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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chloroethene
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Accession:CHEBI:28509 term browser browse the term
Definition:A monohaloethene that is ethene in which one of the hydrogens has been replaced by a chloro group.
Synonyms:related_synonym: Chloroethylene;   VC;   Vinyl chloride;   Vinylchlorid;   chlorure de vinyle;   cloroetileno;   cloruro de vinilo;   ethylene monochloride;   monochloroethene;   monochloroethylene;   monovinyl chloride
 alt_id: CHEBI:27293;   CHEBI:9990
 xref: CAS:75-01-4;   Gmelin:100541
 xref_mesh: MESH:D014752
 xref: Reaxys:1731576;   kegg.compound:C06793;   pubmed:15989139;   pubmed:18678006;   umbbd.compound:c0358;   wikipedia.en:Chloroethene
 chemrof_inchikey: BZHJMEDXRYGGRV-UHFFFAOYSA-N
 chemrof_formula: C2H3Cl
 chemrof_smiles: C=CCl
 chemrof_inchi: InChI=1S/C2H3Cl/c1-2-3/h2H,1H2


show annotations for term's descendants           Sort by:
chloroethene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd3 ATP-binding cassette, sub-family D member 3 increases expression EXP Vinyl Chloride results in increased expression of ABCD3 mRNA CTD PMID:18579281 NCBI chr 3:121,552,553...121,609,851
Ensembl chr 3:121,552,423...121,608,951 		JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases expression EXP Vinyl Chloride results in increased expression of ACACA mRNA; Vinyl Chloride results in increased expression of ACACA protein CTD PMID:31445928 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477 		JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression EXP Vinyl Chloride results in decreased expression of ACER2 mRNA CTD PMID:18579281 NCBI chr 4:86,792,585...86,853,059
Ensembl chr 4:86,792,633...86,853,059 		JBrowse link
G Acly ATP citrate lyase increases expression EXP Vinyl Chloride metabolite results in increased expression of ACLY mRNA; Vinyl Chloride results in increased expression of ACLY mRNA CTD PMID:18579281 PMID:26962056 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions EXP [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of ACOX1 mRNA CTD PMID:37061008 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression EXP Vinyl Chloride results in increased expression of ACSS2 mRNA CTD PMID:18579281 NCBI chr 2:155,359,963...155,404,663
Ensembl chr 2:155,359,868...155,427,644 		JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 increases expression EXP Vinyl Chloride results in increased expression of ADGRB2 mRNA CTD PMID:18579281 NCBI chr 4:129,878,566...129,916,426
Ensembl chr 4:129,878,663...129,916,426 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP Vinyl Chloride results in increased expression of ADH4 mRNA CTD PMID:18579281 NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653 		JBrowse link
G Agk acylglycerol kinase increases expression EXP Vinyl Chloride results in increased expression of AGK mRNA CTD PMID:18579281 NCBI chr 6:40,302,010...40,378,723
Ensembl chr 6:40,302,106...40,373,696 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions 		EXP Vinyl Chloride metabolite results in increased phosphorylation of AKT1 protein
Vinyl Chloride results in increased expression of and results in increased phosphorylation of AKT1 protein 		CTD PMID:26962056 PMID:36892438 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial increases response to substance ISO ALDH2 gene SNP results in increased susceptibility to Vinyl Chloride CTD PMID:20100738 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 increases activity ISO Vinyl Chloride results in increased activity of ALDH3A1 protein CTD PMID:15211785 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression EXP Vinyl Chloride results in decreased expression of ALPI mRNA CTD PMID:18579281 NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression EXP Vinyl Chloride results in decreased expression of ANGPTL4 mRNA CTD PMID:18579281 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804 		JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression EXP Vinyl Chloride results in increased expression of ARHGEF16 mRNA CTD PMID:18579281 NCBI chr 4:154,362,926...154,384,535
Ensembl chr 4:154,362,943...154,386,133 		JBrowse link
G Arsg arylsulfatase G increases expression EXP Vinyl Chloride results in increased expression of ARSG mRNA CTD PMID:18579281 NCBI chr11:109,364,159...109,464,156
Ensembl chr11:109,364,200...109,464,156 		JBrowse link
G Atl1 atlastin GTPase 1 increases expression EXP Vinyl Chloride results in increased expression of ATL1 mRNA CTD PMID:18579281 NCBI chr12:69,939,879...70,010,859
Ensembl chr12:69,939,388...70,013,191 		JBrowse link
G Bsg basigin decreases expression EXP Vinyl Chloride results in decreased expression of BSG mRNA CTD PMID:18579281 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Car11 carbonic anhydrase 11 decreases expression EXP Vinyl Chloride results in decreased expression of CAR11 mRNA CTD PMID:18579281 NCBI chr 7:45,348,537...45,354,106
Ensembl chr 7:45,349,267...45,354,106 		JBrowse link
G Casp1 caspase 1 increases expression EXP Vinyl Chloride results in increased expression of CASP1 protein modified form CTD PMID:34717031 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp14 caspase 14 increases expression EXP Vinyl Chloride results in increased expression of CASP14 mRNA CTD PMID:18579281 NCBI chr10:78,547,829...78,554,181
Ensembl chr10:78,547,825...78,554,128 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CCL2 protein; [Vinyl Chloride co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CCL2 mRNA CTD PMID:31774537 PMID:34717031 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CCL3 protein CTD PMID:31774537 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccn3 cellular communication network factor 3 multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] affects the expression of CCN3 protein CTD PMID:36892438 NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435 		JBrowse link
G Ccnb1 cyclin B1 increases expression EXP Vinyl Chloride results in increased expression of CCNB1 mRNA CTD PMID:18579281 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Cd40 CD40 antigen increases expression EXP Vinyl Chloride results in increased expression of CD40 protein CTD PMID:36892438 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd48 CD48 antigen increases expression EXP Vinyl Chloride results in increased expression of CD48 protein CTD PMID:36892438 NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826 		JBrowse link
G Cdh17 cadherin 17 increases expression EXP Vinyl Chloride results in increased expression of CDH17 mRNA CTD PMID:18579281 NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A affects response to substance ISO CDKN2A polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cenpe centromere protein E increases expression EXP Vinyl Chloride results in increased expression of CENPE mRNA CTD PMID:18579281 NCBI chr 3:134,918,324...134,979,301
Ensembl chr 3:134,918,298...134,979,372 		JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 increases expression EXP Vinyl Chloride results in increased expression of CHRNA4 mRNA CTD PMID:18579281 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339 		JBrowse link
G Cirbp cold inducible RNA binding protein increases expression EXP Vinyl Chloride results in increased expression of CIRBP mRNA CTD PMID:18579281 NCBI chr10:80,001,824...80,008,620
Ensembl chr10:80,001,819...80,008,620 		JBrowse link
G Col15a1 collagen, type XV, alpha 1 increases expression EXP Vinyl Chloride results in increased expression of COL15A1 mRNA CTD PMID:18579281 NCBI chr 4:47,207,744...47,313,165
Ensembl chr 4:47,208,161...47,313,167 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression
multiple interactions 		EXP Vinyl Chloride metabolite results in increased expression of CPT1A mRNA
[Dietary Fats co-treated with Vinyl Chloride] results in increased expression of CPT1A protein 		CTD PMID:26962056 PMID:36892438 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Cst3 cystatin C multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] affects the expression of CST3 protein CTD PMID:36892438 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CXCL10 protein CTD PMID:31774537 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of CXCL2 protein CTD PMID:31774537 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases response to substance
affects metabolic processing
increases metabolic processing
increases activity
affects response to substance
increases oxidation 		ISO CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]
CYP2E1 gene polymorphism results in increased susceptibility to Vinyl Chloride; CYP2E1 gene SNP results in increased susceptibility to Vinyl Chloride
CYP2E1 protein affects the metabolism of Vinyl Chloride
CYP2E1 protein results in increased metabolism of Vinyl Chloride
Vinyl Chloride results in increased activity of CYP2E1 protein
1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride]
CYP2E1 gene polymorphism affects the susceptibility to Vinyl Chloride
CYP2E1 protein results in increased oxidation of Vinyl Chloride 		CTD PMID:1664256 PMID:7871537 PMID:12010862 PMID:12705718 PMID:15211785 More... NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases expression EXP Vinyl Chloride results in decreased expression of CYP3A13 mRNA CTD PMID:18579281 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dcn decorin increases expression EXP Vinyl Chloride results in increased expression of DCN protein CTD PMID:36892438 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 decreases expression EXP Vinyl Chloride results in decreased expression of DKK3 mRNA CTD PMID:18579281 NCBI chr 7:111,715,226...111,758,689
Ensembl chr 7:111,715,224...111,758,264 		JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression EXP Vinyl Chloride results in increased expression of DUSP8 mRNA CTD PMID:18579281 NCBI chr 7:141,633,224...141,649,799
Ensembl chr 7:141,633,227...141,649,580 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression EXP Vinyl Chloride results in increased expression of EEPD1 mRNA CTD PMID:18579281 NCBI chr 9:25,392,809...25,515,406
Ensembl chr 9:25,392,843...25,515,406 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 increases response to substance ISO ERCC2 gene SNP results in increased susceptibility to Vinyl Chloride CTD PMID:18420361 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 affects response to substance ISO ERCC4 5' UTR SNP affects the susceptibility to Vinyl Chloride CTD PMID:21216194 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481 		JBrowse link
G Far1 fatty acyl CoA reductase 1 decreases expression EXP Vinyl Chloride results in decreased expression of FAR1 mRNA CTD PMID:18579281 NCBI chr 7:113,113,008...113,170,713
Ensembl chr 7:113,113,041...113,170,718 		JBrowse link
G Fasn fatty acid synthase increases expression EXP Vinyl Chloride results in increased expression of FASN mRNA; Vinyl Chloride results in increased expression of FASN protein CTD PMID:31445928 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fbxo41 F-box protein 41 increases expression EXP Vinyl Chloride results in increased expression of FBXO41 mRNA CTD PMID:18579281 NCBI chr 6:85,446,556...85,479,976
Ensembl chr 6:85,446,556...85,479,976 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb decreases expression EXP Vinyl Chloride results in decreased expression of FCGR2B protein CTD PMID:36892438 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Fdps farnesyl diphosphate synthetase increases expression EXP Vinyl Chloride results in increased expression of FDPS mRNA CTD PMID:18579281 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Fkbp5 FK506 binding protein 5 decreases expression EXP Vinyl Chloride results in decreased expression of FKBP5 mRNA CTD PMID:18579281 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501 		JBrowse link
G Folr1 folate receptor alpha increases expression EXP Vinyl Chloride results in increased expression of FOLR1 mRNA CTD PMID:18579281 NCBI chr 7:101,507,551...101,519,974
Ensembl chr 7:101,507,538...101,519,995 		JBrowse link
G G0s2 G0/G1 switch gene 2 decreases expression EXP Vinyl Chloride results in decreased expression of G0S2 mRNA CTD PMID:18579281 NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha affects response to substance ISO GADD45A polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gbp9 guanylate-binding protein 9 increases expression EXP Vinyl Chloride results in increased expression of GBP9 mRNA CTD PMID:18579281 NCBI chr 5:105,224,331...105,258,255
Ensembl chr 5:105,225,496...105,287,405 		JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression EXP Vinyl Chloride results in decreased expression of GDE1 mRNA CTD PMID:18579281 NCBI chr 7:118,287,781...118,304,961
Ensembl chr 7:118,287,768...118,305,001 		JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B increases expression EXP Vinyl Chloride results in increased expression of GMPPB mRNA CTD PMID:18579281 NCBI chr 9:107,926,490...107,929,119
Ensembl chr 9:107,926,441...107,930,000 		JBrowse link
G Gnb5 guanine nucleotide binding protein (G protein), beta 5 increases expression EXP Vinyl Chloride results in increased expression of GNB5 mRNA CTD PMID:18579281 NCBI chr 9:75,213,570...75,253,205
Ensembl chr 9:75,213,570...75,253,158 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble decreases expression
multiple interactions 		EXP Vinyl Chloride results in decreased expression of GOT1 mRNA
[Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased activity of GOT1 protein 		CTD PMID:18579281 PMID:37061008 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Gpa33 glycoprotein A33 transmembrane increases expression EXP Vinyl Chloride results in increased expression of GPA33 mRNA CTD PMID:18579281 NCBI chr 1:165,957,790...165,994,079
Ensembl chr 1:165,957,807...165,994,079 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Vinyl Chloride results in increased expression of GPAM mRNA CTD PMID:18579281 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670 		JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression EXP Vinyl Chloride results in decreased expression of GPR85 mRNA CTD PMID:18579281 NCBI chr 6:13,834,405...13,839,951
Ensembl chr 6:13,834,457...13,839,941 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble increases expression
multiple interactions 		EXP Vinyl Chloride results in increased expression of GPT protein
[Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased activity of GPT protein 		CTD PMID:31445928 PMID:37061008 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gramd1c GRAM domain containing 1C increases expression EXP Vinyl Chloride results in increased expression of GRAMD1C mRNA CTD PMID:18579281 NCBI chr16:43,800,713...43,883,757
Ensembl chr16:43,800,713...43,883,708 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression
multiple interactions 		EXP Vinyl Chloride metabolite results in increased expression of GSK3B mRNA
Vinyl Chloride results in increased expression of and results in increased phosphorylation of GSK3B protein 		CTD PMID:26962056 PMID:36892438 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions
increases expression 		ISO
EXP 		[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chloride; GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]
Vinyl Chloride results in increased expression of GSTM1 protein 		CTD PMID:16097394 PMID:16977343 PMID:36892438 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 affects response to substance
increases response to substance 		ISO GSTP1 gene polymorphism affects the susceptibility to Vinyl Chloride
GSTP1 gene SNP results in increased susceptibility to Vinyl Chloride 		CTD PMID:20100738 PMID:20134343 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 multiple interactions
increases response to substance 		ISO [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chloride; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]
GSTT1 gene polymorphism results in increased susceptibility to Vinyl Chloride 		CTD PMID:16097394 PMID:16270392 PMID:16977343 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP Vinyl Chloride results in decreased expression of HMOX1 mRNA; Vinyl Chloride results in decreased expression of HMOX1 protein CTD PMID:18579281 PMID:34717031 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hoxc8 homeobox C8 increases expression EXP Vinyl Chloride results in increased expression of HOXC8 mRNA CTD PMID:18579281 NCBI chr15:102,898,971...102,902,707
Ensembl chr15:102,899,039...102,902,543 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 increases expression EXP Vinyl Chloride results in increased expression of HSD3B5 mRNA CTD PMID:18579281 NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568 		JBrowse link
G Hspa5 heat shock protein 5 increases expression EXP Vinyl Chloride results in increased expression of HSPA5 mRNA CTD PMID:31445928 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspb8 heat shock protein 8 decreases expression EXP Vinyl Chloride results in decreased expression of HSPB8 mRNA CTD PMID:18579281 NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923 		JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 decreases expression EXP Vinyl Chloride results in decreased expression of HSPH1 mRNA CTD PMID:18579281 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression 		EXP [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of IFNG protein
Vinyl Chloride results in decreased expression of IFNG mRNA 		CTD PMID:31774537 PMID:34717031 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP Vinyl Chloride results in increased expression of IGF1 protein CTD PMID:36892438 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression
multiple interactions 		EXP Vinyl Chloride results in decreased expression of IGFBP3 protein
[Dietary Fats co-treated with Vinyl Chloride] affects the expression of IGFBP3 protein 		CTD PMID:36892438 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Ihh Indian hedgehog increases expression EXP Vinyl Chloride results in increased expression of IHH mRNA CTD PMID:18579281 NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831 		JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon increases expression EXP Vinyl Chloride results in increased expression of IKBKE mRNA CTD PMID:18579281 NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA] CTD PMID:26962056 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il18 interleukin 18 decreases expression EXP Vinyl Chloride results in decreased expression of IL18 mRNA CTD PMID:34717031 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression 		EXP Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
Vinyl Chloride results in decreased expression of IL1B mRNA 		CTD PMID:26962056 PMID:34717031 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1r1 interleukin 1 receptor, type I decreases expression EXP Vinyl Chloride results in decreased expression of IL1R1 mRNA CTD PMID:18579281 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Il36a interleukin 36A increases expression EXP Vinyl Chloride results in increased expression of IL36A mRNA CTD PMID:18579281 NCBI chr 2:24,105,429...24,115,713
Ensembl chr 2:24,105,430...24,115,714 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression 		EXP Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
Vinyl Chloride results in decreased expression of IL6 mRNA 		CTD PMID:26962056 PMID:34717031 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Impact impact, RWD domain protein decreases expression EXP Vinyl Chloride results in decreased expression of IMPACT mRNA CTD PMID:18579281 NCBI chr18:13,087,747...13,126,007
Ensembl chr18:13,088,909...13,126,007 		JBrowse link
G Insig1 insulin induced gene 1 increases expression EXP Vinyl Chloride results in increased expression of INSIG1 mRNA CTD PMID:18579281 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660 		JBrowse link
G Kel Kell blood group increases expression EXP Vinyl Chloride results in increased expression of KEL mRNA CTD PMID:18579281 NCBI chr 6:41,663,263...41,681,268
Ensembl chr 6:41,663,264...41,681,273 		JBrowse link
G Klhl31 kelch-like 31 increases expression EXP Vinyl Chloride results in increased expression of KLHL31 mRNA CTD PMID:18579281 NCBI chr 9:77,544,014...77,567,407
Ensembl chr 9:77,543,782...77,567,409 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions
increases response to substance
increases mutagenesis 		ISO
EXP 		CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]
KRAS gene polymorphism results in increased susceptibility to Vinyl Chloride 		CTD PMID:10629081 PMID:11563603 PMID:12211074 PMID:12670519 PMID:12705718 More... NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Krtap6-1 keratin associated protein 6-1 increases expression EXP Vinyl Chloride results in increased expression of KRTAP6-1 mRNA CTD PMID:18579281 NCBI chr16:88,828,587...88,829,180
Ensembl chr16:88,828,587...88,829,180 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator multiple interactions EXP [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of LARP1 mRNA CTD PMID:37061008 NCBI chr11:57,899,711...57,952,860
Ensembl chr11:57,899,890...57,952,860 		JBrowse link
G Lce1c late cornified envelope 1C increases expression EXP Vinyl Chloride results in increased expression of LCE1C mRNA CTD PMID:18579281 NCBI chr 3:92,586,554...92,588,225
Ensembl chr 3:92,586,554...92,588,225 		JBrowse link
G Lce1g late cornified envelope 1G increases expression EXP Vinyl Chloride results in increased expression of LCE1G mRNA CTD PMID:18579281 NCBI chr 3:92,657,458...92,659,645
Ensembl chr 3:92,657,455...92,659,645 		JBrowse link
G Lce3e late cornified envelope 3E increases expression EXP Vinyl Chloride results in increased expression of LCE3C mRNA CTD PMID:18579281 NCBI chr 3:92,874,368...92,875,588
Ensembl chr 3:92,874,368...92,875,588 		JBrowse link
G Lpar4 lysophosphatidic acid receptor 4 decreases expression EXP Vinyl Chloride results in decreased expression of LPAR4 mRNA CTD PMID:18579281 NCBI chr  X:105,964,231...105,977,505
Ensembl chr  X:105,964,231...105,977,506 		JBrowse link
G Lrrc49 leucine rich repeat containing 49 decreases expression EXP Vinyl Chloride results in decreased expression of LRRC49 mRNA CTD PMID:18579281 NCBI chr 9:60,494,507...60,595,460
Ensembl chr 9:60,476,142...60,595,441 		JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 increases expression EXP Vinyl Chloride results in increased expression of LRTM1 mRNA CTD PMID:18579281 NCBI chr14:28,740,165...28,755,599
Ensembl chr14:28,740,165...28,755,602 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression EXP Vinyl Chloride results in decreased expression of MAP3K5 mRNA CTD PMID:18579281 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 increases expression EXP Vinyl Chloride results in increased expression of MAPK8IP2 mRNA CTD PMID:18579281 NCBI chr15:89,338,114...89,346,650
Ensembl chr15:89,338,116...89,348,671 		JBrowse link
G Mcf2l mcf.2 transforming sequence-like increases expression EXP Vinyl Chloride results in increased expression of MCF2L mRNA CTD PMID:18579281 NCBI chr 8:12,923,806...13,070,502
Ensembl chr 8:12,923,806...13,070,905 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 affects response to substance ISO MDM2 polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic increases expression EXP Vinyl Chloride results in increased expression of ME1 mRNA CTD PMID:18579281 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006 		JBrowse link
G Med1 mediator complex subunit 1 decreases expression EXP Vinyl Chloride results in decreased expression of MED1 mRNA CTD PMID:18579281 NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119 		JBrowse link
G Meis1 Meis homeobox 1 increases expression EXP Vinyl Chloride results in increased expression of MEIS1 mRNA CTD PMID:18579281 NCBI chr11:18,830,428...18,968,992
Ensembl chr11:18,829,817...18,968,985 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO Vinyl Chloride results in decreased expression of MGMT protein CTD PMID:15256147 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) increases expression EXP Vinyl Chloride results in increased expression of MID1IP1 mRNA CTD PMID:18579281 NCBI chr  X:10,583,604...10,585,941
Ensembl chr  X:10,581,252...10,585,929 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions EXP [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of MKI67 protein CTD PMID:37061008 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions
increases expression 		EXP [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of MLXIPL mRNA
Vinyl Chloride results in increased expression of MLXIPL mRNA 		CTD PMID:37061008 NCBI chr 5:135,118,744...135,168,622
Ensembl chr 5:135,118,744...135,167,236 		JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component increases expression EXP Vinyl Chloride results in increased expression of MPDZ mRNA CTD PMID:18579281 NCBI chr 4:81,196,736...81,361,112
Ensembl chr 4:81,196,742...81,361,052 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases expression ISO Vinyl Chloride analog results in increased expression of MPG mRNA CTD PMID:10882851 NCBI chr11:32,176,505...32,182,702
Ensembl chr11:32,176,505...32,182,700 		JBrowse link
G Mt1 metallothionein 1 decreases expression EXP Vinyl Chloride results in decreased expression of MT1 mRNA CTD PMID:18579281 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955 		JBrowse link
G Mt4 metallothionein 4 decreases expression EXP Vinyl Chloride results in decreased expression of MT4 mRNA CTD PMID:18579281 NCBI chr 8:94,863,832...94,865,659
Ensembl chr 8:94,863,825...94,865,659 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation EXP Vinyl Chloride metabolite results in increased phosphorylation of MTOR protein CTD PMID:26962056 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Mvd mevalonate (diphospho) decarboxylase increases expression EXP Vinyl Chloride results in increased expression of MVD mRNA CTD PMID:18579281 NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161 		JBrowse link
G Mycn v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived increases expression
multiple interactions 		EXP Vinyl Chloride results in increased expression of MYCN mRNA
[Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of MYCN mRNA 		CTD PMID:37061008 NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915 		JBrowse link
G Nefl neurofilament, light polypeptide increases expression EXP Vinyl Chloride results in increased expression of NEFL mRNA CTD PMID:18579281 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544 		JBrowse link
G Niban2 niban apoptosis regulator 2 increases expression EXP Vinyl Chloride results in increased expression of NIBAN2 mRNA CTD PMID:18579281 NCBI chr 2:32,766,146...32,815,265
Ensembl chr 2:32,766,126...32,815,266 		JBrowse link
G Nip7 NIP7, nucleolar pre-rRNA processing protein decreases expression EXP Vinyl Chloride results in decreased expression of NIP7 mRNA CTD PMID:18579281 NCBI chr 8:107,783,509...107,787,563
Ensembl chr 8:107,783,509...107,787,563 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:26962056 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Olfml2b olfactomedin-like 2B increases expression EXP Vinyl Chloride results in increased expression of OLFML2B mRNA CTD PMID:18579281 NCBI chr 1:170,472,101...170,510,356
Ensembl chr 1:170,472,101...170,510,358 		JBrowse link
G Or5ac24 olfactory receptor family 5 subfamily AC member 24 increases expression EXP Vinyl Chloride results in increased expression of OR5AC24 mRNA CTD PMID:18579281 NCBI chr16:59,165,085...59,166,089
Ensembl chr16:59,165,038...59,169,609 		JBrowse link
G Or5b99 olfactory receptor family 5 subfamily B member 99 increases expression EXP Vinyl Chloride results in increased expression of OR5B99 mRNA CTD PMID:18579281 NCBI chr19:12,976,352...12,977,284
Ensembl chr19:12,972,378...12,977,781 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic decreases expression
increases expression 		EXP Vinyl Chloride results in decreased expression of PCK1 mRNA
Vinyl Chloride metabolite results in increased expression of PCK1 mRNA 		CTD PMID:18579281 PMID:26962056 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Vinyl Chloride co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PCNA protein CTD PMID:37061008 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression EXP Vinyl Chloride results in increased expression of PCSK9 mRNA CTD PMID:18579281 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526 		JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression EXP Vinyl Chloride results in decreased expression of PFKP mRNA CTD PMID:18579281 NCBI chr13:6,629,910...6,699,096
Ensembl chr13:6,629,804...6,698,813 		JBrowse link
G Pkd1l2 polycystic kidney disease 1 like 2 decreases expression EXP Vinyl Chloride results in decreased expression of PKD1L2 mRNA CTD PMID:18579281 NCBI chr 8:117,722,089...117,809,227
Ensembl chr 8:117,722,418...117,809,188 		JBrowse link
G Plch2 phospholipase C, eta 2 increases expression EXP Vinyl Chloride results in increased expression of PLCH2 mRNA CTD PMID:18579281 NCBI chr 4:155,067,572...155,148,548
Ensembl chr 4:155,067,572...155,141,241 		JBrowse link
G Plin4 perilipin 4 decreases expression EXP Vinyl Chloride results in decreased expression of PLIN4 mRNA CTD PMID:18579281 NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803 		JBrowse link
G Pnliprp2 pancreatic lipase-related protein 2 increases expression EXP Vinyl Chloride results in increased expression of PNLIPRP2 mRNA CTD PMID:18579281 NCBI chr19:58,748,155...58,765,966
Ensembl chr19:58,748,151...58,765,966 		JBrowse link
G Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) increases expression EXP Vinyl Chloride results in increased expression of POLE2 mRNA CTD PMID:18579281 NCBI chr12:69,248,547...69,274,979
Ensembl chr12:69,248,547...69,274,969 		JBrowse link
G Postn periostin, osteoblast specific factor increases expression EXP Vinyl Chloride results in increased expression of POSTN protein CTD PMID:36892438 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458 		JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression EXP Vinyl Chloride results in decreased expression of PPP1R3G mRNA CTD PMID:18579281 NCBI chr13:36,142,816...36,154,371
Ensembl chr13:36,142,822...36,154,371 		JBrowse link
G Prok1 prokineticin 1 increases expression EXP Vinyl Chloride results in increased expression of PROK1 mRNA CTD PMID:18579281 NCBI chr 3:107,139,232...107,147,023
Ensembl chr 3:107,140,113...107,147,023 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression EXP Vinyl Chloride results in increased expression of PSAT1 mRNA CTD PMID:18579281 NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701 		JBrowse link
G Pthlh parathyroid hormone-like peptide increases response to substance EXP PTHLH gene polymorphism results in increased susceptibility to Vinyl Chloride CTD PMID:12807761 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4a1 decreases expression EXP Vinyl Chloride results in decreased expression of PTP4A1 mRNA CTD PMID:18579281 NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390 		JBrowse link
G Raet1d retinoic acid early transcript delta increases expression EXP Vinyl Chloride results in increased expression of RAET1D mRNA CTD PMID:18579281 NCBI chr10:22,181,145...22,250,042
Ensembl chr10:22,236,451...22,250,038 		JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression EXP Vinyl Chloride results in decreased expression of RETREG1 mRNA CTD PMID:18579281 NCBI chr15:25,840,795...25,973,782
Ensembl chr15:25,843,266...25,973,773 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 increases expression EXP Vinyl Chloride results in increased expression of RFTN1 mRNA CTD PMID:18579281 NCBI chr17:50,300,287...50,497,525
Ensembl chr17:50,299,285...50,497,702 		JBrowse link
G Rpl39l ribosomal protein L39-like increases expression EXP Vinyl Chloride results in increased expression of RPL39L mRNA CTD PMID:18579281 NCBI chr16:9,988,061...9,992,775
Ensembl chr16:9,988,090...9,992,775 		JBrowse link
G S100a10 S100 calcium binding protein A10 (calpactin) increases expression EXP Vinyl Chloride results in increased expression of S100A10 mRNA CTD PMID:18579281 NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950 		JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) decreases expression EXP Vinyl Chloride results in decreased expression of S100A9 mRNA CTD PMID:18579281 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028 		JBrowse link
G Saa1 serum amyloid A 1 decreases expression EXP Vinyl Chloride results in decreased expression of SAA1 mRNA CTD PMID:18579281 NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404 		JBrowse link
G Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 increases expression EXP Vinyl Chloride results in increased expression of SERPINA12 mRNA CTD PMID:18579281 NCBI chr12:103,995,028...104,010,702
Ensembl chr12:103,995,028...104,010,702 		JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 multiple interactions EXP Vinyl Chloride metabolite promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE2 mRNA] CTD PMID:26962056 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
G Shisa2 shisa family member 2 increases expression EXP Vinyl Chloride results in increased expression of SHISA2 mRNA CTD PMID:18579281 NCBI chr14:59,862,730...59,869,109
Ensembl chr14:59,862,757...59,869,109 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression EXP Vinyl Chloride metabolite results in increased expression of SLC2A4 mRNA CTD PMID:26962056 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Slc36a2 solute carrier family 36 (proton/amino acid symporter), member 2 increases expression EXP Vinyl Chloride results in increased expression of SLC36A2 mRNA CTD PMID:18579281 NCBI chr11:55,049,294...55,075,924
Ensembl chr11:55,049,296...55,075,903 		JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 decreases expression EXP Vinyl Chloride results in decreased expression of SLC39A14 mRNA CTD PMID:18579281 NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874 		JBrowse link
G Smim3 small integral membrane protein 3 increases expression EXP Vinyl Chloride results in increased expression of SMIM3 mRNA CTD PMID:18579281 NCBI chr18:60,607,263...60,635,055
Ensembl chr18:60,607,263...60,635,059 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression EXP Vinyl Chloride results in decreased expression of SOCS3 mRNA CTD PMID:18579281 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular decreases expression EXP Vinyl Chloride results in decreased expression of SOD3 protein CTD PMID:34717031 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760 		JBrowse link
G Sorbs3 sorbin and SH3 domain containing 3 decreases expression EXP Vinyl Chloride results in decreased expression of SORBS3 mRNA CTD PMID:18579281 NCBI chr14:70,417,917...70,449,472
Ensembl chr14:70,417,917...70,449,438 		JBrowse link
G Spon2 spondin 2, extracellular matrix protein increases expression EXP Vinyl Chloride results in increased expression of SPON2 mRNA CTD PMID:18579281 NCBI chr 5:33,370,862...33,375,596
Ensembl chr 5:33,355,528...33,375,799 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP Vinyl Chloride results in increased expression of SREBF1 mRNA CTD PMID:18579281 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression EXP Vinyl Chloride results in decreased expression of ST3GAL5 mRNA CTD PMID:18579281 NCBI chr 6:72,074,555...72,131,555
Ensembl chr 6:72,074,576...72,131,555 		JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression EXP Vinyl Chloride results in decreased expression of TACC2 mRNA CTD PMID:18579281 NCBI chr 7:130,154,735...130,369,435
Ensembl chr 7:130,179,168...130,366,515 		JBrowse link
G Tango2 transport and golgi organization 2 decreases expression EXP Vinyl Chloride results in decreased expression of TANGO2 mRNA CTD PMID:18579281 NCBI chr16:18,118,689...18,165,962
Ensembl chr16:18,118,689...18,165,967 		JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression EXP Vinyl Chloride results in decreased expression of TBC1D8 mRNA CTD PMID:18579281 NCBI chr 1:39,410,576...39,517,860
Ensembl chr 1:39,410,573...39,517,836 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Dietary Fats co-treated with Vinyl Chloride] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Vinyl Chloride] results in increased secretion of TNF protein CTD PMID:31774537 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tom1l2 target of myb1-like 2 (chicken) decreases expression EXP Vinyl Chloride results in decreased expression of TOM1L2 mRNA CTD PMID:18579281 NCBI chr11:60,114,622...60,243,766
Ensembl chr11:60,117,540...60,243,731 		JBrowse link
G Top2a topoisomerase (DNA) II alpha increases activity ISO Vinyl Chloride metabolite results in increased activity of TOP2A protein CTD PMID:15751973 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Traf2 TNF receptor-associated factor 2 increases expression EXP Vinyl Chloride results in increased expression of TRAF2 mRNA CTD PMID:18579281 NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases response to substance
increases mutagenesis
increases expression
decreases expression
affects response to substance 		ISO CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]; GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]
TP53 gene SNP results in increased susceptibility to Vinyl Chloride
Vinyl Chloride results in increased expression of TP53 protein; Vinyl Chloride results in increased expression of TP53 protein mutant form
Vinyl Chloride results in decreased expression of TP53 mRNA
TP53 polymorphism affects the susceptibility to Vinyl Chloride 		CTD PMID:12010862 PMID:12670519 PMID:12705718 PMID:14602524 PMID:14979067 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 decreases expression EXP Vinyl Chloride results in decreased expression of TRP53INP1 mRNA CTD PMID:18579281 NCBI chr 4:11,156,441...11,174,379
Ensembl chr 4:11,156,431...11,174,379 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression EXP Vinyl Chloride results in increased expression of TSC22D1 mRNA CTD PMID:18579281 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205 		JBrowse link
G Ttc23 tetratricopeptide repeat domain 23 increases expression EXP Vinyl Chloride results in increased expression of TTC23 mRNA CTD PMID:18579281 NCBI chr 7:67,295,180...67,378,370
Ensembl chr 7:67,297,158...67,412,660 		JBrowse link
G Ust uronyl-2-sulfotransferase increases expression EXP Vinyl Chloride results in increased expression of UST mRNA CTD PMID:18579281 NCBI chr10:8,068,499...8,394,701
Ensembl chr10:8,080,520...8,394,589 		JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression EXP Vinyl Chloride results in decreased expression of VAMP1 mRNA CTD PMID:18579281 NCBI chr 6:125,192,544...125,199,269
Ensembl chr 6:125,192,514...125,222,927 		JBrowse link
G Vangl2 VANGL planar cell polarity 2 increases expression EXP Vinyl Chloride results in increased expression of VANGL2 mRNA CTD PMID:18579281 NCBI chr 1:171,828,527...171,856,532
Ensembl chr 1:171,828,527...171,856,011 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Vinyl Chloride metabolite inhibits the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA] CTD PMID:26962056 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 increases expression EXP Vinyl Chloride results in increased expression of VEPH1 mRNA CTD PMID:18579281 NCBI chr 3:65,960,979...66,204,370
Ensembl chr 3:65,960,979...66,204,258 		JBrowse link
G Wbp1l WW domain binding protein 1 like decreases expression EXP Vinyl Chloride results in decreased expression of WBP1L mRNA CTD PMID:18579281 NCBI chr19:46,587,545...46,645,828
Ensembl chr19:46,587,523...46,645,828 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A affects response to substance ISO XPA gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:21216194 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
G Xpc xeroderma pigmentosum, complementation group C affects response to substance ISO XPC gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:21216194 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870 		JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 multiple interactions
decreases expression
increases response to substance 		ISO GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; GSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]; XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]
Vinyl Chloride results in decreased expression of XRCC1 protein
XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride 		CTD PMID:12010862 PMID:14602524 PMID:15256147 PMID:16097394 PMID:16881598 More... NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865 		JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 affects response to substance ISO XRCC2 gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:16217922 NCBI chr 5:25,894,812...25,910,795
Ensembl chr 5:25,894,810...25,910,823 		JBrowse link
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 increases expression ISO Vinyl Chloride results in increased expression of XRCC3 protein CTD PMID:15256147 NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307 		JBrowse link
G Ypel1 yippee like 1 increases expression EXP Vinyl Chloride results in increased expression of YPEL1 mRNA CTD PMID:18579281 NCBI chr16:16,887,454...16,904,912
Ensembl chr16:16,887,560...16,904,909 		JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 decreases expression EXP Vinyl Chloride results in decreased expression of ZHX3 mRNA CTD PMID:18579281 NCBI chr 2:160,612,367...160,714,910
Ensembl chr 2:160,590,628...160,714,918 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22491
    chemical entity 22490
      molecular entity 22482
        main group molecular entity 22379
          gas molecular entity 9599
            chloroethene 182
Path 2
Term Annotations click to browse term
  CHEBI ontology 22491
    subatomic particle 22497
      composite particle 22497
        hadron 22485
          baryon 22497
            nucleon 22485
              atomic nucleus 22497
                atom 22485
                  main group element atom 22367
                    p-block element atom 22367
                      carbon group element atom 22156
                        carbon atom 22093
                          organic molecular entity 22093
                            heteroorganic entity 21745
                              organohalogen compound 20152
                                halohydrocarbon 15391
                                  chlorohydrocarbon 12176
                                    chloroolefin 8225
                                      chloroalkene 7661
                                        chloroethenes 7660
                                          chloroethene 182
paths to the root