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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bifonazole
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Accession:CHEBI:31286 term browser browse the term
Definition:A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.
Synonyms:exact_synonym: rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole
 related_synonym: (+-)-1-(p,alpha-Diphenylbenzyl)imidazole;   (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole;   (RS)-bifonazole;   1-((4-Biphenylyl)phenylmethyl)-1H-imidazole;   1-(alpha-(4-Biphenylyl)benzyl)imidazole;   Formula=C22H18N2;   Mycospor;   bifonazol;   bifonazolum;   rac-bifonazole;   racemic bifonazole
 xref: CAS:60628-96-8;   DrugBank:DB04794;   HMDB:HMDB0015583;   KEGG:D01775
 xref_mesh: MESH:C036596
 xref: PMID:21746947;   PMID:23066185;   PMID:23283047;   PMID:23467055;   PMID:23586591;   PMID:24215461;   PMID:24849495;   Reaxys:618427;   Wikipedia:Bifonazole


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bifonazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO bifonazole results in decreased activity of CYP19A1 protein CTD PMID:15554355 PMID:24496634 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO bifonazole results in decreased activity of CYP3A4 protein CTD PMID:15135088 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO bifonazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19901
    chemical entity 19899
      chemical substance 14414
        mixture 13731
          racemate 12108
            bifonazole 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    p-block element atom 19838
                      carbon group element atom 19778
                        carbon atom 19775
                          organic molecular entity 19775
                            organic molecule 19728
                              organic cyclic compound 19519
                                organic heterocyclic compound 18898
                                  heteroarene 17175
                                    monocyclic heteroarene 15000
                                      azole 14520
                                        diazole 10784
                                          imidazoles 10234
                                            1-[biphenyl-4-yl(phenyl)methyl]imidazole 3
                                              (R)-bifonazole 3
                                                bifonazole 3
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