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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tin(2+)
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Accession:CHEBI:30475 term browser browse the term
Definition:A divalent metal cation that has formula Sn.
Synonyms:exact_synonym: tin(2+) ion;   tin(II) cation
 related_synonym: Formula=Sn;   InChI=1S/Sn/q+2;   InChIKey=IUTCEZPPWBHGIX-UHFFFAOYSA-N;   SMILES=[Sn++];   Sn(2+);   Tin, ion (Sn2+)
 xref: CAS:22541-90-8;   Gmelin:6867


show annotations for term's descendants           Sort by:
tin(II) chloride (anhydrous) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator multiple interactions ISO [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein CTD PMID:16959961 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein CTD PMID:16959961 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 increases expression ISO stannous chloride results in increased expression of CYP2A5 protein CTD PMID:9698299 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G DMP1 dentin matrix acidic phosphoprotein 1 increases expression ISO stannous chloride results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr 4:87,650,280...87,664,357
Ensembl chr 4:87,650,280...87,664,361 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases activity
affects response to substance
decreases expression		 EXP stannous chloride inhibits the reaction [Estradiol binds to ESR1 protein]
stannous chloride results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to stannous chloride
stannous chloride results in decreased expression of ESR1 mRNA; stannous chloride results in decreased expression of ESR1 protein		 CTD PMID:12746304 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP stannous chloride results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression ISO stannous chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases activity		 ISO [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Heme; [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Superoxides; [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein; [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein CTD PMID:16959961 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G ORM1 orosomucoid 1 increases expression ISO stannous chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked increases expression ISO stannous chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713 		JBrowse link
G SCARB1 scavenger receptor class B member 1 increases expression ISO stannous chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression ISO stannous chloride results in increased expression of SLC2A1 mRNA CTD PMID:19000923 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G TFRC transferrin receptor increases expression ISO stannous chloride results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [stannous chloride results in increased abundance of Tin] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342 		JBrowse link
G VEGFA vascular endothelial growth factor A increases expression ISO stannous chloride results in increased expression of VEGFA mRNA CTD PMID:19000923 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26495
    chemical entity 26475
      molecular entity 26457
        ion 19889
          monoatomic ion 18859
            monoatomic cation 18224
              monoatomic dication 10462
                tin(2+) 15
                  tin(II) chloride (anhydrous) + 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 26495
    subatomic particle 26471
      composite particle 26471
        hadron 26471
          baryon 26471
            nucleon 26471
              atomic nucleus 26471
                atom 26471
                  main group element atom 26207
                    p-block element atom 26207
                      carbon group element atom 25650
                        tin atom 1232
                          tin molecular entity 1232
                            elemental tin 18
                              tin cation 15
                                tin(2+) 15
                                  tin(II) chloride (anhydrous) + 15
paths to the root