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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-hydroxypyruvic acid
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Accession:CHEBI:30841 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.
Synonyms:related_synonym: 3-Hydroxy-2-oxopropanoic acid;   Formula=C3H4O4;   Hydroxypyruvic acid;   InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7);   InChIKey=HHDDCCUIIUWNGJ-UHFFFAOYSA-N;   SMILES=OCC(=O)C(O)=O
 alt_id: CHEBI:20083;   CHEBI:39999;   CHEBI:5813
 xref: Beilstein:1721079;   CAS:1113-60-6;   DrugBank:DB02951;   HMDB:HMDB0001352;   KEGG:C00168;   KNApSAcK:C00007563
 xref_mesh: MESH:C012375
 xref: PDBeChem:3PY;   PMID:13163046;   PMID:13328834;   PMID:13522577;   PMID:13522578;   PMID:13564115;   PMID:13798280;   PMID:20989501;   Reaxys:1721079;   Wikipedia:Hydroxypyruvic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:17180


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3-hydroxypyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        biochemical role 19569
          cofactor 16587
            pyruvic acid 53
              3-hydroxypyruvic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            heteroorganic entity 19549
                              organochalcogen compound 19309
                                organooxygen compound 19204
                                  carbon oxoacid 18689
                                    carboxylic acid 18686
                                      monocarboxylic acid 18026
                                        fatty acid 16849
                                          saturated fatty acid 16569
                                            propionic acid 3875
                                              pyruvic acid 53
                                                3-hydroxypyruvic acid 2
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