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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R,S)-Scoulerine
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Accession:CHEBI:31033 term browser browse the term
Definition:An alkaloid that has formula C19H21NO4.
Synonyms:related_synonym: Formula=C19H21NO4;   InChI=1S/C19H21NO4/c1-23-17-4-3-11-7-15-13-9-16(21)18(24-2)8-12(13)5-6-20(15)10-14(11)19(17)22/h3-4,8-9,15,21-22H,5-7,10H2,1-2H3;   InChIKey=KNWVMRVOBAFFMH-UHFFFAOYSA-N;   SMILES=COc1cc2CCN3Cc4c(CC3c2cc1O)ccc(OC)c4O;   Scoulerine
 xref: CAS:605-34-5;   CAS:6451-72-5;   KEGG:C12326;   LINCS:LSM-6499
 xref_mesh: MESH:C010941


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(R,S)-Scoulerine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO discretamine results in increased expression of BAX protein CTD PMID:32590070 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO discretamine results in decreased expression of BCL2 protein CTD PMID:32590070 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO 4-phenylbutyric acid inhibits the reaction [discretamine results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of DDIT3 protein] CTD PMID:32590070 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO discretamine results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO discretamine results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [discretamine results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of HSPA5 protein]		 CTD PMID:32590070 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      biological role 19835
        biochemical role 19552
          metabolite 19539
            alkaloid 8020
              (R,S)-Scoulerine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    main group molecular entity 19803
                      p-block molecular entity 19803
                        carbon group molecular entity 19744
                          organic molecular entity 19740
                            heteroorganic entity 19512
                              organonitrogen compound 18832
                                alkaloid 8020
                                  (R,S)-Scoulerine 5
paths to the root