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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tolazoline
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Accession:CHEBI:28502 term browser browse the term
Definition:A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Synonyms:exact_synonym: 2-benzyl-4,5-dihydro-1H-imidazole
 related_synonym: 2-Benzyl-2-imidazoline;   2-Benzyl-4,5-imidazoline;   2-Benzylimidazoline;   4,5-Dihydro-2-(phenylmethyl)-1H-imidazole;   Formula=C10H12N2;   InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12);   InChIKey=JIVZKJJQOZQXQB-UHFFFAOYSA-N;   SMILES=C1CN=C(Cc2ccccc2)N1
 alt_id: CHEBI:27018;   CHEBI:9614
 xref: CAS:59-98-3;   DrugBank:DB00797;   Drug_Central:2695;   HMDB:HMDB0014935;   KEGG:C07147;   KEGG:D08614;   LINCS:LSM-3020
 xref_mesh: MESH:D014043
 xref: PMID:14366198;   PMID:23321455;   PMID:23438114;   Reaxys:128757;   Wikipedia:Tolazoline


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tolazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Tolazoline co-treated with Glucose] binds to PPARA protein; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tolazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      application 19682
        pharmaceutical 19517
          drug 19517
            cardiovascular drug 8642
              antihypertensive agent 1946
                tolazoline 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            organic molecule 19692
                              organic cyclic compound 19482
                                organic heterocyclic compound 18872
                                  heteroarene 17151
                                    monocyclic heteroarene 14980
                                      azole 14505
                                        diazole 10772
                                          imidazoles 10222
                                            tolazoline 2
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