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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bleomycin A2
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Accession:CHEBI:3139 term browser browse the term
Definition:A bleomycin that has formula C55H84N17O21S3.
Synonyms:exact_synonym: (betaR)-N(alpha)-{[6-amino-2-((1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl)-5-methylpyrimidin-4-yl]carbonyl}-beta-{2-O-[3-O-(aminocarbonyl)-alpha-D-mannopyranosyl]-alpha-L-gulopyranosyloxy}-N-[(1R,2S,3S)-5-({(1S,2R)-1-[({2-[4-({[3-(dimethylsulfonio)propyl]amino}carbonyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)carbonyl]-2-hydroxypropyl}amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl]-L-histidinamide
 related_synonym: Bleomycin;   Formula=C55H84N17O21S3;   InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-/m0/s1;   InChIKey=OYVAGSVQBOHSSS-UAPAGMARSA-O;   N(1)-[3-(dimethylsulfonio)propyl]bleomycinamide;   SMILES=[H][C@](C)(NC(=O)[C@@]([H])(NC(=O)c1nc(nc(N)c1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@]([H])(O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1c[nH]cn1)[C@@H](O)[C@H](C)C(=O)N[C@]([H])(C(=O)NCCc1nc(cs1)-c1nc(cs1)C(=O)NCCC[S+](C)C)[C@@]([H])(C)O
 alt_id: CHEBI:165316;   CHEBI:357107;   CHEBI:41102;   CHEBI:653800
 xref: Beilstein:4379083;   CAS:11056-06-7;   CAS:11116-31-7;   Gmelin:1667354;   KEGG:C06854;   KEGG:C15773;   KEGG:D07535;   KNApSAcK:C00018738
 xref_mesh: MESH:D001761
 xref: PDBeChem:BLM;   PMID:12477361;   Wikipedia:Bleomycin


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bleomycin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 decreases expression EXP Bleomycin results in decreased expression of ABCA3 mRNA; Bleomycin results in decreased expression of ABCA3 protein CTD PMID:34425168 NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
decreases expression 		EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] CTD PMID:20581171 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions
decreases expression 		EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] CTD PMID:20581171 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; celastrol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
Bleomycin results in decreased expression of ACTA2 protein
Ephedrine inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] 		CTD PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 More... NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Actg1 actin, gamma 1 increases expression ISO Bleomycin results in increased expression of ACTG1 mRNA CTD PMID:36087614 NCBI chr10:106,118,106...106,120,951
Ensembl chr10:106,118,108...106,120,951 		JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Bleomycin results in decreased expression of ACTN1 protein CTD PMID:25933445 NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172 		JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP Bleomycin results in decreased expression of ACTN4 protein CTD PMID:25933445 NCBI chr 1:93,310,294...93,379,369
Ensembl chr 1:93,310,278...93,379,320 		JBrowse link
G Actr10 actin related protein 10 increases expression ISO Bleomycin results in increased expression of ACTR10 mRNA CTD PMID:36087614 NCBI chr 6:95,182,082...95,208,325
Ensembl chr 6:95,182,111...95,209,021 		JBrowse link
G Actr3b actin related protein 3B increases expression ISO Bleomycin results in increased expression of ACTR3B mRNA CTD PMID:36087614 NCBI chr 4:9,995,553...10,089,422
Ensembl chr 4:9,996,155...10,089,553 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ADAM17 protein CTD PMID:22687607 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344 		JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP Bleomycin results in decreased expression of ADRA1B mRNA CTD PMID:15808516 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression 		EXP protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] CTD PMID:25582705 PMID:25933445 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression 		EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] CTD PMID:20581171 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression EXP Bleomycin results in increased expression of AHSG protein CTD PMID:25933445 NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]; Bleomycin affects the expression of and affects the localization of AIFM1 protein; Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein] CTD PMID:37783230 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607 PMID:26520185 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin increases expression EXP Bleomycin results in increased expression of ALB protein CTD PMID:25933445 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Bleomycin results in decreased expression of ALDH1A1 protein CTD PMID:25933445 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein CTD PMID:29733421 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133 		JBrowse link
G Angptl3 angiopoietin-like 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of ANGPTL3 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ANGPTL3 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ANGPTL3 protein] 		CTD PMID:30825431 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Bleomycin results in increased expression of ANKRD1 mRNA CTD PMID:26345256 NCBI chr 1:243,228,460...243,237,014
Ensembl chr 1:243,228,448...243,263,751 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP Bleomycin results in increased expression of ANP32E protein CTD PMID:25933445 NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986 		JBrowse link
G Anxa2 annexin A2 decreases expression EXP Bleomycin results in decreased expression of ANXA2 protein CTD PMID:25933445 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631 		JBrowse link
G Anxa3 annexin A3 decreases expression EXP Bleomycin results in decreased expression of ANXA3 protein CTD PMID:25933445 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849 		JBrowse link
G Anxa4 annexin A4 decreases expression EXP Bleomycin results in decreased expression of ANXA4 protein CTD PMID:25933445 NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513 		JBrowse link
G Anxa5 annexin A5 increases expression EXP Bleomycin results in increased expression of ANXA5 protein CTD PMID:25933445 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400 		JBrowse link
G Anxa6 annexin A6 decreases expression EXP Bleomycin results in decreased expression of ANXA6 protein CTD PMID:25933445 NCBI chr10:39,602,106...39,657,183
Ensembl chr10:39,602,106...39,657,359 		JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891 		JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Bleomycin results in decreased expression of AQP1 mRNA CTD PMID:15782499 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504 		JBrowse link
G Areg amphiregulin increases expression ISO Bleomycin results in increased expression of AREG mRNA CTD PMID:26817844 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Arg1 arginase 1 increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein
Bleomycin results in decreased expression of ARG1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ARG1 protein] 		CTD PMID:26345256 PMID:26526764 PMID:30825431 PMID:33647319 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression 		EXP pachymic acid inhibits the reaction [Bleomycin results in increased expression of ATF4 protein] CTD PMID:37163307 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation 		ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] CTD PMID:24933654 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Bleomycin results in decreased expression of ATP5F1B protein CTD PMID:25933445 NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Bleomycin results in increased expression of ATP5IF1 protein CTD PMID:25933445 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677 		JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:1,464,788...1,465,989
Ensembl chr14:1,464,800...1,465,988 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Bleomycin results in decreased expression of ATP5PO protein CTD PMID:29733421 NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression 		ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Bleomycin results in decreased expression of ATP6V1A protein 		CTD PMID:29733421 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Bleomycin results in decreased expression of AVPR1A mRNA CTD PMID:15808516 NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP Bleomycin results in increased expression of BASP1 protein CTD PMID:25933445 NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:77,546,092...77,597,178 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		EXP
ISO 		allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]
Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein] 		CTD PMID:23656969 PMID:26093215 PMID:32278510 PMID:37783230 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression 		EXP
ISO 		[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA]
[Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]; Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein] 		CTD PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression 		ISO thymoquinone inhibits the reaction [Bleomycin results in decreased expression of BCL2L1 mRNA] CTD PMID:34818114 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631 		JBrowse link
G Bik BCL2-interacting killer increases expression ISO Bleomycin results in increased expression of BIK mRNA CTD PMID:36087614 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance
increases expression 		ISO
EXP 		BIRC2 protein results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of BIRC2 protein 		CTD PMID:10815900 PMID:15371238 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Bleomycin results in increased expression of BIRC5 mRNA CTD PMID:26345256 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Blmh bleomycin hydrolase affects response to substance ISO BLMH gene polymorphism affects the susceptibility to Bleomycin CTD PMID:12082022 NCBI chr10:62,270,170...62,313,349
Ensembl chr10:62,270,033...62,313,345 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Bleomycin results in decreased expression of BMP7 mRNA CTD PMID:29408570 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Bleomycin results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:215,160,764...215,172,540
Ensembl chr 1:215,160,957...215,172,536 		JBrowse link
G C1qb complement C1q B chain increases expression ISO Bleomycin results in increased expression of C1QB mRNA CTD PMID:26345256 NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840 		JBrowse link
G Ca1 carbonic anhydrase 1 decreases expression EXP Bleomycin results in decreased expression of CA1 protein CTD PMID:25933445 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO Bleomycin results in increased expression of CALCA mRNA CTD PMID:36087614 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Cald1 caldesmon 1 increases expression EXP Bleomycin results in increased expression of CALD1 protein CTD PMID:25933445 NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression EXP Bleomycin results in decreased expression of CALML3 protein CTD PMID:25933445 NCBI chr17:71,329,438...71,333,068
Ensembl chr17:71,319,943...71,335,682 		JBrowse link
G Calr calreticulin increases expression EXP Bleomycin results in increased expression of CALR protein CTD PMID:25933445 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236 		JBrowse link
G Calu calumenin increases expression EXP Bleomycin results in increased expression of CALU protein CTD PMID:25933445 NCBI chr 4:58,914,456...58,941,957
Ensembl chr 4:58,914,421...58,941,956 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Bleomycin results in decreased expression of CA2 protein CTD PMID:25933445 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 increases expression EXP Bleomycin results in increased expression of CARHSP1 protein CTD PMID:25933445 NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
increases cleavage 		EXP
ISO 		[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA]
Bleomycin results in increased activity of CASP3 protein
Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]]; baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein] 		CTD PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression 		EXP
ISO 		Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein; pachymic acid inhibits the reaction [Bleomycin results in increased expression of CASP9 protein]
Bleomycin results in increased activity of CASP9 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA 		CTD PMID:15371238 PMID:22687607 PMID:26800624 PMID:37163307 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cast calpastatin increases expression EXP Bleomycin results in increased expression of CAST protein CTD PMID:25933445 NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:5,707,640...5,817,180 		JBrowse link
G Cat catalase increases response to substance
multiple interactions
increases expression
decreases activity 		ISO
EXP 		CAT protein results in increased susceptibility to Bleomycin
Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; Oils, Volatile inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
Bleomycin results in increased expression of CAT protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]
celastrol inhibits the reaction [Bleomycin results in decreased activity of CAT protein]; pachymic acid inhibits the reaction [Bleomycin results in decreased activity of CAT protein] 		CTD PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 PMID:28850077 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 decreases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of CAV1 protein
Bleomycin results in decreased expression of CAV1 mRNA; Bleomycin results in decreased expression of CAV1 protein
yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 protein] 		CTD PMID:25933445 PMID:37898439 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression EXP Bleomycin results in decreased expression of CAVIN2 protein CTD PMID:25933445 NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024 		JBrowse link
G Cbx8 chromobox 8 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of CBX8 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA] 		CTD PMID:30825431 NCBI chr10:104,793,062...104,795,500
Ensembl chr10:104,793,062...104,795,500 		JBrowse link
G Cckar cholecystokinin A receptor decreases expression EXP Bleomycin results in decreased expression of CCKAR mRNA CTD PMID:15808516 NCBI chr14:61,505,270...61,513,618
Ensembl chr14:61,505,270...61,513,618 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
decreases response to substance
multiple interactions
decreases expression 		ISO Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein
CCL11 gene mutant form results in decreased susceptibility to Bleomycin
CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
Bleomycin results in decreased expression of CCL11 mRNA 		CTD PMID:16314464 PMID:29720568 NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression
multiple interactions
decreases expression 		ISO Bleomycin results in increased expression of CCL12 mRNA
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA]
Bleomycin results in decreased expression of CCL12 mRNA 		CTD PMID:28434932 PMID:29720568 NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,567,876...67,569,426 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein CTD PMID:26345256 PMID:29175452 NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]
Bleomycin results in decreased expression of CCL2 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CCL2 protein 		CTD PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 More... NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of CCL3 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA]
Bleomycin results in decreased expression of CCL3 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] affects the expression of CCL3 protein
Bleomycin results in decreased expression of CCL3 protein 		CTD PMID:26520185 PMID:29720568 PMID:32828905 PMID:33516805 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Bleomycin results in decreased expression of CCL4 mRNA CTD PMID:29720568 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CCL5 mRNA
SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA] 		CTD PMID:32828905 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Bleomycin results in decreased expression of CCL7 mRNA CTD PMID:29720568 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CCL6 protein CTD PMID:29175452 NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression 		ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; bufotalin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]
Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein 		CTD PMID:19080365 PMID:26817844 PMID:27153807 PMID:28434932 PMID:32032644 More... NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccng1 cyclin G1 increases expression ISO Bleomycin results in increased expression of CCNG1 mRNA CTD PMID:26345256 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases response to substance
increases expression 		ISO CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
CCR2 gene mutant form results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of CCR2 mRNA 		CTD PMID:14609568 PMID:29033951 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein CTD PMID:16314464 NCBI chr 8:132,463,533...132,511,601
Ensembl chr 8:132,463,788...132,511,593 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 affects expression
increases expression
multiple interactions 		ISO Bleomycin affects the expression of CCR5 mRNA
Bleomycin results in increased expression of CCR5 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA] 		CTD PMID:26345256 PMID:30825431 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Bleomycin results in increased expression of CD14 mRNA CTD PMID:36087614 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd2 Cd2 molecule increases expression ISO Bleomycin results in increased expression of CD2 mRNA CTD PMID:36087614 NCBI chr 2:191,399,510...191,412,659
Ensembl chr 2:191,399,510...191,413,665 		JBrowse link
G Cd33 CD33 molecule increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CD33 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA] 		CTD PMID:30825431 NCBI chr 1:103,071,985...103,086,687
Ensembl chr 1:103,072,375...103,086,291 		JBrowse link
G Cd34 CD34 molecule multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CD34 protein] CTD PMID:30825431 NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315 		JBrowse link
G Cd36 CD36 molecule decreases expression ISO Bleomycin results in decreased expression of CD36 mRNA CTD PMID:29408570 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd44 CD44 molecule multiple interactions
increases expression 		ISO honokiol inhibits the reaction [Bleomycin results in increased expression of CD44 protein] CTD PMID:32032644 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Bleomycin results in increased expression of CD83 mRNA CTD PMID:36087614 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047 		JBrowse link
G Cd86 CD86 molecule decreases expression ISO Bleomycin results in decreased expression of CD86 mRNA CTD PMID:29720568 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Bleomycin results in increased expression of CDC20 mRNA CTD PMID:26345256 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression 		ISO
EXP 		12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; honokiol inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; pirfenidone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]
Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein
Ephedrine inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein] 		CTD PMID:28300665 PMID:28694203 PMID:32032644 PMID:34425168 PMID:35472619 More... NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdh2 cadherin 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CDH2 protein
OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein] 		CTD PMID:35654123 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cdk8 cyclin-dependent kinase 8 multiple interactions
increases expression 		ISO MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of CDK8 protein] CTD PMID:38460002 NCBI chr12:13,851,024...13,919,017
Ensembl chr12:13,851,024...13,917,992 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256 PMID:29720568 PMID:32554301 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
decreases response to substance
multiple interactions
increases response to substance 		ISO Bleomycin results in increased expression of CEBPB mRNA
CEBPB gene mutant form results in decreased susceptibility to Bleomycin
CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]
CEBPB protein results in increased susceptibility to Bleomycin 		CTD PMID:17177178 PMID:21998664 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression ISO Bleomycin results in decreased expression of CEMIP2 mRNA CTD PMID:33770205 NCBI chr 1:228,756,826...228,834,313
Ensembl chr 1:228,757,466...228,832,906 		JBrowse link
G Cenpe centromere protein E multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA] CTD PMID:30825431 NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636 		JBrowse link
G Cert1 ceramide transporter 1 increases expression ISO Bleomycin results in increased expression of CERT1 mRNA CTD PMID:36087614 NCBI chr 2:29,617,202...29,721,734
Ensembl chr 2:29,617,023...29,721,729 		JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Cfl1 cofilin 1 increases expression EXP Bleomycin results in increased expression of CFL1 protein CTD PMID:25933445 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions 		ISO Bleomycin results in increased phosphorylation of CHEK2 protein
resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein] 		CTD PMID:24933654 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression EXP Bleomycin results in decreased expression of CHRNB2 mRNA CTD PMID:15808516 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326 		JBrowse link
G Ckb creatine kinase B increases expression EXP Bleomycin results in increased expression of CKB protein CTD PMID:25933445 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478 		JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression EXP Bleomycin results in increased expression of CLCN5 mRNA CTD PMID:15808516 NCBI chr  X:17,857,260...18,011,844
Ensembl chr  X:17,857,260...18,011,844 		JBrowse link
G Cldn4 claudin 4 increases expression ISO Bleomycin results in increased expression of CLDN4 mRNA CTD PMID:26345256 NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958 		JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression EXP Bleomycin results in decreased expression of CLIC4 protein CTD PMID:25933445 NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118 		JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression EXP Bleomycin results in decreased expression of CLIC5 protein CTD PMID:25933445 NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780 		JBrowse link
G Cltc clathrin heavy chain decreases expression EXP Bleomycin results in decreased expression of CLTC protein CTD PMID:25933445 NCBI chr10:72,014,984...72,073,308
Ensembl chr10:72,014,986...72,070,691 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Bleomycin results in decreased expression of CNR1 mRNA CTD PMID:15808516 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Col11a2 collagen type XI alpha 2 chain increases expression ISO Bleomycin results in increased expression of COL11A2 mRNA CTD PMID:36087614 NCBI chr20:4,788,829...4,818,492
Ensembl chr20:4,788,829...4,817,648 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL14A1 mRNA CTD PMID:36087614 NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL18A1 mRNA CTD PMID:36087614 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression 		ISO
EXP 		5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; [Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein
Bleomycin results in decreased expression of COL1A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] 		CTD PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 More... NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of COL1A2 mRNA; Bleomycin results in increased expression of COL1A2 protein
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of COL1A2 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]
Bleomycin results in decreased expression of COL1A2 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein] 		CTD PMID:19147827 PMID:25933445 PMID:35472619 PMID:37163307 PMID:37307957 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col22a1 collagen type XXII alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL22A1 mRNA CTD PMID:36087614 NCBI chr 7:105,619,776...105,857,246
Ensembl chr 7:105,619,757...105,856,960 		JBrowse link
G Col24a1 collagen type XXIV alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL24A1 mRNA CTD PMID:36087614 NCBI chr 2:236,872,583...237,129,768
Ensembl chr 2:236,872,265...237,129,447 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression
increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of COL3A1 protein
Bleomycin results in increased expression of COL3A1 mRNA; Bleomycin results in increased expression of COL3A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]
honokiol inhibits the reaction [Bleomycin results in increased expression of COL3A1 protein] 		CTD PMID:25933445 PMID:26817844 PMID:28726637 PMID:32032644 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col4a4 collagen type IV alpha 4 chain increases expression ISO Bleomycin results in increased expression of COL4A4 mRNA CTD PMID:36087614 NCBI chr 9:91,281,324...91,323,577
Ensembl chr 9:91,203,670...91,323,577 		JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of COL5A1 protein
Bleomycin results in increased expression of COL5A1 mRNA 		CTD PMID:25933445 PMID:36087614 NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Bleomycin results in increased expression of COL5A2 mRNA CTD PMID:36087614 NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150 		JBrowse link
G Col5a3 collagen type V alpha 3 chain increases expression ISO Bleomycin results in increased expression of COL5A3 mRNA CTD PMID:36087614 NCBI chr 8:27,580,768...27,626,002
Ensembl chr 8:27,580,768...27,626,122 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Bleomycin results in increased expression of COL6A3 mRNA CTD PMID:36087614 NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990 		JBrowse link
G Col9a2 collagen type IX alpha 2 chain increases expression ISO Bleomycin results in increased expression of COL9A2 mRNA CTD PMID:36087614 NCBI chr 5:139,892,798...139,910,131
Ensembl chr 5:139,892,798...139,909,855 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression ISO Bleomycin results in increased expression of COLQ mRNA CTD PMID:36087614 NCBI chr16:6,738,251...6,830,492
Ensembl chr16:6,738,251...6,793,501 		JBrowse link
G Comp cartilage oligomeric matrix protein multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein CTD PMID:29033951 NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,081,172...19,089,605 		JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression 		ISO tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] CTD PMID:12624602 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Bleomycin affects the expression of CRIP2 protein CTD PMID:25933445 NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of CSF2 mRNA; Bleomycin results in increased expression of CSF2 protein
Bleomycin results in decreased expression of CSF2 mRNA
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA] 		CTD PMID:18684396 PMID:28299617 PMID:29720568 PMID:32554301 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Bleomycin results in increased expression of CSF2RB2 mRNA CTD PMID:36087614 NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654 		JBrowse link
G Csf3 colony stimulating factor 3 decreases expression EXP Bleomycin results in decreased expression of CSF3 mRNA CTD PMID:15808516 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Bleomycin results in increased expression of CSRP1 protein CTD PMID:25933445 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139 		JBrowse link
G Ctsa cathepsin A affects expression ISO Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 NCBI chr 3:173,988,443...173,994,320
Ensembl chr 3:173,988,460...173,995,539 		JBrowse link
G Ctsb cathepsin B affects expression ISO Bleomycin affects the expression of CTSB mRNA CTD PMID:26345256 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478 		JBrowse link
G Ctsh cathepsin H affects expression ISO Bleomycin affects the expression of CTSH mRNA CTD PMID:26345256 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181 		JBrowse link
G Ctss cathepsin S increases expression ISO Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CX3CL1 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of CX3CL1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CX3CL1 protein] 		CTD PMID:30825431 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression 		ISO 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA] CTD PMID:28299617 PMID:32554301 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of CXCL10 mRNA; Bleomycin results in increased expression of CXCL10 protein
Bleomycin results in decreased expression of CXCL10 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL10 protein 		CTD PMID:26345256 PMID:29720568 PMID:33516805 PMID:36087614 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Bleomycin results in increased expression of CXCL12 mRNA CTD PMID:29720568 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression ISO Bleomycin affects the expression of CXCL13 mRNA CTD PMID:26345256 NCBI chr14:13,912,858...13,917,920
Ensembl chr14:13,912,858...13,917,920 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO Bleomycin results in increased expression of CXCL14 mRNA CTD PMID:36087614 NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of CXCL2 protein
Bleomycin results in increased secretion of CXCL2 protein
Bleomycin results in increased expression of CXCL2 mRNA
3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL2 protein 		CTD PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 PMID:33516805 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases secretion
increases expression 		ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]
Bleomycin results in increased expression of CXCL1 protein
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA] 		CTD PMID:26600069 PMID:28299617 PMID:32554301 PMID:36087614 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CXCL9 protein CTD PMID:29175452 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Bleomycin results in increased expression of CXCR1 mRNA CTD PMID:36087614 NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression 		ISO Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of CYBA mRNA] CTD PMID:35187969 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Bleomycin affects the localization of CYCS protein CTD PMID:15371238 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Dbi diazepam binding inhibitor increases expression EXP Bleomycin results in increased expression of DBI protein CTD PMID:25933445 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions 		EXP Bleomycin results in increased expression of DDIT3 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of DDIT3 protein] 		CTD PMID:37163307 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Des desmin increases expression EXP Bleomycin results in increased expression of DES protein CTD PMID:25933445 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Bleomycin results in decreased expression of DLAT protein CTD PMID:29733421 NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:59,868,214...59,900,818
Ensembl chr 1:59,868,214...59,900,818 		JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression EXP
ISO 		Bleomycin results in increased expression of DLD protein CTD PMID:25933445 PMID:29733421 NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:53,619,631...53,652,354 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression ISO Bleomycin results in increased expression of DLK1 protein CTD PMID:29175452 NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of DLL4 protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of DLL4 protein] CTD PMID:30825431 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:126,770,794...126,780,763 		JBrowse link
G Dnm1l dynamin 1-like increases expression ISO Bleomycin results in increased expression of DNM1L protein CTD PMID:37126650 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420 		JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Bleomycin results in decreased expression of DPEP1 protein CTD PMID:25933445 NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression EXP Bleomycin results in decreased expression of ECH1 protein CTD PMID:25933445 NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression 		EXP Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Bleomycin results in increased expression of EEF1A1 protein CTD PMID:29733421 NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
affects expression 		ISO Bleomycin results in increased expression of EGR1 mRNA
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA]
Bleomycin affects the expression of EGR1 mRNA 		CTD PMID:19147827 PMID:26345256 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Egr2 early growth response 2 affects expression ISO Bleomycin affects the expression of EGR2 mRNA CTD PMID:26345256 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748 		JBrowse link
G Ehd1 EH-domain containing 1 decreases expression EXP Bleomycin results in decreased expression of EHD1 protein CTD PMID:25933445 NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485 		JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Bleomycin results in decreased expression of EHD2 protein CTD PMID:25933445 NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP Bleomycin results in increased expression of EIF5A protein CTD PMID:25933445 NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330 		JBrowse link
G Eln elastin increases expression ISO Bleomycin results in increased expression of ELN mRNA CTD PMID:26817844 NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413 		JBrowse link
G Emcn endomucin increases expression
multiple interactions 		ISO Bleomycin results in increased expression of EMCN mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA] 		CTD PMID:30825431 NCBI chr 2:228,564,445...228,644,370
Ensembl chr 2:228,564,430...228,645,155 		JBrowse link
G Eng endoglin multiple interactions
increases expression 		ISO Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ENG protein] CTD PMID:30825431 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Epx eosinophil peroxidase increases expression EXP Bleomycin results in increased expression of EPX protein CTD PMID:26093215 NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO Bleomycin results in decreased expression of ERRFI1 mRNA CTD PMID:33770205 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA] CTD PMID:30825431 NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS1 mRNA CTD PMID:28726637 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS2 mRNA CTD PMID:28726637 NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842 		JBrowse link
G Ezr ezrin decreases expression EXP Bleomycin results in decreased expression of EZR protein CTD PMID:25933445 NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression 		EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein]
Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein 		CTD PMID:23656969 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954 		JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Bleomycin results in decreased expression of FABP4 mRNA CTD PMID:29408570 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972 		JBrowse link
G Faslg Fas ligand increases expression ISO Bleomycin results in increased expression of FASLG mRNA CTD PMID:11350791 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FGF1 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF1 protein] 		CTD PMID:30825431 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of FGF2 protein
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF2 protein] 		CTD PMID:25582705 PMID:30825431 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf21 fibroblast growth factor 21 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of FGF21 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of FGF21 protein] 		CTD PMID:30825431 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FGF7 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF7 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of FGF7 protein] 		CTD PMID:30825431 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Bleomycin results in increased expression of FHL1 protein CTD PMID:25933445 NCBI chr  X:139,592,794...139,652,290
Ensembl chr  X:139,592,604...139,652,282 		JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Bleomycin results in increased expression of FKBP10 mRNA CTD PMID:36087614 NCBI chr10:85,845,801...85,858,361
Ensembl chr10:85,844,703...85,858,355 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of FN1 protein
[Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]; TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]
Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of FN1 protein] 		CTD PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 More... NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity
multiple interactions 		ISO Bleomycin results in increased activity of FOS protein
Bleomycin results in increased expression of [JUN protein binds to FOS protein] 		CTD PMID:12003776 PMID:37399107 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Bleomycin results in increased expression of FOXP3 mRNA CTD PMID:29033951 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Foxq1 forkhead box Q1 increases expression ISO Bleomycin results in increased expression of FOXQ1 mRNA CTD PMID:36087614 NCBI chr17:33,121,454...33,124,087
Ensembl chr17:33,121,545...33,123,720 		JBrowse link
G Foxr1 forkhead box R1 increases expression ISO Bleomycin results in increased expression of FOXR1 mRNA CTD PMID:36087614 NCBI chr 8:53,657,388...53,669,424
Ensembl chr 8:53,657,256...53,669,629 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FSHB protein
thymoquinone inhibits the reaction [Bleomycin results in increased expression of FSHB protein] 		CTD PMID:34818114 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of FSHR mRNA CTD PMID:15808516 NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288 		JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression EXP Bleomycin results in increased expression of FUBP1 protein CTD PMID:25933445 NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428 		JBrowse link
G Fzd6 frizzled class receptor 6 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FZD6 mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA] 		CTD PMID:28726637 NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression EXP Bleomycin results in decreased expression of GABRA4 mRNA CTD PMID:15808516 NCBI chr14:36,944,747...37,021,652
Ensembl chr14:36,944,388...37,021,648 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP Bleomycin results in decreased expression of GABRB2 mRNA CTD PMID:15808516 NCBI chr10:27,438,127...27,657,680
Ensembl chr10:27,438,238...27,655,171 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP Bleomycin results in decreased expression of GABRG2 mRNA CTD PMID:15808516 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,876,926...26,965,523 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression EXP Bleomycin results in decreased expression of GABRR1 mRNA CTD PMID:15808516 NCBI chr 5:52,320,475...52,357,549
Ensembl chr 5:52,320,475...52,357,549 		JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein CTD PMID:29733421 NCBI chr 1:215,222,918...215,242,808
Ensembl chr 1:215,222,995...215,243,036 		JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Bleomycin results in increased expression of GAS6 protein CTD PMID:29175452 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088 		JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of GATA3 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA] 		CTD PMID:29033951 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Bleomycin results in increased expression of GC protein CTD PMID:25933445 NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression 		ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gda guanine deaminase decreases expression EXP Bleomycin results in decreased expression of GDA protein CTD PMID:25933445 NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348 		JBrowse link
G Glb1 galactosidase, beta 1 increases activity ISO Bleomycin results in increased activity of GLB1 protein CTD PMID:32554301 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326 		JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression EXP Bleomycin results in decreased expression of GPI protein CTD PMID:25933445 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Bleomycin affects the expression of GPX1 protein CTD PMID:25933445 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Bleomycin results in decreased expression of GRIA2 mRNA CTD PMID:15808516 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Bleomycin results in decreased expression of GRIK3 mRNA CTD PMID:15808516 NCBI chr 5:143,052,442...143,268,873
Ensembl chr 5:143,052,442...143,268,873 		JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression EXP Bleomycin results in decreased expression of GRPR mRNA CTD PMID:15808516 NCBI chr  X:34,630,238...34,670,245
Ensembl chr  X:34,630,229...34,670,245 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation 		ISO [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsn gelsolin decreases expression EXP Bleomycin results in decreased expression of GSN protein CTD PMID:25933445 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions 		EXP Bleomycin results in decreased activity of GSR protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of GSR protein] 		CTD PMID:26768587 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP Bleomycin results in decreased expression of GSTM1 protein CTD PMID:25933445 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G H1f0 H1.0 linker histone affects expression EXP Bleomycin affects the expression of H1F0 protein CTD PMID:25933445 NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006 		JBrowse link
G H1f4 H1.4 linker histone, cluster member affects expression EXP Bleomycin affects the expression of H1F4 protein CTD PMID:25933445 NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,914,431...41,916,129 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Bleomycin results in decreased expression of HADHA protein CTD PMID:25933445 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Bleomycin results in increased expression of HAVCR1 protein CTD PMID:29175452 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268 		JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Bleomycin affects the expression of HBB protein CTD PMID:25933445 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain affects expression EXP Bleomycin affects the expression of HBB-B2 protein CTD PMID:25933445 NCBI chr 1:167,655,583...167,656,963 JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Bleomycin results in increased expression of HBEGF mRNA CTD PMID:18684396 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA] CTD PMID:30825431 NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387 		JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
increases secretion
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein
Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein]
Bleomycin results in increased secretion of HGF protein
Bleomycin results in increased expression of HGF mRNA
Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of HGF protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of HGF protein] 		CTD PMID:16115399 PMID:22687607 PMID:29408570 PMID:30825431 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression 		ISO [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hist1h2bg histone cluster 1, H2bg decreases expression EXP Bleomycin results in decreased expression of HIST1H2BG protein CTD PMID:25933445 NCBI chr17:41,999,269...42,000,237
Ensembl chr17:41,998,640...42,000,585 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific decreases expression ISO Bleomycin results in decreased expression of HMCES mRNA CTD PMID:33770205 NCBI chr 4:121,950,129...121,972,937
Ensembl chr 4:121,950,840...121,972,891 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression 		EXP
ISO 		protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA] 		CTD PMID:25582705 PMID:32278510 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of HMOX1 protein
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]
Bleomycin results in increased expression of HMOX1 mRNA
Bleomycin results in decreased expression of HMOX1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA] 		CTD PMID:16317386 PMID:26093215 PMID:26768587 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Bleomycin results in increased expression of HNRNPA2B1 protein CTD PMID:25933445 NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572 		JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 increases expression EXP Bleomycin results in increased expression of HNRNPA3 protein CTD PMID:25933445 NCBI chr 3:80,984,470...80,999,413
Ensembl chr 3:80,985,969...80,996,043 		JBrowse link
G Hpx hemopexin increases expression EXP Bleomycin results in increased expression of HPX protein CTD PMID:25933445 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions 		ISO Bleomycin results in increased expression of HSPA1A mRNA
geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1A mRNA] 		CTD PMID:37307957 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions 		ISO Bleomycin results in increased expression of HSPA1B mRNA
geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1B mRNA] 		CTD PMID:37307957 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions 		EXP Bleomycin results in increased expression of HSPA5 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of HSPA5 protein] 		CTD PMID:25933445 PMID:37163307 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP Bleomycin results in decreased expression of HSPB1 protein CTD PMID:25933445 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO 		Bleomycin results in increased expression of HSPE1 protein CTD PMID:25933445 PMID:29733421 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502 		JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F decreases expression EXP Bleomycin results in decreased expression of HTR1F mRNA CTD PMID:15808516 NCBI chr11:16,089,266...16,090,665
Ensembl chr11:16,081,053...16,274,580 		JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A decreases expression EXP Bleomycin results in decreased expression of HTR5A mRNA CTD PMID:15808516 NCBI chr 4:8,178,802...8,188,485
Ensembl chr 4:8,178,802...8,200,482 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B decreases expression EXP Bleomycin results in decreased expression of HTR5B mRNA CTD PMID:15808516 NCBI chr13:35,239,662...35,252,586
Ensembl chr13:35,239,662...35,252,586 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Bleomycin results in increased expression of ICAM1 mRNA CTD PMID:29033951 PMID:29720568 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP Bleomycin results in decreased expression of IDH2 protein CTD PMID:25933445 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of IFITM1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA] 		CTD PMID:30825431 NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776 		JBrowse link
G Ifng interferon gamma increases expression
decreases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of IFNG mRNA
Bleomycin results in decreased expression of IFNG mRNA
[SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG protein
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IFNG protein 		CTD PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 PMID:33516805 More... NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Bleomycin results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Ikbip IKBKB interacting protein increases expression ISO Bleomycin results in increased expression of IKBIP mRNA CTD PMID:36087614 NCBI chr 7:27,467,097...27,485,776
Ensembl chr 7:27,467,055...27,491,460 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
increases secretion 		ISO Bleomycin results in increased expression of IL10 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL10 protein]
bufotalin inhibits the reaction [Bleomycin results in increased expression of IL10 protein] 		CTD PMID:29175452 PMID:37898439 PMID:38158113 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Bleomycin results in increased expression of IL10RA mRNA CTD PMID:36087614 NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028 		JBrowse link
G Il12b interleukin 12B increases expression ISO Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 increases expression ISO Bleomycin results in increased expression of IL12RB2 mRNA CTD PMID:11350791 NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937 		JBrowse link
G Il13 interleukin 13 decreases response to substance
multiple interactions
increases expression 		ISO IL13 gene mutant form results in decreased susceptibility to Bleomycin
bufotalin inhibits the reaction [Bleomycin results in increased expression of IL13 protein]; IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA] 		CTD PMID:15322207 PMID:38158113 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA] CTD PMID:30825431 PMID:36087614 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA] CTD PMID:35716765 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il17rd interleukin 17 receptor D increases expression ISO Bleomycin results in increased expression of IL17RD mRNA CTD PMID:36087614 NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850 		JBrowse link
G Il17re interleukin 17 receptor E increases expression ISO Bleomycin results in increased expression of IL17RE mRNA CTD PMID:36087614 NCBI chr 4:148,160,384...148,173,830
Ensembl chr 4:148,159,475...148,173,827 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression 		ISO 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]; IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]
Bleomycin results in increased expression of IL1A protein 		CTD PMID:8317554 PMID:28299617 PMID:29175452 PMID:32554301 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion
affects expression 		ISO
EXP 		12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of IL1B mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of IL1B mRNA; bufotalin inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]
Bleomycin affects the expression of IL1B mRNA 		CTD PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Bleomycin results in increased expression of IL1RL1 mRNA; Bleomycin results in increased expression of IL1RL1 protein CTD PMID:37399107 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IL2 protein CTD PMID:33516805 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il33 interleukin 33 increases expression ISO Bleomycin results in increased expression of IL33 mRNA; Bleomycin results in increased expression of IL33 protein CTD PMID:36087614 PMID:37399107 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Il4 interleukin 4 increases expression
decreases response to substance
multiple interactions
affects response to substance
increases secretion 		ISO Bleomycin results in increased expression of IL4 mRNA
IL4 gene mutant form results in decreased susceptibility to Bleomycin
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]; IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]
IL4 protein affects the susceptibility to Bleomycin
Bleomycin results in increased secretion of IL4 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL4 protein] 		CTD PMID:11554783 PMID:12574379 PMID:15322207 PMID:30033591 PMID:37898439 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
increases secretion 		ISO
EXP 		Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; astragalin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; aurantio-obtusin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; caffeic acid inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; eleutheroside E inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; Ephedrine inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; linarin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; rhoifolin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; scoparone inhibits the reaction [Bleomycin results in increased secretion of IL6 protein] 		CTD PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il7 interleukin 7 increases expression ISO Bleomycin results in increased expression of IL7 protein CTD PMID:36087614 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] CTD PMID:30825431 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of ITGB2 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA] 		CTD PMID:30825431 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression EXP Bleomycin results in increased expression of JPT1 protein CTD PMID:25933445 NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases phosphorylation
multiple interactions 		ISO Bleomycin results in increased activity of JUN protein
Bleomycin results in increased phosphorylation of JUN protein
Bleomycin results in increased expression of [JUN protein binds to FOS protein]; Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein] 		CTD PMID:12003776 PMID:35716765 PMID:37399107 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of KEAP1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein]
Ephedrine inhibits the reaction [Bleomycin results in increased expression of KEAP1 protein] 		CTD PMID:26768587 PMID:37778983 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Bleomycin results in increased expression of KHSRP protein CTD PMID:25933445 NCBI chr 9:1,949,557...1,959,400
Ensembl chr 9:1,949,557...1,959,497 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions 		ISO Bleomycin results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein 		CTD PMID:29733421 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Kl Klotho decreases expression ISO Bleomycin results in decreased expression of KL mRNA CTD PMID:29408570 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015 		JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Bleomycin results in increased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 4:181,730,343...181,760,899
Ensembl chr 4:181,735,244...181,757,013 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene CTD PMID:12616606 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Krt13 keratin 13 increases expression ISO Bleomycin results in increased expression of KRT13 mRNA CTD PMID:36087614 NCBI chr10:85,552,287...85,556,499
Ensembl chr10:85,552,287...85,556,499 		JBrowse link
G Krt19 keratin 19 decreases expression EXP Bleomycin results in decreased expression of KRT19 protein CTD PMID:25933445 NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952 		JBrowse link
G Krt8 keratin 8 multiple interactions
decreases expression 		ISO Ephedrine inhibits the reaction [Bleomycin results in decreased expression of KRT8 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in decreased expression of KRT8 protein]
Bleomycin results in decreased expression of KRT8 mRNA; Bleomycin results in decreased expression of KRT8 protein 		CTD PMID:37778983 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403 		JBrowse link
G Krt87 keratin 87 increases expression ISO Bleomycin results in increased expression of KRT87 mRNA CTD PMID:36087614 NCBI chr 7:134,426,567...134,433,740
Ensembl chr 7:134,426,567...134,433,740 		JBrowse link
G Lap3 leucine aminopeptidase 3 increases expression EXP Bleomycin results in increased expression of LAP3 protein CTD PMID:25933445 NCBI chr14:69,820,907...69,839,891
Ensembl chr14:69,820,908...69,839,891 		JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression EXP Bleomycin results in increased expression of LASP1 protein CTD PMID:25933445 NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein CTD PMID:26345256 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of LCP1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA] 		CTD PMID:30825431 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092 		JBrowse link
G Ldhal1 lactate dehydrogenase A like 1 decreases expression EXP Bleomycin results in decreased expression of LDHAL1 protein CTD PMID:25933445 NCBI chr 8:38,621,351...38,622,975 JBrowse link
G Lep leptin increases expression ISO Bleomycin results in increased expression of LEP protein CTD PMID:29175452 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lgals3 galectin 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of LGALS3 protein
NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein] 		CTD PMID:26526764 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Lgals9 galectin 9 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of LGALS9 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA] 		CTD PMID:30825431 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression 		ISO thymoquinone inhibits the reaction [Bleomycin results in increased expression of LHB protein] CTD PMID:34818114 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA] CTD PMID:30825431 NCBI chr 2:139,276,810...139,474,740
Ensembl chr 2:139,276,789...139,474,737 		JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA CTD PMID:29733421 NCBI chr10:69,894,288...69,901,076
Ensembl chr10:69,894,288...69,901,076 		JBrowse link
G Liph lipase H decreases expression ISO Bleomycin results in decreased expression of LIPH mRNA CTD PMID:33770205 NCBI chr11:92,536,724...92,586,117
Ensembl chr11:92,537,860...92,586,120 		JBrowse link
G Lmna lamin A/C increases expression EXP Bleomycin results in increased expression of LMNA protein CTD PMID:25933445 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Lpxn leupaxin multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA] CTD PMID:30825431 NCBI chr 1:219,353,319...219,387,743
Ensembl chr 1:219,353,708...219,387,742 		JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP Bleomycin results in decreased expression of LYZ protein CTD PMID:25933445 NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011 		JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Bleomycin results in decreased expression of MACROH2A1 protein CTD PMID:25933445 NCBI chr17:8,484,340...8,547,268
Ensembl chr17:8,484,246...8,547,257 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions 		ISO Bleomycin results in increased expression of MAP1LC3B protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form] 		CTD PMID:31302203 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23570914 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23570914 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation 		ISO Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein] CTD PMID:35716765 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression EXP Bleomycin results in decreased expression of MARCKS protein CTD PMID:25933445 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882 		JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of MDH2 protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein 		CTD PMID:25933445 PMID:29733421 NCBI chr12:26,530,886...26,543,841
Ensembl chr12:26,530,881...26,543,841 		JBrowse link
G Mecp2 methyl CpG binding protein 2 affects response to substance ISO MECP2 protein affects the susceptibility to Bleomycin CTD PMID:21435439 NCBI chr  X:156,932,481...156,995,981
Ensembl chr  X:156,941,234...156,943,560 		JBrowse link
G Mepce methylphosphate capping enzyme increases expression ISO Bleomycin results in increased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr12:24,548,596...24,553,315
Ensembl chr12:24,548,596...24,553,877 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions
increases phosphorylation 		ISO Bleomycin affects the localization of and affects the expression of MERTK protein
Bleomycin results in increased phosphorylation of MERTK protein 		CTD PMID:22687607 NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192 		JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO Bleomycin results in decreased expression of MFN1 protein CTD PMID:37126650 NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190 		JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO Bleomycin results in decreased expression of MFN2 protein CTD PMID:37126650 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
G Mif macrophage migration inhibitory factor decreases expression EXP Bleomycin results in decreased expression of MIF protein CTD PMID:25933445 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mir100 microRNA 100 decreases expression EXP Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 NCBI chr 8:50,798,295...50,798,374
Ensembl chr 8:50,798,295...50,798,374 		JBrowse link
G Mir101-2 microRNA 101-2 decreases expression EXP
ISO 		Bleomycin results in decreased expression of MIR101B mRNA CTD PMID:25933445 PMID:28726637 NCBI chr 1:236,273,922...236,274,018
Ensembl chr 1:236,273,922...236,274,018 		JBrowse link
G Mir101a microRNA 101a multiple interactions
decreases expression 		ISO
EXP 		MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
Bleomycin results in decreased expression of MIR101A mRNA 		CTD PMID:25933445 PMID:28726637 NCBI chr 5:121,081,683...121,081,757 JBrowse link
G Mir106b microRNA 106b affects expression EXP Bleomycin affects the expression of MIR106B mRNA CTD PMID:25933445 NCBI chr12:22,157,053...22,157,134 JBrowse link
G Mir107 microRNA 107 decreases expression EXP Bleomycin results in decreased expression of MIR107 mRNA CTD PMID:25933445 NCBI chr 1:241,750,418...241,750,504 JBrowse link
G Mir10a microRNA 10a decreases expression EXP Bleomycin results in decreased expression of MIR10A mRNA CTD PMID:25933445 NCBI chr10:81,779,709...81,779,818
Ensembl chr10:81,779,709...81,779,818 		JBrowse link
G Mir10b microRNA 10b decreases expression EXP Bleomycin results in decreased expression of MIR10B mRNA CTD PMID:25933445 NCBI chr 3:80,035,859...80,035,967
Ensembl chr 3:80,035,859...80,035,967 		JBrowse link
G Mir1224 microRNA 1224 increases expression EXP Bleomycin results in increased expression of MIR1224 mRNA CTD PMID:25933445 NCBI chr11:93,811,291...93,811,375 JBrowse link
G Mir1249 microRNA 1249 affects expression EXP Bleomycin affects the expression of MIR1249 mRNA CTD PMID:25933445 NCBI chr 7:117,955,517...117,955,636 JBrowse link
G Mir125a microRNA 125a affects expression EXP Bleomycin affects the expression of MIR125A mRNA CTD PMID:25933445 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759 		JBrowse link
G Mir126a microRNA 126a decreases expression EXP Bleomycin results in decreased expression of MIR126 mRNA CTD PMID:25933445 NCBI chr 3:29,813,150...29,813,267 JBrowse link
G Mir130a microRNA 130a decreases expression EXP Bleomycin results in decreased expression of MIR130A mRNA CTD PMID:25933445 NCBI chr 3:90,229,228...90,229,315 JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression EXP Bleomycin results in decreased expression of MIR133A1 mRNA CTD PMID:25933445 NCBI chr18:2,157,872...2,157,958 JBrowse link
G Mir133b microRNA 133b decreases expression EXP Bleomycin results in decreased expression of MIR133B mRNA CTD PMID:25933445 NCBI chr 9:30,594,582...30,594,665
Ensembl chr 9:30,594,582...30,594,665 		JBrowse link
G Mir140 microRNA 140 affects expression EXP Bleomycin affects the expression of MIR140 mRNA CTD PMID:25933445 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:52,375,293...52,375,391 		JBrowse link
G Mir141 microRNA 141 affects expression EXP Bleomycin affects the expression of MIR141 mRNA CTD PMID:25933445 NCBI chr 4:159,209,525...159,209,618 JBrowse link
G Mir142 microRNA 142 decreases expression
increases expression 		EXP Bleomycin results in decreased expression of MIR142 mRNA
Bleomycin results in increased expression of MIR142 mRNA 		CTD PMID:25933445 NCBI chr10:73,055,104...73,055,190
Ensembl chr10:73,055,097...73,055,207 		JBrowse link
G Mir143 microRNA 143 decreases expression EXP Bleomycin results in decreased expression of MIR143 mRNA CTD PMID:25933445 NCBI chr18:57,371,349...57,371,453 JBrowse link
G Mir144 microRNA 144 decreases expression EXP Bleomycin results in decreased expression of MIR144 mRNA CTD PMID:25933445 NCBI chr10:63,459,397...63,459,479
Ensembl chr10:63,459,397...63,459,479 		JBrowse link
G Mir145 microRNA 145 decreases expression EXP Bleomycin results in decreased expression of MIR145 mRNA CTD PMID:25933445 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir146a microRNA 146a affects expression EXP Bleomycin affects the expression of MIR146A mRNA CTD PMID:25933445 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir146b microRNA 146b increases expression EXP Bleomycin results in increased expression of MIR146B mRNA CTD PMID:25933445 NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:255,144,860...255,144,947 		JBrowse link
G Mir148b microRNA 148b decreases expression EXP Bleomycin results in decreased expression of MIR148B mRNA CTD PMID:25933445 NCBI chr 7:136,299,870...136,299,966
Ensembl chr 7:136,299,870...136,299,966 		JBrowse link
G Mir150 microRNA 150 affects expression EXP Bleomycin affects the expression of MIR150 mRNA CTD PMID:25933445 NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:104,741,487...104,741,571 		JBrowse link
G Mir151 microRNA 151 decreases expression EXP Bleomycin results in decreased expression of MIR151 mRNA CTD PMID:25933445 NCBI chr 7:107,061,380...107,061,476 JBrowse link
G Mir152 microRNA 152 decreases expression EXP Bleomycin results in decreased expression of MIR152 mRNA CTD PMID:25933445 NCBI chr10:82,329,383...82,329,467
Ensembl chr10:82,329,383...82,329,467 		JBrowse link
G Mir15b microRNA 15b affects expression EXP Bleomycin affects the expression of MIR15B mRNA CTD PMID:25933445 NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:155,555,178...155,555,275 		JBrowse link
G Mir16-2 microRNA 16-2 decreases expression EXP Bleomycin results in decreased expression of MIR16-2 mRNA CTD PMID:25933445 NCBI chr 2:155,555,327...155,555,421
Ensembl chr 2:155,555,327...155,555,421 		JBrowse link
G Mir17 microRNA 17 affects expression EXP Bleomycin affects the expression of MIR17 mRNA CTD PMID:25933445 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:98,587,848...98,587,931 		JBrowse link
G Mir181a-1 microRNA 181a-1 decreases expression EXP Bleomycin results in decreased expression of MIR181A-1 mRNA CTD PMID:25933445 NCBI chr13:52,037,067...52,037,166 JBrowse link
G Mir181c microRNA 181c decreases expression EXP Bleomycin results in decreased expression of MIR181C mRNA CTD PMID:25933445 NCBI chr19:40,888,291...40,888,396
Ensembl chr19:40,888,291...40,888,396 		JBrowse link
G Mir181d microRNA 181d decreases expression EXP Bleomycin results in decreased expression of MIR181D mRNA CTD PMID:25933445 NCBI chr19:40,888,474...40,888,556
Ensembl chr19:40,888,474...40,888,556 		JBrowse link
G Mir182 microRNA 182 increases expression
affects expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of MIR182 mRNA
Bleomycin affects the expression of MIR182 mRNA
MIR182 affects the reaction [Bleomycin results in decreased expression of SMAD7 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of FN1 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of TGFB1 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein] 		CTD PMID:25933445 PMID:31884830 NCBI chr 4:59,752,246...59,752,307 JBrowse link
G Mir183 microRNA 183 affects expression EXP Bleomycin affects the expression of MIR183 mRNA CTD PMID:25933445 NCBI chr 4:59,756,044...59,756,153 JBrowse link
G Mir185 microRNA 185 decreases expression EXP Bleomycin results in decreased expression of MIR185 mRNA CTD PMID:25933445 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:96,169,028...96,169,107 		JBrowse link
G Mir186 microRNA 186 decreases expression EXP Bleomycin results in decreased expression of MIR186 mRNA CTD PMID:25933445 NCBI chr 2:249,241,650...249,241,735
Ensembl chr 2:249,241,650...249,241,735 		JBrowse link
G Mir188 microRNA 188 affects expression EXP Bleomycin affects the expression of MIR188 mRNA CTD PMID:25933445 NCBI chr  X:17,919,585...17,919,664
Ensembl chr  X:17,919,585...17,919,664 		JBrowse link
G Mir18a microRNA 18a increases expression EXP Bleomycin results in increased expression of MIR18A mRNA CTD PMID:25933445 NCBI chr15:98,587,984...98,588,079
Ensembl chr15:98,587,984...98,588,079 		JBrowse link
G Mir193 microRNA 193 decreases expression EXP Bleomycin results in decreased expression of MIR193 mRNA CTD PMID:25933445 NCBI chr10:65,170,317...65,170,402 JBrowse link
G Mir1949 microRNA 1949 increases expression EXP Bleomycin results in increased expression of MIR1949 mRNA CTD PMID:25933445 NCBI chr18:27,429,688...27,429,784
Ensembl chr18:27,429,688...27,429,784 		JBrowse link
G Mir195 microRNA 195 decreases expression EXP Bleomycin results in decreased expression of MIR195 mRNA CTD PMID:25933445 NCBI chr10:55,450,495...55,450,581
Ensembl chr10:55,450,495...55,450,581 		JBrowse link
G Mir199a2 microRNA 199a-2 affects expression EXP Bleomycin affects the expression of MIR199A2 mRNA CTD PMID:25933445 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:77,116,225...77,116,334 		JBrowse link
G Mir19a microRNA 19a affects expression EXP Bleomycin affects the expression of MIR19A mRNA CTD PMID:25933445 NCBI chr15:98,588,131...98,588,212
Ensembl chr15:98,588,131...98,588,212 		JBrowse link
G Mir200a microRNA 200a decreases expression EXP Bleomycin results in decreased expression of MIR200A mRNA CTD PMID:25933445 NCBI chr 5:171,930,717...171,930,805 JBrowse link
G Mir200b microRNA 200b decreases expression EXP Bleomycin results in decreased expression of MIR200B mRNA CTD PMID:25933445 NCBI chr 5:171,931,495...171,931,589 JBrowse link
G Mir200c microRNA 200c decreases expression EXP Bleomycin results in decreased expression of MIR200C mRNA CTD PMID:25933445 NCBI chr 4:159,209,965...159,210,033 JBrowse link
G Mir203 microRNA 203 decreases expression EXP Bleomycin results in decreased expression of MIR203 mRNA CTD PMID:25933445 NCBI chr 6:137,020,691...137,020,805 JBrowse link
G Mir204 microRNA 204 decreases expression EXP Bleomycin results in decreased expression of MIR204 mRNA CTD PMID:25933445 NCBI chr 1:229,743,461...229,743,570
Ensembl chr 1:229,743,461...229,743,570 		JBrowse link
G Mir20a microRNA 20a affects expression EXP Bleomycin affects the expression of MIR20A mRNA CTD PMID:25933445 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:98,588,303...98,588,387 		JBrowse link
G Mir20b microRNA 20b affects expression EXP Bleomycin affects the expression of MIR20B mRNA CTD PMID:25933445 NCBI chr  X:137,343,197...137,343,268 JBrowse link
G Mir21 microRNA 21 increases expression EXP Bleomycin results in increased expression of MIR21 mRNA CTD PMID:25933445 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mir210 microRNA 210 decreases expression EXP Bleomycin results in decreased expression of MIR210 mRNA CTD PMID:25933445 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034 		JBrowse link
G Mir211 microRNA 211 affects expression EXP Bleomycin affects the expression of MIR211 mRNA CTD PMID:25933445 NCBI chr 1:127,189,328...127,189,433
Ensembl chr 1:127,189,328...127,189,433 		JBrowse link
G Mir212 microRNA 212 affects expression EXP Bleomycin affects the expression of MIR212 mRNA CTD PMID:25933445 NCBI chr10:60,521,740...60,521,850
Ensembl chr10:60,521,740...60,521,850 		JBrowse link
G Mir214 microRNA 214 affects expression EXP Bleomycin affects the expression of MIR214 mRNA CTD PMID:25933445 NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752 		JBrowse link
G Mir22 microRNA 22 affects expression EXP Bleomycin affects the expression of MIR22 mRNA CTD PMID:25933445 NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425 		JBrowse link
G Mir221 microRNA 221 decreases expression EXP Bleomycin results in decreased expression of MIR221 mRNA CTD PMID:25933445 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:6,023,182...6,023,290 		JBrowse link
G Mir222 microRNA 222 decreases expression
affects expression 		EXP Bleomycin results in decreased expression of MIR222 mRNA
Bleomycin affects the expression of MIR222 mRNA 		CTD PMID:25933445 PMID:34425168 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:6,022,621...6,022,723 		JBrowse link
G Mir223 microRNA 223 affects expression EXP Bleomycin affects the expression of MIR223 mRNA CTD PMID:25933445 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:65,151,383...65,151,492 		JBrowse link
G Mir23a microRNA 23a decreases expression EXP Bleomycin results in decreased expression of MIR23A mRNA CTD PMID:25933445 NCBI chr19:40,859,769...40,859,843 JBrowse link
G Mir23b microRNA 23b decreases expression EXP Bleomycin results in decreased expression of MIR23B mRNA CTD PMID:25933445 NCBI chr17:1,819,386...1,819,482 JBrowse link
G Mir24-2 microRNA 24-2 decreases expression EXP Bleomycin results in decreased expression of MIR24-2 mRNA CTD PMID:25933445 NCBI chr19:40,859,455...40,859,562 JBrowse link
G Mir25 microRNA 25 affects expression EXP Bleomycin affects the expression of MIR25 mRNA CTD PMID:25933445 NCBI chr12:22,156,641...22,156,724 JBrowse link
G Mir26a1 microRNA 26a-1 decreases expression ISO Bleomycin results in decreased expression of MIR26A-1 CTD PMID:35785413 NCBI chr 8:127,633,048...127,633,137
Ensembl chr 8:127,633,048...127,633,137 		JBrowse link
G Mir26b microRNA 26b decreases expression EXP Bleomycin results in decreased expression of MIR26B mRNA CTD PMID:25933445 NCBI chr 9:83,425,709...83,425,793
Ensembl chr 9:83,425,709...83,425,793 		JBrowse link
G Mir27a microRNA 27a decreases expression EXP Bleomycin results in decreased expression of MIR27A mRNA CTD PMID:25933445 NCBI chr19:40,859,603...40,859,689 JBrowse link
G Mir27b microRNA 27b decreases expression EXP Bleomycin results in decreased expression of MIR27B mRNA CTD PMID:25933445 NCBI chr17:1,819,147...1,819,243 JBrowse link
G Mir28 microRNA 28 decreases expression EXP Bleomycin results in decreased expression of MIR28 mRNA CTD PMID:25933445 NCBI chr11:89,480,252...89,480,337 JBrowse link
G Mir290 microRNA 290 increases expression EXP Bleomycin results in increased expression of MIR290 mRNA CTD PMID:25933445 NCBI chr 1:74,880,055...74,880,135 JBrowse link
G Mir296 microRNA 296 affects expression EXP Bleomycin affects the expression of MIR296 mRNA CTD PMID:25933445 NCBI chr 3:183,470,069...183,470,146 JBrowse link
G Mir2985 microRNA 2985 affects expression EXP Bleomycin affects the expression of MIR2985 mRNA CTD PMID:25933445 NCBI chr 2:168,254,500...168,254,609 JBrowse link
G Mir29a microRNA 29a decreases expression EXP Bleomycin results in decreased expression of MIR29A mRNA CTD PMID:25933445 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir29c microRNA 29c decreases expression EXP Bleomycin results in decreased expression of MIR29C mRNA CTD PMID:25933445 NCBI chr13:109,099,359...109,099,446 JBrowse link
G Mir301a microRNA 301a affects expression EXP Bleomycin affects the expression of MIR301A mRNA CTD PMID:25933445 NCBI chr10:72,422,599...72,422,698
Ensembl chr10:72,422,599...72,422,698 		JBrowse link
G Mir3085 microRNA 3085 decreases expression EXP Bleomycin results in decreased expression of MIR3085 mRNA CTD PMID:25933445 NCBI chr 1:251,038,184...251,038,272 JBrowse link
G Mir30a microRNA 30a decreases expression EXP Bleomycin results in decreased expression of MIR30A mRNA CTD PMID:25933445 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011 		JBrowse link
G Mir30b microRNA 30b decreases expression EXP Bleomycin results in decreased expression of MIR30B mRNA CTD PMID:25933445 NCBI chr 7:102,021,543...102,021,629 JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression EXP Bleomycin results in decreased expression of MIR30C2 mRNA CTD PMID:25933445 NCBI chr 9:33,253,682...33,253,765
Ensembl chr 9:33,253,682...33,253,765 		JBrowse link
G Mir30d microRNA 30d decreases expression EXP Bleomycin results in decreased expression of MIR30D mRNA CTD PMID:25933445 NCBI chr 7:102,025,345...102,025,426 JBrowse link
G Mir30e microRNA 30e decreases expression EXP Bleomycin results in decreased expression of MIR30E mRNA CTD PMID:25933445 NCBI chr 5:139,637,450...139,637,541
Ensembl chr 5:139,637,450...139,637,541 		JBrowse link
G Mir31 microRNA 31 decreases expression EXP Bleomycin results in decreased expression of MIR31 mRNA CTD PMID:25933445 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir32 microRNA 32 increases expression EXP Bleomycin results in increased expression of MIR32 mRNA CTD PMID:25933445 NCBI chr 5:76,391,285...76,391,354 JBrowse link
G Mir320a microRNA 320a decreases expression EXP Bleomycin results in decreased expression of MIR320A mRNA CTD PMID:25933445 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169 		JBrowse link
G Mir322 microRNA 322 decreases expression EXP Bleomycin results in decreased expression of MIR322 mRNA CTD PMID:25933445 NCBI chr  X:137,726,147...137,726,241 JBrowse link
G Mir324 microRNA 324 affects expression EXP Bleomycin affects the expression of MIR324 mRNA CTD PMID:25933445 NCBI chr10:55,233,363...55,233,445
Ensembl chr10:55,233,361...55,233,449 		JBrowse link
G Mir326 microRNA 326 decreases expression EXP Bleomycin results in decreased expression of MIR326 mRNA CTD PMID:25933445 NCBI chr 1:163,266,165...163,266,259
Ensembl chr 1:163,266,165...163,266,259 		JBrowse link
G Mir328 microRNA 328 affects expression EXP Bleomycin affects the expression of MIR328 mRNA CTD PMID:25933445 NCBI chr19:50,094,691...50,094,774 JBrowse link
G Mir33 microRNA 33 decreases expression EXP Bleomycin results in decreased expression of MIR33 mRNA CTD PMID:25933445 NCBI chr 7:115,593,952...115,594,020
Ensembl chr 7:115,593,952...115,594,020 		JBrowse link
G Mir330 microRNA 330 decreases expression EXP Bleomycin results in decreased expression of MIR330 mRNA CTD PMID:25933445 NCBI chr 1:87,961,207...87,961,303
Ensembl chr 1:87,961,207...87,961,303 		JBrowse link
G Mir331 microRNA 331 decreases expression EXP Bleomycin results in decreased expression of MIR331 mRNA CTD PMID:25933445 NCBI chr 7:30,414,386...30,414,481 JBrowse link
G Mir338 microRNA 338 decreases expression EXP Bleomycin results in decreased expression of MIR338 mRNA CTD PMID:25933445 NCBI chr10:105,796,342...105,796,407 JBrowse link
G Mir340 microRNA 340 increases expression EXP Bleomycin results in increased expression of MIR340 mRNA CTD PMID:25933445 NCBI chr10:34,894,650...34,894,747
Ensembl chr10:34,894,650...34,894,747 		JBrowse link
G Mir342 microRNA 342 decreases expression EXP Bleomycin results in decreased expression of MIR342 mRNA CTD PMID:25933445 NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:133,329,655...133,329,753 		JBrowse link
G Mir345 microRNA 345 decreases expression EXP Bleomycin results in decreased expression of MIR345 mRNA CTD PMID:25933445 NCBI chr 6:133,518,403...133,518,498
Ensembl chr 6:133,518,403...133,518,498 		JBrowse link
G Mir347 microRNA mir-347 decreases expression EXP Bleomycin results in decreased expression of MIR347 mRNA CTD PMID:25933445
G Mir3473 microRNA 3473 increases expression EXP Bleomycin results in increased expression of MIR3473 mRNA CTD PMID:25933445 NCBI chr13:42,051,691...42,051,757
Ensembl chr13:42,051,691...42,051,757 		JBrowse link
G Mir34a microRNA 34a affects expression
decreases expression 		EXP Bleomycin affects the expression of MIR34A mRNA
Bleomycin results in decreased expression of MIR34A mRNA 		CTD PMID:25933445 PMID:34425168 NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053 		JBrowse link
G Mir34b microRNA 34b decreases expression EXP Bleomycin results in decreased expression of MIR34B mRNA CTD PMID:25933445 NCBI chr 8:60,306,609...60,306,692 JBrowse link
G Mir34c microRNA 34c decreases expression EXP Bleomycin results in decreased expression of MIR34C mRNA CTD PMID:25933445 NCBI chr 8:60,306,091...60,306,167 JBrowse link
G Mir352 microRNA mir-352 decreases expression EXP Bleomycin results in decreased expression of MIR352 mRNA CTD PMID:25933445
G Mir3573 microRNA 3573 decreases expression EXP Bleomycin results in decreased expression of MIR3573 mRNA CTD PMID:25933445 NCBI chr  X:68,299,274...68,299,345
Ensembl chr  X:68,299,274...68,299,345 		JBrowse link
G Mir3584 microRNA 3584 affects expression EXP Bleomycin affects the expression of MIR3584 mRNA CTD PMID:25933445 NCBI chr 1:256,727,531...256,727,611 JBrowse link
G Mir361 microRNA 361 decreases expression EXP Bleomycin results in decreased expression of MIR361 mRNA CTD PMID:25933445 NCBI chr  X:82,438,463...82,438,532 JBrowse link
G Mir362 microRNA 362 affects expression EXP Bleomycin affects the expression of MIR362 mRNA CTD PMID:25933445 NCBI chr  X:17,926,485...17,926,549
Ensembl chr  X:17,926,485...17,926,549 		JBrowse link
G Mir365b microRNA 365b decreases expression EXP Bleomycin results in decreased expression of MIR365B mRNA CTD PMID:25933445 NCBI chr10:65,184,217...65,184,302
Ensembl chr10:65,184,214...65,184,313 		JBrowse link
G Mir374b microRNA 374b decreases expression EXP Bleomycin results in decreased expression of MIR374B mRNA CTD PMID:25933445 NCBI chr  X:72,657,495...72,657,562 JBrowse link
G Mir375 microRNA 375 decreases expression EXP Bleomycin results in decreased expression of MIR375 mRNA CTD PMID:25933445 NCBI chr 9:83,906,582...83,906,656 JBrowse link
G Mir378 microRNA 378 decreases expression EXP Bleomycin results in decreased expression of MIR378 mRNA CTD PMID:25933445 NCBI chr18:57,128,922...57,128,986 JBrowse link
G Mir409 microRNA 409 affects expression EXP Bleomycin affects the expression of MIR409 mRNA CTD PMID:25933445 NCBI chr 6:134,579,185...134,579,261 JBrowse link
G Mir423 microRNA 423 decreases expression EXP Bleomycin results in decreased expression of MIR423 mRNA CTD PMID:25933445 NCBI chr10:62,412,272...62,412,350 JBrowse link
G Mir425 microRNA 425 affects expression EXP Bleomycin affects the expression of MIR425 mRNA CTD PMID:25933445 NCBI chr 8:118,143,084...118,143,166
Ensembl chr 8:118,143,084...118,143,166 		JBrowse link
G Mir429 microRNA 429 decreases expression EXP Bleomycin results in decreased expression of MIR429 mRNA CTD PMID:25933445 NCBI chr 5:171,929,682...171,929,766 JBrowse link
G Mir449a microRNA 449a affects expression EXP Bleomycin affects the expression of MIR449A mRNA CTD PMID:25933445 NCBI chr 2:46,403,910...46,404,000
Ensembl chr 2:46,403,910...46,404,000 		JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP Bleomycin results in decreased expression of MIR450A1 mRNA CTD PMID:25933445 NCBI chr  X:137,720,933...137,721,023 JBrowse link
G Mir451a microRNA 451a decreases expression EXP
ISO 		Bleomycin results in decreased expression of MIR451A mRNA
Bleomycin results in decreased expression of MIR451A protein 		CTD PMID:25933445 PMID:34460027 NCBI chr10:63,459,569...63,459,640
Ensembl chr10:63,459,569...63,459,640 		JBrowse link
G Mir466b-1 microRNA mir-466b-1 decreases expression EXP Bleomycin results in decreased expression of MIR466B-1 mRNA CTD PMID:25933445 NCBI chr17:72,945,493...72,945,578 JBrowse link
G Mir483 microRNA 483 affects expression EXP Bleomycin affects the expression of MIR483 mRNA CTD PMID:25933445 NCBI chr 1:207,247,859...207,247,931 JBrowse link
G Mir494 microRNA 494 decreases expression EXP Bleomycin results in decreased expression of MIR494 mRNA CTD PMID:25933445 NCBI chr 6:134,550,115...134,550,197
Ensembl chr 6:134,550,114...134,550,198 		JBrowse link
G Mir497 microRNA 497 decreases expression EXP Bleomycin results in decreased expression of MIR497 mRNA CTD PMID:25933445 NCBI chr10:55,450,171...55,450,239
Ensembl chr10:55,450,162...55,450,241 		JBrowse link
G Mir500 microRNA 500 affects expression EXP Bleomycin affects the expression of MIR500 mRNA CTD PMID:25933445 NCBI chr  X:17,930,647...17,930,726
Ensembl chr  X:17,930,637...17,930,728 		JBrowse link
G Mir503 microRNA 503 decreases expression EXP Bleomycin results in decreased expression of MIR503 mRNA CTD PMID:25933445 NCBI chr  X:137,725,856...137,725,926 JBrowse link
G Mir511 microRNA 511 increases expression EXP Bleomycin results in increased expression of MIR511 mRNA CTD PMID:25933445 NCBI chr17:82,187,953...82,188,031
Ensembl chr17:82,187,953...82,188,031 		JBrowse link
G Mir532 microRNA 532 affects expression EXP Bleomycin affects the expression of MIR532 mRNA CTD PMID:25933445 NCBI chr  X:17,919,185...17,919,263
Ensembl chr  X:17,919,185...17,919,263 		JBrowse link
G Mir542 microRNA 542 decreases expression EXP Bleomycin results in decreased expression of MIR542 mRNA CTD PMID:25933445 NCBI chr  X:137,722,176...137,722,254 JBrowse link
G Mir6215 microRNA 6215 decreases expression EXP Bleomycin results in decreased expression of MIR6215 mRNA CTD PMID:25933445 NCBI chr 5:157,133,945...157,134,011 JBrowse link
G Mir6216 microRNA 6216 decreases expression EXP Bleomycin results in decreased expression of MIR6216 mRNA CTD PMID:25933445 NCBI chr 3:65,165,553...65,165,630 JBrowse link
G Mir6328 microRNA 6328 affects expression EXP Bleomycin affects the expression of MIR6328 mRNA CTD PMID:25933445 NCBI chr20:2,890,103...2,890,199
Ensembl chr20:2,890,103...2,890,199 		JBrowse link
G Mir652 microRNA 652 affects expression EXP Bleomycin affects the expression of MIR652 mRNA CTD PMID:25933445 NCBI chr  X:111,140,079...111,140,159
Ensembl chr  X:111,140,079...111,140,159 		JBrowse link
G Mir672 microRNA 672 decreases expression EXP Bleomycin results in decreased expression of MIR672 mRNA CTD PMID:25933445 NCBI chr  X:73,192,304...73,192,383 JBrowse link
G Mir674 microRNA 674 affects expression EXP Bleomycin affects the expression of MIR674 mRNA CTD PMID:25933445 NCBI chr 3:124,507,170...124,507,246
Ensembl chr 3:124,507,170...124,507,246 		JBrowse link
G Mir702 microRNA 702 affects expression EXP Bleomycin affects the expression of MIR702 mRNA CTD PMID:25933445 NCBI chr12:25,318,495...25,318,601 JBrowse link
G Mir872 microRNA 872 decreases expression EXP Bleomycin results in decreased expression of MIR872 mRNA CTD PMID:25933445 NCBI chr 5:114,654,823...114,654,903
Ensembl chr 5:114,654,823...114,654,903 		JBrowse link
G Mir93 microRNA 93 affects expression EXP Bleomycin affects the expression of MIR93 mRNA CTD PMID:25933445 NCBI chr12:22,156,844...22,156,930 JBrowse link
G Mir96 microRNA 96 affects expression EXP Bleomycin affects the expression of MIR96 mRNA CTD PMID:25933445 NCBI chr 4:59,755,841...59,755,946 JBrowse link
G Mir98 microRNA 98 decreases expression EXP Bleomycin results in decreased expression of MIR98 mRNA CTD PMID:25933445 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:24,460,648...24,460,755 		JBrowse link
G Mir99a microRNA 99a decreases expression EXP Bleomycin results in decreased expression of MIR99A mRNA CTD PMID:25933445 NCBI chr11:29,687,392...29,687,472
Ensembl chr11:29,687,392...29,687,472 		JBrowse link
G Mir99b microRNA 99b decreases expression EXP Bleomycin results in decreased expression of MIR99B mRNA CTD PMID:25933445 NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:67,350,060...67,350,139 		JBrowse link
G Mirlet7b microRNA let-7b decreases expression EXP Bleomycin results in decreased expression of MIRLET7B mRNA CTD PMID:25933445 NCBI chr 7:118,684,038...118,684,122
Ensembl chr 7:118,684,038...118,684,122 		JBrowse link
G Mirlet7d microRNA let-7d decreases expression EXP Bleomycin results in decreased expression of MIRLET7D mRNA CTD PMID:25933445 NCBI chr17:16,322,260...16,322,357
Ensembl chr17:16,322,260...16,322,357 		JBrowse link
G Mirlet7e microRNA let-7e decreases expression EXP Bleomycin results in decreased expression of MIRLET7E mRNA CTD PMID:25933445 NCBI chr 1:67,350,229...67,350,321 JBrowse link
G Mirlet7i microRNA let-7i decreases expression EXP Bleomycin results in decreased expression of MIRLET7I mRNA CTD PMID:25933445 NCBI chr 7:60,527,877...60,527,961 JBrowse link
G Mkln1 muskelin 1 multiple interactions
increases expression 		ISO MKLN1 mRNA alternative form affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of CDK8 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of VIM protein]
Bleomycin results in increased expression of MKLN1 mRNA alternative form 		CTD PMID:38460002 NCBI chr 4:60,939,239...61,095,214
Ensembl chr 4:60,937,817...61,095,210 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression 		EXP
ISO 		allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]
Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein
Bleomycin results in increased expression of and results in increased secretion of MMP2 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP2 mRNA] 		CTD PMID:23656969 PMID:26345256 PMID:26768587 PMID:29175452 PMID:35716765 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Bleomycin results in increased expression of MMP23 mRNA CTD PMID:36087614 NCBI chr 5:171,521,905...171,525,007
Ensembl chr 5:171,520,494...171,524,695 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression 		ISO [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA] 		CTD PMID:28299617 PMID:28434932 PMID:32554301 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of MMP7 protein
honokiol inhibits the reaction [Bleomycin results in increased expression of MMP7 protein] 		CTD PMID:32032644 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of MMP9 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]
Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Bleomycin results in increased expression of and results in increased secretion of MMP9 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein] 		CTD PMID:23656969 PMID:26526764 PMID:26768587 PMID:28300665 PMID:28694203 More... NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression 		ISO
EXP 		Oils, Volatile inhibits the reaction [Bleomycin results in increased activity of MPO protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein]
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein] 		CTD PMID:16317386 PMID:17035056 PMID:17118201 PMID:26093215 PMID:28850077 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Bleomycin results in increased expression of MRC1 mRNA CTD PMID:29033951 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Msn moesin decreases expression EXP Bleomycin results in decreased expression of MSN protein CTD PMID:25933445 NCBI chr  X:65,005,546...65,073,512
Ensembl chr  X:65,005,458...65,075,129 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of MUC5AC mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA] 		CTD PMID:18684396 PMID:26093215 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006 		JBrowse link
G Mucl3 mucin like 3 increases expression ISO Bleomycin results in increased expression of MUCL3 mRNA CTD PMID:36087614 NCBI chr20:3,105,360...3,113,278
Ensembl chr20:3,105,360...3,113,278 		JBrowse link
G Mug2 murinoglobulin 2 increases expression EXP Bleomycin results in increased expression of PZP protein CTD PMID:25933445 NCBI chr 4:156,836,140...156,908,972 JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Bleomycin results in decreased expression of MXI1 mRNA CTD PMID:33770205 NCBI chr 1:262,329,274...262,389,037
Ensembl chr 1:262,328,875...262,389,036 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance ISO MYC protein results in increased susceptibility to Bleomycin CTD PMID:10449034 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myh11 myosin heavy chain 11 decreases expression EXP Bleomycin results in decreased expression of MYH11 protein CTD PMID:25933445 NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Bleomycin results in decreased expression of MYH6 protein CTD PMID:25933445 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333 		JBrowse link
G Myl12b myosin light chain 12B increases expression EXP Bleomycin results in increased expression of MYL12B protein CTD PMID:25933445 NCBI chr 9:118,320,479...118,334,810
Ensembl chr 9:118,320,489...118,324,418 		JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP Bleomycin results in decreased expression of MYL4 protein CTD PMID:25933445 NCBI chr10:89,949,733...89,985,308
Ensembl chr10:89,949,404...89,985,308 		JBrowse link
G Myl6 myosin light chain 6 increases expression EXP Bleomycin results in increased expression of MYL6 protein CTD PMID:25933445 NCBI chr 7:1,495,301...1,498,512
Ensembl chr 7:1,495,747...1,498,344 		JBrowse link
G Myo1c myosin 1C decreases expression EXP Bleomycin results in decreased expression of MYO1C protein CTD PMID:25933445 NCBI chr10:60,996,642...61,019,022
Ensembl chr10:60,996,638...61,019,022 		JBrowse link
G Myo1e myosin IE decreases expression ISO Bleomycin results in decreased expression of MYO1E mRNA CTD PMID:33770205 NCBI chr 8:79,768,828...79,961,048
Ensembl chr 8:79,753,596...79,961,045 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Bleomycin results in decreased expression of NAP1L1 protein CTD PMID:29733421 NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions
increases expression 		ISO MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] CTD PMID:28726637 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
increases phosphorylation
decreases expression
multiple interactions
increases expression 		ISO
EXP 		Bleomycin affects the localization of NFE2L2 protein
Bleomycin results in increased phosphorylation of NFE2L2 protein
Bleomycin results in decreased expression of NFE2L2 protein
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin affects the localization of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of NFE2L2 protein]
Bleomycin results in increased expression of NFE2L2 protein
Bleomycin results in decreased expression of NFE2L2 mRNA; Bleomycin results in decreased expression of NFE2L2 protein
Berberine promotes the reaction [Bleomycin results in increased expression of NFE2L2 protein]; celastrol inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]
Ephedrine inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein] 		CTD PMID:23523906 PMID:23570914 PMID:26093215 PMID:26768587 PMID:37778983 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
increases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased activity of NFKB1 protein
Bleomycin results in increased expression of NFKB1 mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]
NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein] 		CTD PMID:12003776 PMID:26093215 PMID:26526764 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression
multiple interactions 		ISO Bleomycin results in increased expression of NFKBIZ mRNA; Bleomycin results in increased expression of NFKBIZ protein
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of NFKBIZ mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of NFKBIZ protein] 		CTD PMID:28299617 PMID:32554301 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression EXP Bleomycin results in increased expression of NHERF1 protein CTD PMID:25933445 NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579 		JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 decreases expression EXP Bleomycin results in decreased expression of NHERF2 protein CTD PMID:25933445 NCBI chr10:14,167,005...14,177,519
Ensembl chr10:14,167,005...14,177,593 		JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr11:56,832,957...56,844,142
Ensembl chr11:56,832,558...56,844,141 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 increases expression ISO Bleomycin results in increased expression of NLRP10 mRNA CTD PMID:36087614 NCBI chr 1:172,357,648...172,365,205
Ensembl chr 1:172,357,648...172,365,205 		JBrowse link
G Nmbr neuromedin B receptor decreases expression EXP Bleomycin results in decreased expression of NMBR mRNA CTD PMID:15808516 NCBI chr 1:10,942,476...10,966,174
Ensembl chr 1:10,954,916...10,965,555 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Bleomycin results in increased expression of NME2 protein CTD PMID:25933445 NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
increases secretion 		ISO
EXP 		Bleomycin results in increased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; rosiglitazone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased expression of NOS2 mRNA; Bleomycin results in increased expression of NOS2 protein
Berberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased secretion of NOS2 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of NOS2 protein] 		CTD PMID:15684285 PMID:17434272 PMID:19362168 PMID:23523906 PMID:26526764 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Notch4 notch receptor 4 increases expression ISO Bleomycin results in increased expression of NOTCH4 mRNA CTD PMID:36087614 NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072 		JBrowse link
G Nox4 NADPH oxidase 4 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of NOX4 mRNA
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA] 		CTD PMID:35187969 PMID:37307957 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483 		JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP Bleomycin results in increased expression of NPM1 protein CTD PMID:25933445 NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr  X:18,245,740...18,256,024 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity
multiple interactions 		EXP Bleomycin results in decreased activity of NQO1 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of NQO1 protein] 		CTD PMID:26768587 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP Bleomycin results in decreased expression of NR3C1 mRNA CTD PMID:15808516 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression EXP Bleomycin results in decreased expression of NR3C2 mRNA CTD PMID:15808516 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078 		JBrowse link
G Nucb2 nucleobindin 2 increases expression EXP Bleomycin results in increased expression of NUCB2 protein CTD PMID:25933445 NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression
affects response to substance
multiple interactions 		ISO Bleomycin results in increased expression of OGG1 protein
OGG1 protein affects the susceptibility to Bleomycin
OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of OGG1 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of OGG1 protein] 		CTD PMID:35654123 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 increases expression ISO Bleomycin results in increased expression of OSR1 protein CTD PMID:34460027 NCBI chr 6:38,088,688...38,100,010
Ensembl chr 6:38,093,011...38,100,021 		JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression EXP Bleomycin results in increased expression of OSTF1 protein CTD PMID:25933445 NCBI chr 1:225,428,661...225,475,851
Ensembl chr 1:225,428,661...225,541,027 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP Bleomycin results in increased expression of P4HB protein CTD PMID:25933445 NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 increases expression EXP Bleomycin results in increased expression of PABPC1 protein CTD PMID:25933445 NCBI chr 7:69,662,513...69,674,806
Ensembl chr 7:69,663,068...69,675,050 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
increases cleavage
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of PARP1 protein
Bleomycin results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein] 		CTD PMID:15371238 PMID:16317386 PMID:32278510 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression EXP Bleomycin results in increased expression of PDLIM1 protein CTD PMID:25933445 NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression EXP Bleomycin results in increased expression of PDLIM5 protein CTD PMID:25933445 NCBI chr 2:233,625,478...233,793,582
Ensembl chr 2:233,628,503...233,793,528 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of PECAM1 protein] CTD PMID:30825431 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Plau plasminogen activator, urokinase increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of PLAU mRNA; Bleomycin results in increased expression of PLAU protein
Bleomycin results in decreased expression of PLAU mRNA; Bleomycin results in decreased expression of PLAU protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU protein] 		CTD PMID:25648892 PMID:35716765 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of PLAUR mRNA; Bleomycin results in decreased expression of PLAUR protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR protein] 		CTD PMID:35716765 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130 		JBrowse link
G Pml PML nuclear body scaffold multiple interactions
increases expression 		ISO arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] CTD PMID:24762191 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083 		JBrowse link
G Pnp purine nucleoside phosphorylase decreases expression EXP Bleomycin results in decreased expression of PNP protein CTD PMID:25933445 NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162 		JBrowse link
G Podxl podocalyxin-like decreases expression EXP Bleomycin results in decreased expression of PODXL protein CTD PMID:25933445 NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789 		JBrowse link
G Polb DNA polymerase beta decreases response to substance ISO POLB results in decreased susceptibility to Bleomycin CTD PMID:21251944 NCBI chr16:76,081,903...76,105,174
Ensembl chr16:76,081,864...76,108,180 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases response to substance 		ISO PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]
PPARA protein results in decreased susceptibility to Bleomycin 		CTD PMID:16317386 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of PPARG mRNA; Bleomycin results in decreased expression of PPARG protein
lenabasum inhibits the reaction [Bleomycin results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA]
Berberine inhibits the reaction [Bleomycin binds to PPARG protein] 		CTD PMID:19147827 PMID:27153807 PMID:29408570 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppfia4 PTPRF interacting protein alpha 4 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA] CTD PMID:30825431 NCBI chr13:48,305,844...48,354,329
Ensembl chr13:48,305,848...48,354,279 		JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP Bleomycin results in increased expression of PPIA protein CTD PMID:25933445 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression EXP Bleomycin results in decreased expression of PRDX2 protein CTD PMID:25933445 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression EXP Bleomycin results in decreased expression of PRDX6 protein CTD PMID:25933445 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657 		JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein decreases expression EXP Bleomycin results in decreased expression of PRELP protein CTD PMID:25933445 NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324 		JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 1:205,394,248...205,406,525
Ensembl chr 1:205,393,746...205,411,651 		JBrowse link
G Psme1 proteasome activator subunit 1 increases expression EXP Bleomycin results in increased expression of PSME1 protein CTD PMID:25933445 NCBI chr15:33,038,962...33,041,849
Ensembl chr15:33,038,597...33,041,848 		JBrowse link
G Psme2 proteasome activator subunit 2 decreases expression EXP Bleomycin results in decreased expression of PSME2 protein CTD PMID:25933445 NCBI chr15:33,048,452...33,053,055
Ensembl chr15:33,048,457...33,053,102 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA] CTD PMID:30825431 NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression EXP Bleomycin results in increased expression of PTBP1 protein CTD PMID:25933445 NCBI chr 7:10,493,199...10,502,957
Ensembl chr 7:10,493,200...10,502,957 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
decreases expression 		ISO ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN protein]
Bleomycin results in decreased expression of PTEN mRNA; Bleomycin results in decreased expression of PTEN protein 		CTD PMID:29408570 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptgdr prostaglandin D2 receptor increases expression ISO Bleomycin results in increased expression of PTGDR mRNA CTD PMID:20719937 NCBI chr15:19,790,499...19,797,873
Ensembl chr15:19,790,499...19,797,873 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of PTGS2 mRNA; Bleomycin results in increased expression of PTGS2 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of PTGS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of PTGS2 mRNA] 		CTD PMID:26526764 PMID:27704718 PMID:32828905 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptms parathymosin increases expression EXP Bleomycin results in increased expression of PTMS protein CTD PMID:25933445 NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAB1B protein CTD PMID:25933445 NCBI chr 1:211,835,133...211,843,408
Ensembl chr 1:211,835,073...211,843,337
Ensembl chr  X:211,835,073...211,843,337 		JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA] CTD PMID:30825431 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of RAD51AP1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA] 		CTD PMID:30825431 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680 		JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Bleomycin results in increased expression of RALB protein CTD PMID:25933445 NCBI chr13:33,140,834...33,176,997
Ensembl chr13:33,140,835...33,176,998 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAP1B protein CTD PMID:25933445 NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:55,308,922...55,342,217 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
decreases expression
increases phosphorylation
increases activity 		ISO
EXP 		Calcitriol inhibits the reaction [Bleomycin results in increased expression of RELA protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of RELA mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of RELA protein modified form]; methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Berberine inhibits the reaction [Bleomycin affects the localization of and results in increased expression of RELA protein]; Bleomycin affects the localization of and results in increased expression of RELA protein; thymoquinone inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Bleomycin results in increased expression of RELA mRNA; Bleomycin results in increased expression of RELA protein; Bleomycin results in increased expression of RELA protein modified form
Bleomycin results in decreased expression of RELA mRNA
Bleomycin results in increased phosphorylation of RELA protein
Ephedrine inhibits the reaction [Bleomycin results in increased phosphorylation of RELA protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased activity of RELA protein] 		CTD PMID:21575650 PMID:22982510 PMID:23523906 PMID:26520185 PMID:28299617 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO Bleomycin results in decreased expression of RELB mRNA CTD PMID:29720568 NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420 		JBrowse link
G Robo1 roundabout guidance receptor 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of ROBO1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA] 		CTD PMID:30825431 NCBI chr11:24,067,869...25,108,694
Ensembl chr11:24,067,878...25,108,694 		JBrowse link
G Rpl12 ribosomal protein L12 increases expression EXP Bleomycin results in increased expression of RPL12 protein CTD PMID:25933445 NCBI chr 3:36,661,940...36,664,314
Ensembl chr 3:36,661,939...36,664,306 		JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP Bleomycin results in increased expression of RPL13 protein CTD PMID:25933445 NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059 		JBrowse link
G Rpl4 ribosomal protein L4 increases expression EXP Bleomycin results in increased expression of RPL4 protein CTD PMID:25933445 NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788 		JBrowse link
G Rpl5 ribosomal protein L5 increases expression EXP Bleomycin results in increased expression of RPL5 protein CTD PMID:25933445 NCBI chr14:1,988,792...1,995,236
Ensembl chr14:1,988,793...1,995,225 		JBrowse link
G Rpl6 ribosomal protein L6 affects expression EXP Bleomycin affects the expression of RPL6 protein CTD PMID:25933445 NCBI chr12:41,008,142...41,012,756
Ensembl chr12:41,008,142...41,025,733 		JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP Bleomycin results in increased expression of RPS3A1 protein CTD PMID:25933445 NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP Bleomycin results in increased expression of S100A11 protein CTD PMID:25933445 NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression
multiple interactions 		EXP Bleomycin results in increased expression of S100A4 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of S100A4 protein] 		CTD PMID:25933445 PMID:31706003 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837 		JBrowse link
G S100a6 S100 calcium binding protein A6 affects expression EXP Bleomycin affects the expression of S100A6 protein CTD PMID:25933445 NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Bleomycin results in increased expression of S100A8 protein CTD PMID:25933445 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein CTD PMID:29033951 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions
increases expression 		ISO S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA] CTD PMID:29033951 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197 		JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 multiple interactions
affects response to substance 		ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein; [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] CTD PMID:29033951 NCBI chr 8:28,062,841...28,068,013
Ensembl chr 8:28,061,752...28,068,389 		JBrowse link
G Scarna15 small Cajal body-specific RNA 15 affects expression EXP Bleomycin affects the expression of SCARNA15 mRNA CTD PMID:25933445 NCBI chr 1:144,893,856...144,893,919
Ensembl chr 1:144,893,795...144,893,921 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 decreases expression EXP Bleomycin results in decreased expression of SCGB1A1 protein CTD PMID:25933445 NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:215,406,138...215,409,686 		JBrowse link
G Scp2 sterol carrier protein 2 increases expression EXP Bleomycin results in increased expression of SCP2 protein CTD PMID:25933445 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043 		JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression EXP Bleomycin results in increased expression of SCPEP1 protein CTD PMID:25933445 NCBI chr10:74,200,491...74,230,107
Ensembl chr10:74,200,491...74,230,241 		JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA] CTD PMID:30825431 NCBI chr20:6,200,891...6,232,848
Ensembl chr20:6,200,178...6,233,051 		JBrowse link
G Sec14l3 SEC14-like lipid binding 3 decreases expression EXP Bleomycin results in decreased expression of SEC14L3 protein CTD PMID:25933445 NCBI chr14:83,168,154...83,181,240
Ensembl chr14:83,168,208...83,179,654 		JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression EXP Bleomycin results in decreased expression of SELENBP1 protein CTD PMID:25933445 NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295 		JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA] CTD PMID:30825431 NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031 		JBrowse link
G Serpine1 serpin family E member 1 increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of SERPINE1 mRNA; Bleomycin results in increased expression of SERPINE1 protein
Bleomycin results in decreased expression of SERPINE1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 protein]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein] 		CTD PMID:29175452 PMID:30825431 PMID:35716765 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions
increases expression 		EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of SERPINH1 protein] CTD PMID:23656969 PMID:25933445 NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Bleomycin results in increased expression of SFRP1 mRNA CTD PMID:26345256 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736 		JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions
decreases expression
increases expression 		ISO
EXP 		[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]
Bleomycin results in decreased expression of SFTPA1 mRNA
Bleomycin results in increased expression of SFTPA1 protein 		CTD PMID:14617519 PMID:15782499 PMID:25933445 NCBI chr16:17,042,264...17,045,770
Ensembl chr16:17,042,255...17,045,769 		JBrowse link
G Sftpb surfactant protein B decreases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of SFTPB mRNA
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein 		CTD PMID:15782499 PMID:33647319 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646 		JBrowse link
G Sftpc surfactant protein C decreases expression EXP Bleomycin results in decreased expression of SFTPC mRNA; Bleomycin results in decreased expression of SFTPC protein CTD PMID:34425168 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475 		JBrowse link
G Sftpd surfactant protein D increases expression
increases metabolic processing
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of SFTPD mRNA; Bleomycin results in increased expression of SFTPD protein
Bleomycin results in increased metabolism of SFTPD protein
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Bleomycin promotes the reaction [SFTPD protein binds to SFTPD protein binds to SFTPD protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased metabolism of SFTPD protein] 		CTD PMID:11880309 PMID:25933445 PMID:26526764 PMID:33647319 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,080,567...17,094,036 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SIRT1 mRNA; Bleomycin results in decreased expression of SIRT1 protein
resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 protein] 		CTD PMID:25707573 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression EXP Bleomycin results in increased expression of SLC12A1 mRNA CTD PMID:15808516 NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Bleomycin results in increased expression of SLC1A2 mRNA CTD PMID:15808516 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression EXP Bleomycin results in decreased expression of SLC25A4 protein CTD PMID:25933445 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases expression EXP Bleomycin results in decreased expression of SLC25A5 protein CTD PMID:25933445 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:120,897,563...120,900,688 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 increases expression EXP Bleomycin results in increased expression of SLC6A12 mRNA CTD PMID:15808516 NCBI chr 4:156,257,518...156,275,870
Ensembl chr 4:156,254,208...156,275,879 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SLC6A15 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA] 		CTD PMID:30825431 NCBI chr 7:40,439,607...40,493,788
Ensembl chr 7:40,439,658...40,493,786 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SLC7A1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA] 		CTD PMID:30825431 NCBI chr12:11,664,488...11,740,030
Ensembl chr12:11,664,399...11,740,030 		JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 increases response to substance
multiple interactions 		ISO SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin
[SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA] 		CTD PMID:32828905 NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:112,467,160...112,551,921 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression
multiple interactions 		ISO Bleomycin results in increased expression of SLPI mRNA; Bleomycin results in increased expression of SLPI protein
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA] 		CTD PMID:26345256 PMID:30825431 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822 		JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions
increases expression 		ISO Bleomycin results in increased phosphorylation of SMAD2 protein
camostat inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]
yupingfeng inhibits the reaction [Bleomycin results in increased expression of SMAD2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein] 		CTD PMID:26599507 PMID:31884830 PMID:32032644 PMID:35187969 PMID:37898439 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases expression
increases phosphorylation 		EXP
ISO 		Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA]
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein] 		CTD PMID:26093215 PMID:27704718 PMID:31884830 PMID:32032644 PMID:35187969 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Smad7 SMAD family member 7 decreases expression
increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of SMAD7 mRNA
Bleomycin results in increased expression of SMAD7 mRNA
MIR182 affects the reaction [Bleomycin results in decreased expression of SMAD7 protein]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] 		CTD PMID:26093215 PMID:29033951 PMID:31884830 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A increases phosphorylation ISO Bleomycin results in increased phosphorylation of SMC1A protein CTD PMID:24933654 NCBI chr  X:24,582,732...24,627,462
Ensembl chr  X:24,582,690...24,627,462 		JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO Bleomycin results in decreased expression of SMIM14 mRNA CTD PMID:33770205 NCBI chr14:43,136,754...43,180,622
Ensembl chr14:43,136,867...43,183,416 		JBrowse link
G Smtn smoothelin decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SMTN mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA] 		CTD PMID:30825431 NCBI chr14:82,622,223...82,644,525
Ensembl chr14:82,621,375...82,644,514 		JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression EXP Bleomycin results in decreased expression of SNORA58 mRNA CTD PMID:25933445 NCBI chr 6:112,811,875...112,811,950 JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Bleomycin results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
decreases expression
decreases activity 		ISO
EXP 		Bleomycin results in increased expression of SOD1 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]
Bleomycin results in decreased expression of SOD1 protein
Bleomycin results in decreased activity of SOD1 protein 		CTD PMID:8317554 PMID:25933445 PMID:30106319 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases activity 		ISO
EXP 		Bleomycin results in increased expression of SOD2 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in decreased activity of SOD2 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of SOD2 protein] 		CTD PMID:8317554 PMID:26768587 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sparc secreted protein acidic and cysteine rich increases response to substance ISO SPARC protein results in increased susceptibility to Bleomycin CTD PMID:19446018 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268 		JBrowse link
G Sparcl1 SPARC like 1 decreases expression EXP Bleomycin results in decreased expression of SPARCL1 protein CTD PMID:25933445 NCBI chr14:5,937,484...5,968,532
Ensembl chr14:5,914,535...5,969,120 		JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex increases expression ISO Bleomycin results in increased expression of SPC25 mRNA CTD PMID:36087614 NCBI chr 3:74,337,872...74,396,825
Ensembl chr 3:74,383,548...74,396,718 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Bleomycin results in increased expression of SPP1 mRNA; Bleomycin results in increased expression of SPP1 protein CTD PMID:26345256 PMID:29175452 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression EXP Bleomycin results in decreased expression of SPTAN1 protein CTD PMID:25933445 NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Bleomycin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765 		JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression EXP Bleomycin results in decreased expression of SSTR1 mRNA CTD PMID:15808516 NCBI chr 6:81,567,237...81,571,759
Ensembl chr 6:81,566,850...81,571,992 		JBrowse link
G Sstr2 somatostatin receptor 2 decreases expression EXP Bleomycin results in decreased expression of SSTR2 mRNA CTD PMID:15808516 NCBI chr10:99,163,353...99,170,519
Ensembl chr10:99,162,740...99,183,863 		JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression EXP Bleomycin results in decreased expression of SSTR3 mRNA CTD PMID:15808516 NCBI chr 7:111,973,049...111,980,250
Ensembl chr 7:111,972,811...111,997,368 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ST14 protein CTD PMID:26599507 NCBI chr 8:37,798,994...37,839,881
Ensembl chr 8:37,798,995...37,855,652 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression ISO Bleomycin results in decreased expression of ST3GAL5 mRNA CTD PMID:33770205 NCBI chr 4:105,692,840...105,750,774
Ensembl chr 4:105,692,840...105,750,775 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases expression 		ISO honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
decreases response to substance 		ISO STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
STAT6 gene mutant form results in decreased susceptibility to Bleomycin 		CTD PMID:15322207 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Stk11 serine/threonine kinase 11 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of STK11 protein
Soot inhibits the reaction [Bleomycin results in increased expression of STK11 protein] 		CTD PMID:31302203 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
G Stk26 serine/threonine kinase 26 increases expression EXP Bleomycin results in increased expression of PDXK protein CTD PMID:25933445 NCBI chr  X:135,195,176...135,259,994
Ensembl chr  X:135,195,204...135,259,993 		JBrowse link
G Stmn1 stathmin 1 increases expression EXP Bleomycin results in increased expression of STMN1 protein CTD PMID:25933445 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b increases expression EXP Bleomycin results in increased expression of SV2B mRNA CTD PMID:15808516 NCBI chr 1:138,388,268...138,562,635
Ensembl chr 1:138,388,266...138,562,258 		JBrowse link
G Tacr2 tachykinin receptor 2 decreases expression EXP Bleomycin results in decreased expression of TACR2 mRNA CTD PMID:15808516 NCBI chr20:30,751,645...30,766,181
Ensembl chr20:30,751,557...30,766,180 		JBrowse link
G Tagln transgelin increases expression EXP Bleomycin results in increased expression of TAGLN protein CTD PMID:25933445 NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563 		JBrowse link
G Tagln2 transgelin 2 increases expression EXP Bleomycin results in increased expression of TAGLN2 protein CTD PMID:25933445 NCBI chr13:87,499,350...87,506,328
Ensembl chr13:87,499,394...87,506,330 		JBrowse link
G Taldo1 transaldolase 1 decreases expression EXP Bleomycin results in decreased expression of TALDO1 protein CTD PMID:25933445 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535 		JBrowse link
G Tapbp TAP binding protein affects response to substance ISO TAPBP protein affects the susceptibility to Bleomycin CTD PMID:38992170 NCBI chr20:4,958,821...4,967,958
Ensembl chr20:4,959,926...4,971,834 		JBrowse link
G Tbx21 T-box transcription factor 21 increases expression ISO Bleomycin results in increased expression of TBX21 mRNA CTD PMID:29033951 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B decreases expression ISO Bleomycin results in decreased expression of TENT4B mRNA CTD PMID:33770205 NCBI chr19:34,984,244...35,042,423
Ensembl chr19:34,980,296...35,042,399 		JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance ISO TERT gene mutant form results in decreased susceptibility to Bleomycin CTD PMID:18008008 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tf transferrin increases expression EXP Bleomycin results in increased expression of TF protein CTD PMID:25933445 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases secretion
increases expression 		ISO
EXP 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of TGFB1 mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of TGFB1 mRNA; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; bufotalin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; camostat inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; MIR182 affects the reaction [Bleomycin results in increased expression of TGFB1 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Berberine inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
Bleomycin results in increased secretion of TGFB1 protein
Bleomycin results in increased expression of TGFB1 mRNA; Bleomycin results in increased expression of TGFB1 protein
yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein] 		CTD PMID:14609568 PMID:15541506 PMID:16115399 PMID:16314464 PMID:17035056 More... NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression EXP Bleomycin results in decreased expression of TGFB1I1 protein CTD PMID:25933445 NCBI chr 1:192,258,992...192,265,903
Ensembl chr 1:192,258,598...192,265,903 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA] CTD PMID:28434932 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TGFB3 mRNA
CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] 		CTD PMID:28434932 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions
increases expression 		ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA] 		CTD PMID:28434932 PMID:28726637 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA] CTD PMID:28434932 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 increases expression ISO Bleomycin results in increased expression of TGIF2 mRNA CTD PMID:36087614 NCBI chr 3:165,791,101...165,808,669
Ensembl chr 3:165,793,480...165,808,666 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Bleomycin results in increased expression of THBS1 mRNA CTD PMID:29720568 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Thbs2 thrombospondin 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of THBS2 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of THBS2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of THBS2 protein] 		CTD PMID:30825431 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918 		JBrowse link
G Thop1 thimet oligopeptidase 1 decreases expression ISO Bleomycin results in decreased expression of THOP1 protein CTD PMID:29733421 NCBI chr 7:9,283,617...9,295,957
Ensembl chr 7:9,283,617...9,295,957 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Bleomycin results in decreased expression of THRB mRNA CTD PMID:15808516 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TIMP1 mRNA; Bleomycin results in increased expression of TIMP1 protein
Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein] 		CTD PMID:26345256 PMID:28300665 PMID:32032644 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tlr1 toll-like receptor 1 decreases expression ISO Bleomycin results in decreased expression of TLR1 mRNA CTD PMID:29720568 NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,740,379...43,756,243 		JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 decreases expression ISO Bleomycin results in decreased expression of TMCC3 mRNA CTD PMID:33770205 NCBI chr 7:30,781,452...31,058,888
Ensembl chr 7:30,897,991...31,058,889 		JBrowse link
G Tmem250 transmembrane protein 250 increases expression ISO Bleomycin results in increased expression of TMEM250 mRNA CTD PMID:33770205 NCBI chr 3:29,360,770...29,364,756
Ensembl chr 3:29,360,770...29,364,462 		JBrowse link
G Tmem87a transmembrane protein 87A increases expression ISO Bleomycin results in increased expression of TMEM87A mRNA CTD PMID:33770205 NCBI chr 3:127,761,490...127,807,314
Ensembl chr 3:127,761,490...127,807,314 		JBrowse link
G Tnc tenascin C increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TNC mRNA; Bleomycin results in increased expression of TNC protein
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TNC protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TNC protein] 		CTD PMID:26345256 PMID:30825431 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
affects response to substance 		ISO
EXP 		[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]; Ephedrine inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; Ozone inhibits the reaction [[Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TNF protein]; [SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of TNF protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of TNF protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of TNF protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of TNF protein]
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of TNF protein; Berberine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of TNF protein]
Bleomycin results in increased expression of TNF mRNA; Bleomycin results in increased expression of TNF protein 		CTD PMID:8317554 PMID:8473757 PMID:11350791 PMID:12003776 PMID:14609568 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases response to substance
increases expression 		ISO TNFRSF1A results in increased susceptibility to Bleomycin
Bleomycin results in increased expression of TNFRSF1A mRNA 		CTD PMID:12003776 PMID:36087614 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression
increases response to substance 		EXP
ISO 		Bleomycin results in increased expression of TNFRSF1B protein
TNFRSF1B results in increased susceptibility to Bleomycin 		CTD PMID:12003776 PMID:15371238 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Bleomycin results in decreased expression of TNFSF11 mRNA CTD PMID:29720568 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression ISO Bleomycin results in increased expression of TNFSF4 mRNA CTD PMID:36087614 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Tp53 tumor protein p53 increases expression
increases response to substance
increases phosphorylation
multiple interactions 		ISO Bleomycin results in increased expression of TRP53 protein
TP53 protein results in increased susceptibility to Bleomycin
Bleomycin results in increased phosphorylation of TP53 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA] 		CTD PMID:9683175 PMID:20135637 PMID:24933654 PMID:26800624 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP Bleomycin results in increased expression of TPM1 protein CTD PMID:25933445 NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468 		JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP Bleomycin results in increased expression of TPM3 protein CTD PMID:25933445 NCBI chr 2:177,812,534...177,842,661
Ensembl chr 2:177,814,883...177,842,660 		JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP Bleomycin results in increased expression of TPM4 protein CTD PMID:25933445 NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494 		JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 decreases expression EXP Bleomycin results in decreased expression of TPPP3 protein CTD PMID:25933445 NCBI chr19:50,255,809...50,259,655
Ensembl chr19:50,255,810...50,259,489 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases expression
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of TRAF2 protein
Bleomycin results in increased expression of TRAF2 mRNA 		CTD PMID:15371238 PMID:36087614 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO Calcitriol inhibits the reaction [Bleomycin results in increased phosphorylation of ACT1 protein] CTD PMID:26520185 NCBI chr20:44,565,992...44,609,240
Ensembl chr20:44,517,242...44,609,618 		JBrowse link
G Trim28 tripartite motif-containing 28 increases phosphorylation ISO Bleomycin results in increased phosphorylation of TRIM28 protein CTD PMID:24933654 NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:82,724,838...82,731,572 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein] CTD PMID:26600069 NCBI chr20:10,703,190...10,752,795
Ensembl chr20:10,704,482...10,752,802 		JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of TSHR mRNA CTD PMID:15808516 NCBI chr 6:116,072,321...116,206,009
Ensembl chr 6:116,072,281...116,206,010 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Bleomycin results in decreased expression of TUBA1C protein CTD PMID:25933445 NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP
ISO 		Bleomycin results in decreased expression of TUBB2A protein
Bleomycin results in decreased expression of TUBB2A mRNA 		CTD PMID:25933445 PMID:33770205 NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,983,387...31,006,838 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Bleomycin results in decreased expression of TUBB4B protein CTD PMID:25933445 NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:28,435,148...28,439,719 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO Bleomycin results in increased expression of TWIST1 protein CTD PMID:37126650 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965 		JBrowse link
G Tymp thymidine phosphorylase increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TYMP protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of TYMP protein] 		CTD PMID:30825431 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO Bleomycin results in decreased expression of UGCG mRNA CTD PMID:33770205 NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:78,828,006...78,860,417 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of ULK1 protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of ULK1 protein modified form] 		CTD PMID:31302203 NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression EXP Bleomycin results in decreased expression of UQCRC1 protein CTD PMID:25933445 NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:118,468,200...118,479,964 		JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein increases expression EXP Bleomycin results in increased expression of UQCRHL protein CTD PMID:25933445 NCBI chr 5:134,782,687...134,790,882
Ensembl chr 5:134,782,255...134,790,926 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA] CTD PMID:30825431 NCBI chr 9:2,248,856...2,295,905
Ensembl chr 9:2,248,914...2,296,922 		JBrowse link
G Vcl vinculin decreases expression EXP Bleomycin results in decreased expression of VCL protein CTD PMID:25933445 NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,315,069...3,405,163 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Bleomycin results in increased expression of VEGFA mRNA CTD PMID:26093215 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfb vascular endothelial growth factor B increases expression
multiple interactions 		ISO Bleomycin results in increased expression of VEGFB protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of VEGFB protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VEGFB protein] 		CTD PMID:30825431 NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:213,600,966...213,607,152 		JBrowse link
G Vim vimentin increases expression
decreases expression
affects expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of VIM protein
Bleomycin results in decreased expression of VIM mRNA
Bleomycin affects the expression of VIM protein
Bleomycin results in increased expression of VIM mRNA; Bleomycin results in increased expression of VIM protein
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of VIM protein]
Ephedrine inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased expression of VIM protein] 		CTD PMID:25933445 PMID:34425168 PMID:35267148 PMID:35472619 PMID:37126650 More... NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vwf von Willebrand factor multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of VWF protein] CTD PMID:30825431 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
G Wif1 Wnt inhibitory factor 1 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA] CTD PMID:30825431 NCBI chr 7:58,433,326...58,503,853
Ensembl chr 7:58,384,643...58,503,852 		JBrowse link
G Wnt1 Wnt family member 1 increases expression ISO Bleomycin results in increased expression of WNT1 mRNA CTD PMID:36087614 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:131,817,558...131,821,605 		JBrowse link
G Wnt10a Wnt family member 10A increases expression ISO Bleomycin results in increased expression of WNT10A mRNA CTD PMID:36087614 NCBI chr 9:83,798,594...83,811,060
Ensembl chr 9:83,798,594...83,811,067 		JBrowse link
G Wnt9a Wnt family member 9A increases expression ISO Bleomycin results in increased expression of WNT9A mRNA CTD PMID:36087614 NCBI chr10:44,593,691...44,620,682
Ensembl chr10:44,593,691...44,620,682 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 affects response to substance
decreases response to substance 		ISO XRCC1 gene polymorphism affects the susceptibility to Bleomycin
XRCC1 results in decreased susceptibility to Bleomycin 		CTD PMID:12082022 PMID:20705543 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Bleomycin CTD PMID:12384553 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase decreases expression ISO Bleomycin results in decreased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 9:120,646,657...120,753,880
Ensembl chr 9:120,646,838...120,746,441 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression EXP Bleomycin results in decreased expression of YWHAB protein CTD PMID:25933445 NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854 		JBrowse link
G Zfx zinc finger protein X-linked increases expression ISO Bleomycin results in increased expression of ZFX mRNA CTD PMID:33770205 NCBI chr  X:62,798,483...62,847,068
Ensembl chr  X:62,798,483...62,875,309 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20849
    role 20820
      biological role 20805
        antimicrobial agent 18570
          bleomycin 739
            bleomycin A2 664
Path 2
Term Annotations click to browse term
  CHEBI ontology 20849
    subatomic particle 20847
      composite particle 20860
        hadron 20847
          baryon 20860
            nucleon 20847
              atomic nucleus 20847
                atom 20860
                  main group element atom 20781
                    p-block element atom 20768
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20207
                              organochalcogen compound 19905
                                organooxygen compound 19807
                                  carbon oxoacid 19157
                                    carboxylic acid 19154
                                      carboacyl group 18089
                                        univalent carboacyl group 18071
                                          carbamoyl group 17906
                                            carboxamide 17925
                                              peptide 11664
                                                peptide antibiotic 2758
                                                  chelate-forming peptide 739
                                                    bleomycin 739
                                                      bleomycin A2 664
paths to the root