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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,4-D
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Accession:CHEBI:28854 term browser browse the term
Definition:A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.
Synonyms:related_synonym: (2,4-Dichlorphenoxy)essigsaeure;   (2,4-dichlorophenoxy)acetic acid;   2,4-D acid;   2,4-Dichlorophenoxyacetate;   2,4-Dichlorophenoxyacetic acid;   2,4-Dichlorphenoxyessigsaeure;   Hedonal;   Trinoxol;   acide 2,4-dichloro phenoxyacetique
 alt_id: CHEBI:48791;   CHEBI:73176;   CHEBI:910
 xref: CAS:94-75-7;   Gmelin:51306;   HMDB:HMDB0041797
 xref_mesh: MESH:D015084
 xref: PPDB:4;   Pesticides:2\,4-d;   Reaxys:1214242;   kegg.compound:C03664;   lincs.smallmolecule:LSM-19988;   metacyc.compound:CPD-9009;   pdb-ccd:CFA;   pubmed:10794133;   pubmed:11165716;   pubmed:11423340;   pubmed:11566291;   pubmed:12231832;   pubmed:15198722;   pubmed:16785163;   pubmed:17568655;   pubmed:18969687;   pubmed:6362003;   wikipedia.en:2\,4-Dichlorophenoxyacetic_acid
 chemrof_formula: C8H6Cl2O3
 chemrof_inchi: InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)
 chemrof_smiles: O=C(O)COc1ccc(Cl)cc1Cl
 chemrof_inchikey: OVSKIKFHRZPJSS-UHFFFAOYSA-N
 cyclic_relationship: is_conjugate_acid_of CHEBI:19351


show annotations for term's descendants           Sort by:
2,4-D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
multiple interactions 		ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ABCB4 mRNA 		CTD PMID:9210621 PMID:37567420 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ACOT1 mRNA CTD PMID:37567420 NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749 		JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ADGRF4 mRNA CTD PMID:37567420 NCBI chr 9:25,769,265...25,800,438
Ensembl chr 9:25,769,265...25,800,438 		JBrowse link
G Alb albumin affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to ALB protein CTD PMID:9877224 PMID:11451446 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ALDH1L2 mRNA CTD PMID:37567420 NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398 		JBrowse link
G Aldh3b3 aldehyde dehydrogenase 3 family, member B3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALDH3B3 mRNA CTD PMID:37567420 NCBI chr 1:210,617,090...210,629,886
Ensembl chr 1:210,622,639...210,629,879 		JBrowse link
G Alpk3 alpha-kinase 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALPK3 mRNA CTD PMID:37567420 NCBI chr 1:144,423,690...144,471,534
Ensembl chr 1:144,423,726...144,490,309 		JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of AOC1 mRNA CTD PMID:37567420 NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions
decreases expression 		ISO [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APAF1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of APAF1 protein
2,4-Dichlorophenoxyacetic Acid results in decreased expression of APAF1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of APAF1 protein 		CTD PMID:33865415 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Ar androgen receptor multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Androgens binds to AR protein]; 2,4-Dichlorophenoxyacetic Acid promotes the reaction [Dihydrotestosterone results in increased localization of and results in increased activity of AR protein]
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of AR protein; [Sucrose co-treated with Dietary Fats co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of AR mRNA 		CTD PMID:16107550 PMID:37516258 PMID:37615203 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Aspg asparaginase multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ASPG mRNA CTD PMID:37567420 NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417 		JBrowse link
G Axin2 axin 2 multiple interactions
increases expression 		ISO [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of AXIN2 mRNA
2,4-Dichlorophenoxyacetic Acid results in increased expression of AXIN2 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of AXIN2 protein 		CTD PMID:34463001 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575 		JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression 		EXP
ISO 		lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein] 		CTD PMID:34464015 PMID:35099110 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CACNA1S mRNA CTD PMID:37567420 NCBI chr13:50,045,668...50,115,903
Ensembl chr13:50,045,668...50,115,903 		JBrowse link
G Casp1 caspase 1 decreases cleavage
multiple interactions
increases cleavage 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in decreased cleavage of CASP1 protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased cleavage of CASP1 protein] 		CTD PMID:34464015 PMID:35099110 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form
2,4-Dichlorophenoxyacetic Acid results in increased activity of and results in increased cleavage of CASP3 protein; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of CASP3 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP3 mRNA; Acetylcysteine inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; dorsomorphin inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP3 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]; PRKAA1 protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of CASP3 protein]
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein] 		CTD PMID:36085217 PMID:36214342 PMID:37516258 PMID:39921193 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases cleavage
multiple interactions 		EXP 2,4-Dichlorophenoxyacetic Acid results in increased cleavage of CASP7 protein
Acetylcysteine inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased cleavage of CASP7 protein]; dorsomorphin inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased cleavage of CASP7 protein]; PRKAA1 protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of CASP7 protein] 		CTD PMID:39921193 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions 		ISO
EXP 		2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] affects the reaction [Ethanol results in increased expression of CASP8 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP8 mRNA; Ethanol affects the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP8 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein] 		CTD PMID:36085217 PMID:36214342 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage 		EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of CASP9 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP9 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CASP9 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased cleavage of CASP9 protein 		CTD PMID:36085217 PMID:39921193 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions EXP
ISO 		[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in decreased activity of CAT protein; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in decreased activity of CAT protein]
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of CAT mRNA] 		CTD PMID:36085217 PMID:37516258 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccdc120 coiled-coil domain containing 120 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:17,437,219...17,443,716
Ensembl chr  X:17,425,624...17,444,717 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL11 protein CTD PMID:19467290 NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions 		ISO
EXP 		2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL2 protein
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] affects the reaction [Ethanol results in increased expression of CCL2 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CCL2 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CCL2 mRNA] 		CTD PMID:19467290 PMID:36085217 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL4 protein CTD PMID:19467290 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Cd40lg CD40 ligand multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD40LG mRNA CTD PMID:37567420 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cd5 Cd5 molecule multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD5 mRNA CTD PMID:37567420 NCBI chr 1:216,790,245...216,811,209
Ensembl chr 1:216,790,245...216,811,209 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression
multiple interactions 		ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CDK6 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CDK6 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CDK6 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CDK6 protein 		CTD PMID:33865415 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701 		JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CELSR3 mRNA CTD PMID:37567420 NCBI chr 8:118,409,136...118,438,593
Ensembl chr 8:118,409,136...118,436,847 		JBrowse link
G Cimap1c ciliary microtubule associated protein 1C multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CIMAP1C mRNA CTD PMID:37567420 NCBI chr 8:66,144,726...66,176,985
Ensembl chr 8:66,144,726...66,181,546 		JBrowse link
G Cldn1 claudin 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 protein CTD PMID:28699141 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529 		JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 9:67,441,962...67,453,180
Ensembl chr 9:67,441,952...67,451,187 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CNP protein CTD PMID:18460445 NCBI chr10:86,011,504...86,018,063
Ensembl chr10:86,011,495...86,018,063 		JBrowse link
G Cntnap2 contactin associated protein 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CNTNAP2 mRNA CTD PMID:37567420 NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:75,109,858...77,366,258 		JBrowse link
G Col6a5 collagen type VI alpha 5 chain multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A5 mRNA CTD PMID:37567420 NCBI chr 8:115,362,532...115,462,844
Ensembl chr 8:115,361,906...115,462,859 		JBrowse link
G Col6a6 collagen type VI alpha 6 chain multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A6 mRNA CTD PMID:37567420 NCBI chr 8:115,196,833...115,352,161
Ensembl chr 8:115,197,464...115,352,136 		JBrowse link
G Crat carnitine O-acetyltransferase increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of CRAT protein CTD PMID:1755024 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression
multiple interactions 		ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 protein
PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA] 		CTD PMID:29633193 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CREB3L3 mRNA CTD PMID:37567420 NCBI chr 7:9,273,320...9,281,755
Ensembl chr 7:9,273,338...9,281,778 		JBrowse link
G Cst6 cystatin E/M multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CST6 mRNA CTD PMID:37567420 NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:212,084,676...212,086,384 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression ISO 2,4-Dichlorophenoxyacetic Acid affects the expression of CYP17A1 mRNA CTD PMID:26838045 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A1 mRNA CTD PMID:10910964 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A2 mRNA CTD PMID:10910964 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1B1 mRNA CTD PMID:10910964 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CYP26B1 mRNA CTD PMID:37567420 NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CYP2E1 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of CYP2E1 mRNA] CTD PMID:36085217 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Dbh dopamine beta-hydroxylase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of DBH protein CTD PMID:16931444 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DBP mRNA CTD PMID:37567420 NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205 		JBrowse link
G Dclre1c DNA cross-link repair 1C increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr17:79,684,988...79,718,399
Ensembl chr17:79,678,698...79,718,734 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DDB2 mRNA CTD PMID:15878651 NCBI chr 3:97,640,923...97,667,617
Ensembl chr 3:97,640,579...97,664,066 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DDIT3 mRNA CTD PMID:34626751 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dicer1 dicer 1 ribonuclease III multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DICER1 mRNA] CTD PMID:37516258 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:129,396,014...129,457,252 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA] CTD PMID:37516258 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dok7 docking protein 7 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DOK7 mRNA CTD PMID:37567420 NCBI chr14:79,890,051...79,924,081
Ensembl chr14:79,891,367...79,932,252 		JBrowse link
G Drosha drosha ribonuclease III multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DROSHA mRNA] CTD PMID:37516258 NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:63,591,968...63,703,687 		JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of DUSP5 mRNA CTD PMID:37567420 NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417 		JBrowse link
G Ebln1l1 endogenous Bornavirus like nucleoprotein 1 like 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV8-24 mRNA CTD PMID:37567420 NCBI chr10:79,435,547...79,437,553 JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX2 protein CTD PMID:1755024 PMID:3032197 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein] 		CTD PMID:36214342 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976 		JBrowse link
G Fam163a family with sequence similarity 163, member A multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FAM163A mRNA CTD PMID:37567420 NCBI chr13:70,813,129...70,891,410
Ensembl chr13:70,813,134...70,891,316 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
increases response to substance 		ISO
EXP 		FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP3 protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein modified form]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CASP8 protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FADD protein]; FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FAS protein]
FAS protein results in increased susceptibility to 2,4-Dichlorophenoxyacetic Acid 		CTD PMID:36214342 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand increases expression
multiple interactions 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in increased expression of FASLG protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASL protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FASLG protein] 		CTD PMID:36214342 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fbxo48 F-box protein 48 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FBXO48 mRNA CTD PMID:37567420 NCBI chr14:95,582,493...95,583,950
Ensembl chr14:95,581,279...95,587,616 		JBrowse link
G Fendrr FOXF1 adjacent non-coding developmental regulatory RNA multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FENDRR mRNA CTD PMID:37567420 NCBI chr19:66,035,910...66,061,466
Ensembl chr19:66,036,856...66,044,268 		JBrowse link
G Ffar3 free fatty acid receptor 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FFAR3 mRNA CTD PMID:37567420 NCBI chr 1:95,232,804...95,234,144
Ensembl chr 1:95,232,336...95,234,354 		JBrowse link
G Fhad1 forkhead associated phosphopeptide binding domain 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FHAD1 mRNA CTD PMID:37567420 NCBI chr 5:159,474,111...159,593,455
Ensembl chr 5:159,474,158...159,593,367 		JBrowse link
G Flg filaggrin multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FLG mRNA CTD PMID:37567420 NCBI chr 2:181,583,801...181,596,464
Ensembl chr 2:181,583,808...181,595,968 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases expression 		ISO PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 protein 		CTD PMID:29633193 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr 1:105,072,858...105,074,705
Ensembl chr  X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915 		JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GALNT16 mRNA CTD PMID:37567420 NCBI chr 6:105,900,987...105,982,039
Ensembl chr 6:105,901,153...105,991,350 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GALNT2 mRNA CTD PMID:37567420 NCBI chr19:69,110,657...69,222,237
Ensembl chr19:69,110,657...69,222,237 		JBrowse link
G Gcsam germinal center-associated, signaling and motility multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GCSAM mRNA CTD PMID:37567420 NCBI chr11:68,658,350...68,669,598
Ensembl chr11:68,660,438...68,669,584 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of GFAP mRNA CTD PMID:22954530 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685 		JBrowse link
G Gli2 GLI family zinc finger 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GLI2 mRNA CTD PMID:37567420 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418 		JBrowse link
G Gna15 G protein subunit alpha 15 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GNA15 mRNA CTD PMID:37567420 NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,835,357...8,856,268 		JBrowse link
G Golt1a golgi transport 1A multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GOLT1A mRNA CTD PMID:37567420 NCBI chr13:47,312,412...47,325,176
Ensembl chr13:47,322,002...47,325,175 		JBrowse link
G Gp5 glycoprotein V (platelet) multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GP5 mRNA CTD PMID:37567420 NCBI chr11:83,948,507...83,952,362
Ensembl chr11:83,948,507...83,952,367 		JBrowse link
G Gp6 glycoprotein 6 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GP6 mRNA CTD PMID:37567420 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374 		JBrowse link
G Gpr151 G protein-coupled receptor 151 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GPR151 mRNA CTD PMID:37567420 NCBI chr18:34,819,878...34,821,272
Ensembl chr18:34,819,878...34,821,272 		JBrowse link
G Gpr171 G protein-coupled receptor 171 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GPR171 mRNA CTD PMID:37567420 NCBI chr 2:145,510,305...145,515,392
Ensembl chr 2:145,505,549...145,515,592 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of GPT protein]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of GPT protein; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of GPT protein] CTD PMID:36085217 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity ISO 2,4-Dichlorophenoxyacetic Acid results in decreased activity of GPX1 protein CTD PMID:35099110 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of GSR mRNA] CTD PMID:37516258 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gucy2e guanylate cyclase 2E multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GUCY2E mRNA CTD PMID:37567420 NCBI chr10:54,453,753...54,478,639
Ensembl chr10:54,457,844...54,472,898 		JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HAMP mRNA CTD PMID:37567420 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HAPLN1 mRNA CTD PMID:37567420 NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:22,366,967...22,429,098 		JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of HCRT mRNA CTD PMID:37567420 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:86,189,775...86,191,524 		JBrowse link
G Hhipl1 HHIP-like 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HHIPL1 mRNA CTD PMID:37567420 NCBI chr 6:132,984,028...133,008,248
Ensembl chr 6:132,984,032...133,006,947 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCR CTD PMID:26838045 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCS1 CTD PMID:26838045 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HMOX1 mRNA CTD PMID:37567420 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of HSF2BP mRNA CTD PMID:37567420 NCBI chr20:10,035,263...10,121,262
Ensembl chr20:10,035,263...10,121,826 		JBrowse link
G Ifng interferon gamma increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igfn1 immunoglobulin-like and fibronectin type III domain containing 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGFN1 mRNA CTD PMID:37567420 NCBI chr13:49,947,330...49,979,203
Ensembl chr13:49,947,330...49,989,601 		JBrowse link
G Igkvl-ps13 immunoglobulin kappa variable like, pseudogene 13 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of IGKV1-133 mRNA CTD PMID:37567420 NCBI chr 4:98,298,232...98,299,135 JBrowse link
G Il10 interleukin 10 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of IL10 mRNA] CTD PMID:37516258 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IL12B mRNA CTD PMID:37567420 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein] 		CTD PMID:34464015 PMID:35099110 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]
[aminomethylphosphonic acid (AMPA) co-treated with 2,4-Dichlorophenoxyacetic Acid metabolite co-treated with Ethylenethiourea co-treated with desethylatrazine] results in decreased expression of IL1B protein 		CTD PMID:34464015 PMID:35099110 PMID:37236337 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of IL1RL1 mRNA CTD PMID:15878651 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il2 interleukin 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il4 interleukin 4 increases expression
increases secretion 		ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL4 protein
2,4-Dichlorophenoxyacetic Acid results in increased secretion of IL4 protein 		CTD PMID:19467290 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL5 protein CTD PMID:19467290 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions 		ISO
EXP 		2,4-Dichlorophenoxyacetic Acid results in increased expression of IL6 protein
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of IL6 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL6 protein] 		CTD PMID:19467290 PMID:34464015 PMID:35099110 PMID:37516258 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inhbb inhibin subunit beta B decreases secretion
multiple interactions 		ISO 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein
FAS protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased secretion of INHBB protein] 		CTD PMID:36214342 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:39921193 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ISLR2 mRNA CTD PMID:37567420 NCBI chr 8:67,504,042...67,512,125
Ensembl chr 8:67,504,037...67,513,708 		JBrowse link
G Ism2 isthmin 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ISM2 mRNA CTD PMID:37567420 NCBI chr 6:112,652,772...112,675,098
Ensembl chr 6:112,657,122...112,675,295 		JBrowse link
G Itgb1 integrin subunit beta 1 increases expression
multiple interactions 		ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of ITGB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of ITGB1 protein
[Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ITGB1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ITGB1 protein 		CTD PMID:33865415 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of KCNIP2 mRNA CTD PMID:37567420 NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:254,590,175...254,613,898 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KCNMA1 mRNA CTD PMID:37567420 NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117 		JBrowse link
G Krt20 keratin 20 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KRT20 mRNA CTD PMID:37567420 NCBI chr10:84,880,952...84,890,285
Ensembl chr10:84,880,952...84,890,285 		JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of LAX1 mRNA CTD PMID:37567420 NCBI chr13:47,686,840...47,697,396
Ensembl chr13:47,686,849...47,697,460 		JBrowse link
G Lca5l lebercilin LCA5 like multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LCA5L mRNA CTD PMID:37567420 NCBI chr11:48,930,127...48,964,613
Ensembl chr11:48,930,127...48,964,551 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA protein CTD PMID:23538319 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Lin7b lin-7 homolog B, crumbs cell polarity complex component multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LIN7B mRNA CTD PMID:37567420 NCBI chr 1:104,983,368...104,986,795
Ensembl chr 1:104,982,771...104,986,078 		JBrowse link
G Llcfc1 LLLL and CFNLAS motif containing 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LLCFC1 mRNA CTD PMID:37567420 NCBI chr 4:71,532,854...71,534,229
Ensembl chr 4:71,532,901...71,534,225 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LRCH4 mRNA CTD PMID:37567420 NCBI chr12:24,694,364...24,709,354
Ensembl chr12:24,694,370...24,706,412 		JBrowse link
G Lrrtm1 leucine rich repeat transmembrane neuronal 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LRRTM1 mRNA CTD PMID:37567420 NCBI chr 4:111,246,213...111,295,638
Ensembl chr 4:111,235,054...111,276,818 		JBrowse link
G Maob monoamine oxidase B multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of MAOB mRNA CTD PMID:37567420 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases expression
multiple interactions
affects localization 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]
2,4-Dichlorophenoxyacetic Acid affects the localization of MAP1LC3B protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid affects the localization of MAP1LC3B protein]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA] 		CTD PMID:34464015 PMID:35099110 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP 2,4-Dichlorophenoxyacetic Acid results in increased phosphorylation of MAPK1 protein CTD PMID:39921193 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP 2,4-Dichlorophenoxyacetic Acid results in increased phosphorylation of MAPK3 protein CTD PMID:39921193 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation EXP 2,4-Dichlorophenoxyacetic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:39921193 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mbp myelin basic protein decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of MBP protein CTD PMID:18460445 NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of MKI67 mRNA] CTD PMID:37516258 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of MTHFD2 mRNA CTD PMID:37567420 NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO 2,4-Dichlorophenoxyacetic Acid results in decreased methylation of MYC promoter CTD PMID:11857776 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nanp N-acetylneuraminic acid phosphatase multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NANP mRNA CTD PMID:37567420 NCBI chr 3:160,289,269...160,302,001
Ensembl chr 3:160,288,830...160,302,002 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression 		ISO [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NFKB1 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NFKB1 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of NFKB1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of NFKB1 protein 		CTD PMID:33865415 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions 		EXP
ISO 		2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 protein]
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of BECN1 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in decreased expression of MAP1LC3B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein] 		CTD PMID:34464015 PMID:35099110 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nobox NOBOX oogenesis homeobox multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NOBOX mRNA CTD PMID:37567420 NCBI chr 4:73,128,926...73,134,431
Ensembl chr 4:73,127,925...73,134,630 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NRG1 mRNA CTD PMID:37567420 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Nt5c1a 5'-nucleotidase, cytosolic IA multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NT5C1A mRNA CTD PMID:37567420 NCBI chr 5:140,758,219...140,782,706
Ensembl chr 5:140,757,729...140,778,968 		JBrowse link
G Ntm neurotrimin multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NTM mRNA CTD PMID:37567420 NCBI chr 8:35,634,929...36,625,081
Ensembl chr 8:35,635,640...36,624,807 		JBrowse link
G Nxph4 neurexophilin 4 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NXPH4 mRNA CTD PMID:37567420 NCBI chr 7:65,253,043...65,261,864
Ensembl chr 7:65,252,904...65,261,864 		JBrowse link
G Ocln occludin decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of OCLN mRNA CTD PMID:28699141 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide decreases secretion EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of OXT protein CTD PMID:20122984 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:138,235,754...138,236,594 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage 		EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of PARP1 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PARP1 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PARP1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased cleavage of PARP1 protein 		CTD PMID:36085217 PMID:39921193 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcdh10 protocadherin 10 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PCDH10 mRNA CTD PMID:37567420 NCBI chr 2:130,553,432...130,619,591
Ensembl chr 2:130,553,425...130,613,407 		JBrowse link
G Pcdhga8 protocadherin gamma subfamily A, 8 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PCDHGA8 mRNA CTD PMID:37567420 NCBI chr18:29,805,113...29,919,095 JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
multiple interactions
decreases expression 		ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of PCNA mRNA
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate] promotes the reaction [[lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of PCNA protein]; [2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate] results in decreased expression of PCNA protein; [2,4-Dichlorophenoxyacetic Acid co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of PCNA protein
2,4-Dichlorophenoxyacetic Acid results in decreased expression of PCNA protein 		CTD PMID:15878651 PMID:37615203 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PCSK2 mRNA CTD PMID:37567420 NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849 		JBrowse link
G Penk proenkephalin multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PENK mRNA CTD PMID:37567420 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705 		JBrowse link
G Per3 period circadian regulator 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PER3 mRNA CTD PMID:37567420 NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999 		JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM protein CTD PMID:23538319 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PHGDH mRNA CTD PMID:37567420 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Plxdc1 plexin domain containing 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PLXDC1 mRNA CTD PMID:37567420 NCBI chr10:83,418,837...83,478,451
Ensembl chr10:83,418,837...83,478,755 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PNPLA3 mRNA CTD PMID:37567420 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:117,173,516...117,194,594 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance ISO PPARA protein results in increased susceptibility to 2,4-Dichlorophenoxyacetic Acid CTD PMID:26838045 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions
increases expression 		ISO PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of CREB1 mRNA]; PPARB protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of FOXO1 mRNA]
2,4-Dichlorophenoxyacetic Acid results in increased expression of PPARB mRNA 		CTD PMID:29633193 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP PRKAA1 protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of CASP3 protein]; PRKAA1 protein affects the reaction [2,4-Dichlorophenoxyacetic Acid results in increased activity of CASP7 protein] CTD PMID:39921193 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prl prolactin decreases secretion EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of PRL protein CTD PMID:20122984 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Prok1 prokineticin 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PROK1 mRNA CTD PMID:37567420 NCBI chr 2:197,538,747...197,547,550
Ensembl chr 2:197,537,068...197,547,550 		JBrowse link
G Prr33 proline rich 33 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PRR33 mRNA CTD PMID:37567420 NCBI chr 1:207,074,382...207,080,233
Ensembl chr 1:207,045,684...207,078,423 		JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PTGER3 mRNA CTD PMID:15878651 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:249,264,985...249,409,846 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of PTGS2 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PTGS2 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of PTGS2 mRNA] CTD PMID:36085217 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pycard PYD and CARD domain containing increases expression
multiple interactions 		EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of PYCARD protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of PYCARD protein] 		CTD PMID:34464015 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419 		JBrowse link
G R3hdml R3H domain containing-like multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of R3HDML mRNA CTD PMID:37567420 NCBI chr 3:172,590,815...172,601,584
Ensembl chr 3:172,590,815...172,602,009 		JBrowse link
G Rasl12 RAS-like, family 12 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of RASL12 mRNA CTD PMID:37567420 NCBI chr 8:74,813,000...74,827,041
Ensembl chr 8:74,813,000...74,827,897 		JBrowse link
G Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RBPJL mRNA CTD PMID:37567420 NCBI chr 3:173,553,389...173,565,869
Ensembl chr 3:173,553,498...173,565,869 		JBrowse link
G Rd3 RD3 regulator of GUCY2D multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of RD3 mRNA CTD PMID:37567420 NCBI chr13:106,060,657...106,097,063
Ensembl chr13:106,084,171...106,093,540 		JBrowse link
G Recql4 RecQ like helicase 4 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RECQL4 mRNA CTD PMID:37567420 NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:110,304,094...110,311,258 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of RELA mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of RELA mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of RELA mRNA] CTD PMID:36085217 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rmi2 RecQ mediated genome instability 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of RMI2 mRNA CTD PMID:37567420 NCBI chr10:5,336,269...5,344,202
Ensembl chr10:5,338,060...5,344,235 		JBrowse link
G Rptn repetin multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of RPTN mRNA CTD PMID:37567420 NCBI chr 2:181,743,463...181,750,101
Ensembl chr 2:181,745,307...181,749,364 		JBrowse link
G Sbsn suprabasin multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SBSN mRNA CTD PMID:37567420 NCBI chr 1:95,106,390...95,133,448
Ensembl chr 1:95,120,927...95,134,220 		JBrowse link
G Scarna17 small Cajal body-specific RNA 17 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of SCARNA17 mRNA CTD PMID:37567420 NCBI chr18:70,619,801...70,619,941 JBrowse link
G Sik1 salt-inducible kinase 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SIK1 mRNA CTD PMID:37567420 NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698 		JBrowse link
G Slc16a3 solute carrier family 16 member 3 decreases expression
increases expression 		EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC16A3 mRNA
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC16A3 mRNA 		CTD PMID:23538319 NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903 		JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Potassium promotes the reaction [SLC22A12 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid] CTD PMID:15284287 NCBI chr 1:213,274,266...213,282,793
Ensembl chr 1:213,274,275...213,281,380 		JBrowse link
G Slc22a19 solute carrier family 22, member 19 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [SLC22A19 protein results in increased uptake of ochratoxin A] CTD PMID:15068970 NCBI chr 1:214,339,594...214,394,681
Ensembl chr 1:214,339,599...214,394,681 		JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:212,686,691...212,703,163
Ensembl chr 1:212,686,691...212,703,163 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SLC22A3 mRNA CTD PMID:37567420 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake
multiple interactions 		EXP
ISO 		SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid
p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid] 		CTD PMID:16857889 PMID:17255469 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SLC26A3 mRNA CTD PMID:37567420 NCBI chr 6:53,751,415...53,792,300
Ensembl chr 6:53,751,415...53,792,294 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression
increases expression 		EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC2A3 mRNA 		CTD PMID:23538319 NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity
multiple interactions 		ISO 2,4-Dichlorophenoxyacetic Acid results in decreased activity of SOD1 protein
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of SOD1 mRNA] 		CTD PMID:35099110 PMID:37516258 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of SPP1 mRNA CTD PMID:37567420 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of SPTA1 mRNA CTD PMID:37567420 NCBI chr13:88,735,833...88,811,697
Ensembl chr13:88,735,833...88,811,697 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression 		EXP
ISO 		lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein]
2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein
lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 mRNA]; NLRP3 protein promotes the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of SQSTM1 protein] 		CTD PMID:34464015 PMID:35099110 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of SRXN1 mRNA CTD PMID:34626751 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765 		JBrowse link
G Stx19 syntaxin 19 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of STX19 mRNA CTD PMID:37567420 NCBI chr11:13,619,436...13,624,634
Ensembl chr11:13,593,134...13,629,410 		JBrowse link
G Tbx15 T-box transcription factor 15 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TBX15 mRNA CTD PMID:37567420 NCBI chr 2:189,265,373...189,376,466
Ensembl chr 2:189,265,373...189,376,466 		JBrowse link
G Tdrd9 tudor domain containing 9 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TDRD9 mRNA CTD PMID:37567420 NCBI chr 6:136,850,797...136,966,225
Ensembl chr 6:136,850,812...136,966,225 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] affects the reaction [Ethanol results in increased expression of TGFB1 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TGFB1 mRNA; Ethanol affects the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TGFB1 mRNA] CTD PMID:36085217 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of TH protein CTD PMID:16931444 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 protein CTD PMID:28699141 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tlcd2 TLC domain containing 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TLCD2 mRNA CTD PMID:37567420 NCBI chr10:60,809,391...60,812,617
Ensembl chr10:60,809,391...60,811,599 		JBrowse link
G Tmem232 transmembrane protein 232 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TMEM232 mRNA CTD PMID:37567420 NCBI chr 9:112,334,569...112,562,627
Ensembl chr 9:112,334,569...112,580,069 		JBrowse link
G Tmem52 transmembrane protein 52 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TMEM52 mRNA CTD PMID:37567420 NCBI chr 5:171,330,948...171,332,704
Ensembl chr 5:171,330,966...171,332,704 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions 		ISO
EXP 		2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF; 2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF protein
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of TNF mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TNF mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TNF mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF protein]
2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of TNF mRNA]; lycium barbarum polysaccharide inhibits the reaction [2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF protein] 		CTD PMID:20728597 PMID:34464015 PMID:35099110 PMID:36085217 PMID:37516258 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfsf14 TNF superfamily member 14 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TNFSF14 mRNA CTD PMID:37567420 NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,155,270...2,160,191 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		ISO
EXP 		2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of TP53 mRNA]; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 mRNA; [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 protein
[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol results in increased expression of TP53 mRNA]; [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TP53 mRNA; Ethanol promotes the reaction [[2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] which results in increased expression of TP53 mRNA] 		CTD PMID:33865415 PMID:36085217 PMID:37516258 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tp73 tumor protein p73 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP73 mRNA CTD PMID:37567420 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552 		JBrowse link
G Tpsb2 tryptase beta 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TPSB2 mRNA CTD PMID:37567420 NCBI chr10:14,886,310...14,888,102
Ensembl chr10:14,886,360...14,888,100 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of TSKU mRNA CTD PMID:37567420 NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of UGT1A1 mRNA CTD PMID:37567420 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of UGT1A2 mRNA CTD PMID:37567420 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Upp2 uridine phosphorylase 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of UPP2 mRNA CTD PMID:37567420 NCBI chr 3:63,681,671...63,726,194
Ensembl chr 3:63,681,826...63,726,191 		JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of USP19 mRNA CTD PMID:15878651 NCBI chr 8:118,069,227...118,080,283
Ensembl chr 8:118,069,240...118,080,300 		JBrowse link
G Vash2 vasohibin 2 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of VASH2 mRNA CTD PMID:37567420 NCBI chr13:105,060,857...105,092,325
Ensembl chr13:105,060,857...105,092,275 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of VWA1 mRNA CTD PMID:37567420 NCBI chr 5:171,659,694...171,664,880
Ensembl chr 5:171,659,698...171,664,880 		JBrowse link
G Zfand4 zinc finger AN1-type containing 4 multiple interactions ISO [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ZFAND4 mRNA CTD PMID:37567420 NCBI chr 4:150,999,821...151,071,942
Ensembl chr 4:150,999,836...151,072,055 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        agrochemical 16228
          2,4-D 209
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                carbocyclic compound 18739
                                  benzenoid aromatic compound 17899
                                    benzenes 17656
                                      chlorobenzenes 15281
                                        chlorophenoxyacetic acid 312
                                          2,4-D 209
paths to the root