|
G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions
|
ISO
|
4-cymene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with beta-pinene co-treated with gamma-terpinene co-treated with cuminol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] results in increased activity of AHR protein
|
CTD |
PMID:29191726 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
4-cymene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:29191726 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
|
G
|
Ache
|
acetylcholinesterase
|
multiple interactions decreases activity
|
EXP
|
[propiconazole co-treated with carvacrol] results in decreased activity of ACHE protein carvacrol results in decreased activity of ACHE protein
|
CTD |
PMID:29852196 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
|
|
G
|
Acta2
|
actin alpha 2, smooth muscle
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]; carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]]
|
CTD |
PMID:29071762 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
|
|
G
|
Ager
|
advanced glycosylation end product-specific receptor
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of AGER mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
|
|
G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions increases activity
|
ISO
|
[4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; carvacrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] carvacrol results in increased activity of AHR protein
|
CTD |
PMID:29191726 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
G
|
Alb
|
albumin
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in decreased expression of ALB protein]
|
CTD |
PMID:34155936 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
|
|
G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of APAF1 mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Ethanol results in increased expression of BAX protein]; carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of BAX mRNA]
|
CTD |
PMID:37499997 PMID:39105374 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Ethanol results in decreased expression of BCL2 protein]; carvacrol inhibits the reaction [Mercuric Chloride results in decreased expression of BCL2 mRNA]
|
CTD |
PMID:37499997 PMID:39105374 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
G
|
Becn1
|
beclin 1
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of BECN1 mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
|
G
|
Casp3
|
caspase 3
|
increases activity multiple interactions
|
ISO EXP
|
carvacrol results in increased activity of CASP3 protein carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 mRNA]; carvacrol inhibits the reaction [Poloxamer results in increased expression of CASP3 protein]; carvacrol inhibits the reaction [propiconazole results in increased expression of CASP3 protein]; carvacrol inhibits the reaction [Simvastatin promotes the reaction [Poloxamer results in increased expression of CASP3 protein]]; carvacrol inhibits the reaction [Thioacetamide results in increased expression of CASP3 protein]
|
CTD |
PMID:23146755 PMID:29071762 PMID:29852196 PMID:34155936 PMID:39105374 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of CASP9 mRNA]
|
CTD |
PMID:39105374 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
EXP ISO
|
carvacrol inhibits the reaction [Ethanol results in decreased expression of CAT protein]; carvacrol inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; carvacrol inhibits the reaction [Poloxamer results in decreased activity of CAT protein]; carvacrol inhibits the reaction [propiconazole results in decreased activity of CAT protein]; carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased activity of CAT protein]] carvacrol inhibits the reaction [Diethylhexyl Phthalate results in increased activity of CAT protein] carvacrol inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]
|
CTD |
PMID:29019276 PMID:29071762 PMID:29852196 PMID:35521929 PMID:37499997 PMID:39105374 More...
|
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
G
|
Ckm
|
creatine kinase, M-type
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Poloxamer results in increased secretion of CKM protein]; carvacrol inhibits the reaction [Simvastatin results in increased secretion of CKM protein]
|
CTD |
PMID:29071762 |
|
NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
|
|
G
|
Cryz
|
crystallin zeta
|
multiple interactions
|
ISO
|
carvacrol inhibits the reaction [Benzo(a)pyrene results in decreased activity of CRYZ protein]
|
CTD |
PMID:29019276 |
|
NCBI chr 2:246,211,707...246,239,472
Ensembl chr 2:246,211,156...246,239,470
|
|
G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
multiple interactions
|
ISO
|
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased expression of CXCL1 protein]]; carvacrol inhibits the reaction [irinotecan results in increased expression of CXCL1 protein]
|
CTD |
PMID:27838229 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
increases expression multiple interactions
|
ISO
|
carvacrol results in increased expression of CYP1A1 mRNA carvacrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:29191726 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
G
|
Egfr
|
epidermal growth factor receptor
|
increases phosphorylation multiple interactions
|
ISO
|
carvacrol results in increased phosphorylation of EGFR protein KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:32535744 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased expression of ENPP2 protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
carvacrol affects the reaction [Streptozocin results in decreased expression of FSHB protein]
|
CTD |
PMID:32153207 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
|
|
G
|
Fshr
|
follicle stimulating hormone receptor
|
multiple interactions
|
EXP
|
carvacrol affects the reaction [Streptozocin results in decreased expression of FSHR mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of FSHR protein]
|
CTD |
PMID:32153207 |
|
NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288
|
|
G
|
Gfap
|
glial fibrillary acidic protein
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [propiconazole results in increased expression of GFAP protein]
|
CTD |
PMID:29852196 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
|
|
G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased activity of GPT protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
|
|
G
|
Gpx1
|
glutathione peroxidase 1
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Ethanol results in decreased expression of GPX1 protein]
|
CTD |
PMID:37499997 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
|
|
G
|
Gpx4
|
glutathione peroxidase 4
|
affects binding
|
ISO
|
carvacrol binds to GPX4 protein
|
CTD |
PMID:37499997 |
|
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
|
|
G
|
Htr3a
|
5-hydroxytryptamine receptor 3A
|
increases activity
|
ISO
|
carvacrol results in increased activity of HTR3A protein
|
CTD |
PMID:26456648 |
|
NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO EXP
|
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased expression of IL1B protein]]; carvacrol inhibits the reaction [irinotecan results in increased expression of IL1B protein] carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of IL1B mRNA]; carvacrol inhibits the reaction [Thioacetamide results in increased expression of IL1B protein] carvacrol inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]
|
CTD |
PMID:26801986 PMID:27838229 PMID:34155936 PMID:39105374 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of IL6 mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
G
|
Ins1
|
insulin 1
|
multiple interactions
|
EXP
|
carvacrol affects the reaction [Streptozocin results in decreased expression of INS1 protein]
|
CTD |
PMID:32153207 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
|
|
G
|
Jak2
|
Janus kinase 2
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of JAK2 mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
|
|
G
|
Lep
|
leptin
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Poloxamer results in increased secretion of LEP protein]
|
CTD |
PMID:29071762 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions
|
EXP
|
carvacrol affects the reaction [Streptozocin results in decreased expression of LHB protein]
|
CTD |
PMID:32153207 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
G
|
Lhcgr
|
luteinizing hormone/choriogonadotropin receptor
|
multiple interactions
|
EXP
|
carvacrol affects the reaction [Streptozocin results in decreased expression of LHCGR mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of LHCGR protein]
|
CTD |
PMID:32153207 |
|
NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061
|
|
G
|
Map1lc3a
|
microtubule-associated protein 1 light chain 3 alpha
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of MAP1LC3A mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
|
|
G
|
Map1lc3b
|
microtubule-associated protein 1 light chain 3 beta
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of MAP1LC3B mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
|
|
G
|
Mb
|
myoglobin
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Poloxamer results in increased secretion of MB protein]
|
CTD |
PMID:29071762 |
|
NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958
|
|
G
|
Mmp3
|
matrix metallopeptidase 3
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased expression of MMP3 protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased expression of MMP9 protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
ISO
|
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased activity of MPO protein]]; carvacrol inhibits the reaction [irinotecan results in increased activity of MPO protein]
|
CTD |
PMID:27838229 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions
|
ISO EXP
|
carvacrol inhibits the reaction [irinotecan results in increased expression of NFKB1 protein] carvacrol inhibits the reaction [Ethanol results in increased expression of NFKB1 protein]; carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of NFKB1 mRNA]
|
CTD |
PMID:27838229 PMID:37499997 PMID:39105374 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in decreased expression of NFKBIA mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
G
|
Nlrp3
|
NLR family, pyrin domain containing 3
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of NLRP3 mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO EXP
|
carvacrol inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein] carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of NOS2 mRNA]; carvacrol inhibits the reaction [Thioacetamide results in increased expression of NOS2 protein]
|
CTD |
PMID:29019276 PMID:34155936 PMID:39105374 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
G
|
Nox1
|
NADPH oxidase 1
|
multiple interactions affects binding
|
EXP ISO
|
carvacrol inhibits the reaction [Ethanol results in increased expression of NOX1 protein] carvacrol binds to NOX1 protein
|
CTD |
PMID:37499997 |
|
NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520
|
|
G
|
Nox4
|
NADPH oxidase 4
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Ethanol results in increased expression of NOX4 protein]
|
CTD |
PMID:37499997 |
|
NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483
|
|
G
|
Nr5a1
|
nuclear receptor subfamily 5, group A, member 1
|
multiple interactions
|
EXP
|
carvacrol affects the reaction [Streptozocin results in decreased expression of NR5A1 mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of NR5A1 protein]
|
CTD |
PMID:32153207 |
|
NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
|
|
G
|
Pik3ca
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
multiple interactions increases phosphorylation
|
ISO
|
Erlotinib Hydrochloride inhibits the reaction [carvacrol results in increased phosphorylation of PIK3CA protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of PIK3CA protein]
|
CTD |
PMID:32535744 |
|
NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions
|
ISO EXP
|
carvacrol inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 protein]; carvacrol inhibits the reaction [Irinotecan results in increased expression of PTGS2 protein] carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]; carvacrol inhibits the reaction [propiconazole results in increased expression of PTGS2 protein]
|
CTD |
PMID:27838229 PMID:29019276 PMID:29852196 PMID:39105374 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions increases phosphorylation
|
ISO
|
Erlotinib Hydrochloride inhibits the reaction [carvacrol results in increased phosphorylation of RELA protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of RELA protein]
|
CTD |
PMID:32535744 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
G
|
Tgfa
|
transforming growth factor alpha
|
increases secretion multiple interactions
|
ISO
|
carvacrol results in increased secretion of TGFA protein KN 93 inhibits the reaction [carvacrol results in increased secretion of TGFA protein]
|
CTD |
PMID:32535744 |
|
NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO EXP
|
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased expression of TNF protein]]; carvacrol inhibits the reaction [irinotecan results in increased expression of TNF protein] carvacrol inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA] carvacrol inhibits the reaction [Ethanol results in increased expression of TNF protein]; carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]
|
CTD |
PMID:26801986 PMID:27838229 PMID:37499997 PMID:39105374 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Mercuric Chloride results in increased expression of TP53 mRNA]
|
CTD |
PMID:39105374 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
G
|
Trpa1
|
transient receptor potential cation channel, subfamily A, member 1
|
increases activity
|
EXP ISO
|
carvacrol results in increased activity of TRPA1 protein
|
CTD |
PMID:16617338 PMID:22935519 |
|
NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325
|
|
G
|
Trpv3
|
transient receptor potential cation channel, subfamily V, member 3
|
increases activity affects response to substance multiple interactions increases response to substance
|
ISO EXP
|
carvacrol results in increased activity of TRPV3 protein TRPV3 protein affects the susceptibility to carvacrol TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of EGFR protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of PIK3CA protein]; TRPV3 protein affects the reaction [carvacrol results in increased phosphorylation of RELA protein] TRPV3 protein results in increased susceptibility to carvacrol [carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium; [carvacrol results in increased activity of TRPV3 protein] which results in increased transport of Calcium; carvacrol binds to and results in increased activity of TRPV3 protein; Ruthenium Red inhibits the reaction [[carvacrol binds to and results in increased activity of TRPV3 protein] which results in increased transport of Calcium]
|
CTD |
PMID:16617338 PMID:20086034 PMID:29658714 PMID:32535744 |
|
NCBI chr10:58,382,054...58,413,657
Ensembl chr10:58,382,054...58,411,800
|
|
G
|
Txn1
|
thioredoxin 1
|
multiple interactions
|
EXP
|
carvacrol inhibits the reaction [Thioacetamide results in increased expression of TXN protein]
|
CTD |
PMID:34155936 |
|
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
|
|
G
|
Xdh
|
xanthine dehydrogenase
|
multiple interactions
|
ISO
|
carvacrol inhibits the reaction [Benzo(a)pyrene results in increased activity of XDH protein]
|
CTD |
PMID:29019276 |
|
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
|
|
|
G
|
Ar
|
androgen receptor
|
multiple interactions
|
ISO
|
Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein]
|
CTD |
PMID:31393563 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
|
|
G
|
Ctsd
|
cathepsin D
|
multiple interactions increases expression
|
ISO
|
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA]
|
CTD |
PMID:31393563 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
|
|
G
|
Cyp4f6
|
cytochrome P450, family 4, subfamily f, polypeptide 6
|
multiple interactions
|
ISO
|
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]
|
CTD |
PMID:31393563 |
|
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
|
|
G
|
Esr1
|
estrogen receptor 1
|
increases activity
|
ISO
|
Tea Tree Oil results in increased activity of ESR1 protein
|
CTD |
PMID:31393563 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
G
|
Greb1
|
growth regulating estrogen receptor binding 1
|
multiple interactions increases expression
|
ISO
|
Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA]
|
CTD |
PMID:31393563 |
|
NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
|
|
G
|
Pgr
|
progesterone receptor
|
increases expression multiple interactions
|
ISO
|
Tea Tree Oil results in increased expression of PGR mRNA Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]
|
CTD |
PMID:31393563 |
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
|
|
G
|
Sec14l2
|
SEC14-like lipid binding 2
|
multiple interactions
|
ISO
|
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]
|
CTD |
PMID:31393563 |
|
NCBI chr14:78,973,805...78,998,480
Ensembl chr14:83,197,387...83,217,317
|
|
G
|
Ugt2b34l1
|
UDP glucuronosyltransferase 2 family, polypeptide B34 like 1
|
multiple interactions
|
ISO
|
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]
|
CTD |
PMID:31393563 |
|
NCBI chr14:21,500,948...21,524,095
Ensembl chr14:21,501,091...21,522,265
|
|
|
G
|
Acp5
|
acid phosphatase 5, tartrate resistant
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of ACP5 mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of ACP5 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
|
|
G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions increases activity
|
ISO
|
[4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] results in increased activity of AHR protein; Thymol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] Thymol results in increased activity of AHR protein
|
CTD |
PMID:29191726 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
affects localization
|
ISO
|
Thymol affects the localization of AIFM1 protein
|
CTD |
PMID:21640085 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression multiple interactions
|
ISO EXP
|
Thymol results in increased expression of BAX protein Thymol results in increased expression of BAX mRNA Thymol inhibits the reaction [imidacloprid results in increased expression of BAX mRNA]
|
CTD |
PMID:21640085 PMID:34171690 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression multiple interactions
|
ISO EXP
|
Thymol results in decreased expression of BCL2 protein Thymol inhibits the reaction [imidacloprid results in decreased expression of BCL2 mRNA]
|
CTD |
PMID:21640085 PMID:34171690 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]
|
CTD |
PMID:26996544 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
G
|
Car2
|
carbonic anhydrase 2
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
G
|
Casp3
|
caspase 3
|
increases activity multiple interactions
|
ISO EXP
|
Thymol results in increased activity of CASP3 protein Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 mRNA]; Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 protein]
|
CTD |
PMID:21640085 PMID:34171690 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
G
|
Casp8
|
caspase 8
|
increases activity multiple interactions
|
ISO EXP
|
Thymol results in increased activity of CASP8 protein Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]
|
CTD |
PMID:21640085 PMID:26996544 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
G
|
Casp9
|
caspase 9
|
increases activity multiple interactions
|
ISO EXP
|
Thymol results in increased activity of CASP9 protein Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]
|
CTD |
PMID:21640085 PMID:26996544 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
EXP ISO
|
Thymol inhibits the reaction [imidacloprid results in decreased activity of CAT protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein] Thymol inhibits the reaction [Diethylhexyl Phthalate results in increased activity of CAT protein] Thymol inhibits the reaction [Dietary Fats results in decreased activity of CAT protein]
|
CTD |
PMID:26680107 PMID:26721194 PMID:34171690 PMID:35521929 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
G
|
Ctsk
|
cathepsin K
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of CTSK mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of CTSK protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]
|
CTD |
PMID:30048646 |
|
NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
|
|
G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP11A1 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP17A1 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP19A1 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
increases expression multiple interactions
|
ISO
|
Thymol results in increased expression of CYP1A1 mRNA Thymol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:29191726 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
G
|
Dcstamp
|
dendrocyte expressed seven transmembrane protein
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:72,671,477...72,707,009
|
|
G
|
Dgat2
|
diacylglycerol O-acyltransferase 2
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]
|
CTD |
PMID:36535314 |
|
NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
|
|
G
|
Fas
|
Fas cell surface death receptor
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]
|
CTD |
PMID:26996544 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of FOS mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Thymol promotes the reaction [Lipopolysaccharides results in decreased expression of FOS protein]
|
CTD |
PMID:30048646 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in increased expression of FSHB protein]
|
CTD |
PMID:34171690 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
|
|
G
|
Gab2
|
GRB2-associated binding protein 2
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of GAB2 mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:160,841,066...161,036,940
|
|
G
|
Gabra1
|
gamma-aminobutyric acid type A receptor subunit alpha 1
|
multiple interactions
|
EXP
|
Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
|
CTD |
PMID:11399263 |
|
NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442
|
|
G
|
Gabrb2
|
gamma-aminobutyric acid type A receptor subunit beta 2
|
multiple interactions
|
EXP
|
Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
|
CTD |
PMID:11399263 |
|
NCBI chr10:27,438,127...27,657,680
Ensembl chr10:27,438,238...27,655,171
|
|
G
|
Gabrg2
|
gamma-aminobutyric acid type A receptor subunit gamma 2
|
multiple interactions
|
EXP
|
Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
|
CTD |
PMID:11399263 |
|
NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,876,926...26,965,523
|
|
G
|
Gsr
|
glutathione-disulfide reductase
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Dietary Fats results in decreased activity of GSR protein]
|
CTD |
PMID:26680107 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
G
|
Hsd17b3
|
hydroxysteroid (17-beta) dehydrogenase 3
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of HSD17B3 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283
|
|
G
|
Hspa8
|
heat shock protein family A (Hsp70) member 8
|
multiple interactions
|
ISO
|
Chloroquine inhibits the reaction [Thymol inhibits the reaction [Ethanol results in decreased expression of HSPA8 protein]]; Thymol inhibits the reaction [Ethanol results in decreased expression of HSPA8 protein]
|
CTD |
PMID:36535314 |
|
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
|
|
G
|
Htr3a
|
5-hydroxytryptamine receptor 3A
|
increases activity
|
ISO
|
Thymol results in increased activity of HTR3A protein
|
CTD |
PMID:26456648 |
|
NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884
|
|
G
|
Il10
|
interleukin 10
|
multiple interactions
|
EXP
|
[Thymol co-treated with Fluorouracil] results in increased expression of IL10 protein
|
CTD |
PMID:34665902 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] Thymol inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]
|
CTD |
PMID:26801986 PMID:30048646 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Fluorouracil results in increased expression of IL6 protein]
|
CTD |
PMID:34665902 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in increased expression of LHB protein]
|
CTD |
PMID:34171690 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
G
|
Map1lc3a
|
microtubule-associated protein 1 light chain 3 alpha
|
increases expression multiple interactions
|
ISO
|
Thymol results in increased expression of MAP1LC3A protein Thymol inhibits the reaction [Ethanol results in increased expression of MAP1LC3A protein]
|
CTD |
PMID:36535314 |
|
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
|
|
G
|
Mitf
|
melanocyte inducing transcription factor
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MITF mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 protein]
|
CTD |
PMID:30048646 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MYC mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
G
|
Nfatc1
|
nuclear factor of activated T-cells 1
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of NFATC1 mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of NFATC1 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]
|
CTD |
PMID:30048646 |
|
NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
|
|
G
|
Ogdh
|
oxoglutarate dehydrogenase
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]
|
CTD |
PMID:26721194 |
|
NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
|
|
G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of PCNA protein]
|
CTD |
PMID:34171690 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]
|
CTD |
PMID:34665902 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Fluorouracil results in increased expression of RELA protein]
|
CTD |
PMID:34665902 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
G
|
Sqstm1
|
sequestosome 1
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]
|
CTD |
PMID:36535314 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
|
|
G
|
Src
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
|
|
G
|
Srebf1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein]
|
CTD |
PMID:26680107 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
|
|
G
|
Star
|
steroidogenic acute regulatory protein
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of STAR mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
ISO EXP
|
Thymol inhibits the reaction [Dietary Fats results in increased expression of TGFB1 protein] Thymol inhibits the reaction [Fluorouracil results in increased expression of TGFB1 mRNA]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TGFB1 protein]
|
CTD |
PMID:26680107 PMID:34665902 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO EXP
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] Thymol inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA] Thymol inhibits the reaction [Fluorouracil results in increased expression of TNF mRNA]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TNF protein]
|
CTD |
PMID:26801986 PMID:30048646 PMID:34665902 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
G
|
Tnfrsf11a
|
TNF receptor superfamily member 11A
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF11A mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF11A protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of TNFRSF11A mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257
|
|
G
|
Tnfsf11
|
TNF superfamily member 11
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of GAB2 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MITF mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MYC mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of TNFRSF11A mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
|
|
G
|
Trpv3
|
transient receptor potential cation channel, subfamily V, member 3
|
increases activity
|
ISO
|
Thymol results in increased activity of TRPV3 protein
|
CTD |
PMID:16617338 |
|
NCBI chr10:58,382,054...58,413,657
Ensembl chr10:58,382,054...58,411,800
|
|
G
|
Ugt1a1
|
UDP glucuronosyltransferase family 1 member A1
|
increases glucuronidation
|
ISO
|
UGT1A1 protein results in increased glucuronidation of Thymol
|
CTD |
PMID:14557274 |
|
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
G
|
Ugt1a9
|
UDP glucuronosyltransferase family 1 member A9
|
increases glucuronidation
|
ISO
|
UGT1A9 protein results in increased glucuronidation of Thymol
|
CTD |
PMID:14557274 |
|
NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
G
|
Vegfa
|
vascular endothelial growth factor A
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Dietary Fats results in increased expression of VEGFA protein]
|
CTD |
PMID:26680107 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
|
G
|
Acp5
|
acid phosphatase 5, tartrate resistant
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of ACP5 mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of ACP5 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
|
|
G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions increases activity
|
ISO
|
[4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol co-treated with carvacrol] results in increased activity of AHR protein; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [4-cymene co-treated with gamma-terpinene co-treated with Thymol] results in increased activity of AHR protein; Thymol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] Thymol results in increased activity of AHR protein
|
CTD |
PMID:29191726 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
|
|
G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
affects localization
|
ISO
|
Thymol affects the localization of AIFM1 protein
|
CTD |
PMID:21640085 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression multiple interactions
|
ISO EXP
|
Thymol results in increased expression of BAX protein Thymol inhibits the reaction [imidacloprid results in increased expression of BAX mRNA] Thymol results in increased expression of BAX mRNA
|
CTD |
PMID:21640085 PMID:34171690 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression multiple interactions
|
ISO EXP
|
Thymol results in decreased expression of BCL2 protein Thymol inhibits the reaction [imidacloprid results in decreased expression of BCL2 mRNA]
|
CTD |
PMID:21640085 PMID:34171690 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]
|
CTD |
PMID:26996544 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
G
|
Car2
|
carbonic anhydrase 2
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
G
|
Casp3
|
caspase 3
|
increases activity multiple interactions
|
ISO EXP
|
Thymol results in increased activity of CASP3 protein Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 mRNA]; Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 protein]
|
CTD |
PMID:21640085 PMID:34171690 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
G
|
Casp8
|
caspase 8
|
increases activity multiple interactions
|
ISO EXP
|
Thymol results in increased activity of CASP8 protein Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]
|
CTD |
PMID:21640085 PMID:26996544 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions increases activity
|
EXP ISO
|
Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA] Thymol results in increased activity of CASP9 protein
|
CTD |
PMID:21640085 PMID:26996544 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
ISO EXP
|
Thymol inhibits the reaction [Dietary Fats results in decreased activity of CAT protein] Thymol inhibits the reaction [Diethylhexyl Phthalate results in increased activity of CAT protein] Thymol inhibits the reaction [imidacloprid results in decreased activity of CAT protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]
|
CTD |
PMID:26680107 PMID:26721194 PMID:34171690 PMID:35521929 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
G
|
Ctsk
|
cathepsin K
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of CTSK mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of CTSK protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]
|
CTD |
PMID:30048646 |
|
NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
|
|
G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP11A1 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP17A1 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP19A1 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
ISO
|
Thymol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Thymol results in increased expression of CYP1A1 mRNA
|
CTD |
PMID:29191726 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
G
|
Dcstamp
|
dendrocyte expressed seven transmembrane protein
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:72,671,477...72,707,009
|
|
G
|
Dgat2
|
diacylglycerol O-acyltransferase 2
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]
|
CTD |
PMID:36535314 |
|
NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
|
|
G
|
Fas
|
Fas cell surface death receptor
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]
|
CTD |
PMID:26996544 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of FOS mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Thymol promotes the reaction [Lipopolysaccharides results in decreased expression of FOS protein]
|
CTD |
PMID:30048646 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in increased expression of FSHB protein]
|
CTD |
PMID:34171690 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
|
|
G
|
Gab2
|
GRB2-associated binding protein 2
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of GAB2 mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 1:160,841,066...161,036,940
Ensembl chr 1:160,841,066...161,036,940
|
|
G
|
Gabra1
|
gamma-aminobutyric acid type A receptor subunit alpha 1
|
multiple interactions
|
EXP
|
Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
|
CTD |
PMID:11399263 |
|
NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442
|
|
G
|
Gabrb2
|
gamma-aminobutyric acid type A receptor subunit beta 2
|
multiple interactions
|
EXP
|
Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
|
CTD |
PMID:11399263 |
|
NCBI chr10:27,438,127...27,657,680
Ensembl chr10:27,438,238...27,655,171
|
|
G
|
Gabrg2
|
gamma-aminobutyric acid type A receptor subunit gamma 2
|
multiple interactions
|
EXP
|
Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
|
CTD |
PMID:11399263 |
|
NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,876,926...26,965,523
|
|
G
|
Gsr
|
glutathione-disulfide reductase
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Dietary Fats results in decreased activity of GSR protein]
|
CTD |
PMID:26680107 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
G
|
Hsd17b3
|
hydroxysteroid (17-beta) dehydrogenase 3
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of HSD17B3 mRNA]
|
CTD |
PMID:34171690 |
|
NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283
|
|
G
|
Hspa8
|
heat shock protein family A (Hsp70) member 8
|
multiple interactions
|
ISO
|
Chloroquine inhibits the reaction [Thymol inhibits the reaction [Ethanol results in decreased expression of HSPA8 protein]]; Thymol inhibits the reaction [Ethanol results in decreased expression of HSPA8 protein]
|
CTD |
PMID:36535314 |
|
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
|
|
G
|
Htr3a
|
5-hydroxytryptamine receptor 3A
|
increases activity
|
ISO
|
Thymol results in increased activity of HTR3A protein
|
CTD |
PMID:26456648 |
|
NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884
|
|
G
|
Il10
|
interleukin 10
|
multiple interactions
|
EXP
|
[Thymol co-treated with Fluorouracil] results in increased expression of IL10 protein
|
CTD |
PMID:34665902 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] Thymol inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]
|
CTD |
PMID:26801986 PMID:30048646 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Fluorouracil results in increased expression of IL6 protein]
|
CTD |
PMID:34665902 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in increased expression of LHB protein]
|
CTD |
PMID:34171690 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
|
|
G
|
Map1lc3a
|
microtubule-associated protein 1 light chain 3 alpha
|
increases expression multiple interactions
|
ISO
|
Thymol results in increased expression of MAP1LC3A protein Thymol inhibits the reaction [Ethanol results in increased expression of MAP1LC3A protein]
|
CTD |
PMID:36535314 |
|
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850
|
|
G
|
Mitf
|
melanocyte inducing transcription factor
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MITF mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 protein]
|
CTD |
PMID:30048646 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MYC mRNA]
|
CTD |
PMID:30048646 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
G
|
Nfatc1
|
nuclear factor of activated T-cells 1
|
multiple interactions
|
ISO
|
Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of NFATC1 mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of NFATC1 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]
|
CTD |
PMID:30048646 |
|
NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
|
|
G
|
Ogdh
|
oxoglutarate dehydrogenase
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]
|
CTD |
PMID:26721194 |
|
NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
|
|
G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [imidacloprid results in decreased expression of PCNA protein]
|
CTD |
PMID:34171690 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]
|
CTD |
PMID:34665902 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
Thymol inhibits the reaction [Fluorouracil results in increased expression of RELA protein]
|
CTD |
PMID:34665902 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
G
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Sqstm1
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sequestosome 1
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multiple interactions
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ISO
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Thymol inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]
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CTD |
PMID:36535314 |
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NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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G
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Src
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SRC proto-oncogene, non-receptor tyrosine kinase
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multiple interactions
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ISO
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Thymol inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]
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CTD |
PMID:30048646 |
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NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
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G
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Srebf1
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sterol regulatory element binding transcription factor 1
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multiple interactions
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ISO
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Thymol inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein]
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CTD |
PMID:26680107 |
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NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
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G
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Star
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steroidogenic acute regulatory protein
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multiple interactions
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EXP
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Thymol inhibits the reaction [imidacloprid results in decreased expression of STAR mRNA]
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CTD |
PMID:34171690 |
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NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
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G
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Tgfb1
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transforming growth factor, beta 1
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multiple interactions
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ISO EXP
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Thymol inhibits the reaction [Dietary Fats results in increased expression of TGFB1 protein] Thymol inhibits the reaction [Fluorouracil results in increased expression of TGFB1 mRNA]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TGFB1 protein]
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CTD |
PMID:26680107 PMID:34665902 |
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NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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G
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Tnf
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tumor necrosis factor
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multiple interactions
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ISO EXP
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Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] Thymol inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA] Thymol inhibits the reaction [Fluorouracil results in increased expression of TNF mRNA]; Thymol inhibits the reaction [Fluorouracil results in increased expression of TNF protein]
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CTD |
PMID:26801986 PMID:30048646 PMID:34665902 |
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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G
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Tnfrsf11a
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TNF receptor superfamily member 11A
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multiple interactions
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ISO
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Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF11A mRNA]; Thymol inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF11A protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of TNFRSF11A mRNA]
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CTD |
PMID:30048646 |
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NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257
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G
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Tnfsf11
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TNF superfamily member 11
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multiple interactions
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ISO
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Thymol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of GAB2 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MITF mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MYC mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Thymol inhibits the reaction [TNFSF11 protein results in increased expression of TNFRSF11A mRNA]
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CTD |
PMID:30048646 |
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NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
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G
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Trpv3
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transient receptor potential cation channel, subfamily V, member 3
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increases activity
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ISO
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Thymol results in increased activity of TRPV3 protein
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CTD |
PMID:16617338 |
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NCBI chr10:58,382,054...58,413,657
Ensembl chr10:58,382,054...58,411,800
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G
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Ugt1a1
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UDP glucuronosyltransferase family 1 member A1
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increases glucuronidation
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ISO
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UGT1A1 protein results in increased glucuronidation of Thymol
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CTD |
PMID:14557274 |
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NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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G
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Ugt1a9
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UDP glucuronosyltransferase family 1 member A9
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increases glucuronidation
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ISO
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UGT1A9 protein results in increased glucuronidation of Thymol
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CTD |
PMID:14557274 |
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NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
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G
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Vegfa
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vascular endothelial growth factor A
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multiple interactions
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ISO
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Thymol inhibits the reaction [Dietary Fats results in increased expression of VEGFA protein]
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CTD |
PMID:26680107 |
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NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
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