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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tin(2+)
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Accession:CHEBI:30475 term browser browse the term
Definition:A divalent metal cation that has formula Sn.
Synonyms:exact_synonym: tin(2+) ion;   tin(II) cation
 related_synonym: Formula=Sn;   InChI=1S/Sn/q+2;   InChIKey=IUTCEZPPWBHGIX-UHFFFAOYSA-N;   SMILES=[Sn++];   Sn(2+);   Tin, ion (Sn2+)
 xref: CAS:22541-90-8;   Gmelin:6867


show annotations for term's descendants           Sort by:
tin(II) chloride (anhydrous) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein CTD PMID:16959961 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein CTD PMID:16959961 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO stannous chloride results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
affects response to substance
increases activity		 ISO stannous chloride inhibits the reaction [Estradiol binds to ESR1 protein]
stannous chloride results in decreased expression of ESR1 mRNA; stannous chloride results in decreased expression of ESR1 protein
ESR1 protein affects the susceptibility to stannous chloride
stannous chloride results in increased activity of ESR1 protein		 CTD PMID:12746304 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO stannous chloride results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO stannous chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases activity		 EXP [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Heme; [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Superoxides; [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein; [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein CTD PMID:16959961 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Orm1 orosomucoid 1 increases expression ISO stannous chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked increases expression ISO stannous chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:37,607,553...37,856,183
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO stannous chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO stannous chloride results in increased expression of SLC2A1 mRNA CTD PMID:19000923 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Tfrc transferrin receptor increases expression ISO stannous chloride results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [stannous chloride results in increased abundance of Tin] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO stannous chloride results in increased expression of VEGFA mRNA CTD PMID:19000923 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      molecular entity 19878
        ion 17081
          monoatomic ion 16385
            monoatomic cation 15609
              monoatomic dication 9944
                tin(2+) 14
                  tin(II) chloride (anhydrous) + 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        tin atom 1257
                          tin molecular entity 1257
                            elemental tin 17
                              tin cation 14
                                tin(2+) 14
                                  tin(II) chloride (anhydrous) + 14
paths to the root