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G |
Alb |
albumin |
multiple interactions affects binding |
ISO |
[ALB protein binds to Myristic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Myristic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Myristic Acid] which results in decreased reduction of Dithionitrobenzoic Acid |
CTD |
PMID:25451573 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Myristic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects binding |
ISO |
Myristic Acid binds to PPARA protein |
CTD |
PMID:10403814 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
Myristic Acid results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Dbi |
diazepam binding inhibitor |
affects binding |
ISO |
S-tetradecanoyl-coenzyme A binds to DBI protein |
CTD |
PMID:17044054 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
A2m |
alpha-2-macroglobulin |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of A2M mRNA |
CTD |
PMID:2440878 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]; eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]] |
CTD |
PMID:20438634 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions decreases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] |
CTD |
PMID:11331069 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
decreases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of ABCC1 protein Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC1 protein] |
CTD |
PMID:15517594 PMID:18473823 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein] |
CTD |
PMID:18473823 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ABCC4 mRNA |
CTD |
PMID:19142964 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ACACA mRNA |
CTD |
PMID:37055963 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Ace |
angiotensin I converting enzyme |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein] |
CTD |
PMID:11158990 PMID:15071347 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Aco1 |
aconitase 1 |
multiple interactions increases activity |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein] Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein] |
CTD |
PMID:10889193 |
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NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Actb |
actin, beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA |
CTD |
PMID:15477007 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Adam12 |
ADAM metallopeptidase domain 12 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM12 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
increases response to substance multiple interactions increases expression |
ISO |
ADAM17 results in increased susceptibility to Tetradecanoylphorbol Acetate [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein] ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein] |
CTD |
PMID:12147693 PMID:23774263 PMID:24632454 PMID:26298005 PMID:28703301 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adam8 |
ADAM metallopeptidase domain 8 |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM8 mRNA Tetradecanoylphorbol Acetate results in increased expression of ADAM8 mRNA |
CTD |
PMID:16979875 PMID:19945525 |
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NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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G |
Adm |
adrenomedullin |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of ADM mRNA |
CTD |
PMID:11470465 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Adora2a |
adenosine A2a receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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G |
Adora3 |
adenosine A3 receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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G |
Adra1a |
adrenoceptor alpha 1A |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ADRA1A mRNA |
CTD |
PMID:7900855 |
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NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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G |
Adra1d |
adrenoceptor alpha 1D |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ADRA1D mRNA |
CTD |
PMID:7900855 |
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NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
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G |
Adra2a |
adrenoceptor alpha 2A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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G |
Adrb2 |
adrenoceptor beta 2 |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of ADRB2 protein |
CTD |
PMID:14722251 |
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NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Afp |
alpha-fetoprotein |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP protein |
CTD |
PMID:16368122 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]] |
CTD |
PMID:23541064 |
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA |
CTD |
PMID:19840844 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions affects response to substance decreases expression increases expression affects localization |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of AHR mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and affects the localization of AHR protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SAA3 mRNA]]; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein] AHR protein affects the susceptibility to Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased expression of AHR protein [Tetradecanoylphorbol Acetate co-treated with Tetrachlorodibenzodioxin] results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein] Tetradecanoylphorbol Acetate results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate results in increased expression of AHR protein Tetradecanoylphorbol Acetate affects the localization of AHR protein |
CTD |
PMID:1313028 PMID:8390902 PMID:8396892 PMID:9415701 PMID:9706865 PMID:20423157 PMID:23291558 PMID:24481452 More...
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Ahrr |
aryl-hydrocarbon receptor repressor |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA Tetradecanoylphorbol Acetate results in increased expression of AHRR mRNA |
CTD |
PMID:11423533 |
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NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
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G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
multiple interactions decreases expression |
ISO |
[Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 protein |
CTD |
PMID:25463304 PMID:26198647 |
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NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of AKR1C2 mRNA [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of AKR1C21 mRNA |
CTD |
PMID:18353537 PMID:26198647 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of AKT1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein cyclosporin H inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:20172950 PMID:20438634 PMID:20660715 PMID:22465218 PMID:25590691 PMID:25866363 PMID:27432484 PMID:30590137 PMID:34144024 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alas1 |
5'-aminolevulinate synthase 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ALAS mRNA |
CTD |
PMID:15797241 |
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NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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G |
Alb |
albumin |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA] |
CTD |
PMID:24211529 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of ALOX5 protein; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein |
CTD |
PMID:10779545 PMID:11698504 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ANXA1 mRNA |
CTD |
PMID:19945525 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa10 |
annexin A10 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA10 mRNA |
CTD |
PMID:16979875 |
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NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ANXA2 protein |
CTD |
PMID:20045496 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Anxa3 |
annexin A3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
affects expression |
ISO |
Tetradecanoylphorbol Acetate affects the expression of APAF1 protein |
CTD |
PMID:11139146 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions |
ISO |
[ferric chloride co-treated with Tetradecanoylphorbol Acetate] affects the localization of APEX1 protein |
CTD |
PMID:12023366 |
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NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of APEX2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
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G |
Aplp2 |
amyloid beta precursor like protein 2 |
multiple interactions increases secretion |
ISO |
N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of APLP2 protein] |
CTD |
PMID:16279945 |
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NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA] [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] |
CTD |
PMID:20660715 PMID:22643241 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Arf1 |
ADP-ribosylation factor 1 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of ARF1 protein |
CTD |
PMID:10931844 |
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NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434
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G |
Arf6 |
ADP-ribosylation factor 6 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of ARF6 protein |
CTD |
PMID:10931844 PMID:16280360 |
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NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
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G |
Arhgap20 |
Rho GTPase activating protein 20 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ARHGAP20 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739
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G |
Arhgef9 |
Cdc42 guanine nucleotide exchange factor 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARHGEF9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513
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G |
Arl4c |
ADP ribosylation factor like GTPase 4C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARL4C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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G |
Arl6ip5 |
ADP-ribosylation factor like GTPase 6 interacting protein 5 |
multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Tretinoin results in increased expression of ARL6IP5 mRNA] Tetradecanoylphorbol Acetate results in increased expression of ARL6IP5 protein |
CTD |
PMID:16430862 PMID:16468075 |
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NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arpc2 |
actin related protein 2/3 complex, subunit 2 |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] |
CTD |
PMID:15477007 PMID:16027158 |
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NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
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G |
Art3 |
ADP-ribosyltransferase 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
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G |
Asf1a |
anti-silencing function 1A histone chaperone |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ASF1A mRNA |
CTD |
PMID:26198647 |
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NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ASS1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf5 |
activating transcription factor 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ATF5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ATP1B1 mRNA |
CTD |
PMID:11204457 |
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NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions decreases expression increases activity |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 protein Tetradecanoylphorbol Acetate results in increased activity of ATP2A2 protein |
CTD |
PMID:17003265 PMID:19244478 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp6v1c2 |
ATPase H+ transporting V1 subunit C2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
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G |
Atp7a |
ATPase copper transporting alpha |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein] which results in increased export of Copper; ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA] |
CTD |
PMID:19205902 |
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NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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G |
Atp7b |
ATPase copper transporting beta |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein |
CTD |
PMID:21189263 |
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NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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G |
Aurka |
aurora kinase A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of AURKA mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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G |
Bace1 |
beta-secretase 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] |
CTD |
PMID:23541064 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Bach1 |
BTB domain and CNC homolog 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of BACH1 mRNA |
CTD |
PMID:33268675 |
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NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAD protein |
CTD |
PMID:25446327 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
multiple interactions |
ISO |
BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA]; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] |
CTD |
PMID:20858459 |
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NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BAK1 protein |
CTD |
PMID:11139146 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
ISO EXP |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAX protein; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein] Tetradecanoylphorbol Acetate results in decreased expression of BAX protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of BAX protein] Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BAX protein] |
CTD |
PMID:15748703 PMID:19161993 PMID:22760862 PMID:25446327 PMID:32662567 PMID:36925031 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
ISO EXP |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2 mRNA; edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in decreased expression of BCL2 protein] Tetradecanoylphorbol Acetate results in decreased expression of BCL2 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in decreased expression of BCL2 protein] Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of BCL2 protein] |
CTD |
PMID:9295281 PMID:11139146 PMID:15538571 PMID:15748703 PMID:16979875 PMID:19161993 PMID:19631781 PMID:22760862 PMID:24073338 PMID:25446327 PMID:32662567 PMID:36075570 PMID:36925031 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions increases expression |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2A1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA] |
CTD |
PMID:15477007 PMID:16979875 PMID:20438634 |
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NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BCL2L1 protein [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2L1 mRNA |
CTD |
PMID:11139146 PMID:18958680 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BECN1 protein |
CTD |
PMID:25446327 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions increases expression |
ISO |
CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BGLAP protein] |
CTD |
PMID:37562720 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BHMT mRNA |
CTD |
PMID:16368122 |
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NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Bik |
BCL2-interacting killer |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BIK mRNA |
CTD |
PMID:26198647 |
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NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of BIRC2 protein |
CTD |
PMID:15187025 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions increases expression |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] |
CTD |
PMID:14527959 PMID:24849683 PMID:31068361 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BIRC5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
decreases response to substance |
ISO |
BMI1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:24571310 |
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NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BMP2 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA] |
CTD |
PMID:10910055 PMID:21331654 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bnip3l |
BCL2 interacting protein 3 like |
multiple interactions increases expression |
EXP |
Plicamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNA] |
CTD |
PMID:16291751 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
Brca1 |
BRCA1, DNA repair associated |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BRCA1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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G |
Bsg |
basigin |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein] Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA; Tetradecanoylphorbol Acetate results in increased expression of BSG protein |
CTD |
PMID:16860414 PMID:17055343 PMID:18647594 |
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NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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G |
Bst1 |
bone marrow stromal cell antigen 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180
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G |
Btg2 |
BTG anti-proliferation factor 2 |
multiple interactions increases expression |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Go 6976] results in increased expression of BTG2 mRNA Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of BTG2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of BTG2 mRNA |
CTD |
PMID:2005087 PMID:15302583 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BUB1B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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G |
C3h15orf48 |
similar to human chromosome 15 open reading frame 48 |
affects response to substance affects expression |
ISO |
NMES1 affects the susceptibility to Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the expression of NMES1 |
CTD |
PMID:16044405 |
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NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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G |
C4a |
complement C4A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
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G |
C4b |
complement C4B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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G |
C5ar1 |
complement C5a receptor 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of C5AR1 protein |
CTD |
PMID:18559098 |
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NCBI chr 1:76,948,622...76,959,826
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G |
Cacna1g |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CALR mRNA |
CTD |
PMID:19031421 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Camk1 |
calcium/calmodulin-dependent protein kinase I |
multiple interactions increases phosphorylation |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein] |
CTD |
PMID:20590612 |
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NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081
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G |
Camk2b |
calcium/calmodulin-dependent protein kinase II beta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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G |
Capn11 |
calpain 11 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN11 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
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G |
Capn6 |
calpain 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CAPN6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr X:107,380,774...107,405,489
Ensembl chr X:107,380,774...107,405,489
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G |
Capn9 |
calpain 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr19:52,549,448...52,586,413
Ensembl chr19:52,549,448...52,586,413
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G |
Car14 |
carbonic anhydrase 14 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CA14 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
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G |
Car3 |
carbonic anhydrase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CAR3 protein |
CTD |
PMID:20045496 |
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NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased cleavage of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA] |
CTD |
PMID:21515303 PMID:22322153 PMID:23430110 PMID:23535185 PMID:24158569 PMID:26091108 More...
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] |
CTD |
PMID:19631781 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of CASP3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased activity of CASP3 protein Tetradecanoylphorbol Acetate results in decreased expression of CASP3 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in increased activity of CASP3 protein] |
CTD |
PMID:11139146 PMID:12165276 PMID:14610070 PMID:15538571 PMID:17309078 PMID:19631781 PMID:24073338 PMID:25446327 PMID:32662567 PMID:36075570 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CASP8 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP8 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] |
CTD |
PMID:12165276 PMID:15477007 PMID:18958680 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP9 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of and results in increased cleavage of CASP9 protein Tetradecanoylphorbol Acetate results in decreased expression of CASP9 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein] |
CTD |
PMID:17309078 PMID:24073338 PMID:25446327 PMID:32662567 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions decreases activity decreases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CAT mRNA; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased oxidation of 1,2-diaminobenzene] [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of CAT protein; [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAT protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; CAT inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]; Tetradecanoylphorbol Acetate inhibits the reaction [Patulin results in decreased activity of CAT protein] |
CTD |
PMID:2126186 PMID:3030588 PMID:11243714 PMID:12065085 PMID:12504893 PMID:14997284 PMID:16091123 PMID:18958680 PMID:19095747 PMID:19161993 PMID:20691676 PMID:21964610 PMID:22036979 PMID:22760862 PMID:22981962 PMID:23399806 PMID:31351099 PMID:32662567 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cblif |
cobalamin binding intrinsic factor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CBLIF mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:208,605,983...208,620,231
Ensembl chr 1:208,605,983...208,620,344
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G |
Cbr1 |
carbonyl reductase 1 |
multiple interactions |
ISO |
CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein] |
CTD |
PMID:25818598 |
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NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCL1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL11 protein; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein] |
CTD |
PMID:17572062 PMID:17685462 PMID:21331654 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression increases secretion |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL2 protein; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CCL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein] 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein] Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein |
CTD |
PMID:16376386 PMID:17572062 PMID:17685462 PMID:19063610 PMID:19945525 PMID:20438634 PMID:21035309 PMID:30254419 PMID:30696844 PMID:31217279 PMID:31351099 PMID:31904401 PMID:36416909 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCL20 mRNA |
CTD |
PMID:19945525 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] |
CTD |
PMID:15477007 PMID:17572062 PMID:17685462 PMID:36416909 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL4 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL4 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein] Tetradecanoylphorbol Acetate results in increased expression of CCL4 protein decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL4 protein] |
CTD |
PMID:9122163 PMID:17572062 PMID:17685462 PMID:18958680 PMID:31351099 |
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL5 mRNA |
CTD |
PMID:17572062 PMID:17685462 PMID:31904401 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCN1 mRNA] |
CTD |
PMID:15117851 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna2 |
cyclin A2 |
multiple interactions decreases expression increases expression |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein] Tetradecanoylphorbol Acetate results in decreased expression of CCNA2 protein Tetradecanoylphorbol Acetate results in increased expression of CCNA2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein |
CTD |
PMID:12421932 PMID:15949478 PMID:19031421 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions increases expression |
ISO |
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA] |
CTD |
PMID:10866668 PMID:19000923 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCNB2 mRNA [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCNB2 mRNA |
CTD |
PMID:16979875 PMID:19031421 |
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NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression increases expression |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of CCND1 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of CCND1 protein] Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCND1 protein |
CTD |
PMID:15949478 PMID:16368122 PMID:18922899 PMID:20438634 PMID:21375462 PMID:24073338 PMID:26537528 PMID:32662567 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd3 |
cyclin D3 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein] |
CTD |
PMID:12421932 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions increases expression |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein] |
CTD |
PMID:12421932 PMID:24073338 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccng1 |
cyclin G1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd14 |
CD14 molecule |
multiple interactions increases expression |
ISO |
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein] Tetradecanoylphorbol Acetate results in increased expression of CD14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD14 protein |
CTD |
PMID:16430862 PMID:19135038 PMID:20089671 PMID:26036281 PMID:30218697 PMID:33268675 PMID:34506768 More...
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd200 |
Cd200 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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G |
Cd28 |
Cd28 molecule |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Magnesium Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of CD28 protein |
CTD |
PMID:8662792 PMID:11465111 |
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NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cd302 |
CD302 molecule |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CD302 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045
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G |
Cd34 |
CD34 molecule |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 mRNA; [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 protein Tetradecanoylphorbol Acetate results in increased expression of CD34 protein |
CTD |
PMID:18922899 |
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NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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G |
Cd36 |
CD36 molecule |
decreases expression multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of CD36 mRNA 2-chloro-5-nitrobenzanilide inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; [15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 mRNA; [Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [titanium dioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CD36 protein; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; Dibutyl Phthalate inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [[15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]] tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD36 protein |
CTD |
PMID:12664607 PMID:16407258 PMID:16484594 PMID:21315065 PMID:23386263 PMID:24746987 PMID:30218697 PMID:32649966 PMID:34506768 PMID:37055963 More...
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd3e |
CD3 epsilon subunit of T-cell receptor complex |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3E protein] |
CTD |
PMID:2824607 |
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NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
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G |
Cd3g |
CD3 gamma subunit of T-cell receptor complex |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3G protein] |
CTD |
PMID:2824607 |
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NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
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G |
Cd4 |
Cd4 molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:157,668,878...157,695,366
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G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD40 mRNA; Apigenin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; fisetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD40 protein]; Quercetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein] |
CTD |
PMID:16601352 PMID:16979875 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd40lg |
CD40 ligand |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD40LG protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG protein |
CTD |
PMID:11297035 PMID:22851303 |
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NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein; Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] |
CTD |
PMID:9929743 PMID:15477007 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd68 |
Cd68 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD68 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD68 protein |
CTD |
PMID:25128825 PMID:28720485 PMID:31011801 |
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NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cd69 |
Cd69 molecule |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD69 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD69 protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein] 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein |
CTD |
PMID:12749906 PMID:17962511 PMID:23134680 PMID:23941771 PMID:26343699 PMID:30171972 PMID:31068361 More...
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NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD80 protein |
CTD |
PMID:30218697 |
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NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
Cd83 |
CD83 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD83 mRNA |
CTD |
PMID:31068361 |
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NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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G |
Cd9 |
CD9 molecule |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD9 protein [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD9 mRNA [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA |
CTD |
PMID:10910098 PMID:16979875 PMID:19840844 |
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NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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G |
Cdc20 |
cell division cycle 20 |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDC20 mRNA Tetradecanoylphorbol Acetate results in increased expression of CDC20 mRNA |
CTD |
PMID:16979875 PMID:19031421 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc25b |
cell division cycle 25B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CDC25B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
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G |
Cdc25c |
cell division cycle 25C |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of CDC25C protein |
CTD |
PMID:21375462 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdc42 |
cell division cycle 42 |
multiple interactions |
EXP |
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]]; Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone] |
CTD |
PMID:2153673 |
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NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein] |
CTD |
PMID:25656647 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh17 |
cadherin 17 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
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G |
Cdh2 |
cadherin 2 |
multiple interactions increases expression |
ISO |
antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] |
CTD |
PMID:25656647 PMID:28108223 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdh5 |
cadherin 5 |
multiple interactions increases phosphorylation |
ISO |
HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] |
CTD |
PMID:24211779 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions increases expression decreases expression |
ISO |
corosolic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA] |
CTD |
PMID:10866668 PMID:32135139 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
increases activity decreases phosphorylation multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein Tetradecanoylphorbol Acetate results in decreased phosphorylation of CDK2 protein Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein] Tetradecanoylphorbol Acetate results in increased expression of CDK2 protein |
CTD |
PMID:12421932 PMID:15978937 PMID:24073338 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdk4 |
cyclin-dependent kinase 4 |
decreases expression increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CDK4 mRNA Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CDK4 protein |
CTD |
PMID:10866668 PMID:15978937 PMID:24073338 |
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NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdk6 |
cyclin-dependent kinase 6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CDK6 protein |
CTD |
PMID:24073338 |
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NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Atrazine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Tetradecanoylphorbol Acetate promotes the reaction [Atrazine results in increased expression of CDKN1A mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter] Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein |
CTD |
PMID:9348195 PMID:10910055 PMID:15735102 PMID:15976015 PMID:15978937 PMID:18223691 PMID:18958680 PMID:19945525 PMID:23715767 PMID:24211529 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein] Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in increased expression of CDKN1B protein] |
CTD |
PMID:12421932 PMID:26537528 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN1C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN2A mRNA [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA |
CTD |
PMID:16368122 PMID:18922899 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
multiple interactions |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN2B protein] |
CTD |
PMID:12421932 |
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NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN2C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of CEBPB protein] Tetradecanoylphorbol Acetate results in decreased expression of CEBPB mRNA |
CTD |
PMID:19282384 PMID:33268675 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cfh |
complement factor H |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CFH mRNA |
CTD |
PMID:31904401 |
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NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of CGA mRNA |
CTD |
PMID:21467749 |
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NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Chat |
choline O-acetyltransferase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CHAT mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Chek1 |
checkpoint kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CHEK1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chrnb1 |
cholinergic receptor nicotinic beta 1 subunit |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions increases activity increases phosphorylation increases expression |
ISO |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein] 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein; Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] |
CTD |
PMID:10820281 PMID:15498850 PMID:16474181 PMID:21035309 PMID:23899529 PMID:26220752 PMID:31351099 More...
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CKS2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr17:13,570,611...13,575,770
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G |
Cldn4 |
claudin 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CLDN4 mRNA |
CTD |
PMID:19945525 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Cln3 |
CLN3 lysosomal/endosomal transmembrane protein, battenin |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
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G |
Clta |
clathrin, light chain A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Cmah |
cytidine monophospho-N-acetylneuraminic acid hydroxylase |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMAHP mRNA |
CTD |
PMID:16979875 |
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NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
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G |
Cmklr1 |
chemerin chemokine-like receptor 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129
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G |
Cnn1 |
calponin 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CNN1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CNN1 protein |
CTD |
PMID:15380616 |
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NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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G |
Cntn6 |
contactin 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CNTN6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:137,354,886...137,751,712
Ensembl chr 4:137,355,367...137,751,119
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL11A1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of COL1A2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of COL1A2 mRNA [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA |
CTD |
PMID:16979875 PMID:18922899 PMID:19840844 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL2A1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col6a1 |
collagen type VI alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] |
CTD |
PMID:15477007 PMID:19840844 |
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NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Comt |
catechol-O-methyltransferase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA |
CTD |
PMID:15477007 |
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NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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G |
Coro1b |
coronin 1B |
multiple interactions affects response to substance increases phosphorylation |
EXP ISO |
Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CORO1B protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] CORO1B protein modified form affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:16027158 |
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NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
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G |
Cox6a1 |
cytochrome c oxidase subunit 6A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
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G |
Cox8a |
cytochrome c oxidase subunit 8A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:204,402,118...204,404,439
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases activity increases phosphorylation |
ISO |
GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein] Tetradecanoylphorbol Acetate results in increased activity of CREB1 protein [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of CREB1 protein modified form]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter] |
CTD |
PMID:10601319 PMID:18791200 PMID:19282384 PMID:20032081 PMID:21047949 PMID:31068361 PMID:35608139 More...
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter] |
CTD |
PMID:16474181 PMID:19282384 PMID:21047949 |
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NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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G |
Crlf2 |
cytokine receptor-like factor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA] |
CTD |
PMID:29462589 |
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NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642
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G |
Crp |
C-reactive protein |
multiple interactions |
EXP |
CRP protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] |
CTD |
PMID:9767445 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Crtam |
cytotoxic and regulatory T cell molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CRTAM mRNA |
CTD |
PMID:16979875 |
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NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343
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G |
Cry1 |
cryptochrome circadian regulator 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CRY1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CSF2 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF2 mRNA; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein] 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] |
CTD |
PMID:1376361 PMID:11752025 PMID:16979875 PMID:17051331 PMID:17572062 PMID:17685462 More...
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF3 mRNA |
CTD |
PMID:9122163 PMID:16979875 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctbp1 |
C-terminal binding protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] |
CTD |
PMID:24211779 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA |
CTD |
PMID:19840844 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsd |
cathepsin D |
decreases cleavage |
ISO |
Tetradecanoylphorbol Acetate results in decreased cleavage of CTSD protein |
CTD |
PMID:36070022 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsg |
cathepsin G |
increases secretion affects localization |
ISO |
Tetradecanoylphorbol Acetate results in increased secretion of CTSG protein Tetradecanoylphorbol Acetate affects the localization of CTSG protein |
CTD |
PMID:25980585 PMID:34144024 |
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NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
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G |
Ctsh |
cathepsin H |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CTSH mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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G |
Ctsl |
cathepsin L |
multiple interactions decreases cleavage |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA Tetradecanoylphorbol Acetate results in decreased cleavage of CTSL protein |
CTD |
PMID:19840844 PMID:36070022 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Cul5 |
cullin 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CX3CL1 mRNA |
CTD |
PMID:19850645 |
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NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA |
CTD |
PMID:9122163 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions decreases expression |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA] |
CTD |
PMID:22359662 PMID:23519560 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA |
CTD |
PMID:22643241 PMID:23519560 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
multiple interactions decreases expression |
ISO |
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA] |
CTD |
PMID:22359662 |
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NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein |
CTD |
PMID:20852150 PMID:26513295 PMID:31351099 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA] |
CTD |
PMID:9122163 PMID:20172950 PMID:22359662 PMID:26513295 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CXCL6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
multiple interactions decreases expression |
ISO |
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA] |
CTD |
PMID:22359662 |
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NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions increases expression |
ISO |
[Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR1 protein; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA] |
CTD |
PMID:15265017 PMID:21045076 |
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NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
multiple interactions |
ISO |
[Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR2 protein |
CTD |
PMID:15265017 |
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NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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G |
Cyba |
cytochrome b-245 alpha chain |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA] |
CTD |
PMID:11172467 PMID:20523355 PMID:21705328 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions increases expression increases activity |
ISO |
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNA] Tetradecanoylphorbol Acetate results in increased activity of CYBB protein diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein] |
CTD |
PMID:9794432 PMID:29183754 |
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein] |
CTD |
PMID:15748703 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CYP11A1 protein |
CTD |
PMID:18755854 PMID:18787026 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CYP11B2 mRNA |
CTD |
PMID:15666830 |
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NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases activity |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA] Tetradecanoylphorbol Acetate results in decreased activity of CYP19A1 protein |
CTD |
PMID:10338361 PMID:16357189 |
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NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions affects response to substance decreases expression increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 protein; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1A1 protein results in increased abundance of 2-Methoxyestradiol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] CYP1A1 protein affects the susceptibility to Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 protein; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [benzotriphenylene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]] Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 protein |
CTD |
PMID:1313028 PMID:1497680 PMID:8242868 PMID:8396892 PMID:9415701 PMID:9706865 PMID:11710520 PMID:11728381 PMID:18078826 PMID:18958680 PMID:22643241 PMID:24481452 More...
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer] Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:1313028 PMID:10620351 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions decreases expression |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:9706865 PMID:10037446 PMID:11728381 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] |
CTD |
PMID:20206692 |
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NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
ISO |
Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol] Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein |
CTD |
PMID:8531136 PMID:8798623 PMID:9143349 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:16368122 |
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NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions decreases activity decreases expression |
ISO EXP |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP7B1 mRNA Tetradecanoylphorbol Acetate results in decreased activity of CYP7B1 protein Tetradecanoylphorbol Acetate results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:12029625 PMID:16368122 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Dapk1 |
death associated protein kinase 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DAPK1 mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA |
CTD |
PMID:10910055 PMID:23519560 |
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NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Dapk2 |
death-associated protein kinase 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
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G |
Dct |
dopachrome tautomerase |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA]; trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT protein] |
CTD |
PMID:15892717 |
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NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
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G |
Defb5 |
defensin beta 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein] |
CTD |
PMID:28720485 |
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NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467
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G |
Dio3 |
iodothyronine deiodinase 3 |
increases activity multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein Hydrogen Peroxide promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein] |
CTD |
PMID:16935842 PMID:18420745 |
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NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
affects response to substance |
ISO |
DLK1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:18575777 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DMP1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DNAJB9 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:10652249 |
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NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dner |
delta/notch-like EGF repeat containing |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of DNER mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] |
CTD |
PMID:23775084 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock8 |
dedicator of cytokinesis 8 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474
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G |
Dpyd |
dihydropyrimidine dehydrogenase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DPYD mRNA |
CTD |
PMID:15705907 |
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NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions increases expression |
ISO |
[Fluticasone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DUSP1 mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA] |
CTD |
PMID:15860753 PMID:20858459 PMID:31068361 |
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NCBI chr10:16,680,478...16,683,275
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G |
Dusp13b |
dual specificity phosphatase 13B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DUSP13B mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,533,547...2,575,539
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G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DUSP2 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp22 |
dual specificity phosphatase 22 |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene] |
CTD |
PMID:32135139 |
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NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
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G |
Dusp4 |
dual specificity phosphatase 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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G |
E2f4 |
E2F transcription factor 4 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein] |
CTD |
PMID:20479004 |
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NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806
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G |
Eea1 |
early endosome antigen 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] |
CTD |
PMID:22683840 |
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NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EEF1A1 protein |
CTD |
PMID:20045496 |
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NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
multiple interactions |
ISO |
phorbol 13-acetate 12-myristate inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] and decreases phosphorylation of EEF2 protein in colon cancer cells |
RGD |
PMID:31227218 |
RGD:153298919 |
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of EFEMP1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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G |
Efna4 |
ephrin A4 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EFNA4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
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G |
Egf |
epidermal growth factor |
multiple interactions increases expression |
ISO EXP |
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein] bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; TAPI-2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein; Zinc inhibits the reaction [Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]] Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein] |
CTD |
PMID:6309801 PMID:12947092 PMID:19447859 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases expression increases phosphorylation |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA |
CTD |
PMID:6309801 PMID:10516208 PMID:19447859 PMID:20660715 PMID:25866363 PMID:26100520 PMID:26513295 More...
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein] Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of EGR1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter] |
CTD |
PMID:2005087 PMID:10693946 PMID:10739673 PMID:10779383 PMID:10910055 PMID:15920718 PMID:19945525 PMID:20479004 PMID:23715767 PMID:31068361 More...
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of EGR2 mRNA |
CTD |
PMID:15477007 PMID:31068361 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Egr3 |
early growth response 3 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] |
CTD |
PMID:16091474 |
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NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
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G |
Egr4 |
early growth response 4 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EGR4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF2AK2 protein |
CTD |
PMID:30218697 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EIF4A1 mRNA |
CTD |
PMID:31068361 |
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NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858
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G |
Eif4e |
eukaryotic translation initiation factor 4E |
multiple interactions increases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; CGP 57380 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein] |
CTD |
PMID:9545260 PMID:12781867 |
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NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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G |
Eif4e1b |
eukaryotic translation initiation factor 4E family member 1B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA |
CTD |
PMID:23519560 |
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NCBI chr17:9,831,338...9,856,250
Ensembl chr17:9,832,230...9,835,137
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:12781867 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein] |
CTD |
PMID:12781867 |
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NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
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G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EIF4G2 protein |
CTD |
PMID:18491231 |
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NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EIF5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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G |
Elk1 |
ETS transcription factor ELK1 |
increases activity increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of ELK1 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of ELK1 protein |
CTD |
PMID:18791200 PMID:21375462 |
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NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
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G |
Elmo1 |
engulfment and cell motility 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788
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G |
Eln |
elastin |
multiple interactions decreases expression |
EXP |
[Okadaic Acid co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ELN mRNA Tetradecanoylphorbol Acetate results in decreased expression of ELN mRNA |
CTD |
PMID:8997264 |
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NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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G |
Endog |
endonuclease G |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] affects the localization of ENDOG protein |
CTD |
PMID:17309078 |
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NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein] |
CTD |
PMID:24632381 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Ephb6 |
Eph receptor B6 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230
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G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein |
CTD |
PMID:24704207 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions increases expression |
ISO |
PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein] |
CTD |
PMID:20479004 |
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
increases cleavage multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein] |
CTD |
PMID:9685416 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Ereg |
epiregulin |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EREG protein |
CTD |
PMID:15066986 |
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NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions decreases expression increases expression |
ISO |
Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of ESR1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ESR1 protein [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 protein; Tetradecanoylphorbol Acetate promotes the reaction [Estradiol results in increased expression of ESR1 protein] |
CTD |
PMID:9706865 PMID:10633228 PMID:16368122 PMID:19340542 PMID:20559769 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions decreases expression increases expression |
ISO |
Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA] |
CTD |
PMID:10633228 PMID:20559769 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
[sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of EZH2 protein |
CTD |
PMID:35364107 |
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NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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G |
F11r |
F11 receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA |
CTD |
PMID:23519560 |
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NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
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G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [F2 protein results in increased uptake of Manganese] |
CTD |
PMID:2125206 |
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NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions increases expression |
ISO |
ochratoxin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of F3 protein |
CTD |
PMID:9974427 PMID:18289624 PMID:25569083 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 mRNA; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 protein |
CTD |
PMID:30218697 PMID:37055963 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA] |
CTD |
PMID:21331654 PMID:23519560 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein; Tamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA] |
CTD |
PMID:20529085 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fau |
FAU ubiquitin like and ribosomal protein S30 fusion |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
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G |
Fbln7 |
fibulin 7 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FBLN7 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983
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G |
Fen1 |
flap structure-specific endonuclease 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FEN1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
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G |
Fga |
fibrinogen alpha chain |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FGA mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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G |
Fgb |
fibrinogen beta chain |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FGB mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf1 |
fibroblast growth factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Fgf10 |
fibroblast growth factor 10 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
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G |
Fgf16 |
fibroblast growth factor 16 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FGF16 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:70,816,658...70,828,028
Ensembl chr X:70,817,433...70,878,717
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G |
Fgf18 |
fibroblast growth factor 18 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions increases secretion |
EXP ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter] Tetradecanoylphorbol Acetate results in increased secretion of FGF2 protein |
CTD |
PMID:10779383 PMID:11874475 PMID:15654655 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:15654655 PMID:23519560 |
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NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Fgg |
fibrinogen gamma chain |
increases expression |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of FGG mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA] |
CTD |
PMID:20858459 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
multiple interactions increases secretion increases expression |
ISO |
ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FLT1 protein] |
CTD |
PMID:19205902 PMID:22197494 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Flt3 |
Fms related receptor tyrosine kinase 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
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G |
Fmo5 |
flavin containing dimethylaniline monoxygenase 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FMO5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
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G |
Fn1 |
fibronectin 1 |
multiple interactions increases secretion increases expression |
ISO |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FN1 mRNA; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FN1 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein] |
CTD |
PMID:15086456 PMID:16979875 PMID:24211529 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions affects localization increases activity increases expression |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOS mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOS mRNA; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of FOS mRNA] Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOS protein |
CTD |
PMID:1932749 PMID:7564102 PMID:7963561 PMID:8386370 PMID:8631129 PMID:9067545 PMID:9122163 PMID:9242432 PMID:9270009 PMID:9417049 PMID:9580328 PMID:9650640 PMID:10381133 PMID:10484327 PMID:10620351 PMID:10693946 PMID:10739673 PMID:10910055 PMID:11687581 PMID:12782152 PMID:15477007 PMID:15705907 PMID:16116958 PMID:17360982 PMID:17693661 PMID:18551458 PMID:18755854 PMID:19225867 PMID:19282384 PMID:19375915 PMID:19716839 PMID:19945525 PMID:20152819 PMID:20590612 PMID:20599481 PMID:21047949 PMID:21354279 PMID:22561169 PMID:22634262 PMID:25656647 PMID:30133131 PMID:30590137 PMID:30696844 PMID:31068361 PMID:31904401 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOSB mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSB protein [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOSB mRNA |
CTD |
PMID:17148446 PMID:31068361 PMID:31904401 |
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NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOSL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein] Tetradecanoylphorbol Acetate results in increased expression of FOSL1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein |
CTD |
PMID:9122163 PMID:17148446 PMID:18755854 PMID:19000923 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FOSL2 mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] |
CTD |
PMID:15477007 PMID:16979875 PMID:17148446 |
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NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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G |
Foxo3 |
forkhead box O3 |
multiple interactions decreases phosphorylation increases activity |
ISO |
FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2] Tetradecanoylphorbol Acetate results in decreased phosphorylation of FOXO3 protein Tetradecanoylphorbol Acetate results in increased activity of FOXO3 protein |
CTD |
PMID:21705328 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Foxp3 |
forkhead box P3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOXP3 protein |
CTD |
PMID:27865421 |
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NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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G |
Frmd3 |
FERM domain containing 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FRMD3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
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G |
Fscn1 |
fascin actin-bundling protein 1 |
multiple interactions increases expression |
ISO |
FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein] Tetradecanoylphorbol Acetate results in increased expression of FSCN1 mRNA |
CTD |
PMID:22102721 |
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NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
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G |
Fshb |
follicle stimulating hormone subunit beta |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FSHB mRNA |
CTD |
PMID:21467749 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fstl1 |
follistatin-like 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
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G |
Fstl4 |
follistatin-like 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FSTL4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:36,911,422...37,344,545
Ensembl chr10:36,911,420...37,338,588
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G |
Fut4 |
fucosyltransferase 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FUT4 protein |
CTD |
PMID:26036281 |
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NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
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G |
Fxyd6 |
FXYD domain-containing ion transport regulator 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FXYD6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958
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G |
Fyb1 |
FYN binding protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions decreases expression |
ISO |
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein] |
CTD |
PMID:23399806 |
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NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gabra3 |
gamma-aminobutyric acid type A receptor subunit alpha 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA |
CTD |
PMID:23519560 |
|
NCBI chr X:150,244,745...150,501,566
Ensembl chr X:150,261,607...150,501,559
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of GABRA4 mRNA Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] |
CTD |
PMID:16091474 |
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NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GADD45A mRNA |
CTD |
PMID:10910055 |
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gas6 |
growth arrest specific 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GAS6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gast |
gastrin |
increases secretion |
EXP |
Tetradecanoylphorbol Acetate results in increased secretion of GAST protein |
CTD |
PMID:19208342 |
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NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions increases activity |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter] Tetradecanoylphorbol Acetate results in increased activity of GATA1 protein |
CTD |
PMID:14623254 |
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NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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G |
Gata2 |
GATA binding protein 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA tellimagrandin I promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA] |
CTD |
PMID:14757314 |
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NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Gata3 |
GATA binding protein 3 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA |
CTD |
PMID:22398747 |
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NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
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G |
Gata4 |
GATA binding protein 4 |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GATA4 protein |
CTD |
PMID:11583584 |
|
NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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G |
Gatd1 |
glutamine amidotransferase class 1 domain containing 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GATD1 mRNA |
CTD |
PMID:31904401 |
|
NCBI chr 1:196,504,533...196,512,561
Ensembl chr 1:196,504,833...196,512,551
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G |
Gba1 |
glucosylceramidase beta 1 |
multiple interactions |
ISO |
GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] |
CTD |
PMID:24951586 |
|
NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
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G |
Gbp3 |
guanylate binding protein 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Rosuvastatin Calcium] results in increased expression of GCLC mRNA Tetradecanoylphorbol Acetate results in increased expression of GCLC mRNA |
CTD |
PMID:17200146 PMID:18154958 PMID:26198647 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] |
CTD |
PMID:24632381 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GCNT3 mRNA |
CTD |
PMID:26198647 |
|
NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
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G |
Gdf10 |
growth differentiation factor 10 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GDF10 mRNA |
CTD |
PMID:16979875 |
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NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
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G |
Gdf11 |
growth differentiation factor 11 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
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G |
Gdf15 |
growth differentiation factor 15 |
multiple interactions increases expression |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] |
CTD |
PMID:23996089 PMID:30218697 |
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NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gfi1 |
growth factor independent 1 transcriptional repressor |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of GFI1 mRNA |
CTD |
PMID:16888099 |
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NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
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G |
Gfra2 |
GDNF family receptor alpha 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions increases expression increases phosphorylation affects localization decreases expression decreases localization |
ISO EXP |
Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein] [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] Tetradecanoylphorbol Acetate results in increased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein modified form 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in decreased activity of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein Tetradecanoylphorbol Acetate affects the localization of GJA1 protein Tetradecanoylphorbol Acetate results in decreased expression of GJA1 mRNA Tetradecanoylphorbol Acetate results in decreased localization of GJA1 protein Tetradecanoylphorbol Acetate results in decreased expression of GJA1 protein |
CTD |
PMID:7586169 PMID:7586191 PMID:8020150 PMID:8068183 PMID:8285856 PMID:8597533 PMID:9797139 PMID:10633228 PMID:10973802 PMID:11532878 PMID:11711124 PMID:15250540 PMID:15685554 PMID:19840844 PMID:20510257 PMID:23978459 PMID:30668803 PMID:35413382 PMID:36925031 More...
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gjb2 |
gap junction protein, beta 2 |
multiple interactions increases expression decreases expression |
ISO EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJB2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJB2 mRNA Tetradecanoylphorbol Acetate results in increased expression of GJB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJB2 protein Tetradecanoylphorbol Acetate results in decreased expression of GJB2 protein |
CTD |
PMID:7586191 PMID:8068183 PMID:8597533 |
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NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
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G |
Gjb5 |
gap junction protein, beta 5 |
multiple interactions decreases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJB5 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GJB5 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GJB5 protein |
CTD |
PMID:7586191 PMID:8597533 |
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NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
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G |
Glra1 |
glycine receptor, alpha 1 |
decreases activity |
EXP |
Tetradecanoylphorbol Acetate results in decreased activity of GLRA1 protein |
CTD |
PMID:7752562 |
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NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
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G |
Gnrhr |
gonadotropin releasing hormone receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GNRHR mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
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G |
Gp1ba |
glycoprotein Ib platelet subunit alpha |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein] |
CTD |
PMID:20523355 |
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NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPAT3 mRNA |
CTD |
PMID:26198647 |
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NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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G |
Gpc4 |
glypican 4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] |
CTD |
PMID:2523799 |
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NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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G |
Gpr3 |
G protein-coupled receptor 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPR3 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590
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G |
Gpr84 |
G protein-coupled receptor 84 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPR84 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPX1 protein |
CTD |
PMID:10432307 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of GPX4 protein Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of GPX4 protein] |
CTD |
PMID:10432307 PMID:35608139 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gria3 |
glutamate ionotropic receptor AMPA type subunit 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096
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G |
Grik5 |
glutamate ionotropic receptor kainate type subunit 5 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA |
CTD |
PMID:23519560 |
|
NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
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G |
Grn |
granulin precursor |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GRN mRNA |
CTD |
PMID:16873554 |
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NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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G |
Grp |
gastrin releasing peptide |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [GRP protein modified form results in increased chemical synthesis of Inositol Phosphates] |
CTD |
PMID:18313772 |
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NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
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G |
Grpr |
gastrin releasing peptide receptor |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GRPR protein |
CTD |
PMID:29669290 |
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NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein] |
CTD |
PMID:17993264 |
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NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:17993264 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases expression decreases activity increases activity |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of GSR protein; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP] |
CTD |
PMID:11243714 PMID:12504893 PMID:14997284 PMID:19161993 PMID:20691676 PMID:22036979 PMID:22760862 PMID:23399806 More...
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gsto1 |
glutathione S-transferase omega 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions decreases expression increases expression |
ISO |
beta-lapachone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Emodin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; sanguinarine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter] Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 protein [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA |
CTD |
PMID:14623254 PMID:15313406 PMID:15533597 PMID:19840844 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTT1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Gtf2h4 |
general transcription factor 2H subunit 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GTF2H4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
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G |
Gypa |
glycophorin A |
multiple interactions increases expression decreases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; chebulinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] |
CTD |
PMID:14769215 PMID:20523355 |
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NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
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G |
Gzmb |
granzyme B |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein Tetradecanoylphorbol Acetate results in increased expression of GZMB mRNA |
CTD |
PMID:20883105 PMID:30171972 |
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NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Hal |
histidine ammonia lyase |
multiple interactions |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of HAL protein |
CTD |
PMID:20691676 |
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NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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G |
Hars1 |
histidyl-tRNA synthetase 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions increases expression increases secretion |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of HBEGF mRNA [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] Tetradecanoylphorbol Acetate results in increased expression of HBEGF mRNA |
CTD |
PMID:10910055 PMID:16979875 PMID:20660715 PMID:28703301 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA |
CTD |
PMID:15477007 PMID:23519560 |
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NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
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G |
Hdac5 |
histone deacetylase 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein] [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased expression of HDAC5 protein]] |
CTD |
PMID:19124542 PMID:36075570 |
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NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
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G |
Hdac9 |
histone deacetylase 9 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HDAC9 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
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G |
Hdc |
histidine decarboxylase |
increases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of HDC protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein; atractylon inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; pyeongwee-san extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein] |
CTD |
PMID:10428506 PMID:27553716 |
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NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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G |
Hebp2 |
heme binding protein 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HEBP2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
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G |
Hells |
helicase, lymphoid specific |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HELLS mRNA |
CTD |
PMID:19000923 |
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NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
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G |
Hgf |
hepatocyte growth factor |
multiple interactions increases expression |
ISO |
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein] Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA; Tetradecanoylphorbol Acetate results in increased expression of HGF protein [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA |
CTD |
PMID:15802798 PMID:23519560 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hhip |
Hedgehog-interacting protein |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA |
CTD |
PMID:23519560 |
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NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Dithiothreitol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA] Tetradecanoylphorbol Acetate results in increased expression of HIF1A mRNA alternative form; Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form |
CTD |
PMID:11424089 PMID:12479793 PMID:14695184 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HMGCR mRNA |
CTD |
PMID:12044893 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:12044893 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HMOX1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]] HMOX1 enhancer affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA] |
CTD |
PMID:7538129 PMID:18078826 PMID:18958680 PMID:23288142 PMID:24632381 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
multiple interactions increases expression |
ISO |
Indomethacin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HPGD mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein] |
CTD |
PMID:11237475 PMID:15680906 |
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NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of HRAS mRNA; HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein] [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate co-treated with mezerein] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; [Benzo(a)pyrene co-treated with Tetradecanoylphorbol Acetate] affects the mutagenesis of HRAS gene; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of HRAS protein; [Zidovudine co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA] |
CTD |
PMID:3115617 PMID:9766437 PMID:11241758 PMID:11765016 PMID:17106253 PMID:18922899 PMID:22760862 PMID:24211779 More...
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hrh1 |
histamine receptor H 1 |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRH1 mRNA] |
CTD |
PMID:23333628 |
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NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
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G |
Hrh2 |
histamine receptor H 2 |
multiple interactions |
ISO |
HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] |
CTD |
PMID:19277450 |
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NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
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G |
Hs6st2 |
heparan sulfate 6-O-sulfotransferase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HS6ST2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr X:130,966,547...131,261,629
Ensembl chr X:130,968,385...131,261,492
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases activity increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased activity of HSD11B1 protein Tetradecanoylphorbol Acetate results in increased expression of HSD11B1 mRNA |
CTD |
PMID:16533503 |
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NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
multiple interactions |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of HSPA2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA2 mRNA |
CTD |
PMID:18958680 |
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NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein] |
CTD |
PMID:10652249 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
multiple interactions |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HSPA6 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA6 mRNA |
CTD |
PMID:18958680 PMID:24849683 |
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NCBI chr13:83,273,176...83,274,317
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA9 mRNA |
CTD |
PMID:18958680 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
Pentobarbital inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HSPB1 protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of HSPB1 protein [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HSPB1 mRNA |
CTD |
PMID:7541446 PMID:10839933 PMID:31904401 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hyi |
hydroxypyruvate isomerase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HYI mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:131,894,575...131,897,709
Ensembl chr 5:131,894,598...131,897,251
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G |
Ibsp |
integrin-binding sialoprotein |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IBSP mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ICAM1 protein; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein] |
CTD |
PMID:10484327 PMID:11164475 PMID:20920494 PMID:30218697 PMID:31351099 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Ier2 |
immediate early response 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IER2 mRNA |
CTD |
PMID:31068361 |
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NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
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G |
Ier3 |
immediate early response 3 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA Tetradecanoylphorbol Acetate results in increased expression of IER3 mRNA |
CTD |
PMID:19840844 PMID:19945525 PMID:31068361 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifi27l2a |
interferon, alpha-inducible protein 27 like 2A |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI27L2A mRNA |
CTD |
PMID:31904401 |
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NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
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G |
Ifi44 |
interferon-induced protein 44 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI44 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
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G |
Ifng |
interferon gamma |
multiple interactions increases expression increases secretion |
ISO EXP |
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [2,4-diaminotoluene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Azathioprine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [Decitabine results in increased expression of PLA2G2A protein]]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA] 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Estradiol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Resveratrol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA] |
CTD |
PMID:1371491 PMID:12411406 PMID:12755381 PMID:12812920 PMID:14623498 PMID:14994387 PMID:15358692 PMID:15379866 PMID:15588918 PMID:16154495 PMID:16374615 PMID:16716911 PMID:17051331 PMID:17475810 PMID:17572062 PMID:17685462 PMID:18541274 PMID:18953428 PMID:19277450 PMID:21569788 PMID:22077062 PMID:22398747 PMID:24603311 PMID:25073960 PMID:26343699 PMID:29594315 PMID:30171972 PMID:31351099 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IGF1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IGF1 mRNA; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:10365914 PMID:16368122 PMID:31904401 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions increases phosphorylation |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] |
CTD |
PMID:26513295 |
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NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions increases expression |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP3 mRNA Tetradecanoylphorbol Acetate results in increased expression of IGFBP3 mRNA |
CTD |
PMID:16368122 PMID:19945525 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP7 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions increases activity increases phosphorylation |
ISO |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein |
CTD |
PMID:16474181 PMID:20584749 PMID:23899529 PMID:26220752 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein] decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein] |
CTD |
PMID:12115659 PMID:31351099 |
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NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il10 |
interleukin 10 |
multiple interactions decreases expression increases expression increases secretion |
ISO EXP |
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; catechol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL10 protein]; quinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein] Tetradecanoylphorbol Acetate results in decreased expression of IL10 mRNA [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [Silicon Dioxide co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased secretion of IL10 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; Genistein affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA] |
CTD |
PMID:12884291 PMID:15502056 PMID:15588918 PMID:15614042 PMID:16374615 PMID:16716911 PMID:17051331 PMID:17572062 PMID:17685462 PMID:19277450 PMID:20423157 PMID:22398747 PMID:25128825 PMID:27865421 PMID:29777833 PMID:38380914 More...
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il11 |
interleukin 11 |
multiple interactions increases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA] |
CTD |
PMID:22138297 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
IL12A results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:22359662 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12B mRNA Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] |
CTD |
PMID:15614042 PMID:36416909 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb1 |
interleukin 12 receptor subunit beta 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12RB1 protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA] |
CTD |
PMID:11441113 PMID:21331654 |
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NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
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G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12RB2 protein [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL12RB2 mRNA |
CTD |
PMID:11441113 PMID:16979875 |
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NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
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G |
Il13 |
interleukin 13 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL13 mRNA [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA] [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]] |
CTD |
PMID:10428506 PMID:21331654 PMID:22398747 PMID:26091108 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA; biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Genistein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; hexaconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; T0901317 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; tetraconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; triflumizol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] [Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein |
CTD |
PMID:22289359 PMID:25583575 PMID:26513295 PMID:27783946 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il17ra |
interleukin 17 receptor A |
multiple interactions decreases response to substance |
ISO |
[IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; IL17RA results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:22359662 |
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NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
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G |
Il18r1 |
interleukin 18 receptor 1 |
multiple interactions |
ISO |
[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL18R1 protein |
CTD |
PMID:14994387 |
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NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
ISO |
5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; [sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein]; diacerein inhibits the reaction [[sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1A protein |
CTD |
PMID:7665919 PMID:8435107 PMID:8702551 PMID:9122163 PMID:11851881 PMID:21045076 PMID:35364107 More...
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1B mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Poly dA-dT] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL1B protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein] [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1B protein |
CTD |
PMID:9122163 PMID:9584910 PMID:10072544 PMID:12812920 PMID:14623498 PMID:16374615 PMID:16557482 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18958421 PMID:20423157 PMID:20709134 PMID:21035309 PMID:21515303 PMID:21807015 PMID:22322153 PMID:22359662 PMID:22981962 PMID:23253724 PMID:23399806 PMID:23430110 PMID:23535185 PMID:23680697 PMID:24131540 PMID:24158569 PMID:24964617 PMID:25446327 PMID:25818598 PMID:26091108 PMID:29458014 PMID:29508652 PMID:30254419 PMID:31351099 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r1 |
interleukin 1 receptor type 1 |
multiple interactions increases expression |
ISO |
SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA] |
CTD |
PMID:21045076 |
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NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions increases expression |
ISO |
SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA] |
CTD |
PMID:21045076 |
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NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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G |
Il1rap |
interleukin 1 receptor accessory protein |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAP mRNA |
CTD |
PMID:16979875 |
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NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
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G |
Il1rapl2 |
interleukin 1 receptor accessory protein-like 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAPL2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:100,961,509...102,271,753
Ensembl chr X:100,961,812...102,271,753
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL1RL1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions increases expression |
ISO |
NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein] |
CTD |
PMID:10072544 |
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NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
increases secretion multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [bis(tri-n-butyltin)oxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Sodium Dodecyl Sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Dronabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; KN 93 inhibits the reaction [Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein] [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dexamethasone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [diethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Formaldehyde co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Isoniazid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [isophorone diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mitomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pyrimethamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Warfarin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Alitretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Lenalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter]; norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; SB 203580 inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA] |
CTD |
PMID:1371491 PMID:7815356 PMID:8658534 PMID:8662742 PMID:9439728 PMID:9571986 PMID:9925799 PMID:11592964 PMID:11809870 PMID:12165276 PMID:12411406 PMID:12421932 PMID:12749906 PMID:12812920 PMID:15379866 PMID:15477007 PMID:15588918 PMID:16055081 PMID:16154495 PMID:16168555 PMID:16241859 PMID:16374615 PMID:16531003 PMID:17051331 PMID:17572062 PMID:17615583 PMID:17630204 PMID:17685462 PMID:18423386 PMID:19277450 PMID:19880376 PMID:21075198 PMID:21511917 PMID:21569788 PMID:22398747 PMID:22561169 PMID:23134680 PMID:23941771 PMID:24603311 PMID:25073960 PMID:25770929 PMID:26343699 PMID:29594315 PMID:29777833 PMID:34051231 More...
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il21 |
interleukin 21 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] |
CTD |
PMID:22077062 |
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NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
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G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions increases secretion increases expression |
ISO EXP |
[Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2RA mRNA; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein]; Sirolimus inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein]; Sirolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2RA protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein] [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2RA protein 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; tetrathiomolybdate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] |
CTD |
PMID:7815356 PMID:8586487 PMID:9766631 PMID:12421932 PMID:12749906 PMID:16979875 PMID:22398747 PMID:23134680 PMID:26343699 PMID:27865421 PMID:30171972 More...
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NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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G |
Il2rb |
interleukin 2 receptor subunit beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
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G |
Il3 |
interleukin 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein] [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL3 mRNA |
CTD |
PMID:1376361 PMID:16979875 |
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NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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G |
Il33 |
interleukin 33 |
multiple interactions increases expression |
ISO |
FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL33 mRNA] |
CTD |
PMID:35717073 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
multiple interactions increases expression increases secretion |
ISO EXP |
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL4 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; Leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein] Tetradecanoylphorbol Acetate results in increased expression of IL4 mRNA [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Toluene 2,4-Diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA] [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein] |
CTD |
PMID:1371491 PMID:8658534 PMID:9766631 PMID:10428506 PMID:12709020 PMID:12755381 PMID:12884291 PMID:15588918 PMID:16601352 PMID:16979875 PMID:17572062 PMID:17685462 PMID:18325701 PMID:19277450 PMID:21515303 PMID:22398747 PMID:25073960 PMID:26091108 PMID:29777833 More...
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
multiple interactions increases secretion increases expression |
ISO EXP |
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL5 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein] Tetradecanoylphorbol Acetate results in increased expression of IL5 mRNA deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein] |
CTD |
PMID:1371491 PMID:8658534 PMID:12884291 PMID:16116958 PMID:16374615 PMID:17475810 PMID:17572062 PMID:17685462 PMID:18325701 More...
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il5ra |
interleukin 5 receptor subunit alpha |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of IL5RA mRNA |
CTD |
PMID:8049355 |
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NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
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G |
Il6 |
interleukin 6 |
multiple interactions increases secretion increases expression |
ISO EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL6 protein 3'(R)-O-beta-D-glucopyranosyl-3',4'-dihydroxanthyletin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of IL6 protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with 2-Propanol] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Sodium Dodecyl Sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL6 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; levistolide A inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; tepoxalin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased secretion of IL6 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein] |
CTD |
PMID:7759567 PMID:9122163 PMID:10072544 PMID:10428506 PMID:12884291 PMID:16227999 PMID:16374615 PMID:16484594 PMID:17051331 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18434080 PMID:18958421 PMID:19118619 PMID:19416633 PMID:19665545 PMID:19910455 PMID:20043298 PMID:20423157 PMID:20438634 PMID:20709134 PMID:21515303 PMID:22322153 PMID:22398747 PMID:22643241 PMID:22981962 PMID:22986104 PMID:23399806 PMID:23535185 PMID:23835587 PMID:24131540 PMID:24951586 PMID:24964617 PMID:25128825 PMID:25818598 PMID:29777833 PMID:30254419 PMID:30496664 PMID:30524225 PMID:30696844 PMID:30919561 PMID:31351099 PMID:31904401 PMID:32662567 PMID:36075570 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6r |
interleukin 6 receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL6R mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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G |
Il9r |
interleukin 9 receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL9R mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990
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G |
Inhbc |
inhibin subunit beta C |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Glucose] results in increased secretion of INS1 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:2523799 PMID:10221768 PMID:17069794 PMID:30761839 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:19840844 PMID:23680697 |
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NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Irak3 |
interleukin-1 receptor-associated kinase 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IRAK3 mRNA [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IRAK3 mRNA |
CTD |
PMID:16979875 PMID:31904401 |
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NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
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G |
Ireb2 |
iron responsive element binding protein 2 |
increases activity multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein] |
CTD |
PMID:10889193 |
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NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
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G |
Irf4 |
interferon regulatory factor 4 |
multiple interactions decreases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of IRF4 mRNA |
CTD |
PMID:15477007 PMID:33268675 |
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NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
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G |
Irf8 |
interferon regulatory factor 8 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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G |
Isg15 |
ISG15 ubiquitin-like modifier |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ISG15 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
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G |
Itga2 |
integrin subunit alpha 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ITGA2 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA] |
CTD |
PMID:17669516 PMID:21331654 |
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NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
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G |
Itga2b |
integrin subunit alpha 2b |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] |
CTD |
PMID:10428506 PMID:20523355 |
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NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
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G |
Itga5 |
integrin subunit alpha 5 |
multiple interactions increases expression |
ISO |
Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA] |
CTD |
PMID:24211529 |
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NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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G |
Itga7 |
integrin subunit alpha 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450
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G |
Itgal |
integrin subunit alpha L |
multiple interactions affects localization |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGAL protein] |
CTD |
PMID:20883105 |
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NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
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G |
Itgam |
integrin subunit alpha M |
multiple interactions increases expression increases localization increases expression |
ISO EXP |
2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; [salvin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGAM protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA; dimemorfan inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein] Tetradecanoylphorbol Acetate results in increased expression of ITGAM mRNA; Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein] PMA increases expression of ITGAM protein on monocytes PMA increases expression of Itgam protein on neutrophils |
CTD RGD |
PMID:10739673 PMID:11504768 PMID:16430862 PMID:16617325 PMID:18500357 PMID:19135038 PMID:19428933 PMID:21331654 PMID:26330309 PMID:29458014 PMID:30218697 PMID:34506768 PMID:36269090 PMID:18617650 PMID:8102031 More...
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RGD:329901662, RGD:329901912 |
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgax |
integrin subunit alpha X |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGAX mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
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G |
Itgb2 |
integrin subunit beta 2 |
increases expression multiple interactions affects localization |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; crenatoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] |
CTD |
PMID:16393473 PMID:20883105 |
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NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; tellimagrandin I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] |
CTD |
PMID:10910098 PMID:14757314 PMID:14769215 PMID:20523355 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Itgb6 |
integrin subunit beta 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGB6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
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G |
Itgb8 |
integrin subunit beta 8 |
multiple interactions |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ITGB8 mRNA |
CTD |
PMID:24849683 |
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NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ITPR1 protein alternative form |
CTD |
PMID:24073338 |
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NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
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G |
Ivl |
involucrin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA] |
CTD |
PMID:10866668 PMID:17148446 |
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NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] |
CTD |
PMID:26091108 |
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NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases activity increases expression multiple interactions increases phosphorylation affects localization increases localization |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased activity of JUN protein Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein; Tetradecanoylphorbol Acetate results in increased expression of JUN protein modified form [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] Tetradecanoylphorbol Acetate results in increased localization of JUN protein Tetradecanoylphorbol Acetate results in increased expression of JUN; Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein; [JUN gene mutant form results in increased activity of JUN protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein; [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of JUN protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Thiopental inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein] |
CTD |
PMID:1730747 PMID:1932749 PMID:8219202 PMID:8386370 PMID:9067545 PMID:9122163 PMID:9242432 PMID:9580328 PMID:10381133 PMID:10484327 PMID:10620351 PMID:10693946 PMID:12169099 PMID:15263067 PMID:15477007 PMID:15705907 PMID:15944151 PMID:16116958 PMID:17148446 PMID:17360982 PMID:18551458 PMID:18628248 PMID:18755854 PMID:19000923 PMID:19225867 PMID:19282384 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20172950 PMID:20590612 PMID:20599481 PMID:21047949 PMID:21354279 PMID:22542552 PMID:22561169 PMID:23835587 PMID:25073960 PMID:25463304 PMID:25656647 PMID:26100520 PMID:26513295 PMID:27278863 PMID:28108223 PMID:30133131 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31068361 More...
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein] Tetradecanoylphorbol Acetate results in increased expression of JUNB; Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUNB protein Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of JUNB mRNA] |
CTD |
PMID:1932749 PMID:8631129 PMID:15666830 PMID:15920718 PMID:17148446 PMID:19000923 PMID:19945525 PMID:31068361 More...
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer] Tetradecanoylphorbol Acetate results in increased expression of JUND mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUND protein |
CTD |
PMID:1932749 PMID:10620351 PMID:11507057 PMID:17148446 PMID:18755854 |
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NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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G |
Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
decreases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased activity of KCND3 protein alternative form |
CTD |
PMID:11709419 |
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NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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G |
Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
decreases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased activity of KCNE1 protein |
CTD |
PMID:1655403 |
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NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
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G |
Kcnip2 |
potassium voltage-gated channel interacting protein 2 |
decreases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA] |
CTD |
PMID:16385079 |
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NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
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G |
Kcnj4 |
potassium inwardly-rectifying channel, subfamily J, member 4 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [KCNJ4 protein results in decreased susceptibility to Rotenone] |
CTD |
PMID:18619942 |
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NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
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G |
Kif20a |
kinesin family member 20A |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KIF20A mRNA |
CTD |
PMID:16979875 |
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NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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G |
Kif20b |
kinesin family member 20B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF20B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
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G |
Kif23 |
kinesin family member 23 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF23 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
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G |
Kif2c |
kinesin family member 2C |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF2C mRNA |
CTD |
PMID:19031421 |
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NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
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G |
Klf12 |
KLF transcription factor 12 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KLF12 mRNA |
CTD |
PMID:16979875 |
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NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
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G |
Klf4 |
KLF transcription factor 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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G |
Klf6 |
KLF transcription factor 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Kpnb1 |
karyopherin subunit beta 1 |
increases expression multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of KPNB1 protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] |
CTD |
PMID:16365892 PMID:17615583 |
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NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein] [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS protein |
CTD |
PMID:15263067 PMID:16368122 |
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NCBI chr 4:178,185,418...178,218,484
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Krt18 |
keratin 18 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNA |
CTD |
PMID:16368122 |
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NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
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G |
Krt8 |
keratin 8 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein |
CTD |
PMID:16368122 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Lama5 |
laminin subunit alpha 5 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LAMB1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc2 |
laminin subunit gamma 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
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G |
Lck |
LCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] |
CTD |
PMID:8662792 |
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NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
multiple interactions increases phosphorylation |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA; KT 5926 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of LCP1 protein] |
CTD |
PMID:14769871 PMID:15477007 |
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NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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G |
Ldlr |
low density lipoprotein receptor |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LDLR mRNA; Tetradecanoylphorbol Acetate results in increased expression of LDLR protein Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] |
CTD |
PMID:29499335 PMID:31068361 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lef1 |
lymphoid enhancer binding factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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G |
Lgals3 |
galectin 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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G |
Lgals8 |
galectin 8 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of LGALS8 mRNA; [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Vehicle Emissions] results in increased expression of LGALS8 mRNA |
CTD |
PMID:18353537 |
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NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
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G |
Lhb |
luteinizing hormone subunit beta |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA Tetrachlorodibenzodioxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP] |
CTD |
PMID:2153673 PMID:21467749 |
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NCBI chr&n |