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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:kresoxim-methyl
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Accession:CHEBI:2962 term browser browse the term
Definition:A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.
Synonyms:exact_synonym: methyl (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetate
 related_synonym: BAS 490 F;   Formula=C18H19NO4;   InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+;   InChIKey=ZOTBXTZVPHCKPN-HTXNQAPBSA-N;   Methyl (E)-alpha-(methoxyimino)-2-((2-methylphenoxy)methyl)benzeneacetate;   SMILES=CO\\N=C(\\C(=O)OC)c1ccccc1COc1ccccc1C;   methyl (E)-methoxyimino[alpha-(o-tolyloxy)-o-tolyl]acetate;   methyl (alphaE)-alpha-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetate
 xref: CAS:143390-89-0;   KEGG:C11017
 xref_mesh: MESH:C469328
 xref: PMID:23197469;   PMID:23277369;   PMID:23452212;   PMID:24061350;   PMID:24210350;   PMID:24611510;   PMID:24936710;   PMID:24997920;   PPDB:414;   Pesticides:kresoxim-methyl;   Reaxys:8330581


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kresoxim-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 multiple interactions ISO kresoxim-methyl inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:30818834 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO kresoxim-methyl inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]; kresoxim-methyl inhibits the reaction [XCT790 results in decreased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity ISO kresoxim-methyl results in decreased activity of GPX1 protein CTD PMID:30064279 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO kresoxim-methyl results in increased activity of NFE2L2 protein CTD PMID:30818834 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO kresoxim-methyl inhibits the reaction [Promegestone results in increased activity of PGR protein] CTD PMID:30818834 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO kresoxim-methyl inhibits the reaction [Rosiglitazone results in increased activity of PPARG protein] CTD PMID:30818834 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO kresoxim-methyl inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO kresoxim-methyl binds to THRB protein CTD PMID:28973306 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Tp53 tumor protein p53 increases activity ISO kresoxim-methyl results in increased activity of TP53 protein CTD PMID:30818834 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        xenobiotic 19528
          kresoxim-methyl 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      chalcogen 20491
                        oxygen atom 20457
                          oxygen molecular entity 20457
                            hydroxides 20230
                              organic hydroxy compound 19765
                                alcohol 16148
                                  aliphatic alcohol 12648
                                    alkyl alcohol 12572
                                      methanol 4014
                                        methyl ester 3961
                                          kresoxim-methyl 9
paths to the root