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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benserazide hydrochloride
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Accession:CHEBI:31262 term browser browse the term
Definition:A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone.
Synonyms:exact_synonym: 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
 related_synonym: 2'-(2,3,4-trihydroxybenzyl)-DL-serinohydrazide monohydrochloride;   3-hydroxy-1-oxo-1-[2-(2,3,4-trihydroxybenzyl)hydrazinyl]propan-2-aminium chloride;   DL-serine 2-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride;   Formula=C10H16ClN3O5;   InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H;   InChIKey=ULFCBIUXQQYDEI-UHFFFAOYSA-N;   Ro 4-4602/001;   SMILES=Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O;   benserazide HCl
 xref: CAS:14919-77-8;   KEGG:D01653;   Reaxys:6494463



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Term Annotations click to browse term
  CHEBI ontology 19899
    role 19870
      biological role 19868
        pharmacological role 19105
          neurotransmitter agent 16812
            dopaminergic agent 5507
              benserazide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19836
                    p-block element atom 19836
                      halogen 18710
                        chlorine atom 18488
                          chlorine molecular entity 18488
                            elemental chlorine 9025
                              monoatomic chlorine 9010
                                chloride 9010
                                  chloride salt 9010
                                    organic chloride salt 1109
                                      hydrochloride 738
                                        benserazide hydrochloride 0
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