Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(aminomethyl)phosphonic acid
go back to main search page
Accession:CHEBI:28812 term browser browse the term
Definition:A member of the class of phosphonic acids that is phosphonic acid substituted by an aminomethyl group. It is a metabolite of the herbicide glyphosate.
Synonyms:related_synonym: 1-Aminomethylphosphonic acid;   AMPA;   Formula=CH6NO3P;   InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5);   InChIKey=MGRVRXRGTBOSHW-UHFFFAOYSA-N;   SMILES=NCP(O)(O)=O
 alt_id: CHEBI:22515;   CHEBI:2358
 xref: CAS:1066-51-9;   DrugBank:DB02057;   Gmelin:793599;   KEGG:C11033
 xref_mesh: MESH:C036423
 xref: MetaCyc:CPD0-1074;   PMID:15291487;   PMID:15950343;   Reaxys:1701219;   UM-BBD_compID:c0136;   Wikipedia:Aminomethylphosphonic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:133674


show annotations for term's descendants           Sort by:
(aminomethyl)phosphonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in decreased expression of BIRC2 protein CTD PMID:26006246 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in decreased expression of BIRC3 protein CTD PMID:26006246 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO 1-aminomethylphosphonic acid results in increased activity of CASP3 protein
[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of and results in increased activity of CASP3 protein		 CTD PMID:23983455 PMID:26006246 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:26006246 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression		 ISO [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased expression of CASP9 protein
1-aminomethylphosphonic acid results in increased expression of CASP9 protein		 CTD PMID:23983455 PMID:26006246 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases expression		 ISO [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in decreased expression of CCND3 protein
1-aminomethylphosphonic acid results in decreased expression of CCND3 protein		 CTD PMID:23983455 PMID:26006246 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO 1-aminomethylphosphonic acid results in increased expression of CDKN1A protein
[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased expression of CDKN1A protein		 CTD PMID:23983455 PMID:26006246 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO 1-aminomethylphosphonic acid results in increased cleavage of PARP1 protein
[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of PARP1 protein		 CTD PMID:23983455 PMID:26006246 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO 1-aminomethylphosphonic acid results in increased expression of TP53 protein CTD PMID:23983455 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pesticide 18067
          fungicide 14030
            phosphonic acid 4465
              (aminomethyl)phosphonic acid 9
                (acetamidomethyl)phosphonic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      chalcogen 19569
                        oxygen atom 19541
                          oxygen molecular entity 19541
                            hydroxides 19347
                              oxoacid 18782
                                pnictogen oxoacid 14977
                                  phosphorus oxoacid 14577
                                    phosphonic acid 4465
                                      (aminomethyl)phosphonic acid 9
                                        (acetamidomethyl)phosphonic acid 0
paths to the root