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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-(indol-3-yl)pyruvic acid
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Accession:CHEBI:29750 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is pyruvic acid substituted by a 1H-indol-3-yl group at position 3. It has been found in Lycopersicon esculentum
Synonyms:related_synonym: 3-(1H-indol-3-yl)-2-oxopropanoic acid;   Formula=C11H9NO3;   InChI=1S/C11H9NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H,14,15);   InChIKey=RSTKLPZEZYGQPY-UHFFFAOYSA-N;   Indolepyruvic acid;   SMILES=OC(=O)C(=O)Cc1c[nH]c2ccccc12;   indole-3-pyruvic acid
 alt_id: CHEBI:24817;   CHEBI:39967;   CHEBI:5917
 xref: CAS:392-12-1;   ECMDB:ECMDB21543;   HMDB:HMDB0060484;   KEGG:C00331;   KNApSAcK:C00007571
 xref_mesh: MESH:C008122
 xref: PDBeChem:3IO;   PMID:12902239;   PMID:24445491;   PMID:25036485;   Reaxys:172966;   YMDB:YMDB00169
 cyclic_relationship: is_conjugate_acid_of CHEBI:17640


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3-(indol-3-yl)pyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR protein affects the reaction [[indol-3-yl pyruvic acid co-treated with erastin] results in increased expression of SLC7A11 protein] CTD PMID:38641223 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO indol-3-yl pyruvic acid results in increased expression of CYP1A2 mRNA CTD PMID:38641223 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[indol-3-yl pyruvic acid co-treated with erastin] results in increased expression of SLC7A11 protein]; [indol-3-yl pyruvic acid co-treated with erastin] results in increased expression of SLC7A11 protein; AHR protein affects the reaction [[indol-3-yl pyruvic acid co-treated with erastin] results in increased expression of SLC7A11 protein] CTD PMID:38641223 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          cofactor 16568
            pyruvic acid 53
              3-(indol-3-yl)pyruvic acid 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      monocarboxylic acid 18000
                                        fatty acid 16833
                                          saturated fatty acid 16556
                                            propionic acid 3873
                                              pyruvic acid 53
                                                3-(indol-3-yl)pyruvic acid 3
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