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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:arsonite(2-)
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Accession:CHEBI:29753 term browser browse the term
Definition:An arsenic oxoanion that has formula AsHO2.
Synonyms:exact_synonym: arsonite;   hydridodioxidoarsenate(2-)
 related_synonym: Formula=AsHO2;   InChI=1S/AsHO2/c2-1-3/h1H/q-2;   InChIKey=MPBCULOORJNCSW-UHFFFAOYSA-N;   SMILES=[H][As]([O-])[O-];   [AsHO2](2-)
 cyclic_relationship: is_conjugate_base_of CHEBI:33410



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methylarsonite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AS3MT arsenite methyltransferase multiple interactions
increases chemical synthesis
EXP Cysteine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; Glutathione promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite] CTD PMID:22955273 NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899
JBrowse link
G GYS2 glycogen synthase 2 multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in increased activity of GYS2 protein] CTD PMID:28952001 NCBI chr12:21,532,577...21,604,847
Ensembl chr12:21,536,107...21,604,847
JBrowse link
G INS insulin multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in decreased activity of PYGL protein]; methylarsonite inhibits the reaction [INS protein results in increased activity of GYS2 protein] CTD PMID:28952001 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; methylarsonite inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Glucose results in increased secretion of INS1 protein]]; methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]; methylarsonite inhibits the reaction [Potassium Chloride results in increased secretion of INS1 protein]; Tolbutamide inhibits the reaction [methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31332465 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
JBrowse link
G PYGL glycogen phosphorylase L multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in decreased activity of PYGL protein] CTD PMID:28952001 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26503
    chemical entity 26483
      atom 26479
        metalloid atom 18061
          arsenic atom 17133
            arsenic molecular entity 17133
              arsenic oxoanion 6639
                arsonite(2-) 5
                  methylarsonite 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 26503
    subatomic particle 26479
      composite particle 26479
        hadron 26479
          baryon 26479
            nucleon 26479
              atomic nucleus 26479
                atom 26479
                  main group element atom 26217
                    p-block element atom 26217
                      chalcogen 25128
                        oxygen atom 24935
                          oxygen molecular entity 24935
                            oxide 13916
                              oxoanion 11025
                                pnictogen oxoanion 6795
                                  arsenic oxoanion 6639
                                    arsonite(2-) 5
                                      methylarsonite 5
paths to the root