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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isophthalic acid
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Accession:CHEBI:30802 term browser browse the term
Definition:A benzenedicarboxylic acid that is benzene substituted by carboxy groups at position 1 and 3. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and terephthalic acids.
Synonyms:exact_synonym: benzene-1,3-dicarboxylic acid
 related_synonym: Formula=C8H6O4;   IPA;   InChI=1S/C8H6O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H,9,10)(H,11,12);   InChIKey=QQVIHTHCMHWDBS-UHFFFAOYSA-N;   SMILES=OC(=O)c1cccc(c1)C(O)=O;   m-benzenedicarboxylic acid;   meta-benzenedicarboxylic acid
 xref: CAS:121-91-5;   Gmelin:27618
 xref_mesh: MESH:C059768
 xref: MetaCyc:CPD0-1267;   PMID:24101250;   Reaxys:1909332;   Wikipedia:Isophthalic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30804


show annotations for term's descendants           Sort by:
isophthalic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gap43 growth associated protein 43 increases expression
multiple interactions 		ISO isophthalate analog results in increased expression of GAP43 mRNA; isophthalate analog results in increased expression of GAP43 protein
Go 6976 inhibits the reaction [isophthalate analog results in increased expression of GAP43 protein] 		CTD PMID:23643828 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions
affects localization 		ISO Go 6976 inhibits the reaction [isophthalate analog affects the localization of PRKCA protein] CTD PMID:23643828 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
chlorothalonil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of ACLY mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of ACLY mRNA 		CTD PMID:33246813 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of ACOT1 mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of ACOT1 mRNA 		CTD PMID:33246813 NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions
decreases expression 		ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of ACOX1 mRNA
tetrachloroisophthalonitrile results in decreased expression of ACOX1 mRNA 		CTD PMID:33246813 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of ACTA2 mRNA CTD PMID:32289622 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP tetrachloroisophthalonitrile binds to and results in increased activity of AHR protein CTD PMID:14636698 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Angpt4 angiopoietin 4 multiple interactions ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of ANGPT4 mRNA CTD PMID:33246813 NCBI chr 3:140,420,389...140,454,213
Ensembl chr 3:160,880,728...160,913,921 		JBrowse link
G Ano1 anoctamin 1 increases expression ISO tetrachloroisophthalonitrile results in increased expression of ANO1 mRNA CTD PMID:33246813 NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO tetrachloroisophthalonitrile results in increased expression of BAD mRNA CTD PMID:34549778 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO tetrachloroisophthalonitrile results in increased expression of BAX protein
tetrachloroisophthalonitrile results in increased expression of BAX mRNA 		CTD PMID:30586609 PMID:34549778 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of BCL2 protein CTD PMID:30586609 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bmp15 bone morphogenetic protein 15 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of BMP15 protein CTD PMID:30586609 NCBI chr  X:18,840,943...18,846,006
Ensembl chr  X:18,840,829...18,847,438 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression 		ISO tetrachloroisophthalonitrile results in increased activity of CASP3 protein
tetrachloroisophthalonitrile results in increased expression of CASP3 mRNA 		CTD PMID:34549778 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 increases expression ISO tetrachloroisophthalonitrile results in increased expression of CASP8 mRNA CTD PMID:34549778 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of CCL2 mRNA CTD PMID:32289622 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of CCL4 mRNA CTD PMID:32289622 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Cftr CF transmembrane conductance regulator decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of CFTR protein
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of CFTR protein; [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of CFTR mRNA 		CTD PMID:33246813 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Cldn1 claudin 1 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of CLDN1 mRNA; tetrachloroisophthalonitrile results in decreased expression of CLDN1 protein CTD PMID:34549778 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of COL1A1 mRNA; tetrachloroisophthalonitrile metabolite results in increased expression of COL1A1 protein CTD PMID:32289622 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of CPT1A mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of CPT1A mRNA 		CTD PMID:33246813 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of CXCL2 mRNA CTD PMID:32289622 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of CYP11A1 protein CTD PMID:30586609 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Defa5 defensin alpha 5 multiple interactions ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of DEFA5 mRNA CTD PMID:33246813 NCBI chr16:77,044,994...77,047,318
Ensembl chr16:77,044,994...77,047,318 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions
decreases expression 		ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of DGAT1 mRNA
tetrachloroisophthalonitrile results in decreased expression of DGAT1 mRNA 		CTD PMID:33246813 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of DGAT2 mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of DGAT2 mRNA 		CTD PMID:33246813 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO tetrachloroisophthalonitrile results in decreased activity of DIO1 protein CTD PMID:29228274 PMID:30561685 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO tetrachloroisophthalonitrile results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO tetrachloroisophthalonitrile results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985 		JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO tetrachloroisophthalonitrile results in decreased phosphorylation of EGFR protein CTD PMID:28426875 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases activity ISO tetrachloroisophthalonitrile results in increased activity of ERBB2 protein CTD PMID:11222871 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of FABP1 mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of FABP1 mRNA 		CTD PMID:33246813 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113 		JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of FASN mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of FASN mRNA 		CTD PMID:33246813 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of FSHR protein CTD PMID:30586609 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:10,952,329...11,160,288 		JBrowse link
G Gck glucokinase multiple interactions
decreases expression 		ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of GCK mRNA
tetrachloroisophthalonitrile results in decreased expression of GCK mRNA 		CTD PMID:33246813 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Gdf9 growth differentiation factor 9 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of GDF9 protein CTD PMID:30586609 NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of GJA1 protein CTD PMID:30586609 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions
decreases expression 		ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of GPAM mRNA
tetrachloroisophthalonitrile results in decreased expression of GPAM mRNA 		CTD PMID:33246813 NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of HSD17B4 protein CTD PMID:30586609 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:45,515,373...45,604,467 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of HSD3B1 protein CTD PMID:30586609 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Il1a interleukin 1 alpha increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of IL1A mRNA CTD PMID:32289622 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of IL1B mRNA CTD PMID:32289622 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of IL6 mRNA CTD PMID:32289622 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of INS1 protein
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of INS1 protein 		CTD PMID:33246813 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions
increases expression 		ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of KLF4 mRNA
tetrachloroisophthalonitrile results in increased expression of KLF4 mRNA 		CTD PMID:33246813 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO tetrachloroisophthalonitrile results in decreased phosphorylation of MAPK1 protein CTD PMID:28426875 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO tetrachloroisophthalonitrile results in decreased phosphorylation of MAPK3 protein CTD PMID:28426875 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO tetrachloroisophthalonitrile results in increased phosphorylation of MAPK8 protein CTD PMID:34549778 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mep1b meprin A subunit beta multiple interactions
increases expression 		ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of MEP1B mRNA
tetrachloroisophthalonitrile results in increased expression of MEP1B mRNA 		CTD PMID:33246813 NCBI chr18:12,641,041...12,667,759
Ensembl chr18:12,641,041...12,667,755 		JBrowse link
G Mif macrophage migration inhibitory factor decreases expression ISO tetrachloroisophthalonitrile metabolite results in decreased expression of MIF mRNA CTD PMID:32289622 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mlxip MLX interacting protein multiple interactions ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in increased expression of MLXIP mRNA CTD PMID:33246813 NCBI chr12:33,128,524...33,192,300
Ensembl chr12:38,789,404...38,853,059 		JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO tetrachloroisophthalonitrile metabolite results in decreased expression of MMP1 mRNA CTD PMID:32289622 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO tetrachloroisophthalonitrile metabolite results in decreased expression of MMP3 mRNA CTD PMID:32289622 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of MMP9 mRNA CTD PMID:32289622 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of MTTP mRNA CTD PMID:33246813 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650 		JBrowse link
G Muc1 mucin 1, cell surface associated increases expression ISO tetrachloroisophthalonitrile results in increased expression of MUC1 mRNA CTD PMID:33246813 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491 		JBrowse link
G Muc17 mucin 17, cell surface associated multiple interactions ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of MUC17 mRNA CTD PMID:33246813 NCBI chr12:25,139,076...25,175,249 JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming increases expression
decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in increased expression of MUC2 mRNA
tetrachloroisophthalonitrile results in decreased expression of MUC2 protein
[tetrachloroisophthalonitrile co-treated with procymidone] results in decreased expression of MUC2 protein 		CTD PMID:33246813 NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO tetrachloroisophthalonitrile results in increased activity of NR1I2 protein CTD PMID:20143881 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Ocln occludin decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of OCLN mRNA CTD PMID:34549778 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of PKLR mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of PKLR mRNA 		CTD PMID:33246813 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pla2g4a phospholipase A2 group 4A multiple interactions ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of PLA2G4A mRNA CTD PMID:33246813 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of PPARA mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of PPARA mRNA 		CTD PMID:33246813 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of PPARG mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of PPARG mRNA 		CTD PMID:33246813 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of PTGS2 mRNA CTD PMID:32289622 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rad51 RAD51 recombinase increases expression ISO tetrachloroisophthalonitrile results in increased expression of RAD51 protein CTD PMID:30586609 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of S100A8 mRNA CTD PMID:32289622 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO tetrachloroisophthalonitrile metabolite results in decreased expression of S100A9 mRNA CTD PMID:32289622 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
decreases expression 		ISO [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of SCD1 mRNA
tetrachloroisophthalonitrile results in decreased expression of SCD1 mRNA 		CTD PMID:33246813 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of SLC12A2 mRNA CTD PMID:33246813 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 multiple interactions
increases expression 		ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of SLC26A3 mRNA
tetrachloroisophthalonitrile results in increased expression of SLC26A3 mRNA 		CTD PMID:33246813 NCBI chr 6:53,751,415...53,792,300
Ensembl chr 6:53,751,415...53,792,294 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 increases expression ISO tetrachloroisophthalonitrile results in increased expression of SLC26A6 mRNA CTD PMID:33246813 NCBI chr 8:118,438,110...118,448,271
Ensembl chr 8:118,438,180...118,448,270 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression
multiple interactions 		ISO tetrachloroisophthalonitrile results in decreased expression of SLC27A2 mRNA
[procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of SLC27A2 mRNA 		CTD PMID:33246813 NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581 		JBrowse link
G Slc9a3 solute carrier family 9 member A3 multiple interactions
increases expression 		ISO [tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of SLC9A3 mRNA
tetrachloroisophthalonitrile results in increased expression of SLC9A3 mRNA 		CTD PMID:33246813 NCBI chr 1:30,953,215...30,996,209
Ensembl chr 1:30,953,216...30,996,002 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO tetrachloroisophthalonitrile results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO tetrachloroisophthalonitrile results in decreased expression of TJP1 mRNA CTD PMID:34549778 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of TLR4 mRNA CTD PMID:32289622 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO tetrachloroisophthalonitrile metabolite results in increased expression of TNF mRNA CTD PMID:32289622 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
Di-n-hexyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO di-n-hexyl phthalate results in decreased expression of ACADL mRNA CTD PMID:33043605 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:75,783,689...75,822,164 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO di-n-hexyl phthalate results in decreased expression of ACADM mRNA CTD PMID:33043605 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO di-n-hexyl phthalate results in decreased expression of ACSL1 mRNA CTD PMID:33043605 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression EXP di-n-hexyl phthalate results in decreased expression of ALDH2 mRNA CTD PMID:33983380 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Ar androgen receptor multiple interactions ISO di-n-hexyl phthalate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; di-n-hexyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:15840436 PMID:28571686 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO di-n-hexyl phthalate results in increased expression of BAX mRNA CTD PMID:33043605 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO di-n-hexyl phthalate results in decreased expression of BCL2 mRNA CTD PMID:33043605 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Casp3 caspase 3 increases expression ISO di-n-hexyl phthalate results in increased expression of CASP3 mRNA CTD PMID:33043605 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 increases expression ISO di-n-hexyl phthalate results in increased expression of CASP8 mRNA CTD PMID:33043605 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Cela3b chymotrypsin like elastase 3B increases expression EXP di-n-hexyl phthalate results in increased expression of ELA3B mRNA CTD PMID:33983380 NCBI chr 5:149,628,773...149,636,937
Ensembl chr 5:154,912,170...154,920,333 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO di-n-hexyl phthalate results in decreased expression of CPT1B mRNA CTD PMID:33043605 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of CYP11A1 mRNA; di-n-hexyl phthalate results in decreased expression of CYP11A1 protein CTD PMID:22112501 PMID:23754470 PMID:26934186 PMID:33983380 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases expression EXP di-n-hexyl phthalate results in decreased expression of CYP11B1 mRNA CTD PMID:22112501 PMID:33983380 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression EXP di-n-hexyl phthalate results in decreased expression of CYP11B2 mRNA CTD PMID:33983380 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of CYP17A1 mRNA; di-n-hexyl phthalate results in decreased expression of CYP17A1 protein CTD PMID:22112501 PMID:23754470 PMID:26934186 PMID:33983380 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of CYP46A1 mRNA CTD PMID:33983380 NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression EXP di-n-hexyl phthalate results in decreased expression of CYP51 mRNA CTD PMID:33983380 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP di-n-hexyl phthalate results in decreased expression of DHCR7 mRNA CTD PMID:33983380 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Dhh desert hedgehog signaling molecule increases expression EXP di-n-hexyl phthalate results in increased expression of DHH mRNA; di-n-hexyl phthalate results in increased expression of DHH protein CTD PMID:32693021 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:131,929,857...131,935,352 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression EXP di-n-hexyl phthalate results in decreased expression of EBP mRNA CTD PMID:33983380 NCBI chr  X:16,971,372...16,977,782
Ensembl chr  X:16,971,405...16,977,781 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO di-n-hexyl phthalate results in decreased expression of ELOVL5 mRNA CTD PMID:33043605 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
increases expression
multiple interactions 		ISO
EXP 		di-n-hexyl phthalate analog binds to ESR1 protein
di-n-hexyl phthalate results in increased expression of ESR1 mRNA
di-n-hexyl phthalate binds to and results in increased activity of ESR1 protein; di-n-hexyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Tamoxifen inhibits the reaction [di-n-hexyl phthalate binds to and results in increased activity of ESR1 protein] 		CTD PMID:15464722 PMID:15840436 PMID:22112501 PMID:28571686 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding 		ISO di-n-hexyl phthalate binds to and results in decreased activity of ESR2 protein; di-n-hexyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]
di-n-hexyl phthalate analog binds to ESR2 protein 		CTD PMID:15464722 PMID:15840436 PMID:28571686 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO di-n-hexyl phthalate results in decreased expression of FADS2 mRNA CTD PMID:33043605 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO di-n-hexyl phthalate results in decreased expression of FASN mRNA CTD PMID:33043605 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression EXP di-n-hexyl phthalate results in decreased expression of FDPS mRNA CTD PMID:33983380 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation EXP di-n-hexyl phthalate results in increased phosphorylation of GSK3B protein CTD PMID:32693021 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP di-n-hexyl phthalate results in decreased expression of HMGCR mRNA CTD PMID:26934186 PMID:33983380 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of HMGCS1 mRNA CTD PMID:26934186 PMID:33983380 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of HSD11B1 protein CTD PMID:32693021 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 increases expression EXP di-n-hexyl phthalate results in increased expression of HSD17B3 mRNA CTD PMID:26934186 NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of HSD3B1 mRNA; di-n-hexyl phthalate results in decreased expression of HSD3B1 protein CTD PMID:26934186 PMID:32693021 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 decreases expression EXP di-n-hexyl phthalate results in decreased expression of HSD3B3 mRNA; di-n-hexyl phthalate results in decreased expression of HSD3B3 protein CTD PMID:32693021 PMID:33983380 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:188,826,110...188,904,981 		JBrowse link
G Idi2l3 isopentenyl-diphosphate delta isomerase 2 like 3 decreases expression EXP di-n-hexyl phthalate results in decreased expression of IDI2L3 mRNA CTD PMID:33983380 NCBI chr17:61,518,138...61,535,484 JBrowse link
G Il1b interleukin 1 beta increases expression ISO di-n-hexyl phthalate results in increased expression of IL1B mRNA CTD PMID:33043605 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP di-n-hexyl phthalate results in decreased expression of INHA mRNA CTD PMID:22112501 PMID:33983380 NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:33983380 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insl3 insulin-like 3 decreases expression EXP di-n-hexyl phthalate results in decreased expression of INSL3 mRNA CTD PMID:22112501 PMID:33983380 NCBI chr16:18,432,668...18,434,539 JBrowse link
G Ldlr low density lipoprotein receptor decreases expression EXP di-n-hexyl phthalate results in decreased expression of LDLR mRNA CTD PMID:33983380 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP di-n-hexyl phthalate results in increased expression of LHB protein CTD PMID:32693021 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP di-n-hexyl phthalate results in decreased expression of LHCGR mRNA; di-n-hexyl phthalate results in decreased expression of LHCGR protein CTD PMID:32693021 PMID:33983380 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP di-n-hexyl phthalate results in increased phosphorylation of MAPK1 protein CTD PMID:32693021 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP di-n-hexyl phthalate results in increased phosphorylation of MAPK3 protein CTD PMID:32693021 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression EXP di-n-hexyl phthalate results in decreased expression of MVD mRNA CTD PMID:33983380 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of NR0B1 mRNA CTD PMID:33983380 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects binding
increases activity 		ISO di-n-hexyl phthalate binds to NR1I3 protein
di-n-hexyl phthalate results in increased activity of NR1I3 protein 		CTD PMID:25938866 PMID:28927721 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL decreases expression EXP di-n-hexyl phthalate results in decreased expression of NSDHL mRNA CTD PMID:33983380 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO di-n-hexyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO di-n-hexyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO di-n-hexyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression EXP di-n-hexyl phthalate results in decreased expression of PPARGC1A protein CTD PMID:32693021 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO di-n-hexyl phthalate binds to RXRA protein CTD PMID:23843199 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO di-n-hexyl phthalate binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,818,707...4,824,968
Ensembl chr20:4,818,709...4,825,359 		JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO di-n-hexyl phthalate binds to RXRG protein CTD PMID:23843199 NCBI chr13:82,276,330...82,318,097
Ensembl chr13:82,276,291...82,318,095 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of SCARB1 mRNA CTD PMID:22112501 PMID:23754470 PMID:26934186 PMID:33983380 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Shox1 SHOX homeobox 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of RHOX10 mRNA CTD PMID:22112501 NCBI chr  X:121,553,770...121,560,788 JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of SIRT1 protein CTD PMID:32693021 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP di-n-hexyl phthalate results in decreased expression of STAR mRNA CTD PMID:22112501 PMID:23754470 PMID:26934186 PMID:33983380 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP di-n-hexyl phthalate results in decreased expression of TGFB1 mRNA CTD PMID:22112501 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression EXP di-n-hexyl phthalate results in decreased expression of TM7SF2 mRNA CTD PMID:33983380 NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO di-n-hexyl phthalate results in increased expression of TNF mRNA CTD PMID:33043605 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Wnt7a Wnt family member 7A decreases expression EXP di-n-hexyl phthalate results in decreased expression of WNT7A mRNA CTD PMID:22112501 PMID:33983380 NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149 		JBrowse link
iopromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression EXP iopromide results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO iopromide results in increased secretion of HEXB protein CTD PMID:34774977 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO iopromide results in decreased phosphorylation of MAPK1 protein CTD PMID:34774977 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO iopromide results in decreased phosphorylation of MAPK3 protein CTD PMID:34774977 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO iopromide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP iopromide results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G RT1-Da RT1 class II, locus Da affects expression ISO iopromide affects the expression of HLA-DRA mRNA CTD PMID:25811541 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      group 20803
        inorganic group 20299
          oxo group 19440
            organic oxo compound 19440
              carbonyl compound 19440
                dicarboxylic acids and O-substituted derivatives 12725
                  dicarboxylic acid 12722
                    benzenedicarboxylic acid 10960
                      isophthalic acid 131
                        2-hydroxyisophthalic acid + 62
                        isophthalamide + 7
                        isophthalonitrile + 76
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      aromatic carboxylic acid 14051
                                        benzoic acids 14017
                                          benzenedicarboxylic acid 10960
                                            isophthalic acid 131
                                              2-hydroxyisophthalic acid + 62
                                              isophthalamide + 7
                                              isophthalonitrile + 76
paths to the root