Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:aripiprazole
go back to main search page
Accession:CHEBI:31236 term browser browse the term
Definition:An N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders.
Synonyms:exact_synonym: 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
 related_synonym: 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone;   7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one;   7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one;   Abilify;   Abilify Discmelt;   Abilify Maintena;   Abilify MyCite;   Abilitat;   Arpizol;   Asprito;   Discmelt;   Formula=C23H27Cl2N3O2;   InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29);   InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N;   OPC 14597;   OPC-31;   Pripiprazole;   SMILES=ClC1=C(Cl)C(=CC=C1)N1CCN(CCCCOC2=CC=C3CCC(=O)NC3=C2)CC1;   aripiprazol;   aripiprazolum
 alt_id: MESH:D000068180
 xref: CAS:129722-12-9;   Chemspider:54790;   DrugBank:DB01238;   Drug_Central:242;   FooDB:FDB004879;   HMDB:HMDB0005042;   KEGG:C12564;   KEGG:D01164;   LINCS:LSM-5776
 xref_mesh: MESH:C094645
 xref: PDBeChem:9SC;   PMID:12063084;   PMID:12784105;   PMID:14998222;   PMID:15019558;   PMID:15189766;   PMID:15257633;   PMID:15825673;   PMID:16401666;   PMID:16508892;   PMID:16554739;   PMID:16648324;   PMID:16880478;   PMID:17115868;   PMID:17472545;   PMID:17501690;   PMID:18021764;   PMID:18646161;   PMID:18720421;   PMID:18765484;   PMID:18788833;   PMID:19412463;   PMID:19956463;   PMID:20201815;   PMID:30292748;   PMID:30411049;   PMID:30856161;   PMID:31152368;   PMID:31320322;   PMID:32891516;   PMID:33064050;   PMID:33347031;   Patent:EP367141;   Patent:US5006528;   Wikipedia:Aripiprazole


show annotations for term's descendants           Sort by:
aripiprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain decreases expression EXP Aripiprazole results in decreased expression of ACADL mRNA CTD PMID:17868501 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ADORA2A mRNA CTD PMID:31476115 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B decreases expression EXP Aripiprazole results in decreased expression of ARPC1B mRNA CTD PMID:17868501 NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of BCL10 mRNA CTD PMID:31476115 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of BCL2L1 mRNA CTD PMID:31476115 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of BCL6 mRNA CTD PMID:31476115 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of BID mRNA CTD PMID:31476115 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G C1r complement C1r multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in decreased expression of C1R mRNA] CTD PMID:31476115 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C2 complement C2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of C2 mRNA CTD PMID:31476115 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cbx7 chromobox 7 decreases expression
increases expression		 EXP Aripiprazole results in decreased expression of CBX7 mRNA
Aripiprazole results in increased expression of CBX7 mRNA		 CTD PMID:17868501 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL19 mRNA CTD PMID:31476115 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL2 mRNA CTD PMID:31476115 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL20 mRNA CTD PMID:31476115 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of CCL22 mRNA] CTD PMID:31476115 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL3 mRNA CTD PMID:31476115 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL4 mRNA CTD PMID:31476115 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL5 mRNA CTD PMID:31476115 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCR3 mRNA CTD PMID:31476115 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD274 mRNA CTD PMID:31476115 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd33 CD33 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD33 mRNA CTD PMID:31476115 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD44 mRNA CTD PMID:31476115 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd70 Cd70 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD70 mRNA CTD PMID:31476115 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715 		JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD83 mRNA CTD PMID:31476115 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cdh5 cadherin 5 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of CDH5 mRNA] CTD PMID:31476115 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CDKN1A mRNA CTD PMID:31476115 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CEBPB mRNA CTD PMID:31476115 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfb complement factor B multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CFB mRNA CTD PMID:31476115 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cldn5 claudin 5 decreases expression EXP Aripiprazole results in decreased expression of CLDN5 mRNA CTD PMID:17868501 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cnr1 cannabinoid receptor 1 increases expression EXP Aripiprazole results in increased expression of CNR1 mRNA CTD PMID:17868501 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Aripiprazole results in increased expression of COMT mRNA CTD PMID:17868501 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP Aripiprazole results in increased expression of CREB1 mRNA CTD PMID:26894264 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Creb5 cAMP responsive element binding protein 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CREB5 mRNA CTD PMID:31476115 NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325 		JBrowse link
G Crebbp CREB binding protein decreases expression EXP Aripiprazole results in decreased expression of CREBBP mRNA CTD PMID:17868501 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crmp1 collapsin response mediator protein 1 increases expression EXP Aripiprazole results in increased expression of CRMP1 mRNA CTD PMID:17868501 NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF1 mRNA CTD PMID:31476115 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF2 mRNA CTD PMID:31476115 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF3 mRNA CTD PMID:31476115 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CX3CL1 mRNA CTD PMID:31476115 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA CTD PMID:31476115 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCL2 mRNA CTD PMID:31476115 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA CTD PMID:31476115 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCR5 mRNA CTD PMID:31476115 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCR6 mRNA CTD PMID:31476115 NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CYBB mRNA CTD PMID:31476115 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CYLD mRNA CTD PMID:31476115 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Aripiprazole results in decreased expression of DDR2 mRNA CTD PMID:17868501 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx50 DExD-box helicase 50 increases expression EXP Aripiprazole results in increased expression of DDX50 mRNA CTD PMID:17868501 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152 		JBrowse link
G Dnal4 dynein, axonemal, light chain 4 decreases expression EXP Aripiprazole results in decreased expression of DNAL4 mRNA CTD PMID:17868501 NCBI chr 7:111,312,424...111,325,283
Ensembl chr 7:111,312,427...111,325,283
Ensembl chr20:111,312,427...111,325,283 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha increases expression EXP Aripiprazole results in increased expression of DNMT3A mRNA CTD PMID:17868501 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP
ISO		 [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine CTD PMID:17069544 PMID:17327886 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of DUSP4 mRNA CTD PMID:31476115 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of DUSP6 mRNA CTD PMID:31476115 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of EBI3 mRNA] CTD PMID:31476115 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544 		JBrowse link
G Egr1 early growth response 1 increases expression EXP Aripiprazole results in increased expression of EGR1 mRNA; Aripiprazole results in increased expression of EGR1 protein CTD PMID:17868501 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 increases expression EXP Aripiprazole results in increased expression of EGR2 mRNA CTD PMID:17868501 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr4 early growth response 4 increases expression EXP Aripiprazole results in increased expression of EGR4 mRNA CTD PMID:17868501 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ELANE mRNA CTD PMID:31476115 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Elavl2 ELAV like RNA binding protein 2 increases expression EXP Aripiprazole results in increased expression of ELAVL2 mRNA CTD PMID:17868501 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ETS1 mRNA CTD PMID:31476115 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Exoc2 exocyst complex component 2 increases expression EXP Aripiprazole results in increased expression of EXOC2 mRNA CTD PMID:17868501 NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of F2RL1 mRNA] CTD PMID:31476115 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 multiple interactions
increases expression		 ISO [Aripiprazole co-treated with Ozone] results in increased expression of FEZ1 mRNA
Aripiprazole results in increased expression of FEZ1 mRNA		 CTD PMID:31476115 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683 		JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Aripiprazole results in decreased expression of FN1 mRNA CTD PMID:31476115 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP Aripiprazole results in increased expression of GABRB1 mRNA CTD PMID:26894264 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression EXP Aripiprazole results in decreased expression of HBEGF mRNA CTD PMID:17868501 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Aripiprazole binds to and affects the activity of HTR1A protein; Aripiprazole binds to and results in increased activity of HTR1A protein CTD PMID:17069544 PMID:21823597 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
decreases response to substance
affects response to substance		 ISO Aripiprazole binds to and results in decreased activity of HTR2A protein; Aripiprazole binds to and results in increased activity of HTR2A protein; Aripiprazole inhibits the reaction [Ketanserin binds to HTR2A protein]
HTR2A gene SNP results in decreased susceptibility to Aripiprazole
HTR2A protein affects the susceptibility to Aripiprazole		 CTD PMID:16314884 PMID:21823597 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions ISO Aripiprazole binds to and affects the activity of HTR2C protein CTD PMID:21823597 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ICAM1 mRNA CTD PMID:31476115 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icam4 intercellular adhesion molecule 4, Landsteiner-Wiener blood group multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ICAM4 mRNA CTD PMID:31476115 NCBI chr 8:19,566,075...19,567,171
Ensembl chr 8:19,566,075...19,567,171 		JBrowse link
G Icoslg inducible T-cell co-stimulator ligand multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ICOSLG mRNA CTD PMID:31476115 NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703 		JBrowse link
G Ifnb1 interferon beta 1 increases expression
multiple interactions		 ISO Aripiprazole results in increased expression of IFNB1 mRNA
Aripiprazole promotes the reaction [Ozone results in increased expression of IFNB1 mRNA]		 CTD PMID:31476115 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of IFNG mRNA CTD PMID:31476115 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IFNGR1 mRNA CTD PMID:31476115 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IKBKE mRNA CTD PMID:31476115 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Il11 interleukin 11 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL11 mRNA CTD PMID:31476115 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1A mRNA CTD PMID:31476115 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1B mRNA CTD PMID:31476115 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1R2 mRNA CTD PMID:31476115 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1RAP mRNA CTD PMID:31476115 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Il1rapl2 interleukin 1 receptor accessory protein-like 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1RAPL2 mRNA CTD PMID:31476115 NCBI chr  X:100,961,509...102,271,753
Ensembl chr  X:100,961,812...102,271,753 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1RL1 mRNA CTD PMID:31476115 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL23A mRNA CTD PMID:31476115 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il24 interleukin 24 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL24 mRNA CTD PMID:31476115 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of IL2RG mRNA CTD PMID:31476115 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il4r interleukin 4 receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL4R mRNA CTD PMID:31476115 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL5 mRNA CTD PMID:31476115 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL6 mRNA; Aripiprazole promotes the reaction [Ozone results in increased expression of IL6 mRNA] CTD PMID:31476115 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il7r interleukin 7 receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL7R mRNA CTD PMID:31476115 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of INPP5D mRNA CTD PMID:31476115 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of IRAK2 mRNA] CTD PMID:31476115 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of IRF8 mRNA CTD PMID:31476115 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression
multiple interactions		 ISO Aripiprazole results in increased expression of ISG20 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of ISG20 mRNA		 CTD PMID:31476115 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ITGA2 mRNA CTD PMID:31476115 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itga5 integrin subunit alpha 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ITGA5 mRNA CTD PMID:31476115 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Aripiprazole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Aripiprazole results in decreased activity of KCNH2 protein		 CTD PMID:21158687 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression EXP Aripiprazole results in increased expression of KCNJ3 mRNA CTD PMID:17868501 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LIF mRNA CTD PMID:31476115 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LRRN3 mRNA CTD PMID:31476115 NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330 		JBrowse link
G Lta lymphotoxin alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LTA mRNA CTD PMID:31476115 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LTB mRNA CTD PMID:31476115 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LYN mRNA CTD PMID:31476115 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Maob monoamine oxidase B increases expression EXP Aripiprazole results in increased expression of MAOB mRNA CTD PMID:17868501 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP Aripiprazole results in increased expression of MAPK6 mRNA CTD PMID:17868501 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of MAPKAPK2 mRNA CTD PMID:31476115 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NFKB1 mRNA CTD PMID:31476115 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of NFKB2 mRNA] CTD PMID:31476115 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NFKBIA mRNA CTD PMID:31476115 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NLRP3 mRNA CTD PMID:31476115 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions
increases expression		 ISO [Aripiprazole co-treated with Ozone] results in increased expression of NOD2 mRNA
Aripiprazole results in increased expression of NOD2 mRNA		 CTD PMID:31476115 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 decreases expression EXP Aripiprazole results in decreased expression of NPDC1 mRNA CTD PMID:17868501 NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NT5E mRNA CTD PMID:31476115 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Ntm neurotrimin decreases expression EXP Aripiprazole results in decreased expression of NTM mRNA CTD PMID:17868501 NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PDCD1LG2 mRNA CTD PMID:31476115 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Pdgfc platelet derived growth factor C multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of PDGFC mRNA CTD PMID:31476115 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 increases expression EXP Aripiprazole results in increased expression of PDP1 mRNA CTD PMID:17868501 NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217 		JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PLAU mRNA CTD PMID:31476115 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PLAUR mRNA CTD PMID:31476115 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of POU2F2 mRNA CTD PMID:31476115 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PRG2 mRNA CTD PMID:31476115 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP Aripiprazole results in increased expression of PRKACA protein CTD PMID:26894264 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PRKCD mRNA CTD PMID:31476115 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prl prolactin multiple interactions
increases secretion
decreases secretion
decreases expression		 ISO
EXP		 Aripiprazole inhibits the reaction [haloperidol decanoate results in increased expression of PRL protein]; Aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein]
Aripiprazole results in increased secretion of PRL protein
Aripiprazole results in decreased secretion of PRL protein
Aripiprazole inhibits the reaction [talipexole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]
Aripiprazole results in decreased expression of PRL protein		 CTD PMID:8613910 PMID:17873694 PMID:19230981 PMID:19519261 PMID:19653986 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prodh proline dehydrogenase decreases expression EXP Aripiprazole results in decreased expression of PRODH mRNA CTD PMID:17868501 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression EXP Aripiprazole results in increased expression of PSMC6 mRNA CTD PMID:17868501 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PTGS2 mRNA CTD PMID:31476115 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of PYCARD mRNA CTD PMID:31476115 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression EXP Aripiprazole results in increased expression of RAB3A mRNA CTD PMID:17868501 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression EXP Aripiprazole results in increased expression of RASD1 mRNA CTD PMID:17868501 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of RELB mRNA CTD PMID:31476115 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rig1 RNA sensor RIG-1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of RIGI mRNA CTD PMID:31476115 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 increases expression EXP Aripiprazole results in increased expression of SAE1 mRNA CTD PMID:17868501 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Sbno2 strawberry notch homolog 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SBNO2 mRNA CTD PMID:31476115 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527 		JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SERPINB2 mRNA CTD PMID:31476115 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of SH2B2 mRNA CTD PMID:31476115 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Slamf6 SLAM family member 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SLAMF6 mRNA CTD PMID:31476115 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects binding ISO Aripiprazole binds to SLC6A4 protein CTD PMID:21823597 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression EXP Aripiprazole results in decreased expression of SLCO2B1 mRNA CTD PMID:17868501 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Slit3 slit guidance ligand 3 increases expression EXP Aripiprazole results in increased expression of SLIT3 mRNA CTD PMID:17868501 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SMAD3 mRNA CTD PMID:31476115 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SOCS1 mRNA CTD PMID:31476115 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Syt17 synaptotagmin 17 decreases expression
multiple interactions		 ISO Aripiprazole results in decreased expression of SYT17 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of SYT17 mRNA		 CTD PMID:31476115 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TAB1 mRNA CTD PMID:31476115 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tacr3 tachykinin receptor 3 decreases expression
increases expression		 EXP Aripiprazole results in decreased expression of TACR3 mRNA
Aripiprazole results in increased expression of TACR3 mRNA		 CTD PMID:17868501 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Thbd thrombomodulin multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of THBD mRNA CTD PMID:31476115 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of THBS1 mRNA] CTD PMID:31476115 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TICAM1 mRNA CTD PMID:31476115 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TLR3 mRNA CTD PMID:31476115 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr5 toll-like receptor 5 increases expression
multiple interactions		 ISO Aripiprazole results in increased expression of TLR5 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of TLR5 mRNA		 CTD PMID:31476115 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of TNF mRNA] CTD PMID:31476115 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFAIP3 mRNA CTD PMID:31476115 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of TNFRSF11B mRNA] CTD PMID:31476115 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF12A mRNA CTD PMID:31476115 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TNFRSF14 mRNA CTD PMID:31476115 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF1B mRNA CTD PMID:31476115 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in decreased expression of TNFRSF10C mRNA] CTD PMID:31476115 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF8 mRNA CTD PMID:31476115 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF9 mRNA CTD PMID:31476115 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TNFSF10 mRNA CTD PMID:31476115 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf12 TNF superfamily member 12 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TNFSF12 mRNA CTD PMID:31476115 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tnfsf15 TNF superfamily member 15 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFSF15 mRNA CTD PMID:31476115 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tnfsf18 TNF superfamily member 18 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFSF18 mRNA CTD PMID:31476115 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Aripiprazole results in decreased expression of TUBB2A mRNA CTD PMID:17868501 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of VEGFA mRNA] CTD PMID:31476115 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP Aripiprazole results in increased expression of WEE1 mRNA CTD PMID:17868501 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
G Zfp354c zinc finger protein 354C increases expression EXP Aripiprazole results in increased expression of ZNF354C mRNA CTD PMID:17868501 NCBI chr10:35,129,720...35,145,717
Ensembl chr10:35,132,959...35,145,661 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        pharmacological role 19072
          neurotransmitter agent 16793
            serotonergic drug 4338
              serotonergic agonist 1021
                aripiprazole 167
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      carboacyl group 17694
                                        univalent carboacyl group 17694
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              lactam 8389
                                                delta-lactam 1207
                                                  aripiprazole 167
paths to the root