CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | fructose |
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Accession: | CHEBI:28757
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browse the term
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Definition: | A ketohexose that is an isomer of glucose. |
Synonyms: | exact_synonym: | arabino-hex-2-ulose |
| related_synonym: | Fru; Fruchtzucker; Fruktose; arabino-Hexulose |
| alt_id: | CHEBI:24104; CHEBI:24110; CHEBI:5172 |
| xref: | CAS:30237-26-4; DrugBank:DB04173; KEGG:C01496 |
| xref_mesh: | MESH:D005632 |
| xref: | Wikipedia:Fructose |
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A1bg |
alpha-1-B glycoprotein |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of A1BG protein |
CTD |
PMID:26930160 |
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NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
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A2m |
alpha-2-macroglobulin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of A2M mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786
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Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression |
EXP |
Tea inhibits the reaction [Fructose results in increased expression of ABCA1 mRNA] |
CTD |
PMID:19193814 |
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NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170
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Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ABCB4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202
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Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions decreases expression |
EXP |
Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 protein]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] Fructose results in decreased expression of ABCC2 mRNA; Fructose results in decreased expression of ABCC2 protein |
CTD |
PMID:31005848 |
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
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Abcd2 |
ATP binding cassette subfamily D member 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ABCD2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:122,263,032...122,311,642
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Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions decreases phosphorylation increases expression |
ISO EXP |
FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]; Phenylbutyrates inhibits the reaction [Fructose results in increased expression of ACACA mRNA]; SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of ACACA mRNA] [Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form; [Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein] Fructose results in decreased phosphorylation of ACACA protein [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased activity of SIRT1 protein] inhibits the reaction [Fructose results in increased expression of ACACA mRNA]; [Niacinamide results in decreased activity of SIRT1 protein] inhibits the reaction [Fructose results in increased expression of ACACA mRNA]; bisphenol A promotes the reaction [Fructose results in increased expression of ACACA mRNA]; Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Fructose promotes the reaction [bisphenol A results in increased expression of ACACA mRNA]; Rotenone inhibits the reaction [Fructose results in increased expression of ACACA mRNA] |
CTD |
PMID:1973097 PMID:15066988 PMID:21212096 PMID:22698815 PMID:28123933 PMID:31661889 PMID:31672515 PMID:32730863 More...
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NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
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Acacb |
acetyl-CoA carboxylase beta |
decreases expression increases expression multiple interactions |
ISO EXP |
Fructose results in decreased expression of ACACB mRNA Fructose results in increased expression of ACACB mRNA FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACB mRNA] |
CTD |
PMID:18063403 PMID:19053045 PMID:28123933 |
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NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
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Acadl |
acyl-CoA dehydrogenase, long chain |
multiple interactions |
EXP |
[Fructose co-treated with Copper deficiency] results in decreased expression of ACADL mRNA |
CTD |
PMID:25813056 |
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NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:68,333,980...68,372,220
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Acadm |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
EXP |
[Fructose co-treated with Copper deficiency] results in decreased expression of ACADM mRNA |
CTD |
PMID:25813056 |
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NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147
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Acads |
acyl-CoA dehydrogenase short chain |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of ACADS protein |
CTD |
PMID:26930160 |
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NCBI chr12:47,154,259...47,163,580
Ensembl chr12:41,493,626...41,502,898
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Acadvl |
acyl-CoA dehydrogenase, very long chain |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of ACADVL protein; [Fructose co-treated with Copper deficiency] results in decreased expression of ACADVL mRNA |
CTD |
PMID:25813056 PMID:26930160 |
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NCBI chr10:55,231,558...55,236,786
Ensembl chr10:54,732,469...54,738,075
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Ace |
angiotensin I converting enzyme |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of ACE mRNA [bisphenol A co-treated with Fructose] results in increased expression of ACE mRNA; APLN protein modified form inhibits the reaction [Fructose results in increased expression of ACE mRNA] |
CTD |
PMID:17587757 PMID:27622962 PMID:30710622 |
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NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131
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Ache |
acetylcholinesterase |
multiple interactions |
EXP |
[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein] |
CTD |
PMID:33823243 |
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NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
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Acly |
ATP citrate lyase |
increases expression |
EXP |
Fructose results in increased expression of ACLY mRNA |
CTD |
PMID:1396700 |
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NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
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Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ACOT1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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Acox1 |
acyl-CoA oxidase 1 |
multiple interactions decreases expression |
EXP |
Atorvastatin inhibits the reaction [Fructose results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:21122807 |
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NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232
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Acsbg1 |
acyl-CoA synthetase bubblegum family member 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ACSBG1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
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Acsf2 |
acyl-CoA synthetase family member 2 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of ACSF2 protein |
CTD |
PMID:26930160 |
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NCBI chr10:80,001,389...80,043,796
Ensembl chr10:79,504,511...79,546,673
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Acsm3 |
acyl-CoA synthetase medium-chain family member 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ACSM3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:174,133,288...174,160,184
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Acta1 |
actin, alpha 1, skeletal muscle |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ACTA1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:68,781,168...68,784,194
Ensembl chr19:51,883,715...51,886,742
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Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
EXP ISO |
Fructose results in increased expression of ACTA2 protein [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of ACTA2 mRNA; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of ACTA2 protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of ACTA2 mRNA [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ACTA2 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of ACTA2 protein; [Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; Genistein inhibits the reaction [Fructose results in increased expression of ACTA2 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]] |
CTD |
PMID:21704028 PMID:30551545 PMID:34939712 PMID:37271273 |
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NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
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Ada |
adenosine deaminase |
multiple interactions increases activity |
EXP |
Glutamine inhibits the reaction [Fructose results in increased activity of ADA protein] |
CTD |
PMID:31233715 |
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NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088
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Adam19 |
ADAM metallopeptidase domain 19 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ADAM19 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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Adam32 |
ADAM metallopeptidase domain 32 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ADAM32 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161
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Adam7 |
ADAM metallopeptidase domain 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of ADAM7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201
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Adam8 |
ADAM metallopeptidase domain 8 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADAM8 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:194,770,060...194,788,801
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Adgra1 |
adhesion G protein-coupled receptor A1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADGRA1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:194,629,744...194,673,254
Ensembl chr 1:194,629,726...194,672,550
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Adgrb1 |
adhesion G protein-coupled receptor B1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADGRB1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:108,293,681...108,365,892
Ensembl chr 7:106,404,958...106,476,902
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Adgre1 |
adhesion G protein-coupled receptor E1 |
multiple interactions increases expression |
EXP ISO |
[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of ADGRE1 mRNA Fructose results in increased expression of ADGRE1 protein Ethanol promotes the reaction [Fructose results in increased expression of ADGRE1 protein]; Fructose promotes the reaction [Ethanol results in increased expression of ADGRE1 mRNA]; Fructose promotes the reaction [Ethanol results in increased expression of ADGRE1 protein] |
CTD |
PMID:25813056 PMID:26858005 |
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NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,242,474...2,398,000
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Adgre4 |
adhesion G protein-coupled receptor E4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADGRE4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760
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Adgrf4 |
adhesion G protein-coupled receptor F4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ADGRF4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:18,272,050...18,303,219
Ensembl chr 9:18,272,050...18,303,217
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Adgrg4 |
adhesion G protein-coupled receptor G4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ADGRG4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:134,734,610...134,864,449
Ensembl chr X:134,854,736...134,864,449
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Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions decreases secretion increases secretion decreases expression increases expression |
EXP ISO |
[Particulate Matter co-treated with Ozone] promotes the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; bisphenol A promotes the reaction [Fructose results in decreased expression of ADIPOQ protein]; Curcumin inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein]; Fructose promotes the reaction [bisphenol A results in decreased expression of ADIPOQ protein]; geraniol inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; Metformin inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein]; Ozone promotes the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; Particulate Matter promotes the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; Pioglitazone inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; Resveratrol inhibits the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; Resveratrol inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein]; sapropterin inhibits the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; sapropterin inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein]; TNF protein affects the reaction [Fructose results in increased expression of ADIPOQ protein] Fructose results in increased secretion of ADIPOQ protein Fructose results in decreased expression of ADIPOQ mRNA; Fructose results in decreased expression of ADIPOQ protein Fructose results in increased expression of ADIPOQ mRNA; Fructose results in increased expression of ADIPOQ protein |
CTD |
PMID:17098227 PMID:19165636 PMID:21122807 PMID:23016136 PMID:23968387 PMID:25108154 PMID:25679220 PMID:26713546 PMID:26973390 PMID:28257781 PMID:31661889 PMID:33118400 More...
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NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564
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Adipor2 |
adiponectin receptor 2 |
decreases expression |
ISO |
Fructose results in decreased expression of ADIPOR2 protein |
CTD |
PMID:28257781 |
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NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:152,524,623...152,559,355
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Adrb3 |
adrenoceptor beta 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADRB3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:71,544,603...71,547,410
Ensembl chr16:64,841,788...64,844,552
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Agbl4 |
AGBL carboxypeptidase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of AGBL4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:130,483,551...131,762,906
Ensembl chr 5:125,254,956...126,534,367
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Ager |
advanced glycosylation end product-specific receptor |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of AGER protein Genistein inhibits the reaction [Fructose results in increased expression of AGER protein]; geraniol inhibits the reaction [Fructose results in increased expression of AGER protein]; Pioglitazone inhibits the reaction [Fructose results in increased expression of AGER protein] |
CTD |
PMID:21704028 PMID:25679220 |
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NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078
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Agt |
angiotensinogen |
increases expression multiple interactions |
EXP ISO |
Fructose results in increased expression of AGT mRNA; Fructose results in increased expression of AGT protein; Fructose results in increased expression of AGT protein modified form APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT mRNA]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT protein modified form]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT protein] |
CTD |
PMID:11741341 PMID:16843071 PMID:17587757 PMID:18360027 PMID:30710622 |
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NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977
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Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions increases expression |
EXP ISO |
APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA]; INS protein inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA] Fructose results in increased expression of AGTR1 mRNA |
CTD |
PMID:16843071 PMID:17587757 PMID:18360027 PMID:30710622 PMID:31655124 |
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NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946
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Agtr1b |
angiotensin II receptor, type 1b |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of AGTR1B mRNA KLK1 protein inhibits the reaction [Fructose results in increased expression of AGTR1B mRNA] |
CTD |
PMID:14568997 |
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NCBI chr 2:104,774,005...104,849,262
Ensembl chr 2:102,844,969...102,920,232
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Agtr2 |
angiotensin II receptor, type 2 |
multiple interactions increases expression |
EXP |
APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGTR2 mRNA] |
CTD |
PMID:30710622 |
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NCBI chr X:116,914,320...116,918,504
Ensembl chr X:112,120,228...112,124,057
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Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of AHR mRNA; AHR protein results in increased susceptibility to [Dietary Fats co-treated with Fructose]; NR0B2 protein inhibits the reaction [AHR protein results in increased susceptibility to [Dietary Fats co-treated with Fructose]]; PEMT protein promotes the reaction [AHR protein results in increased susceptibility to [Dietary Fats co-treated with Fructose]] |
CTD |
PMID:29416063 |
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NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,646,777...3,652,668
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Akr1b1 |
aldo-keto reductase family 1 member B1 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of AKR1B1 protein |
CTD |
PMID:26930160 |
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NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157
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Akr1c1 |
aldo-keto reductase family 1, member C1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of AKR1C6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326
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Akr1c3 |
aldo-keto reductase family 1, member C3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of AKR1C18 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873
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Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation multiple interactions increases phosphorylation |
EXP |
Fructose results in decreased phosphorylation of AKT1 protein [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of AKT1 protein]; [Fructose co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of AKT1 protein; [Fructose co-treated with Oleanolic Acid] results in increased expression of AKT1 mRNA; NOS3 protein inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Fructose results in increased phosphorylation of AKT1 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:18497449 PMID:19008412 PMID:22426011 PMID:23533474 PMID:24704288 PMID:32259528 More...
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NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
ISO |
[Fructose co-treated with Glucose] results in increased glycation of ALB protein; pimagedine inhibits the reaction [[Fructose co-treated with Glucose] results in increased glycation of ALB protein]; ursonic acid inhibits the reaction [[Fructose co-treated with Glucose] results in increased glycation of ALB protein] |
CTD |
PMID:36933777 |
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NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1l2 |
aldehyde dehydrogenase 1 family, member L2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ALDH1L2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:20,254,233...20,305,776
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G |
Aldh3b3 |
aldehyde dehydrogenase 3 family, member B3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALDH3B3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:210,617,090...210,629,886
Ensembl chr 1:201,187,962...201,250,204
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G |
Aldob |
aldolase, fructose-bisphosphate B |
increases expression multiple interactions |
ISO EXP |
Fructose results in increased expression of ALDOB mRNA FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of ALDOB mRNA] |
CTD |
PMID:15066988 PMID:18346472 PMID:28123933 |
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NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116
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G |
Aldoc |
aldolase, fructose-bisphosphate C |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ALDOA mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066
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G |
Alk |
ALK receptor tyrosine kinase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ALK mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034
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G |
Alox5 |
arachidonate 5-lipoxygenase |
increases expression |
ISO |
Fructose results in increased expression of ALOX5 mRNA |
CTD |
PMID:31655124 |
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NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:149,531,515...149,578,743
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G |
Alpk3 |
alpha-kinase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALPK3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:144,423,690...144,471,534
Ensembl chr 1:135,014,499...135,062,302
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G |
Amer2 |
APC membrane recruitment protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of AMER2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:34,525,352...34,535,660
Ensembl chr15:34,524,542...34,528,455
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G |
Anks1b |
ankyrin repeat and sterile alpha motif domain containing 1B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ANKS1B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:26,200,649...27,366,552
Ensembl chr 7:24,312,843...25,477,693
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G |
Aoc1 |
amine oxidase, copper containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of AOC1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of AOC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:77,812,260...77,831,840
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
ISO |
[Fructose co-treated with Dietary Fats] results in increased expression of APAF1 mRNA; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of APAF1 mRNA] |
CTD |
PMID:28916335 |
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NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540
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G |
Apcs |
amyloid P component, serum |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of APCS mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:87,905,532...87,906,508
Ensembl chr13:85,373,220...85,374,298
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G |
Apln |
apelin |
multiple interactions |
EXP |
APLN protein modified form inhibits the reaction [Fructose results in decreased activity of CAT protein]; APLN protein modified form inhibits the reaction [Fructose results in decreased expression of APLNR mRNA]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of ACE mRNA]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT mRNA]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT protein modified form]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT protein]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA]; APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGTR2 mRNA] |
CTD |
PMID:30710622 |
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NCBI chr X:132,058,739...132,091,518
Ensembl chr X:127,203,823...127,213,391
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G |
Aplnr |
apelin receptor |
decreases expression multiple interactions |
EXP |
Fructose results in decreased expression of APLNR mRNA APLN protein modified form inhibits the reaction [Fructose results in decreased expression of APLNR mRNA] |
CTD |
PMID:30710622 |
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NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:70,217,385...70,221,050
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G |
Apoa1 |
apolipoprotein A1 |
increases expression multiple interactions decreases expression |
EXP ISO |
Fructose results in increased expression of APOA1 mRNA; Fructose results in increased expression of APOA1 protein Plant Preparations inhibits the reaction [Fructose results in decreased expression of APOA1 protein] [bisphenol A co-treated with Fructose] results in increased expression of APOA1 protein |
CTD |
PMID:9322794 PMID:23142792 PMID:27531227 |
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NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoa4 |
apolipoprotein A4 |
increases expression |
ISO |
Fructose results in increased expression of APOA4 mRNA |
CTD |
PMID:11983814 |
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NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469
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G |
Apob |
apolipoprotein B |
multiple interactions increases expression |
EXP ISO |
[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA; Atorvastatin inhibits the reaction [Fructose results in increased expression of APOB protein]; gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA] [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in decreased expression of APOB mRNA; Plant Preparations inhibits the reaction [Fructose results in increased expression of APOB protein] Fructose results in increased expression of APOB mRNA; Fructose results in increased expression of APOB protein |
CTD |
PMID:8415773 PMID:12065722 PMID:25813056 PMID:27531227 PMID:28123933 |
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NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of APOE mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
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G |
Apol9a |
apolipoprotein L9a |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of APOL9A mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:111,021,452...111,030,380
Ensembl chr 7:109,140,871...109,147,649
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G |
Aqp5 |
aquaporin 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of AQP5 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of AQP5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:130,721,748...130,726,209
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G |
Aqp8 |
aquaporin 8 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of AQP8 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:177,993,305...177,999,158
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
[2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of AR protein |
CTD |
PMID:37615203 |
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NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925
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G |
Arc |
activity-regulated cytoskeleton-associated protein |
decreases expression |
EXP |
Fructose results in decreased expression of ARC mRNA |
CTD |
PMID:37121297 |
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NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of AREG mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:17,256,384...17,265,641
Ensembl chr14:16,972,187...16,981,535
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G |
Arl5c |
ARF like GTPase 5C |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ARL5C mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:82,985,213...82,993,425
Ensembl chr10:82,985,216...82,992,002
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G |
Arsj |
arylsulfatase family, member J |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of ARSJ mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:214,774,631...214,854,614
Ensembl chr 2:214,774,654...214,854,612
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G |
Ascl1 |
achaete-scute family bHLH transcription factor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ASCL1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:21,903,126...21,905,993
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G |
Asmt |
acetylserotonin O-methyltransferase |
increases expression |
EXP |
Fructose results in increased expression of ASMT mRNA |
CTD |
PMID:37121297 |
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NCBI chr12:16,304,719...16,309,568
Ensembl chr12:16,304,719...16,309,568
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G |
Aspg |
asparaginase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ASPG mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:131,176,874...131,196,268
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G |
Aspn |
asporin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ASPN mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:15,286,338...15,310,567
Ensembl chr17:15,080,639...15,104,041
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ATF3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression |
EXP |
Fructose results in increased expression of ATF4 mRNA |
CTD |
PMID:15150374 |
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NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
EXP |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein] |
CTD |
PMID:34801538 PMID:34939712 |
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NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177
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G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
decreases expression |
EXP |
Fructose results in decreased expression of ATP1B1 protein |
CTD |
PMID:26930160 |
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NCBI chr13:79,319,708...79,340,226
Ensembl chr13:76,786,578...76,807,459
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions |
ISO |
[Fructose co-treated with Dietary Fats] results in decreased expression of ATP2A2 mRNA; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of ATP2A2 mRNA] |
CTD |
PMID:28916335 |
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NCBI chr12:39,733,519...39,782,942
Ensembl chr12:34,072,683...34,122,101
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G |
Atp5mf |
ATP synthase membrane subunit f |
multiple interactions increases expression |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of ATP5MF protein Fructose results in increased expression of ATP5MF protein |
CTD |
PMID:26930160 |
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NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
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G |
Azgp1 |
alpha-2-glycoprotein 1, zinc-binding |
multiple interactions decreases expression |
EXP |
[bisphenol A co-treated with Fructose] results in decreased expression of AZGP1 protein Fructose results in decreased expression of AZGP1 protein |
CTD |
PMID:31661889 |
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NCBI chr12:22,044,685...22,051,248
Ensembl chr12:16,931,024...16,939,091
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G |
B2m |
beta-2 microglobulin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of B2M mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766
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G |
B3gnt6 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of B3GNT6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:161,897,504...161,915,046
Ensembl chr 1:152,486,343...152,492,150
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G |
B4galnt4 |
beta-1,4-N-acetyl-galactosaminyl transferase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of B4GALNT4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of BAK1 protein Plant Extracts inhibits the reaction [Fructose results in increased expression of BAK1 protein] |
CTD |
PMID:33475235 |
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NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264
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G |
Barx2 |
BARX homeobox 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of BARX2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:38,509,277...38,576,978
Ensembl chr 8:30,251,132...30,319,013
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G |
Batf2 |
basic leucine zipper ATF-like transcription factor 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BATF2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:212,897,076...212,905,740
Ensembl chr 1:203,468,097...203,475,889
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
Fructose results in increased expression of BAX protein Plant Extracts inhibits the reaction [Fructose results in increased expression of BAX protein] [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of BAX protein; [Fructose co-treated with Dietary Fats] results in increased expression of BAX mRNA; [Fructose co-treated with Dietary Fats] results in increased expression of BAX protein; Plant Preparations inhibits the reaction [Fructose results in increased expression of BAX protein]; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of BAX mRNA]; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of BAX protein] |
CTD |
PMID:27531227 PMID:28916335 PMID:33475235 PMID:37271273 |
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NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
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G |
Baz2b |
bromodomain adjacent to zinc finger domain, 2B |
increases expression |
EXP |
Fructose results in increased expression of BAZ2B mRNA |
CTD |
PMID:36049592 |
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NCBI chr 3:64,792,984...65,034,547
Ensembl chr 3:44,385,474...44,592,908
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G |
Bcl11a |
BCL11 transcription factor A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of BCL11A mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:102,230,147...102,325,289
Ensembl chr14:98,030,461...98,124,180
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression increases expression multiple interactions |
ISO EXP |
Fructose results in decreased expression of BCL2 protein Fructose results in increased expression of BCL2 mRNA [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein]; [Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein]; Kangen-karyu inhibits the reaction [Fructose results in increased expression of BCL2 protein] [Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA; [Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA]; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of BCL2 protein] |
CTD |
PMID:17883899 PMID:27531227 PMID:28916335 PMID:31655124 PMID:32259528 |
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions decreases expression |
EXP |
Plant Extracts inhibits the reaction [Fructose results in decreased expression of BCL2L1 protein] |
CTD |
PMID:33475235 |
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NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Bco1 |
beta-carotene oxygenase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of BCO1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:62,058,061...62,094,923
Ensembl chr19:45,149,265...45,186,101
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G |
Begain |
brain-enriched guanylate kinase-associated |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of BEGAIN mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of BHMT mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742
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G |
Bmper |
BMP-binding endothelial regulator |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BMPER mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
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G |
Bst2 |
bone marrow stromal cell antigen 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BST2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,217,407...18,220,979
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G |
Btbd17 |
BTB domain containing 17 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of BTBD17 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:99,826,132...99,832,624
Ensembl chr10:99,826,132...99,832,624
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G |
C3 |
complement C3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of C3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of C3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429
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G |
C4b |
complement C4B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of C4B mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,197,366...4,211,681
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G |
C5 |
complement C5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of HC mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of HC mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:18,270,696...18,361,994
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G |
C5ar1 |
complement C5a receptor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of C5AR1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:86,077,309...86,088,001
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G |
Cabp4 |
calcium binding protein 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CABP4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:210,857,223...210,872,431
Ensembl chr 1:201,428,672...201,433,172
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G |
Cacna1s |
calcium voltage-gated channel subunit alpha1 S |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CACNA1S mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:50,045,668...50,115,903
Ensembl chr13:47,493,949...47,564,318
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G |
Calca |
calcitonin-related polypeptide alpha |
increases expression multiple interactions |
ISO |
Fructose results in increased expression of CALCA mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CALCA mRNA |
CTD |
PMID:31655124 PMID:37567420 |
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NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:168,878,214...168,883,105
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G |
Camsap3 |
calmodulin regulated spectrin-associated protein family, member 3 |
decreases expression |
EXP |
Fructose results in decreased expression of CAMSAP3 mRNA |
CTD |
PMID:36049592 |
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NCBI chr12:6,440,959...6,464,582
Ensembl chr12:1,643,251...1,666,685
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G |
Canx |
calnexin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein] |
CTD |
PMID:34801538 |
|
NCBI chr10:35,124,941...35,157,954
Ensembl chr10:34,625,191...34,656,821
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G |
Car3 |
carbonic anhydrase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CAR3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280
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G |
Cartpt |
CART prepropeptide |
decreases expression |
EXP |
Fructose results in decreased expression of CARTPT mRNA |
CTD |
PMID:37121297 |
|
NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713
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G |
Casp1 |
caspase 1 |
multiple interactions increases expression |
EXP |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CASP1 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of CASP1 protein; Allopurinol inhibits the reaction [Fructose results in increased expression of CASP1 protein modified form]; Allopurinol inhibits the reaction [Fructose results in increased expression of CASP1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CASP1 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of CASP1 protein modified form]; Quercetin inhibits the reaction [Fructose results in increased expression of CASP1 protein]; Rutin inhibits the reaction [Fructose results in increased expression of CASP1 protein] Fructose results in increased expression of CASP1 protein; Fructose results in increased expression of CASP1 protein modified form |
CTD |
PMID:22426011 PMID:24491314 PMID:34939712 |
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NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
multiple interactions decreases cleavage decreases expression increases expression |
ISO EXP |
[Fructose co-treated with Dietary Fats] results in increased expression of CASP3 mRNA; [Fructose co-treated with Dietary Fats] results in increased expression of CASP3 protein; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CASP3 protein] Fructose results in decreased cleavage of CASP3 protein [Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein] Fructose results in decreased expression of CASP3 mRNA imoxin inhibits the reaction [Fructose results in increased expression of CASP3 protein]; Plant Extracts inhibits the reaction [Fructose results in decreased cleavage of CASP3 protein] |
CTD |
PMID:28916335 PMID:29430716 PMID:31655124 PMID:32730863 PMID:33475235 |
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]] |
CTD |
PMID:30551545 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
decreases cleavage multiple interactions |
EXP |
Fructose results in decreased cleavage of CASP8 protein Plant Extracts inhibits the reaction [Fructose results in decreased cleavage of CASP8 protein] |
CTD |
PMID:33475235 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions decreases cleavage |
ISO EXP |
[Fructose co-treated with Dietary Fats] results in increased expression of CASP9 mRNA; [Fructose co-treated with Dietary Fats] results in increased expression of CASP9 protein; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CASP9 mRNA]; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CASP9 protein] Plant Extracts inhibits the reaction [Fructose results in decreased cleavage of CASP9 protein] |
CTD |
PMID:28916335 PMID:33475235 |
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Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
decreases expression multiple interactions decreases activity |
EXP ISO |
Fructose results in decreased expression of CAT mRNA; Fructose results in decreased expression of CAT protein [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in decreased expression of CAT protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in decreased expression of CAT protein; [Fructose co-treated with Dietary Fats] results in decreased activity of CAT protein; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased activity of CAT protein] [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Hydrochlorothiazide co-treated with Fructose] results in decreased activity of CAT protein; APLN protein modified form inhibits the reaction [Fructose results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein] |
CTD |
PMID:11817707 PMID:20470786 PMID:23707192 PMID:28916335 PMID:30710622 PMID:33823243 PMID:37271273 More...
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cavin3 |
caveolae associated protein 3 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of CAVIN3 protein |
CTD |
PMID:26930160 |
|
NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161
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G |
Ccdc169 |
coiled-coil domain containing 169 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CCDC169 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:139,321,644...139,351,161
Ensembl chr 2:139,321,670...139,351,161
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G |
Ccdc190 |
coiled-coil domain containing 190 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CCDC190 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:82,147,161...82,154,863
Ensembl chr13:82,147,176...82,154,863
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression increases secretion |
ISO EXP |
[Fructose co-treated with Uric Acid] results in increased secretion of CCL2 protein; acetovanillone inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Allopurinol inhibits the reaction [[Fructose co-treated with Uric Acid] results in increased secretion of CCL2 protein]; Allopurinol inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Glucose inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; KHK protein promotes the reaction [Fructose results in increased secretion of CCL2 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Superoxides affects the reaction [Fructose results in increased secretion of CCL2 protein] Fructose results in increased expression of CCL2 mRNA Fructose results in increased expression of CCL2 protein [Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of CCL2 mRNA; [Fructose co-treated with Ethanol] results in increased expression of CCL2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCL2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CCL2 mRNA; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein] [Copper deficiency co-treated with Fructose] results in increased expression of CCL2 protein; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein; [Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein; [Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein; [Particulate Matter co-treated with Ozone] promotes the reaction [Fructose results in increased expression of CCL2 mRNA]; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 mRNA]; Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Deferiprone inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein]; Deferoxamine inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein]; Fish Oils inhibits the reaction [Fructose results in increased expression of CCL2 protein]; gadolinium chloride inhibits the reaction [[Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Ozone promotes the reaction [Fructose results in increased expression of CCL2 mRNA]; Particulate Matter promotes the reaction [Fructose results in increased expression of CCL2 mRNA] Fructose results in increased expression of CCL2 mRNA; Fructose results in increased expression of CCL2 protein |
CTD |
PMID:15752949 PMID:17133782 PMID:19158351 PMID:21781943 PMID:23968387 PMID:25813056 PMID:26824242 PMID:26858005 PMID:28123933 PMID:30551545 PMID:31655124 PMID:31672515 PMID:34939712 PMID:37567420 More...
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NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl28 |
C-C motif chemokine ligand 28 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CCL28 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:53,334,071...53,358,709
Ensembl chr 2:51,601,331...51,625,997
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of CCL3 mRNA |
CTD |
PMID:28123933 |
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NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CCL7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions increases expression |
EXP |
betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] |
CTD |
PMID:25559852 |
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NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCNB1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccr6 |
C-C motif chemokine receptor 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CCR6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:52,474,168...52,498,603
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCR7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309
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G |
Cd163 |
CD163 molecule |
multiple interactions |
EXP ISO |
[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of CD163 mRNA [Fructose co-treated with Ethanol] results in increased expression of CD163 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD163 mRNA |
CTD |
PMID:25813056 PMID:26858005 PMID:37567420 |
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NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878
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G |
Cd19 |
CD19 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CD19 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CD19 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:180,987,286...180,993,975
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G |
Cd226 |
CD226 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD226 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:84,723,330...84,819,836
Ensembl chr18:82,450,568...82,543,051
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G |
Cd247 |
Cd247 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD247 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:80,576,264...80,651,422
Ensembl chr13:78,043,307...78,122,263
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G |
Cd300a |
Cd300a molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD300A mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:100,428,826...100,441,693
Ensembl chr10:99,929,801...99,942,674
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G |
Cd300lb |
CD300 molecule-like family member b |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CD300LB mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:100,463,815...100,473,804
Ensembl chr10:99,964,801...99,974,790
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G |
Cd36 |
CD36 molecule |
decreases expression multiple interactions |
ISO EXP |
Fructose results in decreased expression of CD36 protein [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CD36 protein]; [Fructose co-treated with Dietary Fats] results in increased expression of CD36 protein; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CD36 protein] |
CTD |
PMID:28257781 PMID:32259528 |
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NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd3e |
CD3 epsilon subunit of T-cell receptor complex |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD3E mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022
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G |
Cd40lg |
CD40 ligand |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD40LG mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:140,164,341...140,176,057
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CD44 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd48 |
Cd48 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD48 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:86,717,960...86,741,540
Ensembl chr13:84,185,532...84,209,142
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G |
Cd5 |
Cd5 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:216,790,245...216,811,209
Ensembl chr 1:207,365,337...207,386,313
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G |
Cd52 |
CD52 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:146,319,969...146,321,348
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G |
Cd6 |
Cd6 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:216,867,767...216,906,642
Ensembl chr 1:207,442,877...207,481,634
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G |
Cd68 |
Cd68 molecule |
multiple interactions |
EXP ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of CD68 mRNA; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of CD68 mRNA; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of CD68 protein [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of CD68 mRNA; [Fructose co-treated with Ethanol] results in increased expression of CD68 mRNA |
CTD |
PMID:19632207 PMID:25813056 PMID:26858005 PMID:28123933 |
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NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697
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G |
Cd74 |
CD74 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD74 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
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G |
Cd8b |
CD8 subunit beta |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD8B1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:104,870,911...104,886,838
Ensembl chr 4:103,312,578...103,328,553
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G |
Cd96 |
CD96 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD96 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr11:68,164,926...68,239,266
Ensembl chr11:54,702,290...54,776,621
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G |
Cdh1 |
cadherin 1 |
multiple interactions |
EXP |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of CDH1 protein]; [Dietary Fats co-treated with Fructose] results in decreased expression of CDH1 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of CDH1 protein] |
CTD |
PMID:34939712 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CDK1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CDK1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408
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G |
Ceacam1 |
CEA cell adhesion molecule 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CEACAM3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992
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G |
Ceacam19 |
CEA cell adhesion molecule 19 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CEACAM19 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:79,542,107...79,550,927
Ensembl chr 1:79,542,107...79,550,927
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G |
Celf3 |
CUGBP, Elav-like family member 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CELF3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:184,805,078...184,819,189
Ensembl chr 2:182,116,073...182,130,163
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G |
Celf4 |
CUGBP, Elav-like family member 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELF4 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786
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G |
Celsr3 |
cadherin, EGF LAG seven-pass G-type receptor 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CELSR3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELSR3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:118,409,136...118,438,593
Ensembl chr 8:109,530,641...109,558,354
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G |
Cenpf |
centromere protein F |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CENPF mRNA |
CTD |
PMID:37567420 |
|
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:101,184,127...101,229,669
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G |
Ces2h |
carboxylesterase 2H |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CES2H mRNA |
CTD |
PMID:37567420 |
|
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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G |
Cfap74 |
cilia and flagella associated protein 74 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CFAP74 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:171,252,907...171,328,351
Ensembl chr 5:165,979,805...166,046,071
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G |
Cfap97d1 |
CFAP97 domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CFAP97D1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:86,933,585...86,944,566
Ensembl chr10:86,933,808...86,938,244
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G |
Cfd |
complement factor D |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CFD mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:9,813,150...9,815,053
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G |
Chgb |
chromogranin B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHGB mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
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G |
Chrdl2 |
chordin-like 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CHRDL2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CHRDL2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:154,343,201...154,370,651
Ensembl chr 1:154,343,201...154,370,640
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
increases expression |
EXP |
Fructose results in increased expression of CHRM2 mRNA; Fructose results in increased expression of CHRM2 protein |
CTD |
PMID:17707055 |
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NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,014,144...65,149,103
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G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
increases expression |
EXP |
Fructose results in increased expression of CHRM3 mRNA; Fructose results in increased expression of CHRM3 protein |
CTD |
PMID:17707055 |
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NCBI chr17:64,696,549...65,158,622
Ensembl chr17:60,005,202...60,467,278
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G |
Chrna2 |
cholinergic receptor nicotinic alpha 2 subunit |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHRNA2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr15:44,517,862...44,534,144
Ensembl chr15:40,342,317...40,358,601
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
increases phosphorylation multiple interactions |
EXP |
Fructose results in increased phosphorylation of CHUK protein Quercetin inhibits the reaction [Fructose results in increased phosphorylation of CHUK protein] |
CTD |
PMID:24491314 |
|
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065
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G |
Cidea |
cell death-inducing DFFA-like effector a |
multiple interactions decreases expression |
EXP |
[Ozone co-treated with Fructose] results in decreased expression of CIDEA mRNA; [Particulate Matter co-treated with Fructose] results in decreased expression of CIDEA mRNA; [Particulate Matter co-treated with Ozone co-treated with Fructose] results in decreased expression of CIDEA mRNA Fructose results in decreased expression of CIDEA mRNA |
CTD |
PMID:23968387 |
|
NCBI chr18:63,164,817...63,190,384
Ensembl chr18:60,894,874...60,920,481
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G |
Cimap1c |
ciliary microtubule associated protein 1C |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CIMAP1C mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:66,144,726...66,176,985
Ensembl chr 8:57,248,746...57,281,004
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G |
Ckap2 |
cytoskeleton associated protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CKAP2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr16:76,542,114...76,567,297
Ensembl chr16:69,839,630...69,864,913
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G |
Clec4a |
C-type lectin domain family 4, member A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CLEC4N mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:158,026,138...158,119,904
Ensembl chr 4:156,414,688...156,432,402
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G |
Clec4e |
C-type lectin domain family 4, member E |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLEC4E mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:156,607,614...156,612,767
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G |
Clhc1 |
clathrin heavy chain linker domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CLHC1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:103,288,116...103,328,725
Ensembl chr14:103,288,134...103,328,715
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G |
Clic6 |
chloride intracellular channel 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLIC6 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr11:45,223,715...45,266,261
Ensembl chr11:31,737,813...31,780,061
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G |
Clspn |
claspin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CLSPN mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:144,134,619...144,169,531
Ensembl chr 5:138,850,128...138,885,034
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G |
Clstn3 |
calsyntenin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLSTN3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:159,017,795...159,051,069
Ensembl chr 4:157,331,494...157,364,769
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G |
Cma1 |
chymase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CMA1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr15:33,387,351...33,390,133
Ensembl chr15:29,417,451...29,420,233
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G |
Cnr1 |
cannabinoid receptor 1 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of CNR1 mRNA [Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA] |
CTD |
PMID:18627777 PMID:31468622 |
|
NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099
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G |
Cntn4 |
contactin 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CNTN4 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090
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G |
Cntnap2 |
contactin associated protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CNTNAP2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:74,109,472...76,362,027
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G |
Cntnap5b |
contactin associated protein family member 5B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CNTNAP5A mRNA |
CTD |
PMID:37567420 |
|
NCBI chr13:17,863,367...18,766,983
Ensembl chr13:18,093,420...18,761,014
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G |
Col19a1 |
collagen type XIX alpha 1 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL19A1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 9:34,170,248...34,518,478
Ensembl chr 9:26,675,391...27,022,106
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
[Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in decreased expression of COL1A1 protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of COL1A1 mRNA; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of COL1A1 mRNA |
CTD |
PMID:37271273 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
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G |
Col27a1 |
collagen type XXVII alpha 1 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of COL27A1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:81,662,822...81,781,502
Ensembl chr 5:76,647,429...76,765,174
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G |
Col5a2 |
collagen type V alpha 2 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL5A2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:47,448,736...47,598,154
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G |
Col6a5 |
collagen type VI alpha 5 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A5 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL6A5 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:106,483,806...106,584,114
Ensembl chr 8:106,483,799...106,584,113
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G |
Col6a6 |
collagen type VI alpha 6 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A6 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL6A6 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:106,318,010...106,473,419
Ensembl chr 8:106,306,422...106,473,472
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G |
Col8a2 |
collagen type VIII alpha 2 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of COL8A2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:143,870,754...143,897,372
Ensembl chr 5:138,585,999...138,612,850
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G |
Coq9 |
coenzyme Q9 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of COQ9 protein |
CTD |
PMID:26930160 |
|
NCBI chr19:10,172,943...10,185,960
Ensembl chr19:10,166,951...10,179,949
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G |
Cox6a2 |
cytochrome c oxidase subunit 6A2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of COX6A2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:182,788,528...182,789,274
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G |
Cp |
ceruloplasmin |
multiple interactions |
EXP |
[Fructose co-treated with Copper deficiency] results in decreased activity of CP protein; Fructose promotes the reaction [Copper deficiency results in decreased expression of CP protein] |
CTD |
PMID:21781943 PMID:25813056 |
|
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075
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G |
Cpe |
carboxypeptidase E |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CPE mRNA |
CTD |
PMID:37567420 |
|
NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
EXP |
[Dietary Fats co-treated with Fructose] results in increased expression of CPT1A mRNA; [Fructose co-treated with Copper deficiency] results in decreased expression of CPT1A mRNA; [Fructose co-treated with Dietary Fats] results in decreased expression of CPT1A protein |
CTD |
PMID:19632207 PMID:25813056 PMID:32259528 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
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|
G |
Creb1 |
cAMP responsive element binding protein 1 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of CREB1 mRNA; Fructose results in increased expression of CREB1 protein rosiglitazone inhibits the reaction [Fructose results in increased expression of CREB1 mRNA]; rosiglitazone inhibits the reaction [Fructose results in increased expression of CREB1 protein] |
CTD |
PMID:19196556 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816
|
|
G |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CREB3L3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:9,273,320...9,281,755
Ensembl chr 7:8,622,614...8,631,048
|
|
G |
Crp |
C-reactive protein |
multiple interactions increases expression |
EXP ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of CRP mRNA; Curcumin inhibits the reaction [Fructose results in increased expression of CRP protein]; Metformin inhibits the reaction [Fructose results in increased expression of CRP protein]; resveratrol inhibits the reaction [Fructose results in increased expression of CRP protein] |
CTD |
PMID:19632207 PMID:25108154 PMID:26713546 PMID:31672515 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178
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|
G |
Crtac1 |
cartilage acidic protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CRTAC1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421
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G |
Cryaa |
crystallin, alpha A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CRYAA mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CRYAA mRNA |
CTD |
PMID:37567420 |
|
NCBI chr20:9,784,872...9,788,656
Ensembl chr20:9,783,605...9,787,349
|
|
G |
Crybg2 |
crystallin beta-gamma domain containing 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CRYBG2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:146,286,925...146,323,666
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G |
Cst3 |
cystatin C |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein] |
CTD |
PMID:30551545 |
|
NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:136,336,920...136,340,822
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G |
Cst6 |
cystatin E/M |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CST6 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:202,655,322...202,657,030
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
EXP |
Fructose results in decreased expression of and results in increased phosphorylation of CTNNB1 protein |
CTD |
PMID:36049592 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsw |
cathepsin W |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CTSW mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:212,201,904...212,208,028
Ensembl chr 1:202,772,572...202,775,964
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
Fructose results in increased expression of CX3CL1 mRNA |
CTD |
PMID:31655124 |
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NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CXCL10 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CXCL1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CXCL9 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
EXP |
[Dietary Fats co-treated with Fructose] results in increased expression of CYBB mRNA |
CTD |
PMID:19632207 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions increases expression |
EXP ISO |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of CYCS protein]; [Fructose co-treated with Dietary Fats] results in increased expression of CYCS protein; Plant Extracts inhibits the reaction [Fructose results in increased expression of CYCS protein] [Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] |
CTD |
PMID:32259528 PMID:32730863 PMID:33475235 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A1 mRNA |
CTD |
PMID:26102010 PMID:29416063 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA; alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:26102010 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA; [Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA]; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein] |
CTD |
PMID:26102010 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CYP27B1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:62,871,297...62,876,241
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CYP2B10 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 mRNA; [Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein; alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein]; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 mRNA]; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein] |
CTD |
PMID:26102010 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression increases expression multiple interactions |
ISO |
Fructose results in decreased expression of CYP2E1 protein Fructose results in increased expression of CYP2E1 protein [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of CYP2E1 mRNA; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of CYP2E1 protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of CYP2E1 mRNA; Ethanol promotes the reaction [Fructose results in increased expression of CYP2E1 protein] |
CTD |
PMID:26858005 PMID:28257781 PMID:37271273 |
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NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CYP3A13 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Fructose co-treated with Copper deficiency] results in decreased expression of CYP4A1 mRNA; gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of CYP4A1 mRNA] |
CTD |
PMID:25813056 |
|
NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CYP7B1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:100,502,791...100,669,698
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G |
Cysrt1 |
cysteine rich tail 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CYSRT1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:28,452,359...28,456,006
Ensembl chr 3:8,053,482...8,059,721
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DBP mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DBP mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:96,175,440...96,180,745
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G |
Dclk1 |
doublecortin-like kinase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DCLK1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:139,417,163...139,710,956
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G |
Ddias |
DNA damage-induced apoptosis suppressor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of DDIAS mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein] |
CTD |
PMID:34801538 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddt |
D-dopachrome tautomerase |
decreases expression multiple interactions |
EXP |
Fructose results in decreased expression of DDT protein [Fructose co-treated with bisphenol A] results in increased expression of DDT protein |
CTD |
PMID:26930160 |
|
NCBI chr20:12,883,025...12,886,121
Ensembl chr20:12,884,243...12,888,482
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G |
Defb24 |
defensin beta 24 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DEFB19 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:161,506,850...161,512,983
Ensembl chr 3:141,046,564...141,052,753
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G |
Dek |
DEK proto-oncogene |
multiple interactions |
ISO |
DEK protein results in decreased chemical synthesis of and results in decreased secretion of Fructose |
CTD |
PMID:28558019 |
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NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,580,843...17,602,808
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G |
Depp1 |
DEPP autophagy regulator 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of DEPP1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:151,583,105...151,585,455
Ensembl chr 4:149,910,779...149,914,542
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G |
Derl3 |
derlin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DERL3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,763,543...12,767,027
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G |
Deup1 |
deuterosome assembly protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of DEUP1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DEUP1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of DGAT1 mRNA |
CTD |
PMID:28123933 |
|
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[FGF21 gene mutant form results in increased susceptibility to Fructose] which results in decreased expression of DGAT2 mRNA |
CTD |
PMID:28123933 |
|
NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:153,454,080...153,484,428
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G |
Dhrs9 |
dehydrogenase/reductase 9 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DHRS9 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:54,147,803...54,220,241
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G |
Dhx58 |
DEXH-box helicase 58 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DHX58 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525
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G |
Diaph3 |
diaphanous-related formin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DIAPH3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr15:68,951,992...69,421,623
Ensembl chr15:62,543,375...63,012,975
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G |
Diras2 |
DIRAS family GTPase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of DIRAS2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr17:12,730,040...12,761,511
Ensembl chr17:12,725,149...12,761,663
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G |
Disc1 |
DISC1 scaffold protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of DISC1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of DISC1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr19:69,911,548...70,120,970
Ensembl chr19:53,014,616...53,219,778
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G |
Dld |
dihydrolipoamide dehydrogenase |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of DLD protein |
CTD |
PMID:26930160 |
|
NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
decreases expression |
EXP |
Fructose results in decreased expression of DLG4 protein |
CTD |
PMID:37121297 |
|
NCBI chr10:55,239,397...55,267,780
Ensembl chr10:54,739,470...54,767,153
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of DLK1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:128,410,316...128,417,522
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G |
Dnase1l3 |
deoxyribonuclease 1L3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DNASE1L3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr15:19,351,683...19,378,536
Ensembl chr15:16,922,335...16,948,317
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] [Tribulus extract co-treated with Fructose] results in decreased expression of DNM1L protein modified form |
CTD |
PMID:32730863 PMID:36214339 |
|
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:84,581,216...84,631,482
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G |
Dok7 |
docking protein 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DOK7 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:79,890,051...79,924,081
Ensembl chr14:75,666,744...75,699,386
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G |
Dpp4 |
dipeptidylpeptidase 4 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of DPP4 mRNA; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of DPP4 protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of DPP4 mRNA |
CTD |
PMID:37271273 |
|
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901
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G |
Dpp6 |
dipeptidyl peptidase like 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of DPP6 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
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G |
Dpt |
dermatopontin |
multiple interactions decreases expression |
EXP |
[Ozone co-treated with Fructose] results in decreased expression of DPT mRNA; [Particulate Matter co-treated with Fructose] results in decreased expression of DPT mRNA; Fructose affects the reaction [[Ozone co-treated with Particulate Matter] results in decreased expression of DPT mRNA] Fructose results in decreased expression of DPT mRNA |
CTD |
PMID:23968387 |
|
NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639
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G |
Dpysl2 |
dihydropyrimidinase-like 2 |
decreases expression |
EXP |
Fructose results in decreased expression of DPYSL2 protein |
CTD |
PMID:37121297 |
|
NCBI chr15:45,181,041...45,287,065
Ensembl chr15:41,005,551...41,111,829
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G |
Dscaml1 |
DS cell adhesion molecule-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of DSCAML1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of DUSP5 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:252,538,449...252,551,818
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G |
Ebln1 |
endogenous Bornavirus like nucleoprotein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV8-24 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:78,938,645...78,940,651
|
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of ECHS1 protein |
CTD |
PMID:26930160 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884
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G |
Edaradd |
EDAR associated via death domain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of EDARADD mRNA |
CTD |
PMID:37567420 |
|
NCBI chr17:92,850,791...92,894,808
Ensembl chr17:85,656,905...85,910,447
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G |
Edn1 |
endothelin 1 |
increases response to substance increases expression multiple interactions |
EXP |
Fructose results in increased susceptibility to EDN1 protein Fructose results in increased expression of EDN1 mRNA; Fructose results in increased expression of EDN1 protein modified form KLK1 protein inhibits the reaction [Fructose results in increased expression of EDN1 mRNA]; Metformin inhibits the reaction [Fructose results in increased expression of EDN1 protein]; resveratrol inhibits the reaction [Fructose results in increased expression of EDN1 protein] |
CTD |
PMID:9869011 PMID:11172478 PMID:14568997 PMID:25108154 |
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NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
multiple interactions increases expression |
EXP ISO |
KLK1 protein inhibits the reaction [Fructose results in increased expression of EDNRA mRNA] |
CTD |
PMID:9869011 PMID:14568997 PMID:31655124 |
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NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049
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G |
Eef1a2 |
eukaryotic translation elongation factor 1 alpha 2 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of EEF1A2 protein |
CTD |
PMID:26930160 |
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NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
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G |
Efhc1 |
EF-hand domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of EFHC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:30,872,238...30,910,703
Ensembl chr 9:23,375,840...23,414,283
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G |
Egf |
epidermal growth factor |
multiple interactions increases uptake |
EXP |
wortmannin inhibits the reaction [EGF protein results in increased uptake of Fructose] |
CTD |
PMID:15691865 |
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NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:218,219,415...218,302,064
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of EGR1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of EGR2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,051,277...21,055,562
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of EHHADH mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:92,746,409...92,779,647
Ensembl chr11:79,241,938...79,275,188
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of EIF2AK2 protein imoxin inhibits the reaction [Fructose results in increased expression of EIF2AK2 protein] |
CTD |
PMID:29430716 |
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NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
increases phosphorylation multiple interactions |
ISO EXP |
Fructose results in increased phosphorylation of EIF2AK3 protein [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein] Phenylbutyrates inhibits the reaction [Fructose results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:22698815 PMID:34801538 |
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NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO |
Fructose results in increased phosphorylation of EIF2S1 protein Phenylbutyrates inhibits the reaction [Fructose results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:22698815 |
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NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression |
ISO |
Fructose results in increased expression of ELOVL6 mRNA |
CTD |
PMID:15066988 |
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NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186
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G |
Emc1 |
ER membrane protein complex subunit 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of EMC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888
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G |
Enkur |
enkurin, TRPC channel interacting protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ENKUR mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:83,690,105...83,714,756
Ensembl chr17:83,690,797...83,714,408
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G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
decreases expression |
EXP |
Fructose results in decreased expression of ENTPD2 mRNA |
CTD |
PMID:15150374 |
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NCBI chr 3:28,611,722...28,617,237
Ensembl chr 3:8,213,663...8,226,866
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G |
Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ENTPD4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:51,040,665...51,068,450
Ensembl chr15:44,630,873...44,658,706
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G |
Epb42 |
erythrocyte membrane protein band 4.2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of EPB42 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:128,433,460...128,451,683
Ensembl chr 3:107,979,713...107,997,932
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G |
Epop |
elongin BC and polycomb repressive complex 2 associated protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of EPOP mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:83,120,767...83,122,287
Ensembl chr10:82,624,392...82,625,912
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G |
Eppk1 |
epiplakin 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of EPPK1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:107,817,693...107,831,159
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G |
Epsti1 |
epithelial stromal interaction 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of EPSTI1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:59,692,712...59,791,376
Ensembl chr15:53,284,216...53,382,191
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein] |
CTD |
PMID:34801538 |
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NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
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G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ERN2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions decreases expression |
EXP |
bisphenol A promotes the reaction [Fructose results in decreased expression of ESR1 protein]; Fructose promotes the reaction [bisphenol A results in decreased expression of ESR1 protein] |
CTD |
PMID:31661889 |
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NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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G |
Ezr |
ezrin |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of EZR protein |
CTD |
PMID:26930160 |
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NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:46,967,658...47,011,505
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G |
F13a1 |
coagulation factor XIII A1 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of F13A1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:28,021,197...28,197,960
Ensembl chr17:27,815,702...27,992,700
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G |
F3 |
coagulation factor III, tissue factor |
increases expression |
ISO |
Fructose results in increased expression of F3 mRNA |
CTD |
PMID:31655124 |
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NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668
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G |
F7 |
coagulation factor VII |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of F7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610
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G |
Fabp3 |
fatty acid binding protein 3 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of FABP3 protein |
CTD |
PMID:26930160 |
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NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:142,651,956...142,658,718
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of FABP4 protein |
CTD |
PMID:26930160 |
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NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578
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G |
Fadd |
Fas associated via death domain |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of FADD protein Plant Extracts inhibits the reaction [Fructose results in increased expression of FADD protein] |
CTD |
PMID:33475235 |
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NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653
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G |
Fam163a |
family with sequence similarity 163, member A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FAM163A mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:68,262,867...68,341,323
Ensembl chr13:68,262,872...68,341,049
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G |
Fam163b |
family with sequence similarity 163, member B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAM163B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:30,834,145...30,865,802
Ensembl chr 3:10,437,383...10,466,458
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G |
Fam167a |
family with sequence similarity 167, member A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAM167A mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:37,685,221...37,715,472
Ensembl chr15:37,700,919...37,715,469
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G |
Fam178b |
family with sequence similarity 178, member B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of FAM178B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:38,805,864...38,913,681
Ensembl chr 9:38,805,864...38,913,672
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G |
Fas |
Fas cell surface death receptor |
decreases expression multiple interactions increases expression |
ISO EXP |
Fructose results in decreased expression of FAS mRNA Plant Extracts inhibits the reaction [Fructose results in increased expression of FAS protein] |
CTD |
PMID:31655124 PMID:33475235 |
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NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
increases expression multiple interactions |
ISO |
Fructose results in increased expression of FASLG mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of FASL mRNA |
CTD |
PMID:31655124 PMID:37567420 |
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NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
multiple interactions increases expression increases activity |
EXP ISO |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; [Copper deficiency co-treated with Fructose] results in increased expression of FASN protein; [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]; [Fructose co-treated with Dietary Fats] results in increased expression of FASN protein; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of FASN mRNA; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; bisphenol A promotes the reaction [Fructose results in increased expression of FASN mRNA]; bisphenol A promotes the reaction [Fructose results in increased expression of FASN protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of FASN protein]; Fenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Resveratrol inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Rosiglitazone inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Tea inhibits the reaction [Fructose results in increased expression of FASN mRNA] [Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein] FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Phenylbutyrates inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Plant Preparations inhibits the reaction [Fructose results in increased expression of FASN protein]; SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of FASN mRNA] Fructose results in increased expression of FASN mRNA; Fructose results in increased expression of FASN protein Fructose results in increased activity of FASN protein |
CTD |
PMID:8759368 PMID:9566986 PMID:12065722 PMID:15066988 PMID:18346472 PMID:19053045 PMID:19193814 PMID:19196556 PMID:21781943 PMID:22698815 PMID:25813056 PMID:26973390 PMID:27531227 PMID:28123933 PMID:28257781 PMID:31661889 PMID:32259528 PMID:32730863 More...
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NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
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G |
Fat3 |
FAT atypical cadherin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FAT3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAT3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:20,972,840...21,555,679
Ensembl chr 8:12,694,019...13,273,135
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G |
Faxc |
failed axon connections homolog, metaxin like GST domain containing |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAXC mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446
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G |
Fbp1 |
fructose-bisphosphatase 1 |
increases activity increases expression multiple interactions |
EXP |
Fructose results in increased activity of FBP1 protein Fructose results in increased expression of FBP1 mRNA Vanadates inhibits the reaction [Fructose results in increased activity of FBP1 protein] |
CTD |
PMID:15150374 PMID:16920846 PMID:18346472 |
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NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,208,031...2,230,071
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G |
Fbxo47 |
F-box protein 47 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FBXO47 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:82,849,514...82,880,337
Ensembl chr10:82,849,730...82,879,538
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G |
Fbxo48 |
F-box protein 48 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FBXO48 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FBXO48 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314
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G |
Fcgr3a |
Fc gamma receptor 3A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of FCGR4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:85,782,636...85,792,656
Ensembl chr13:83,249,872...83,259,921
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G |
Fcrlb |
Fc receptor-like B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FCRLB mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:85,681,403...85,689,880
Ensembl chr13:83,149,751...83,155,957
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G |
Fen1 |
flap structure-specific endonuclease 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of FEN1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003
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G |
Fendrr |
FOXF1 adjacent non-coding developmental regulatory RNA |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FENDRR mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:66,035,910...66,061,466
Ensembl chr19:49,121,214...49,153,240
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G |
Ffar3 |
free fatty acid receptor 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FFAR3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FFAR3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions increases expression increases response to substance increases secretion |
ISO |
[FGF21 gene mutant form results in increased susceptibility to Fructose] which results in decreased abundance of Blood Glucose; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in decreased expression of APOB mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in decreased expression of DGAT2 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of CCL2 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of CCL3 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of CD68 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of DGAT1 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of MMP2 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of TGFB1 mRNA; [FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of TGFB2 mRNA; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACB mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of ALDOB mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of KHK mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of MLXIPL mRNA alternative form]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of MTTP mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of PKLR mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of SCD1 mRNA]; FGF21 gene mutant form inhibits the reaction [Fructose results in increased secretion of very low density lipoprotein triglyceride]; MLXIPL gene mutant form inhibits the reaction [Fructose results in increased expression of FGF21 mRNA]; MLXIPL gene mutant form inhibits the reaction [Fructose results in increased secretion of FGF21 protein] |
CTD |
PMID:28123933 |
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NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgg |
fibrinogen gamma chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FGG mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322
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G |
Fhad1 |
forkhead associated phosphopeptide binding domain 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FHAD1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:154,191,593...154,310,442
Ensembl chr 5:154,191,745...154,310,354
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G |
Fhl2 |
four and a half LIM domains 2 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of FHL2 protein |
CTD |
PMID:26930160 |
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NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:45,388,981...45,431,192
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] |
CTD |
PMID:32730863 |
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NCBI chr12:25,345,239...25,360,135
Ensembl chr12:19,708,558...19,723,377
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G |
Flg |
filaggrin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FLG mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:181,583,801...181,596,464
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G |
Fmo3 |
flavin containing dimethylaniline monoxygenase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FMO3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:77,838,899...77,868,869
Ensembl chr13:75,309,374...75,328,028
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
Dactinomycin inhibits the reaction [Fructose results in increased expression of FOS mRNA] |
CTD |
PMID:11123204 PMID:11557636 |
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NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxa3 |
forkhead box A3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of FOXA3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:78,662,431...78,672,155
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G |
Foxf2 |
forkhead box F2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FOXF2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:33,044,446...33,051,259
Ensembl chr17:32,836,777...32,842,176
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G |
Foxo1 |
forkhead box O1 |
multiple interactions increases expression |
EXP |
Fructose results in increased expression of and affects the localization of FOXO1 protein; Fructose results in increased expression of and results in increased phosphorylation of FOXO1 protein; Quercetin inhibits the reaction [Fructose results in increased expression of and affects the localization of FOXO1 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of FOXO1 protein]; Rosiglitazone inhibits the reaction [Fructose results in increased expression of FOXO1 mRNA] |
CTD |
PMID:19196556 PMID:23533474 |
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NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
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G |
Frmd3 |
FERM domain containing 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FRMD3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
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G |
Frmpd3 |
FERM and PDZ domain containing 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FRMPD3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr X:103,964,168...104,113,864
Ensembl chr X:104,043,194...104,111,968
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G |
Fsbp |
fibrinogen silencer binding protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FSBP mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:25,058,003...25,064,276
Ensembl chr 5:25,032,066...25,104,616
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein] |
CTD |
PMID:34656705 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
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G |
Fsip1 |
fibrous sheath interacting protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of FSIP1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167
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G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
EXP |
Fructose results in increased expression of FTH1 protein |
CTD |
PMID:26930160 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424
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G |
Fut1 |
fucosyltransferase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FUT1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
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G |
Fut2 |
fucosyltransferase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FUT2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FUT2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:105,256,013...105,276,828
Ensembl chr 1:96,119,371...96,140,360
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions increases expression |
EXP |
Rosiglitazone inhibits the reaction [Fructose results in increased expression of G6PC1 mRNA]; Rosiglitazone inhibits the reaction [Fructose results in increased expression of G6PC1 protein] Fructose results in increased expression of G6PC1 mRNA; Fructose results in increased expression of G6PC1 protein |
CTD |
PMID:14988444 PMID:15150374 PMID:16920846 PMID:18346472 PMID:18556366 PMID:19196556 More...
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NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases activity multiple interactions decreases expression |
EXP |
Fructose results in increased activity of G6PD protein Glutamine inhibits the reaction [Fructose results in decreased expression of G6PD protein] |
CTD |
PMID:18346472 PMID:31233715 |
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NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GABBR2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:60,947,526...61,288,104
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G |
Gabrp |
gamma-aminobutyric acid type A receptor subunit pi |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GABRP mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:18,647,243...18,673,806
Ensembl chr10:18,143,038...18,169,516
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G |
Gabrq |
gamma-aminobutyric acid type A receptor subunit theta |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GABRQ mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:155,737,838...155,755,225
Ensembl chr X:150,696,427...150,709,919
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G |
Galnt16 |
polypeptide N-acetylgalactosaminyltransferase 16 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GALNT16 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
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G |
Galnt2 |
polypeptide N-acetylgalactosaminyltransferase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GALNT2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
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G |
Galnt6 |
polypeptide N-acetylgalactosaminyltransferase 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GALNT6 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:131,789,836...131,828,077
Ensembl chr 7:131,789,839...131,819,661
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G |
Gap43 |
growth associated protein 43 |
decreases expression |
EXP |
Fructose results in decreased expression of GAP43 protein |
CTD |
PMID:37121297 |
|
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:58,376,371...58,470,045
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GAPDH mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235
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G |
Gbp2 |
guanylate binding protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571
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G |
Gbp4 |
guanylate binding protein 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP4 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:231,305,244...231,318,879
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G |
Gbp7 |
guanylate binding protein 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP7 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:233,948,774...233,970,532
Ensembl chr 2:231,275,640...231,297,278
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G |
Gc |
GC, vitamin D binding protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GC mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,632,135...18,667,567
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G |
Gcg |
glucagon |
multiple interactions |
EXP |
GCG protein affects the reaction [Fructose affects the degradation of PKLR mRNA] |
CTD |
PMID:2414297 |
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NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:47,113,914...47,122,929
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G |
Gck |
glucokinase |
increases activity multiple interactions |
EXP ISO |
Fructose results in increased activity of GCK protein [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of GCK mRNA |
CTD |
PMID:20470786 PMID:37567420 |
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NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995
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G |
Gckr |
glucokinase regulator |
increases expression |
EXP |
Fructose results in increased expression of GCKR mRNA |
CTD |
PMID:18346472 |
|
NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:25,045,100...25,075,654
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G |
Gcsam |
germinal center-associated, signaling and motility |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GCSAM mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:68,658,350...68,669,598
Ensembl chr11:55,196,712...55,206,992
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G |
Gdap1l1 |
ganglioside-induced differentiation-associated protein 1-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GDAP1L1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:172,529,523...172,549,128
Ensembl chr 3:152,110,253...152,128,711
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G |
Gdf7 |
growth differentiation factor 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GDF7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:31,171,495...31,182,484
Ensembl chr 6:31,178,119...31,182,447
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G |
Ghrhr |
growth hormone releasing hormone receptor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GHRHR mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776
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G |
Ghrl |
ghrelin and obestatin prepropeptide |
increases expression |
EXP |
Fructose results in increased expression of GHRL protein |
CTD |
PMID:18627777 |
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NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:146,865,712...146,869,621
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Fructose] results in decreased expression of GJA1 protein; Atorvastatin promotes the reaction [dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of GJA1 protein]]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of GJA1 protein] |
CTD |
PMID:34939712 |
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NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582
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G |
Gli2 |
GLI family zinc finger 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GLI2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574
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G |
Glipr1 |
GLI pathogenesis-related 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GLIPR1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:49,373,579...49,399,190
Ensembl chr 7:47,487,345...47,498,429
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions |
EXP |
[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] |
CTD |
PMID:31468622 |
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NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,972,004...9,010,241
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G |
Glt8d2 |
glycosyltransferase 8 domain containing 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of GLT8D2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:21,029,534...21,081,081
Ensembl chr 7:21,029,525...21,081,080
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G |
Glul |
glutamate-ammonia ligase |
decreases expression multiple interactions |
EXP |
Fructose results in decreased expression of GLUL protein Allopurinol inhibits the reaction [Fructose results in decreased expression of GLUL protein]; Quercetin inhibits the reaction [Fructose results in decreased expression of GLUL protein] |
CTD |
PMID:24491314 |
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NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108
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G |
Gna15 |
G protein subunit alpha 15 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GNA15 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,184,861...8,205,508
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G |
Gnat2 |
G protein subunit alpha transducin 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GNAT2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866
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G |
Gnat3 |
G protein subunit alpha transducin 3 |
affects response to substance |
ISO |
GNAT3 protein affects the susceptibility to Fructose |
CTD |
PMID:16740645 |
|
NCBI chr 4:18,054,551...18,104,332
Ensembl chr 4:17,162,490...17,212,283
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G |
Gnmt |
glycine N-methyltransferase |
multiple interactions |
ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of GNMT mRNA |
CTD |
PMID:29416063 |
|
NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:14,254,675...14,258,434
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G |
Golt1a |
golgi transport 1A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GOLT1A mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:44,760,356...44,773,123
Ensembl chr13:44,760,380...44,773,122
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G |
Gp5 |
glycoprotein V (platelet) |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GP5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
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G |
Gp6 |
glycoprotein VI |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GP6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:69,465,789...69,491,326
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G |
Gp9 |
glycoprotein IX (platelet) |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GP9 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:121,792,842...121,794,452
Ensembl chr 4:120,235,421...120,237,110
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
multiple interactions increases expression |
EXP |
[Folic Acid affects the susceptibility to Fructose] which affects the expression of GPAM mRNA; Atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA] |
CTD |
PMID:18346472 PMID:19053045 PMID:31612177 |
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NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:254,106,331...254,142,639
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G |
Gpc5 |
glypican 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of GPC5 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
increases expression |
EXP |
Fructose results in increased expression of GPD1 mRNA |
CTD |
PMID:36049592 |
|
NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:130,844,138...130,851,529
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G |
Gpha2 |
glycoprotein hormone subunit alpha 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of GPHA2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:203,525,952...203,527,271
Ensembl chr 1:203,526,122...203,527,270
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G |
Gpld1 |
glycosylphosphatidylinositol specific phospholipase D1 |
increases expression |
ISO |
Fructose results in increased expression of GPLD1 protein |
CTD |
PMID:16219662 |
|
NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,084,617...40,126,939
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G |
Gpnmb |
glycoprotein nmb |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GPNMB mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:78,010,197...78,049,367
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G |
Gpr151 |
G protein-coupled receptor 151 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GPR151 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:34,568,907...34,570,301
Ensembl chr18:34,568,907...34,570,301
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G |
Gpr171 |
G protein-coupled receptor 171 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GPR171 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:143,360,402...143,365,494
Ensembl chr 2:143,359,564...143,366,698
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G |
Gpr85 |
G protein-coupled receptor 85 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GPR85 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566
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G |
Gpr87 |
G protein-coupled receptor 87 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GPR87 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:145,589,630...145,608,094
Ensembl chr 2:143,439,735...143,458,190
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G |
Gprin1 |
G protein-regulated inducer of neurite outgrowth 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of GPRIN1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:9,869,009...9,881,958
Ensembl chr17:9,863,571...9,876,915
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G |
Gpt |
glutamic--pyruvic transaminase |
increases activity multiple interactions |
ISO EXP |
Fructose results in increased activity of GPT protein [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; [Fructose co-treated with Dietary Fats] results in increased expression of GPT protein; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of GPT protein] [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of GPT protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of GPT protein; [Fructose co-treated with Ethanol] results in increased expression of GPT protein; Plant Preparations inhibits the reaction [Fructose results in increased activity of GPT protein] |
CTD |
PMID:26858005 PMID:27531227 PMID:32259528 PMID:33118400 PMID:37271273 |
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NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
decreases expression |
EXP |
Fructose results in decreased expression of GPX1 mRNA |
CTD |
PMID:16815490 PMID:20470786 |
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NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression |
EXP |
Fructose results in decreased expression of GPX4 protein |
CTD |
PMID:21781943 |
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NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982
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G |
Grap2 |
GRB2-related adaptor protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GRAP2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:113,997,356...114,071,073
Ensembl chr 7:112,117,142...112,190,877
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GREM1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:100,512,313...100,524,082
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G |
Grem2 |
gremlin 2, DAN family BMP antagonist |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of GREM2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:89,310,897...89,403,856
Ensembl chr13:86,778,500...86,871,615
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP |
Fructose results in increased expression of and results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:36049592 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
increases activity |
EXP |
Fructose results in increased activity of GSR protein |
CTD |
PMID:17710547 |
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NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
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G |
Gucy2e |
guanylate cyclase 2E |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GUCY2E mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:54,453,753...54,478,639
Ensembl chr10:53,959,010...53,974,067
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G |
Gzmb |
granzyme B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GZMB mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:34,459,007...34,462,469
Ensembl chr15:30,173,603...30,346,814
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G |
H2ax |
H2A.X variant histone |
multiple interactions |
ISO |
[Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of H2AX mRNA; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of H2AX mRNA |
CTD |
PMID:37271273 |
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NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions |
EXP ISO |
[Fructose co-treated with Copper deficiency] results in decreased expression of HAMP protein [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HAMP mRNA |
CTD |
PMID:25813056 PMID:37567420 |
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NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HAPLN1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:20,631,640...20,693,777
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP ISO |
[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]] [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of HAVCR1 mRNA |
CTD |
PMID:30551545 PMID:37567420 |
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NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698
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G |
Hbb |
hemoglobin subunit beta |
multiple interactions |
EXP |
Fructose promotes the reaction [Glucose binds to HBB protein]; geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]]; Pioglitazone inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] |
CTD |
PMID:25679220 |
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NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012
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G |
Hcrt |
hypocretin neuropeptide precursor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of HCRT mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210
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G |
Hdac5 |
histone deacetylase 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein] |
CTD |
PMID:34656705 |
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NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,152,978...87,188,235
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G |
Hdc |
histidine decarboxylase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of HDC mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:113,847,260...113,865,341
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G |
Hhipl1 |
HHIP-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HHIPL1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:127,219,616...127,243,839
Ensembl chr 6:127,220,014...127,242,564
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G |
Hipk4 |
homeodomain interacting protein kinase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of HIPK4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:91,938,308...91,948,680
Ensembl chr 1:82,810,708...82,821,077
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G |
Hk3 |
hexokinase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of HK3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,599,865...9,614,863
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions increases expression |
EXP |
[6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased activity of SIRT1 protein] inhibits the reaction [Fructose results in increased expression of HMGCR mRNA]; [Niacinamide results in decreased activity of SIRT1 protein] inhibits the reaction [Fructose results in increased expression of HMGCR mRNA]; Rotenone inhibits the reaction [Fructose results in increased expression of HMGCR mRNA]; Tea inhibits the reaction [Fructose results in increased expression of HMGCR mRNA] |
CTD |
PMID:19193814 PMID:21212096 |
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NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
multiple interactions |
EXP |
[Fructose co-treated with Copper deficiency] results in decreased expression of HMGCS2 mRNA; gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of HMGCS2 mRNA] |
CTD |
PMID:25813056 |
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NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:185,875,616...185,902,130
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G |
Hmmr |
hyaluronan-mediated motility receptor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of HMMR mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
EXP ISO |
[Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; [Curcumin co-treated with Fructose] results in increased expression of HMOX1 protein; [Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein; [Hemin co-treated with Fructose] results in increased expression of HMOX1 protein; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of HMOX1 protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of HMOX1 protein] [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of HMOX1 mRNA Fructose results in increased expression of HMOX1 mRNA |
CTD |
PMID:24508943 PMID:25268984 PMID:28257781 PMID:31655124 PMID:32259528 PMID:37567420 More...
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
multiple interactions decreases expression |
ISO EXP |
Cerulenin inhibits the reaction [Fructose results in decreased expression of HNF4A mRNA] Fructose results in decreased expression of HNF4A mRNA; Fructose results in decreased expression of HNF4A protein Berberine inhibits the reaction [Fructose results in decreased expression of HNF4A mRNA]; Berberine inhibits the reaction [Fructose results in decreased expression of HNF4A protein]; rosiglitazone inhibits the reaction [Fructose results in decreased expression of HNF4A mRNA] |
CTD |
PMID:17992261 PMID:18563319 PMID:19196556 |
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NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
multiple interactions decreases expression |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of HNRNPA2B1 protein Fructose results in decreased expression of HNRNPA2B1 protein |
CTD |
PMID:26930160 |
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NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of HNRNPA3 protein |
CTD |
PMID:26930160 |
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NCBI chr 3:80,984,470...80,999,413
Ensembl chr 3:60,578,673...60,588,306
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G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of HNRNPK protein |
CTD |
PMID:26930160 |
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NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,262,998...6,274,997
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G |
Hoxa2 |
homeobox A2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of HOXA2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:82,593,389...82,597,589
Ensembl chr 4:81,262,768...81,265,044
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G |
Hoxc9 |
homeobox C9 |
multiple interactions decreases expression |
EXP |
[Ozone co-treated with Fructose] results in decreased expression of HOXC9 mRNA; [Particulate Matter co-treated with Ozone co-treated with Fructose] results in decreased expression of HOXC9 mRNA; Fructose affects the reaction [Particulate Matter results in decreased expression of HOXC9 mRNA] Fructose results in decreased expression of HOXC9 mRNA |
CTD |
PMID:23968387 |
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NCBI chr 7:135,997,292...135,999,969
Ensembl chr 7:134,118,817...134,121,492
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G |
Hp |
haptoglobin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of HP mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
decreases expression |
ISO |
Fructose results in decreased expression of HPRT1 mRNA |
CTD |
PMID:31655124 |
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NCBI chr X:137,655,744...137,687,718
Ensembl chr X:132,736,096...132,768,154
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G |
Hrg |
histidine-rich glycoprotein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of HRG mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:91,559,087...91,573,982
Ensembl chr11:78,054,498...78,069,389
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G |
Hrh1 |
histamine receptor H 1 |
decreases expression |
EXP |
Fructose results in decreased expression of HRH1 mRNA |
CTD |
PMID:36049592 |
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NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:147,645,995...147,647,455
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G |
Hs6st2 |
heparan sulfate 6-O-sulfotransferase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of HS6ST2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:130,966,547...131,261,629
Ensembl chr X:130,968,385...131,261,492
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G |
Hsf2bp |
heat shock transcription factor 2 binding protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of HSF2BP mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression |
EXP |
Fructose results in increased expression of HSPA1B mRNA |
CTD |
PMID:15150374 |
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NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of HSPA1L mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,848,843...3,855,571
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
ISO EXP |
Fructose results in increased expression of HSPA5 mRNA; Fructose results in increased expression of HSPA5 protein [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein] Phenylbutyrates inhibits the reaction [Fructose results in increased expression of HSPA5 protein] |
CTD |
PMID:22698815 PMID:34801538 |
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions increases expression |
EXP |
Amlodipine inhibits the reaction [Fructose results in increased expression of HSPD1 protein]; rosiglitazone inhibits the reaction [Fructose results in increased expression of HSPD1 protein] |
CTD |
PMID:18948349 PMID:26930160 |
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NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of HSPE1 protein |
CTD |
PMID:26930160 |
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NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:56,589,789...56,593,089
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G |
Htra3 |
HtrA serine peptidase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of HTRA3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:79,293,535...79,321,936
Ensembl chr14:75,068,917...75,097,315
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G |
Hyal4 |
hyaluronidase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of HYAL4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
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G |
Hydin |
Hydin, axonemal central pair apparatus protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of HYDIN mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:55,146,382...55,492,660
Ensembl chr19:38,236,464...38,583,264
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO EXP |
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Fructose results in increased expression of ICAM1 protein]; Adenosine Triphosphate inhibits the reaction [Fructose results in increased expression of ICAM1 protein] Metformin inhibits the reaction [Fructose results in increased expression of ICAM1 protein modified form]; resveratrol inhibits the reaction [Fructose results in increased expression of ICAM1 protein modified form] Fructose results in increased expression of ICAM1 mRNA; Fructose results in increased expression of ICAM1 protein |
CTD |
PMID:18508964 PMID:25108154 |
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NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
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G |
Idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
decreases expression |
EXP |
Fructose results in decreased expression of IDH3B protein |
CTD |
PMID:26930160 |
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NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
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G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of IDI1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:66,539,761...66,547,524
Ensembl chr17:61,629,594...61,637,357
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G |
Ifi27l2a |
interferon, alpha-inducible protein 27 like 2A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFI27L2A mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:122,598,872...122,600,360
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G |
Ifit1 |
interferon-induced protein with tetratricopeptide repeats 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFIT1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:241,565,197...241,567,262
Ensembl chr 1:232,127,170...232,154,435
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFIT2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:232,102,570...232,108,635
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFIT3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:232,114,166...232,119,307
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G |
Igf1r |
insulin-like growth factor 1 receptor |
increases expression |
EXP |
Fructose results in increased expression of IGF1R protein |
CTD |
PMID:30480462 |
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NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777
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G |
Igf2bp1 |
insulin-like growth factor 2 mRNA binding protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of IGF2BP1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:81,405,021...81,447,814
Ensembl chr10:80,908,076...80,951,129
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions |
EXP |
[Fructose co-treated with Ozone co-treated with Particulate Matter] results in decreased expression of IGFBP3 mRNA; [Fructose co-treated with Ozone] results in decreased expression of IGFBP3 mRNA; [Particulate Matter co-treated with Fructose] results in decreased expression of IGFBP3 mRNA; Fructose affects the reaction [Particulate Matter results in decreased expression of IGFBP3 mRNA] |
CTD |
PMID:23968387 |
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NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083
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G |
Igfn1 |
immunoglobulin-like and fibronectin type III domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGFN1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:47,395,618...47,427,506
Ensembl chr13:47,395,595...47,437,879
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G |
Igkvl-ps13 |
immunoglobulin kappa variable like, pseudogene 13 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of IGKV1-133 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:96,968,574...96,969,477
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
increases phosphorylation multiple interactions |
EXP |
Fructose results in increased phosphorylation of IKBKB protein Allopurinol inhibits the reaction [Fructose results in increased phosphorylation of IKBKB protein]; Quercetin inhibits the reaction [Fructose results in increased phosphorylation of IKBKB protein] |
CTD |
PMID:24491314 |
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NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
multiple interactions decreases expression |
EXP |
[Fructose co-treated with Ozone co-treated with Particulate Matter] results in decreased expression of IL10 mRNA; Fructose affects the reaction [Ozone results in decreased expression of IL10 mRNA]; Fructose affects the reaction [Particulate Matter results in decreased expression of IL10 mRNA] Fructose results in decreased expression of IL10 mRNA |
CTD |
PMID:23968387 PMID:30480462 |
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NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IL12B mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of IL12RB2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:96,426,842...96,515,289
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
EXP |
Fructose promotes the reaction [bisphenol A results in increased expression of IL17A protein] Fructose results in increased expression of IL17A protein |
CTD |
PMID:31661889 |
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NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
multiple interactions increases expression |
EXP |
Allopurinol inhibits the reaction [Fructose results in increased expression of IL18 protein]; Felodipine inhibits the reaction [Fructose results in increased expression of IL18 mRNA]; Felodipine inhibits the reaction [Fructose results in increased expression of IL18 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of IL18 protein]; Rutin inhibits the reaction [Fructose results in increased expression of IL18 protein] Fructose results in increased expression of IL18 mRNA; Fructose results in increased expression of IL18 protein |
CTD |
PMID:18504504 PMID:22426011 |
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NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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G |
Il18rap |
interleukin 18 receptor accessory protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IL18RAP mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of IL18RAP mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:42,768,220...42,800,959
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G |
Il1b |
interleukin 1 beta |
increases expression increases secretion multiple interactions |
EXP ISO |
Fructose results in increased expression of IL1B protein Fructose results in increased secretion of IL1B protein [Fructose co-treated with Ethanol] results in increased expression of IL1B mRNA [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of IL1B mRNA; Allopurinol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of IL1B protein]; PTMA protein inhibits the reaction [Fructose results in increased expression of IL1B protein]; Quercetin inhibits the reaction [Fructose results in increased expression of IL1B protein]; Rutin inhibits the reaction [Fructose results in increased expression of IL1B protein]; tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of IL1B protein] |
CTD |
PMID:15885234 PMID:22426011 PMID:24491314 PMID:25679220 PMID:25813056 PMID:26358169 PMID:26858005 PMID:30480462 PMID:31005848 PMID:34939712 More...
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of IL1RN mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
increases expression |
EXP |
Fructose results in increased expression of IL2 protein |
CTD |
PMID:15885234 |
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NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
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G |
Il27 |
interleukin 27 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IL27 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:181,173,372...181,178,582
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G |
Il31ra |
interleukin 31 receptor A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of IL31RA mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:45,851,073...45,922,300
Ensembl chr 2:44,122,624...44,183,767
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression increases expression |
EXP ISO |
[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of IL6 mRNA; Allopurinol inhibits the reaction [Fructose results in increased expression of IL6 protein]; galangin inhibits the reaction [Fructose results in increased expression of IL6 protein]; Genistein inhibits the reaction [Fructose results in increased expression of IL6 protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL6 protein]; Metformin inhibits the reaction [Fructose results in increased expression of IL6 protein]; PTMA protein inhibits the reaction [Fructose results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [Fructose results in increased expression of IL6 protein]; Rutin inhibits the reaction [Fructose results in increased expression of IL6 protein]; tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of IL6 protein] [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of IL6 protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of IL6 protein Fructose results in decreased expression of IL6 mRNA; Fructose results in decreased expression of IL6 protein |
CTD |
PMID:15885234 PMID:21704028 PMID:21708140 PMID:22426011 PMID:25108154 PMID:25813056 PMID:26358169 PMID:27531227 PMID:30480462 PMID:31005848 PMID:31672515 PMID:37271273 More...
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
increases expression increases secretion multiple interactions decreases expression |
EXP ISO |
Fructose results in increased expression of INS1 mRNA; Fructose results in increased expression of INS1 protein Fructose results in increased secretion of INS1 protein Ethanol inhibits the reaction [Fructose results in increased expression of INS1 protein]; Fructose inhibits the reaction [Ethanol results in increased expression of INS1 protein] [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein; [Dietary Fats co-treated with Fructose] results in increased secretion of INS1 protein; [Fructose co-treated with Dietary Fats] results in increased expression of INS1 protein; [Fructose co-treated with Propylthiouracil] results in increased expression of INS1 protein; [Streptozocin co-treated with Fructose] results in increased expression of INS1 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of INS1 protein]; Acetylcysteine inhibits the reaction [Fructose results in increased expression of INS1 protein]; Allopurinol inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of INS1 protein]; Allopurinol inhibits the reaction [Fructose results in increased expression of INS1 protein]; betanin inhibits the reaction [Fructose results in increased expression of INS1 protein]; bisphenol A diglycidyl ether inhibits the reaction [chrysin inhibits the reaction [Fructose results in increased expression of INS1 protein]]; Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased secretion of INS1 protein]; caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein]; chrysin inhibits the reaction [Fructose results in increased expression of INS1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein]; Fatty Acids, Omega-3 inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased secretion of INS1 protein]; Fenofibrate inhibits the reaction [Fructose results in increased secretion of INS1 protein]; Fructose promotes the reaction [bisphenol A results in increased expression of INS1 protein]; Genistein inhibits the reaction [Fructose results in increased expression of INS1 protein]; iodopravadoline inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of INS1 protein]]; Luteolin inhibits the reaction [Fructose results in increased expression of INS1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased secretion of INS1 protein]; Metformin inhibits the reaction [Fructose results in increased secretion of INS1 protein]; Oleanolic Acid inhibits the reaction [Fructose results in increased expression of INS1 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of INS1 mRNA]; Quercetin inhibits the reaction [Fructose results in increased expression of INS1 protein]; Quercetin inhibits the reaction [Fructose results in increased secretion of INS1 protein]; Resveratrol inhibits the reaction [Fructose results in increased expression of INS1 protein]; royal jelly inhibits the reaction [Fructose results in increased expression of INS1 protein]; Rutin inhibits the reaction [Fructose results in increased expression of INS1 protein] Fructose results in decreased expression of INS1 protein |
CTD |
PMID:3553468 PMID:15680273 PMID:17587757 PMID:18981581 PMID:19605544 PMID:20470786 PMID:21704028 PMID:21781943 PMID:22426011 PMID:22627169 PMID:23533474 PMID:24704288 PMID:25169908 PMID:25559852 PMID:25882089 PMID:26488877 PMID:26858005 PMID:26973390 PMID:30256492 PMID:30343038 PMID:31661889 PMID:32259528 PMID:34656705 PMID:34939712 PMID:36049592 More...
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
decreases response to substance increases secretion increases expression multiple interactions |
ISO EXP |
Fructose results in decreased susceptibility to INS protein Fructose results in increased secretion of INS protein Fructose results in increased expression of INS protein; Fructose results in increased expression of INS2 mRNA Curcumin inhibits the reaction [Fructose results in increased expression of INS protein]; Hemin inhibits the reaction [Fructose results in increased expression of INS protein]; INS protein inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA]; Quercetin inhibits the reaction [Fructose results in increased expression of INS2 mRNA] |
CTD |
PMID:12010179 PMID:18360027 PMID:23533474 PMID:25268984 PMID:26713546 |
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NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775
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G |
Insig1 |
insulin induced gene 1 |
decreases expression increases expression multiple interactions |
ISO |
Fructose results in decreased expression of INSIG1 protein Fructose results in increased expression of INSIG1 mRNA Phenylbutyrates inhibits the reaction [Fructose results in decreased expression of INSIG1 protein] |
CTD |
PMID:22698815 |
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NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952
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G |
Insig2 |
insulin induced gene 2 |
increases expression |
ISO |
Fructose results in increased expression of INSIG2 mRNA |
CTD |
PMID:22698815 |
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NCBI chr13:35,025,160...35,052,937
Ensembl chr13:32,473,742...32,494,923
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G |
Insr |
insulin receptor |
decreases expression decreases phosphorylation multiple interactions |
EXP |
Fructose results in decreased expression of INSR mRNA; Fructose results in decreased expression of INSR protein Fructose results in decreased phosphorylation of INSR protein [Fructose co-treated with Oleanolic Acid] results in increased expression of INSR mRNA; [Fructose co-treated with Sodium Chloride, Dietary deficiency] results in decreased expression of INSR mRNA; [Fructose co-treated with Sodium Chloride, Dietary deficiency] results in decreased expression of INSR protein; Allopurinol inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein] |
CTD |
PMID:14573337 PMID:14633139 PMID:22426011 PMID:24491314 PMID:24704288 |
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NCBI chr12:5,991,135...6,129,275
Ensembl chr12:1,197,100...1,330,883
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G |
Ip6k3 |
inositol hexakisphosphate kinase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of IP6K3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:5,225,706...5,247,293
Ensembl chr20:5,224,120...5,245,428
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IRF1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166
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G |
Irf3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
[Fructose co-treated with Ethanol] results in increased expression of IRF3 protein; Fructose promotes the reaction [Ethanol results in increased expression of IRF3 mRNA] |
CTD |
PMID:26858005 |
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NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935
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G |
Irf7 |
interferon regulatory factor 7 |
multiple interactions increases expression |
ISO |
[Fructose co-treated with Ethanol] results in increased expression of IRF7 protein; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IRF7 mRNA Fructose results in increased expression of IRF7 protein |
CTD |
PMID:26858005 PMID:37567420 |
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NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832
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G |
Irgm |
immunity-related GTPase M |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IRGM1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578
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G |
Irs1 |
insulin receptor substrate 1 |
decreases expression increases phosphorylation decreases phosphorylation multiple interactions affects phosphorylation |
EXP ISO |
Fructose results in decreased expression of IRS1 mRNA; Fructose results in decreased expression of IRS1 protein Fructose results in increased phosphorylation of IRS1 protein Fructose results in decreased phosphorylation of IRS1 protein [Fructose co-treated with Oleanolic Acid] results in increased expression of IRS1 mRNA; [Fructose co-treated with Oleanolic Acid] results in increased expression of IRS1 protein; [Fructose co-treated with resveratrol] results in increased expression of IRS1 mRNA; Allopurinol inhibits the reaction [Fructose results in decreased phosphorylation of IRS1 protein]; Curcumin inhibits the reaction [Fructose affects the phosphorylation of IRS1 protein]; NOS3 protein inhibits the reaction [Fructose results in decreased expression of IRS1 protein]; Oleanolic Acid inhibits the reaction [Fructose results in increased phosphorylation of IRS1 protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of IRS1 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of IRS1 protein] |
CTD |
PMID:19008412 PMID:19165636 PMID:22426011 PMID:24704288 PMID:26488877 PMID:26713546 PMID:31672515 More...
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NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122
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G |
Irs2 |
insulin receptor substrate 2 |
decreases expression multiple interactions |
EXP |
Fructose results in decreased expression of IRS2 mRNA; Fructose results in decreased expression of IRS2 protein NOS3 protein inhibits the reaction [Fructose results in decreased expression of IRS2 protein]; resveratrol inhibits the reaction [Fructose results in decreased expression of IRS2 mRNA] |
CTD |
PMID:19008412 PMID:19165636 PMID:26488877 |
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NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482
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G |
Islr2 |
immunoglobulin superfamily containing leucine-rich repeat 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ISLR2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:67,504,042...67,512,125
Ensembl chr 8:58,608,709...58,614,650
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G |
Ism2 |
isthmin 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ISM2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ISM2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
ISO |
Fructose results in decreased expression of ITGB1 mRNA |
CTD |
PMID:31655124 |
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NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195
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G |
Itih2 |
inter-alpha-trypsin inhibitor heavy chain 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ITIH2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:73,285,281...73,321,555
Ensembl chr17:68,375,567...68,411,841
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G |
Itih3 |
inter-alpha trypsin inhibitor, heavy chain 3 |
decreases expression |
EXP |
Fructose results in decreased expression of ITIH3 protein |
CTD |
PMID:26930160 |
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NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
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G |
Izumo1 |
izumo sperm-oocyte fusion 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of IZUMO1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:96,090,817...96,096,893
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G |
Jak2 |
Janus kinase 2 |
decreases phosphorylation multiple interactions |
EXP |
Fructose results in decreased phosphorylation of JAK2 protein Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] |
CTD |
PMID:22426011 |
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NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
Dactinomycin inhibits the reaction [Fructose results in increased expression of JUN mRNA] |
CTD |
PMID:11123204 PMID:11557636 |
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NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
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G |
Jup |
junction plakoglobin |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of JUP protein |
CTD |
PMID:26930160 |
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NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,300,440...85,327,057
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G |
Kcng1 |
potassium voltage-gated channel modifier subfamily G member 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of KCNG1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
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G |
Kcng3 |
potassium voltage-gated channel modifier subfamily G member 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of KCNG3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:11,051,311...11,099,264
Ensembl chr 6:11,051,134...11,099,264
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G |
Kcnh1 |
potassium voltage-gated channel subfamily H member 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of KCNH1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of KCNH1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:106,253,101...106,555,712
Ensembl chr13:103,722,245...104,024,740
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G |
Kcnh6 |
potassium voltage-gated channel subfamily H member 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of KCNH6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:91,449,025...91,471,012
Ensembl chr10:90,949,846...90,970,701
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G |
Kcnip2 |
potassium voltage-gated channel interacting protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of KCNIP2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:244,641,150...244,664,874
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G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KCNMA1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:351,065...1,057,117
Ensembl chr15:302,214...1,001,198
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G |
Kcnmb3 |
potassium calcium-activated channel subfamily M regulatory beta subunit 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of KCNMB3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:115,255,788...115,270,142
Ensembl chr 2:115,253,761...115,270,142
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G |
Kctd8 |
potassium channel tetramerization domain containing 8 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of KCTD8 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:38,773,274...39,018,182
Ensembl chr14:38,773,634...39,017,554
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G |
Kdr |
kinase insert domain receptor |
multiple interactions |
EXP |
[bisphenol A co-treated with Fructose] results in increased expression of KDR mRNA |
CTD |
PMID:27622962 |
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NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018
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G |
Khk |
ketohexokinase |
multiple interactions increases expression |
ISO EXP |
KHK protein promotes the reaction [Fructose results in decreased abundance of Adenosine Triphosphate]; KHK protein promotes the reaction [Fructose results in increased abundance of Reactive Oxygen Species]; KHK protein promotes the reaction [Fructose results in increased secretion of CCL2 protein] Atorvastatin inhibits the reaction [Fructose results in increased expression of KHK protein] Fructose results in increased expression of KHK mRNA; Fructose results in increased expression of KHK protein FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of KHK mRNA]; Fructose results in increased expression of and results in increased activity of KHK protein |
CTD |
PMID:15066988 PMID:18346472 PMID:18395287 PMID:19158351 PMID:21122807 PMID:26858005 PMID:28123933 More...
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NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:25,445,300...25,455,717
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G |
Kif19 |
kinesin family member 19 |
increases expression |
EXP |
Fructose results in increased expression of KIF19 mRNA |
CTD |
PMID:37121297 |
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NCBI chr10:99,800,185...99,826,546
Ensembl chr10:99,799,400...99,826,546
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G |
Kif19b |
kinesin family member 19B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of KIF19B mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:14,144,163...14,196,259
Ensembl chr12:14,144,118...14,193,648
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G |
Kif20b |
kinesin family member 20B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of KIF20B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
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G |
Kif27 |
kinesin family member 27 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of KIF27 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:6,299,544...6,375,106
Ensembl chr17:6,299,569...6,369,768
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G |
Kif4a |
kinesin family member 4A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of KIF4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:69,761,803...69,864,335
Ensembl chr X:65,721,779...65,824,139
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G |
Klk1 |
kallikrein 1 |
multiple interactions |
EXP |
KLK1 protein inhibits the reaction [Fructose results in increased expression of AGTR1B mRNA]; KLK1 protein inhibits the reaction [Fructose results in increased expression of EDN1 mRNA]; KLK1 protein inhibits the reaction [Fructose results in increased expression of EDNRA mRNA] |
CTD |
PMID:14568997 |
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NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:94,642,687...94,646,754
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G |
Klrd1 |
killer cell lectin like receptor D1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of KLRD1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:164,730,833...164,742,539
Ensembl chr 4:163,045,067...163,056,518
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G |
Klrg1 |
killer cell lectin like receptor G1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of KLRG1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:157,127,571...157,139,372
Ensembl chr 4:155,455,495...155,467,424
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G |
Kng2 |
kininogen 2 |
decreases expression |
EXP |
Fructose results in decreased expression of MAP1 protein |
CTD |
PMID:26930160 |
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NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
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G |
Knl1 |
kinetochore scaffold 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of KNL1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:106,029,661...106,091,915
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G |
Krt17 |
keratin 17 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of KRT17 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of KRT17 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,178,675...85,183,392
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G |
Krt18 |
keratin 18 |
increases expression |
EXP |
Fructose increases expression of Krt18 protein in liver and serum |
RGD |
PMID:29989845 |
RGD:26884460 |
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:133,157,475...133,161,166 Ensembl chr10:133,157,475...133,161,166
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G |
Krt20 |
keratin 20 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of KRT20 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of KRT20 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107
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G |
Krt5 |
keratin 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of KRT5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:134,724,840...134,730,569
Ensembl chr 7:132,846,136...132,851,850
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G |
Kynu |
kynureninase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of KYNU mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:27,778,772...27,929,488
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G |
Lax1 |
lymphocyte transmembrane adaptor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of LAX1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381
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G |
Lca5l |
lebercilin LCA5 like |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LCA5L mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:35,460,646...35,495,133
Ensembl chr11:35,461,118...35,495,047
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G |
Lcn2 |
lipocalin 2 |
multiple interactions |
EXP ISO |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; [Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of LCN2 protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein] [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LCN2 mRNA |
CTD |
PMID:30551545 PMID:32259528 PMID:37567420 |
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NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095
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G |
Lct |
lactase |
increases expression |
EXP |
Fructose results in increased expression of LCT mRNA |
CTD |
PMID:11242478 |
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NCBI chr13:42,334,347...42,376,872
Ensembl chr13:39,781,929...39,824,456
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G |
Ldhb |
lactate dehydrogenase B |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of LDHB protein |
CTD |
PMID:26930160 |
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NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:175,428,385...175,446,403
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G |
Lep |
leptin |
increases secretion multiple interactions increases expression |
EXP ISO |
Fructose results in increased secretion of LEP protein [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LEP mRNA Fructose results in increased expression of LEP mRNA; Fructose results in increased expression of LEP protein [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of LEP mRNA]; [Ozone co-treated with Fructose] results in increased expression of LEP mRNA; [Particulate Matter co-treated with Fructose] results in increased expression of LEP mRNA; [Particulate Matter co-treated with Ozone co-treated with Fructose] results in increased expression of LEP mRNA; Allopurinol inhibits the reaction [Fructose results in increased expression of LEP protein]; Atorvastatin affects the reaction [Fructose results in increased expression of LEP protein]; Fenofibrate inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Quercetin inhibits the reaction [Fructose results in increased expression of LEP protein]; Quercetin inhibits the reaction [Fructose results in increased secretion of LEP protein]; Resveratrol inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Rutin inhibits the reaction [Fructose results in increased expression of LEP protein] |
CTD |
PMID:10780946 PMID:11741341 PMID:18627777 PMID:19165636 PMID:21122807 PMID:22426011 PMID:23016136 PMID:23533474 PMID:23968387 PMID:26973390 PMID:33118400 PMID:37567420 More...
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NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262
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G |
Lepr |
leptin receptor |
multiple interactions |
EXP |
Allopurinol inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein]; Fructose results in increased expression of and results in increased phosphorylation of LEPR protein; Quercetin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein]; Rutin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] |
CTD |
PMID:22426011 |
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NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
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G |
Lgals1 |
galectin 1 |
increases expression |
EXP |
Fructose results in increased expression of LGALS1 mRNA |
CTD |
PMID:37121297 |
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NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:110,481,392...110,488,345
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G |
Lgals3bp |
galectin 3 binding protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of LGALS3BP mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
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G |
Lgals9 |
galectin 9 |
multiple interactions decreases expression |
EXP |
Allopurinol inhibits the reaction [Fructose results in decreased expression of LGALS9 mRNA]; Allopurinol inhibits the reaction [Fructose results in decreased expression of LGALS9 protein]; Quercetin inhibits the reaction [Fructose results in decreased expression of LGALS9 mRNA]; Quercetin inhibits the reaction [Fructose results in decreased expression of LGALS9 protein]; Rutin inhibits the reaction [Fructose results in decreased expression of LGALS9 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of LGALS9 protein] Fructose results in decreased expression of LGALS9 mRNA; Fructose results in decreased expression of LGALS9 protein |
CTD |
PMID:19605544 |
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NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein] |
CTD |
PMID:34656705 |
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NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lin7b |
lin-7 homolog B, crumbs cell polarity complex component |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LIN7B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:104,983,368...104,986,795
Ensembl chr 1:95,846,243...95,849,977
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G |
Lipe |
lipase E, hormone sensitive type |
multiple interactions decreases expression |
EXP |
bisphenol A promotes the reaction [Fructose results in decreased expression of LIPE mRNA]; bisphenol A promotes the reaction [Fructose results in decreased expression of LIPE protein]; Fructose promotes the reaction [bisphenol A results in decreased expression of LIPE mRNA]; Fructose promotes the reaction [bisphenol A results in decreased expression of LIPE protein] Fructose results in decreased expression of LIPE mRNA; Fructose results in decreased expression of LIPE protein |
CTD |
PMID:31661889 |
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NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:80,965,627...80,984,310
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G |
Llcfc1 |
LLLL and CFNLAS motif containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LLCFC1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LLCFC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:70,566,206...70,567,592
Ensembl chr 4:70,566,295...70,567,586
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G |
Lmod3 |
leiomodin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of LMOD3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:131,400,643...131,415,411
Ensembl chr 4:129,843,970...129,858,244
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of LPL mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249
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G |
Lrch4 |
leucine rich repeats and calponin homology domain containing 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LRCH4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:24,694,364...24,709,354
Ensembl chr12:19,057,587...19,068,577
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G |
Lrrc26 |
leucine rich repeat containing 26 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LRRC26 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:28,500,517...28,501,843
Ensembl chr 3:8,102,361...8,103,687
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G |
Lrrc3b |
leucine rich repeat containing 3B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LRRC3B mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:9,973,580...10,050,891
Ensembl chr15:9,969,983...10,051,066
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G |
Lrrn2 |
leucine rich repeat neuronal 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of LRRN2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:46,874,048...46,934,544
Ensembl chr13:44,321,364...44,382,482
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G |
Lrrtm1 |
leucine rich repeat transmembrane neuronal 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of LRRTM1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:109,701,815...109,718,924
Ensembl chr 4:109,701,815...109,717,184
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G |
Lst1 |
leukocyte specific transcript 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of LST1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:3,639,353...3,644,399
Ensembl chr20:3,634,749...3,637,997
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G |
Mall |
mal, T-cell differentiation protein-like |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MALL mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:114,927,897...114,950,840
Ensembl chr 3:114,927,897...114,950,785
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G |
Maoa |
monoamine oxidase A |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of MAOA protein |
CTD |
PMID:26930160 |
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NCBI chr X:8,615,239...8,681,372
Ensembl chr X:6,030,795...6,099,593
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G |
Maob |
monoamine oxidase B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of MAOB mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MAOB mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:8,490,405...8,594,065
Ensembl chr X:5,907,266...6,011,003
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased lipidation of MAP1LC3B protein]; [Dietary Fats co-treated with Fructose] results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:34939712 |
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NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation decreases phosphorylation multiple interactions |
EXP |
Fructose results in increased phosphorylation of MAPK1 protein Fructose results in decreased phosphorylation of MAPK1 protein Curcumin inhibits the reaction [Fructose results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK1 protein] |
CTD |
PMID:22426011 PMID:26713546 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation decreases phosphorylation multiple interactions |
EXP |
Fructose results in increased phosphorylation of MAPK3 protein Fructose results in decreased phosphorylation of MAPK3 protein Curcumin inhibits the reaction [Fructose results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK3 protein] |
CTD |
PMID:22426011 PMID:26713546 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
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|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases expression |
EXP |
imoxin inhibits the reaction [Fructose results in increased expression of MAPK8 protein] |
CTD |
PMID:29430716 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
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|
G |
Mapt |
microtubule-associated protein tau |
decreases expression |
EXP |
Fructose results in decreased expression of MAPT protein |
CTD |
PMID:37121297 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129
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|
G |
Mcub |
mitochondrial calcium uniporter dominant negative subunit beta |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MCUB mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:221,153,525...221,223,814
Ensembl chr 2:218,479,301...218,549,593
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|
G |
Mef2c |
myocyte enhancer factor 2C |
increases expression |
EXP |
Fructose results in increased expression of MEF2C mRNA |
CTD |
PMID:36049592 |
|
NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880
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|
G |
Meig1 |
meiosis/spermiogenesis associated 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MEIG1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr17:74,810,791...74,828,433
Ensembl chr17:74,814,632...74,828,433
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|
G |
Meiob |
meiosis specific with OB-fold |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MEIOB mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:14,336,869...14,369,566
Ensembl chr10:13,833,750...13,865,046
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|
G |
Mesp2 |
mesoderm posterior bHLH transcription factor 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MESP2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:143,165,914...143,168,520
Ensembl chr 1:133,756,601...133,759,198
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|
G |
Mfap4 |
microfibril associated protein 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MFAP4 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,167,217...46,170,155
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|
G |
Mfap5 |
microfibril associated protein 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MFAP5 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:157,399,919...157,422,448
Ensembl chr 4:155,727,925...155,750,458
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|
G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
Fructose inhibits the reaction [Tribulus extract results in decreased expression of MFN1 protein] |
CTD |
PMID:36214339 |
|
NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:115,313,401...115,359,640
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO |
[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] |
CTD |
PMID:32730863 |
|
NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342
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|
G |
Mfsd2a |
MFSD2 lysolipid transporter A, lysophospholipid |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MFSD2A mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:135,225,816...135,240,690
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|
G |
Miat |
myocardial infarction associated transcript |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MIAT mRNA |
CTD |
PMID:37567420 |
|
NCBI chr12:44,414,620...44,429,852
|
|
G |
Mir33 |
microRNA 33 |
multiple interactions |
EXP |
[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA] |
CTD |
PMID:31468622 |
|
NCBI chr 7:115,593,952...115,594,020
Ensembl chr 7:113,713,855...113,713,923
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|
G |
Mir99a |
microRNA 99a |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MIR99A mRNA |
CTD |
PMID:37567420 |
|
NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
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|
G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MKI67 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762
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|
G |
Mlx |
MAX dimerization protein MLX |
increases expression |
EXP |
Fructose results in increased expression of MLX mRNA |
CTD |
PMID:18346472 |
|
NCBI chr10:86,519,517...86,524,607
Ensembl chr10:86,019,588...86,032,350
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|
G |
Mlxipl |
MLX interacting protein-like |
multiple interactions decreases expression increases expression increases activity |
EXP ISO |
Atorvastatin inhibits the reaction [Fructose affects the localization of and results in increased activity of MLXIPL protein]; Atorvastatin inhibits the reaction [Fructose results in increased expression of MLXIPL protein]; Fructose affects the localization of and results in increased activity of MLXIPL protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin inhibits the reaction [Fructose results in increased activity of MLXIPL protein]] Fructose results in decreased expression of MLXIPL mRNA Fructose results in increased expression of MLXIPL mRNA alternative form FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of MLXIPL mRNA alternative form]; MLXIPL gene mutant form inhibits the reaction [Fructose results in increased expression of FGF21 mRNA]; MLXIPL gene mutant form inhibits the reaction [Fructose results in increased secretion of FGF21 protein] Fructose results in increased expression of MLXIPL mRNA; Fructose results in increased expression of MLXIPL protein |
CTD |
PMID:18346472 PMID:19053045 PMID:19799862 PMID:21122807 PMID:28123933 |
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NCBI chr12:27,178,158...27,213,675
Ensembl chr12:21,543,576...21,577,112
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G |
Mlycd |
malonyl-CoA decarboxylase |
multiple interactions decreases expression |
EXP |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; resveratrol inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA] |
CTD |
PMID:26973390 |
|
NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
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G |
Mmp12 |
matrix metallopeptidase 12 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MMP12 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611
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|
G |
Mmp19 |
matrix metallopeptidase 19 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MMP19 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:1,805,732...1,814,054
Ensembl chr 7:1,221,343...1,229,555
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|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
[FGF21 gene mutant form results in increased susceptibility to Fructose] which results in increased expression of MMP2 mRNA |
CTD |
PMID:28123933 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp25 |
matrix metallopeptidase 25 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MMP25 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:12,661,297...12,676,119
Ensembl chr10:12,661,208...12,675,871
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|
G |
Mmp7 |
matrix metallopeptidase 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MMP7 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression |
ISO |
Fructose results in increased expression of MMP9 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
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G |
Mnda |
myeloid cell nuclear differentiation antigen |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of IFI204 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr13:88,550,224...88,567,892
Ensembl chr13:86,017,892...86,034,201
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G |
Mogat2 |
monoacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MOGAT2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
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G |
Mpst |
mercaptopyruvate sulfurtransferase |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of MPST protein |
CTD |
PMID:26930160 |
|
NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141
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G |
Mpv17l |
MPV17 mitochondrial inner membrane protein like |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MPV17L mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:2,495,605...2,532,448
Ensembl chr10:1,988,136...2,007,649
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G |
Mrap |
melanocortin 2 receptor accessory protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MRAP mRNA |
CTD |
PMID:37567420 |
|
NCBI chr11:43,477,382...43,489,118
Ensembl chr11:29,992,034...30,003,024
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G |
Mro |
maestro |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of MRO mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MRO mRNA |
CTD |
PMID:37567420 |
|
NCBI chr18:69,723,764...69,742,815
Ensembl chr18:67,450,595...67,467,044
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G |
Ms4a1 |
membrane spanning 4-domains A1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of MS4A1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MS4A1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:207,906,374...207,918,512
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G |
Ms4a6a |
membrane spanning 4-domains A6A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MS4A6C mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:208,401,466...208,414,758
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|
G |
Msh4 |
mutS homolog 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MSH4 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 2:245,445,118...245,504,493
Ensembl chr 2:242,792,661...242,843,487
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G |
Msn |
moesin |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of MSN protein |
CTD |
PMID:26930160 |
|
NCBI chr X:65,005,546...65,073,512
Ensembl chr X:60,995,951...61,065,628
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|
G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MSR1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr16:59,421,250...59,507,070
Ensembl chr16:52,717,732...52,799,676
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
increases expression |
EXP |
Fructose results in increased expression of ATP6 protein |
CTD |
PMID:11934685 |
|
Ensembl chr MT:7,919...8,599
|
|
G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of COX2 protein |
CTD |
PMID:26930160 |
|
NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
|
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G |
Mt1-ps2 |
metallothionein 1, pseudogene 2 |
multiple interactions increases expression |
EXP |
Atorvastatin inhibits the reaction [Fructose results in increased expression of MT1-PS2 mRNA] |
CTD |
PMID:21122807 |
|
|
|
G |
Mt2 |
metallothionein 2 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of MT2A mRNA Atorvastatin inhibits the reaction [Fructose results in increased expression of MT2A mRNA] |
CTD |
PMID:21122807 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
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G |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of MTHFD2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:115,811,139...115,822,608
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
EXP |
[dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of and results in increased phosphorylation of MTOR protein]; [Dietary Fats co-treated with Fructose] results in increased expression of and results in increased phosphorylation of MTOR protein |
CTD |
PMID:34939712 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
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|
G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions increases expression |
EXP ISO |
[Fructose co-treated with Copper deficiency] results in decreased expression of MTTP mRNA FGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of MTTP mRNA] |
CTD |
PMID:25813056 PMID:28123933 |
|
NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:226,613,090...226,654,239
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G |
Muc16 |
mucin 16, cell surface associated |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MUC16 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:24,440,840...24,644,494
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G |
Muc19 |
mucin 19, oligomeric |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of MUC19 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 7:124,897,424...125,018,582
Ensembl chr 7:123,017,896...123,139,053
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|
G |
Mx1 |
MX dynamin like GTPase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of MX1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr11:50,269,056...50,294,699
Ensembl chr11:36,799,660...36,823,507
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|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
Fructose results in decreased expression of MYC mRNA |
CTD |
PMID:2558650 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
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|
G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
Fructose promotes the reaction [Ethanol results in increased expression of MYD88 mRNA] |
CTD |
PMID:26858005 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
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|
G |
Myh1 |
myosin heavy chain 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYH1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:52,384,810...52,408,698
Ensembl chr10:51,885,913...51,946,295
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|
G |
Myh15 |
myosin, heavy chain 15 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of MYH15 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr11:65,084,666...65,226,010
Ensembl chr11:51,622,413...51,762,971
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G |
Myh6 |
myosin heavy chain 6 |
increases expression multiple interactions |
ISO |
Fructose results in increased expression of MYH6 mRNA SIRT1 protein affects the reaction [Fructose results in increased expression of MYH6 mRNA] |
CTD |
PMID:18192211 |
|
NCBI chr15:32,388,102...32,413,663
Ensembl chr15:28,417,616...28,441,720
|
|
G |
Myh9 |
myosin, heavy chain 9 |
decreases expression multiple interactions |
EXP |
Fructose results in decreased expression of MYH9 protein [Fructose co-treated with bisphenol A] results in increased expression of MYH9 protein |
CTD |
PMID:26930160 |
|
NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457
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G |
Myo5a |
myosin VA |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYO5A mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:75,812,412...75,975,918
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G |
Myom3 |
myomesin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYOM3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274
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|
G |
Nalcn |
sodium leak channel, non-selective |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NALCN mRNA |
CTD |
PMID:37567420 |
|
NCBI chr15:100,398,583...100,741,243
Ensembl chr15:100,398,615...100,741,001
|
|
G |
Nanp |
N-acetylneuraminic acid phosphatase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NANP mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648
|
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G |
Ncapg |
non-SMC condensin I complex, subunit G |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCAPG mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:69,616,473...69,645,445
Ensembl chr14:65,404,163...65,432,902
|
|
G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCF1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:28,121,816...28,131,080
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf4 |
neutrophil cytosolic factor 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of NCF4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:111,705,926...111,723,893
Ensembl chr 7:109,826,020...109,843,389
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G |
Ncr1 |
natural cytotoxicity triggering receptor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCR1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:78,657,409...78,665,255
Ensembl chr 1:69,616,601...69,660,558
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G |
Ndufa5 |
NADH:ubiquinone oxidoreductase subunit A5 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in increased expression of NDUFA5 protein |
CTD |
PMID:26930160 |
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NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:52,995,546...53,005,598 Ensembl chr 5:52,995,546...53,005,598
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G |
Ndufa9 |
NADH:ubiquinone oxidoreductase subunit A9 |
multiple interactions |
EXP |
[Fructose co-treated with bisphenol A] results in decreased expression of NDUFA9 protein |
CTD |
PMID:26930160 |
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NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:159,659,242...159,688,018
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G |
Nek2 |
NIMA-related kinase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NEK2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
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G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of NFATC4 protein tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of NFATC4 protein] |
CTD |
PMID:26358169 |
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NCBI chr15:33,256,912...33,284,522
Ensembl chr15:29,305,535...29,314,610
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G |
Nfe2 |
nuclear factor, erythroid 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NFE2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:136,261,234...136,273,850
Ensembl chr 7:134,382,761...134,390,108
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
ISO EXP |
Fructose results in increased expression of NFE2L2 protein [Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein] [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]; [Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein] Fructose promotes the reaction [PPARD gene mutant form results in increased phosphorylation of NFE2L2 protein]; Plant Preparations inhibits the reaction [Fructose results in increased expression of NFE2L2 protein] |
CTD |
PMID:27531227 PMID:29289645 PMID:32259528 PMID:32730863 |
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NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
increases degradation decreases expression increases phosphorylation multiple interactions |
EXP |
Fructose results in increased degradation of NFKBIA protein Fructose results in decreased expression of NFKBIA protein Fructose results in increased phosphorylation of NFKBIA protein Allopurinol inhibits the reaction [Fructose results in increased phosphorylation of NFKBIA protein]; bisphenol A promotes the reaction [Fructose results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Fructose results in increased degradation of NFKBIA protein]; Fructose promotes the reaction [bisphenol A results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Fructose results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:24491314 PMID:26713546 PMID:31661889 |
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NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbid |
NFKB inhibitor delta |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NFKBID mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:85,680,861...85,690,447
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G |
Ngf |
nerve growth factor |
decreases expression |
EXP |
Fructose results in decreased expression of NGF mRNA; Fructose results in decreased expression of NGF protein |
CTD |
PMID:18585860 |
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NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452
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G |
Ngfr |
nerve growth factor receptor |
decreases expression |
EXP |
Fructose results in decreased expression of NGFR mRNA |
CTD |
PMID:18585860 |
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NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518
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G |
Nkg7 |
natural killer cell granule protein 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NKG7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:93,844,902...93,845,983
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G |
Nkpd1 |
NTPase, KAP family P-loop domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of NKPD1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:79,165,642...79,175,126
Ensembl chr 1:79,167,130...79,174,234
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G |
Nlrc5 |
NLR family, CARD domain containing 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NLRC5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,477,628...10,562,121
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression multiple interactions |
EXP |
Fructose results in increased expression of NLRP3 protein [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein; Allopurinol inhibits the reaction [Fructose results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of NLRP3 protein]; Rutin inhibits the reaction [Fructose results in increased expression of NLRP3 protein] |
CTD |
PMID:22426011 PMID:24491314 PMID:34939712 |
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NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
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G |
Nobox |
NOBOX oogenesis homeobox |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NOBOX mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:73,128,926...73,134,431
Ensembl chr 4:72,128,931...72,134,436
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G |
Nog |
noggin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of NOG mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression |
EXP ISO |
[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein; [Fructose results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide; bisphenol A diglycidyl ether inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]]; caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]; iodopravadoline inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]]; Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]; Resveratrol inhibits the reaction [Fructose results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [Fructose results in increased expression of NOS2 protein] Fructose results in increased expression of INOS mRNA; Fructose results in increased expression of INOS protein; Fructose results in increased expression of NOS2 mRNA; Fructose results in increased expression of NOS2 protein |
CTD |
PMID:10090849 PMID:26488877 PMID:28257781 PMID:30343038 PMID:30480462 |
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NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions decreases expression decreases phosphorylation decreases activity |
EXP ISO |
[bisphenol A co-treated with Fructose] results in increased expression of NOS3 mRNA; [Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein; [Resveratrol co-treated with Fructose] results in increased expression of NOS3 mRNA; bisphenol A diglycidyl ether inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein]]; caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein]; Fish Oils inhibits the reaction [Fructose results in decreased expression of NOS3 mRNA]; Fish Oils inhibits the reaction [Fructose results in decreased expression of NOS3 protein]; iodopravadoline inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein]]; Metformin inhibits the reaction [Fructose results in decreased phosphorylation of NOS3 protein]; NOS3 protein inhibits the reaction [Fructose results in decreased expression of IRS1 protein]; NOS3 protein inhibits the reaction [Fructose results in decreased expression of IRS2 protein]; NOS3 protein inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]; Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Fructose results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Fructose results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Fructose results in decreased phosphorylation of NOS3 protein] Fructose results in decreased expression of NOS3 mRNA; Fructose results in decreased expression of NOS3 protein Fructose results in decreased activity of NOS3 protein |
CTD |
PMID:10580434 PMID:15752949 PMID:18508964 PMID:19008412 PMID:25108154 PMID:26488877 PMID:27622962 PMID:30343038 More...
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NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166
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G |
Nox4 |
NADPH oxidase 4 |
increases expression |
EXP |
Fructose results in increased expression of NOX4 mRNA |
CTD |
PMID:17587757 |
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NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406
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G |
Nppb |
natriuretic peptide B |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein] |
CTD |
PMID:34801538 |
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NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:158,416,866...158,418,168
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G |
Npy |
neuropeptide Y |
decreases expression multiple interactions |
EXP ISO |
Fructose results in decreased expression of NPY mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NPY mRNA |
CTD |
PMID:18627777 PMID:37567420 |
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NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions |
ISO |
NR0B2 protein inhibits the reaction [AHR protein results in increased susceptibility to [Dietary Fats co-treated with Fructose]]; NR0B2 protein results in decreased susceptibility to [Dietary Fats co-treated with Fructose] |
CTD |
PMID:29416063 |
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NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr2f1 |
nuclear receptor subfamily 2, group F, member 1 |
multiple interactions |
ISO |
Fructose affects the reaction [NR2F1 protein binds to SHBG promoter] |
CTD |
PMID:17992261 |
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NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:8,040,377...8,050,123
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NRG1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884
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G |
Nt5c1a |
5'-nucleotidase, cytosolic IA |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NT5C1A mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:135,473,107...135,494,400
Ensembl chr 5:135,473,231...135,499,338
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G |
Nt5dc2 |
5'-nucleotidase domain containing 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NT5DC2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537
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G |
Ntm |
neurotrimin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NTM mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NTM mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:35,634,929...36,625,081
Ensembl chr 8:27,377,773...28,366,595
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G |
Nudt8 |
nudix hydrolase 8 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NUDT8 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:210,723,209...210,724,717
Ensembl chr 1:201,292,619...201,295,224
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NUF2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:84,226,448...84,290,957
Ensembl chr13:81,693,598...81,722,766
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G |
Nxnl1 |
nucleoredoxin-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of NXNL1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:18,270,604...18,279,797
Ensembl chr16:18,262,688...18,279,987
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G |
Nxpe3 |
neurexophilin and PC-esterase domain family, member 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NXPE3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:58,195,951...58,246,739
Ensembl chr11:44,727,069...44,777,694
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G |
Nxph4 |
neurexophilin 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of NXPH4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:63,367,758...63,376,579
Ensembl chr 7:63,367,761...63,376,579
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G |
Oas1a |
2'-5' oligoadenylate synthetase 1A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of OAS1G mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517
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G |
Oas2 |
2'-5' oligoadenylate synthetase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of OAS2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:41,464,568...41,492,036
Ensembl chr12:35,806,759...35,829,371
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G |
Oasl |
2'-5'-oligoadenylate synthetase-like |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of OASL1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Fructose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein]; Fructose inhibits the reaction [Cyclic AMP results in increased expression of OAT mRNA] |
CTD |
PMID:2827574 |
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NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:187,347,865...187,367,682
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G |
Obscn |
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of OBSCN mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of OBSCN mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:44,273,686...44,419,275
Ensembl chr10:43,789,293...43,919,723
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G |
Oga |
O-GlcNAcase |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein] |
CTD |
PMID:30551545 |
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NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:244,598,292...244,634,359
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G |
Olfml1 |
olfactomedin-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of OLFML1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] |
CTD |
PMID:32730863 |
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NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109
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G |
Otop1 |
otopetrin 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of OTOP1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:76,717,330...76,744,785
Ensembl chr14:72,503,592...72,532,497
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G |
Ovol3 |
ovo-like zinc finger 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of OVOL3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:94,612,417...94,616,053
Ensembl chr 1:85,484,956...85,488,592
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G |
P2rx2 |
purinergic receptor P2X 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of P2RX2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:51,999,107...52,002,627
Ensembl chr12:46,339,549...46,342,891
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G |
P2ry10 |
P2Y receptor family member 10 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of P2RY10 mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:76,184,064...76,279,996
Ensembl chr X:72,111,264...72,212,265
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G |
Pabpc1l |
poly(A) binding protein, cytoplasmic 1-like |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of PABPC1L mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:173,111,856...173,145,389
Ensembl chr 3:152,693,700...152,725,997
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G |
Paip2 |
poly(A) binding protein interacting protein 2 |
multiple interactions |
ISO |
Fructose promotes the reaction [PAIP2 protein binds to SLC2A5 3' UTR] |
CTD |
PMID:12820898 |
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NCBI chr18:27,475,278...27,492,452
Ensembl chr18:27,199,796...27,214,863 Ensembl chr 1:27,199,796...27,214,863
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G |
Pappa2 |
pappalysin 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of PAPPA2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:73,407,385...73,683,699
Ensembl chr13:70,876,794...71,147,779
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases expression |
ISO |
Fructose results in increased expression of PARP1 protein |
CTD |
PMID:28257781 |
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NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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G |
Parp14 |
poly (ADP-ribose) polymerase family, member 14 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PARP14 mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:78,408,134...78,440,201
Ensembl chr11:64,902,785...64,934,916
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G |
Pax5 |
paired box 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of PAX5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:63,554,784...63,741,380
Ensembl chr 5:58,765,036...58,944,326
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G |
Pax6 |
paired box 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of PAX6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014
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G |
Pbk |
PDZ binding kinase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of PBK mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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G |
Pbx4 |
PBX homeobox 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of PBX4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:19,588,998...19,624,016
Ensembl chr16:19,555,090...19,590,014
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G |
Pcdh10 |
protocadherin 10 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of PCDH10 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:130,553,432...130,619,591
Ensembl chr 2:128,617,174...128,677,190
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G |
Pcdhga8 |
protocadherin gamma subfamily A, 8 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of PCDHGA8 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:29,553,882...29,667,865
Ensembl chr18:29,493,954...29,667,868
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression increases activity |
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