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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:palmitoleic acid
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Accession:CHEBI:28716 term browser browse the term
Definition:A hexadec-9-enoic acid in which the double bond at position C-9 has cis configuration.
Synonyms:related_synonym: (9Z)-Hexadecenoic acid;   (9Z)-hexadec-9-enoic acid;   (Z)-9-hexadecenoic acid;   (Z)-hexadec-9-enoic acid;   16:1Delta9;   9-cis-hexadecenoic acid;   Oleopalmitic acid;   Zoomeric acid;   cis-9-Palmitoleic acid;   cis-Palmitoleic acid;   cis-delta-9-Hexadecenoic acid;   palmitolinoleic acid;   zoomaric acid
 alt_id: CHEBI:25836;   CHEBI:44696;   CHEBI:7897
 xref: CAS:373-49-9;   DrugBank:DB04257;   HMDB:HMDB0003229;   KNApSAcK:C00001234;   KNApSAcK:C00029354
 xref_mesh: MESH:C008757
 xref: Reaxys:1725389;   kegg.compound:C08362;   lipidmaps:LMFA01030056;   pdb-ccd:PAM;   pubmed:19761868;   pubmed:24362891
 chemrof_formula: C16H30O2
 chemrof_smiles: CCCCCC/C=CCCCCCCCC(=O)O
 chemrof_inchi: InChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7-
 chemrof_inchikey: SECPZKHBENQXJG-FPLPWBNLSA-N
 cyclic_relationship: is_conjugate_acid_of CHEBI:32372


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palmitoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases degradation
increases phosphorylation
multiple interactions 		ISO palmitoleic acid results in increased degradation of ABCA1 protein
palmitoleic acid results in increased phosphorylation of ABCA1 protein
palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] 		CTD PMID:16118212 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] CTD PMID:16118212 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid] CTD PMID:39172838 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Il6 interleukin 6 increases expression ISO palmitoleic acid results in increased expression of IL6 mRNA CTD PMID:30524225 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of palmitoleic acid analog CTD PMID:26820058 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [Glucose deficiency co-treated with palmitoleic acid] results in increased expression of PCK1 mRNA CTD PMID:8536680 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity 		ISO palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; palmitoleic acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]
palmitoleic acid results in decreased activity of PON1 protein 		CTD PMID:12871208 PMID:15375178 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid] CTD PMID:39172838 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        biochemical role 19888
          metabolite 19624
            eukaryotic metabolite 19368
              algal metabolite 7660
                palmitoleic acid 8
                  2-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphocholine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            heteroorganic entity 20201
                              organochalcogen compound 19822
                                organooxygen compound 19713
                                  carbon oxoacid 17678
                                    carboxylic acid 17675
                                      monocarboxylic acid 17142
                                        fatty acid 14785
                                          unsaturated fatty acid 941
                                            monounsaturated fatty acid 480
                                              hexadecenoic acid 8
                                                hexadec-9-enoic acid 8
                                                  palmitoleic acid 8
                                                    2-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphocholine 0
paths to the root