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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzalkonium chloride
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Accession:CHEBI:3020 term browser browse the term
Definition:A class of quaternary ammonium chloride salts in which the nitrogen is substituted by a benzyl group, two methyl groups and an even-numbered alkyl chain.
Synonyms:related_synonym: ADBAC;   Alkyl dimethylbenzyl ammonium chloride;   Alkylbenzyldimethylammonium chloride;   Alkyldimethyl(phenylmethyl)quaternary ammonium chlorides;   Alkyldimethylbenzylammonium chloride;   benzalkonii chloridum;   benzalkonium chlorides;   chlorure de benzalkonium;   cloruro de benzalconio
 alt_id: MESH:D001548
 xref: CAS:8001-54-5
 xref_mesh: MESH:D001548
 xref: kegg.compound:C08037;   kegg.drug:D00857;   pubmed:17660979;   pubmed:22692451;   pubmed:23078159;   pubmed:23102555;   pubmed:23278376;   pubmed:23439005;   pubmed:23519403;   pubmed:23542350;   pubmed:23651563;   pubmed:23682619;   pubmed:23726247;   pubmed:23792171;   pubmed:23861389;   pubmed:23892748;   pubmed:23893017;   pubmed:23987445;   pubmed:23987991;   pubmed:23991114;   pubmed:7526642
 chemrof_smiles: *[N+](C)(C)Cc1ccccc1.[Cl-]
 chemrof_formula: C9H13ClNR


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benzalkonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression ISO Benzalkonium Compounds results in increased expression of AACS mRNA CTD PMID:31199489 NCBI chr12:36,774,471...36,817,835
Ensembl chr12:36,774,471...36,822,543 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA1 mRNA CTD PMID:26919959 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO Benzalkonium Compounds results in increased expression of ABCA12 mRNA CTD PMID:25377654 NCBI chr 9:80,272,121...80,445,340
Ensembl chr 9:80,272,127...80,445,340 		JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA6 mRNA CTD PMID:20713136 NCBI chr10:95,642,026...95,711,535
Ensembl chr10:95,641,900...95,710,899 		JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ACOD1 mRNA CTD PMID:30171875 NCBI chr15:86,286,531...86,295,803
Ensembl chr15:86,286,579...86,295,687 		JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic increases expression ISO Benzalkonium Compounds results in increased expression of ACP6 mRNA CTD PMID:31199489 NCBI chr 2:187,400,786...187,421,877
Ensembl chr 2:187,349,186...187,422,743 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression ISO Benzalkonium Compounds results in increased expression of ACSL4 mRNA CTD PMID:31199489 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:110,739,648...110,803,261 		JBrowse link
G Ada adenosine deaminase increases expression ISO Benzalkonium Compounds results in increased expression of ADA mRNA CTD PMID:30171875 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Benzalkonium Compounds results in decreased expression of ADH1 mRNA CTD PMID:31199489 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291 		JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO Benzalkonium Compounds results in decreased expression of ADORA1 mRNA CTD PMID:30171875 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA CTD PMID:30171875 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA CTD PMID:30171875 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:116,913,656...116,918,745 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Benzalkonium Compounds results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Alb albumin decreases expression ISO Benzalkonium Compounds results in decreased expression of ALB mRNA CTD PMID:31199489 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 increases expression ISO Benzalkonium Compounds results in increased expression of AMIGO2 mRNA CTD PMID:37149095 NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218 		JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA1 mRNA CTD PMID:31199489 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA2 mRNA CTD PMID:31199489 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOC1 mRNA CTD PMID:31199489 NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:88,474,663...88,478,155 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Benzalkonium Compounds results in increased expression of AQP3 mRNA CTD PMID:30171875 NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685 		JBrowse link
G Areg amphiregulin increases expression ISO Benzalkonium Compounds results in increased expression of AREG mRNA CTD PMID:30171875 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Arg2 arginase 2 increases expression ISO Benzalkonium Compounds results in increased expression of ARG2 mRNA CTD PMID:30171875 NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375 		JBrowse link
G Art3 ADP-ribosyltransferase 3 decreases expression ISO Benzalkonium Compounds results in decreased expression of ART3 mRNA CTD PMID:31199489 NCBI chr14:15,921,540...16,003,764
Ensembl chr14:15,921,395...15,949,806 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5F1E mRNA CTD PMID:31199489 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214 		JBrowse link
G Atp5mg ATP synthase membrane subunit G decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5MG mRNA CTD PMID:31199489 NCBI chr 8:54,122,457...54,130,407
Ensembl chr 8:54,122,457...54,132,831 		JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 affects response to substance ISO B3GALT4 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,937,974...4,939,549
Ensembl chr20:4,937,674...4,939,885 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO Benzalkonium Compounds results in increased expression of BAMBI mRNA CTD PMID:20146380 NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Benzalkonium Compounds results in increased expression of BCL3 mRNA CTD PMID:30171875 NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368 		JBrowse link
G Btc betacellulin decreases expression ISO Benzalkonium Compounds results in decreased expression of BTC mRNA CTD PMID:30171875 NCBI chr14:16,992,668...17,031,178
Ensembl chr14:16,992,193...17,033,078 		JBrowse link
G C3 complement C3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA CTD PMID:30171875 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions 		ISO Benzalkonium Compounds analog results in increased cleavage of CASP3 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of CASP3 protein] 		CTD PMID:31982400 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO Benzalkonium Compounds results in increased expression of CCL11 protein CTD PMID:30517752 NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion 		ISO Benzalkonium Compounds results in increased expression of CCL2 mRNA; Benzalkonium Compounds results in increased expression of CCL2 protein
Benzalkonium Compounds results in increased secretion of CCL2 protein 		CTD PMID:30171875 PMID:30517752 PMID:31707104 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Benzalkonium Compounds results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCL24 mRNA CTD PMID:30171875 NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions 		ISO Benzalkonium Compounds results in increased expression of CCL3 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein 		CTD PMID:30517752 PMID:31158415 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
increases expression
multiple interactions 		ISO Benzalkonium Compounds results in decreased expression of CCL4 mRNA; Benzalkonium Compounds results in decreased expression of CCL4 protein
Benzalkonium Compounds results in increased expression of CCL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein 		CTD PMID:18353026 PMID:20713136 PMID:30517752 PMID:31158415 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCL5 protein CTD PMID:30517752 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Benzalkonium Compounds results in increased expression of CCL7 mRNA; Benzalkonium Compounds results in increased expression of CCL7 protein CTD PMID:30171875 PMID:30517752 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CCN3 mRNA CTD PMID:30171875 NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCR4 mRNA CTD PMID:30171875 NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCR5 mRNA CTD PMID:30171875 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd177 CD177 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA CTD PMID:30171875 NCBI chr 1:89,467,926...89,488,490
Ensembl chr 1:89,467,926...89,488,443 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA CTD PMID:30171875 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951 		JBrowse link
G Cd300c2 CD300C molecule 2 increases expression ISO Benzalkonium Compounds results in increased expression of CD300C2 mRNA CTD PMID:30171875 NCBI chr10:100,752,301...100,757,549
Ensembl chr10:100,752,621...100,757,332 		JBrowse link
G Cdc6 cell division cycle 6 multiple interactions
decreases expression 		ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Benzalkonium Compounds results in decreased expression of CDC6 protein]
Benzalkonium Compounds results in decreased expression of CDC6 mRNA; Benzalkonium Compounds results in decreased expression of CDC6 protein 		CTD PMID:36725023 NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241 		JBrowse link
G Cfap61 cilia and flagella associated protein 61 increases expression ISO Benzalkonium Compounds results in increased expression of CFAP61 mRNA CTD PMID:31199489 NCBI chr 3:153,807,672...154,086,591
Ensembl chr 3:153,807,735...154,086,590 		JBrowse link
G Cfd complement factor D decreases expression ISO Benzalkonium Compounds results in decreased expression of CFD mRNA CTD PMID:30171875 NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Benzalkonium Compounds results in increased expression of CHI3L1 mRNA CTD PMID:30171875 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Benzalkonium Compounds results in decreased expression of CHRNB4 mRNA CTD PMID:30171875 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:64,313,669...64,333,248 		JBrowse link
G Cimap1d CIMAP1 family member D decreases expression ISO Benzalkonium Compounds results in decreased expression of CIMAP1D mRNA CTD PMID:30171875 NCBI chr 7:10,700,067...10,715,742
Ensembl chr 7:10,700,510...10,715,738 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CLCF1 mRNA CTD PMID:30171875 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Cnfn cornifelin increases expression ISO Benzalkonium Compounds results in increased expression of CNFN mRNA; Benzalkonium Compounds results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr 1:90,079,409...90,081,556
Ensembl chr 1:90,078,552...90,081,556 		JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CSF1 protein CTD PMID:30517752 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of CSF2 protein CTD PMID:30517752 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CSF3 protein CTD PMID:30517752 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS1 mRNA CTD PMID:30171875 NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions 		ISO Benzalkonium Compounds results in increased expression of CXCL10 mRNA; Benzalkonium Compounds results in increased expression of CXCL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein 		CTD PMID:23445166 PMID:30517752 PMID:31158415 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions 		ISO Benzalkonium Compounds results in increased expression of CXCL2 mRNA; Benzalkonium Compounds results in increased expression of CXCL2 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein 		CTD PMID:30171875 PMID:30517752 PMID:31158415 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression 		ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA
Benzalkonium Compounds results in increased expression of CXCL1 protein; Benzalkonium Compounds results in increased expression of CXCL3 mRNA 		CTD PMID:30171875 PMID:30517752 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR1 mRNA CTD PMID:30806763 NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression 		ISO Benzalkonium Compounds results in decreased expression of CYP1A1 mRNA
Benzalkonium Compounds results in increased expression of CYP1A1 mRNA 		CTD PMID:20713136 PMID:30806763 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO Benzalkonium Compounds results in increased expression of CYP51 mRNA CTD PMID:31199489 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Benzalkonium Compounds results in increased expression of DDIT3 mRNA CTD PMID:37149095 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benzalkonium Compounds results in increased expression of DHCR24 mRNA CTD PMID:31199489 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases activity
increases expression 		ISO Benzalkonium Compounds results in decreased activity of DHCR7 protein
Benzalkonium Compounds results in increased expression of DHCR7 mRNA 		CTD PMID:26919959 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of DLK1 mRNA CTD PMID:31199489 NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Benzalkonium Compounds results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Benzalkonium Compounds results in increased expression of DUSP10 mRNA CTD PMID:37149095 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression ISO Benzalkonium Compounds results in increased expression of EBP mRNA CTD PMID:26919959 NCBI chr  X:16,971,372...16,977,782
Ensembl chr  X:16,971,405...16,977,781 		JBrowse link
G Egf epidermal growth factor decreases expression ISO Benzalkonium Compounds results in decreased expression of EGF mRNA CTD PMID:30171875 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Benzalkonium Compounds results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation 		ISO [Benzalkonium Compounds co-treated with G3BP1 protein] results in increased phosphorylation of EIF2AK3 protein
Benzalkonium Compounds results in increased phosphorylation of EIF2AK3 protein 		CTD PMID:38734221 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions 		ISO Benzalkonium Compounds results in increased phosphorylation of EIF2S1 protein
[Benzalkonium Compounds co-treated with G3BP1 protein] results in increased phosphorylation of EIF2S1 protein 		CTD PMID:38734221 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of ELF3 mRNA CTD PMID:30171875 NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL1 mRNA CTD PMID:29155129 NCBI chr 5:137,246,781...137,251,351
Ensembl chr 5:137,246,849...137,251,352 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL6 mRNA CTD PMID:31199489 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549 		JBrowse link
G Endou endonuclease, poly(U)-specific increases expression ISO Benzalkonium Compounds results in increased expression of ENDOU mRNA CTD PMID:30171875 NCBI chr 7:130,723,972...130,745,672
Ensembl chr 7:130,723,972...130,745,672 		JBrowse link
G Eno1 enolase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ENO1 mRNA CTD PMID:31199489 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003 		JBrowse link
G Etnk1 ethanolamine kinase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ETNK1 mRNA CTD PMID:31199489 NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721 		JBrowse link
G Exo1 exonuclease 1 increases expression ISO Benzalkonium Compounds results in increased expression of EXO1 mRNA CTD PMID:30171875 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861 		JBrowse link
G Ezr ezrin increases expression ISO Benzalkonium Compounds results in increased expression of EZR mRNA; Benzalkonium Compounds results in increased expression of EZR protein CTD PMID:29893927 NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573 		JBrowse link
G Fam83a family with sequence similarity 83, member A increases expression ISO Benzalkonium Compounds results in increased expression of FAM83A mRNA CTD PMID:30171875 NCBI chr 7:91,412,366...91,436,819
Ensembl chr 7:91,412,366...91,436,910 		JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression ISO Benzalkonium Compounds results in increased expression of FGR mRNA CTD PMID:30171875 NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:150,473,792...150,503,169 		JBrowse link
G Flg filaggrin increases expression ISO Benzalkonium Compounds results in increased expression of FLG mRNA CTD PMID:30171875 NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968 		JBrowse link
G Foxc1 forkhead box C1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA CTD PMID:30171875 NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347 		JBrowse link
G Foxn1 forkhead box N1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA CTD PMID:30171875 NCBI chr10:63,749,461...63,778,468
Ensembl chr10:63,749,461...63,771,771 		JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA CTD PMID:30171875 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 multiple interactions ISO [Benzalkonium Compounds co-treated with G3BP1 protein] results in increased phosphorylation of EIF2AK3 protein; [Benzalkonium Compounds co-treated with G3BP1 protein] results in increased phosphorylation of EIF2S1 protein CTD PMID:38734221 NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA CTD PMID:30171875 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLC mRNA CTD PMID:30806763 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Benzalkonium Compounds results in increased expression of GPX2 mRNA CTD PMID:30171875 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Benzalkonium Compounds results in increased expression of HBEGF mRNA CTD PMID:30171875 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA CTD PMID:30171875 NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Benzalkonium Compounds results in increased expression of HERPUD1 mRNA CTD PMID:37149095 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA CTD PMID:30171875 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of HIF1A mRNA CTD PMID:30171875 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Benzalkonium Compounds results in increased expression of HMGCR mRNA CTD PMID:26919959 PMID:31199489 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of HMGCS2 mRNA CTD PMID:31199489 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Benzalkonium Compounds results in increased expression of HMOX1 mRNA CTD PMID:37149095 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hoxa7 homeobox A7 decreases expression ISO Benzalkonium Compounds results in decreased expression of HOXA7 mRNA CTD PMID:30171875 NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:82,646,364...82,648,241 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO Benzalkonium Compounds results in increased expression of HSD17B7 mRNA CTD PMID:31199489 NCBI chr13:84,702,875...84,722,810
Ensembl chr13:84,705,631...84,722,754 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Benzalkonium Compounds results in decreased expression of HSPA5 mRNA CTD PMID:28236482 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Benzalkonium Compounds results in increased expression of ICAM1 mRNA; Benzalkonium Compounds results in increased expression of ICAM1 protein CTD PMID:21742781 PMID:30806763 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO Benzalkonium Compounds results in increased expression of ID1 mRNA CTD PMID:37149095 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Benzalkonium Compounds results in increased expression of IDI1 mRNA CTD PMID:31199489 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Ifng interferon gamma increases expression ISO Benzalkonium Compounds results in increased expression of IFNG protein CTD PMID:30517752 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression 		ISO Benzalkonium Compounds results in increased expression of and results in decreased secretion of IL10 protein
Benzalkonium Compounds results in increased expression of IL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein 		CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of IL13RA2 mRNA CTD PMID:30171875 NCBI chr  X:115,814,620...115,886,080
Ensembl chr  X:115,814,622...115,841,455 		JBrowse link
G Il15 interleukin 15 increases expression ISO Benzalkonium Compounds results in increased expression of IL15 protein CTD PMID:30517752 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il17f interleukin 17F increases expression ISO Benzalkonium Compounds results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:30,686,532...30,697,918
Ensembl chr 9:30,686,538...30,697,918 		JBrowse link
G Il18 interleukin 18 increases expression ISO Benzalkonium Compounds results in increased expression of IL18 protein
Benzalkonium Compounds results in increased expression of IL18 mRNA 		CTD PMID:30517752 PMID:30806763 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1a interleukin 1 alpha increases secretion
increases expression
multiple interactions 		ISO Benzalkonium Compounds results in increased secretion of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A mRNA; Benzalkonium Compounds results in increased expression of IL1A protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein 		CTD PMID:8006454 PMID:12781210 PMID:25290854 PMID:30240708 PMID:30517752 More... NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions 		ISO Benzalkonium Compounds results in increased expression of IL1B protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein 		CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1f10 interleukin 1 family member 10 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA CTD PMID:30171875 NCBI chr 3:27,470,798...27,473,726
Ensembl chr 3:27,470,798...27,473,726 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL23A mRNA CTD PMID:30171875 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il24 interleukin 24 increases expression ISO Benzalkonium Compounds results in increased expression of IL24 mRNA CTD PMID:37149095 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Il27 interleukin 27 increases expression ISO Benzalkonium Compounds results in increased expression of IL27 protein CTD PMID:30517752 NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:190,603,522...190,609,258 		JBrowse link
G Il3 interleukin 3 increases expression ISO Benzalkonium Compounds results in increased expression of IL3 protein CTD PMID:30517752 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Il31 interleukin 31 increases expression ISO Benzalkonium Compounds results in increased expression of IL31 protein CTD PMID:30517752 NCBI chr12:38,756,231...38,765,917
Ensembl chr12:38,762,870...38,765,921 		JBrowse link
G Il31ra interleukin 31 receptor A decreases expression ISO Benzalkonium Compounds results in decreased expression of IL31RA mRNA CTD PMID:30171875 NCBI chr 2:45,851,073...45,922,300
Ensembl chr 2:45,855,868...45,917,009 		JBrowse link
G Il34 interleukin 34 decreases expression ISO Benzalkonium Compounds results in decreased expression of IL34 mRNA CTD PMID:30171875 NCBI chr19:55,624,368...55,690,576
Ensembl chr19:55,624,369...55,673,376 		JBrowse link
G Il36a interleukin 36, alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL36A mRNA CTD PMID:30171875 NCBI chr 3:27,395,146...27,399,695
Ensembl chr 3:27,395,146...27,399,695 		JBrowse link
G Il36b interleukin 36, beta increases expression ISO Benzalkonium Compounds results in increased expression of IL36B mRNA CTD PMID:30171875 NCBI chr 3:27,422,980...27,521,344
Ensembl chr 3:27,423,171...27,428,678 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO Benzalkonium Compounds results in increased expression of IL36G mRNA CTD PMID:30171875 NCBI chr 3:27,346,675...27,352,839
Ensembl chr 3:27,346,670...27,352,834 		JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions 		ISO Benzalkonium Compounds results in increased expression of IL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein 		CTD PMID:30517752 PMID:31158415 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 increases expression ISO Benzalkonium Compounds results in increased expression of IL5 protein CTD PMID:30517752 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 increases secretion
increases expression
multiple interactions
affects response to substance 		ISO Benzalkonium Compounds results in increased secretion of IL6 protein
Benzalkonium Compounds results in increased expression of IL6 mRNA
Benzalkonium Compounds results in increased expression of and results in increased secretion of IL6 protein
Benzalkonium Compounds results in increased expression of IL6 mRNA; Benzalkonium Compounds results in increased expression of IL6 protein
IL6 protein affects the susceptibility to Benzalkonium Compounds
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GSDMA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-9B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MRGPRA2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF26 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein 		CTD PMID:17763283 PMID:28214551 PMID:29953848 PMID:30171875 PMID:30517752 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor multiple interactions
increases response to substance 		ISO [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein CTD PMID:31158415 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Benzalkonium Compounds results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027 		JBrowse link
G Inhba inhibin subunit beta A increases expression ISO Benzalkonium Compounds results in increased expression of INHBA mRNA CTD PMID:30171875 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Benzalkonium Compounds results in increased expression of INSIG1 mRNA CTD PMID:31199489 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Isl1 ISL LIM homeobox 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ISL1 mRNA CTD PMID:30171875 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Benzalkonium Compounds inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kdm7a lysine demethylase 7A increases expression ISO Benzalkonium Compounds results in increased expression of KDM7A mRNA CTD PMID:37149095 NCBI chr 4:68,866,263...68,992,979
Ensembl chr 4:68,871,677...68,931,506 		JBrowse link
G Kdm8 lysine demethylase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of KDM8 mRNA CTD PMID:31199489 NCBI chr 1:189,444,527...189,459,507
Ensembl chr 1:189,444,555...189,459,491 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of KLF2 mRNA CTD PMID:37149095 NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768 		JBrowse link
G Klk8 kallikrein related-peptidase 8 increases expression ISO Benzalkonium Compounds results in increased expression of KLK8 mRNA CTD PMID:30171875 NCBI chr 1:103,388,352...103,395,195
Ensembl chr 1:103,388,352...103,395,195 		JBrowse link
G Krt2 keratin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA CTD PMID:30171875 NCBI chr 7:134,819,584...134,826,736
Ensembl chr 7:134,819,584...134,827,011 		JBrowse link
G Krtap14 keratin associated protein 14 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA CTD PMID:30171875 NCBI chr11:41,612,876...41,613,718
Ensembl chr11:41,612,876...41,613,718 		JBrowse link
G Lce1m late cornified envelope 1M decreases expression ISO Benzalkonium Compounds results in decreased expression of LCE1M mRNA CTD PMID:30171875 NCBI chr 2:181,333,098...181,334,300
Ensembl chr 2:181,333,098...181,334,300 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Benzalkonium Compounds results in decreased expression of LDHA mRNA CTD PMID:31199489 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Benzalkonium Compounds results in increased expression of LIF protein CTD PMID:30517752 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G LOC120097198 U6 spliceosomal RNA decreases expression ISO Benzalkonium Compounds results in decreased expression of RNU6-643P CTD PMID:37149095 NCBI chr15:105,897,695...105,897,798
Ensembl chr15:105,897,695...105,897,798 		JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of LOXL1 mRNA CTD PMID:31199489 NCBI chr 8:67,587,636...67,612,224
Ensembl chr 8:67,587,636...67,612,224 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Benzalkonium Compounds results in increased expression of LST1 mRNA CTD PMID:30171875 NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,639,341...3,642,669 		JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA CTD PMID:30171875 NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Benzalkonium Compounds results in increased phosphorylation of MAPK14 protein CTD PMID:15737199 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of MESP2 mRNA CTD PMID:30171875 NCBI chr 1:143,165,914...143,168,520
Ensembl chr 1:143,165,849...143,168,511 		JBrowse link
G Mif macrophage migration inhibitory factor increases secretion ISO Benzalkonium Compounds results in increased secretion of MIF protein CTD PMID:31707104 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Benzalkonium Compounds results in increased expression of MMP10 mRNA CTD PMID:30806763 NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Benzalkonium Compounds results in increased expression of MMP12 mRNA CTD PMID:30171875 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity EXP Benzalkonium Compounds results in increased activity of MMP2 protein CTD PMID:21058936 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp25 matrix metallopeptidase 25 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA CTD PMID:30171875 NCBI chr10:13,164,974...13,180,503
Ensembl chr10:13,164,977...13,180,503 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity 		ISO
EXP 		[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA
Benzalkonium Compounds results in increased activity of MMP9 protein 		CTD PMID:21058936 PMID:30171875 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Benzalkonium Compounds results in increased expression of MSMO1 mRNA CTD PMID:31199489 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445 		JBrowse link
G Msx2 msh homeobox 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA CTD PMID:30171875 NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945 		JBrowse link
G Mt2 metallothionein 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of MT2 mRNA CTD PMID:31199489 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Benzalkonium Compounds results in decreased expression of MTHFD2 mRNA CTD PMID:31199489 NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350 		JBrowse link
G Mylk3 myosin light chain kinase 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA CTD PMID:30171875 NCBI chr19:37,858,298...37,916,805
Ensembl chr19:37,865,141...37,915,827 		JBrowse link
G Ndufa4 Ndufa4, mitochondrial complex associated decreases expression ISO Benzalkonium Compounds results in decreased expression of NDUFA4 mRNA CTD PMID:31199489 NCBI chr 4:40,968,391...40,975,559
Ensembl chr 4:40,968,391...40,975,559 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Benzalkonium Compounds results in increased expression of NR4A2 mRNA CTD PMID:25377654 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769 		JBrowse link
G Nrg2 neuregulin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA CTD PMID:30171875 NCBI chr18:27,890,578...28,072,538
Ensembl chr18:27,890,578...28,072,538 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 affects response to substance ISO NTRK3 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004 		JBrowse link
G Ocln occludin decreases expression ISO Benzalkonium Compounds results in decreased expression of OCLN protein CTD PMID:29514330 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ODC1 mRNA CTD PMID:31199489 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of OLR1 mRNA CTD PMID:30171875 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598 		JBrowse link
G Orm1 orosomucoid 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ORM1 mRNA CTD PMID:30171875 NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:81,788,395...81,791,667 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions 		ISO Benzalkonium Compounds analog results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of PARP1 protein] 		CTD PMID:31982400 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pbk PDZ binding kinase increases expression ISO Benzalkonium Compounds results in increased expression of PBK mRNA CTD PMID:30171875 NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO Benzalkonium Compounds results in decreased expression of PCSK9 mRNA CTD PMID:31199489 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pdcd1 programmed cell death 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA CTD PMID:30171875 NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:101,866,126...101,879,270 		JBrowse link
G Pfdn6 prefoldin subunit 6 affects response to substance ISO PFDN6 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,947,844...4,949,318
Ensembl chr20:4,947,844...4,949,318 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 increases expression ISO Benzalkonium Compounds results in increased expression of PGLYRP3 mRNA CTD PMID:30171875 NCBI chr 2:180,174,931...180,186,007
Ensembl chr 2:179,201,527...179,219,994
Ensembl chr 2:179,201,527...179,219,994 		JBrowse link
G Pgp phosphoglycolate phosphatase increases expression ISO Benzalkonium Compounds results in increased expression of PGP mRNA CTD PMID:31199489 NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408 		JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression ISO Benzalkonium Compounds results in decreased expression of PLA2G5 mRNA CTD PMID:30171875 NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:156,324,629...156,381,926 		JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 increases expression ISO Benzalkonium Compounds results in increased expression of PLCXD3 mRNA CTD PMID:31199489 NCBI chr 2:55,294,597...55,473,968
Ensembl chr 2:55,294,613...55,474,220 		JBrowse link
G Plk2 polo-like kinase 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of PLK2 mRNA CTD PMID:37149095 NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of PNPLA2 mRNA CTD PMID:31199489 NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359 		JBrowse link
G Polr1d RNA polymerase I and III subunit D decreases expression ISO Benzalkonium Compounds results in decreased expression of POLR1D mRNA CTD PMID:31199489 NCBI chr12:13,084,505...13,118,069
Ensembl chr12:13,084,512...13,095,627 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Benzalkonium Compounds results in decreased expression of PPARA mRNA CTD PMID:31199489 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAA2 mRNA CTD PMID:31199489 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAG2 mRNA CTD PMID:31199489 NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939 		JBrowse link
G Prokr2 prokineticin receptor 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA CTD PMID:30171875 NCBI chr 3:140,077,629...140,092,327
Ensembl chr 3:140,077,630...140,092,093 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of PTGS2 mRNA CTD PMID:30806763 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA CTD PMID:30171875 NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372 		JBrowse link
G Ralgdsl2 ral guanine nucleotide dissociation stimulator like 2 affects response to substance ISO RGL2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,950,379...4,958,315
Ensembl chr20:4,950,381...4,958,135 		JBrowse link
G Reg1a regenerating family member 1 alpha multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA CTD PMID:30171875 NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585 		JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA CTD PMID:30171875 NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738 		JBrowse link
G Rps18 ribosomal protein S18 affects response to substance ISO RPS18 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,933,741...4,937,423
Ensembl chr20:4,917,095...4,937,423 		JBrowse link
G RT1-DOa RT1 class II, locus DOa affects response to substance ISO HLA-DOA SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,755,287...4,758,491
Ensembl chr20:4,755,499...4,758,478 		JBrowse link
G RT1-DOb RT1 class II, locus DOb affects response to substance ISO HLA-DOB SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,621,336...4,627,537
Ensembl chr20:4,619,694...4,627,523 		JBrowse link
G RT1-Ha RT1 class II, locus Ha affects response to substance ISO HLA-DPA1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141 		JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 affects response to substance ISO HLA-DPB1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,777,494...4,781,486
Ensembl chr20:4,776,547...4,781,574 		JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA CTD PMID:30171875 NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression
decreases expression 		ISO Benzalkonium Compounds results in increased expression of SCD mRNA
Benzalkonium Compounds results in decreased expression of SCD1 mRNA 		CTD PMID:29155129 PMID:31199489 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Serpinb13 serpin family B member 13 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA CTD PMID:30171875 NCBI chr13:23,633,220...23,665,100
Ensembl chr13:23,633,220...23,664,994 		JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SERPINE1 mRNA CTD PMID:30171875 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sesn2 sestrin 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of SESN2 mRNA CTD PMID:31199489 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255 		JBrowse link
G Sfn stratifin increases expression ISO Benzalkonium Compounds results in increased expression of SFN mRNA CTD PMID:30171875 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of SFRP4 mRNA CTD PMID:30171875 NCBI chr17:49,974,532...50,026,448
Ensembl chr17:50,015,812...50,026,395 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SLC16A1 mRNA CTD PMID:31199489 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Benzalkonium Compounds results in increased expression of SLC7A11 mRNA CTD PMID:30806763 PMID:37149095 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Snora38 small nucleolar RNA, H/ACA box 38 decreases expression ISO Benzalkonium Compounds results in decreased expression of SNORA38 CTD PMID:37149095 NCBI chr 9:22,077,872...22,077,996 JBrowse link
G Snora71d small nucleolar RNA, H/ACA box 71D decreases expression ISO Benzalkonium Compounds results in decreased expression of SNORA71D mRNA CTD PMID:25377654 NCBI chr 1:241,544,327...241,544,458
Ensembl chr 1:241,544,327...241,544,458 		JBrowse link
G Sox21 SRY-box transcription factor 21 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA CTD PMID:30171875 NCBI chr15:101,699,580...101,703,175
Ensembl chr15:101,674,512...101,819,980 		JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1A mRNA CTD PMID:30171875 NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991 		JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1B mRNA CTD PMID:30171875 NCBI chr 2:180,704,457...180,706,355
Ensembl chr 2:180,704,457...180,706,355 		JBrowse link
G Sprr2a small proline rich protein 2A increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2H mRNA CTD PMID:30171875 NCBI chr 2:180,511,568...180,511,840 JBrowse link
G Sprr2b small proline rich protein 2B increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2B mRNA CTD PMID:30171875 NCBI chr 2:180,548,428...180,548,700 JBrowse link
G Sprr2f small proline rich protein 2F increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2F mRNA CTD PMID:30171875 NCBI chr 2:180,685,587...180,685,817
Ensembl chr 2:180,685,587...180,685,817 		JBrowse link
G Sqle squalene epoxidase increases expression ISO Benzalkonium Compounds results in increased expression of SQLE mRNA CTD PMID:31199489 NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of SREBF2 mRNA CTD PMID:26919959 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Srms src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA CTD PMID:30171875 NCBI chr 3:188,696,070...188,702,474
Ensembl chr 3:188,696,071...188,702,474 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA CTD PMID:30171875 NCBI chr 8:37,798,994...37,839,881
Ensembl chr 8:37,798,995...37,855,652 		JBrowse link
G Tapbp TAP binding protein affects response to substance ISO TAPBP SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,958,821...4,967,958
Ensembl chr20:4,959,926...4,971,834 		JBrowse link
G Tfap2b transcription factor AP-2 beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA CTD PMID:30171875 NCBI chr 9:29,282,703...29,312,568
Ensembl chr 9:29,282,825...29,312,568 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Benzalkonium Compounds results in increased expression of TGFB1 protein CTD PMID:30517752 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgm3 transglutaminase 3 increases expression ISO Benzalkonium Compounds results in increased expression of TGM3 mRNA CTD PMID:30171875 NCBI chr 3:137,681,809...137,717,219
Ensembl chr 3:137,681,809...137,717,219 		JBrowse link
G Tgm7 transglutaminase 7 decreases expression ISO Benzalkonium Compounds results in decreased expression of TGM7 mRNA CTD PMID:30171875 NCBI chr 3:128,505,638...128,523,298
Ensembl chr 3:128,505,650...128,529,939 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Benzalkonium Compounds results in increased expression of THBS1 mRNA CTD PMID:30171875 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of TLR1 mRNA CTD PMID:30171875 NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,740,379...43,756,243 		JBrowse link
G Tlr4 toll-like receptor 4 increases activity ISO Benzalkonium Compounds results in increased activity of TLR4 protein CTD PMID:29514330 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tmprss11b transmembrane serine protease 11B increases expression ISO Benzalkonium Compounds results in increased expression of TMPRSS11B mRNA CTD PMID:30171875 NCBI chr14:21,738,760...21,763,896
Ensembl chr14:21,738,760...21,762,107 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression 		ISO Benzalkonium Compounds results in decreased secretion of TNF protein
Benzalkonium Compounds results in increased expression of TNF mRNA; Benzalkonium Compounds results in increased expression of TNF protein 		CTD PMID:29953848 PMID:30171875 PMID:30517752 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Benzalkonium Compounds results in increased expression of TNFAIP6 mRNA CTD PMID:30171875 NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA CTD PMID:30171875 NCBI chr 7:115,616,139...115,618,647
Ensembl chr 7:115,616,303...115,618,620 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Benzalkonium Compounds results in increased expression of TNFRSF9 mRNA CTD PMID:30171875 NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:166,664,494...166,690,831 		JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA CTD PMID:30171875 NCBI chr 5:82,266,436...82,292,858
Ensembl chr 5:82,266,436...82,292,858 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Benzalkonium Compounds results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of TPI1 mRNA CTD PMID:31199489 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 increases expression ISO Benzalkonium Compounds results in increased expression of TREM2 mRNA CTD PMID:30171875 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Benzalkonium Compounds results in increased expression of TRIB3 mRNA CTD PMID:37149095 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802 		JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA CTD PMID:30171875 NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420 		JBrowse link
G Ulbp1 UL16 binding protein 1 increases expression ISO Benzalkonium Compounds results in increased expression of ULBP1 mRNA CTD PMID:37149095 NCBI chr 1:3,506,106...3,527,982 JBrowse link
G Upk3b uroplakin 3B decreases expression ISO Benzalkonium Compounds results in decreased expression of UPK3B mRNA CTD PMID:30171875 NCBI chr12:26,266,838...26,274,240
Ensembl chr12:26,266,838...26,274,240 		JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII decreases expression ISO Benzalkonium Compounds results in decreased expression of UQCRQ mRNA CTD PMID:31199489 NCBI chr10:38,086,691...38,093,871
Ensembl chr10:38,087,715...38,089,996 		JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO Benzalkonium Compounds results in increased expression of VEGFD mRNA CTD PMID:20146380 NCBI chr  X:33,704,582...33,740,305
Ensembl chr  X:33,706,055...33,740,167 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA CTD PMID:30171875 NCBI chr 2:190,942,224...191,010,280
Ensembl chr 2:190,942,224...191,010,280 		JBrowse link
G Wdr46 WD repeat domain 46 affects response to substance ISO WDR46 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,939,721...4,947,619
Ensembl chr20:4,939,732...4,947,741 		JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XBP1 mRNA alternative form CTD PMID:28236482 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XCL1 mRNA CTD PMID:30171875 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:79,781,784...79,785,440 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        detergent 772
          benzalkonium chloride 254
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic ion 11556
                              organic cation 9047
                                quaternary ammonium ion 5332
                                  quaternary nitrogen compound 920
                                    quaternary ammonium salt 588
                                      benzalkonium chloride 254
paths to the root