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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phosgene
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Accession:CHEBI:29365 term browser browse the term
Definition:An acyl chloride obtained by substitution of both hydrogens of formaldehyde by chlorine.
Synonyms:related_synonym: COCl2;   Carbon dichloride oxide;   Carbon oxychloride;   Carbone (oxychlorure de);   Carbonic acid dichloride;   Carbonic chloride;   Carbonic dichloride;   Carbonyl chloride;   Carbonyl dichloride;   Carbonylchlorid;   Chloroformyl chloride;   Dichloroformaldehyde;   Formula=CCl2O;   Fosgeen;   Fosgen;   InChI=1S/CCl2O/c2-1(3)4;   InChIKey=YGYAWVDWMABLBF-UHFFFAOYSA-N;   Phosgen;   SMILES=ClC(Cl)=O
 xref: CAS:75-44-5
 xref_mesh: MESH:D010705
 xref: PMID:21031186;   PMID:21222562;   PMID:21293301;   PMID:21309662;   Reaxys:1098367


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phosgene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 affects expression ISO Phosgene affects the expression of ADCY6 mRNA CTD PMID:16300373 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Adcy8 adenylate cyclase 8 affects expression ISO Phosgene affects the expression of ADCY8 mRNA CTD PMID:16300373 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Adss2 adenylosuccinate synthase 2 affects expression ISO Phosgene affects the expression of ADSS2 mRNA CTD PMID:16300373 NCBI chr13:89,769,240...89,799,577
Ensembl chr13:89,769,244...89,799,604 		JBrowse link
G Alb albumin affects expression ISO Phosgene affects the expression of ALB1 mRNA CTD PMID:16300373 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Anxa1 annexin A1 affects expression ISO Phosgene affects the expression of ANXA1 mRNA CTD PMID:16300373 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Aplnr apelin receptor affects expression ISO Phosgene affects the expression of APLNR mRNA CTD PMID:16300373 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Areg amphiregulin affects expression ISO Phosgene affects the expression of AREG mRNA CTD PMID:16300373 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arg2 arginase 2 affects expression ISO Phosgene affects the expression of ARG2 mRNA CTD PMID:16300373 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arrb1 arrestin, beta 1 affects expression ISO Phosgene affects the expression of ARRB1 mRNA CTD PMID:16300373 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) affects expression ISO Phosgene affects the expression of ASNS mRNA CTD PMID:16300373 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf3 activating transcription factor 3 affects expression ISO Phosgene affects the expression of ATF3 mRNA CTD PMID:16300373 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H affects expression ISO Phosgene affects the expression of ATP6V1H mRNA CTD PMID:16300373 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962 		JBrowse link
G Axin2 axin 2 affects expression ISO Phosgene affects the expression of AXIN2 mRNA CTD PMID:16300373 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor affects expression ISO Phosgene affects the expression of BCL10 mRNA CTD PMID:16300373 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO Phosgene affects the expression of BHLHE40 mRNA CTD PMID:16300373 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Blvrb biliverdin reductase B affects expression ISO Phosgene affects the expression of BLVRB mRNA CTD PMID:16300373 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Bmp6 bone morphogenetic protein 6 affects expression ISO Phosgene affects the expression of BMP6 mRNA CTD PMID:16300373 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Car4 carbonic anhydrase 4 affects expression ISO Phosgene affects the expression of CAR4 mRNA CTD PMID:16300373 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501 		JBrowse link
G Casp1 caspase 1 increases expression
multiple interactions		 EXP Phosgene results in increased expression of CASP1 mRNA
NLRP3 protein promotes the reaction [Phosgene results in increased expression of and results in increased activity of CASP1 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of CASP1 mRNA]; Phosgene results in increased expression of and results in increased activity of CASP1 protein		 CTD PMID:33012731 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cbr3 carbonyl reductase 3 affects expression ISO Phosgene affects the expression of CBR3 mRNA CTD PMID:16300373 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO Phosgene affects the expression of CCN1 mRNA CTD PMID:16300373 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO Phosgene affects the expression of CDKN1A mRNA CTD PMID:16300373 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression ISO Phosgene affects the expression of CDKN2C mRNA CTD PMID:16300373 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta affects expression ISO Phosgene affects the expression of CEBPD mRNA CTD PMID:16300373 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Cers4 ceramide synthase 4 affects expression ISO Phosgene affects the expression of CERS4 mRNA CTD PMID:16300373 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Ch25h cholesterol 25-hydroxylase affects expression ISO Phosgene affects the expression of CH25H mRNA CTD PMID:16300373 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Cldn4 claudin 4 affects expression ISO Phosgene affects the expression of CLDN4 mRNA CTD PMID:16300373 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Csk C-terminal Src kinase affects expression ISO Phosgene affects the expression of CSK mRNA CTD PMID:16300373 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Cstb cystatin B affects expression ISO Phosgene affects the expression of CSTB mRNA CTD PMID:16300373 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Ctps1 CTP synthase 1 affects expression ISO Phosgene affects the expression of CTPS1 mRNA CTD PMID:16300373 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Cttn cortactin affects expression ISO Phosgene affects the expression of CTTN mRNA CTD PMID:16300373 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO Phosgene affects the expression of CXCR4 mRNA CTD PMID:16300373 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 affects expression ISO Phosgene affects the expression of CXCR5 mRNA CTD PMID:16300373 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cyp51 cytochrome P450, family 51 affects expression ISO Phosgene affects the expression of CYP51 mRNA CTD PMID:16300373 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Ddx39a DExD-box helicase 39A affects expression ISO Phosgene affects the expression of DDX39A mRNA CTD PMID:16300373 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954 		JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 affects expression ISO Phosgene affects the expression of DNAJC2 mRNA CTD PMID:16300373 NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431 		JBrowse link
G Edn1 endothelin 1 increases expression EXP Phosgene results in increased expression of EDN1 protein CTD PMID:18645720 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egr1 early growth response 1 affects expression ISO Phosgene affects the expression of EGR1 mRNA CTD PMID:16300373 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 affects expression ISO Phosgene affects the expression of EGR2 mRNA CTD PMID:16300373 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A affects expression ISO Phosgene affects the expression of EIF1A mRNA CTD PMID:16300373 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696 		JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta affects expression ISO Phosgene affects the expression of EIF2S2 mRNA CTD PMID:16300373 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432 		JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 affects expression ISO Phosgene affects the expression of EIF4G3 mRNA CTD PMID:16300373 NCBI chr 5:150,197,410...150,418,862
Ensembl chr 5:150,195,226...150,418,363 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 affects expression ISO Phosgene affects the expression of EIF5 mRNA CTD PMID:16300373 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Elk3 ETS transcription factor ELK3 affects expression ISO Phosgene affects the expression of ELK3 mRNA CTD PMID:16300373 NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 affects expression ISO Phosgene affects the expression of ELL2 mRNA CTD PMID:16300373 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781 		JBrowse link
G Epha2 Eph receptor A2 affects expression ISO Phosgene affects the expression of EPHA2 mRNA CTD PMID:16300373 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ereg epiregulin affects expression ISO Phosgene affects the expression of EREG mRNA CTD PMID:16300373 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Esd esterase D affects expression ISO Phosgene affects the expression of ESD mRNA CTD PMID:16300373 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G F3 coagulation factor III, tissue factor affects expression ISO Phosgene affects the expression of F3 mRNA CTD PMID:16300373 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fbln5 fibulin 5 affects expression ISO Phosgene affects the expression of FBLN5 mRNA CTD PMID:16300373 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression ISO Phosgene affects the expression of FDFT1 mRNA CTD PMID:16300373 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdx1 ferredoxin 1 affects expression ISO Phosgene affects the expression of FDX1 mRNA CTD PMID:16300373 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects expression ISO Phosgene affects the expression of FGFR4 mRNA CTD PMID:16300373 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression
affects expression		 EXP
ISO		 Phosgene results in decreased expression of FLT1 mRNA; Phosgene results in decreased expression of FLT1 protein
Phosgene affects the expression of FLT1 protein		 CTD PMID:15256155 PMID:18645720 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression ISO Phosgene affects the expression of FMO1 mRNA CTD PMID:16300373 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 affects expression ISO Phosgene affects the expression of FMO5 mRNA CTD PMID:16300373 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO Phosgene affects the expression of FOS mRNA CTD PMID:16300373 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fzd2 frizzled class receptor 2 affects expression ISO Phosgene affects the expression of FZD2 mRNA CTD PMID:16300373 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma affects expression ISO Phosgene affects the expression of GADD45G mRNA CTD PMID:16300373 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 affects expression ISO Phosgene affects the expression of GALNT3 mRNA CTD PMID:16300373 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression ISO Phosgene affects the expression of GCLC mRNA CTD PMID:16300373 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression ISO Phosgene affects the expression of GCLM mRNA CTD PMID:16300373 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 affects expression ISO Phosgene affects the expression of GDF15 mRNA CTD PMID:16300373 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression ISO Phosgene affects the expression of GPX2 mRNA CTD PMID:16300373 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gtf2i general transcription factor II I affects expression ISO Phosgene affects the expression of GTF2I mRNA CTD PMID:16300373 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243 		JBrowse link
G Hdac5 histone deacetylase 5 affects expression ISO Phosgene affects the expression of HDAC5 mRNA CTD PMID:16300373 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hip1 huntingtin interacting protein 1 affects expression ISO Phosgene affects the expression of HIP1 mRNA CTD PMID:16300373 NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 affects expression ISO Phosgene affects the expression of HIPK2 mRNA CTD PMID:16300373 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 affects expression ISO Phosgene affects the expression of HMGCS1 mRNA CTD PMID:16300373 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 affects expression
decreases activity		 ISO Phosgene affects the expression of HMOX1 mRNA
Phosgene results in decreased activity of HMOX1 protein		 CTD PMID:16300373 PMID:21945045 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Homer2 homer scaffold protein 2 affects expression ISO Phosgene affects the expression of HOMER2 mRNA CTD PMID:16300373 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Hoxa5 homeo box A5 affects expression ISO Phosgene affects the expression of HOXA5 mRNA CTD PMID:16300373 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression ISO Phosgene affects the expression of HSPA1A mRNA CTD PMID:16300373 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression ISO Phosgene affects the expression of HSPA9 mRNA CTD PMID:16300373 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Icam2 intercellular adhesion molecule 2 affects expression ISO Phosgene affects the expression of ICAM2 mRNA CTD PMID:16300373 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 affects expression ISO Phosgene affects the expression of IDI1 mRNA CTD PMID:16300373 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 affects expression ISO Phosgene affects the expression of IGFBP7 mRNA CTD PMID:16300373 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Il10 interleukin 10 increases expression EXP Phosgene results in increased expression of IL10 protein CTD PMID:33012731 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions		 EXP Phosgene results in increased expression of IL18 protein
NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL18 protein]		 CTD PMID:33012731 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP Phosgene results in increased expression of IL1B protein
NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL1B protein]		 CTD PMID:33012731 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma affects expression ISO Phosgene affects the expression of IL2RG mRNA CTD PMID:16300373 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression		 EXP NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL33 protein] CTD PMID:33012731 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 increases expression EXP Phosgene results in increased expression of IL4 protein CTD PMID:33012731 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Irs1 insulin receptor substrate 1 affects expression ISO Phosgene affects the expression of IRS1 mRNA CTD PMID:16300373 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression ISO Phosgene affects the expression of JUNB mRNA CTD PMID:16300373 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Jup junction plakoglobin affects expression ISO Phosgene affects the expression of JUP mRNA CTD PMID:16300373 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057 		JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 affects expression ISO Phosgene affects the expression of KCNA3 mRNA CTD PMID:16300373 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138 		JBrowse link
G Kdr kinase insert domain receptor affects expression
decreases expression		 ISO
EXP		 Phosgene affects the expression of KDR mRNA
Phosgene results in decreased expression of KDR mRNA; Phosgene results in decreased expression of KDR protein		 CTD PMID:16300373 PMID:18645720 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO Phosgene affects the expression of KIT mRNA CTD PMID:16300373 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klf5 KLF transcription factor 5 affects expression ISO Phosgene affects the expression of KLF5 mRNA CTD PMID:16300373 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Krt18 keratin 18 affects expression ISO Phosgene affects the expression of KRT18 mRNA CTD PMID:16300373 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt19 keratin 19 affects expression ISO Phosgene affects the expression of KRT19 mRNA CTD PMID:16300373 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt8 keratin 8 affects expression ISO Phosgene affects the expression of KRT8 mRNA CTD PMID:16300373 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Ldlr low density lipoprotein receptor affects expression ISO Phosgene affects the expression of LDLR mRNA CTD PMID:16300373 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lgals3 galectin 3 affects expression ISO Phosgene affects the expression of LGALS3 mRNA CTD PMID:16300373 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor affects expression ISO Phosgene affects the expression of LITAF mRNA CTD PMID:16300373 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Lrp2 LDL receptor related protein 2 affects expression ISO Phosgene affects the expression of LRP2 mRNA CTD PMID:16300373 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase affects expression ISO Phosgene affects the expression of LYN mRNA CTD PMID:16300373 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects expression ISO Phosgene affects the expression of MACF1 mRNA CTD PMID:16300373 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905 		JBrowse link
G Maff MAF bZIP transcription factor F affects expression ISO Phosgene affects the expression of MAFF mRNA CTD PMID:16300373 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK1 protein] CTD PMID:21818760 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK3 protein] CTD PMID:21818760 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 EXP Phosgene results in increased phosphorylation of MAPK8 protein
ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein]		 CTD PMID:21818760 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK9 protein] CTD PMID:21818760 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapt microtubule-associated protein tau affects expression ISO Phosgene affects the expression of MAPT mRNA CTD PMID:16300373 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 affects expression ISO Phosgene affects the expression of MBD1 mRNA CTD PMID:16300373 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mef2c myocyte enhancer factor 2C affects expression ISO Phosgene affects the expression of MEF2C mRNA CTD PMID:16300373 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 EXP Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 protein]
Phosgene results in increased expression of MMP9 mRNA; Phosgene results in increased expression of MMP9 protein		 CTD PMID:21941784 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mrc2 mannose receptor, C type 2 affects expression ISO Phosgene affects the expression of MRC2 mRNA CTD PMID:16300373 NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856 		JBrowse link
G Msn moesin affects expression ISO Phosgene affects the expression of MSN mRNA CTD PMID:16300373 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Mt1 metallothionein 1 affects expression ISO Phosgene affects the expression of MT1 mRNA CTD PMID:16300373 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A affects expression ISO Phosgene affects the expression of MT2 mRNA CTD PMID:16300373 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase affects expression ISO Phosgene affects the expression of MTHFD2 mRNA CTD PMID:16300373 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression ISO Phosgene affects the expression of MYC mRNA CTD PMID:16300373 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit affects expression ISO Phosgene affects the expression of NAA15 mRNA CTD PMID:16300373 NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 affects expression ISO Phosgene affects the expression of NCOR2 mRNA CTD PMID:16300373 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319 		JBrowse link
G Nfix nuclear factor I X affects expression ISO Phosgene affects the expression of NFIX mRNA CTD PMID:16300373 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nisch nischarin affects expression ISO Phosgene affects the expression of NISCH mRNA CTD PMID:16300373 NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression		 EXP NLRP3 protein promotes the reaction [Phosgene results in increased expression of and results in increased activity of CASP1 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of CASP1 mRNA]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL33 protein]; NLRP3 protein promotes the reaction [Phosgene results in increased expression of TNF protein]
Phosgene results in increased expression of NLRP3 mRNA; Phosgene results in increased expression of NLRP3 protein		 CTD PMID:33012731 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 affects response to substance
increases expression
multiple interactions		 ISO
EXP		 NOS2 affects the susceptibility to Phosgene
Phosgene results in increased expression of NOS2 mRNA; Phosgene results in increased expression of NOS2 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of NOS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of NOS2 protein]		 CTD PMID:21818760 PMID:25870319 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npnt nephronectin affects expression ISO Phosgene affects the expression of NPNT mRNA CTD PMID:16300373 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Npr2 natriuretic peptide receptor 2 affects expression ISO Phosgene affects the expression of NPR2 mRNA CTD PMID:16300373 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Phosgene affects the expression of NR3C1 mRNA CTD PMID:16300373 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Orc5 origin recognition complex, subunit 5 affects expression ISO Phosgene affects the expression of ORC5 mRNA CTD PMID:16300373 NCBI chr 4:12,548,007...12,612,611
Ensembl chr 4:12,548,007...12,612,568 		JBrowse link
G Osmr oncostatin M receptor affects expression ISO Phosgene affects the expression of OSMR mRNA CTD PMID:16300373 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Pdgfb platelet derived growth factor subunit B affects expression ISO Phosgene affects the expression of PDGFB mRNA CTD PMID:16300373 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression ISO Phosgene affects the expression of PDK4 mRNA CTD PMID:16300373 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pgd phosphogluconate dehydrogenase affects expression ISO Phosgene affects the expression of PGD mRNA CTD PMID:16300373 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pla2g2a phospholipase A2 group IIA increases activity EXP Phosgene results in increased activity of PLA2G2A protein CTD PMID:19235614 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression ISO Phosgene affects the expression of PLAUR mRNA CTD PMID:16300373 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 affects expression ISO Phosgene affects the expression of PLOD2 mRNA CTD PMID:16300373 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Pltp phospholipid transfer protein affects expression ISO Phosgene affects the expression of PLTP mRNA CTD PMID:16300373 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Prdm1 PR/SET domain 1 affects expression ISO Phosgene affects the expression of PRDM1 mRNA CTD PMID:16300373 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prx periaxin affects expression ISO Phosgene affects the expression of PRX mRNA CTD PMID:16300373 NCBI chr 1:82,785,082...82,807,154
Ensembl chr 1:82,786,815...82,807,407 		JBrowse link
G Ptger1 prostaglandin E receptor 1 affects expression ISO Phosgene affects the expression of PTGER1 mRNA CTD PMID:16300373 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression ISO Phosgene affects the expression of PTGS1 mRNA CTD PMID:16300373 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP
ISO		 Phosgene results in increased expression of PTGS2 protein
ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Phosgene results in increased expression of PTGS2 protein]		 CTD PMID:21818760 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 affects expression ISO Phosgene affects the expression of PTK2 mRNA CTD PMID:16300373 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Pycard PYD and CARD domain containing increases expression EXP Phosgene results in increased expression of PYCARD mRNA; Phosgene results in increased expression of PYCARD protein CTD PMID:33012731 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rdh11 retinol dehydrogenase 11 affects expression ISO Phosgene affects the expression of RDH11 mRNA CTD PMID:16300373 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 affects expression ISO Phosgene affects the expression of RGS16 mRNA CTD PMID:16300373 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Rin1 Ras and Rab interactor 1 affects expression ISO Phosgene affects the expression of RIN1 mRNA CTD PMID:16300373 NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 affects expression ISO Phosgene affects the expression of RPS6KA2 mRNA CTD PMID:16300373 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739 		JBrowse link
G S100a14 S100 calcium binding protein A14 affects expression ISO Phosgene affects the expression of S100A14 mRNA CTD PMID:16300373 NCBI chr 2:176,008,395...176,010,423
Ensembl chr 2:176,008,395...176,010,423 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 affects expression ISO Phosgene affects the expression of SARS1 mRNA CTD PMID:16300373 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 affects expression ISO Phosgene affects the expression of SAT1 mRNA CTD PMID:16300373 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Sema3b semaphorin 3B affects expression ISO Phosgene affects the expression of SEMA3B mRNA CTD PMID:16300373 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919 		JBrowse link
G Serpina3n serpin family A member 3N affects expression ISO Phosgene affects the expression of SERPINA3N mRNA CTD PMID:16300373 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpine1 serpin family E member 1 affects expression ISO Phosgene affects the expression of SERPINE1 mRNA CTD PMID:16300373 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpine2 serpin family E member 2 affects expression ISO Phosgene affects the expression of SERPINE2 mRNA CTD PMID:16300373 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sftpb surfactant protein B multiple interactions ISO [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with Phosgene] results in increased expression of SFTPB mRNA CTD PMID:25870319 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression ISO Phosgene affects the expression of SHANK3 mRNA CTD PMID:16300373 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Sipa1 signal-induced proliferation-associated 1 affects expression ISO Phosgene affects the expression of SIPA1 mRNA CTD PMID:16300373 NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 affects expression ISO Phosgene affects the expression of SLC3A2 mRNA CTD PMID:16300373 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc7a10 solute carrier family 7 member 10 affects expression ISO Phosgene affects the expression of SLC7A10 mRNA CTD PMID:16300373 NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071 		JBrowse link
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 affects expression ISO Phosgene affects the expression of SMARCE1 mRNA CTD PMID:16300373 NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989 		JBrowse link
G Sod2 superoxide dismutase 2 affects expression ISO Phosgene affects the expression of SOD2 mRNA CTD PMID:16300373 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 affects expression ISO Phosgene affects the expression of SOD3 mRNA CTD PMID:16300373 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sort1 sortilin 1 affects expression ISO Phosgene affects the expression of SORT1 mRNA CTD PMID:16300373 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Sox18 SRY-box transcription factor 18 affects expression ISO Phosgene affects the expression of SOX18 mRNA CTD PMID:16300373 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
G Sox4 SRY-box transcription factor 4 affects expression ISO Phosgene affects the expression of SOX4 mRNA CTD PMID:16300373 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sphk1 sphingosine kinase 1 affects expression ISO Phosgene affects the expression of SPHK1 mRNA CTD PMID:16300373 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 affects expression ISO Phosgene affects the expression of SPOCK2 mRNA CTD PMID:16300373 NCBI chr20:28,037,334...28,064,272
Ensembl chr20:28,033,475...28,064,272 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 affects expression ISO Phosgene affects the expression of ST3GAL2 mRNA CTD PMID:16300373 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
G Stab1 stabilin 1 affects expression ISO Phosgene affects the expression of STAB1 mRNA CTD PMID:16300373 NCBI chr16:6,330,435...6,360,934
Ensembl chr16:6,330,444...6,360,923 		JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 affects expression ISO Phosgene affects the expression of STARD13 mRNA CTD PMID:16300373 NCBI chr12:566,282...959,372
Ensembl chr12:566,310...959,421 		JBrowse link
G Tbx2 T-box transcription factor 2 affects expression ISO Phosgene affects the expression of TBX2 mRNA CTD PMID:16300373 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
G Tek TEK receptor tyrosine kinase affects expression ISO Phosgene affects the expression of TEK mRNA CTD PMID:16300373 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Thbs1 thrombospondin 1 affects expression ISO Phosgene affects the expression of THBS1 mRNA CTD PMID:16300373 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 affects expression ISO Phosgene affects the expression of TIE1 mRNA CTD PMID:16300373 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Phosgene affects the expression of TIMP1 mRNA CTD PMID:16300373 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression		 ISO N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Phosgene results in decreased expression of TJP1 mRNA] CTD PMID:25870319 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP Phosgene results in increased expression of TNF protein
NLRP3 protein promotes the reaction [Phosgene results in increased expression of TNF protein]		 CTD PMID:33012731 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A affects expression ISO Phosgene affects the expression of TNFRSF12A mRNA CTD PMID:16300373 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tpra1 transmembrane protein adipocyte associated 1 affects expression ISO Phosgene affects the expression of TPRA1 mRNA CTD PMID:16300373 NCBI chr 4:121,364,093...121,375,275
Ensembl chr 4:121,364,091...121,375,269 		JBrowse link
G Tspo translocator protein affects expression ISO Phosgene affects the expression of TSPO mRNA CTD PMID:16300373 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Tuba1c tubulin, alpha 1C affects expression ISO Phosgene affects the expression of TUBA1C mRNA CTD PMID:16300373 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Txnl1 thioredoxin-like 1 affects expression ISO Phosgene affects the expression of TXNL1 mRNA CTD PMID:16300373 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266 		JBrowse link
G Txnrd1 thioredoxin reductase 1 affects expression ISO Phosgene affects the expression of TXNRD1 mRNA CTD PMID:16300373 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression		 ISO
EXP		 Phosgene results in decreased expression of VEGFA mRNA; Phosgene results in decreased expression of VEGFA protein
Phosgene results in increased expression of VEGFA mRNA alternative form		 CTD PMID:15256155 PMID:18645720 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wrnip1 WRN helicase interacting protein 1 affects expression ISO Phosgene affects the expression of WRNIP1 mRNA CTD PMID:16300373 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      chemical role 19507
        environmental contaminant 18882
          formaldehyde 3670
            phosgene 181
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbon oxoacid 18681
                                    carboxylic acid 18678
                                      carboacyl group 17728
                                        univalent carboacyl group 17728
                                          formyl group 9053
                                            aldehyde 9053
                                              formaldehyde 3670
                                                phosgene 181
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