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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:arsonite(2-)
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Accession:CHEBI:29753 term browser browse the term
Definition:An arsenic oxoanion that has formula AsHO2.
Synonyms:exact_synonym: arsonite;   hydridodioxidoarsenate(2-)
 related_synonym: Formula=AsHO2;   InChI=1S/AsHO2/c2-1-3/h1H/q-2;   InChIKey=MPBCULOORJNCSW-UHFFFAOYSA-N;   SMILES=[H][As]([O-])[O-];   [AsHO2](2-)
 cyclic_relationship: is_conjugate_base_of CHEBI:33410



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methylarsonite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase multiple interactions
increases chemical synthesis
ISO Cysteine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; Glutathione promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite] CTD PMID:22955273 NCBI chr 1:245,595,939...245,628,921 JBrowse link
G Gys2 glycogen synthase 2 multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in increased activity of GYS2 protein] CTD PMID:28952001 NCBI chr 4:175,365,054...175,406,228 JBrowse link
G Ins1 insulin 1 multiple interactions ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; methylarsonite inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Glucose results in increased secretion of INS1 protein]]; methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]; methylarsonite inhibits the reaction [Potassium Chloride results in increased secretion of INS1 protein]; Tolbutamide inhibits the reaction [methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31332465 NCBI chr 1:261,186,119...261,186,686 JBrowse link
G Ins2 insulin 2 multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in decreased activity of PYGL protein]; methylarsonite inhibits the reaction [INS protein results in increased activity of GYS2 protein] CTD PMID:28952001 NCBI chr 1:207,272,738...207,421,998 JBrowse link
G Pygl glycogen phosphorylase L multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in decreased activity of PYGL protein] CTD PMID:28952001 NCBI chr 6:94,433,558...94,476,219 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      atom 19896
        metalloid atom 15411
          arsenic atom 14703
            arsenic molecular entity 14703
              arsenic oxoanion 6352
                arsonite(2-) 5
                  methylarsonite 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      chalcogen 19587
                        oxygen atom 19559
                          oxygen molecular entity 19559
                            oxide 12887
                              oxoanion 10465
                                pnictogen oxoanion 6506
                                  arsenic oxoanion 6352
                                    arsonite(2-) 5
                                      methylarsonite 5
paths to the root