mRNA

NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330

G

protein kinase C, alpha

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRKCA intron

NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572

G

protein kinase C, beta

decreases expression

EXP

Methapyrilene results in decreased expression of PRKCB mRNA

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740

G

protein kinase C, epsilon

increases methylation

ISO

Methapyrilene results in increased methylation of PRKCE intron

NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288

G

protein kinase C, eta

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRKCH promoter

NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:98,027,646...98,226,477

G

protein kinase C, theta

increases methylation

ISO

Methapyrilene results in increased methylation of PRKCQ intron

NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508

G

protein kinase C, zeta

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRKCZ intron

NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674

G

protein kinase D1

increases methylation

ISO

Methapyrilene results in increased methylation of PRKD1 intron

NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509

G

protein kinase D3

decreases expression

EXP

Methapyrilene results in decreased expression of PRKD3 mRNA

NCBI chr 6:21,784,665...21,860,600
Ensembl chr 6:21,784,673...21,860,600

G

protein kinase, DNA-activated, catalytic subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRKDC intron

NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108

G

protein kinase cGMP-dependent 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRKG1 intron

NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005

G

parkin RBR E3 ubiquitin protein ligase

increases methylation

ISO

Methapyrilene results in increased methylation of PRKN intron

NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304

G

prion like protein doppel

increases methylation

ISO

Methapyrilene results in increased methylation of PRND promoter

NCBI chr 3:139,666,383...139,671,647
Ensembl chr 3:139,666,068...139,671,890

G

prion protein

increases expression

EXP

Methapyrilene results in increased expression of PRNP mRNA

NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436

G

protein interacting with cyclin A1

decreases methylation

ISO

Methapyrilene results in decreased methylation of PROCA1 intron

NCBI chr10:63,588,061...63,601,011
Ensembl chr10:63,588,028...63,601,095

G

prominin 1

increases expression

ISO

Methapyrilene results in increased expression of PROM1 mRNA

NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002

G

protein only RNase P catalytic subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRORP intron

NCBI chr 6:78,404,821...78,497,562
Ensembl chr 6:78,405,980...78,497,761

G

prolyl-tRNA synthetase associated domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of PRORSD1 mRNA

NCBI chr14:107,458,910...107,461,179
Ensembl chr14:107,458,857...107,461,205

G

protein S

decreases expression

EXP

Methapyrilene results in decreased expression of PROS1 mRNA

NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852

G

prospero homeobox 1

decreases expression

EXP

Methapyrilene results in decreased expression of PROX1 mRNA

NCBI chr13:104,196,615...104,251,007
Ensembl chr13:104,200,378...104,250,975

G

pre-mRNA processing factor 4B

decreases expression

EXP

Methapyrilene results in decreased expression of PRPF4B mRNA

NCBI chr17:30,190,721...30,230,153
Ensembl chr17:30,193,907...30,225,420

G

pre-mRNA processing factor 8

decreases expression

EXP

Methapyrilene results in decreased expression of PRPF8 mRNA

NCBI chr10:60,829,778...60,852,887
Ensembl chr10:60,829,778...60,852,887

G

phosphoribosyl pyrophosphate synthetase 2

increases methylation

ISO

Methapyrilene results in increased methylation of PRPS2 intron

NCBI chr X:30,592,845...30,630,127
Ensembl chr X:30,593,019...30,630,126

G

proline rich 12

affects methylation

ISO

Methapyrilene affects the methylation of PRR12 intron

NCBI chr 1:104,646,492...104,670,454
Ensembl chr 1:104,646,492...104,670,454

G

proline rich 5

affects methylation

ISO

Methapyrilene affects the methylation of PRR5 intron

NCBI chr 7:117,675,308...117,717,833
Ensembl chr 7:117,675,383...117,717,831

G

proline rich 5 like

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRR5L intron

NCBI chr 3:108,458,107...108,628,552
Ensembl chr 3:108,458,633...108,537,763

G

proline-rich coiled-coil 2A

increases methylation

ISO

Methapyrilene results in increased methylation of PRRC2A exon

NCBI chr20:3,660,981...3,686,715
Ensembl chr20:3,663,400...3,678,778

G

paired related homeobox 2

increases methylation

ISO

Methapyrilene results in increased methylation of PRRX2 intron

NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:34,520,173...34,566,284

G

phosphoribosyl transferase domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of PRTFDC1 mRNA

NCBI chr17:88,457,872...88,563,109
Ensembl chr17:88,457,872...88,563,066

G

periaxin

decreases methylation

ISO

Methapyrilene results in decreased methylation of PRX exon

NCBI chr 1:91,912,669...91,934,754
Ensembl chr 1:91,911,999...91,937,235

G

prostate stem cell antigen

increases methylation

ISO

Methapyrilene results in increased methylation of PSCA intron

NCBI chr 7:108,483,974...108,492,098
Ensembl chr 7:108,484,184...108,492,097

G

pleckstrin and Sec7 domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of PSD2 intron

NCBI chr18:27,838,943...27,890,712
Ensembl chr18:27,839,627...27,890,709

G

PC4 and SRSF1 interacting protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of PSIP1 mRNA

NCBI chr 5:102,892,929...102,925,191
Ensembl chr 5:102,892,932...102,925,170

G

proteasome 20S subunit alpha 1

increases expression

EXP

Methapyrilene results in increased expression of PSMA1 mRNA

NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:177,875,353...177,887,949

G

proteasome 20S subunit alpha 2

increases expression

EXP

Methapyrilene results in increased expression of PSMA2 mRNA

NCBI chr17:55,250,054...55,260,441
Ensembl chr17:55,247,442...55,339,673

G

proteasome 20S subunit alpha 4

increases expression

EXP

Methapyrilene results in increased expression of PSMA4 mRNA

NCBI chr 8:64,236,520...64,243,980
Ensembl chr 8:64,236,783...64,243,979

G

proteasome 20S subunit alpha 5

increases expression

EXP

Methapyrilene results in increased expression of PSMA5 mRNA

NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867

G

proteasome 20S subunit alpha 7

increases expression

EXP

Methapyrilene results in increased expression of PSMA7 mRNA

NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253

G

proteasome 20S subunit alpha 8

increases methylation

ISO

Methapyrilene results in increased methylation of PSMA8 intron

NCBI chr18:6,138,226...6,202,802
Ensembl chr18:6,138,226...6,202,802

G

proteasome 20S subunit beta 1

increases expression

EXP

Methapyrilene results in increased expression of PSMB1 mRNA

NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640

G

proteasome 20S subunit beta 3

increases expression

EXP

Methapyrilene results in increased expression of PSMB3 mRNA

NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883

G

proteasome 20S subunit beta 4

increases expression

EXP

Methapyrilene results in increased expression of PSMB4 mRNA

NCBI chr 2:185,131,787...185,134,561
Ensembl chr 2:185,131,786...185,135,287

G

proteasome 20S subunit beta 5

increases expression

EXP

Methapyrilene results in increased expression of PSMB5 mRNA

NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379

G

proteasome 26S subunit, ATPase 1

decreases expression

EXP

Methapyrilene results in decreased expression of PSMC1 mRNA

NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858

G

proteasome 26S subunit, ATPase 2

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of PSMC2 mRNA
Methapyrilene results in decreased expression of PSMC2 protein

PMID:15890375 PMID:30467583

NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390

G

proteasome 26S subunit, ATPase 4

increases expression

EXP

Methapyrilene results in increased expression of PSMC4 mRNA

NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060

G

proteasome 26S subunit, ATPase 5

increases expression

EXP

Methapyrilene results in increased expression of PSMC5 mRNA

NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921

G

proteasome 26S subunit, non-ATPase 1

increases expression

EXP

Methapyrilene results in increased expression of PSMD1 mRNA

NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218

G

proteasome 26S subunit, non-ATPase 11

increases expression

EXP

Methapyrilene results in increased expression of PSMD11 mRNA

NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234

G

proteasome 26S subunit, non-ATPase 3

increases methylation

ISO

Methapyrilene results in increased methylation of PSMD3 3' UTR

NCBI chr10:84,139,249...84,151,879
Ensembl chr10:84,139,677...84,151,878

G

proteasome activator subunit 3

increases expression

EXP

Methapyrilene results in increased expression of PSME3 mRNA

NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033

G

proteasome activator subunit 4

decreases expression

EXP

Methapyrilene results in decreased expression of PSME4 mRNA

NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328

G

paraspeckle component 1

increases expression
decreases methylation

EXP
ISO

Methapyrilene results in increased expression of PSPC1 mRNA
Methapyrilene results in decreased methylation of PSPC1 intron

PMID:30157460 PMID:30467583

NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828

G

proline-serine-threonine phosphatase-interacting protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PSTPIP2 intron

NCBI chr18:73,585,729...73,671,868
Ensembl chr18:73,585,993...73,671,871

G

phosphatidylserine synthase 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of PTDSS2 intron

NCBI chr 1:205,671,024...205,695,556
Ensembl chr 1:205,671,041...205,695,553

G

prostaglandin E receptor 3

increases methylation

ISO

Methapyrilene results in increased methylation of PTGER3 intron

NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:249,264,985...249,409,846

G

prostaglandin reductase 2

decreases expression

EXP

Methapyrilene results in decreased expression of PTGR2 mRNA

NCBI chr 6:109,662,469...109,694,232
Ensembl chr 6:109,662,498...109,694,232

G

prostaglandin reductase 3

decreases expression

EXP

Methapyrilene results in decreased expression of PTGR3 mRNA

NCBI chr18:79,729,282...79,738,632
Ensembl chr18:79,729,282...79,738,632

G

prostaglandin-endoperoxide synthase 1

increases methylation

ISO

Methapyrilene results in increased methylation of PTGS1 intron

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990

G

protein tyrosine kinase 2 beta

increases methylation

ISO

Methapyrilene results in increased methylation of PTK2B exon; Methapyrilene results in increased methylation of PTK2B intron

NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806

G

protein tyrosine phosphatase 4A1

increases expression

EXP

Methapyrilene results in increased expression of PTP4A1 mRNA

NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176

G

protein tyrosine phosphatase, non-receptor type 11

decreases methylation

ISO

Methapyrilene results in decreased methylation of PTPN11 intron

NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577

G

protein tyrosine phosphatase, non-receptor type 21

decreases expression

EXP

Methapyrilene results in decreased expression of PTPN21 mRNA

NCBI chr 6:123,662,783...123,727,809
Ensembl chr 6:123,662,783...123,727,809

G

protein tyrosine phosphatase, non-receptor type 3

decreases expression

EXP

Methapyrilene results in decreased expression of PTPN3 mRNA

NCBI chr 5:76,703,687...76,822,584
Ensembl chr 5:76,703,687...76,860,470

G

protein tyrosine phosphatase, non-receptor type 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of PTPN7 intron

NCBI chr13:49,122,679...49,136,096
Ensembl chr13:49,122,609...49,136,094

G

protein tyrosine phosphatase, receptor type, D

increases methylation

ISO

Methapyrilene results in increased methylation of PTPRD intron

NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903

G

protein tyrosine phosphatase, receptor type, E

decreases methylation

ISO

Methapyrilene results in decreased methylation of PTPRE promoter

NCBI chr 1:199,774,195...199,924,646
Ensembl chr 1:199,774,198...199,922,242

G

protein tyrosine phosphatase, receptor type, F

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of PTPRF mRNA
Methapyrilene results in increased methylation of PTPRF intron

PMID:30157460 PMID:30467583

NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426

G

protein tyrosine phosphatase, receptor type, G

decreases expression

EXP

Methapyrilene results in decreased expression of PTPRG mRNA

NCBI chr15:15,298,669...15,982,581
Ensembl chr15:15,302,133...15,982,668

G

protein tyrosine phosphatase, receptor type, H

decreases methylation

ISO

Methapyrilene results in decreased methylation of PTPRH exon

NCBI chr 1:78,272,414...78,318,977
Ensembl chr 1:78,271,276...78,318,977

G

protein tyrosine phosphatase, receptor type, J

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of PTPRJ mRNA
Methapyrilene results in decreased methylation of PTPRJ intron

PMID:30157460 PMID:30467583

NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:96,861,785...97,017,656

G

protein tyrosine phosphatase, receptor type, K

decreases expression

EXP

Methapyrilene results in decreased expression of PTPRK mRNA

NCBI chr 1:18,557,091...19,056,297
Ensembl chr 1:18,558,365...19,056,107

G

protein tyrosine phosphatase, receptor type, M

decreases methylation

ISO

Methapyrilene results in decreased methylation of PTPRM intron

NCBI chr 9:114,086,380...114,791,000
Ensembl chr 9:114,086,380...114,790,477

G

protein tyrosine phosphatase, receptor type N2

affects methylation

ISO

Methapyrilene affects the methylation of PTPRN2 intron

NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744

G

protein tyrosine phosphatase, receptor type, S

increases expression

EXP

Methapyrilene results in increased expression of PTPRS mRNA

NCBI chr 9:1,332,558...1,394,161
Ensembl chr 9:1,332,559...1,394,093

G

PTTG1 regulator of sister chromatid separation, securin

increases expression

EXP

Methapyrilene results in increased expression of PTTG1 mRNA

PMID:15890375 PMID:22484513 PMID:22584684

NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309

G

pseudouridine 5'-phosphatase

decreases methylation

ISO

Methapyrilene results in decreased methylation of PUDP intron

NCBI chr18:46,064,867...46,067,247
Ensembl chr18:46,063,292...46,067,443

G

pumilio RNA-binding family member 1

decreases expression

EXP

Methapyrilene results in decreased expression of PUM1 mRNA

NCBI chr 5:148,120,712...148,238,468
Ensembl chr 5:148,121,254...148,238,466

G

purine rich element binding protein A

decreases expression

EXP

Methapyrilene results in decreased expression of PURA mRNA

NCBI chr18:28,159,103...28,179,539
Ensembl chr18:28,125,126...28,211,111

G

pseudouridine synthase 1

increases methylation

ISO

Methapyrilene results in increased methylation of PUS1 intron

NCBI chr12:51,539,659...51,548,975
Ensembl chr12:51,540,212...51,548,973

G

PVR cell adhesion molecule

increases expression

EXP

Methapyrilene results in increased expression of PVR mRNA

PMID:16393664 PMID:30467583

NCBI chr 1:88,689,235...88,704,641
Ensembl chr 1:88,688,981...88,704,630

G

Pvt1 oncogene

increases methylation

ISO

Methapyrilene results in increased methylation of PVT1 intron

NCBI chr 7:95,545,916...95,769,306

G

PX domain containing serine/threonine kinase like

decreases expression

EXP

Methapyrilene results in decreased expression of PXK mRNA

NCBI chr15:19,190,085...19,258,711
Ensembl chr15:19,190,085...19,258,671

G

peroxisomal membrane protein 4

decreases expression

EXP

Methapyrilene results in decreased expression of PXMP4 mRNA

NCBI chr 3:163,553,582...163,570,829
Ensembl chr 3:163,553,599...163,570,829

G

glycogen phosphorylase B

decreases methylation

ISO

Methapyrilene results in decreased methylation of PYGB polyA tail

NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961

G

peptide YY

increases methylation

ISO

Methapyrilene results in increased methylation of PYY intron

NCBI chr10:87,561,347...87,562,470
Ensembl chr10:87,561,353...87,562,206

G

glutaminyl-tRNA synthetase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of QARS1 promoter

NCBI chr 8:118,086,243...118,094,274
Ensembl chr 8:118,086,228...118,094,274

G

quinoid dihydropteridine reductase

decreases expression

EXP

Methapyrilene results in decreased expression of QDPR mRNA

NCBI chr14:69,882,776...69,896,378
Ensembl chr14:69,882,612...69,896,379

G

pyroglutamylated RFamide peptide receptor like

increases methylation

EXP

Methapyrilene results in increased methylation of QRFPRL gene

NCBI chr 4:96,008,134...96,086,800
Ensembl chr 4:96,008,134...96,086,800

G

glutamine rich 2

affects methylation

ISO

Methapyrilene affects the methylation of QRICH2 intron

NCBI chr10:102,168,103...102,196,497
Ensembl chr10:102,167,124...102,196,497

G

R3H domain and coiled-coil containing 1-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of R3HCC1L intron

NCBI chr 1:251,266,438...251,344,495
Ensembl chr 1:251,266,493...251,344,495

G

R3H domain containing 2

increases expression
decreases methylation

EXP
ISO

Methapyrilene results in increased expression of R3HDM2 mRNA
Methapyrilene results in decreased methylation of R3HDM2 exon

PMID:22484513 PMID:30157460

NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862

G

RAB11 family interacting protein 4

affects methylation

ISO

Methapyrilene affects the methylation of RAB11FIP4 intron

NCBI chr10:65,048,070...65,156,086
Ensembl chr10:65,048,140...65,152,722

G

RAB20, member RAS oncogene family

increases expression

EXP

Methapyrilene results in increased expression of RAB20 mRNA

NCBI chr16:84,721,427...84,745,610
Ensembl chr16:84,721,427...84,745,610

G

RAB30, member RAS oncogene family

increases expression

EXP

Methapyrilene results in increased expression of RAB30 mRNA

NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:156,216,137...156,310,778

G

RAB35, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB35 intron

NCBI chr12:46,627,302...46,642,815
Ensembl chr12:46,627,864...46,645,426

G

RAB36, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB36 intron

NCBI chr20:13,606,086...13,624,208
Ensembl chr20:13,606,105...13,623,604

G

RAB37, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB37 intron

NCBI chr10:100,833,240...100,900,950
Ensembl chr10:100,833,397...100,900,944

G

RAB3C, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB3C 3' UTR

NCBI chr 2:43,353,822...43,577,226
Ensembl chr 2:43,361,093...43,577,022

G

RAB3D, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB3D intron

NCBI chr 8:28,714,706...28,725,379
Ensembl chr 8:28,716,241...28,725,317

G

Rab40b, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB40B intron

NCBI chr10:107,129,801...107,157,375
Ensembl chr10:107,129,801...107,157,457

G

RAB5B, member RAS oncogene family

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAB5B intron

NCBI chr 7:1,693,971...1,712,936
Ensembl chr 7:1,693,989...1,712,780

G

RAB6A, member RAS oncogene family

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of RAB6A intron
Methapyrilene results in decreased expression of RAB6A mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:164,370,033...164,422,324
Ensembl chr 1:164,369,861...164,417,763

G

RAB8A, member RAS oncogene family

increases methylation

ISO

Methapyrilene results in increased methylation of RAB8A intron

NCBI chr16:17,688,049...17,709,412
Ensembl chr16:17,688,050...17,709,477

G

rabaptin, RAB GTPase binding effector protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of RABEP1 intron

NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177

G

RAD17 checkpoint clamp loader component

decreases expression

EXP

Methapyrilene results in decreased expression of RAD17 mRNA

NCBI chr 2:33,498,335...33,528,614
Ensembl chr 2:33,498,336...33,528,144

G

RAD21 cohesin complex component

decreases expression

EXP

Methapyrilene results in decreased expression of RAD21 mRNA

NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657

G

RAD51 recombinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAD51 intron

NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469

G

RAD51 paralog B

increases methylation

ISO

Methapyrilene results in increased methylation of RAD51B intron

NCBI chr 6:103,829,390...104,373,923
Ensembl chr 6:103,829,554...104,374,509

G

RAD54 like

increases methylation

ISO

Methapyrilene results in increased methylation of RAD54L exon

NCBI chr 5:134,812,158...134,841,821
Ensembl chr 5:134,811,532...134,841,425

G

RAD9 checkpoint clamp component A

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAD9A polyA tail

NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161

G

Rap associating with DIL domain

increases methylation

ISO

Methapyrilene results in increased methylation of RADIL intron

NCBI chr12:17,137,872...17,202,021
Ensembl chr12:17,134,935...17,202,021

G

Raf-1 proto-oncogene, serine/threonine kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAF1 intron

NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813

G

ralA binding protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of RALBP1 mRNA

NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:112,903,302...112,939,659

G

Ral GTPase activating protein catalytic subunit alpha 1

decreases expression

EXP

Methapyrilene results in decreased expression of RALGAPA1 mRNA

NCBI chr 6:78,712,554...78,987,486
Ensembl chr 6:78,701,832...78,987,486

G

Ral GTPase activating protein catalytic subunit alpha 2

increases methylation

ISO

Methapyrilene results in increased methylation of RALGAPA2 intron

NCBI chr 3:154,112,005...154,392,070
Ensembl chr 3:154,112,014...154,392,138

G

ral guanine nucleotide dissociation stimulator

decreases methylation

ISO

Methapyrilene results in decreased methylation of RALGDS intron

NCBI chr 3:32,237,644...32,278,045
Ensembl chr 3:32,237,786...32,278,045

G

ral guanine nucleotide dissociation stimulator like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RGL1 intron

NCBI chr13:67,184,402...67,454,019
Ensembl chr13:67,184,402...67,454,019

G

ral guanine nucleotide dissociation stimulator like 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of RGL3 polyA tail

NCBI chr 8:28,775,187...28,796,765
Ensembl chr 8:28,776,909...28,796,771

G

RALY heterogeneous nuclear ribonucleoprotein

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of RALY mRNA
Methapyrilene results in increased methylation of RALY intron

PMID:30157460 PMID:30467583

NCBI chr 3:163,766,183...163,830,726
Ensembl chr 3:163,766,478...163,830,740

G

receptor activity modifying protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of RAMP1 intron

NCBI chr 9:99,213,031...99,263,696

G

RAN binding protein 17

increases methylation

ISO

Methapyrilene results in increased methylation of RANBP17 intron

NCBI chr10:18,304,634...18,607,162
Ensembl chr10:18,305,227...18,607,047

G

RAN binding protein 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of RANBP3 exon

NCBI chr 9:1,594,344...1,631,587
Ensembl chr 9:1,594,346...1,631,587

G

RAN binding protein 6

decreases expression

EXP

Methapyrilene results in decreased expression of RANBP6 mRNA

NCBI chr 1:236,985,930...236,990,451
Ensembl chr 1:236,985,602...236,990,576

G

Rap1 GTPase-activating protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAP1GAP exon

NCBI chr 5:155,157,511...155,222,622
Ensembl chr 5:155,157,558...155,222,622

G

RAP1 GTPase activating protein 2

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of RAP1GAP2 exon
Methapyrilene results in decreased methylation of RAP1GAP2 intron

NCBI chr10:59,753,822...59,970,946
Ensembl chr10:59,753,822...59,970,887

G

Rap guanine nucleotide exchange factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAPGEF1 intron

NCBI chr 3:33,296,211...33,414,119
Ensembl chr 3:33,296,230...33,414,119

G

Rap guanine nucleotide exchange factor 4

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of RAPGEF4 intron
Methapyrilene results in decreased expression of RAPGEF4 mRNA

PMID:30157460 PMID:30467583

NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:77,217,039...77,509,978

G

Rap guanine nucleotide exchange factor 5

increases methylation

ISO

Methapyrilene results in increased methylation of RAPGEF5 intron

NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:144,580,976...144,822,908

G

Rap guanine nucleotide exchange factor 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of RAPGEF6 intron

NCBI chr10:39,156,573...39,324,947
Ensembl chr10:39,156,620...39,324,946

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

decreases expression

EXP

Methapyrilene results in decreased expression of RAPH1 mRNA

NCBI chr 9:69,397,272...69,484,174
Ensembl chr 9:69,401,517...69,484,019

G

retinoic acid receptor, beta

decreases methylation

ISO

Methapyrilene results in decreased methylation of RARB intron

NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040

G

retinoic acid receptor responder 2

increases expression

EXP

Methapyrilene results in increased expression of RARRES2 mRNA

NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457

G

RAS p21 protein activator 3

increases methylation

ISO

Methapyrilene results in increased methylation of RASA3 intron

NCBI chr16:82,557,556...82,671,527
Ensembl chr16:82,557,428...82,672,984

G

RAS protein activator like 1

increases methylation

ISO

Methapyrilene results in increased methylation of RASAL1 intron

NCBI chr12:41,541,865...41,574,957
Ensembl chr12:41,541,865...41,574,315

G

ras related dexamethasone induced 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RASD1 3' UTR

NCBI chr10:45,265,975...45,275,279
Ensembl chr10:45,265,979...45,267,710

G

RAS and EF hand domain containing

affects methylation

ISO

Methapyrilene affects the methylation of RASEF intron

NCBI chr 5:92,595,148...92,665,526
Ensembl chr 5:92,595,148...92,666,117

G

RasGEF domain family, member 1A

increases methylation

ISO

Methapyrilene results in increased methylation of RASGEF1A intron

NCBI chr 4:152,859,900...152,940,365
Ensembl chr 4:152,914,578...152,940,365

G

RAS protein-specific guanine nucleotide-releasing factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RASGRF1 intron

NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:99,324,749...99,454,089

G

RAS protein-specific guanine nucleotide-releasing factor 2

increases methylation

ISO

Methapyrilene results in increased methylation of RASGRF2 intron

NCBI chr 2:24,848,699...25,096,773
Ensembl chr 2:24,848,699...25,147,558

G

Ras association domain family member 1

increases expression

EXP

Methapyrilene results in increased expression of RASSF1 mRNA

NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805

G

Ras association domain family member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of RASSF2 intron

NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:139,697,187...139,733,368

G

Ras association domain family member 4

increases methylation

ISO

Methapyrilene results in increased methylation of RASSF4 intron

NCBI chr 4:151,569,984...151,605,203
Ensembl chr 4:151,569,984...151,604,883

G

RB transcriptional corepressor 1

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of RB1 mRNA
Methapyrilene results in decreased methylation of RB1 intron

PMID:15890375 PMID:30157460

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

RB binding protein 9, serine hydrolase

decreases expression

EXP

Methapyrilene results in decreased expression of RBBP9 mRNA

NCBI chr 3:152,378,426...152,392,370
Ensembl chr 3:152,378,699...152,385,489

G

ribosome binding factor A

increases methylation

ISO

Methapyrilene results in increased methylation of RBFA intron

NCBI chr18:75,914,247...75,923,893
Ensembl chr18:75,914,145...75,939,219

G

RNA binding fox-1 homolog 3

increases methylation

ISO

Methapyrilene results in increased methylation of RBFOX3 intron

NCBI chr10:104,218,940...104,655,863
Ensembl chr10:104,218,940...104,551,945

G

RB transcriptional corepressor like 2

decreases expression

EXP

Methapyrilene results in decreased expression of RBL2 mRNA

PMID:26558467 PMID:30467583

NCBI chr19:32,049,690...32,096,467
Ensembl chr19:32,049,691...32,096,411

G

RNA binding motif protein 10

increases methylation

ISO

Methapyrilene results in increased methylation of RBM10 intron

NCBI chr X:4,093,914...4,126,060
Ensembl chr X:4,093,914...4,126,060

G

RNA binding motif protein 19

decreases methylation

ISO

Methapyrilene results in decreased methylation of RBM19 intron

NCBI chr12:42,026,277...42,111,530
Ensembl chr12:42,026,278...42,111,530

G

RNA binding motif protein 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of RBM20 exon

NCBI chr 1:262,671,311...262,912,551
Ensembl chr 1:262,688,978...262,891,364

G

RNA binding motif protein 38

increases expression

EXP

Methapyrilene results in increased expression of RBM38 mRNA

NCBI chr 3:182,219,898...182,232,723
Ensembl chr 3:182,219,899...182,232,714

G

RNA binding motif protein 4

increases methylation

ISO

Methapyrilene results in increased methylation of RBM4 promoter

NCBI chr 1:211,507,845...211,516,907
Ensembl chr 1:211,506,343...211,516,891

G

RNA binding motif protein 47

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of RBM47 intron
Methapyrilene results in decreased expression of RBM47 mRNA

PMID:30157460 PMID:30467583

NCBI chr14:42,407,226...42,545,304
Ensembl chr14:42,466,335...42,543,163

G

RNA binding motif, single stranded interacting protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of RBMS1 mRNA

NCBI chr 3:65,604,475...65,829,072
Ensembl chr 3:65,606,358...65,829,013

G

recombination signal binding protein for immunoglobulin kappa J region-like 2

decreases expression

EXP

Methapyrilene results in decreased expression of RBPJL2 mRNA

NCBI chr 5:10,248,069...10,249,467

G

RNA binding protein, mRNA processing factor 2

affects methylation

ISO

Methapyrilene affects the methylation of RBPMS2 intron

NCBI chr 8:75,048,159...75,079,393
Ensembl chr 8:75,048,263...75,079,396

G

regulator of calcineurin 1

increases expression

EXP

Methapyrilene results in increased expression of RCAN1 mRNA

NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236

G

regulator of calcineurin 2

increases methylation

ISO

Methapyrilene results in increased methylation of RCAN2 intron

NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:24,456,861...24,672,189

G

RCC1 and BTB domain containing protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of RCBTB1 mRNA

NCBI chr15:37,430,453...37,477,920
Ensembl chr15:37,435,070...37,480,803

G

regulator of chromosome condensation 1

increases methylation

ISO

Methapyrilene results in increased methylation of RCC1 intron

NCBI chr 5:149,810,037...149,828,475
Ensembl chr 5:149,810,689...149,828,523

G

RNA terminal phosphate cyclase-like 1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of RCL1 intron
Methapyrilene results in decreased expression of RCL1 mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:236,238,078...236,282,597
Ensembl chr 1:236,238,031...236,315,894

G

reticulocalbin 1

decreases expression

EXP

Methapyrilene results in decreased expression of RCN1 mRNA

NCBI chr 3:112,295,838...112,310,082
Ensembl chr 3:112,295,838...112,310,082

G

reticulocalbin 2

increases expression

EXP

Methapyrilene results in increased expression of RCN2 mRNA

NCBI chr 8:65,345,247...65,362,290
Ensembl chr 8:65,345,273...65,364,632

G

reticulocalbin 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of RCN3 intron

NCBI chr 1:104,700,969...104,710,228
Ensembl chr 1:104,700,545...104,710,249

G

RD3 regulator of GUCY2D

increases methylation

ISO

Methapyrilene results in increased methylation of RD3 intron

NCBI chr13:106,060,657...106,097,063
Ensembl chr13:106,084,171...106,093,540

G

retinol dehydrogenase 13

decreases methylation

ISO

Methapyrilene results in decreased methylation of RDH13 intron

NCBI chr 1:78,415,765...78,444,116
Ensembl chr 1:78,415,782...78,490,102

G

retinol dehydrogenase 14

decreases expression

EXP

Methapyrilene results in decreased expression of RDH14 mRNA

NCBI chr 6:38,875,693...38,880,836
Ensembl chr 6:38,875,693...38,880,836

G

retinol dehydrogenase 7

decreases expression

EXP

Methapyrilene results in decreased expression of RDH7 mRNA

NCBI chr 7:65,561,259...65,574,618
Ensembl chr 7:65,560,822...65,574,635

G

radixin

decreases expression

EXP

Methapyrilene results in decreased expression of RDX mRNA

NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:61,274,460...61,333,967

G

RecQ like helicase 5

decreases methylation

ISO

Methapyrilene results in decreased methylation of RECQL5 intron

NCBI chr10:101,625,477...101,664,582
Ensembl chr10:101,625,480...101,664,663

G

receptor accessory protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of REEP1 intron

NCBI chr 4:105,303,974...105,420,611
Ensembl chr 4:105,303,969...105,420,602

G

receptor accessory protein 4

affects methylation

ISO

Methapyrilene affects the methylation of REEP4 3' UTR

NCBI chr15:52,030,022...52,033,229
Ensembl chr15:52,029,646...52,033,231

G

RELT-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of RELL1 mRNA

NCBI chr14:44,672,121...44,732,081
Ensembl chr14:44,672,224...44,732,088

G

reelin

increases methylation

ISO

Methapyrilene results in increased methylation of RELN intron

NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162

G

renin binding protein

increases methylation

ISO

Methapyrilene results in increased methylation of RENBP intron

NCBI chr X:156,812,785...156,821,860
Ensembl chr X:156,812,411...156,821,838

G

arginine-glutamic acid dipeptide repeats

increases expression

EXP

Methapyrilene results in increased expression of RERE mRNA

NCBI chr 5:166,048,770...166,380,559
Ensembl chr 5:166,048,844...166,380,558

G

ret proto-oncogene

increases methylation

ISO

Methapyrilene results in increased methylation of RET intron

NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556

G

reticulophagy regulator 1

decreases expression

EXP

Methapyrilene results in decreased expression of FAM134B mRNA

NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:78,066,031...78,225,356

G

RNA exonuclease 1 homolog

increases methylation

EXP
ISO

Methapyrilene results in increased methylation of REXO1 gene
Methapyrilene results in increased methylation of REXO1 polyA tail

PMID:26431795 PMID:30157460

NCBI chr 7:9,804,740...9,824,717
Ensembl chr 7:9,804,754...9,824,712

G

refilin A

affects methylation

ISO

Methapyrilene affects the methylation of ZNF664-RFLNA intron

NCBI chr12:37,294,643...37,323,373
Ensembl chr12:37,294,643...37,303,535

G

RFT1 homolog

decreases expression

EXP

Methapyrilene results in decreased expression of RFT1 mRNA

NCBI chr16:5,833,521...5,867,578
Ensembl chr16:5,833,546...5,880,165

G

raftlin lipid raft linker 1

increases methylation

ISO

Methapyrilene results in increased methylation of RFTN1 intron

NCBI chr 9:18,302,143...18,499,819
Ensembl chr 9:18,285,934...18,499,819

G

ring finger and WD repeat domain 3

increases methylation

ISO

Methapyrilene results in increased methylation of RFWD3 intron

NCBI chr19:56,145,221...56,177,871
Ensembl chr19:56,145,221...56,177,815

G

regulatory factor X2

affects methylation

ISO

Methapyrilene affects the methylation of RFX2 intron

NCBI chr 9:1,691,762...1,759,159
Ensembl chr 9:1,690,612...1,758,529

G

regulatory factor X8

increases methylation

ISO

Methapyrilene results in increased methylation of RFX8 intron

NCBI chr 9:49,453,282...49,517,123
Ensembl chr 9:49,453,289...49,515,134

G

regucalcin

increases expression

EXP

Methapyrilene results in increased expression of RGN protein

NCBI chr X:4,172,537...4,190,112
Ensembl chr X:4,172,537...4,190,251

G

regulator of G-protein signaling 12

affects methylation

ISO

Methapyrilene affects the methylation of RGS12 intron

NCBI chr14:79,940,561...80,048,637
Ensembl chr14:79,940,565...80,034,859

G

regulator of G-protein signaling 2

increases expression

EXP

Methapyrilene results in increased expression of RGS2 mRNA

NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697

G

regulator of G-protein signaling 6

increases methylation

ISO

Methapyrilene results in increased methylation of RGS6 intron

NCBI chr 6:107,875,883...108,527,472
Ensembl chr 6:107,876,039...108,555,840

G

regulator of G-protein signaling 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of RGS7 intron

NCBI chr13:89,511,492...89,941,082
Ensembl chr13:89,511,150...89,940,987

G

regulator of G-protein signaling 9

decreases methylation

ISO

Methapyrilene results in decreased methylation of RGS9 polyA tail

NCBI chr10:94,696,556...94,770,387
Ensembl chr10:94,696,556...94,770,387

G

rhomboid 5 homolog 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of RHBDF2 intron

NCBI chr10:102,331,991...102,359,117
Ensembl chr10:102,331,991...102,359,117

G

rhomboid like 2

increases methylation

ISO

Methapyrilene results in increased methylation of RHBDL2 intron

NCBI chr 5:141,322,246...141,376,702
Ensembl chr 5:141,322,354...141,366,747

G

rhomboid like 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of RHBDL3 intron

NCBI chr10:65,797,145...65,851,949
Ensembl chr10:65,797,209...65,851,937

G

Rh family B glycoprotein

increases expression

EXP

Methapyrilene results in increased expression of RHBG mRNA

NCBI chr 2:176,002,886...176,015,201
Ensembl chr 2:176,002,887...176,015,609

G

Rh family, C glycoprotein

increases methylation

ISO

Methapyrilene results in increased methylation of RHCG intron

NCBI chr 1:142,941,046...142,965,242
Ensembl chr 1:142,941,048...142,965,376

G

Ras homolog, mTORC1 binding

increases expression
increases methylation

EXP
ISO

Methapyrilene results in increased expression of RHEB mRNA
Methapyrilene results in increased methylation of RHEB intron

PMID:15890375 PMID:30157460

NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:11,012,643...11,053,931

G

rhodopsin

decreases methylation

ISO

Methapyrilene results in decreased methylation of RHO exon

NCBI chr 4:150,653,205...150,658,367
Ensembl chr 4:150,653,205...150,658,367

G

ras homolog family member B

increases expression

EXP

Methapyrilene results in increased expression of RHOB mRNA

NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772

G

Rho-related BTB domain containing 3

decreases expression

EXP

Methapyrilene results in decreased expression of RHOBTB3 mRNA

NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906

G

RIC8 guanine nucleotide exchange factor B

decreases methylation

ISO

Methapyrilene results in decreased methylation of RIC8B promoter

NCBI chr 7:20,636,337...20,730,066
Ensembl chr 7:20,636,687...20,730,178

G

reactive intermediate imine deaminase A homolog

increases expression

EXP

Methapyrilene results in increased expression of RIDA mRNA

NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692

G

RNA sensor RIG-1

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of RIGI intron
Methapyrilene results in decreased expression of RIGI mRNA

PMID:30157460 PMID:30467583

NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995

G

ribosomal modification protein rimK-like family member B

decreases methylation

ISO

Methapyrilene results in decreased methylation of RIMKLB intron; Methapyrilene results in decreased methylation of RIMKLB promoter

NCBI chr 4:157,336,950...157,396,970
Ensembl chr 4:157,344,414...157,378,727

G

regulating synaptic membrane exocytosis 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of RIMS2 intron

NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:72,133,170...72,645,499

G

regulating synaptic membrane exocytosis 3

increases methylation

ISO

Methapyrilene results in increased methylation of RIMS3 intron

NCBI chr 5:139,714,302...139,754,145
Ensembl chr 5:139,714,320...139,754,145

G

Ras and Rab interactor 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of RIN2 intron

NCBI chr 3:153,540,147...153,756,897
Ensembl chr 3:153,540,214...153,756,897

G

receptor interacting serine/threonine kinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of RIPK1 mRNA

NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167

G

receptor-interacting serine-threonine kinase 3

increases expression

EXP

Methapyrilene results in increased expression of RIPK3 mRNA

NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025

G

RHO family interacting cell polarization regulator 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of FAM65A exon

NCBI chr19:50,387,447...50,416,323
Ensembl chr19:50,387,523...50,416,319

G

required for meiotic nuclear division 1 homolog

decreases expression

EXP

Methapyrilene results in decreased expression of RMND1 mRNA

NCBI chr 1:43,265,207...43,299,748
Ensembl chr 1:43,265,207...43,299,682

G

ribonuclease A family member 4

decreases expression

EXP

Methapyrilene results in decreased expression of RNASE4 mRNA

NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639

G

Rho family GTPase 1

increases expression

EXP

Methapyrilene results in increased expression of RND1 mRNA

PMID:23558518 PMID:30467583

NCBI chr 7:131,700,321...131,707,392
Ensembl chr 7:131,700,321...131,707,392

G

Rho family GTPase 3

increases expression

EXP

Methapyrilene results in increased expression of RND3 mRNA

NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:55,980,355...55,998,536

G

ring finger protein 113A2

decreases expression

EXP

Methapyrilene results in decreased expression of RNF113A2 mRNA

NCBI chr 6:109,794,794...109,796,075
Ensembl chr 6:109,794,684...109,796,273

G

ring finger protein 123

increases methylation

ISO

Methapyrilene results in increased methylation of RNF123 intron

NCBI chr 8:117,618,776...117,646,400
Ensembl chr 8:117,618,425...117,646,274

G

ring finger protein 125

decreases expression

EXP

Methapyrilene results in decreased expression of RNF125 mRNA

NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,528,838...12,554,430

G

ring finger protein 138

increases expression

EXP

Methapyrilene results in increased expression of RNF138 mRNA

NCBI chr18:12,558,430...12,590,849
Ensembl chr18:12,566,502...12,590,848

G

ring finger protein 19A, RBR E3 ubiquitin protein ligase

increases methylation

ISO

Methapyrilene results in increased methylation of RNF19A intron

NCBI chr 7:69,310,947...69,350,567
Ensembl chr 7:69,310,947...69,350,225

G

ring finger protein 212B

decreases methylation

ISO

Methapyrilene results in decreased methylation of RNF212B intron

NCBI chr15:32,244,620...32,292,358
Ensembl chr15:32,244,558...32,292,021

G

ring finger protein 213

increases methylation

ISO

Methapyrilene results in increased methylation of RNF213 intron

NCBI chr10:105,154,873...105,254,148
Ensembl chr10:105,157,904...105,254,148

G

ring finger protein 220

decreases methylation

ISO

Methapyrilene results in decreased methylation of RNF220 intron

NCBI chr 5:135,975,739...136,198,017
Ensembl chr 5:135,975,739...136,197,858

G

ring finger protein 24

increases methylation

ISO

Methapyrilene results in increased methylation of RNF24 intron

NCBI chr 3:138,973,492...138,987,354
Ensembl chr 3:138,973,492...139,028,177

G

ring finger protein 43

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of RNF43 intron
Methapyrilene results in decreased methylation of RNF43 exon

NCBI chr10:72,958,744...73,034,540
Ensembl chr10:72,961,641...73,034,551

G

ring finger protein 6

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of RNF6 intron
Methapyrilene results in decreased expression of RNF6 mRNA

PMID:30157460 PMID:30467583

NCBI chr12:13,929,160...13,940,663
Ensembl chr12:13,931,074...13,940,652

G

ring finger protein 8

decreases expression

EXP

Methapyrilene results in decreased expression of RNF8 mRNA

NCBI chr20:7,683,890...7,708,437

G

ring finger protein, transmembrane 2

increases methylation

ISO

Methapyrilene results in increased methylation of RNFT2 intron

NCBI chr12:43,990,113...44,048,215
Ensembl chr12:43,990,304...44,048,213

G

RNA guanylyltransferase and 5'-phosphatase

decreases methylation

ISO

Methapyrilene results in decreased methylation of RNGTT intron

NCBI chr 5:52,503,335...52,709,604
Ensembl chr 5:52,503,313...52,709,597

G

RNA, U5F small nuclear 1 like 1

increases methylation

ISO

Methapyrilene results in increased methylation of RNU5F-1 intron

NCBI chr 5:135,903,593...135,903,708
Ensembl chr 5:135,903,593...135,903,708

G

roundabout guidance receptor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of ROBO1 intron

NCBI chr11:24,067,869...25,108,694
Ensembl chr11:24,067,878...25,108,694

G

roundabout guidance receptor 2

affects methylation

ISO

Methapyrilene affects the methylation of ROBO2 intron

NCBI chr11:26,015,919...27,583,750
Ensembl chr11:26,015,919...26,876,185

G

receptor tyrosine kinase-like orphan receptor 2

increases methylation

ISO

Methapyrilene results in increased methylation of ROR2 intron

NCBI chr17:12,124,749...12,300,044
Ensembl chr17:12,124,749...12,300,044

G

RAR-related orphan receptor A

affects methylation

ISO

Methapyrilene affects the methylation of RORA intron

NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730

G

RAR-related orphan receptor B

increases methylation

ISO

Methapyrilene results in increased methylation of RORB intron

NCBI chr 1:225,790,216...225,970,973
Ensembl chr 1:225,790,216...225,970,973

G

ROS proto-oncogene 1 , receptor tyrosine kinase

decreases methylation

ISO

Methapyrilene results in decreased methylation of ROS1 intron

NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,975,329...32,126,547

G

ribosomal protein L10

increases expression

EXP

Methapyrilene results in increased expression of RPL10 mRNA

NCBI chr X:157,205,850...157,208,057
Ensembl chr X:157,205,836...157,208,049

G

ribosomal protein L10A

increases expression

EXP

Methapyrilene results in increased expression of RPL10A mRNA

NCBI chr20:6,390,533...6,393,091
Ensembl chr20:6,390,179...6,393,091

G

ribosomal protein L13

increases expression

EXP

Methapyrilene results in increased expression of RPL13 mRNA

NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059

G

ribosomal protein L13A

decreases methylation

ISO

Methapyrilene results in decreased methylation of RPL13A promoter

NCBI chr 1:104,746,223...104,748,975
Ensembl chr 1:104,746,223...104,748,914

G

ribosomal protein L15

increases expression

EXP

Methapyrilene results in increased expression of RPL15 mRNA

NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308

G

ribosomal protein L17

increases expression

EXP

Methapyrilene results in increased expression of RPL17 mRNA

NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638
Ensembl chr18:111,722,010...111,722,638

G

ribosomal protein L23

increases expression

EXP

Methapyrilene results in increased expression of RPL23 mRNA

NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214

G

ribosomal protein L26 like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RPL26L1 promoter

NCBI chr10:17,024,807...17,029,028

G

ribosomal protein L39 like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RPL39L intron

NCBI chr10:5,962,506...5,966,621
Ensembl chr10:5,962,515...5,966,621

G

ribosomal protein L6

increases expression

EXP

Methapyrilene results in increased expression of RPL6 mRNA

NCBI chr12:41,008,142...41,012,756
Ensembl chr12:41,008,142...41,025,733

G

ribosomal protein L7

increases expression

EXP

Methapyrilene results in increased expression of RPL7 mRNA

NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451

G

ribosomal protein L7A

increases expression

EXP

Methapyrilene results in increased expression of RPL7A mRNA

NCBI chr 3:30,637,136...30,639,778
Ensembl chr 3:30,637,059...30,639,791
Ensembl chr18:30,637,059...30,639,791

G

ribosomal protein L8

increases expression

EXP

Methapyrilene results in increased expression of RPL8 mRNA

NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:110,506,800...110,509,103
Ensembl chr 3:110,506,800...110,509,103

G

ribosomal protein lateral stalk subunit P1

increases expression

EXP

Methapyrilene results in increased expression of RPLP1 mRNA

NCBI chr 8:71,289,539...71,290,872
Ensembl chr 8:71,289,535...71,290,872

G

ribophorin I

decreases expression

EXP

Methapyrilene results in decreased expression of RPN1 mRNA

NCBI chr 4:122,100,976...122,122,382
Ensembl chr 4:122,100,813...122,122,382

G

ribonuclease P/MRP subunit p21

increases expression

EXP

Methapyrilene results in increased expression of RPP21 mRNA

NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,023,186...2,025,308

G

ribonuclease P/MRP subunit p25 like

decreases methylation

ISO

Methapyrilene results in decreased methylation of RPP25L polyA tail

NCBI chr 5:61,674,299...61,675,844
Ensembl chr 5:61,672,199...61,675,168

G

reprimo, TP53 dependent G2 arrest mediator homolog

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of RPRM mRNA
Methapyrilene results in decreased expression of RPRM mRNA

PMID:22484513 PMID:30467583

NCBI chr 3:58,948,618...58,950,035
Ensembl chr 3:58,799,866...58,950,542

G

ribosomal protein S15a

increases expression

EXP

Methapyrilene results in increased expression of RPS15A mRNA

NCBI chr 1:181,854,396...181,861,330
Ensembl chr 1:181,854,396...181,861,201

G

ribosomal protein S17

increases expression

EXP

Methapyrilene results in increased expression of RPS17 mRNA

NCBI chr 1:144,705,150...144,707,736
Ensembl chr 1:144,705,149...144,707,734
Ensembl chr 8:144,705,149...144,707,734

G

ribosomal protein S19

increases methylation
increases expression

ISO
EXP

Methapyrilene results in increased methylation of RPS19 intron
Methapyrilene results in increased expression of RPS19 mRNA

PMID:15890375 PMID:30157460

NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132

G

ribosomal protein S24

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of RPS24 mRNA
Methapyrilene results in decreased expression of RPS24 mRNA

PMID:15890375 PMID:30467583

NCBI chr16:95,429...101,146
Ensembl chr16:96,484...101,144

G

ribosomal protein S27-like

increases expression

EXP

Methapyrilene results in increased expression of RPS27L mRNA

NCBI chr 8:76,443,658...76,448,593
Ensembl chr12:33,713,661...33,714,130
Ensembl chr 8:33,713,661...33,714,130

G

ribosomal protein S3

increases expression

EXP

Methapyrilene results in increased expression of RPS3 mRNA

NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776

G

ribosomal protein S4, X-linked

increases expression

EXP

Methapyrilene results in increased expression of RPS4X mRNA

NCBI chr X:71,338,478...71,342,921
Ensembl chr X:71,338,479...71,342,921
Ensembl chr 4:71,338,479...71,342,921

G

ribosomal protein S6 kinase A2

affects methylation

ISO

Methapyrilene affects the methylation of RPS6KA2 intron

NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338

G

ribosomal protein S7

increases expression

EXP

Methapyrilene results in increased expression of RPS7 mRNA

NCBI chr 6:50,994,581...50,999,447

G

ribosomal protein SA

increases expression

EXP

Methapyrilene results in increased expression of RPSA mRNA

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737

G

regulatory associated protein of MTOR, complex 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RPTOR intron

NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

ISO

Methapyrilene results in increased expression of RRAD mRNA

NCBI chr19:360,581...363,874
Ensembl chr19:360,973...363,871

G

Ras-related GTP binding A

decreases expression

EXP

Methapyrilene results in decreased expression of RRAGA mRNA

NCBI chr 5:106,159,335...106,160,930
Ensembl chr 5:106,158,853...106,160,504

G

ribosome binding protein 1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of RRBP1 5' UTR
Methapyrilene results in decreased expression of RRBP1 mRNA

PMID:30157460 PMID:30467583

NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255

G

ras responsive element binding protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of RREB1 exon

NCBI chr17:27,082,217...27,208,061
Ensembl chr17:27,082,227...27,208,061

G

ribosomal RNA processing 1B

increases expression
decreases methylation

EXP
ISO

Methapyrilene results in increased expression of RRP1B mRNA
Methapyrilene results in decreased methylation of RRP1B intron

PMID:22484513 PMID:30157460

NCBI chr20:10,122,825...10,148,404
Ensembl chr20:10,122,812...10,148,404

G

ribosomal RNA processing 7 homolog A

increases methylation

ISO

Methapyrilene results in increased methylation of RRP7A intron

NCBI chr 7:116,142,976...116,152,874
Ensembl chr 7:116,136,385...116,152,864

G

radial spoke head component 1

increases methylation

ISO

Methapyrilene results in increased methylation of RSPH1 exon

NCBI chr20:9,343,258...9,361,988
Ensembl chr20:9,343,261...9,361,988

G

radial spoke head 14 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of RSPH14 intron

NCBI chr20:13,626,707...13,702,817
Ensembl chr20:13,595,523...13,706,782

G

R-spondin 1

increases methylation

ISO

Methapyrilene results in increased methylation of RSPO1 intron

NCBI chr 5:142,536,162...142,557,611
Ensembl chr 5:142,536,344...142,557,776

G

RT1 class Ib, locus S3

decreases expression

EXP

Methapyrilene results in decreased expression of RT1-S3 mRNA

NCBI chr20:2,675,463...2,680,229

G

regulator of telomere elongation helicase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of RTEL1 intron

NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709

G

Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

increases methylation

ISO

Methapyrilene results in increased methylation of RTF1 intron

NCBI chr 3:127,113,171...127,172,761
Ensembl chr 3:127,113,163...127,172,761

G

rhotekin 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of RTKN2 intron

NCBI chr20:20,535,553...20,608,863
Ensembl chr20:20,535,553...20,608,899

G

reticulon 4 receptor-like 1

increases methylation

ISO

Methapyrilene results in increased methylation of RTN4RL1 intron

NCBI chr10:60,541,584...60,615,302
Ensembl chr10:60,520,760...60,615,727

G

receptor (chemosensory) transporter protein 3

decreases expression

EXP

Methapyrilene results in decreased expression of RTP3 mRNA

NCBI chr 8:119,847,947...119,853,549
Ensembl chr 8:119,848,556...119,853,095

G

receptor (chemosensory) transporter protein 4

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of RTP4 mRNA
Methapyrilene results in increased methylation of RTP4 gene

PMID:30467583 PMID:31555880

NCBI chr11:90,741,992...90,840,061
Ensembl chr11:90,741,992...90,753,851

G

RUN domain containing 3A

increases methylation

ISO

Methapyrilene results in increased methylation of RUNDC3A intron

NCBI chr10:87,852,746...87,861,903
Ensembl chr10:87,852,782...87,861,901

G

RUNX family transcription factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of RUNX1 intron

NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925

G

RUNX family transcription factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of RUNX3 intron

NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835

G

urinary protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of RUP2 mRNA

NCBI chr 8:43,547,875...43,551,456
Ensembl chr 8:43,549,809...43,700,211

G

retinoid X receptor alpha

decreases expression

EXP

Methapyrilene results in decreased expression of RXRA mRNA

PMID:17450226 PMID:30467583

NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417

G

retinoid X receptor gamma

decreases expression

EXP

Methapyrilene results in decreased expression of RXRG mRNA

NCBI chr13:82,276,330...82,318,097
Ensembl chr13:82,276,291...82,318,095

G

RING1 and YY1 binding protein

increases expression

EXP

Methapyrilene results in increased expression of RYBP mRNA

NCBI chr 4:134,432,663...134,484,732
Ensembl chr 4:134,432,663...134,484,930

G

ryanodine receptor 1

increases methylation

ISO

Methapyrilene results in increased methylation of RYR1 exon; Methapyrilene results in increased methylation of RYR1 intron

NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305

G

ryanodine receptor 2

increases methylation

ISO

Methapyrilene results in increased methylation of RYR2 intron

NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705

G

ryanodine receptor 3

increases methylation

ISO

Methapyrilene results in increased methylation of RYR3 intron

NCBI chr 3:119,886,129...120,433,465
Ensembl chr 3:119,885,878...120,433,677

G

S100 calcium binding protein A2

increases methylation

ISO

Methapyrilene results in increased methylation of S100A2 intron

NCBI chr 2:178,374,659...178,375,903

G

S100 calcium binding protein A8

decreases expression
increases expression

ISO
EXP

Methapyrilene results in decreased expression of S100A8 mRNA
Methapyrilene results in increased expression of S100A8 mRNA

NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221

G

sphingosine-1-phosphate receptor 2

increases methylation

ISO

Methapyrilene results in increased methylation of S1PR2 polyA tail

NCBI chr 8:27,779,452...27,790,344
Ensembl chr 8:27,774,566...27,790,577

G

serum amyloid A4

decreases expression

EXP

Methapyrilene results in decreased expression of SAA4 mRNA

NCBI chr 1:106,383,856...106,388,158
Ensembl chr 1:106,383,856...106,387,354

G

SAC1 like phosphatidylinositide phosphatase

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of SACM1L mRNA
Methapyrilene results in increased methylation of SACM1L promoter

PMID:30157460 PMID:30467583

NCBI chr 8:132,053,465...132,109,857
Ensembl chr 8:132,053,049...132,109,857

G

scaffold attachment factor B

decreases methylation

ISO

Methapyrilene results in decreased methylation of SAFB intron

NCBI chr 9:1,504,657...1,525,545
Ensembl chr 9:1,504,456...1,525,781

G

spalt-like transcription factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of SALL1 mRNA

NCBI chr19:34,179,316...34,196,278
Ensembl chr19:34,181,078...34,196,278

G

sterile alpha motif domain containing 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of SAMD3 intron

NCBI chr 1:20,920,129...20,967,595
Ensembl chr 1:20,920,129...20,967,595

G

sterile alpha motif domain containing 5

increases methylation

ISO

Methapyrilene results in increased methylation of SAMD5 intron

NCBI chr 1:5,861,793...5,911,153
Ensembl chr 1:5,497,567...5,911,064

G

sterile alpha motif domain containing 8

increases methylation

ISO

Methapyrilene results in increased methylation of SAMD8 intron

NCBI chr15:2,561,435...2,611,702
Ensembl chr15:2,561,435...2,607,052

G

SAMM50 sorting and assembly machinery component

decreases methylation

ISO

Methapyrilene results in decreased methylation of SAMM50 intron

NCBI chr 7:117,197,460...117,221,668
Ensembl chr 7:117,197,381...117,224,581

G

Sin3A associated protein 130

decreases methylation

ISO

Methapyrilene results in decreased methylation of SAP130 3' UTR

NCBI chr18:23,518,773...23,619,840
Ensembl chr18:23,518,680...23,619,840

G

SAP30 binding protein

increases methylation

ISO

Methapyrilene results in increased methylation of SAP30BP intron

NCBI chr10:101,664,714...101,697,430
Ensembl chr10:101,664,697...101,697,429

G

sarcosine dehydrogenase

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of SARDH mRNA
Methapyrilene results in increased methylation of SARDH intron

PMID:30157460 PMID:30467583

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137

G

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

decreases methylation

ISO

Methapyrilene results in decreased methylation of SART1 intron

NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486

G

strawberry notch homolog 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SBNO1 intron

NCBI chr12:37,835,306...37,895,861
Ensembl chr12:37,846,514...37,891,231

G

SR-related CTD-associated factor 8

decreases expression

EXP

Methapyrilene results in decreased expression of SCAF8 mRNA

NCBI chr 1:46,132,972...46,321,162
Ensembl chr 1:46,132,873...46,261,174

G

secretory carrier membrane protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of SCAMP1 mRNA

NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742

G

scavenger receptor class A, member 5

affects methylation
decreases expression

ISO
EXP

Methapyrilene affects the methylation of SCARA5 intron
Methapyrilene results in decreased expression of SCARA5 mRNA

PMID:30157460 PMID:30467583

NCBI chr15:44,055,576...44,160,593
Ensembl chr15:44,055,630...44,160,585

G

stearoyl-CoA desaturase

decreases expression

EXP

Methapyrilene results in decreased expression of SCD1 mRNA

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

schwannomin interacting protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of SCHIP1 intron

NCBI chr 2:154,437,217...155,198,560
Ensembl chr 2:155,060,798...155,198,557

G

Scm polycomb group protein homolog 1

increases methylation

ISO

Methapyrilene results in increased methylation of SCMH1 promoter

NCBI chr 5:139,276,352...139,401,118
Ensembl chr 5:139,314,447...139,403,081

G

Scm polycomb group protein like 4

increases methylation

ISO

Methapyrilene results in increased methylation of SCML4 intron

NCBI chr20:47,929,539...48,023,419
Ensembl chr20:47,929,539...48,023,419

G

sodium voltage-gated channel alpha subunit 11

increases methylation

ISO

Methapyrilene results in increased methylation of SCN11A intron

NCBI chr 8:128,374,441...128,444,718
Ensembl chr 8:128,374,449...128,444,718

G

sodium voltage-gated channel beta subunit 4

increases methylation

ISO

Methapyrilene results in increased methylation of SCN4B polyA tail

NCBI chr 8:54,343,873...54,359,046
Ensembl chr 8:54,334,548...54,359,047

G

sodium channel epithelial 1 subunit beta

decreases methylation

ISO

Methapyrilene results in decreased methylation of SCNN1B exon

NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:185,854,733...185,916,049

G

short coiled-coil protein

decreases expression

EXP

Methapyrilene results in decreased expression of SCOC mRNA

NCBI chr19:41,564,166...41,593,932
Ensembl chr19:41,564,112...41,597,912

G

sterol carrier protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of SCP2 intron

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043

G

signal peptide, CUB domain and EGF like domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of SCUBE1 exon; Methapyrilene results in increased methylation of SCUBE1 intron; Methapyrilene results in increased methylation of SCUBE1 polyA tail

NCBI chr 7:116,639,027...116,760,986
Ensembl chr 7:116,642,231...116,760,944

G

syndecan 1

increases expression

EXP

Methapyrilene results in increased expression of SDC1 mRNA

NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500

G

syndecan 2

decreases expression

EXP

Methapyrilene results in decreased expression of SDC2 mRNA

NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294

G

syndecan binding protein 2

increases expression

EXP

Methapyrilene results in increased expression of SDCBP2 mRNA

NCBI chr 3:160,521,309...160,558,452
Ensembl chr 3:160,530,927...160,558,446

G

succinate dehydrogenase complex flavoprotein subunit A

increases methylation

ISO

Methapyrilene results in increased methylation of SDHA intron

NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:30,764,590...30,790,121

G

succinate dehydrogenase complex assembly factor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SDHAF1 polyA tail

NCBI chr 1:94,703,662...94,704,611
Ensembl chr 1:94,702,409...94,706,092

G

sidekick cell adhesion molecule 1

affects methylation
increases methylation

ISO

Methapyrilene affects the methylation of SDK1 intron
Methapyrilene results in increased methylation of SDK1 polyA tail

NCBI chr12:17,491,430...18,477,914
Ensembl chr12:17,493,869...18,477,935

G

sidekick cell adhesion molecule 2

increases methylation

ISO

Methapyrilene results in increased methylation of SDK2 intron

NCBI chr10:99,324,047...99,601,683
Ensembl chr10:99,324,047...99,601,683

G

short chain dehydrogenase/reductase family 42E, member 1

decreases expression

EXP

Methapyrilene results in decreased expression of SDR42E1 mRNA

NCBI chr19:62,624,130...62,636,652
Ensembl chr19:62,624,150...62,636,756

G

short chain dehydrogenase/reductase family 9C, member 7

increases methylation

ISO

Methapyrilene results in increased methylation of SDR9C7 intron

NCBI chr 7:65,588,726...65,607,534
Ensembl chr 7:65,593,000...65,605,630

G

SEC16 homolog A, endoplasmic reticulum export factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of SEC16A exon

NCBI chr 3:29,627,779...29,662,925
Ensembl chr 3:29,627,779...29,662,319

G

SEC16 homolog B, endoplasmic reticulum export factor

decreases expression

EXP

Methapyrilene results in decreased expression of SEC16B mRNA

NCBI chr13:72,206,778...72,260,733
Ensembl chr13:72,206,772...72,260,729

G

Sec23 homolog A, COPII coat complex component

decreases expression

EXP

Methapyrilene results in decreased expression of SEC23A mRNA

NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:82,394,863...82,440,904

G

SEC24 homolog A, COPII coat complex component

decreases expression
affects methylation

EXP
ISO

Methapyrilene results in decreased expression of SEC24A mRNA
Methapyrilene affects the methylation of SEC24A intron

PMID:30157460 PMID:30467583

NCBI chr10:36,450,043...36,525,303
Ensembl chr10:36,450,043...36,525,303

G

SEC24 homolog B, COPII coat complex component

decreases expression

EXP

Methapyrilene results in decreased expression of SEC24B mRNA

NCBI chr 2:221,236,897...221,306,986
Ensembl chr 2:221,236,898...221,306,919

G

SEC24 homolog C, COPII coat complex component

decreases expression

EXP

Methapyrilene results in decreased expression of SEC24C mRNA

NCBI chr15:3,651,714...3,674,420
Ensembl chr15:3,651,714...3,673,675

G

SEC24 homolog D, COPII coat complex component

decreases expression

EXP

Methapyrilene results in decreased expression of SEC24D mRNA

NCBI chr 2:214,103,138...214,211,155
Ensembl chr 2:214,103,190...214,211,144

G

SEL1L adaptor subunit of SYVN1 ubiquitin ligase

decreases expression

EXP

Methapyrilene results in decreased expression of SEL1L mRNA

NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:116,466,163...116,510,578

G

selenium binding protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of SELENBP1 mRNA

NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295

G

selenoprotein W

increases expression

EXP

Methapyrilene results in increased expression of SELENOW mRNA

NCBI chr 1:85,727,631...85,732,703
Ensembl chr 1:85,727,632...85,732,703

G

selectin P ligand

decreases methylation

ISO

Methapyrilene results in decreased methylation of SELPLG intron

NCBI chr12:48,457,102...48,470,444
Ensembl chr12:48,456,932...48,473,154

G

semaphorin 3C

decreases expression

EXP

Methapyrilene results in decreased expression of SEMA3C mRNA

NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:18,538,454...18,701,740

G

semaphorin 3E

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA3E intron

NCBI chr 4:21,252,686...21,510,449
Ensembl chr 4:21,210,734...21,510,374

G

semaphorin 3F

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA3F intron

NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206

G

semaphorin 3G

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA3G 3' UTR

NCBI chr16:6,420,025...6,431,655
Ensembl chr16:6,420,012...6,432,553

G

semaphorin 4D

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA4D intron

NCBI chr17:13,582,085...13,688,889
Ensembl chr17:13,582,098...13,688,891

G

semaphorin 5A

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA5A intron

NCBI chr 2:85,020,724...85,451,938
Ensembl chr 2:85,020,724...85,451,938

G

semaphorin 5B

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA5B intron

NCBI chr11:78,607,805...78,730,724
Ensembl chr11:78,607,805...78,730,589

G

semaphorin 6D

increases methylation

ISO

Methapyrilene results in increased methylation of SEMA6D intron

NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:132,337,343...132,394,584

G

SUMO specific peptidase 5

increases methylation

ISO

Methapyrilene results in increased methylation of SENP5 intron

NCBI chr11:82,289,680...82,324,545
Ensembl chr11:82,289,648...82,324,542

G

selenophosphate synthetase 2

decreases expression

EXP

Methapyrilene results in decreased expression of SEPHS2 mRNA

NCBI chr 1:191,323,637...191,325,955
Ensembl chr 1:191,323,641...191,325,955

G

septin 10

decreases expression

EXP

Methapyrilene results in decreased expression of SEPTIN10 mRNA

NCBI chr20:27,644,862...27,737,817
Ensembl chr20:27,643,876...27,737,902

G

septin 8

increases methylation

ISO

Methapyrilene results in increased methylation of SEPTIN8 intron

NCBI chr10:38,185,454...38,214,502
Ensembl chr10:38,185,335...38,214,504

G

septin 9

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of SEPTIN9 intron
Methapyrilene results in decreased expression of SEPTIN9 mRNA

PMID:30157460 PMID:30467583

NCBI chr10:102,908,557...103,077,789
Ensembl chr10:102,908,560...103,077,788

G

serine incorporator 5

decreases expression

EXP

Methapyrilene results in decreased expression of SERINC5 mRNA

NCBI chr 2:25,581,952...25,685,403
Ensembl chr 2:25,581,951...25,685,403

G

stress-associated endoplasmic reticulum protein 1

increases expression

EXP

Methapyrilene results in increased expression of SERP1 mRNA

NCBI chr 2:144,907,204...144,911,187
Ensembl chr 2:144,907,205...144,911,187

G

serpin family A member 10

increases methylation

ISO

Methapyrilene results in increased methylation of SERPINA10 exon

NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:128,520,896...128,529,332

G

serine (or cysteine) proteinase inhibitor, clade A, member 3C

increases expression

EXP

Methapyrilene results in increased expression of SERPINA3C mRNA

NCBI chr 6:129,007,578...129,014,988
Ensembl chr 6:128,829,577...129,014,971

G

serpin family A member 3N

decreases expression

EXP

Methapyrilene results in decreased expression of SERPINA3N mRNA

NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415

G

serpin family A member 6

increases expression

EXP

Methapyrilene results in increased expression of SERPINA6 mRNA

NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:128,544,831...128,555,139

G

serpin family B member 9

increases expression

EXP

Methapyrilene results in increased expression of SERPINB9 mRNA

NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974

G

serpin family C member 1

increases methylation

ISO

Methapyrilene results in increased methylation of SERPINC1 exon

NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643

G

serpin family E member 1

increases expression

EXP

Methapyrilene results in increased expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

serpin family E member 2

increases methylation

ISO

Methapyrilene results in increased methylation of SERPINE2 promoter

NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202

G

SERTA domain containing 1

increases expression

EXP

Methapyrilene results in increased expression of SERTAD1 mRNA

NCBI chr 1:91,903,297...91,906,565
Ensembl chr 1:91,891,814...91,907,001

G

sestrin 1

decreases expression

EXP

Methapyrilene results in decreased expression of SESN1 mRNA

NCBI chr20:46,876,918...46,970,010
Ensembl chr20:46,876,895...46,970,010

G

SEC14 and spectrin domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of SESTD1 intron

NCBI chr 3:82,530,796...82,627,960
Ensembl chr 3:82,537,092...82,588,078

G

SET binding protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SETBP1 exon

NCBI chr18:74,465,616...74,827,455
Ensembl chr18:74,465,616...74,827,455

G

SET domain containing 6, protein lysine methyltransferase

decreases expression

EXP

Methapyrilene results in decreased expression of SETD6 mRNA

NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515

G

seizure related 6 homolog like

decreases methylation

ISO

Methapyrilene results in decreased methylation of SEZ6L 3' UTR

NCBI chr12:49,725,330...49,882,222
Ensembl chr12:49,725,330...49,882,222

G

Scm-like with four mbt domains 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SFMBT1 intron

NCBI chr16:5,896,686...6,016,311
Ensembl chr16:5,897,187...6,011,934

G

Scm-like with four mbt domains 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SFMBT2 intron

NCBI chr17:72,844,037...73,038,599
Ensembl chr17:72,845,708...73,032,172

G

sideroflexin 1

decreases expression

EXP

Methapyrilene results in decreased expression of SFXN1 mRNA

NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456

G

sarcoglycan, beta

decreases expression

EXP

Methapyrilene results in decreased expression of SGCB mRNA

NCBI chr14:34,917,663...34,932,661
Ensembl chr14:34,912,628...34,933,666

G

sarcoglycan zeta

affects methylation

ISO

Methapyrilene affects the methylation of SGCZ intron

NCBI chr16:60,363,718...61,444,256
Ensembl chr16:60,363,738...61,439,633

G

SAGA complex associated factor 29

decreases methylation

ISO

Methapyrilene results in decreased methylation of SGF29 exon

NCBI chr 1:190,668,803...190,702,500
Ensembl chr 1:190,669,028...190,717,906

G

serum/glucocorticoid regulated kinase 1

increases methylation

ISO

Methapyrilene results in increased methylation of SGK1 intron

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231

G

sphingosine-1-phosphate phosphatase 1

decreases expression

EXP

Methapyrilene results in decreased expression of SGPP1 mRNA

NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259

G

small G protein signaling modulator 2

increases methylation

ISO

Methapyrilene results in increased methylation of SGSM2 exon

NCBI chr10:60,216,556...60,258,199
Ensembl chr10:60,216,556...60,257,817

G

small glutamine rich tetratricopeptide repeat co-chaperone alpha

increases methylation

ISO

Methapyrilene results in increased methylation of SGTA intron

NCBI chr 7:9,304,381...9,321,157
Ensembl chr 7:9,304,197...9,321,669

G

SH2 domain containing 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of SH2D7 exon

NCBI chr 8:63,813,054...63,826,714
Ensembl chr 8:63,814,553...63,826,632

G

SH3-domain binding protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of SH3BP1 intron

NCBI chr 7:112,338,087...112,350,659
Ensembl chr 7:112,338,107...112,350,659

G

SH3-domain binding protein 4

increases methylation

ISO

Methapyrilene results in increased methylation of SH3BP4 intron

NCBI chr 9:97,107,877...97,186,878
Ensembl chr 9:97,107,877...97,186,878

G

SH3-domain binding protein 5

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of SH3BP5 intron
Methapyrilene results in decreased expression of SH3BP5 mRNA

PMID:30157460 PMID:30467583

NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,589,877...6,655,211

G

SH3 domain containing 19

decreases methylation

ISO

Methapyrilene results in decreased methylation of SH3D19 exon

NCBI chr 2:173,654,234...173,814,030
Ensembl chr 2:173,654,420...173,814,025

G

SH3 and PX domains 2A

affects methylation

ISO

Methapyrilene affects the methylation of SH3PXD2A intron

NCBI chr 1:256,094,991...256,301,120
Ensembl chr 1:256,094,991...256,300,967

G

SH3 domain containing ring finger 1

increases methylation

ISO

Methapyrilene results in increased methylation of SH3RF1 intron

NCBI chr16:33,746,396...33,912,127
Ensembl chr16:33,746,396...33,912,153

G

SH3 domain containing ring finger 3

affects methylation

ISO

Methapyrilene affects the methylation of SH3RF3 intron

NCBI chr20:27,306,937...27,642,315
Ensembl chr20:27,308,188...27,640,544

G

SH3 domain and tetratricopeptide repeats 1

increases methylation

ISO

Methapyrilene results in increased methylation of SH3TC1 intron

NCBI chr14:79,230,322...79,274,622
Ensembl chr14:79,230,371...79,274,620

G

SH3 and multiple ankyrin repeat domains 1

increases methylation

ISO

Methapyrilene results in increased methylation of SHANK1 intron

NCBI chr 1:103,944,416...103,993,887
Ensembl chr 1:103,944,813...103,992,356

G

SH3 and multiple ankyrin repeat domains 2

affects methylation

ISO

Methapyrilene affects the methylation of SHANK2 intron

NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:208,598,772...209,018,736

G

SH3 and multiple ankyrin repeat domains 3

increases methylation

ISO

Methapyrilene results in increased methylation of SHANK3 intron

NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:122,448,323...122,510,410

G

SH2 domain containing adaptor protein B

decreases methylation

ISO

Methapyrilene results in decreased methylation of SHB intron

NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:64,473,694...64,581,072

G

SHC adaptor protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SHC1 exon

NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914

G

shisa like 1

affects methylation

ISO

Methapyrilene affects the methylation of SHISAL1 intron

NCBI chr 7:117,388,210...117,491,539

G

shisa like 2B

increases methylation

ISO

Methapyrilene results in increased methylation of SHISAL2B intron

NCBI chr 2:37,736,377...37,754,126
Ensembl chr 2:37,736,387...37,753,212

G

Sh3kbp1 binding protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of SHKBP1 exon

NCBI chr 1:91,764,426...91,777,959
Ensembl chr 1:91,764,426...91,778,158

G

SNF2 histone linker PHD RING helicase

decreases expression

EXP

Methapyrilene results in decreased expression of SHPRH mRNA

NCBI chr 1:7,349,073...7,422,804
Ensembl chr 1:7,320,395...7,422,794

G

SHQ1, H/ACA ribonucleoprotein assembly factor

decreases methylation

ISO

Methapyrilene results in decreased methylation of SHQ1 intron

NCBI chr 4:134,741,190...134,861,960
Ensembl chr 4:134,769,254...134,861,945

G

shroom family member 2

increases methylation

ISO

Methapyrilene results in increased methylation of SHROOM2 intron

NCBI chr X:25,308,163...25,480,194
Ensembl chr X:25,308,163...25,479,385

G

SID1 transmembrane family, member 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SIDT1 intron

NCBI chr11:69,867,758...69,965,377
Ensembl chr11:69,868,795...69,965,519

G

sialic acid binding Ig-like lectin 10

increases methylation

ISO

Methapyrilene results in increased methylation of SIGLEC10 exon

NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:102,953,918...102,962,964

G

salt-inducible kinase 2

decreases expression

EXP

Methapyrilene results in decreased expression of SIK2 mRNA

NCBI chr 8:60,121,913...60,221,707
Ensembl chr 8:60,121,913...60,221,818

G

SIK family kinase 3

increases methylation

ISO

Methapyrilene results in increased methylation of SIK3 intron

NCBI chr 8:55,208,969...55,419,138
Ensembl chr 8:55,208,815...55,419,138

G

SIM bHLH transcription factor 2

increases methylation

ISO

Methapyrilene results in increased methylation of SIM2 intron

NCBI chr11:46,883,859...46,923,305
Ensembl chr11:46,883,859...46,923,305

G

SIN3 transcription regulator family member B

increases expression

EXP

Methapyrilene results in increased expression of SIN3B mRNA

NCBI chr16:17,157,352...17,194,051
Ensembl chr16:17,157,352...17,270,664

G

signal-induced proliferation-associated 1 like 3

affects methylation

ISO

Methapyrilene affects the methylation of SIPA1L3 intron

NCBI chr 1:93,746,187...93,953,606
Ensembl chr 1:93,746,192...93,831,268

G

SLAIN motif family, member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLAIN2 intron

NCBI chr14:35,590,050...35,667,734
Ensembl chr14:35,590,057...35,658,684

G

stem-loop histone mRNA binding protein

decreases methylation
increases expression

ISO
EXP

Methapyrilene results in decreased methylation of SLBP intron
Methapyrilene results in increased expression of SLBP mRNA

PMID:30157460 PMID:30467583

NCBI chr14:81,295,479...81,306,446
Ensembl chr14:81,296,223...81,306,447

G

solute carrier family 10 member 1

decreases expression

EXP

Methapyrilene results in decreased expression of SLC10A1 mRNA

PMID:15120968 PMID:28529062

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944

G

solute carrier family 11 member 2

increases expression

ISO

Methapyrilene results in increased expression of SLC11A2 mRNA

NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941

G

solute carrier family 12 member 3

increases methylation

ISO

Methapyrilene results in increased methylation of SLC12A3 intron

NCBI chr19:10,636,594...10,690,008
Ensembl chr19:10,636,596...10,675,050

G

solute carrier family 13 member 2

increases methylation

ISO

Methapyrilene results in increased methylation of SLC13A2 polyA tail

NCBI chr10:63,789,874...63,817,441
Ensembl chr10:63,789,876...63,817,184

G

solute carrier family 13 member 5

decreases expression

EXP

Methapyrilene results in decreased expression of SLC13A5 mRNA

NCBI chr10:57,364,806...57,389,500
Ensembl chr10:57,364,806...57,389,516

G

solute carrier family 14 member 1 (Kidd blood group)

increases methylation

ISO

Methapyrilene results in increased methylation of SLC14A1 intron

NCBI chr18:73,840,568...73,883,925
Ensembl chr18:73,840,569...73,870,489

G

solute carrier family 14 member 2

increases methylation

ISO

Methapyrilene results in increased methylation of SLC14A2 intron

Ensembl chr18:73,887,575...73,953,570

G

solute carrier family 15 member 1

increases methylation

ISO

Methapyrilene results in increased methylation of SLC15A1 intron

NCBI chr15:104,944,461...104,991,316
Ensembl chr15:104,944,463...104,989,369

G

solute carrier family 16 member 2

increases methylation

ISO

Methapyrilene results in increased methylation of SLC16A2 intron

NCBI chr X:72,791,096...72,914,299
Ensembl chr X:72,781,876...72,914,498

G

solute carrier family 16 member 5

increases expression

ISO

Methapyrilene results in increased expression of SLC16A5 mRNA

NCBI chr10:101,206,371...101,220,300
Ensembl chr10:101,206,398...101,220,300

G

solute carrier family 16, member 6

increases methylation

ISO

Methapyrilene results in increased methylation of SLC16A6 intron

NCBI chr10:94,923,888...94,946,990
Ensembl chr10:94,923,888...94,947,965

G

solute carrier family 16 member 7

decreases expression

EXP

Methapyrilene results in decreased expression of SLC16A7 mRNA

NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386

G

solute carrier family 17 member 5

decreases expression

EXP

Methapyrilene results in decreased expression of SLC17A5 mRNA

NCBI chr 8:88,274,497...88,309,734
Ensembl chr 8:88,274,721...88,309,664

G

solute carrier family 1 member 1

increases methylation

ISO

Methapyrilene results in increased methylation of SLC1A1 intron

NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469

G

solute carrier family 1 member 2

decreases expression

EXP

Methapyrilene results in decreased expression of SLC1A2 mRNA

NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249

G

solute carrier family 20 member 2

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of SLC20A2 intron
Methapyrilene results in decreased expression of SLC20A2 mRNA

PMID:30157460 PMID:30467583

NCBI chr16:76,163,315...76,253,881
Ensembl chr16:76,162,922...76,253,881

G

solute carrier family 22, member 18

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC67A1 polyA tail

NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:208,101,136...208,124,380

G

solute carrier family 22, member 23

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of SLC22A23 intron
Methapyrilene results in decreased expression of SLC22A23 mRNA

PMID:30157460 PMID:30467583

NCBI chr17:30,749,445...30,915,139
Ensembl chr17:30,749,445...30,915,139

G

solute carrier family 22 member 4

decreases expression

EXP

Methapyrilene results in decreased expression of SLC22A4 mRNA

NCBI chr10:38,634,098...38,687,409
Ensembl chr10:38,634,098...38,679,920

G

solute carrier family 23 member 1

affects methylation

ISO

Methapyrilene affects the methylation of SLC23A1 intron

NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702

G

solute carrier family 25 member 11

decreases expression

EXP

Methapyrilene results in decreased expression of SLC25A11 mRNA

NCBI chr10:55,856,209...55,859,060
Ensembl chr10:55,855,979...55,859,060

G

solute carrier family 25 member 12

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC25A12 intron

NCBI chr 3:76,504,868...76,599,536
Ensembl chr 3:76,504,868...76,599,536

G

solute carrier family 25 member 13

decreases expression

EXP

Methapyrilene results in decreased expression of SLC25A13 mRNA

NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:35,145,721...35,328,360

G

solute carrier family 25 member 15

decreases expression

EXP

Methapyrilene results in decreased expression of SLC25A15 mRNA

NCBI chr16:76,334,037...76,357,325
Ensembl chr16:76,324,288...76,357,321

G

solute carrier family 25 member 16

decreases expression

EXP

Methapyrilene results in decreased expression of SLC25A16 mRNA

NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,660,339...25,689,285
Ensembl chr20:25,660,339...25,689,285

G

solute carrier family 25 member 17

decreases expression

EXP

Methapyrilene results in decreased expression of SLC25A17 mRNA

NCBI chr 7:114,724,533...114,767,163
Ensembl chr 7:114,724,533...114,767,345

G

solute carrier family 25 member 19

increases expression

EXP

Methapyrilene results in increased expression of SLC25A19 mRNA

NCBI chr10:101,353,426...101,366,551
Ensembl chr10:101,350,106...101,366,351

G

solute carrier family 25 member 20

decreases expression
decreases methylation

EXP
ISO

Methapyrilene results in decreased expression of SLC25A20 mRNA
Methapyrilene results in decreased methylation of SLC25A20 intron

PMID:30157460 PMID:30467583

NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027

G

solute carrier family 25 member 37

increases methylation

ISO

Methapyrilene results in increased methylation of SLC25A37 intron

NCBI chr15:50,944,085...50,986,506
Ensembl chr15:50,946,236...50,986,808

G

solute carrier family 25, member 46

decreases expression

EXP

Methapyrilene results in decreased expression of SLC25A46 mRNA

NCBI chr18:23,490,422...23,519,599
Ensembl chr18:23,490,425...23,518,730

G

solute carrier family 25, member 48

increases methylation
decreases expression

ISO

Methapyrilene results in increased methylation of SLC25A48 intron
Methapyrilene results in decreased expression of SLC25A48 mRNA

PMID:30157460 PMID:31555880

NCBI chr17:8,113,134...8,172,376
Ensembl chr17:8,127,111...8,166,042

G

solute carrier family 27 member 2

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of SLC27A2 polyA tail
Methapyrilene results in decreased methylation of SLC27A2 intron

NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581

G

solute carrier family 27 member 5

increases expression

EXP

Methapyrilene results in increased expression of SLC27A5 mRNA

NCBI chr 1:82,688,742...82,699,335
Ensembl chr 1:82,688,750...82,699,358

G

solute carrier family 29 member 3

increases methylation

ISO

Methapyrilene results in increased methylation of SLC29A3 intron

NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299

G

solute carrier family 2 member 1

affects expression
multiple interactions

EXP

Methapyrilene affects the expression of SLC2A1 mRNA
[Diethylnitrosamine co-treated with Methapyrilene] results in increased expression of SLC2A1 protein

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742

G

solute carrier family 2 member 2

decreases expression

EXP

Methapyrilene results in decreased expression of SLC2A2 mRNA

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467

G

solute carrier family 2 member 3

increases methylation

ISO

Methapyrilene results in increased methylation of SLC2A3 intron

NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186

G

solute carrier family 2 member 4

decreases expression

ISO

Methapyrilene results in decreased expression of SLC2A4 mRNA

NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270

G

solute carrier family 2 member 7

increases methylation

ISO

Methapyrilene results in increased methylation of SLC2A7 intron

NCBI chr 5:165,907,721...165,927,277
Ensembl chr 5:165,907,721...165,926,891

G

solute carrier family 30 member 9

decreases expression

EXP

Methapyrilene results in decreased expression of SLC30A9 mRNA

NCBI chr14:41,170,164...41,224,861
Ensembl chr14:41,170,166...41,224,788

G

solute carrier family 31 member 1

decreases expression

EXP

Methapyrilene results in decreased expression of SLC31A1 mRNA

NCBI chr 5:80,830,574...80,859,810
Ensembl chr 5:80,830,389...80,859,809

G

solute carrier family 33 member 1

decreases expression

EXP

Methapyrilene results in decreased expression of SLC33A1 mRNA

NCBI chr 2:150,565,327...150,587,700
Ensembl chr 2:150,565,328...150,587,416

G

solute carrier family 35, member F3

increases methylation

ISO

Methapyrilene results in increased methylation of SLC35F3 intron

NCBI chr19:71,000,144...71,270,829
Ensembl chr19:71,000,265...71,269,517

G

solute carrier family 36 member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC36A2 intron

NCBI chr10:39,778,667...39,806,781
Ensembl chr10:39,778,693...39,806,773

G

solute carrier family 37 member 1

increases methylation

ISO

Methapyrilene results in increased methylation of SLC37A1 intron

NCBI chr20:9,361,733...9,435,227
Ensembl chr20:9,379,664...9,435,229

G

solute carrier family 38, member 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC38A8 intron

NCBI chr19:64,432,524...64,468,852
Ensembl chr19:64,437,013...64,463,960

G

solute carrier family 39, member 11

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC39A11 intron

NCBI chr10:98,775,155...99,196,302
Ensembl chr10:98,776,525...99,107,368

G

solute carrier family 39 member 14

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of SLC39A14 intron
Methapyrilene results in decreased expression of SLC39A14 mRNA

PMID:30157460 PMID:30467583

NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229

G

solute carrier family 39 member 6

increases expression

EXP

Methapyrilene results in increased expression of SLC39A6 mRNA

NCBI chr18:16,139,621...16,160,163
Ensembl chr18:16,135,008...16,160,163

G

solute carrier family 39 member 8

decreases expression

EXP

Methapyrilene results in decreased expression of SLC39A8 mRNA

NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667

G

solute carrier family 3 member 2

increases expression

EXP

Methapyrilene results in increased expression of SLC3A2 mRNA

NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064

G

solute carrier family 40 member 1

increases expression

ISO

Methapyrilene results in increased expression of SLC40A1 mRNA

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460

G

solute carrier family 41 member 2

decreases expression

EXP

Methapyrilene results in decreased expression of SLC41A2 mRNA

NCBI chr 7:22,271,298...22,378,764
Ensembl chr 7:22,271,313...22,378,764

G

solute carrier family 44 member 1

decreases expression

EXP

Methapyrilene results in decreased expression of SLC44A1 mRNA

NCBI chr 5:72,857,323...73,037,279
Ensembl chr 5:72,858,759...73,037,279

G

solute carrier family 4 member 1 (Diego blood group)

increases methylation

ISO

Methapyrilene results in increased methylation of SLC4A1 intron

NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258

G

solute carrier family 51 member A

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC51A intron

NCBI chr11:81,804,141...81,818,539
Ensembl chr11:81,803,972...81,818,539

G

solute carrier family 5 member 10

increases methylation

ISO

Methapyrilene results in increased methylation of SLC5A10 intron

NCBI chr10:46,851,527...46,898,460
Ensembl chr10:46,851,527...46,899,277

G

solute carrier family 5 member 4

increases methylation

ISO

Methapyrilene results in increased methylation of SLC5A4 intron

NCBI chr20:12,475,096...12,518,186
Ensembl chr20:12,475,096...12,527,506

G

solute carrier family 6 member 1

increases methylation

ISO

Methapyrilene results in increased methylation of SLC6A1 intron

NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:149,004,635...149,037,839

G

solute carrier family 6 member 11

increases methylation

ISO

Methapyrilene results in increased methylation of SLC6A11 intron

NCBI chr 4:148,853,557...148,968,895
Ensembl chr 4:148,853,554...148,969,019

G

solute carrier family 6 member 12

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC6A12 exon

NCBI chr 4:156,257,518...156,275,870
Ensembl chr 4:156,254,208...156,275,879

G

solute carrier family 6 member 17

increases methylation

ISO

Methapyrilene results in increased methylation of SLC6A17 exon; Methapyrilene results in increased methylation of SLC6A17 intron

NCBI chr 2:197,795,622...197,843,883
Ensembl chr 2:197,795,622...197,843,883

G

solute carrier family 6 member 3

increases methylation

ISO

Methapyrilene results in increased methylation of SLC6A3 intron

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962

G

solute carrier family 7 member 1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of SLC7A1 intron
Methapyrilene results in decreased expression of SLC7A1 mRNA

PMID:30157460 PMID:30467583

NCBI chr12:11,664,488...11,740,030
Ensembl chr12:11,664,399...11,740,030

G

solute carrier family 7 member 2

decreases expression

EXP

Methapyrilene results in decreased expression of SLC7A2 mRNA

NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256

G

solute carrier family 7 member 6

increases methylation

ISO

Methapyrilene results in increased methylation of SLC7A6 intron

NCBI chr19:50,982,459...51,010,140
Ensembl chr19:50,984,132...51,010,134

G

solute carrier family 7, member 6 opposite strand

increases expression

EXP

Methapyrilene results in increased expression of SLC7A6OS mRNA

NCBI chr19:51,011,850...51,020,514
Ensembl chr19:51,011,703...51,020,563

G

solute carrier family 7 member 7

increases methylation

ISO

Methapyrilene results in increased methylation of SLC7A7 intron

NCBI chr15:31,792,122...31,852,732
Ensembl chr15:31,792,125...31,835,683

G

solute carrier family 7 member 9

increases methylation

ISO

Methapyrilene results in increased methylation of SLC7A9 intron

NCBI chr 1:97,246,253...97,269,546
Ensembl chr 1:97,247,547...97,269,543

G

solute carrier family 8 member A1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLC8A1 intron

NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:18,946,798...19,287,964

G

solute carrier family 9 member A1

increases methylation

ISO

Methapyrilene results in increased methylation of SLC9A1 intron

NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:150,860,228...150,913,517

G

solute carrier family 9 member A2

increases methylation

ISO

Methapyrilene results in increased methylation of SLC9A2 intron

NCBI chr 9:50,427,612...50,510,043
Ensembl chr 9:50,426,798...50,510,040

G

solute carrier family 9 member A3

increases methylation

ISO

Methapyrilene results in increased methylation of SLC9A3 intron

NCBI chr 1:30,953,215...30,996,209
Ensembl chr 1:30,953,216...30,996,002

G

solute carrier family 9 member B1

increases methylation

ISO

Methapyrilene results in increased methylation of SLC9B1 intron

NCBI chr 2:226,442,892...226,502,966
Ensembl chr 2:226,442,892...226,491,941

G

solute carrier family 9 member B2

increases methylation

ISO

Methapyrilene results in increased methylation of SLC9B2 intron

NCBI chr 2:226,400,358...226,435,039
Ensembl chr 2:226,410,263...226,435,030

G

solute carrier organic anion transporter family, member 1a1

decreases expression

EXP

Methapyrilene results in decreased expression of SLCO1A1 mRNA

NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992

G

solute carrier organic anion transporter family member 1B2

decreases expression

EXP

Methapyrilene results in decreased expression of SLCO1B2 mRNA

NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083

G

solute carrier organic anion transporter family, member 2b1

decreases expression

EXP

Methapyrilene results in decreased expression of SLCO2B1 mRNA

NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279

G

solute carrier organic anion transporter family, member 5A1

increases methylation

ISO

Methapyrilene results in increased methylation of SLCO5A1 intron

NCBI chr 5:11,012,001...11,141,180
Ensembl chr 5:11,012,075...11,141,177

G

slit guidance ligand 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLIT2 intron

NCBI chr14:66,829,661...67,168,517
Ensembl chr14:66,829,661...67,167,146

G

slit guidance ligand 3

increases methylation

ISO

Methapyrilene results in increased methylation of SLIT3 intron

NCBI chr10:20,075,929...20,660,704
Ensembl chr10:20,076,021...20,660,704

G

SLIT and NTRK-like family, member 5

increases methylation

ISO

Methapyrilene results in increased methylation of SLITRK5 exon

NCBI chr15:95,261,397...95,270,465
Ensembl chr15:95,261,005...95,276,090

G

STE20-like kinase

decreases expression

EXP

Methapyrilene results in decreased expression of SLK mRNA

NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829

G

SAFB-like, transcription modulator

increases methylation

ISO

Methapyrilene results in increased methylation of SLTM intron

NCBI chr 8:80,096,555...80,142,668
Ensembl chr 8:80,097,652...80,142,671

G

secreted Ly6/Plaur domain containing 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SLURP2 promoter

NCBI chr 7:108,516,758...108,520,638
Ensembl chr 7:108,516,758...108,520,638

G

SLX4 interacting protein

increases methylation

ISO

Methapyrilene results in increased methylation of SLX4IP intron

NCBI chr 3:144,672,898...144,849,468
Ensembl chr 3:144,673,857...144,849,465
Ensembl chr 8:144,673,857...144,849,465

G

SLX9 ribosome biogenesis factor

increases methylation

ISO

Methapyrilene results in increased methylation of SLX9 intron

NCBI chr20:11,114,214...11,147,112
Ensembl chr20:11,114,214...11,147,085

G

SMAD family member 3

increases methylation

ISO

Methapyrilene results in increased methylation of SMAD3 intron

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324

G

SMAD family member 6

decreases methylation

ISO

Methapyrilene results in decreased methylation of SMAD6 intron

NCBI chr 8:73,345,457...73,414,985
Ensembl chr 8:73,345,460...73,414,149

G

SMAD family member 7

increases methylation

ISO

Methapyrilene results in increased methylation of SMAD7 intron

NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

increases methylation

ISO

Methapyrilene results in increased methylation of SMARCA2 intron

NCBI chr 1:233,617,277...233,784,908
Ensembl chr 1:233,617,366...233,784,869

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

increases methylation

ISO

Methapyrilene results in increased methylation of SMARCA4 intron

NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:28,443,810...28,535,070

G

SWI/SNF related BAF chromatin remodeling complex subunit D3

increases methylation

ISO

Methapyrilene results in increased methylation of SMARCD3 intron

NCBI chr 4:11,441,142...11,472,781
Ensembl chr 4:11,441,157...11,472,781

G

structural maintenance of chromosomes 1A

decreases expression

EXP

Methapyrilene results in decreased expression of SMC1A mRNA

NCBI chr X:24,582,732...24,627,462
Ensembl chr X:24,582,690...24,627,462

G

structural maintenance of chromosomes 2

increases expression

EXP

Methapyrilene results in increased expression of SMC2 mRNA

NCBI chr 5:71,592,428...71,648,636
Ensembl chr 5:71,602,308...71,648,632

G

small integral membrane protein 11

increases methylation

ISO

Methapyrilene results in increased methylation of SMIM11 intron

NCBI chr11:45,019,269...45,028,926
Ensembl chr11:45,019,239...45,028,921

G

SPARC related modular calcium binding 1

decreases expression

EXP

Methapyrilene results in decreased expression of SMOC1 mRNA

NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956

G

SPARC related modular calcium binding 2

increases methylation

ISO

Methapyrilene results in increased methylation of SMOC2 intron

NCBI chr 1:63,935,627...64,064,952
Ensembl chr 1:63,935,647...64,064,955

G

sphingomyelin phosphodiesterase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of SMPD3 intron

NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936

G

sphingomyelin phosphodiesterase, acid-like 3B

increases methylation

ISO

Methapyrilene results in increased methylation of SMPDL3B exon

NCBI chr 5:150,228,607...150,250,688
Ensembl chr 5:150,228,611...150,250,688

G

smoothelin-like 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SMTNL2 intron

NCBI chr10:57,506,873...57,528,050
Ensembl chr10:57,506,873...57,528,050

G

SMAD specific E3 ubiquitin protein ligase 1

increases methylation

ISO

Methapyrilene results in increased methylation of SMURF1 intron

NCBI chr12:14,748,717...14,840,273
Ensembl chr12:14,749,043...14,840,273

G

synuclein, alpha interacting protein

increases methylation

ISO

Methapyrilene results in increased methylation of SNCAIP intron

NCBI chr18:48,402,164...48,542,246
Ensembl chr18:48,404,531...48,574,002

G

staphylococcal nuclease and tudor domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of SND1 intron

NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:58,060,640...58,459,925

G

small nucleolar RNA, C/D box 102

increases methylation

ISO

Methapyrilene results in increased methylation of SNORD102 promoter

NCBI chr12:13,384,150...13,384,220
Ensembl chr12:13,384,150...13,384,220

G

syntaphilin

decreases methylation

ISO

Methapyrilene results in decreased methylation of SNPH intron

NCBI chr 3:160,558,929...160,603,636
Ensembl chr 3:160,560,097...160,599,728

G

small nuclear ribonucleoprotein U5 subunit 40

increases methylation

EXP

Methapyrilene results in increased methylation of SNRNP40 gene

NCBI chr 5:147,984,758...148,017,932
Ensembl chr 5:147,984,656...148,018,725

G

small nuclear ribonucleoprotein U11/U12 subunit 48

increases expression

EXP

Methapyrilene results in increased expression of SNRNP48 mRNA

NCBI chr17:26,801,818...26,821,605
Ensembl chr17:26,780,344...26,821,592

G

small nuclear ribonucleoprotein D1 polypeptide

increases expression

EXP

Methapyrilene results in increased expression of SNRPD1 mRNA

NCBI chr18:1,969,351...1,980,207
Ensembl chr18:1,969,674...1,980,207

G

syntrophin, gamma 2

increases methylation

ISO

Methapyrilene results in increased methylation of SNTG2 intron

NCBI chr 6:52,529,481...52,730,972
Ensembl chr 6:52,529,481...52,730,972

G

sorting nexin 14

decreases expression

EXP

Methapyrilene results in decreased expression of SNX14 mRNA

NCBI chr 8:98,053,769...98,278,287
Ensembl chr 8:98,186,714...98,270,451

G

sorting nexin 24

increases methylation

ISO

Methapyrilene results in increased methylation of SNX24 intron

NCBI chr18:48,869,804...49,024,352
Ensembl chr18:48,869,882...49,024,350

G

sorting nexin 25

decreases methylation

ISO

Methapyrilene results in decreased methylation of SNX25 intron

NCBI chr16:52,867,102...52,971,028
Ensembl chr16:52,858,532...52,971,008

G

sorting nexin 29

increases methylation

ISO

Methapyrilene results in increased methylation of SNX29 intron

NCBI chr10:4,391,866...4,805,682
Ensembl chr10:4,394,544...4,813,772

G

sorting nexin 31

increases methylation

ISO

Methapyrilene results in increased methylation of SNX31 intron

NCBI chr 7:69,560,948...69,662,015
Ensembl chr 7:69,553,205...69,617,396

G

sterol O-acyltransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of SOAT1 mRNA

NCBI chr13:71,105,178...71,147,776
Ensembl chr13:71,105,178...71,147,672

G

sine oculis binding protein homolog

increases methylation

ISO

Methapyrilene results in increased methylation of SOBP intron

NCBI chr20:48,064,445...48,243,607
Ensembl chr20:48,064,445...48,243,607

G

suppressor of cytokine signaling 2

increases expression

EXP

Methapyrilene results in increased expression of SOCS2 mRNA

NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423

G

SON DNA and RNA binding protein

decreases expression

EXP

Methapyrilene results in decreased expression of SON mRNA

NCBI chr11:44,336,818...44,409,127
Ensembl chr11:44,377,976...44,409,127

G

sorbin and SH3 domain containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of SORBS2 intron

NCBI chr16:53,167,795...53,481,300
Ensembl chr16:53,167,827...53,358,986

G

sortilin-related VPS10 domain containing receptor 2

affects methylation
increases methylation

ISO

Methapyrilene affects the methylation of SORCS2 intron
Methapyrilene results in increased methylation of SORCS2 exon

NCBI chr14:78,592,290...78,960,582
Ensembl chr14:78,596,087...78,960,582

G

sortilin related receptor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SORL1 intron

NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:51,238,722...51,401,446

G

SOS Ras/Rac guanine nucleotide exchange factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of SOS1 intron

NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350

G

sclerostin

increases methylation

ISO

Methapyrilene results in increased methylation of SOST promoter

NCBI chr10:87,412,722...87,415,766
Ensembl chr10:87,411,721...87,415,766

G

sosondowah ankyrin repeat domain family member C

decreases expression

EXP

Methapyrilene results in decreased expression of SOWAHC mRNA

NCBI chr20:27,738,247...27,742,713
Ensembl chr20:27,736,326...27,752,912

G

SRY-box transcription factor 5

increases methylation

ISO

Methapyrilene results in increased methylation of SOX5 intron

NCBI chr 4:178,512,272...179,467,686
Ensembl chr 4:178,512,272...178,938,495

G

SRY-box transcription factor 9

increases expression

ISO

Methapyrilene results in increased expression of SOX9 protein

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

Sp1 transcription factor

decreases expression

EXP

Methapyrilene results in decreased expression of SP1 mRNA

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

sperm associated antigen 16

increases methylation

ISO

Methapyrilene results in increased methylation of SPAG16 intron

NCBI chr 9:78,782,596...79,702,265
Ensembl chr 9:78,782,614...78,877,630

G

spartin

decreases expression

EXP

Methapyrilene results in decreased expression of SPART mRNA

NCBI chr 2:141,442,770...141,469,388
Ensembl chr 2:141,442,737...141,469,382

G

spermatogenesis associated 13

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPATA13 intron

NCBI chr15:38,954,585...39,083,752
Ensembl chr15:38,810,386...39,083,755

G

spermatogenesis associated 21

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPATA21 intron

NCBI chr 5:158,676,224...158,701,567
Ensembl chr 5:158,676,288...158,701,798

G

spermatogenesis associated 25

increases methylation

ISO

Methapyrilene results in increased methylation of SPATA25 promoter

NCBI chr 3:173,981,863...173,983,818
Ensembl chr 3:173,981,866...173,983,818

G

signal peptidase complex subunit 3

decreases expression

EXP

Methapyrilene results in decreased expression of SPCS3 mRNA

NCBI chr16:44,038,421...44,043,855
Ensembl chr16:44,038,278...44,046,394

G

speedy/RINGO cell cycle regulator family member E4

increases methylation

ISO

Methapyrilene results in increased methylation of SPDYE4 3' UTR

NCBI chr12:16,450,833...16,458,330
Ensembl chr12:16,450,868...16,458,327

G

striated muscle enriched protein kinase

increases methylation

ISO

Methapyrilene results in increased methylation of SPEG intron; Methapyrilene results in increased methylation of SPEG promoter

NCBI chr 9:84,314,387...84,371,816
Ensembl chr 9:84,314,387...84,371,813

G

SPHK1 interactor, AKAP domain containing

increases methylation

ISO

Methapyrilene results in increased methylation of SPHKAP intron

NCBI chr 9:91,957,497...92,105,834
Ensembl chr 9:91,957,497...92,105,625

G

Spi-1 proto-oncogene

increases methylation
decreases methylation

ISO

Methapyrilene results in increased methylation of SPI1 exon
Methapyrilene results in decreased methylation of SPI1 intron

NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540

G

scaffold protein involved in DNA repair

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of SPIDR intron
Methapyrilene results in increased methylation of SPIDR intron

NCBI chr11:98,270,779...98,511,760
Ensembl chr11:98,270,224...98,528,748

G

spindlin 1

increases methylation

ISO

Methapyrilene results in increased methylation of SPIN1 intron

NCBI chr17:14,207,384...14,257,330
Ensembl chr17:14,207,384...14,257,190

G

serine peptidase inhibitor, Kazal type 1

increases expression

EXP

Methapyrilene results in increased expression of SPINK1 mRNA

NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545

G

serine peptidase inhibitor, Kunitz type, 2

increases methylation

ISO

Methapyrilene results in increased methylation of SPINT2 intron

NCBI chr 1:93,685,637...93,708,091
Ensembl chr 1:93,685,641...93,708,091

G

spire-type actin nucleation factor 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPIRE2 intron

NCBI chr19:68,281,878...68,320,427
Ensembl chr19:68,281,870...68,320,427

G

sparc/osteonectin, cwcv and kazal like domains proteoglycan 1

increases methylation

ISO

Methapyrilene results in increased methylation of SPOCK1 intron

NCBI chr17:6,746,892...7,227,034
Ensembl chr17:6,747,646...7,230,282

G

spondin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPON1 intron

NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:177,363,197...177,662,676

G

secreted phosphoprotein 1

increases expression

EXP

Methapyrilene results in increased expression of SPP1 mRNA

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

secreted phosphoprotein 2

increases expression

EXP

Methapyrilene results in increased expression of SPP2 mRNA

NCBI chr 9:96,454,636...96,474,453
Ensembl chr 9:96,454,957...96,474,452

G

signal peptide peptidase-like 2A

increases methylation

ISO

Methapyrilene results in increased methylation of SPPL2A intron

NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:134,605,750...134,646,752

G

signal peptide peptidase like 3

increases methylation

ISO

Methapyrilene results in increased methylation of SPPL3 intron

NCBI chr12:47,176,317...47,260,756
Ensembl chr12:47,176,804...47,260,482

G

splA/ryanodine receptor domain and SOCS box containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of SPSB1 intron

NCBI chr 5:165,641,255...165,701,482
Ensembl chr 5:165,642,851...165,654,225

G

spectrin, beta, non-erythrocytic 1

decreases expression

EXP

Methapyrilene results in decreased expression of SPTBN1 mRNA

NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836

G

spectrin, beta, non-erythrocytic 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPTBN2 intron

NCBI chr 1:211,432,373...211,473,016
Ensembl chr 1:211,432,373...211,473,306

G

serine palmitoyltransferase, long chain base subunit 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPTLC2 intron

NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:112,679,623...112,762,640

G

serine palmitoyltransferase, long chain base subunit 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of SPTLC3 intron

NCBI chr 3:147,301,570...147,431,696
Ensembl chr 3:147,301,801...147,434,044

G

serine palmitoyltransferase, small subunit A

decreases expression

EXP

Methapyrilene results in decreased expression of SPTSSA mRNA

NCBI chr 6:77,879,931...77,891,344
Ensembl chr 6:77,879,941...77,891,403

G

S1 RNA binding domain 1

decreases expression

EXP

Methapyrilene results in decreased expression of SRBD1 mRNA

NCBI chr 6:14,226,551...14,417,494
Ensembl chr 6:14,228,461...14,443,047

G

SRC proto-oncogene, non-receptor tyrosine kinase

increases methylation

ISO

Methapyrilene results in increased methylation of SRC intron

NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462

G

Snf2-related CREBBP activator protein

increases methylation

ISO

Methapyrilene results in increased methylation of SRCAP intron

NCBI chr 1:191,554,043...191,607,096
Ensembl chr 1:191,554,043...191,604,265

G

splicing regulatory glutamic acid and lysine rich protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of SREK1 mRNA

NCBI chr 2:36,583,412...36,618,978
Ensembl chr 2:36,583,412...36,619,001

G

SREK1-interacting protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of SREK1IP1 mRNA

NCBI chr 2:37,709,712...37,733,391
Ensembl chr 2:37,709,768...37,733,383
Ensembl chr 7:37,709,768...37,733,383

G

SLIT-ROBO Rho GTPase activating protein 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of SRGAP3 intron

NCBI chr 4:147,391,082...147,626,407
Ensembl chr 4:147,395,880...147,625,713

G

sorcin

decreases expression

EXP

Methapyrilene results in decreased expression of SRI mRNA

NCBI chr 4:26,928,338...26,952,980
Ensembl chr 4:26,923,662...26,961,361

G

sarcalumenin

decreases methylation

ISO

Methapyrilene results in decreased methylation of SRL intron

NCBI chr10:11,540,365...11,584,506
Ensembl chr10:11,540,443...11,584,504

G

signal recognition particle 54A

decreases expression

EXP

Methapyrilene results in decreased expression of SRP54A mRNA

NCBI chr 6:78,322,308...78,362,017
Ensembl chr 6:78,322,721...78,362,031

G

signal recognition particle 72

decreases expression

EXP

Methapyrilene results in decreased expression of SRP72 mRNA

NCBI chr14:31,522,424...31,549,978
Ensembl chr14:31,522,963...31,550,151

G

SRP receptor subunit alpha

decreases expression

EXP

Methapyrilene results in decreased expression of SRPRA mRNA

NCBI chr 8:41,818,199...41,824,292
Ensembl chr 8:41,818,229...41,824,280

G

serine/arginine repetitive matrix 2

decreases expression

EXP

Methapyrilene results in decreased expression of SRRM2 mRNA

NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337

G

serine and arginine rich splicing factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of SRSF1 mRNA

NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548

G

serine and arginine rich splicing factor 5

decreases expression

EXP

Methapyrilene results in decreased expression of SRSF5 mRNA

NCBI chr 6:106,333,998...106,341,467
Ensembl chr 6:106,336,756...106,341,931

G

sulfiredoxin 1

increases expression

ISO

Methapyrilene results in increased expression of SRXN1 protein

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765

G

single stranded DNA binding protein 1

decreases expression

EXP

Methapyrilene results in decreased expression of SSBP1 mRNA

NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700

G

single-stranded DNA binding protein 2

affects methylation

ISO

Methapyrilene affects the methylation of SSBP2 intron

NCBI chr 2:24,385,494...24,673,768
Ensembl chr 2:24,385,687...24,673,768

G

single stranded DNA binding protein 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of SSBP3 intron

NCBI chr 5:126,920,145...127,057,968
Ensembl chr 5:126,919,120...127,056,799

G

SCO-spondin

increases methylation

ISO

Methapyrilene results in increased methylation of SSPOP intron

NCBI chr 4:78,725,829...78,781,330
Ensembl chr 4:78,727,275...78,781,315

G

signal sequence receptor subunit 2

increases methylation

ISO

Methapyrilene results in increased methylation of SSR2 intron; Methapyrilene results in increased methylation of SSR2 promoter

NCBI chr 2:176,346,117...176,354,868
Ensembl chr 2:176,346,404...176,355,781

G

signal sequence receptor subunit 3

decreases expression

EXP

Methapyrilene results in decreased expression of SSR3 mRNA

NCBI chr 2:151,915,101...151,935,162
Ensembl chr 2:151,906,149...151,935,170

G

ST18 C2H2C-type zinc finger transcription factor

increases methylation

ISO

Methapyrilene results in increased methylation of ST18 5' UTR

NCBI chr 5:17,369,383...17,701,094
Ensembl chr 5:17,371,000...17,458,676

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

increases methylation

ISO

Methapyrilene results in increased methylation of ST3GAL4 intron

NCBI chr 8:41,673,510...41,723,158
Ensembl chr 8:41,673,510...41,712,551

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

decreases expression

EXP

Methapyrilene results in decreased expression of ST3GAL6 mRNA

NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of ST8SIA1 intron

NCBI chr 4:177,513,966...177,651,553
Ensembl chr 4:177,520,926...177,651,553

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

affects methylation

ISO

Methapyrilene affects the methylation of ST8SIA2 intron

NCBI chr 1:137,172,354...137,247,796
Ensembl chr 1:137,172,354...137,247,792

G

stabilin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of STAB1 exon

NCBI chr16:6,336,871...6,367,374
Ensembl chr16:6,336,871...6,364,579

G

STAG2 cohesin complex component

increases methylation

ISO

Methapyrilene results in increased methylation of STAG2 intron

NCBI chr X:125,839,660...125,971,209
Ensembl chr X:125,840,401...125,971,209

G

signal transducing adaptor family member 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of STAP1 intron

NCBI chr14:22,301,278...22,336,218
Ensembl chr14:22,236,616...22,342,652

G

signal transducing adaptor family member 2

decreases expression

EXP

Methapyrilene results in decreased expression of STAP2 mRNA

NCBI chr 9:915,546...924,604
Ensembl chr 9:915,550...924,380

G

StAR-related lipid transfer domain containing 13

decreases methylation

ISO

Methapyrilene results in decreased methylation of STARD13 intron

NCBI chr12:5,401,878...5,797,937
Ensembl chr12:5,401,995...5,794,967

G

STARD3 N-terminal like

increases methylation

ISO

Methapyrilene results in increased methylation of STARD3NL intron

NCBI chr17:50,278,859...50,312,864
Ensembl chr17:50,278,894...50,312,866

G

StAR-related lipid transfer domain containing 8

increases methylation

ISO

Methapyrilene results in increased methylation of STARD8 intron

NCBI chr X:68,119,276...68,236,247
Ensembl chr X:68,119,644...68,236,246

G

signal transducer and activator of transcription 3

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of STAT3 intron
Methapyrilene results in decreased expression of STAT3 mRNA

PMID:30157460 PMID:30467583

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

serine/threonine kinase 10

increases methylation

ISO

Methapyrilene results in increased methylation of STK10 intron

NCBI chr10:17,622,149...17,716,337
Ensembl chr10:17,622,162...17,716,332

G

serine/threonine kinase 17b

increases methylation

ISO

Methapyrilene results in increased methylation of STK17B intron

NCBI chr 9:62,801,912...62,832,511
Ensembl chr 9:62,803,005...62,832,511

G

serine/threonine kinase 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of STK3 intron

NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:67,938,378...68,208,508

G

serine/threonine kinase 32B

increases methylation

ISO

Methapyrilene results in increased methylation of STK32B intron

NCBI chr14:77,300,675...77,562,721
Ensembl chr14:77,302,755...77,562,721

G

serine/threonine kinase 32C

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of STK32C intron
Methapyrilene results in increased methylation of STK32C polyA tail

NCBI chr 1:203,330,325...203,411,325
Ensembl chr 1:203,330,325...203,411,325

G

serine/threonine kinase 36

decreases methylation

ISO

Methapyrilene results in decreased methylation of STK36 intron

NCBI chr 9:83,625,905...83,652,785
Ensembl chr 9:83,626,030...83,653,525

G

serine threonine kinase 39

increases methylation

ISO

Methapyrilene results in increased methylation of STK39 intron

NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:73,321,522...73,586,740

G

stathmin 1

increases expression

EXP

Methapyrilene results in increased expression of STMN1 mRNA

PMID:15890375 PMID:22484513 PMID:22584684 PMID:30467583

NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842

G

stomatin like 1

increases methylation

ISO

Methapyrilene results in increased methylation of STOML1 3' UTR

NCBI chr 8:67,557,846...67,565,734
Ensembl chr 8:67,557,847...67,565,730

G

storkhead box 1

increases methylation

ISO

Methapyrilene results in increased methylation of STOX1 intron

NCBI chr20:31,140,993...31,209,126
Ensembl chr20:31,140,993...31,208,877

G

storkhead box 2

increases methylation

ISO

Methapyrilene results in increased methylation of STOX2 intron

NCBI chr16:51,580,855...51,819,909
Ensembl chr16:51,580,798...51,815,209

G

sperm-tail PG-rich repeat containing 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of STPG3 promoter

NCBI chr 3:28,426,283...28,432,857
Ensembl chr 3:28,426,292...28,428,692

G

sperm-tail PG-rich repeat containing 4

increases methylation

ISO

Methapyrilene results in increased methylation of STPG4 intron

NCBI chr 6:12,860,749...12,912,206
Ensembl chr 6:12,861,976...12,904,932

G

stimulated by retinoic acid 8

increases methylation

ISO

Methapyrilene results in increased methylation of STRA8 intron

NCBI chr 4:64,568,580...64,591,914
Ensembl chr 4:64,568,706...64,591,911

G

spermatid perinuclear RNA binding protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of STRBP intron

NCBI chr 3:41,738,096...41,879,054
Ensembl chr 3:41,712,311...41,824,707

G

STT3 oligosaccharyltransferase complex catalytic subunit A

decreases expression

EXP

Methapyrilene results in decreased expression of STT3A mRNA

NCBI chr 8:44,632,473...44,671,960
Ensembl chr 8:44,632,473...44,672,226

G

syntaxin 19

increases methylation

ISO

Methapyrilene results in increased methylation of STX19 intron

NCBI chr11:13,619,436...13,624,634
Ensembl chr11:13,593,134...13,629,410

G

syntaxin binding protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of STXBP1 intron

NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:36,474,428...36,536,058

G

serine/threonine/tyrosine interacting-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of STYXL1 mRNA

NCBI chr12:26,544,059...26,576,365
Ensembl chr12:26,544,067...26,576,366

G

succinate-CoA ligase ADP-forming subunit beta

decreases expression

EXP

Methapyrilene results in decreased expression of SUCLA2 protein

NCBI chr15:55,161,894...55,215,031
Ensembl chr15:55,161,868...55,215,029

G

succinate-CoA ligase GDP-forming subunit beta

decreases expression

EXP

Methapyrilene results in decreased expression of SUCLG2 protein

NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:129,623,834...129,937,296

G

SURP and G patch domain containing 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of SUGP1 intron

NCBI chr16:19,386,588...19,417,460
Ensembl chr16:19,386,589...19,417,460

G

sulfatase 2

increases methylation

ISO

Methapyrilene results in increased methylation of SULF2 intron

NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651

G

sulfotransferase family 1A member 1

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of SULT1A1 mRNA
Methapyrilene results in increased methylation of SULT1A1 intron

PMID:16393664 PMID:23274394 PMID:30157460 PMID:30467583

NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131

G

sulfotransferase family 1C member 3

decreases expression
increases expression

EXP

Methapyrilene results in decreased expression of SULT1C1 mRNA
Methapyrilene results in increased expression of SULT1C3 mRNA

PMID:15120968 PMID:30467583

NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295

G

sulfite oxidase

decreases expression

EXP

Methapyrilene results in decreased expression of SUOX mRNA

NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,687,666...1,690,235

G

synaptonemal complex protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of SYCP1 intron

NCBI chr 2:192,985,164...193,145,234
Ensembl chr 2:192,984,621...193,145,421

G

symplekin scaffold protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of SYMPK intron

NCBI chr 1:87,800,416...87,828,727
Ensembl chr 1:87,799,853...87,828,727

G

synapsin II

increases methylation

ISO

Methapyrilene results in increased methylation of SYN2 intron

NCBI chr 4:149,858,919...150,016,845
Ensembl chr 4:149,851,520...150,019,650

G

synapsin III

affects methylation

ISO

Methapyrilene affects the methylation of SYN3 intron

NCBI chr 7:19,244,032...19,701,571
Ensembl chr 7:19,264,094...19,696,510

G

synapse differentiation inducing 1

increases methylation

ISO

Methapyrilene results in increased methylation of SYNDIG1 exon; Methapyrilene results in increased methylation of SYNDIG1 intron

NCBI chr 3:158,491,474...158,695,174
Ensembl chr 3:158,491,996...158,658,652

G

spectrin repeat containing nuclear envelope protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of SYNE1 intron

NCBI chr 1:43,917,640...44,388,802
Ensembl chr 1:43,895,994...44,388,721

G

spectrin repeat containing nuclear envelope protein 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of SYNE2 intron

NCBI chr 6:100,272,729...100,586,364
Ensembl chr 6:100,272,729...100,583,723

G

spectrin repeat containing nuclear envelope family member 4

increases methylation

ISO

Methapyrilene results in increased methylation of SYNE4 exon

NCBI chr 1:94,696,866...94,701,230
Ensembl chr 1:94,696,609...94,701,230

G

synaptogyrin 1

increases methylation

ISO

Methapyrilene results in increased methylation of SYNGR1 3' UTR

NCBI chr 7:113,516,246...113,542,918
Ensembl chr 7:113,516,265...113,542,917

G

synaptopodin

decreases expression

ISO

Methapyrilene results in decreased expression of SYNPO mRNA

NCBI chr18:56,326,369...56,347,359
Ensembl chr18:56,319,571...56,353,306

G

synaptotagmin 12

increases methylation

ISO

Methapyrilene results in increased methylation of SYT12 intron

NCBI chr 1:211,158,745...211,189,780
Ensembl chr 1:211,159,800...211,189,037

G

synaptotagmin 6

increases methylation

ISO

Methapyrilene results in increased methylation of SYT6 intron

NCBI chr 2:193,781,051...193,840,741
Ensembl chr 2:193,781,476...193,840,741

G

synaptotagmin-like 3

increases methylation

ISO

Methapyrilene results in increased methylation of SYTL3 intron

NCBI chr 1:49,300,935...49,372,533
Ensembl chr 1:49,302,182...49,372,531

G

synoviolin 1

decreases expression

EXP

Methapyrilene results in decreased expression of SYVN1 mRNA

NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:212,768,907...212,776,457

G

TGF-beta activated kinase 1 (MAP3K7) binding protein 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of TAB3 intron

NCBI chr X:53,923,473...53,995,777
Ensembl chr X:53,923,492...53,995,610

G

transforming, acidic coiled-coil containing protein 2

increases methylation

ISO

Methapyrilene results in increased methylation of TACC2 intron

NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152

G

transcriptional adaptor 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TADA1 intron

NCBI chr13:81,165,871...81,180,421
Ensembl chr13:81,165,850...81,188,495

G

transcriptional adaptor 2B

decreases expression

EXP

Methapyrilene results in decreased expression of TADA2B mRNA

NCBI chr14:78,503,939...78,523,715
Ensembl chr14:78,503,644...78,515,436

G

TATA-box binding protein associated factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of TAF1 mRNA

NCBI chr X:70,680,901...70,756,535
Ensembl chr X:70,680,906...70,756,735

G

TATA-box binding protein associated factor 15

decreases methylation

ISO

Methapyrilene results in decreased methylation of TAF15 intron

NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,770,430...68,802,458

G

TATA-box binding protein associated factor, RNA polymerase I subunit D

increases expression

EXP

Methapyrilene results in increased expression of TAF1D mRNA

NCBI chr 8:20,427,894...20,438,046
Ensembl chr 8:20,427,954...20,434,556

G

TAFA chemokine like family member 5

increases methylation

ISO

Methapyrilene results in increased methylation of TAFA5 intron

NCBI chr 7:120,493,447...120,714,720
Ensembl chr 7:120,493,060...120,714,718

G

transgelin

increases expression

EXP

Methapyrilene results in increased expression of TAGLN mRNA

NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563

G

transaldolase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TALDO1 polyA tail

NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535

G

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

increases methylation

ISO

Methapyrilene results in increased methylation of TANC2 intron

NCBI chr10:91,052,860...91,373,291
Ensembl chr10:91,053,067...91,368,570

G

transport and golgi organization 6 homolog

increases methylation

ISO

Methapyrilene results in increased methylation of TANGO6 intron

NCBI chr19:51,479,384...51,667,142
Ensembl chr19:51,479,391...51,687,621

G

TAO kinase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TAOK1 intron

NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,871,198...62,957,595

G

TAO kinase 2

increases expression

EXP

Methapyrilene results in increased expression of TAOK2 mRNA

NCBI chr 1:190,906,236...190,925,359
Ensembl chr 1:190,906,239...190,925,140

G

transporter 1, ATP binding cassette subfamily B member

increases expression

EXP

Methapyrilene results in increased expression of TAP1 mRNA

NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810

G

TAP binding protein

decreases methylation

ISO

Methapyrilene results in decreased methylation of TAPBP exon

NCBI chr20:4,958,821...4,967,958
Ensembl chr20:4,959,926...4,971,834

G

TLR adaptor interacting with endolysosomal SLC15A4

decreases methylation

ISO

Methapyrilene results in decreased methylation of TASL intron

NCBI chr X:54,354,755...54,373,930
Ensembl chr X:54,312,036...54,374,144

G

taspase 1

decreases expression

EXP

Methapyrilene results in decreased expression of TASP1 mRNA

NCBI chr 3:147,630,092...147,861,710
Ensembl chr 3:147,630,092...147,861,654

G

tyrosine aminotransferase

increases expression
decreases expression

EXP

Methapyrilene results in increased expression of TAT mRNA
Methapyrilene results in decreased expression of TAT mRNA

PMID:15890375 PMID:22484513 PMID:30467583

NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482

G

TatD DNase domain containing 2

increases expression

EXP

Methapyrilene results in increased expression of TATDN2 mRNA

NCBI chr 4:148,400,454...148,416,501
Ensembl chr 4:148,400,492...148,416,501

G

TBC1 domain family, member 14

increases methylation

ISO

Methapyrilene results in increased methylation of TBC1D14 intron

NCBI chr14:78,397,345...78,496,863
Ensembl chr14:78,397,355...78,496,865

G

TBC1 domain family, member 15

increases methylation

ISO

Methapyrilene results in increased methylation of TBC1D15 intron

NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303

G

TBC1 domain family, member 17

decreases expression

EXP

Methapyrilene results in decreased expression of TBC1D17 mRNA

NCBI chr 1:104,461,266...104,469,615
Ensembl chr 1:104,461,267...104,469,489

G

TBC1 domain family, member 22a

affects methylation

ISO

Methapyrilene affects the methylation of TBC1D22A intron

NCBI chr 7:119,172,284...119,457,271
Ensembl chr 7:119,172,333...119,457,271

G

TBC1 domain family, member 5

increases methylation

ISO

Methapyrilene results in increased methylation of TBC1D5 intron

NCBI chr 9:3,740,032...4,256,971
Ensembl chr 9:3,750,325...4,253,581

G

TBCC domain containing 1

decreases expression

EXP

Methapyrilene results in decreased expression of TBCCD1 mRNA

NCBI chr11:91,672,948...91,710,120
Ensembl chr11:91,672,964...91,709,883

G

tubulin folding cofactor D

increases methylation

ISO

Methapyrilene results in increased methylation of TBCD intron

NCBI chr10:107,215,626...107,372,398
Ensembl chr10:107,215,633...107,372,402

G

transducin (beta)-like 1 X-linked

decreases expression

EXP

Methapyrilene results in decreased expression of TBL1X mRNA

NCBI chr X:45,452,983...45,609,532
Ensembl chr X:45,454,482...45,609,525

G

TBL1X/Y related 1

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of TBL1XR1 intron
Methapyrilene results in decreased expression of TBL1XR1 mRNA

PMID:30157460 PMID:30467583

NCBI chr 2:106,718,811...106,857,989
Ensembl chr 2:106,730,665...106,857,989

G

T-box transcription factor 20

increases methylation

ISO

Methapyrilene results in increased methylation of TBX20 intron

NCBI chr 8:31,475,963...31,534,051
Ensembl chr 8:31,475,963...31,534,009

G

transcription elongation factor A1

increases methylation

ISO

Methapyrilene results in increased methylation of TCEA1 intron

NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156
Ensembl chr 5:12,831,339...12,834,156

G

transcription elongation factor A like 9

increases methylation

ISO

Methapyrilene results in increased methylation of TCEAL9 polyA tail

NCBI chr X:104,037,274...104,039,345
Ensembl chr X:104,032,421...104,041,562

G

transcription elongation regulator 1

decreases expression

EXP

Methapyrilene results in decreased expression of TCERG1 mRNA

NCBI chr18:34,756,558...34,817,441
Ensembl chr18:34,756,725...34,817,441

G

transcription elongation regulator 1-like

increases methylation

ISO

Methapyrilene results in increased methylation of TCERG1L intron

NCBI chr 1:202,442,605...202,630,483
Ensembl chr 1:202,442,605...202,630,769

G

TCF25 ribosome quality control complex subunit

decreases methylation

ISO

Methapyrilene results in decreased methylation of TCF25 intron

NCBI chr19:68,323,789...68,358,226
Ensembl chr19:68,323,867...68,358,240

G

transcription factor 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of TCF4 intron

NCBI chr18:65,216,840...65,563,186
Ensembl chr18:65,216,849...65,558,401

G

transcription factor 7

decreases methylation

ISO

Methapyrilene results in decreased methylation of TCF7 intron

NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,924,363...36,954,279

G

transcription factor 7 like 2

decreases expression

EXP

Methapyrilene results in decreased expression of TCF7L2 mRNA

NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225

G

trichohyalin

decreases methylation

ISO

Methapyrilene results in decreased methylation of TCHH exon

NCBI chr 2:181,787,109...181,795,463
Ensembl chr 2:181,787,109...181,795,463

G

tryptophan 2,3-dioxygenase

decreases expression

EXP

Methapyrilene results in decreased expression of TDO2 mRNA

NCBI chr 2:169,567,656...169,585,586
Ensembl chr 2:169,567,654...169,585,586

G

tudor domain containing 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of TDRD3 intron

NCBI chr15:69,748,754...69,911,605
Ensembl chr15:69,749,217...69,884,656

G

tudor domain containing 9

increases methylation

ISO

Methapyrilene results in increased methylation of TDRD9 intron

NCBI chr 6:136,850,797...136,966,225
Ensembl chr 6:136,850,812...136,966,225

G

TEA domain transcription factor 4

increases methylation

ISO

Methapyrilene results in increased methylation of TEAD4 intron

NCBI chr 4:163,180,192...163,258,342
Ensembl chr 4:163,180,192...163,258,479

G

TEK receptor tyrosine kinase

increases expression

EXP

Methapyrilene results in increased expression of TEK mRNA

NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991

G

teneurin transmembrane protein 3

increases methylation

ISO

Methapyrilene results in increased methylation of TENM3 3' UTR

NCBI chr16:47,984,732...50,711,352
Ensembl chr16:49,829,750...50,711,352

G

teneurin transmembrane protein 4

increases methylation

ISO

Methapyrilene results in increased methylation of TENM4 intron

NCBI chr 1:157,699,611...160,674,549
Ensembl chr 1:159,974,017...160,674,549

G

terminal nucleotidyltransferase 4B

decreases expression

EXP

Methapyrilene results in decreased expression of PAPD5 mRNA

NCBI chr19:34,984,244...35,042,423
Ensembl chr19:34,980,296...35,042,399

G

telomerase reverse transcriptase

increases methylation

ISO

Methapyrilene results in increased methylation of TERT intron

NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111

G

testin LIM domain protein

increases methylation

ISO

Methapyrilene results in increased methylation of TES exon

NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:46,331,257...46,369,780

G

testis expressed 2

increases methylation

ISO

Methapyrilene results in increased methylation of TEX2 intron

NCBI chr10:91,936,390...92,046,360
Ensembl chr10:91,936,390...92,045,944

G

testis expressed 264, ER-phagy receptor

decreases methylation

ISO

Methapyrilene results in decreased methylation of TEX264 promoter

NCBI chr 8:116,174,517...116,201,578
Ensembl chr 8:116,174,518...116,201,667

G

testis expressed 29

decreases methylation

ISO

Methapyrilene results in decreased methylation of TEX29 intron

NCBI chr16:84,352,574...84,366,273
Ensembl chr16:84,352,574...84,366,273

G

transferrin

multiple interactions
decreases expression

ISO
EXP

Methapyrilene inhibits the reaction [HNF4A protein binds to TF promoter]
Methapyrilene results in decreased expression of TF mRNA
Methapyrilene results in decreased expression of TF mRNA; Methapyrilene results in decreased expression of TF protein

PMID:28935588 PMID:30157460

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transcription factor AP-2 gamma

increases methylation

ISO

Methapyrilene results in increased methylation of TFAP2C exon

NCBI chr 3:181,733,524...181,742,412
Ensembl chr 3:181,733,419...181,741,404

G

transcription factor Dp-1

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of TFDP1 intron
Methapyrilene results in decreased expression of TFDP1 mRNA

PMID:30157460 PMID:30467583

NCBI chr16:82,864,220...82,903,166
Ensembl chr16:82,864,226...82,902,996

G

transcription factor Dp-2

decreases methylation

ISO

Methapyrilene results in decreased methylation of TFDP2 intron

NCBI chr 8:105,640,018...105,781,026
Ensembl chr 8:105,640,033...105,781,001

G

transcription factor EB

increases methylation

ISO

Methapyrilene results in increased methylation of TFEB intron

NCBI chr 9:20,696,440...20,752,265
Ensembl chr 9:20,696,441...20,727,863

G

trefoil factor 3

increases methylation

ISO

Methapyrilene results in increased methylation of TFF3 polyA tail

NCBI chr20:9,194,623...9,199,333
Ensembl chr20:9,194,626...9,199,333

G

transferrin receptor 2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of TFR2 mRNA
Methapyrilene results in increased methylation of TFR2 promoter

PMID:28935588 PMID:30157460

NCBI chr12:24,744,450...24,761,413
Ensembl chr12:24,744,450...24,761,413

G

transferrin receptor

increases expression

EXP
ISO

Methapyrilene results in increased expression of TFRC mRNA

PMID:28935588 PMID:30467583

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor alpha

decreases methylation

ISO

Methapyrilene results in decreased methylation of TGFA intron

NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339

G

transforming growth factor, beta 2

increases expression

EXP

Methapyrilene results in increased expression of TGFB2 mRNA

NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856

G

transforming growth factor, beta receptor 2

increases methylation

ISO

Methapyrilene results in increased methylation of TGFBR2 intron

NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469

G

transforming growth factor, beta receptor associated protein 1

increases methylation

ISO

Methapyrilene results in increased methylation of TGFBRAP1 intron

NCBI chr 9:52,813,087...52,863,441
Ensembl chr 9:52,813,087...52,863,441

G

TGFB-induced factor homeobox 2-like, X-linked 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of TGIF2LX exon

NCBI chr X:88,329,744...88,330,830
Ensembl chr X:88,329,783...88,330,828

G

transglutaminase 1

increases methylation

ISO

Methapyrilene results in increased methylation of TGM1 intron

NCBI chr15:33,160,985...33,175,632
Ensembl chr15:33,160,987...33,174,463

G

transglutaminase 2

increases methylation

ISO

Methapyrilene results in increased methylation of TGM2 intron

NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240

G

transglutaminase 4

increases methylation

ISO

Methapyrilene results in increased methylation of TGM4 intron

NCBI chr 8:131,566,887...131,603,920
Ensembl chr 8:131,566,887...131,603,920

G

trans-golgi network protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of TGOLN2 mRNA

NCBI chr 4:106,221,503...106,229,360
Ensembl chr 4:106,221,509...106,229,262

G

thymocyte selection associated family member 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of THEMIS2 intron

NCBI chr 5:150,275,094...150,290,343
Ensembl chr 5:150,275,094...150,290,343

G

threonine synthase-like 2

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of THNSL2 mRNA
Methapyrilene results in increased methylation of THNSL2 promoter

PMID:30157460 PMID:30467583

NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959

G

thyroid hormone responsive

increases expression
decreases expression

EXP
ISO

Methapyrilene results in increased expression of THRSP mRNA
Methapyrilene results in decreased expression of THRSP mRNA

PMID:22484513 PMID:28935588 PMID:30467583 PMID:35690182

NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827

G

thrombospondin type 1 domain containing 4

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of THSD4 polyA tail
Methapyrilene results in increased methylation of THSD4 intron

NCBI chr 8:69,280,397...69,880,144
Ensembl chr 8:69,284,646...69,917,342

G

thrombospondin type 1 domain containing 7A

increases methylation

ISO

Methapyrilene results in increased methylation of THSD7A intron

NCBI chr 4:41,427,276...41,865,524
Ensembl chr 4:41,426,275...41,865,723

G

thiamine triphosphatase

decreases expression

EXP

Methapyrilene results in decreased expression of THTPA mRNA

NCBI chr15:32,536,297...32,541,537
Ensembl chr15:32,537,497...32,541,535

G

TIAM Rac1 associated GEF 1

increases methylation

ISO

Methapyrilene results in increased methylation of TIAM1 intron

NCBI chr11:42,517,527...42,866,280
Ensembl chr11:42,517,528...42,646,075

G

T-cell immunoglobulin and mucin domain containing 4

increases methylation

ISO

Methapyrilene results in increased methylation of TIMD4 exon

NCBI chr10:31,686,994...31,723,095
Ensembl chr10:31,686,862...31,723,077

G

translocase of inner mitochondrial membrane 10B

increases expression

EXP

Methapyrilene results in increased expression of TIMM10B mRNA

PMID:15890375 PMID:28935588

NCBI chr 1:169,392,355...169,395,201
Ensembl chr 1:169,392,177...169,395,205

G

TIMP metallopeptidase inhibitor 1

increases expression

EXP

Methapyrilene results in increased expression of TIMP1 mRNA

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

TIMP metallopeptidase inhibitor 2

increases methylation

ISO

Methapyrilene results in increased methylation of TIMP2 intron

NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214

G

TIMP metallopeptidase inhibitor 3

increases methylation

ISO

Methapyrilene results in increased methylation of TIMP3 intron

NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547

G

TIR domain containing adaptor protein

increases methylation

ISO

Methapyrilene results in increased methylation of TIRAP intron

NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:41,791,878...41,796,312

G

tight junction associated protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TJAP1 exon

NCBI chr 9:22,198,984...22,223,201
Ensembl chr 9:22,199,676...22,223,201

G

tight junction protein 1

affects methylation

ISO

Methapyrilene affects the methylation of TJP1 intron

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

transketolase

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of TKT intron
Methapyrilene results in decreased expression of TKT protein

PMID:30157460 PMID:30467583

NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431

G

TLC domain containing 4

decreases expression

EXP

Methapyrilene results in decreased expression of TLCD4 mRNA

NCBI chr 2:211,969,612...212,044,883
Ensembl chr 2:211,974,471...212,026,081

G

TLE family member 3, transcriptional corepressor

increases methylation

ISO

Methapyrilene results in increased methylation of TLE3 intron

NCBI chr 8:70,753,182...70,799,080
Ensembl chr 8:70,753,383...70,799,074

G

tousled-like kinase 1

decreases expression

EXP

Methapyrilene results in decreased expression of TLK1 mRNA

NCBI chr 3:75,928,303...76,035,246
Ensembl chr 3:75,928,303...76,035,059

G

talin 2

increases methylation

ISO

Methapyrilene results in increased methylation of TLN2 intron

NCBI chr 8:76,712,112...77,133,361
Ensembl chr 8:76,712,112...77,133,361

G

toll-like receptor 5

increases methylation

ISO

Methapyrilene results in increased methylation of TLR5 intron

NCBI chr13:97,166,430...97,190,642
Ensembl chr13:97,166,405...97,192,525

G

transmembrane 4 L six family member 5

increases methylation

ISO

Methapyrilene results in increased methylation of TM4SF5 intron

NCBI chr10:55,718,014...55,724,372
Ensembl chr10:55,717,552...55,724,372

G

transmembrane 7 superfamily member 2

increases expression

EXP

Methapyrilene results in increased expression of TM7SF2 mRNA

NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557

G

transmembrane 9 superfamily member 1

decreases expression

EXP

Methapyrilene results in decreased expression of TM9SF1 mRNA

NCBI chr15:33,097,541...33,108,106
Ensembl chr15:33,097,552...33,105,290

G

transmembrane channel-like 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMC1 intron

NCBI chr 1:227,701,781...227,872,534
Ensembl chr 1:227,701,781...227,872,534

G

transmembrane channel-like 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMC4 intron

NCBI chr 1:74,455,135...74,467,043
Ensembl chr 1:74,454,909...74,467,043

G

transmembrane and coiled-coil domain family 2

increases methylation

ISO

Methapyrilene results in increased methylation of TMCC2 intron

NCBI chr13:46,346,177...46,383,862
Ensembl chr13:46,346,177...46,383,862

G

transmembrane p24 trafficking protein 10

increases methylation

ISO

Methapyrilene results in increased methylation of TMED10 intron

NCBI chr 6:110,722,887...110,757,743
Ensembl chr 6:110,722,889...110,757,777

G

transmembrane protein 106B

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM106B mRNA

NCBI chr 4:42,294,074...42,313,426
Ensembl chr 4:42,294,101...42,313,407

G

transmembrane protein 119

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM119 exon

NCBI chr12:48,489,157...48,496,214
Ensembl chr12:48,489,137...48,496,261

G

transmembrane protein 131

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM131 mRNA

NCBI chr 9:46,512,328...46,658,624
Ensembl chr 9:46,512,328...46,658,481

G

transmembrane protein 132D

affects methylation

ISO

Methapyrilene affects the methylation of TMEM132D intron

NCBI chr12:33,905,971...34,553,267
Ensembl chr12:33,906,644...34,551,317

G

transmembrane protein 147

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM147 mRNA

NCBI chr 1:95,104,448...95,106,268
Ensembl chr 1:95,104,452...95,106,283

G

transmembrane protein 150A

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM150A mRNA

NCBI chr 4:105,968,526...105,972,822
Ensembl chr 4:105,968,702...105,972,822

G

transmembrane protein 161A

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM161A intron

NCBI chr16:19,272,433...19,282,173
Ensembl chr16:19,272,434...19,282,332

G

transmembrane protein 163

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM163 intron

NCBI chr13:41,520,595...41,693,938
Ensembl chr13:41,520,359...41,693,938

G

transmembrane protein 176A

increases expression

EXP

Methapyrilene results in increased expression of TMEM176A mRNA

NCBI chr 4:79,101,946...79,109,499
Ensembl chr 4:79,101,857...79,111,175

G

transmembrane protein 178B

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM178B intron

NCBI chr 4:69,626,188...70,002,400
Ensembl chr 4:69,626,029...70,002,400

G

transmembrane protein 181

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM181 intron

NCBI chr 1:49,235,923...49,290,244
Ensembl chr 1:49,236,025...49,290,616

G

transmembrane protein 184B

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM184B intron

NCBI chr 7:112,805,512...112,848,398
Ensembl chr 7:112,805,512...112,848,351

G

transmembrane protein 184C

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM184C mRNA

NCBI chr19:47,249,403...47,265,502
Ensembl chr19:47,249,500...47,265,949

G

transmembrane protein 201

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM201 intron

NCBI chr 5:165,449,270...165,471,901
Ensembl chr 5:165,449,858...165,471,922

G

transmembrane protein 209

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM209 mRNA

NCBI chr 4:60,070,346...60,096,039
Ensembl chr 4:60,069,060...60,105,946

G

transmembrane protein 210

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM210 promoter

NCBI chr 3:28,498,751...28,499,801
Ensembl chr 3:28,498,751...28,499,801

G

transmembrane protein 221

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM221 polyA tail

NCBI chr16:18,296,036...18,305,077
Ensembl chr16:18,295,931...18,305,246

G

transmembrane protein 233

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM233 intron

NCBI chr12:46,189,247...46,230,434
Ensembl chr12:46,189,236...46,246,891

G

transmembrane protein 238 like

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM238L intron

NCBI chr10:52,148,188...52,161,234
Ensembl chr10:52,149,396...52,149,762

G

transmembrane protein 250

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM250 intron

NCBI chr 3:29,360,770...29,364,756
Ensembl chr 3:29,360,770...29,364,462

G

transmembrane protein 255B

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM255B intron

NCBI chr16:82,759,236...82,810,450
Ensembl chr16:82,774,136...82,808,929

G

transmembrane protein 266

affects methylation

ISO

Methapyrilene affects the methylation of TMEM266 intron

NCBI chr 8:64,603,199...64,716,770
Ensembl chr 8:64,603,186...64,716,769

G

transmembrane protein 270

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM270 intron

NCBI chr12:27,430,092...27,435,243
Ensembl chr12:27,429,985...27,435,242

G

transmembrane protein 30A

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM30A mRNA

NCBI chr 8:89,608,975...89,637,421
Ensembl chr 8:89,608,975...89,633,291

G

transmembrane protein 35A

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM35 intron

NCBI chr X:101,796,623...101,807,471
Ensembl chr X:101,796,623...101,807,470

G

transmembrane protein 38B

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM38B mRNA

NCBI chr 5:73,255,662...73,291,383
Ensembl chr 5:73,255,632...73,292,384

G

transmembrane protein 45b

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM45B intron

NCBI chr 8:38,123,423...38,168,599
Ensembl chr 8:38,123,423...38,168,599

G

transmembrane protein 47

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM47 mRNA

NCBI chr X:49,338,532...49,365,026
Ensembl chr X:49,338,326...49,521,541

G

transmembrane protein 70

decreases expression
multiple interactions

EXP

Methapyrilene results in decreased expression of TMEM70 mRNA
[Diethylnitrosamine co-treated with Methapyrilene] results in decreased expression of TMEM70 protein

NCBI chr 5:7,420,396...7,438,023
Ensembl chr 5:7,420,396...7,438,023

G

transmembrane protein 71

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM71 intron

NCBI chr 7:100,166,038...100,212,234
Ensembl chr 7:100,166,516...100,204,969

G

transmembrane protein 80

decreases expression

EXP

Methapyrilene results in decreased expression of TMEM80 mRNA

NCBI chr 1:205,865,564...205,873,933
Ensembl chr 1:205,864,852...205,873,933

G

transmembrane protein 91

increases methylation

ISO

Methapyrilene results in increased methylation of TMEM91 intron

NCBI chr 1:90,307,264...90,314,796
Ensembl chr 1:90,306,289...90,313,320

G

transmembrane protein 92

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMEM92 intron

NCBI chr10:80,246,205...80,257,650

G

TATA element modulatory factor 1

decreases expression

EXP

Methapyrilene results in decreased expression of TMF1 mRNA

NCBI chr 4:131,316,630...131,345,666
Ensembl chr 4:131,311,801...131,342,436

G

transmembrane inner ear

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMIE intron

NCBI chr 8:119,728,123...119,743,219
Ensembl chr 8:119,728,313...119,743,219

G

tropomodulin 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TMOD1 intron

NCBI chr 5:65,112,062...65,189,563
Ensembl chr 5:65,134,132...65,189,561

G

transmembrane serine protease 11E

increases methylation

ISO

Methapyrilene results in increased methylation of TMPRSS11E intron

NCBI chr14:21,638,418...21,683,029
Ensembl chr14:21,638,418...21,683,029

G

transmembrane serine protease 13

increases methylation

ISO

Methapyrilene results in increased methylation of TMPRSS13 exon

NCBI chr 8:54,522,069...54,550,673
Ensembl chr 8:54,522,443...54,550,670

G

transmembrane serine protease 6

decreases expression

ISO

Methapyrilene results in decreased expression of TMPRSS6 mRNA

NCBI chr 7:111,871,504...111,902,127
Ensembl chr 7:111,871,031...111,902,116

G

thymosin beta 4, X-linked

increases expression

EXP

Methapyrilene results in increased expression of TMSB4X mRNA

NCBI chr X:30,761,611...30,763,612
Ensembl chr X:30,761,612...30,763,613

G

thiol methyltransferase 1A

decreases expression

EXP

Methapyrilene results in decreased expression of TMT1A mRNA

NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:133,330,447...133,338,959

G

transmembrane O-mannosyltransferase targeting cadherins 2

affects methylation

ISO

Methapyrilene affects the methylation of TMTC2 intron

NCBI chr 7:42,280,746...42,695,651
Ensembl chr 7:42,280,746...42,693,350

G

TNF alpha induced protein 3

increases expression

ISO

Methapyrilene results in increased expression of TNFAIP3 mRNA

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979

G

TNF alpha induced protein 8 like 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of TNFAIP8L3 exon

NCBI chr 8:63,309,683...63,351,687
Ensembl chr 8:63,310,107...63,318,501

G

TNF receptor superfamily member 12A

increases expression

EXP

Methapyrilene results in increased expression of TNFRSF12A mRNA

NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704

G

TNF receptor superfamily member 19

increases methylation

ISO

Methapyrilene results in increased methylation of TNFRSF19 intron

NCBI chr15:39,268,305...39,334,566
Ensembl chr15:39,268,305...39,356,438

G

TNF superfamily member 11

increases methylation

ISO

Methapyrilene results in increased methylation of TNFSF11 intron

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479

G

TNF superfamily member 13

decreases expression

EXP

Methapyrilene results in decreased expression of TNFSF13 mRNA

NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815

G

TRAF2 and NCK interacting kinase

increases methylation

ISO

Methapyrilene results in increased methylation of TNIK intron

NCBI chr 2:113,112,937...113,511,341
Ensembl chr 2:113,112,938...113,511,339

G

tenascin N

increases methylation

ISO

Methapyrilene results in increased methylation of TNN exon

NCBI chr13:74,852,586...74,919,789
Ensembl chr13:74,852,586...74,919,789

G

troponin C2, fast skeletal type

increases methylation

ISO

Methapyrilene results in increased methylation of TNNC2 promoter

NCBI chr 3:173,932,611...173,935,339
Ensembl chr 3:173,932,611...173,935,339

G

tenascin R

increases methylation

ISO

Methapyrilene results in increased methylation of TNR intron

NCBI chr13:74,285,141...74,706,174
Ensembl chr13:74,507,366...74,701,115

G

trinucleotide repeat containing 18

affects methylation

ISO

Methapyrilene affects the methylation of TNRC18 intron

NCBI chr12:16,868,930...16,965,224
Ensembl chr12:16,868,978...16,965,217

G

trinucleotide repeat containing adaptor 6A

affects methylation
decreases expression

ISO
EXP

Methapyrilene affects the methylation of TNRC6A intron
Methapyrilene results in decreased expression of TNRC6A mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:186,992,457...187,146,764
Ensembl chr 1:186,992,504...187,146,756

G

trinucleotide repeat containing adaptor 6B

decreases methylation

ISO

Methapyrilene results in decreased methylation of TNRC6B 3' UTR

NCBI chr 7:114,132,574...114,350,010
Ensembl chr 7:114,132,573...114,342,973

G

tensin 1

affects methylation

ISO

Methapyrilene affects the methylation of TNS1 intron

NCBI chr 9:82,941,068...83,152,007
Ensembl chr 9:82,941,068...83,152,007

G

TOG array regulator of axonemal microtubules 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of TOGARAM2 intron

NCBI chr 6:29,491,183...29,549,004
Ensembl chr 6:29,491,040...29,548,977

G

translocase of outer mitochondrial membrane 20

decreases methylation

ISO

Methapyrilene results in decreased methylation of TOMM20 intron

NCBI chr19:71,822,429...71,832,420
Ensembl chr19:71,822,411...71,832,510

G

DNA topoisomerase II alpha

increases expression

EXP

Methapyrilene results in increased expression of TOP2A mRNA; Methapyrilene results in increased expression of TOP2A protein

PMID:15890375 PMID:22584684 PMID:26558467

NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366

G

TOP6B like initiator of meiotic double strand breaks

increases methylation

ISO

Methapyrilene results in increased methylation of TOP6BL intron

NCBI chr 1:211,331,973...211,419,015
Ensembl chr 1:211,331,827...211,419,015

G

testis and ovary specific TOPAZ 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TOPAZ1 intron

NCBI chr 8:131,235,714...131,290,359
Ensembl chr 8:131,236,522...131,290,342

G

torsin 1A interacting protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of TOR1AIP2 mRNA

NCBI chr13:70,775,483...70,806,794
Ensembl chr13:70,780,275...70,806,789
Ensembl chr13:70,780,275...70,806,789

G

torsin family 2, member A

increases methylation

ISO

Methapyrilene results in increased methylation of TOR2A polyA tail

NCBI chr 3:36,446,260...36,450,339
Ensembl chr 3:36,446,273...36,450,908

G

TOX high mobility group box family member 3

affects methylation

ISO

Methapyrilene affects the methylation of TOX3 intron

NCBI chr19:32,820,957...32,929,776
Ensembl chr19:32,820,977...32,929,776

G

tumor protein p53

increases expression

EXP

Methapyrilene results in increased expression of TP53 mRNA

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein p53 inducible nuclear protein 2

decreases expression

EXP

Methapyrilene results in decreased expression of TP53INP2 mRNA

NCBI chr 3:164,341,618...164,350,270
Ensembl chr 3:164,343,205...164,350,225

G

two pore segment channel 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TPCN1 exon

NCBI chr12:41,633,399...41,690,200
Ensembl chr12:41,633,398...41,690,200

G

tumor protein D52

increases expression
decreases expression

ISO

Methapyrilene results in increased expression of TPD52 mRNA
Methapyrilene results in decreased expression of TPD52 mRNA

NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241

G

tryptophan hydroxylase 2

increases methylation

ISO

Methapyrilene results in increased methylation of TPH2 intron

NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:52,571,911...52,675,639

G

thiamin pyrophosphokinase 1

increases methylation

ISO

Methapyrilene results in increased methylation of TPK1 intron

NCBI chr 4:73,170,125...73,557,683
Ensembl chr 4:73,170,125...73,557,783

G

tropomyosin 1

increases expression

EXP

Methapyrilene results in increased expression of TPM1 mRNA

NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468

G

tropomyosin 3

increases expression

EXP

Methapyrilene results in increased expression of TPM3 mRNA

NCBI chr 2:177,812,534...177,842,661
Ensembl chr 2:177,814,883...177,842,660

G

thyroid peroxidase

increases methylation

ISO

Methapyrilene results in increased methylation of TPO polyA tail

NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793

G

translocated promoter region, nuclear basket protein

decreases expression

EXP

Methapyrilene results in decreased expression of TPR mRNA

NCBI chr13:64,974,419...65,037,604
Ensembl chr13:64,974,419...65,037,602

G

tryptase alpha/beta 1

increases methylation

ISO

Methapyrilene results in increased methylation of TPSAB1 polyA tail

NCBI chr10:14,864,887...14,867,302
Ensembl chr10:14,864,887...14,867,302

G

tyrosylprotein sulfotransferase 1

decreases expression

EXP

Methapyrilene results in decreased expression of TPST1 mRNA

NCBI chr12:32,180,688...32,247,478
Ensembl chr12:32,180,936...32,241,821

G

TraB domain containing 2B

increases methylation

ISO

Methapyrilene results in increased methylation of TRABD2B intron

NCBI chr 5:133,178,014...133,395,740
Ensembl chr 5:133,178,302...133,441,812

G

tetratricopeptide repeat and ankyrin repeat containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of TRANK1 intron

NCBI chr 8:120,153,381...120,233,879
Ensembl chr 8:120,154,362...120,234,087

G

TNF receptor-associated protein 1

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of TRAP1 mRNA; Methapyrilene results in decreased expression of TRAP1 protein
Methapyrilene results in increased methylation of TRAP1 intron

PMID:30157460 PMID:30467583

NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,970,995...12,005,355

G

trafficking protein particle complex subunit 12

increases methylation

ISO

Methapyrilene results in increased methylation of TRAPPC12 intron

NCBI chr 6:51,049,878...51,115,343
Ensembl chr 6:51,049,878...51,115,297

G

trafficking protein particle complex subunit 6A

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRAPPC6A intron

NCBI chr 1:88,286,533...88,293,493
Ensembl chr 1:88,286,362...88,293,493

G

trafficking protein particle complex subunit 9

affects methylation

ISO

Methapyrilene affects the methylation of TRAPPC9 intron

NCBI chr 7:106,410,339...106,887,364
Ensembl chr 7:106,410,339...106,887,363

G

trafficking regulator of GLUT4 (SLC2A4) 1

increases methylation

ISO

Methapyrilene results in increased methylation of TRARG1 intron

NCBI chr10:62,019,281...62,039,666
Ensembl chr10:62,019,189...62,039,648

G

tRNA aspartic acid methyltransferase 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRDMT1 intron

NCBI chr17:81,510,740...81,554,036
Ensembl chr17:81,521,200...81,577,639

G

triadin

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRDN intron

NCBI chr 1:25,774,765...26,230,069
Ensembl chr 1:25,774,765...26,229,717

G

transcriptional regulating factor 1

increases methylation

ISO

Methapyrilene results in increased methylation of TRERF1 intron

NCBI chr 9:21,131,772...21,355,830
Ensembl chr 9:21,131,777...21,176,016

G

thyrotropin releasing hormone

increases methylation

ISO

Methapyrilene results in increased methylation of TRH exon

NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:126,299,236...126,301,762

G

thyrotropin-releasing hormone degrading enzyme

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRHDE intron

NCBI chr 7:51,829,473...52,236,843
Ensembl chr 7:51,832,111...52,236,843

G

tribbles pseudokinase 3

increases expression

EXP

Methapyrilene results in increased expression of TRIB3 mRNA

NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802

G

tripartite motif-containing 14

decreases expression

EXP

Methapyrilene results in decreased expression of TRIM14 mRNA

NCBI chr 5:65,596,149...65,620,434
Ensembl chr 5:65,596,149...65,620,434

G

tripartite motif-containing 2

decreases expression

EXP

Methapyrilene results in decreased expression of TRIM2 mRNA

NCBI chr 2:171,798,654...171,950,193
Ensembl chr 2:171,798,660...171,913,468

G

tripartite motif-containing 29

increases methylation

ISO

Methapyrilene results in increased methylation of TRIM29 intron

NCBI chr 8:52,579,175...52,603,919
Ensembl chr 8:52,579,175...52,603,919

G

tripartite motif-containing 44

increases methylation

ISO

Methapyrilene results in increased methylation of TRIM44 intron

NCBI chr 3:109,048,643...109,183,821
Ensembl chr 3:109,048,643...109,183,821

G

tripartite motif-containing 5

decreases expression

EXP

Methapyrilene results in decreased expression of TRIM5 mRNA

NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:168,132,308...168,141,657

G

tripartite motif-containing 62

increases methylation

ISO

Methapyrilene results in increased methylation of TRIM62 intron

NCBI chr 5:146,516,349...146,545,015
Ensembl chr 5:146,515,090...146,545,015

G

tripartite motif-containing 66

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRIM66 exon

NCBI chr 1:172,903,771...172,974,475
Ensembl chr 1:172,799,348...172,974,801

G

tripartite motif containing 71

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRIM71 intron

NCBI chr 8:123,076,499...123,129,016

G

tripartite motif-containing 8

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRIM8 intron

NCBI chr 1:255,311,039...255,325,937
Ensembl chr 1:255,310,457...255,325,937

G

trio Rho guanine nucleotide exchange factor

affects methylation

ISO

Methapyrilene affects the methylation of TRIO intron

NCBI chr 2:80,235,485...80,531,824
Ensembl chr 2:80,235,485...80,531,612

G

thyroid hormone receptor interactor 12

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRIP12 intron

NCBI chr 9:93,364,791...93,491,015
Ensembl chr 9:93,364,791...93,490,159

G

tRNA methyltransferase 12

decreases expression

EXP

Methapyrilene results in decreased expression of TRMT12 mRNA

NCBI chr 7:92,307,319...92,308,945
Ensembl chr 7:92,307,266...92,309,346

G

tRNA methyltransferase 2 homolog B

increases methylation

ISO

Methapyrilene results in increased methylation of TRMT2B intron

NCBI chr X:101,716,656...101,777,105

G

TMF1-regulated nuclear protein 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TRNP1 intron

NCBI chr 5:150,990,312...150,997,148
Ensembl chr 5:150,989,973...150,997,277

G

transient receptor potential cation channel, subfamily M, member 1

increases methylation

ISO

Methapyrilene results in increased methylation of TRPM1 intron

NCBI chr 1:127,130,686...127,247,219
Ensembl chr 1:127,130,686...127,247,391

G

transient receptor potential cation channel, subfamily M, member 4

increases methylation

ISO

Methapyrilene results in increased methylation of TRPM4 intron

NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:104,918,462...104,948,653

G

tRNA phosphotransferase 1

increases methylation

ISO

Methapyrilene results in increased methylation of TRPT1 polyA tail

NCBI chr 1:213,615,503...213,620,502
Ensembl chr 1:213,614,135...213,620,502

G

transient receptor potential cation channel, subfamily V, member 1

increases methylation

ISO

Methapyrilene results in increased methylation of TRPV1 intron

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021

G

transient receptor potential cation channel, subfamily V, member 3

increases methylation

ISO

Methapyrilene results in increased methylation of TRPV3 intron

NCBI chr10:58,382,054...58,413,657
Ensembl chr10:58,382,054...58,411,800

G

TSC22 domain family, member 1

decreases expression
increases methylation

EXP
ISO

Methapyrilene results in decreased expression of TSC22D1 mRNA
Methapyrilene results in increased methylation of TSC22D1 intron

PMID:15089088 PMID:15890375 PMID:30157460

NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322

G

testis specific 10

decreases methylation

ISO

Methapyrilene results in decreased methylation of TSGA10 intron

NCBI chr 9:47,487,007...47,594,201
Ensembl chr 9:47,487,007...47,593,980

G

teashirt zinc finger homeobox 1

decreases expression

EXP

Methapyrilene results in decreased expression of TSHZ1 mRNA

NCBI chr18:79,651,256...79,727,662
Ensembl chr18:79,651,256...79,727,662

G

teashirt zinc finger homeobox 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of TSHZ2 intron

NCBI chr 3:178,824,221...179,271,151
Ensembl chr 3:178,824,994...179,269,641

G

teashirt zinc finger homeobox 3

increases methylation

ISO

Methapyrilene results in increased methylation of TSHZ3 polyA tail

NCBI chr 1:98,525,584...98,597,428
Ensembl chr 1:98,518,681...98,598,007

G

tsukushi, small leucine rich proteoglycan

decreases expression

EXP

Methapyrilene results in decreased expression of TSKU mRNA

NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272

G

translin

decreases expression

EXP

Methapyrilene results in decreased expression of TSN mRNA

NCBI chr13:31,917,133...31,930,069
Ensembl chr13:31,919,231...31,930,417

G

t-SNARE domain containing 1

increases methylation
affects methylation

ISO

Methapyrilene results in increased methylation of TSNARE1 3' UTR
Methapyrilene affects the methylation of TSNARE1 intron

NCBI chr 7:108,115,051...108,296,299

G

tetraspanin 10

decreases methylation

ISO

Methapyrilene results in decreased methylation of TSPAN10 intron

NCBI chr10:106,213,672...106,219,951
Ensembl chr10:106,214,208...106,219,085

G

tetraspanin 18

decreases methylation

ISO

Methapyrilene results in decreased methylation of TSPAN18 intron

NCBI chr 3:99,615,465...99,755,270
Ensembl chr 3:99,615,466...99,755,270

G

tetraspanin 4

increases methylation

ISO

Methapyrilene results in increased methylation of TSPAN4 3' UTR

NCBI chr 1:206,001,731...206,021,414
Ensembl chr 1:206,001,731...206,021,413

G

tetraspanin 8

increases methylation

ISO

Methapyrilene results in increased methylation of TSPAN8 intron

NCBI chr 7:53,331,019...53,365,402
Ensembl chr 7:53,330,963...53,365,401

G

tetraspanin 9

affects methylation
increases methylation

ISO

Methapyrilene affects the methylation of TSPAN9 3' UTR
Methapyrilene results in increased methylation of TSPAN9 intron

NCBI chr 4:162,500,029...162,681,699
Ensembl chr 4:162,500,029...162,574,208

G

thrombospondin-type laminin G domain and EAR repeats

increases methylation

ISO

Methapyrilene results in increased methylation of TSPEAR intron

NCBI chr20:10,771,365...10,944,285
Ensembl chr20:10,771,371...10,943,708

G

TSPY-like 1

decreases expression

EXP

Methapyrilene results in decreased expression of TSPYL1 mRNA

NCBI chr20:39,637,035...39,639,594
Ensembl chr20:39,635,135...39,695,333

G

tumor suppressing subtransferable candidate 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of TSSC4 intron

NCBI chr 1:207,681,420...207,684,244
Ensembl chr 1:207,682,322...207,685,485

G

thiosulfate sulfurtransferase

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of TST polyA tail
Methapyrilene results in decreased expression of TST mRNA

PMID:30157460 PMID:30467583

NCBI chr 7:111,828,557...111,836,980
Ensembl chr 7:111,828,558...111,837,116

G

tau tubulin kinase 1

decreases methylation
increases methylation

ISO

Methapyrilene results in decreased methylation of TTBK1 3' UTR
Methapyrilene results in increased methylation of TTBK1 exon

NCBI chr 9:21,990,973...22,035,961
Ensembl chr 9:21,990,973...22,035,961

G

tau tubulin kinase 2

increases methylation

ISO

Methapyrilene results in increased methylation of TTBK2 exon

NCBI chr 3:128,144,851...128,256,630
Ensembl chr 3:128,144,851...128,258,738

G

tetratricopeptide repeat domain 13

decreases expression

EXP

Methapyrilene results in decreased expression of TTC13 mRNA

NCBI chr19:69,534,989...69,589,590
Ensembl chr19:69,534,989...69,589,563

G

tetratricopeptide repeat domain 17

decreases expression

EXP

Methapyrilene results in decreased expression of TTC17 mRNA

NCBI chr 3:100,718,820...100,829,464
Ensembl chr 3:100,718,827...100,829,129

G

tetratricopeptide repeat domain 23

increases methylation
decreases expression

ISO
EXP

Methapyrilene results in increased methylation of TTC23 intron
Methapyrilene results in decreased expression of TTC23 mRNA

PMID:30157460 PMID:30467583

NCBI chr 1:130,656,040...130,739,670
Ensembl chr 1:130,656,110...130,739,673

G

tetratricopeptide repeat domain 24

increases methylation

ISO

Methapyrilene results in increased methylation of TTC24 polyA tail

NCBI chr 2:175,818,921...175,830,991
Ensembl chr 2:175,822,898...175,828,016

G

tetratricopeptide repeat domain 28

decreases methylation

ISO

Methapyrilene results in decreased methylation of TTC28 intron

NCBI chr12:51,002,816...51,443,461
Ensembl chr12:51,005,089...51,443,531

G

tetratricopeptide repeat domain 34

increases methylation

ISO

Methapyrilene results in increased methylation of TTC34 exon

NCBI chr 5:170,693,410...170,711,215
Ensembl chr 5:170,693,402...170,710,368

G

tetratricopeptide repeat domain 36

decreases expression

EXP

Methapyrilene results in decreased expression of TTC36 mRNA

NCBI chr 8:54,009,522...54,013,129
Ensembl chr 8:54,009,522...54,013,129

G

tetratricopeptide repeat domain 38

increases methylation

ISO

Methapyrilene results in increased methylation of TTC38 intron

NCBI chr 7:118,805,115...118,828,449
Ensembl chr 7:118,804,047...118,828,453

G

tetratricopeptide repeat domain 4

decreases methylation

ISO

Methapyrilene results in decreased methylation of TTC4 intron

NCBI chr 5:126,673,535...126,691,203
Ensembl chr 5:126,673,535...126,691,277

G

tetratricopeptide repeat domain 6

increases methylation

ISO

Methapyrilene results in increased methylation of TTC6 intron

NCBI chr 6:80,872,055...81,103,170
Ensembl chr 6:80,889,487...81,103,163

G

tubulin tyrosine ligase like 5

increases methylation

ISO

Methapyrilene results in increased methylation of TTLL5 intron

NCBI chr 6:111,214,048...111,431,892
Ensembl chr 6:111,214,103...111,431,891

G

tubulin tyrosine ligase like 6

affects methylation

ISO

Methapyrilene affects the methylation of TTLL6 intron

NCBI chr10:81,579,110...81,623,917
Ensembl chr10:81,579,178...81,623,919

G

tubulin tyrosine ligase like 8

increases methylation

ISO

Methapyrilene results in increased methylation of TTLL8 intron

NCBI chr 7:121,860,192...121,926,344
Ensembl chr 7:121,882,458...121,924,726

G

alpha tocopherol transfer protein

decreases expression

EXP

Methapyrilene results in decreased expression of TTPA mRNA

NCBI chr 5:38,294,415...38,315,471
Ensembl chr 5:38,292,665...38,315,804

G

tweety family member 1

decreases methylation

ISO

Methapyrilene results in decreased methylation of TTYH1 intron

NCBI chr 1:79,125,564...79,144,137
Ensembl chr 1:79,125,574...79,144,091

G

tweety family member 2

increases methylation

ISO

Methapyrilene results in increased methylation of TTYH2 intron

NCBI chr10:100,208,129...100,252,505
Ensembl chr10:100,207,860...100,253,521

G

tubulin, alpha 1C

increases expression

EXP

Methapyrilene results in increased expression of TUBA1C mRNA

NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311

G

tubulin, alpha 4A

increases expression

EXP

Methapyrilene results in increased expression of TUBA4A mRNA

NCBI chr 9:84,158,871...84,174,041
Ensembl chr 9:84,158,280...84,162,584

G

tubulin, beta 2A class IIa

increases expression

EXP

Methapyrilene results in increased expression of TUBB2A mRNA

NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,983,387...31,006,838

G

tubulin, beta 4B class IVb

increases expression

EXP

Methapyrilene results in increased expression of TUBB4B mRNA

NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:28,435,148...28,439,719

G

tubulin, beta 5 class I

increases expression

EXP

Methapyrilene results in increased expression of TUBB5 mRNA

PMID:15120968 PMID:15890375 PMID:22584684 PMID:30467583

NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726

G

tubulin, beta 6 class V

increases expression

EXP

Methapyrilene results in increased expression of TUBB6 mRNA

NCBI chr18:63,213,287...63,222,926
Ensembl chr18:63,213,279...63,224,303

G

tubulin gamma complex component 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of TUBGCP3 polyA tail

NCBI chr16:83,553,950...83,614,626
Ensembl chr16:83,553,959...83,614,623

G

tumor suppressor candidate 3

increases methylation

ISO

Methapyrilene results in increased methylation of TUSC3 promoter

NCBI chr16:59,899,642...60,048,813
Ensembl chr16:59,899,091...60,048,215

G

terminal uridylyl transferase 4

decreases expression

EXP

Methapyrilene results in decreased expression of TUT4 mRNA

NCBI chr 5:128,354,975...128,535,288
Ensembl chr 5:128,431,719...128,535,656

G

terminal uridylyl transferase 7

decreases expression

EXP

Methapyrilene results in decreased expression of ZCCHC6 mRNA

NCBI chr17:4,854,553...4,908,758
Ensembl chr17:4,855,936...4,909,070

G

twisted gastrulation BMP signaling modulator 1

decreases expression

EXP

Methapyrilene results in decreased expression of TWSG1 mRNA

NCBI chr 9:112,979,972...113,014,315
Ensembl chr 9:112,979,972...113,014,315

G

TXK tyrosine kinase

increases expression

EXP

Methapyrilene results in increased expression of TXK mRNA

NCBI chr14:35,817,270...35,873,454
Ensembl chr14:35,817,893...35,873,460

G

thioredoxin interacting protein

decreases expression

EXP

Methapyrilene results in decreased expression of TXNIP mRNA

NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731

G

thioredoxin-like 4B

increases expression

EXP

Methapyrilene results in increased expression of TXNL4B mRNA

NCBI chr19:54,439,686...54,449,777
Ensembl chr19:54,439,680...54,448,052

G

thioredoxin reductase 1

increases expression

EXP

Methapyrilene results in increased expression of TXNRD1 mRNA

PMID:16393664 PMID:28935588

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817

G

thioredoxin reductase 2

increases methylation

ISO

Methapyrilene results in increased methylation of TXNRD2 intron; Methapyrilene results in increased methylation of TXNRD2 promoter

NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475

G

thymidylate synthetase

increases expression

EXP

Methapyrilene results in increased expression of TYMS mRNA

NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097

G

trypsin like peroxisomal matrix peptidase 1

decreases expression

EXP

Methapyrilene results in decreased expression of TYSND1 mRNA

NCBI chr20:30,180,878...30,188,239
Ensembl chr20:30,181,090...30,188,236

G

U2 snRNP-associated SURP domain containing

decreases expression

EXP

Methapyrilene results in decreased expression of U2SURP mRNA

NCBI chr 8:104,898,580...104,963,642
Ensembl chr 8:104,898,425...104,955,422

G

ubiquitin-like modifier activating enzyme 6

decreases expression

EXP

Methapyrilene results in decreased expression of UBA6 mRNA

NCBI chr14:22,238,832...22,302,650
Ensembl chr14:22,211,601...22,302,650

G

ubiquitin associated protein 2-like

decreases methylation

ISO

Methapyrilene results in decreased methylation of UBAP2L exon

NCBI chr 2:177,736,378...177,791,746
Ensembl chr 2:177,736,696...177,791,646

G

ubiquitin-conjugating enzyme E2C

increases expression

EXP

Methapyrilene results in increased expression of UBE2C mRNA

PMID:22484513 PMID:22584684

NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678

G

ubiquitin-conjugating enzyme E2D 2

decreases methylation

ISO

Methapyrilene results in decreased methylation of UBE2D2 intron

NCBI chr18:27,638,399...27,680,386
Ensembl chr18:27,638,527...27,683,074

G

ubiquitin-conjugating enzyme E2L 3

decreases methylation

ISO

Methapyrilene results in decreased methylation of UBE2L3 intron

NCBI chr11:97,300,584...97,343,084
Ensembl chr11:97,301,945...97,343,084

G

ubiquitin-conjugating enzyme E2N

increases expression

EXP

Methapyrilene results in increased expression of UBE2N mRNA

NCBI chr 7:32,041,190...32,071,252

G

ubiquitin conjugating enzyme E2 QL1

increases methylation

ISO

Methapyrilene results in increased methylation of UBE2QL1 intron

NCBI chr 1:35,377,264...35,417,624

G

ubiquitin-conjugating enzyme E2T

increases expression

EXP

Methapyrilene results in increased expression of UBE2T mRNA

NCBI chr13:48,955,166...48,965,668
Ensembl chr13:48,955,183...48,966,646

G

ubiquitin protein ligase E3A

decreases methylation

ISO

Methapyrilene results in decreased methylation of UBE3A intron

NCBI chr 1:119,204,244...119,297,097
Ensembl chr 1:119,206,148...119,297,097

G

ubiquitin protein ligase E3D

increases methylation

ISO

Methapyrilene results in increased methylation of UBE3D intron

NCBI chr 8:96,125,609...96,293,122
Ensembl chr 8:95,882,167...96,293,078

G

ubiquitination factor E4A

decreases expression

EXP

Methapyrilene results in decreased expression of UBE4A mRNA

NCBI chr 8:54,132,799...54,174,921
Ensembl chr 8:54,132,801...54,174,835

G

ubiquitination factor E4B

decreases methylation

ISO

Methapyrilene results in decreased methylation of UBE4B intron

NCBI chr 5:165,049,897...165,153,572
Ensembl chr 5:165,049,897...165,153,572

G

ubiquilin 2

decreases expression

EXP

Methapyrilene results in decreased expression of UBQLN2 mRNA

NCBI chr X:21,228,809...21,232,228
Ensembl chr X:21,229,197...21,232,268

G

ubiquitin protein ligase E3 component n-recognin 1

decreases methylation
decreases expression

ISO
EXP

Methapyrilene results in decreased methylation of UBR1 intron
Methapyrilene results in decreased expression of UBR1 mRNA

PMID:30157460 PMID:30467583

NCBI chr 3:128,265,160...128,377,830
Ensembl chr 3:128,265,115...128,375,671

G

ubiquitin domain containing 1

increases methylation

ISO

Methapyrilene results in increased methylation of UBTD1 intron