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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tin(2+)
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Accession:CHEBI:30475 term browser browse the term
Definition:A divalent metal cation that has formula Sn.
Synonyms:exact_synonym: tin(2+) ion;   tin(II) cation
 related_synonym: Formula=Sn;   InChI=1S/Sn/q+2;   InChIKey=IUTCEZPPWBHGIX-UHFFFAOYSA-N;   SMILES=[Sn++];   Sn(2+);   Tin, ion (Sn2+)
 xref: CAS:22541-90-8;   Gmelin:6867


show annotations for term's descendants           Sort by:
tin(II) chloride (anhydrous) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein CTD PMID:16959961 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions ISO [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein CTD PMID:16959961 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases expression EXP stannous chloride results in increased expression of CYP2A5 protein CTD PMID:9698299 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Dmp1 dentin matrix protein 1 increases expression EXP stannous chloride results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
decreases expression
affects response to substance
increases activity		 ISO stannous chloride inhibits the reaction [Estradiol binds to ESR1 protein]
stannous chloride results in decreased expression of ESR1 mRNA; stannous chloride results in decreased expression of ESR1 protein
ESR1 protein affects the susceptibility to stannous chloride
stannous chloride results in increased activity of ESR1 protein		 CTD PMID:12746304 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G F3 coagulation factor III increases expression ISO stannous chloride results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Fosl1 fos-like antigen 1 increases expression EXP stannous chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases activity		 ISO [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Heme; [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Superoxides; [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein; [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein CTD PMID:16959961 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Orm1 orosomucoid 1 increases expression EXP stannous chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400 		JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression EXP stannous chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:155,945,071...156,198,282
Ensembl chr  X:155,945,071...156,198,308 		JBrowse link
G Prl2c3 prolactin family 2, subfamily c, member 3 increases expression EXP stannous chloride results in increased expression of PRL2C3 mRNA CTD PMID:19000923 NCBI chr13:12,805,705...12,814,982
Ensembl chr13:12,805,705...12,814,968 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP stannous chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 increases expression EXP stannous chloride results in increased expression of SLC2A1 mRNA CTD PMID:19000923 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Tfrc transferrin receptor increases expression EXP stannous chloride results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [stannous chloride results in increased abundance of Tin] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP stannous chloride results in increased expression of VEGFA mRNA CTD PMID:19000923 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22276
    chemical entity 22275
      molecular entity 22271
        ion 18075
          monoatomic ion 17302
            monoatomic cation 16441
              monoatomic dication 10083
                tin(2+) 16
                  tin(II) chloride (anhydrous) + 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 22276
    subatomic particle 22271
      composite particle 22271
        hadron 22271
          baryon 22271
            nucleon 22271
              atomic nucleus 22271
                atom 22271
                  main group element atom 22150
                    p-block element atom 22150
                      carbon group element atom 21953
                        tin atom 1238
                          tin molecular entity 1238
                            elemental tin 19
                              tin cation 16
                                tin(2+) 16
                                  tin(II) chloride (anhydrous) + 16
paths to the root